Incidental Mutation 'R7203:Ly75'
| ID |
560744 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ly75
|
| Ensembl Gene |
ENSMUSG00000026980 |
| Gene Name |
lymphocyte antigen 75 |
| Synonyms |
DEC-205, CD205 |
| MMRRC Submission |
045281-MU
|
| Accession Numbers |
Genbank: NM_013825
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7203 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
60292103-60383303 bp(-) (GRCm38) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
G to A
at 60323852 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Stop codon
at position 1084
(R1084*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000028362
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028362]
[ENSMUST00000112533]
|
| AlphaFold |
Q60767 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000028362
AA Change: R1084*
|
| SMART Domains |
Protein: ENSMUSP00000028362
Gene: ENSMUSG00000026980
AA Change: R1084*
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000112533
AA Change: R1084*
|
| SMART Domains |
Protein: ENSMUSP00000108152
Gene: ENSMUSG00000026980
AA Change: R1084*
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
RICIN
|
33 |
146 |
2.63e-17 |
SMART |
|
FN2
|
162 |
209 |
1.22e-23 |
SMART |
|
CLECT
|
216 |
341 |
7.36e-32 |
SMART |
|
CLECT
|
361 |
486 |
9.28e-29 |
SMART |
|
CLECT
|
501 |
624 |
1.11e-17 |
SMART |
|
CLECT
|
643 |
791 |
1.93e-26 |
SMART |
|
CLECT
|
811 |
932 |
7.94e-2 |
SMART |
|
CLECT
|
952 |
1091 |
5.81e-21 |
SMART |
|
CLECT
|
1104 |
1222 |
1.04e-22 |
SMART |
|
CLECT
|
1240 |
1382 |
3.48e-10 |
SMART |
|
CLECT
|
1395 |
1513 |
9.59e-22 |
SMART |
|
CLECT
|
1530 |
1661 |
7.79e-22 |
SMART |
|
transmembrane domain
|
1670 |
1692 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
100% (108/108) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele display abnormalities in CD8-positive T cell morphology and cytotoxic T cell physiology. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(7) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(5)
|
| Other mutations in this stock |
Total: 108 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930544G11Rik |
T |
C |
6: 65,953,333 (GRCm38) |
V184A |
probably benign |
Het |
| 4932415D10Rik |
G |
A |
10: 82,293,414 (GRCm38) |
T1254I |
probably benign |
Het |
| Aars2 |
A |
G |
17: 45,516,571 (GRCm38) |
Y513C |
probably damaging |
Het |
| Ackr2 |
G |
A |
9: 121,908,967 (GRCm38) |
C136Y |
probably damaging |
Het |
| Aldh1l1 |
A |
G |
6: 90,570,800 (GRCm38) |
K414R |
probably benign |
Het |
| Arl9 |
A |
G |
5: 77,007,271 (GRCm38) |
Y83C |
possibly damaging |
Het |
| Atp10a |
G |
T |
7: 58,786,473 (GRCm38) |
R337L |
probably benign |
Het |
| Atp6v1g3 |
A |
T |
1: 138,287,800 (GRCm38) |
Q66L |
probably damaging |
Het |
| Atp7b |
A |
T |
8: 21,997,335 (GRCm38) |
N1321K |
probably damaging |
Het |
| Axdnd1 |
A |
T |
1: 156,382,389 (GRCm38) |
M437K |
probably damaging |
Het |
| Bap1 |
C |
A |
14: 31,254,169 (GRCm38) |
P147Q |
probably damaging |
Het |
| Bicd1 |
C |
T |
6: 149,512,905 (GRCm38) |
T372I |
possibly damaging |
Het |
| Brix1 |
T |
C |
15: 10,483,292 (GRCm38) |
|
probably null |
Het |
| Btrc |
A |
G |
19: 45,513,528 (GRCm38) |
|
probably null |
Het |
| C130050O18Rik |
A |
C |
5: 139,414,374 (GRCm38) |
I61L |
probably benign |
Het |
| Cfap161 |
A |
G |
7: 83,776,050 (GRCm38) |
S278P |
probably damaging |
Het |
| Cgnl1 |
T |
C |
9: 71,724,533 (GRCm38) |
D512G |
possibly damaging |
Het |
| Chat |
T |
C |
14: 32,419,057 (GRCm38) |
D461G |
probably damaging |
Het |
| Chl1 |
T |
A |
6: 103,691,674 (GRCm38) |
V456D |
probably benign |
Het |
| Cib1 |
T |
C |
7: 80,232,372 (GRCm38) |
T20A |
possibly damaging |
Het |
| Cubn |
T |
G |
2: 13,351,003 (GRCm38) |
H1806P |
probably benign |
Het |
| Dapk1 |
T |
A |
13: 60,696,335 (GRCm38) |
V56E |
possibly damaging |
Het |
| Dennd4a |
A |
G |
9: 64,896,474 (GRCm38) |
N1032D |
probably benign |
Het |
| Dlg5 |
T |
A |
14: 24,138,655 (GRCm38) |
E1756V |
probably damaging |
Het |
| Dnah1 |
T |
C |
14: 31,274,382 (GRCm38) |
T2666A |
probably benign |
Het |
| Dnah11 |
A |
T |
12: 118,045,522 (GRCm38) |
I2135N |
possibly damaging |
Het |
| Dnah6 |
T |
A |
6: 73,173,545 (GRCm38) |
E745V |
probably benign |
Het |
| Dock8 |
A |
T |
19: 25,181,563 (GRCm38) |
N1695I |
probably damaging |
Het |
| Esf1 |
C |
T |
2: 140,164,219 (GRCm38) |
R336Q |
possibly damaging |
Het |
| Fam161a |
A |
G |
11: 23,021,664 (GRCm38) |
|
probably null |
Het |
| Fam89a |
T |
C |
8: 124,751,679 (GRCm38) |
E44G |
possibly damaging |
Het |
| Fndc3b |
A |
T |
3: 27,456,485 (GRCm38) |
D829E |
probably benign |
Het |
| Fxr1 |
C |
T |
3: 34,046,540 (GRCm38) |
T125I |
possibly damaging |
Het |
| Gfer |
T |
C |
17: 24,695,862 (GRCm38) |
D69G |
probably damaging |
Het |
| Gm16486 |
A |
T |
8: 70,716,948 (GRCm38) |
E1229V |
probably benign |
Het |
| Gm2000 |
A |
T |
1: 156,366,087 (GRCm38) |
I4F |
probably damaging |
Het |
| Gpatch2l |
T |
A |
12: 86,288,937 (GRCm38) |
S471T |
probably benign |
Het |
| Grm7 |
T |
G |
6: 111,358,569 (GRCm38) |
I647S |
possibly damaging |
Het |
| Gsn |
A |
G |
2: 35,298,795 (GRCm38) |
I447V |
probably benign |
Het |
| H2al2c |
C |
T |
Y: 2,599,234 (GRCm38) |
L46F |
possibly damaging |
Het |
| Hao2 |
A |
C |
3: 98,877,282 (GRCm38) |
|
probably null |
Het |
| Ifitm10 |
T |
C |
7: 142,328,568 (GRCm38) |
E155G |
probably benign |
Het |
| Igkv8-16 |
C |
A |
6: 70,386,810 (GRCm38) |
W76L |
probably benign |
Het |
| Igsf21 |
A |
T |
4: 140,107,337 (GRCm38) |
F75I |
possibly damaging |
Het |
| Ints14 |
T |
A |
9: 64,964,419 (GRCm38) |
M13K |
probably damaging |
Het |
| Ipmk |
A |
T |
10: 71,363,468 (GRCm38) |
D53V |
possibly damaging |
Het |
| Itga8 |
A |
G |
2: 12,230,095 (GRCm38) |
F451L |
possibly damaging |
Het |
| Jup |
A |
G |
11: 100,381,734 (GRCm38) |
F284S |
probably damaging |
Het |
| Kctd5 |
T |
C |
17: 24,073,235 (GRCm38) |
D65G |
probably benign |
Het |
| Klrc1 |
A |
T |
6: 129,677,221 (GRCm38) |
S148T |
probably benign |
Het |
| Kmt5b |
A |
G |
19: 3,814,147 (GRCm38) |
K404E |
probably damaging |
Het |
| Krt9 |
A |
C |
11: 100,190,791 (GRCm38) |
M304R |
probably damaging |
Het |
| Krtap5-1 |
A |
T |
7: 142,296,562 (GRCm38) |
S143T |
unknown |
Het |
| Kyat3 |
A |
G |
3: 142,720,401 (GRCm38) |
N68D |
probably damaging |
Het |
| Kynu |
A |
G |
2: 43,681,353 (GRCm38) |
D427G |
probably damaging |
Het |
| Leo1 |
A |
G |
9: 75,445,996 (GRCm38) |
|
probably null |
Het |
| Loxhd1 |
A |
G |
18: 77,414,196 (GRCm38) |
D1737G |
probably damaging |
Het |
| Lpo |
C |
A |
11: 87,809,251 (GRCm38) |
L521F |
possibly damaging |
Het |
| Lrrk1 |
A |
G |
7: 66,270,825 (GRCm38) |
S1477P |
probably damaging |
Het |
| Lrrtm1 |
C |
A |
6: 77,243,601 (GRCm38) |
L14M |
probably damaging |
Het |
| Mcf2l |
A |
G |
8: 13,010,456 (GRCm38) |
D764G |
probably benign |
Het |
| Mrgprd |
A |
T |
7: 145,322,349 (GRCm38) |
D319V |
probably benign |
Het |
| Mut |
A |
T |
17: 40,938,673 (GRCm38) |
M180L |
probably benign |
Het |
| Myom3 |
T |
C |
4: 135,795,179 (GRCm38) |
L897P |
possibly damaging |
Het |
| Ncapd2 |
A |
T |
6: 125,184,328 (GRCm38) |
M247K |
possibly damaging |
Het |
| Nlrp2 |
T |
C |
7: 5,317,534 (GRCm38) |
D868G |
probably damaging |
Het |
| Npy6r |
A |
G |
18: 44,275,932 (GRCm38) |
N140S |
probably damaging |
Het |
| Nsmce4a |
T |
C |
7: 130,539,872 (GRCm38) |
K196E |
probably benign |
Het |
| Nup88 |
T |
C |
11: 70,945,254 (GRCm38) |
K532R |
probably benign |
Het |
| Olfr424 |
T |
A |
1: 174,137,114 (GRCm38) |
Y123* |
probably null |
Het |
| Olfr947-ps1 |
A |
T |
9: 39,289,293 (GRCm38) |
I199N |
unknown |
Het |
| Olfr974 |
T |
A |
9: 39,942,509 (GRCm38) |
V83E |
probably benign |
Het |
| Pbxip1 |
A |
T |
3: 89,447,428 (GRCm38) |
D418V |
possibly damaging |
Het |
| Pde2a |
C |
A |
7: 101,509,944 (GRCm38) |
R761S |
possibly damaging |
Het |
| Phf10 |
A |
T |
17: 14,946,313 (GRCm38) |
C432S |
probably damaging |
Het |
| Pitpnm2 |
T |
C |
5: 124,121,459 (GRCm38) |
D1271G |
probably damaging |
Het |
| Plin1 |
A |
T |
7: 79,723,444 (GRCm38) |
L259Q |
probably damaging |
Het |
| Pmpca |
G |
C |
2: 26,395,034 (GRCm38) |
E424Q |
possibly damaging |
Het |
| Pou6f2 |
T |
A |
13: 18,239,794 (GRCm38) |
Q132L |
unknown |
Het |
| Ppa2 |
A |
T |
3: 133,330,438 (GRCm38) |
N118Y |
possibly damaging |
Het |
| Prickle2 |
T |
C |
6: 92,410,978 (GRCm38) |
E537G |
possibly damaging |
Het |
| Prl3d1 |
A |
G |
13: 27,098,701 (GRCm38) |
I141V |
possibly damaging |
Het |
| Prl8a1 |
A |
T |
13: 27,574,189 (GRCm38) |
V179D |
probably damaging |
Het |
| Prr14l |
A |
G |
5: 32,827,145 (GRCm38) |
F1669L |
probably benign |
Het |
| Prrg4 |
T |
A |
2: 104,839,442 (GRCm38) |
E110V |
possibly damaging |
Het |
| Rfx5 |
C |
A |
3: 94,958,876 (GRCm38) |
H495Q |
unknown |
Het |
| Rgl2 |
C |
T |
17: 33,933,429 (GRCm38) |
R367W |
probably damaging |
Het |
| Rpe65 |
A |
G |
3: 159,622,854 (GRCm38) |
Y433C |
probably damaging |
Het |
| Rtn4rl1 |
C |
T |
11: 75,265,750 (GRCm38) |
S336F |
possibly damaging |
Het |
| Scn2a |
A |
G |
2: 65,748,319 (GRCm38) |
D1446G |
probably benign |
Het |
| Sdk1 |
C |
A |
5: 142,046,176 (GRCm38) |
T1002K |
probably benign |
Het |
| Slc9b2 |
T |
C |
3: 135,330,661 (GRCm38) |
S409P |
probably benign |
Het |
| Sowahc |
A |
G |
10: 59,222,278 (GRCm38) |
T79A |
probably benign |
Het |
| Stk35 |
T |
A |
2: 129,801,593 (GRCm38) |
C166S |
probably benign |
Het |
| Tarbp2 |
A |
G |
15: 102,522,487 (GRCm38) |
H225R |
probably benign |
Het |
| Tdrd12 |
T |
A |
7: 35,489,223 (GRCm38) |
K530* |
probably null |
Het |
| Terf2ip |
A |
G |
8: 112,017,986 (GRCm38) |
I312V |
probably benign |
Het |
| Tgfb1 |
T |
C |
7: 25,692,539 (GRCm38) |
|
probably null |
Het |
| Thbs2 |
T |
C |
17: 14,671,458 (GRCm38) |
D939G |
probably damaging |
Het |
| Ube4b |
A |
T |
4: 149,398,610 (GRCm38) |
I67K |
probably benign |
Het |
| Ubn1 |
G |
T |
16: 5,077,216 (GRCm38) |
V709F |
possibly damaging |
Het |
| Ugt2b5 |
T |
C |
5: 87,128,399 (GRCm38) |
K339E |
possibly damaging |
Het |
| Vax2 |
T |
C |
6: 83,737,900 (GRCm38) |
S266P |
probably damaging |
Het |
| Vmn2r108 |
A |
G |
17: 20,462,776 (GRCm38) |
I722T |
probably benign |
Het |
| Vmn2r95 |
A |
G |
17: 18,441,315 (GRCm38) |
K441R |
probably benign |
Het |
| Wapl |
C |
A |
14: 34,736,691 (GRCm38) |
D903E |
probably benign |
Het |
| Wee1 |
T |
A |
7: 110,134,794 (GRCm38) |
V442D |
probably benign |
Het |
| Zan |
T |
C |
5: 137,434,096 (GRCm38) |
N2313S |
unknown |
Het |
|
| Other mutations in Ly75 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00561:Ly75
|
APN |
2 |
60,376,077 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01072:Ly75
|
APN |
2 |
60,354,496 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01409:Ly75
|
APN |
2 |
60,321,692 (GRCm38) |
splice site |
probably null |
|
|
IGL01432:Ly75
|
APN |
2 |
60,376,007 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01626:Ly75
|
APN |
2 |
60,301,015 (GRCm38) |
missense |
probably benign |
0.13 |
|
IGL01690:Ly75
|
APN |
2 |
60,338,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01862:Ly75
|
APN |
2 |
60,299,172 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01982:Ly75
|
APN |
2 |
60,311,764 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02075:Ly75
|
APN |
2 |
60,352,356 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02338:Ly75
|
APN |
2 |
60,354,452 (GRCm38) |
missense |
probably benign |
0.04 |
|
IGL02364:Ly75
|
APN |
2 |
60,358,507 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02456:Ly75
|
APN |
2 |
60,293,781 (GRCm38) |
missense |
probably benign |
0.09 |
|
IGL02474:Ly75
|
APN |
2 |
60,383,182 (GRCm38) |
missense |
probably null |
1.00 |
|
IGL02608:Ly75
|
APN |
2 |
60,321,900 (GRCm38) |
missense |
probably benign |
0.41 |
|
IGL02986:Ly75
|
APN |
2 |
60,308,191 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03015:Ly75
|
APN |
2 |
60,376,160 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03049:Ly75
|
APN |
2 |
60,352,070 (GRCm38) |
missense |
probably damaging |
0.99 |
|
euphues
|
UTSW |
2 |
60,299,045 (GRCm38) |
critical splice donor site |
probably null |
|
|
four_score
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
lyly
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
Witty
|
UTSW |
2 |
60,354,500 (GRCm38) |
missense |
probably damaging |
1.00 |
|
D605:Ly75
|
UTSW |
2 |
60,352,352 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0046:Ly75
|
UTSW |
2 |
60,339,457 (GRCm38) |
intron |
probably benign |
|
|
R0055:Ly75
|
UTSW |
2 |
60,321,918 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0055:Ly75
|
UTSW |
2 |
60,321,918 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,321,819 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0071:Ly75
|
UTSW |
2 |
60,321,819 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0285:Ly75
|
UTSW |
2 |
60,318,319 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0387:Ly75
|
UTSW |
2 |
60,306,404 (GRCm38) |
missense |
probably benign |
0.20 |
|
R0492:Ly75
|
UTSW |
2 |
60,308,276 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0688:Ly75
|
UTSW |
2 |
60,316,221 (GRCm38) |
missense |
probably benign |
0.41 |
|
R1367:Ly75
|
UTSW |
2 |
60,293,758 (GRCm38) |
splice site |
probably null |
|
|
R1463:Ly75
|
UTSW |
2 |
60,368,757 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1581:Ly75
|
UTSW |
2 |
60,327,893 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1663:Ly75
|
UTSW |
2 |
60,314,234 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1818:Ly75
|
UTSW |
2 |
60,311,777 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1881:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2244:Ly75
|
UTSW |
2 |
60,349,913 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2905:Ly75
|
UTSW |
2 |
60,334,554 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3967:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R3968:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R4039:Ly75
|
UTSW |
2 |
60,352,995 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4406:Ly75
|
UTSW |
2 |
60,354,550 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4526:Ly75
|
UTSW |
2 |
60,330,773 (GRCm38) |
missense |
probably benign |
0.09 |
|
R4647:Ly75
|
UTSW |
2 |
60,308,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4795:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4796:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4962:Ly75
|
UTSW |
2 |
60,352,125 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4979:Ly75
|
UTSW |
2 |
60,375,894 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5072:Ly75
|
UTSW |
2 |
60,375,963 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5288:Ly75
|
UTSW |
2 |
60,303,641 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5373:Ly75
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R5374:Ly75
|
UTSW |
2 |
60,311,771 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R5384:Ly75
|
UTSW |
2 |
60,334,487 (GRCm38) |
nonsense |
probably null |
|
|
R5385:Ly75
|
UTSW |
2 |
60,303,641 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5395:Ly75
|
UTSW |
2 |
60,365,111 (GRCm38) |
missense |
probably benign |
0.41 |
|
R5531:Ly75
|
UTSW |
2 |
60,365,145 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5662:Ly75
|
UTSW |
2 |
60,352,381 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5667:Ly75
|
UTSW |
2 |
60,308,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5668:Ly75
|
UTSW |
2 |
60,354,500 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5671:Ly75
|
UTSW |
2 |
60,308,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5677:Ly75
|
UTSW |
2 |
60,299,082 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5764:Ly75
|
UTSW |
2 |
60,318,439 (GRCm38) |
missense |
probably benign |
|
|
R5896:Ly75
|
UTSW |
2 |
60,383,146 (GRCm38) |
missense |
probably benign |
|
|
R6025:Ly75
|
UTSW |
2 |
60,375,962 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6113:Ly75
|
UTSW |
2 |
60,368,873 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6448:Ly75
|
UTSW |
2 |
60,299,045 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6601:Ly75
|
UTSW |
2 |
60,318,376 (GRCm38) |
missense |
probably benign |
0.11 |
|
R6745:Ly75
|
UTSW |
2 |
60,308,179 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6955:Ly75
|
UTSW |
2 |
60,327,873 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R6960:Ly75
|
UTSW |
2 |
60,306,405 (GRCm38) |
missense |
probably benign |
|
|
R7100:Ly75
|
UTSW |
2 |
60,306,434 (GRCm38) |
missense |
probably benign |
|
|
R7110:Ly75
|
UTSW |
2 |
60,376,184 (GRCm38) |
missense |
probably benign |
0.31 |
|
R7291:Ly75
|
UTSW |
2 |
60,329,993 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7308:Ly75
|
UTSW |
2 |
60,334,515 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7447:Ly75
|
UTSW |
2 |
60,334,474 (GRCm38) |
nonsense |
probably null |
|
|
R7512:Ly75
|
UTSW |
2 |
60,334,563 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7595:Ly75
|
UTSW |
2 |
60,293,827 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7976:Ly75
|
UTSW |
2 |
60,365,088 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8005:Ly75
|
UTSW |
2 |
60,332,934 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8171:Ly75
|
UTSW |
2 |
60,314,228 (GRCm38) |
missense |
possibly damaging |
0.51 |
|
R8392:Ly75
|
UTSW |
2 |
60,349,940 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8705:Ly75
|
UTSW |
2 |
60,318,385 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8714:Ly75
|
UTSW |
2 |
60,334,485 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8798:Ly75
|
UTSW |
2 |
60,323,926 (GRCm38) |
missense |
probably benign |
0.32 |
|
R8799:Ly75
|
UTSW |
2 |
60,348,441 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8834:Ly75
|
UTSW |
2 |
60,331,089 (GRCm38) |
missense |
probably benign |
|
|
R8990:Ly75
|
UTSW |
2 |
60,358,559 (GRCm38) |
missense |
probably benign |
0.10 |
|
R9015:Ly75
|
UTSW |
2 |
60,316,098 (GRCm38) |
missense |
probably benign |
|
|
R9547:Ly75
|
UTSW |
2 |
60,330,725 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9628:Ly75
|
UTSW |
2 |
60,327,941 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9659:Ly75
|
UTSW |
2 |
60,338,321 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9660:Ly75
|
UTSW |
2 |
60,323,840 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9747:Ly75
|
UTSW |
2 |
60,306,328 (GRCm38) |
critical splice donor site |
probably null |
|
|
X0025:Ly75
|
UTSW |
2 |
60,354,475 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1177:Ly75
|
UTSW |
2 |
60,352,133 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
Z1177:Ly75
|
UTSW |
2 |
60,350,004 (GRCm38) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AATCCCATGTATAGACCTGGCC -3'
(R):5'- TAGGTCTCAAATGTCCGTCATG -3'
Sequencing Primer
(F):5'- ATGTATAGACCTGGCCAGTGCTC -3'
(R):5'- GGTCTCAAATGTCCGTCATGTTTCTG -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation