Mutagenetix > Incidental Mutation

Incidental Mutation 'R7188:Dnah12'

559448

Institutional Source

Beutler Lab

Gene Symbol

Dnah12

Ensembl Gene

ENSMUSG00000021879

Gene Name

dynein, axonemal, heavy chain 12

Synonyms

HL19, DHC3, Dnahc7l, 4921531P07Rik, HL-19, LOC380889, Hdhc3, Dnahc12, DLP12

MMRRC Submission

045272-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.196) question?

Stock #

R7188 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

26414429-26613660 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 26536370 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Asparagine at position 2095 (K2095N)

Ref Sequence

ENSEMBL: ENSMUSP00000022433 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000022433]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000022433
AA Change: K2095N

PolyPhen 2 Score 0.039 (Sensitivity: 0.94; Specificity: 0.83)

SMART Domains

Protein: ENSMUSP00000022433
Gene: ENSMUSG00000021879
AA Change: K2095N

Domain	Start	End	E-Value	Type
low complexity region	127	140	N/A	INTRINSIC
coiled coil region	588	666	N/A	INTRINSIC
Pfam:DHC_N2	676	1113	1.1e-147	PFAM
AAA	1268	1407	1.15e0	SMART
Pfam:AAA_5	1552	1695	1.5e-7	PFAM
Blast:AAA	1709	1827	2e-24	BLAST
Blast:AAA	1848	1898	1e-16	BLAST
AAA	1903	2051	5.42e-4	SMART
Pfam:AAA_8	2238	2316	2e-18	PFAM

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.3%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 66 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca17	T	C	17: 24,554,600 (GRCm39)	Y118C	possibly damaging	Het
Abcb6	A	G	1: 75,150,781 (GRCm39)		probably null	Het
Acox2	T	A	14: 8,252,996 (GRCm38)	I236L	possibly damaging	Het
Adamts12	A	T	15: 11,336,411 (GRCm39)	K1499*	probably null	Het
Ankrd24	G	T	10: 81,472,224 (GRCm39)	E20*	probably null	Het
Arsa	A	T	15: 89,359,830 (GRCm39)	Y32*	probably null	Het
Atp9b	A	G	18: 80,961,041 (GRCm39)	S57P		Het
Atr	G	T	9: 95,744,844 (GRCm39)	E54*	probably null	Het
Bace1	A	G	9: 45,767,393 (GRCm39)	D192G	probably benign	Het
Bltp1	A	T	3: 37,004,162 (GRCm39)	T1624S	probably benign	Het
Bltp3b	T	C	10: 89,615,744 (GRCm39)	V129A	probably damaging	Het
Cacna1d	T	C	14: 29,811,790 (GRCm39)	S1309G	probably benign	Het
Cd177	G	T	7: 24,456,072 (GRCm39)	T232K	probably damaging	Het
Chil4	T	A	3: 106,111,475 (GRCm39)	D213V	probably damaging	Het
Cmya5	A	T	13: 93,182,546 (GRCm39)	I3538N	probably damaging	Het
Cyp26a1	T	A	19: 37,687,753 (GRCm39)	M287K	possibly damaging	Het
Dcaf5	T	C	12: 80,446,732 (GRCm39)	D129G	probably damaging	Het
Dnpep	G	A	1: 75,292,701 (GRCm39)	S106L	probably damaging	Het
Dock2	C	T	11: 34,189,675 (GRCm39)	E1499K	possibly damaging	Het
Dus4l	A	G	12: 31,696,714 (GRCm39)	F88L	probably damaging	Het
Fcrl2	A	C	3: 87,166,830 (GRCm39)	D54E	probably benign	Het
Fign	T	A	2: 63,809,950 (GRCm39)	H440L	possibly damaging	Het
Gabpa	A	G	16: 84,643,174 (GRCm39)	D157G	probably damaging	Het
Gapdh	T	A	6: 125,142,403 (GRCm39)		probably benign	Het
Gbp8	G	T	5: 105,164,081 (GRCm39)	R406S	probably benign	Het
Gm21775	A	G	Y: 10,553,894 (GRCm39)	R148G	possibly damaging	Het
Gm28363	G	A	1: 117,626,579 (GRCm39)	V6I	unknown	Het
Gmps	A	G	3: 63,918,982 (GRCm39)	D522G	probably damaging	Het
Gpr75	T	C	11: 30,842,687 (GRCm39)	S531P	probably damaging	Het
Hars2	G	T	18: 36,923,614 (GRCm39)	E468D	probably benign	Het
Jph4	C	A	14: 55,352,664 (GRCm39)	R23L	probably damaging	Het
Kctd12	T	A	14: 103,219,230 (GRCm39)	Y216F	probably benign	Het
L3mbtl1	G	A	2: 162,791,460 (GRCm39)		probably null	Het
Lama4	G	A	10: 38,841,729 (GRCm39)		probably benign	Het
Lyst	T	A	13: 13,926,675 (GRCm39)	S3494T	possibly damaging	Het
Mybpc2	A	G	7: 44,155,617 (GRCm39)	S879P	probably benign	Het
Ncaph	C	T	2: 126,964,034 (GRCm39)	V304M	probably benign	Het
Noto	A	T	6: 85,405,047 (GRCm39)	I229F	possibly damaging	Het
Or10n7-ps1	T	C	9: 39,597,731 (GRCm39)	M170V	unknown	Het
Or4c29	T	C	2: 88,740,203 (GRCm39)	D178G	probably damaging	Het
Or8k25	T	A	2: 86,243,695 (GRCm39)	K234*	probably null	Het
Pald1	A	T	10: 61,182,845 (GRCm39)	V368E	probably damaging	Het
Pde9a	T	A	17: 31,678,071 (GRCm39)	M217K	probably damaging	Het
Pira1	A	T	7: 3,741,828 (GRCm39)	V184E	probably damaging	Het
Pitpnm2	G	T	5: 124,259,366 (GRCm39)	A1323E	probably benign	Het
Ppp1r3a	T	C	6: 14,719,190 (GRCm39)	S575G	probably benign	Het
Prok1	T	C	3: 107,146,941 (GRCm39)	I9V	probably benign	Het
Ptprc	A	T	1: 137,998,918 (GRCm39)	V905D	probably damaging	Het
Rbm25	G	T	12: 83,710,772 (GRCm39)	G295V	unknown	Het
Rreb1	T	C	13: 38,100,544 (GRCm39)	M225T	possibly damaging	Het
Ryr3	T	C	2: 112,858,989 (GRCm39)	K55E	probably damaging	Het
Saxo4	T	A	19: 10,459,702 (GRCm39)	M2L	probably benign	Het
Scgb2b26	G	T	7: 33,644,379 (GRCm39)	T4K	probably damaging	Het
Setx	C	A	2: 29,038,184 (GRCm39)	D1556E	probably benign	Het
Sft2d1	C	T	17: 8,542,164 (GRCm39)	T136I	possibly damaging	Het
Sirt5	C	T	13: 43,525,380 (GRCm39)	A63V	possibly damaging	Het
Skor2	A	G	18: 76,947,504 (GRCm39)	T409A	possibly damaging	Het
Slc12a6	T	C	2: 112,164,760 (GRCm39)	M153T	probably benign	Het
Slc34a1	A	G	13: 24,006,348 (GRCm39)	Y458C	probably damaging	Het
Slc36a2	A	G	11: 55,053,483 (GRCm39)	V385A	possibly damaging	Het
St6galnac5	A	T	3: 152,552,131 (GRCm39)	H145Q	probably damaging	Het
Tal1	T	A	4: 114,925,610 (GRCm39)	N226K	probably damaging	Het
Tgtp2	G	C	11: 48,950,135 (GRCm39)	R146G	probably damaging	Het
Usp6nl	T	C	2: 6,445,330 (GRCm39)	S436P	probably benign	Het
Utp3	A	G	5: 88,702,621 (GRCm39)	E50G	probably benign	Het
Zfp12	A	T	5: 143,225,749 (GRCm39)	Q19L	probably damaging	Het

Other mutations in Dnah12

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01412:Dnah12	APN	14	26,492,962 (GRCm39)	missense	probably damaging	1.00
IGL01602:Dnah12	APN	14	26,431,430 (GRCm39)	splice site	probably benign
IGL01681:Dnah12	APN	14	26,443,315 (GRCm39)	missense	probably benign
IGL02082:Dnah12	APN	14	26,428,317 (GRCm39)	missense	possibly damaging	0.79
IGL02140:Dnah12	APN	14	26,437,732 (GRCm39)	missense	probably benign	0.20
IGL02170:Dnah12	APN	14	26,495,069 (GRCm39)	missense	probably damaging	0.99
IGL02174:Dnah12	APN	14	26,428,072 (GRCm39)	missense	probably benign	0.00
IGL02367:Dnah12	APN	14	26,430,316 (GRCm39)	missense	probably benign	0.30
IGL02418:Dnah12	APN	14	26,495,679 (GRCm39)	missense	probably damaging	1.00
IGL03039:Dnah12	APN	14	26,445,667 (GRCm39)	missense	probably benign	0.02
IGL03066:Dnah12	APN	14	26,418,553 (GRCm39)	missense	probably benign	0.06
drippings	UTSW	14	26,576,761 (GRCm39)	missense	probably damaging	1.00
grueben	UTSW	14	26,600,036 (GRCm39)	missense	probably damaging	1.00
BB010:Dnah12	UTSW	14	26,488,072 (GRCm39)	missense	probably benign	0.00
BB020:Dnah12	UTSW	14	26,488,072 (GRCm39)	missense	probably benign	0.00
F5770:Dnah12	UTSW	14	26,495,050 (GRCm39)	missense	possibly damaging	0.95
FR4304:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
FR4340:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
FR4342:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
FR4589:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
IGL03055:Dnah12	UTSW	14	26,594,697 (GRCm39)	missense	probably damaging	1.00
LCD18:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
R0003:Dnah12	UTSW	14	26,494,601 (GRCm39)	missense	probably damaging	1.00
R0110:Dnah12	UTSW	14	26,520,856 (GRCm39)	missense	probably damaging	1.00
R0302:Dnah12	UTSW	14	26,521,956 (GRCm39)	missense	probably damaging	1.00
R0355:Dnah12	UTSW	14	26,427,272 (GRCm39)	splice site	probably null
R0364:Dnah12	UTSW	14	26,445,628 (GRCm39)	missense	probably benign	0.10
R0469:Dnah12	UTSW	14	26,520,856 (GRCm39)	missense	probably damaging	1.00
R0558:Dnah12	UTSW	14	26,430,465 (GRCm39)	missense	probably benign	0.00
R0709:Dnah12	UTSW	14	26,606,222 (GRCm39)	splice site	probably benign
R0734:Dnah12	UTSW	14	26,521,970 (GRCm39)	missense	probably benign	0.00
R1273:Dnah12	UTSW	14	26,460,375 (GRCm39)	nonsense	probably null
R1496:Dnah12	UTSW	14	26,431,403 (GRCm39)	missense	probably benign
R1503:Dnah12	UTSW	14	26,495,649 (GRCm39)	missense	probably damaging	1.00
R1535:Dnah12	UTSW	14	26,538,279 (GRCm39)	missense	possibly damaging	0.91
R1608:Dnah12	UTSW	14	26,488,147 (GRCm39)	missense	probably damaging	1.00
R1682:Dnah12	UTSW	14	26,500,840 (GRCm39)	missense	possibly damaging	0.71
R1758:Dnah12	UTSW	14	26,488,071 (GRCm39)	missense	probably benign	0.02
R1826:Dnah12	UTSW	14	26,432,174 (GRCm39)	missense	probably benign	0.01
R1829:Dnah12	UTSW	14	26,522,032 (GRCm39)	missense	probably damaging	1.00
R1829:Dnah12	UTSW	14	26,494,980 (GRCm39)	missense	probably damaging	1.00
R1862:Dnah12	UTSW	14	26,430,412 (GRCm39)	missense	probably benign	0.30
R1862:Dnah12	UTSW	14	26,418,553 (GRCm39)	missense	probably benign	0.06
R1913:Dnah12	UTSW	14	26,514,221 (GRCm39)	splice site	probably null
R1933:Dnah12	UTSW	14	26,455,650 (GRCm39)	missense	probably damaging	0.98
R2006:Dnah12	UTSW	14	26,536,416 (GRCm39)	missense	possibly damaging	0.95
R2045:Dnah12	UTSW	14	26,503,485 (GRCm39)	missense	probably null	1.00
R2113:Dnah12	UTSW	14	26,488,098 (GRCm39)	missense	probably damaging	1.00
R2125:Dnah12	UTSW	14	26,445,613 (GRCm39)	nonsense	probably null
R2126:Dnah12	UTSW	14	26,445,613 (GRCm39)	nonsense	probably null
R2207:Dnah12	UTSW	14	26,503,744 (GRCm39)	missense	probably damaging	0.99
R2213:Dnah12	UTSW	14	26,460,485 (GRCm39)	missense	probably benign	0.06
R2511:Dnah12	UTSW	14	26,491,907 (GRCm39)	missense	possibly damaging	0.65
R2875:Dnah12	UTSW	14	26,598,907 (GRCm39)	missense	probably benign	0.05
R2875:Dnah12	UTSW	14	26,414,625 (GRCm39)	missense	probably benign	0.04
R3551:Dnah12	UTSW	14	26,492,929 (GRCm39)	missense	probably benign	0.01
R3713:Dnah12	UTSW	14	26,534,747 (GRCm39)	missense	probably benign
R3729:Dnah12	UTSW	14	26,427,220 (GRCm39)	missense	probably benign	0.02
R3799:Dnah12	UTSW	14	26,492,880 (GRCm39)	missense	probably damaging	1.00
R3846:Dnah12	UTSW	14	26,431,366 (GRCm39)	missense	probably benign	0.00
R3892:Dnah12	UTSW	14	26,578,573 (GRCm39)	missense	probably benign	0.03
R3921:Dnah12	UTSW	14	26,493,008 (GRCm39)	missense	probably damaging	1.00
R3940:Dnah12	UTSW	14	26,444,754 (GRCm39)	missense	probably benign
R4065:Dnah12	UTSW	14	26,492,405 (GRCm39)	missense	probably benign	0.02
R4113:Dnah12	UTSW	14	26,414,722 (GRCm39)	missense	probably damaging	0.98
R4249:Dnah12	UTSW	14	26,430,341 (GRCm39)	missense	possibly damaging	0.70
R4259:Dnah12	UTSW	14	26,520,883 (GRCm39)	missense	probably benign	0.01
R4260:Dnah12	UTSW	14	26,520,883 (GRCm39)	missense	probably benign	0.01
R4348:Dnah12	UTSW	14	26,536,498 (GRCm39)	missense	possibly damaging	0.94
R4457:Dnah12	UTSW	14	26,537,464 (GRCm39)	missense	probably damaging	1.00
R4490:Dnah12	UTSW	14	26,455,758 (GRCm39)	missense	possibly damaging	0.67
R4491:Dnah12	UTSW	14	26,455,758 (GRCm39)	missense	possibly damaging	0.67
R4494:Dnah12	UTSW	14	26,593,812 (GRCm39)	missense	probably damaging	0.99
R4523:Dnah12	UTSW	14	26,598,915 (GRCm39)	missense	possibly damaging	0.83
R4523:Dnah12	UTSW	14	26,491,979 (GRCm39)	missense	probably damaging	0.97
R4546:Dnah12	UTSW	14	26,494,971 (GRCm39)	missense	probably damaging	1.00
R4584:Dnah12	UTSW	14	26,494,551 (GRCm39)	missense	probably damaging	1.00
R4624:Dnah12	UTSW	14	26,456,913 (GRCm39)	missense	possibly damaging	0.82
R4689:Dnah12	UTSW	14	26,427,994 (GRCm39)	missense	probably benign	0.00
R4727:Dnah12	UTSW	14	26,594,274 (GRCm39)	missense	probably damaging	1.00
R4732:Dnah12	UTSW	14	26,503,741 (GRCm39)	missense	probably damaging	1.00
R4733:Dnah12	UTSW	14	26,503,741 (GRCm39)	missense	probably damaging	1.00
R4851:Dnah12	UTSW	14	26,437,784 (GRCm39)	nonsense	probably null
R4879:Dnah12	UTSW	14	26,439,201 (GRCm39)	critical splice donor site	probably null
R4893:Dnah12	UTSW	14	26,431,325 (GRCm39)	missense	possibly damaging	0.66
R4915:Dnah12	UTSW	14	26,455,725 (GRCm39)	missense	probably damaging	1.00
R4927:Dnah12	UTSW	14	26,583,762 (GRCm39)	nonsense	probably null
R4939:Dnah12	UTSW	14	26,613,481 (GRCm39)	missense	probably damaging	1.00
R4962:Dnah12	UTSW	14	26,437,855 (GRCm39)	missense	probably benign	0.00
R5011:Dnah12	UTSW	14	26,431,326 (GRCm39)	missense	probably benign	0.03
R5013:Dnah12	UTSW	14	26,431,326 (GRCm39)	missense	probably benign	0.03
R5043:Dnah12	UTSW	14	26,606,147 (GRCm39)	missense	probably damaging	1.00
R5049:Dnah12	UTSW	14	26,456,852 (GRCm39)	missense	probably benign	0.09
R5122:Dnah12	UTSW	14	26,439,155 (GRCm39)	missense	probably benign	0.00
R5135:Dnah12	UTSW	14	26,492,434 (GRCm39)	missense	probably damaging	0.99
R5149:Dnah12	UTSW	14	26,572,883 (GRCm39)	nonsense	probably null
R5154:Dnah12	UTSW	14	26,571,320 (GRCm39)	missense	probably benign	0.12
R5206:Dnah12	UTSW	14	26,491,942 (GRCm39)	missense	probably damaging	1.00
R5307:Dnah12	UTSW	14	26,414,641 (GRCm39)	missense	possibly damaging	0.49
R5330:Dnah12	UTSW	14	26,495,787 (GRCm39)	missense	probably damaging	1.00
R5335:Dnah12	UTSW	14	26,601,695 (GRCm39)	missense	probably damaging	1.00
R5339:Dnah12	UTSW	14	26,536,494 (GRCm39)	missense	possibly damaging	0.83
R5354:Dnah12	UTSW	14	26,496,299 (GRCm39)	splice site	probably null
R5389:Dnah12	UTSW	14	26,456,904 (GRCm39)	missense	probably damaging	1.00
R5434:Dnah12	UTSW	14	26,581,256 (GRCm39)	missense	probably damaging	1.00
R5466:Dnah12	UTSW	14	26,493,007 (GRCm39)	missense	probably damaging	1.00
R5655:Dnah12	UTSW	14	26,431,424 (GRCm39)	missense	probably benign	0.01
R5681:Dnah12	UTSW	14	26,537,452 (GRCm39)	missense	probably benign	0.32
R5824:Dnah12	UTSW	14	26,492,475 (GRCm39)	critical splice donor site	probably null
R5863:Dnah12	UTSW	14	26,576,878 (GRCm39)	missense	probably damaging	1.00
R5890:Dnah12	UTSW	14	26,428,039 (GRCm39)	missense	probably benign	0.09
R5912:Dnah12	UTSW	14	26,491,965 (GRCm39)	nonsense	probably null
R5916:Dnah12	UTSW	14	26,428,073 (GRCm39)	missense	possibly damaging	0.92
R5941:Dnah12	UTSW	14	26,428,022 (GRCm39)	missense	probably benign	0.00
R5987:Dnah12	UTSW	14	26,608,828 (GRCm39)	missense	possibly damaging	0.54
R5992:Dnah12	UTSW	14	26,418,496 (GRCm39)	missense	probably benign	0.04
R6132:Dnah12	UTSW	14	26,439,066 (GRCm39)	missense	probably damaging	1.00
R6136:Dnah12	UTSW	14	26,597,227 (GRCm39)	missense	probably damaging	0.99
R6158:Dnah12	UTSW	14	26,495,642 (GRCm39)	missense	possibly damaging	0.95
R6183:Dnah12	UTSW	14	26,583,726 (GRCm39)	missense	probably damaging	1.00
R6191:Dnah12	UTSW	14	26,431,412 (GRCm39)	missense	probably benign	0.03
R6235:Dnah12	UTSW	14	26,576,761 (GRCm39)	missense	probably damaging	1.00
R6277:Dnah12	UTSW	14	26,492,439 (GRCm39)	missense	probably damaging	1.00
R6332:Dnah12	UTSW	14	26,439,129 (GRCm39)	missense	probably damaging	0.99
R6334:Dnah12	UTSW	14	26,427,989 (GRCm39)	missense	possibly damaging	0.51
R6443:Dnah12	UTSW	14	26,600,008 (GRCm39)	missense	probably benign	0.06
R6480:Dnah12	UTSW	14	26,594,412 (GRCm39)	missense	probably damaging	1.00
R6530:Dnah12	UTSW	14	26,456,865 (GRCm39)	missense	probably damaging	1.00
R6678:Dnah12	UTSW	14	26,456,847 (GRCm39)	missense	probably damaging	1.00
R6709:Dnah12	UTSW	14	26,594,706 (GRCm39)	missense	probably damaging	1.00
R6724:Dnah12	UTSW	14	26,518,180 (GRCm39)	missense	probably benign	0.02
R6745:Dnah12	UTSW	14	26,428,383 (GRCm39)	missense	probably damaging	0.99
R6788:Dnah12	UTSW	14	26,523,470 (GRCm39)	missense	probably damaging	0.99
R6894:Dnah12	UTSW	14	26,456,904 (GRCm39)	missense	probably damaging	1.00
R6912:Dnah12	UTSW	14	26,600,036 (GRCm39)	missense	probably damaging	1.00
R6982:Dnah12	UTSW	14	26,521,033 (GRCm39)	splice site	probably null
R7001:Dnah12	UTSW	14	26,601,681 (GRCm39)	missense	probably damaging	0.99
R7002:Dnah12	UTSW	14	26,598,955 (GRCm39)	missense	probably damaging	1.00
R7017:Dnah12	UTSW	14	26,456,835 (GRCm39)	missense	probably benign
R7107:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7108:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7121:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7122:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7135:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7135:Dnah12	UTSW	14	26,523,370 (GRCm39)	missense	probably damaging	0.99
R7150:Dnah12	UTSW	14	26,583,689 (GRCm39)	missense	probably damaging	0.99
R7201:Dnah12	UTSW	14	26,536,579 (GRCm39)	missense	probably benign	0.08
R7202:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7204:Dnah12	UTSW	14	26,503,442 (GRCm39)	missense	probably damaging	0.99
R7204:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7205:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7206:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7219:Dnah12	UTSW	14	26,576,837 (GRCm39)	missense	probably damaging	0.99
R7337:Dnah12	UTSW	14	26,488,534 (GRCm39)	splice site	probably null
R7339:Dnah12	UTSW	14	26,594,277 (GRCm39)	missense	probably benign
R7363:Dnah12	UTSW	14	26,445,766 (GRCm39)	missense	probably benign
R7426:Dnah12	UTSW	14	26,445,781 (GRCm39)	missense	probably benign	0.01
R7472:Dnah12	UTSW	14	26,578,592 (GRCm39)	missense	probably benign	0.01
R7579:Dnah12	UTSW	14	26,492,460 (GRCm39)	missense	probably benign	0.05
R7655:Dnah12	UTSW	14	26,581,273 (GRCm39)	missense	probably benign	0.21
R7656:Dnah12	UTSW	14	26,581,273 (GRCm39)	missense	probably benign	0.21
R7694:Dnah12	UTSW	14	26,503,337 (GRCm39)	missense	probably damaging	1.00
R7730:Dnah12	UTSW	14	26,507,890 (GRCm39)	missense	probably damaging	1.00
R7837:Dnah12	UTSW	14	26,518,176 (GRCm39)	missense	probably benign	0.01
R7855:Dnah12	UTSW	14	26,551,286 (GRCm39)	missense	probably benign	0.14
R7870:Dnah12	UTSW	14	26,578,486 (GRCm39)	missense	probably benign	0.00
R7920:Dnah12	UTSW	14	26,578,499 (GRCm39)	missense	possibly damaging	0.58
R7933:Dnah12	UTSW	14	26,488,072 (GRCm39)	missense	probably benign	0.00
R7956:Dnah12	UTSW	14	26,430,427 (GRCm39)	missense	probably damaging	0.96
R8192:Dnah12	UTSW	14	26,428,036 (GRCm39)	missense	probably benign
R8263:Dnah12	UTSW	14	26,613,421 (GRCm39)	missense	noncoding transcript
R8287:Dnah12	UTSW	14	26,534,560 (GRCm39)	missense	probably benign
R8336:Dnah12	UTSW	14	26,432,220 (GRCm39)	missense	probably benign	0.01
R8362:Dnah12	UTSW	14	26,576,788 (GRCm39)	missense	probably damaging	1.00
R8392:Dnah12	UTSW	14	26,607,869 (GRCm39)	missense	probably benign
R8458:Dnah12	UTSW	14	26,548,849 (GRCm39)	critical splice acceptor site	probably null
R8481:Dnah12	UTSW	14	26,575,753 (GRCm39)	missense	probably benign	0.02
R8551:Dnah12	UTSW	14	26,496,227 (GRCm39)	missense	probably damaging	0.97
R8669:Dnah12	UTSW	14	26,552,582 (GRCm39)	splice site	probably benign
R8698:Dnah12	UTSW	14	26,428,418 (GRCm39)	missense	probably benign	0.02
R8709:Dnah12	UTSW	14	26,414,757 (GRCm39)	missense	probably benign	0.00
R8778:Dnah12	UTSW	14	26,455,718 (GRCm39)	missense	probably benign	0.29
R9049:Dnah12	UTSW	14	26,443,275 (GRCm39)	missense	probably benign	0.00
R9087:Dnah12	UTSW	14	26,546,503 (GRCm39)	missense	probably damaging	1.00
R9099:Dnah12	UTSW	14	26,492,325 (GRCm39)	missense	probably benign	0.31
R9153:Dnah12	UTSW	14	26,536,569 (GRCm39)	missense	probably damaging	1.00
R9177:Dnah12	UTSW	14	26,571,255 (GRCm39)	missense	possibly damaging	0.84
R9214:Dnah12	UTSW	14	26,445,060 (GRCm39)	missense	probably benign	0.02
R9268:Dnah12	UTSW	14	26,571,255 (GRCm39)	missense	possibly damaging	0.84
R9274:Dnah12	UTSW	14	26,537,374 (GRCm39)	missense	probably benign	0.00
R9293:Dnah12	UTSW	14	26,495,016 (GRCm39)	missense	probably benign
R9322:Dnah12	UTSW	14	26,492,934 (GRCm39)	missense	possibly damaging	0.75
R9353:Dnah12	UTSW	14	26,578,507 (GRCm39)	missense	probably damaging	1.00
R9506:Dnah12	UTSW	14	26,514,168 (GRCm39)	missense	probably benign	0.00
R9518:Dnah12	UTSW	14	26,495,713 (GRCm39)	missense	probably damaging	1.00
R9524:Dnah12	UTSW	14	26,572,494 (GRCm39)	missense	probably null	0.91
R9562:Dnah12	UTSW	14	26,597,281 (GRCm39)	missense	possibly damaging	0.58
R9565:Dnah12	UTSW	14	26,597,281 (GRCm39)	missense	possibly damaging	0.58
R9573:Dnah12	UTSW	14	26,414,619 (GRCm39)	missense	probably benign
R9581:Dnah12	UTSW	14	26,491,985 (GRCm39)	missense	probably damaging	1.00
R9689:Dnah12	UTSW	14	26,590,871 (GRCm39)	missense	probably null	1.00
R9727:Dnah12	UTSW	14	26,523,510 (GRCm39)	nonsense	probably null
V7580:Dnah12	UTSW	14	26,495,050 (GRCm39)	missense	possibly damaging	0.95
V7581:Dnah12	UTSW	14	26,495,050 (GRCm39)	missense	possibly damaging	0.95
X0018:Dnah12	UTSW	14	26,536,437 (GRCm39)	missense	probably damaging	1.00
X0027:Dnah12	UTSW	14	26,538,245 (GRCm39)	missense	probably damaging	1.00
X0065:Dnah12	UTSW	14	26,536,602 (GRCm39)	missense	possibly damaging	0.93
Z1177:Dnah12	UTSW	14	26,597,172 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GAATTCAGGTTAAGGGGCTCG -3'
(R):5'- CCGATCTTCATCATTAATAAGGCG -3'

Sequencing Primer
(F):5'- AGGGGCTCGTAAGTTCATTCAAC -3'
(R):5'- GGCGATCATAAAACACACGG -3'

Posted On

2019-06-26