Mutagenetix > Incidental Mutation

Incidental Mutation 'R7177:Sdk2'

558710

Institutional Source

Beutler Lab

Gene Symbol

Sdk2

Ensembl Gene

ENSMUSG00000041592

Gene Name

sidekick cell adhesion molecule 2

Synonyms

4632412F08Rik, 5330435L01Rik

MMRRC Submission

045268-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.069) question?

Stock #

R7177 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

113667200-113957855 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 113720795 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Arginine to Histidine at position 1378 (R1378H)

Ref Sequence

ENSEMBL: ENSMUSP00000038972 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000041627]

AlphaFold

Q6V4S5

Predicted Effect

possibly damaging
Transcript: ENSMUST00000041627
AA Change: R1378H

PolyPhen 2 Score 0.910 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000038972
Gene: ENSMUSG00000041592
AA Change: R1378H

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
IGc2	43	102	4.67e-4	SMART
IG	123	208	6.07e-3	SMART
IG	225	309	1.4e-7	SMART
IGc2	325	391	6.21e-9	SMART
IGc2	418	486	8.57e-12	SMART
IG	506	591	2.37e-5	SMART
FN3	594	678	1.91e-7	SMART
FN3	694	780	2.42e-9	SMART
FN3	796	884	3.45e-5	SMART
FN3	899	981	2.36e-12	SMART
FN3	997	1084	1.64e-6	SMART
FN3	1101	1188	8.83e-12	SMART
FN3	1204	1289	3.62e-8	SMART
FN3	1305	1388	1.74e-10	SMART
FN3	1404	1489	8.23e-12	SMART
FN3	1506	1612	3.62e-8	SMART
FN3	1628	1713	1.15e-10	SMART
FN3	1728	1815	2.17e-11	SMART
FN3	1829	1913	5.04e-7	SMART
transmembrane domain	1935	1957	N/A	INTRINSIC
low complexity region	2138	2153	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 98.9%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired interconnectvity between VG3 amacrine cells and W3B retinal ganglion cells. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 75 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930550C14Rik	T	C	9: 53,325,685 (GRCm39)	L74S	probably damaging	Het
5730409E04Rik	A	G	4: 126,505,525 (GRCm39)	S18G	probably benign	Het
Adam29	A	G	8: 56,325,659 (GRCm39)	I265T	probably benign	Het
Aff4	C	T	11: 53,297,466 (GRCm39)	S896L	probably benign	Het
Ankrd27	T	C	7: 35,318,822 (GRCm39)	I571T	probably damaging	Het
Bdp1	C	A	13: 100,186,478 (GRCm39)	R1658I	probably damaging	Het
Carm1	C	T	9: 21,458,323 (GRCm39)	T7M	unknown	Het
Ccdc183	A	G	2: 25,506,296 (GRCm39)	V100A	probably damaging	Het
Cd86	CA	CAA	16: 36,426,917 (GRCm39)		probably null	Het
Ceacam2	T	G	7: 25,220,341 (GRCm39)	D239A	probably benign	Het
Cfap96	T	A	8: 46,423,444 (GRCm39)	E89D	possibly damaging	Het
Cimap1c	T	A	9: 56,757,262 (GRCm39)	M139L	possibly damaging	Het
Cmya5	T	C	13: 93,231,836 (GRCm39)	D1084G	probably benign	Het
Cog5	T	A	12: 31,810,888 (GRCm39)	I194K	probably damaging	Het
Col20a1	C	T	2: 180,636,007 (GRCm39)	Q211*	probably null	Het
Col9a1	T	A	1: 24,234,498 (GRCm39)	L13Q	unknown	Het
Cracr2a	A	T	6: 127,585,669 (GRCm39)	M156L	probably benign	Het
Cts8	C	T	13: 61,399,505 (GRCm39)	M151I	possibly damaging	Het
Cyp2ab1	A	T	16: 20,135,469 (GRCm39)	L11Q	probably null	Het
Dhrs13	T	A	11: 77,925,208 (GRCm39)	C160S	probably benign	Het
Enthd1	T	A	15: 80,358,415 (GRCm39)	E368D	probably damaging	Het
Fbh1	A	G	2: 11,760,522 (GRCm39)	I676T	probably damaging	Het
Fcgrt	T	C	7: 44,751,421 (GRCm39)	R176G	probably benign	Het
Gatd1	A	G	7: 140,990,947 (GRCm39)	F67L	possibly damaging	Het
Gm4353	G	A	7: 115,683,727 (GRCm39)	P23S	probably damaging	Het
Gm6882	T	A	7: 21,161,677 (GRCm39)	I64F	possibly damaging	Het
Grwd1	A	T	7: 45,480,204 (GRCm39)	M1K	probably null	Het
Hook2	T	A	8: 85,718,046 (GRCm39)	S58T	probably benign	Het
Iqch	T	G	9: 63,329,117 (GRCm39)	*1072C	probably null	Het
Kmt2d	G	A	15: 98,748,267 (GRCm39)	T3019I	unknown	Het
Lmx1a	T	C	1: 167,674,247 (GRCm39)	S356P	probably benign	Het
Lrig3	A	G	10: 125,842,712 (GRCm39)	M546V	probably benign	Het
Lrrc1	C	A	9: 77,379,504 (GRCm39)	E96*	probably null	Het
Lrtm2	C	A	6: 119,294,113 (GRCm39)	M339I	probably damaging	Het
Map10	T	C	8: 126,398,584 (GRCm39)	V659A	probably benign	Het
Map7d1	A	G	4: 126,130,778 (GRCm39)	C384R	probably damaging	Het
Mcur1	T	C	13: 43,698,012 (GRCm39)	D296G	probably damaging	Het
Mettl24	A	T	10: 40,686,508 (GRCm39)	H295L	probably damaging	Het
Mgat4f	T	C	1: 134,318,163 (GRCm39)	S312P	probably benign	Het
Mpl	A	G	4: 118,305,741 (GRCm39)		probably null	Het
Mrps5	T	C	2: 127,437,617 (GRCm39)	V148A	probably benign	Het
N4bp2	T	C	5: 65,964,891 (GRCm39)	V980A	probably damaging	Het
Ncaph	A	T	2: 126,958,506 (GRCm39)	D504E	probably damaging	Het
Nxph1	A	G	6: 9,247,497 (GRCm39)	N156S	probably damaging	Het
Or2t26	T	A	11: 49,040,012 (GRCm39)	C309*	probably null	Het
Or4f14b	T	A	2: 111,775,501 (GRCm39)	Q100L	probably damaging	Het
Pafah1b3	T	A	7: 24,994,657 (GRCm39)	I186L	probably benign	Het
Papola	C	A	12: 105,775,790 (GRCm39)	N235K	possibly damaging	Het
Pcnx3	A	T	19: 5,737,527 (GRCm39)	M98K	probably benign	Het
Pip4p1	A	C	14: 51,167,634 (GRCm39)	M104R	possibly damaging	Het
Pkhd1l1	A	G	15: 44,330,800 (GRCm39)	N125S	probably damaging	Het
Pls1	T	A	9: 95,655,612 (GRCm39)	H380L	probably benign	Het
Plxna1	T	C	6: 89,300,311 (GRCm39)	T1591A	possibly damaging	Het
Pparg	T	G	6: 115,418,581 (GRCm39)	S147A	probably benign	Het
Prdm10	T	C	9: 31,279,003 (GRCm39)	S1025P	probably benign	Het
Prkcd	T	A	14: 30,321,664 (GRCm39)	H510L	probably damaging	Het
Ptprh	T	A	7: 4,572,480 (GRCm39)	E499D	possibly damaging	Het
Rad51ap1	A	G	6: 126,901,983 (GRCm39)	S256P	probably benign	Het
Rad54b	A	G	4: 11,599,755 (GRCm39)	T320A	probably damaging	Het
Rnf207	A	G	4: 152,396,634 (GRCm39)	I459T	probably benign	Het
Runx2	G	A	17: 45,125,079 (GRCm39)	P80L	probably damaging	Het
Ryr3	A	T	2: 112,731,188 (GRCm39)	D727E	probably damaging	Het
Slc7a11	A	G	3: 50,397,680 (GRCm39)	S11P	probably benign	Het
Sox4	A	G	13: 29,137,000 (GRCm39)	V2A	probably damaging	Het
Srf	A	G	17: 46,866,318 (GRCm39)	F146S	probably damaging	Het
Srrm2	T	C	17: 24,035,747 (GRCm39)	V797A	unknown	Het
Stk32c	T	C	7: 138,684,218 (GRCm39)	D463G	possibly damaging	Het
Syne2	C	A	12: 76,018,654 (GRCm39)	Y3384*	probably null	Het
Tektl1	T	C	10: 78,588,324 (GRCm39)	D162G	probably damaging	Het
Traip	T	A	9: 107,838,184 (GRCm39)	M139K	possibly damaging	Het
Trappc2l	T	A	8: 123,341,051 (GRCm39)	F100Y	probably damaging	Het
Ush1c	T	C	7: 45,878,643 (GRCm39)	D124G	probably damaging	Het
Uty	A	G	Y: 1,099,691 (GRCm39)	V1168A	probably benign	Het
Vmn2r25	T	C	6: 123,816,882 (GRCm39)	D233G	possibly damaging	Het
Zdbf2	C	T	1: 63,334,120 (GRCm39)	R31C	possibly damaging	Het

Other mutations in Sdk2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00972:Sdk2	APN	11	113,745,210 (GRCm39)	missense	possibly damaging	0.86
IGL01063:Sdk2	APN	11	113,721,668 (GRCm39)	missense	probably damaging	1.00
IGL01291:Sdk2	APN	11	113,733,906 (GRCm39)	missense	probably benign
IGL01316:Sdk2	APN	11	113,758,791 (GRCm39)	missense	probably benign	0.09
IGL01614:Sdk2	APN	11	113,684,684 (GRCm39)	missense	probably damaging	1.00
IGL01998:Sdk2	APN	11	113,729,358 (GRCm39)	missense	probably damaging	0.98
IGL02014:Sdk2	APN	11	113,729,320 (GRCm39)	missense	probably damaging	1.00
IGL02095:Sdk2	APN	11	113,725,656 (GRCm39)	missense	probably damaging	1.00
IGL02115:Sdk2	APN	11	113,725,639 (GRCm39)	splice site	probably benign
IGL02543:Sdk2	APN	11	113,759,747 (GRCm39)	missense	possibly damaging	0.90
IGL02976:Sdk2	APN	11	113,742,668 (GRCm39)	missense	probably damaging	1.00
IGL03001:Sdk2	APN	11	113,712,452 (GRCm39)	missense	probably benign	0.00
IGL03122:Sdk2	APN	11	113,732,894 (GRCm39)	missense	probably damaging	1.00
IGL03183:Sdk2	APN	11	113,741,810 (GRCm39)	missense	probably benign	0.19
IGL03222:Sdk2	APN	11	113,729,257 (GRCm39)	missense	probably benign	0.01
IGL03310:Sdk2	APN	11	113,684,151 (GRCm39)	missense	possibly damaging	0.77
Curtailed	UTSW	11	113,742,626 (GRCm39)	missense	probably damaging	1.00
Trimmed	UTSW	11	113,747,522 (GRCm39)	nonsense	probably null
ANU05:Sdk2	UTSW	11	113,733,906 (GRCm39)	missense	probably benign
BB008:Sdk2	UTSW	11	113,784,267 (GRCm39)	missense	possibly damaging	0.79
BB018:Sdk2	UTSW	11	113,784,267 (GRCm39)	missense	possibly damaging	0.79
R0008:Sdk2	UTSW	11	113,747,581 (GRCm39)	missense	probably damaging	1.00
R0008:Sdk2	UTSW	11	113,747,581 (GRCm39)	missense	probably damaging	1.00
R0088:Sdk2	UTSW	11	113,717,912 (GRCm39)	missense	possibly damaging	0.74
R0096:Sdk2	UTSW	11	113,793,970 (GRCm39)	splice site	probably benign
R0386:Sdk2	UTSW	11	113,784,290 (GRCm39)	missense	probably damaging	0.96
R0396:Sdk2	UTSW	11	113,720,793 (GRCm39)	missense	probably benign	0.04
R0409:Sdk2	UTSW	11	113,741,717 (GRCm39)	splice site	probably benign
R0416:Sdk2	UTSW	11	113,694,029 (GRCm39)	missense	probably damaging	1.00
R0456:Sdk2	UTSW	11	113,682,292 (GRCm39)	missense	possibly damaging	0.93
R0544:Sdk2	UTSW	11	113,671,836 (GRCm39)	missense	probably damaging	1.00
R0691:Sdk2	UTSW	11	113,685,746 (GRCm39)	splice site	probably null
R0711:Sdk2	UTSW	11	113,793,970 (GRCm39)	splice site	probably benign
R0717:Sdk2	UTSW	11	113,723,152 (GRCm39)	missense	probably damaging	1.00
R0780:Sdk2	UTSW	11	113,784,334 (GRCm39)	missense	probably benign	0.07
R0831:Sdk2	UTSW	11	113,723,084 (GRCm39)	missense	probably damaging	0.96
R0853:Sdk2	UTSW	11	113,712,241 (GRCm39)	missense	probably benign	0.00
R0865:Sdk2	UTSW	11	113,741,748 (GRCm39)	missense	probably benign	0.12
R0930:Sdk2	UTSW	11	113,729,271 (GRCm39)	missense	probably benign	0.01
R0964:Sdk2	UTSW	11	113,697,243 (GRCm39)	splice site	probably benign
R1051:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1052:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1054:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1055:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1077:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1079:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1115:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1186:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1187:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1337:Sdk2	UTSW	11	113,723,157 (GRCm39)	missense	possibly damaging	0.79
R1430:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1433:Sdk2	UTSW	11	113,685,871 (GRCm39)	missense	probably damaging	0.99
R1464:Sdk2	UTSW	11	113,720,906 (GRCm39)	missense	possibly damaging	0.86
R1464:Sdk2	UTSW	11	113,720,906 (GRCm39)	missense	possibly damaging	0.86
R1497:Sdk2	UTSW	11	113,784,401 (GRCm39)	splice site	probably benign
R1514:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1529:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1596:Sdk2	UTSW	11	113,729,435 (GRCm39)	splice site	probably benign
R1680:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1680:Sdk2	UTSW	11	113,682,262 (GRCm39)	missense	possibly damaging	0.47
R1770:Sdk2	UTSW	11	113,684,567 (GRCm39)	missense	probably benign	0.05
R1858:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1866:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1874:Sdk2	UTSW	11	113,725,782 (GRCm39)	missense	probably benign	0.00
R1899:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1905:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1907:Sdk2	UTSW	11	113,729,472 (GRCm39)	synonymous	silent
R1913:Sdk2	UTSW	11	113,747,552 (GRCm39)	missense	possibly damaging	0.77
R1964:Sdk2	UTSW	11	113,671,843 (GRCm39)	nonsense	probably null
R2055:Sdk2	UTSW	11	113,741,780 (GRCm39)	missense	probably damaging	1.00
R2059:Sdk2	UTSW	11	113,745,158 (GRCm39)	missense	probably damaging	1.00
R2093:Sdk2	UTSW	11	113,833,948 (GRCm39)	missense	probably damaging	1.00
R2256:Sdk2	UTSW	11	113,721,620 (GRCm39)	missense	probably benign	0.44
R3720:Sdk2	UTSW	11	113,691,070 (GRCm39)	missense	probably damaging	1.00
R3795:Sdk2	UTSW	11	113,747,522 (GRCm39)	nonsense	probably null
R4037:Sdk2	UTSW	11	113,685,881 (GRCm39)	missense	probably damaging	1.00
R4171:Sdk2	UTSW	11	113,757,815 (GRCm39)	splice site	probably null
R4717:Sdk2	UTSW	11	113,745,195 (GRCm39)	missense	probably damaging	0.96
R4758:Sdk2	UTSW	11	113,717,880 (GRCm39)	missense	possibly damaging	0.87
R4857:Sdk2	UTSW	11	113,712,208 (GRCm39)	nonsense	probably null
R4924:Sdk2	UTSW	11	113,748,584 (GRCm39)	missense	probably damaging	1.00
R5015:Sdk2	UTSW	11	113,684,587 (GRCm39)	missense	probably damaging	1.00
R5171:Sdk2	UTSW	11	113,741,808 (GRCm39)	missense	probably benign	0.01
R5239:Sdk2	UTSW	11	113,758,859 (GRCm39)	missense	probably damaging	1.00
R5243:Sdk2	UTSW	11	113,715,912 (GRCm39)	missense	possibly damaging	0.76
R5279:Sdk2	UTSW	11	113,757,857 (GRCm39)	missense	probably benign	0.31
R5535:Sdk2	UTSW	11	113,833,984 (GRCm39)	missense	possibly damaging	0.80
R5634:Sdk2	UTSW	11	113,742,540 (GRCm39)	missense	probably damaging	1.00
R5637:Sdk2	UTSW	11	113,724,005 (GRCm39)	missense	probably damaging	1.00
R5726:Sdk2	UTSW	11	113,742,626 (GRCm39)	missense	probably damaging	1.00
R5793:Sdk2	UTSW	11	113,759,778 (GRCm39)	missense	possibly damaging	0.46
R5798:Sdk2	UTSW	11	113,717,942 (GRCm39)	missense	probably damaging	1.00
R5834:Sdk2	UTSW	11	113,745,099 (GRCm39)	missense	probably damaging	1.00
R5863:Sdk2	UTSW	11	113,725,810 (GRCm39)	missense	probably damaging	0.98
R5869:Sdk2	UTSW	11	113,742,708 (GRCm39)	missense	probably damaging	0.96
R5875:Sdk2	UTSW	11	113,720,885 (GRCm39)	missense	probably benign	0.00
R5953:Sdk2	UTSW	11	113,684,570 (GRCm39)	missense	probably damaging	1.00
R5991:Sdk2	UTSW	11	113,834,080 (GRCm39)	missense	probably damaging	0.97
R6018:Sdk2	UTSW	11	113,720,889 (GRCm39)	missense	probably benign	0.00
R6116:Sdk2	UTSW	11	113,745,190 (GRCm39)	missense	probably damaging	0.99
R6328:Sdk2	UTSW	11	113,684,581 (GRCm39)	missense	probably damaging	1.00
R6348:Sdk2	UTSW	11	113,784,334 (GRCm39)	missense	probably benign	0.07
R6383:Sdk2	UTSW	11	113,723,091 (GRCm39)	missense	probably damaging	1.00
R6824:Sdk2	UTSW	11	113,758,760 (GRCm39)	missense	probably benign	0.43
R6835:Sdk2	UTSW	11	113,720,874 (GRCm39)	missense	probably damaging	0.98
R6853:Sdk2	UTSW	11	113,671,755 (GRCm39)	missense	probably damaging	0.99
R6912:Sdk2	UTSW	11	113,793,946 (GRCm39)	missense	probably benign	0.03
R7000:Sdk2	UTSW	11	113,693,995 (GRCm39)	missense	probably damaging	1.00
R7099:Sdk2	UTSW	11	113,725,731 (GRCm39)	missense	probably damaging	0.98
R7102:Sdk2	UTSW	11	113,733,516 (GRCm39)	nonsense	probably null
R7381:Sdk2	UTSW	11	113,729,315 (GRCm39)	missense	probably damaging	0.98
R7412:Sdk2	UTSW	11	113,758,909 (GRCm39)	splice site	probably null
R7504:Sdk2	UTSW	11	113,758,793 (GRCm39)	missense	possibly damaging	0.50
R7552:Sdk2	UTSW	11	113,764,039 (GRCm39)	missense	possibly damaging	0.63
R7604:Sdk2	UTSW	11	113,720,795 (GRCm39)	missense	possibly damaging	0.91
R7647:Sdk2	UTSW	11	113,684,563 (GRCm39)	missense	probably damaging	1.00
R7897:Sdk2	UTSW	11	113,764,027 (GRCm39)	missense	possibly damaging	0.50
R7931:Sdk2	UTSW	11	113,784,267 (GRCm39)	missense	possibly damaging	0.79
R7998:Sdk2	UTSW	11	113,750,764 (GRCm39)	missense	probably benign	0.18
R8052:Sdk2	UTSW	11	113,745,177 (GRCm39)	missense	probably damaging	1.00
R8053:Sdk2	UTSW	11	113,745,177 (GRCm39)	missense	probably damaging	1.00
R8084:Sdk2	UTSW	11	113,717,915 (GRCm39)	missense	possibly damaging	0.67
R8136:Sdk2	UTSW	11	113,742,539 (GRCm39)	missense	probably damaging	1.00
R8151:Sdk2	UTSW	11	113,763,683 (GRCm39)	missense	possibly damaging	0.84
R8394:Sdk2	UTSW	11	113,729,542 (GRCm39)	missense	probably benign
R8715:Sdk2	UTSW	11	113,671,728 (GRCm39)	missense	probably damaging	1.00
R8774:Sdk2	UTSW	11	113,730,169 (GRCm39)	missense	probably damaging	1.00
R8774-TAIL:Sdk2	UTSW	11	113,730,169 (GRCm39)	missense	probably damaging	1.00
R8804:Sdk2	UTSW	11	113,763,978 (GRCm39)	nonsense	probably null
R9136:Sdk2	UTSW	11	113,697,203 (GRCm39)	missense	probably damaging	1.00
R9147:Sdk2	UTSW	11	113,714,226 (GRCm39)	missense	probably benign	0.18
R9300:Sdk2	UTSW	11	113,715,856 (GRCm39)	missense	possibly damaging	0.63
R9354:Sdk2	UTSW	11	113,725,757 (GRCm39)	missense	probably benign	0.00
R9450:Sdk2	UTSW	11	113,697,105 (GRCm39)	missense	probably benign
R9462:Sdk2	UTSW	11	113,760,744 (GRCm39)	missense	possibly damaging	0.56
R9616:Sdk2	UTSW	11	113,691,061 (GRCm39)	missense	probably benign	0.05
R9678:Sdk2	UTSW	11	113,685,789 (GRCm39)	nonsense	probably null
RF002:Sdk2	UTSW	11	113,776,078 (GRCm39)	missense	probably benign	0.00
V1662:Sdk2	UTSW	11	113,725,734 (GRCm39)	missense	probably damaging	1.00
Z1176:Sdk2	UTSW	11	113,742,662 (GRCm39)	missense	probably damaging	0.97
Z1176:Sdk2	UTSW	11	113,730,148 (GRCm39)	missense	probably benign	0.41
Z1177:Sdk2	UTSW	11	113,750,782 (GRCm39)	missense	probably benign
Z1177:Sdk2	UTSW	11	113,730,146 (GRCm39)	missense	probably damaging	1.00
Z1177:Sdk2	UTSW	11	113,729,485 (GRCm39)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- CTAAAGCAATGCCGTTCCCC -3'
(R):5'- AGAGATGGGTCCTCTCACAG -3'

Sequencing Primer
(F):5'- TCCCAGTTGCCCACCAG -3'
(R):5'- CAGGACACTGGGGCTGC -3'

Posted On

2019-06-26