Mutagenetix > Incidental Mutation

Incidental Mutation 'R7211:Nbea'

561045

Institutional Source

Beutler Lab

Gene Symbol

Nbea

Ensembl Gene

ENSMUSG00000027799

Gene Name

neurobeachin

Synonyms

MMRRC Submission

045339-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R7211 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

55625195-56183701 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 56004901 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Isoleucine at position 1155 (N1155I)

Ref Sequence

ENSEMBL: ENSMUSP00000029374 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000029374]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000029374
AA Change: N1155I

PolyPhen 2 Score 0.049 (Sensitivity: 0.94; Specificity: 0.83)

SMART Domains

Protein: ENSMUSP00000029374
Gene: ENSMUSG00000027799
AA Change: N1155I

Domain	Start	End	E-Value	Type
low complexity region	19	40	N/A	INTRINSIC
Pfam:Laminin_G_3	228	393	2.8e-13	PFAM
Pfam:DUF4704	462	733	4e-113	PFAM
low complexity region	792	802	N/A	INTRINSIC
low complexity region	964	969	N/A	INTRINSIC
low complexity region	1781	1790	N/A	INTRINSIC
low complexity region	1791	1807	N/A	INTRINSIC
low complexity region	1835	1845	N/A	INTRINSIC
Pfam:DUF1088	1956	2122	3.5e-91	PFAM
Pfam:PH_BEACH	2148	2245	2.6e-32	PFAM
Beach	2276	2553	1.3e-205	SMART
WD40	2659	2696	2.12e2	SMART
WD40	2699	2742	2.22e0	SMART
WD40	2759	2798	9.21e0	SMART
WD40	2842	2880	2.88e-1	SMART
WD40	2883	2922	8.91e-1	SMART

Meta Mutation Damage Score

0.0598

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.6%

Validation Efficiency

99% (84/85)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. This gene and its expression are frequently disrupted in patients with multiple myeloma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants may exist, but their full-length nature has not been determined.[provided by RefSeq, Feb 2011]
PHENOTYPE: Mice homozygous for a gene trapped allele or transgene insertion die shortly after birth, are cyanotic, and exhibit no response to tactile stimuli, no spontaneous movement, and impaired CNS synaptic transmission. [provided by MGI curators]

Allele List at MGI

All alleles(4) : Gene trapped(3) Transgenic(1)

Other mutations in this stock

Total: 82 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
a	T	A	2: 155,045,779 (GRCm38)	V53E	probably damaging	Het
A1cf	A	G	19: 31,927,141 (GRCm38)	Y268C	probably benign	Het
Adam34l	T	A	8: 43,625,877 (GRCm38)	S437C	probably damaging	Het
Adamts13	C	T	2: 26,989,298 (GRCm38)	T621I	probably benign	Het
Akr1b7	A	T	6: 34,421,114 (GRCm38)	N293Y	probably benign	Het
Angpt2	T	A	8: 18,741,131 (GRCm38)	T50S	probably benign	Het
Anks1b	C	A	10: 90,511,070 (GRCm38)	A744D	possibly damaging	Het
Aqr	A	G	2: 114,134,723 (GRCm38)	V587A	probably benign	Het
Atm	A	G	9: 53,488,560 (GRCm38)	V1540A	probably benign	Het
Brd10	A	G	19: 29,786,312 (GRCm38)	F121S		Het
C4b	A	G	17: 34,735,534 (GRCm38)	V887A	possibly damaging	Het
Cd200r1	A	G	16: 44,788,757 (GRCm38)	T26A	probably benign	Het
Ciao1	A	G	2: 127,247,008 (GRCm38)		probably null	Het
Clba1	T	A	12: 112,811,012 (GRCm38)		probably null	Het
Clca3a2	A	G	3: 144,814,014 (GRCm38)	C200R	probably benign	Het
Col6a5	T	A	9: 105,928,164 (GRCm38)	Q1181L	unknown	Het
Copb2	T	A	9: 98,574,145 (GRCm38)	I244N	probably damaging	Het
Cpb2	A	G	14: 75,274,990 (GRCm38)	Y281C	probably damaging	Het
Disp3	C	A	4: 148,241,522 (GRCm38)	V1260F	probably damaging	Het
Dnajc2	C	T	5: 21,776,779 (GRCm38)	R123Q	probably damaging	Het
Dpysl2	T	C	14: 66,829,976 (GRCm38)	N162S	probably damaging	Het
Dsp	T	A	13: 38,188,535 (GRCm38)		probably null	Het
Edc4	T	A	8: 105,886,309 (GRCm38)		probably null	Het
Epm2a	T	C	10: 11,343,675 (GRCm38)	Y69H	probably benign	Het
Frzb	C	A	2: 80,418,325 (GRCm38)	E262*	probably null	Het
Gaa	T	C	11: 119,284,204 (GRCm38)	V877A	possibly damaging	Het
Gm11639	G	T	11: 104,724,609 (GRCm38)		probably null	Het
Gm11639	C	A	11: 104,710,713 (GRCm38)	A284D	probably benign	Het
Gpnmb	T	C	6: 49,052,015 (GRCm38)	I489T	possibly damaging	Het
Gpr31b	T	C	17: 13,052,217 (GRCm38)	T22A	probably benign	Het
Gys1	T	A	7: 45,448,260 (GRCm38)	F477Y	possibly damaging	Het
Hoxc11	A	C	15: 102,955,052 (GRCm38)	E176A	possibly damaging	Het
Kcnk13	T	A	12: 100,061,817 (GRCm38)	F384I	probably damaging	Het
Ky	A	G	9: 102,509,150 (GRCm38)	E59G	probably benign	Het
Lama4	T	A	10: 39,005,495 (GRCm38)	D93E	probably damaging	Het
Lrrc23	A	T	6: 124,778,189 (GRCm38)	N128K	probably benign	Het
Lrrc71	G	T	3: 87,743,326 (GRCm38)	Q210K	possibly damaging	Het
Map1a	G	A	2: 121,304,643 (GRCm38)	R1980H	probably benign	Het
Med15	T	C	16: 17,698,113 (GRCm38)	D15G	unknown	Het
Mfng	A	T	15: 78,773,068 (GRCm38)	S69T	probably benign	Het
Muc16	T	G	9: 18,498,570 (GRCm38)	S181R	probably damaging	Het
Mug1	A	T	6: 121,880,539 (GRCm38)	Q1074L	possibly damaging	Het
Myorg	A	G	4: 41,498,028 (GRCm38)	I534T	probably damaging	Het
Nbeal1	T	G	1: 60,200,951 (GRCm38)	L159V	probably damaging	Het
Nudt1	C	A	5: 140,337,647 (GRCm38)	P118Q	possibly damaging	Het
Or2q1	A	T	6: 42,818,016 (GRCm38)	T182S	probably benign	Het
Or8g37	A	C	9: 39,819,858 (GRCm38)	Q73P	possibly damaging	Het
Pcdhga6	T	A	18: 37,709,120 (GRCm38)	V631D	probably benign	Het
Pcna	A	C	2: 132,249,872 (GRCm38)	V203G	probably damaging	Het
Pgf	G	T	12: 85,175,775 (GRCm38)	N33K	probably benign	Het
Pgm1	T	C	5: 64,105,850 (GRCm38)	L280P	probably damaging	Het
Plcg1	G	A	2: 160,731,874 (GRCm38)	A20T	probably benign	Het
Pou2af2	G	T	9: 51,290,433 (GRCm38)	Q108K	probably damaging	Het
Prdx5	G	T	19: 6,907,590 (GRCm38)	D126E	probably damaging	Het
Prkag2	T	C	5: 24,995,298 (GRCm38)	T20A	probably benign	Het
Prr14l	T	A	5: 32,830,087 (GRCm38)	Q688L	probably damaging	Het
Pxdn	T	G	12: 29,984,904 (GRCm38)	D253E	possibly damaging	Het
Rbm18	A	T	2: 36,122,893 (GRCm38)	C53*	probably null	Het
Rprm	A	T	2: 54,085,258 (GRCm38)	L16Q	probably benign	Het
Saysd1	A	G	14: 20,077,508 (GRCm38)	F116S	probably damaging	Het
Scg3	A	G	9: 75,682,084 (GRCm38)	S96P	probably benign	Het
Scgb1b3	C	T	7: 31,375,653 (GRCm38)	L16F	unknown	Het
Sh3tc2	A	G	18: 61,989,403 (GRCm38)	T412A	probably benign	Het
Skint6	T	C	4: 113,238,369 (GRCm38)	N31S	probably benign	Het
Slc22a2	T	C	17: 12,586,883 (GRCm38)		probably null	Het
Slc8a2	C	T	7: 16,140,613 (GRCm38)	T262I	possibly damaging	Het
Smarcc1	A	T	9: 110,150,014 (GRCm38)	K188N	probably damaging	Het
Taf6	T	C	5: 138,178,826 (GRCm38)	T660A	possibly damaging	Het
Tbx2	C	T	11: 85,834,714 (GRCm38)	R164C	probably damaging	Het
Tec	T	C	5: 72,782,012 (GRCm38)	D220G	probably null	Het
Tfec	A	T	6: 16,867,465 (GRCm38)	W59R	probably damaging	Het
Tmtc2	G	T	10: 105,573,726 (GRCm38)	S8R	probably benign	Het
Tmtc3	A	T	10: 100,447,605 (GRCm38)	M696K	probably benign	Het
Trpc3	A	T	3: 36,640,733 (GRCm38)	S691T	possibly damaging	Het
Ttf2	A	T	3: 100,959,307 (GRCm38)	M503K	probably benign	Het
Ttll7	A	G	3: 146,913,276 (GRCm38)	H312R	probably damaging	Het
Ttn	T	C	2: 76,767,688 (GRCm38)	Y19627C	probably damaging	Het
Ugt2b35	T	C	5: 87,001,318 (GRCm38)	S143P	probably benign	Het
Usp53	A	G	3: 122,957,650 (GRCm38)	S253P	probably damaging	Het
Utp18	A	G	11: 93,885,380 (GRCm38)	V93A	probably benign	Het
Utrn	T	C	10: 12,401,335 (GRCm38)	N3413D	possibly damaging	Het
Zhx1	T	C	15: 58,053,251 (GRCm38)	D533G	possibly damaging	Het

Other mutations in Nbea

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00540:Nbea	APN	3	55,628,493 (GRCm38)	missense	probably damaging	1.00
IGL00541:Nbea	APN	3	55,968,089 (GRCm38)	missense	probably benign	0.02
IGL00584:Nbea	APN	3	56,082,448 (GRCm38)	missense	probably damaging	0.98
IGL00648:Nbea	APN	3	56,009,260 (GRCm38)	missense	probably damaging	0.98
IGL00785:Nbea	APN	3	55,955,393 (GRCm38)	missense	probably benign
IGL00899:Nbea	APN	3	55,642,845 (GRCm38)	missense	probably benign	0.32
IGL00955:Nbea	APN	3	56,005,472 (GRCm38)	missense	possibly damaging	0.45
IGL01296:Nbea	APN	3	56,031,536 (GRCm38)	missense	probably benign	0.04
IGL01299:Nbea	APN	3	55,690,894 (GRCm38)	missense	probably damaging	1.00
IGL01393:Nbea	APN	3	56,005,308 (GRCm38)	missense	probably benign	0.02
IGL01550:Nbea	APN	3	55,805,248 (GRCm38)	missense	possibly damaging	0.93
IGL02023:Nbea	APN	3	55,681,016 (GRCm38)	missense	probably damaging	1.00
IGL02034:Nbea	APN	3	55,968,156 (GRCm38)	missense	probably damaging	1.00
IGL02061:Nbea	APN	3	55,717,887 (GRCm38)	missense	possibly damaging	0.54
IGL02082:Nbea	APN	3	55,968,167 (GRCm38)	missense	possibly damaging	0.88
IGL02113:Nbea	APN	3	55,992,492 (GRCm38)	missense	probably benign
IGL02188:Nbea	APN	3	55,983,837 (GRCm38)	missense	probably benign	0.00
IGL02319:Nbea	APN	3	55,985,738 (GRCm38)	missense	probably damaging	1.00
IGL02406:Nbea	APN	3	56,086,266 (GRCm38)	missense	probably benign	0.02
IGL02494:Nbea	APN	3	55,805,351 (GRCm38)	missense	probably benign	0.02
IGL02550:Nbea	APN	3	56,019,414 (GRCm38)	missense	probably damaging	0.98
IGL02706:Nbea	APN	3	56,037,278 (GRCm38)	missense	probably damaging	1.00
IGL02718:Nbea	APN	3	55,632,062 (GRCm38)	nonsense	probably null
IGL02822:Nbea	APN	3	56,019,447 (GRCm38)	missense	possibly damaging	0.93
IGL02885:Nbea	APN	3	55,631,986 (GRCm38)	missense	probably benign	0.01
IGL03000:Nbea	APN	3	56,004,627 (GRCm38)	missense	possibly damaging	0.94
IGL03081:Nbea	APN	3	56,079,918 (GRCm38)	missense	probably damaging	1.00
IGL03091:Nbea	APN	3	56,085,304 (GRCm38)	missense	probably damaging	1.00
IGL03368:Nbea	APN	3	56,079,930 (GRCm38)	missense	probably damaging	0.98
Neches	UTSW	3	55,953,034 (GRCm38)	critical splice donor site	probably null
scotland	UTSW	3	55,626,908 (GRCm38)	missense	probably damaging	1.00
Wales	UTSW	3	56,091,119 (GRCm38)	missense	probably damaging	1.00
FR4340:Nbea	UTSW	3	56,009,212 (GRCm38)	critical splice donor site	probably benign
G4846:Nbea	UTSW	3	56,087,497 (GRCm38)	missense	probably damaging	0.98
IGL02835:Nbea	UTSW	3	55,717,869 (GRCm38)	missense	possibly damaging	0.88
LCD18:Nbea	UTSW	3	55,701,527 (GRCm38)	intron	probably benign
R0087:Nbea	UTSW	3	56,091,023 (GRCm38)	missense	possibly damaging	0.92
R0220:Nbea	UTSW	3	56,005,303 (GRCm38)	missense	probably benign	0.30
R0324:Nbea	UTSW	3	56,057,948 (GRCm38)	critical splice donor site	probably null
R0330:Nbea	UTSW	3	55,642,817 (GRCm38)	missense	probably benign	0.27
R0391:Nbea	UTSW	3	56,037,277 (GRCm38)	missense	probably damaging	1.00
R0394:Nbea	UTSW	3	56,029,907 (GRCm38)	missense	probably damaging	1.00
R0419:Nbea	UTSW	3	55,819,294 (GRCm38)	missense	probably benign	0.05
R0503:Nbea	UTSW	3	55,642,836 (GRCm38)	missense	possibly damaging	0.79
R0521:Nbea	UTSW	3	56,008,268 (GRCm38)	missense	probably damaging	1.00
R0595:Nbea	UTSW	3	55,628,496 (GRCm38)	missense	probably benign	0.18
R0894:Nbea	UTSW	3	56,009,340 (GRCm38)	missense	possibly damaging	0.89
R1072:Nbea	UTSW	3	56,086,196 (GRCm38)	missense	possibly damaging	0.94
R1125:Nbea	UTSW	3	55,857,006 (GRCm38)	nonsense	probably null
R1169:Nbea	UTSW	3	55,968,323 (GRCm38)	missense	probably benign	0.00
R1241:Nbea	UTSW	3	56,058,040 (GRCm38)	missense	probably damaging	1.00
R1269:Nbea	UTSW	3	56,004,781 (GRCm38)	missense	probably benign	0.05
R1406:Nbea	UTSW	3	56,037,281 (GRCm38)	missense	probably benign	0.00
R1406:Nbea	UTSW	3	56,037,281 (GRCm38)	missense	probably benign	0.00
R1457:Nbea	UTSW	3	56,085,327 (GRCm38)	missense	probably damaging	1.00
R1482:Nbea	UTSW	3	56,079,993 (GRCm38)	missense	probably damaging	1.00
R1483:Nbea	UTSW	3	56,002,790 (GRCm38)	missense	probably benign	0.25
R1502:Nbea	UTSW	3	56,004,889 (GRCm38)	missense	probably benign	0.03
R1544:Nbea	UTSW	3	56,058,827 (GRCm38)	missense	probably damaging	0.99
R1629:Nbea	UTSW	3	56,002,891 (GRCm38)	missense	possibly damaging	0.52
R1647:Nbea	UTSW	3	55,630,229 (GRCm38)	missense	probably damaging	0.97
R1663:Nbea	UTSW	3	55,645,986 (GRCm38)	missense	possibly damaging	0.95
R1722:Nbea	UTSW	3	55,665,695 (GRCm38)	missense	probably damaging	1.00
R1757:Nbea	UTSW	3	55,630,189 (GRCm38)	missense	possibly damaging	0.83
R1771:Nbea	UTSW	3	55,934,519 (GRCm38)	missense	probably benign	0.00
R1796:Nbea	UTSW	3	55,643,708 (GRCm38)	missense	possibly damaging	0.48
R1844:Nbea	UTSW	3	56,082,436 (GRCm38)	missense	probably damaging	0.97
R1872:Nbea	UTSW	3	55,642,889 (GRCm38)	missense	probably benign	0.12
R1938:Nbea	UTSW	3	56,085,322 (GRCm38)	missense	probably damaging	1.00
R1940:Nbea	UTSW	3	55,953,100 (GRCm38)	missense	possibly damaging	0.78
R2062:Nbea	UTSW	3	56,086,157 (GRCm38)	splice site	probably benign
R2066:Nbea	UTSW	3	55,968,146 (GRCm38)	missense	probably damaging	1.00
R2097:Nbea	UTSW	3	55,723,217 (GRCm38)	missense	probably damaging	0.96
R2181:Nbea	UTSW	3	56,029,939 (GRCm38)	missense	possibly damaging	0.92
R2274:Nbea	UTSW	3	55,988,085 (GRCm38)	splice site	probably null
R2345:Nbea	UTSW	3	56,085,279 (GRCm38)	missense	probably damaging	1.00
R2423:Nbea	UTSW	3	56,085,306 (GRCm38)	missense	probably damaging	1.00
R2434:Nbea	UTSW	3	55,647,460 (GRCm38)	missense	possibly damaging	0.91
R2880:Nbea	UTSW	3	55,647,358 (GRCm38)	missense	probably benign	0.04
R2881:Nbea	UTSW	3	55,647,358 (GRCm38)	missense	probably benign	0.04
R2940:Nbea	UTSW	3	55,934,624 (GRCm38)	missense	probably benign	0.24
R3500:Nbea	UTSW	3	55,681,010 (GRCm38)	missense	possibly damaging	0.88
R3765:Nbea	UTSW	3	56,005,549 (GRCm38)	missense	probably damaging	1.00
R3790:Nbea	UTSW	3	56,005,029 (GRCm38)	missense	probably benign
R3808:Nbea	UTSW	3	55,717,848 (GRCm38)	missense	probably benign	0.02
R3845:Nbea	UTSW	3	56,086,292 (GRCm38)	splice site	probably benign
R4182:Nbea	UTSW	3	56,008,427 (GRCm38)	missense	probably damaging	0.99
R4385:Nbea	UTSW	3	56,000,638 (GRCm38)	missense	possibly damaging	0.77
R4419:Nbea	UTSW	3	56,009,600 (GRCm38)	missense	probably damaging	1.00
R4426:Nbea	UTSW	3	56,082,379 (GRCm38)	missense	probably damaging	0.98
R4451:Nbea	UTSW	3	55,992,332 (GRCm38)	critical splice donor site	probably null
R4456:Nbea	UTSW	3	55,643,784 (GRCm38)	missense	probably benign	0.00
R4604:Nbea	UTSW	3	55,723,648 (GRCm38)	missense	probably benign	0.18
R4687:Nbea	UTSW	3	56,058,065 (GRCm38)	missense	probably damaging	1.00
R4758:Nbea	UTSW	3	56,005,403 (GRCm38)	missense	probably benign
R4840:Nbea	UTSW	3	55,710,670 (GRCm38)	missense	probably benign	0.37
R4888:Nbea	UTSW	3	56,005,355 (GRCm38)	missense	possibly damaging	0.61
R4954:Nbea	UTSW	3	56,035,958 (GRCm38)	missense	probably damaging	1.00
R4972:Nbea	UTSW	3	56,085,246 (GRCm38)	missense	probably damaging	0.99
R4980:Nbea	UTSW	3	55,953,045 (GRCm38)	missense	probably benign	0.00
R4980:Nbea	UTSW	3	55,647,351 (GRCm38)	splice site	probably null
R5104:Nbea	UTSW	3	56,079,927 (GRCm38)	missense	probably damaging	1.00
R5139:Nbea	UTSW	3	55,626,963 (GRCm38)	missense	possibly damaging	0.90
R5166:Nbea	UTSW	3	56,019,453 (GRCm38)	missense	probably damaging	1.00
R5347:Nbea	UTSW	3	56,040,876 (GRCm38)	missense	probably damaging	1.00
R5350:Nbea	UTSW	3	56,019,424 (GRCm38)	missense	probably damaging	1.00
R5418:Nbea	UTSW	3	55,645,989 (GRCm38)	missense	possibly damaging	0.86
R5586:Nbea	UTSW	3	55,631,971 (GRCm38)	missense	probably benign	0.08
R5627:Nbea	UTSW	3	55,992,345 (GRCm38)	missense	probably damaging	1.00
R5683:Nbea	UTSW	3	55,628,586 (GRCm38)	missense	possibly damaging	0.53
R5765:Nbea	UTSW	3	56,005,298 (GRCm38)	missense	probably benign	0.15
R5853:Nbea	UTSW	3	55,992,401 (GRCm38)	missense	probably damaging	1.00
R5858:Nbea	UTSW	3	55,953,034 (GRCm38)	critical splice donor site	probably null
R5955:Nbea	UTSW	3	55,680,983 (GRCm38)	missense	probably benign	0.00
R5976:Nbea	UTSW	3	55,853,847 (GRCm38)	missense	probably benign	0.30
R6039:Nbea	UTSW	3	56,005,117 (GRCm38)	missense	probably benign	0.00
R6039:Nbea	UTSW	3	56,005,117 (GRCm38)	missense	probably benign	0.00
R6043:Nbea	UTSW	3	55,786,475 (GRCm38)	missense	probably benign	0.32
R6122:Nbea	UTSW	3	56,029,896 (GRCm38)	missense	probably damaging	1.00
R6218:Nbea	UTSW	3	55,628,484 (GRCm38)	missense	probably damaging	0.97
R6331:Nbea	UTSW	3	56,000,616 (GRCm38)	missense	possibly damaging	0.94
R6334:Nbea	UTSW	3	56,037,149 (GRCm38)	missense	probably damaging	1.00
R6393:Nbea	UTSW	3	56,091,119 (GRCm38)	missense	probably damaging	1.00
R6411:Nbea	UTSW	3	55,805,357 (GRCm38)	missense	probably benign	0.01
R6457:Nbea	UTSW	3	56,000,569 (GRCm38)	missense	probably damaging	1.00
R6476:Nbea	UTSW	3	56,004,806 (GRCm38)	missense	probably benign	0.00
R6488:Nbea	UTSW	3	55,717,843 (GRCm38)	missense	probably damaging	0.99
R6700:Nbea	UTSW	3	56,082,448 (GRCm38)	missense	possibly damaging	0.89
R6702:Nbea	UTSW	3	56,005,502 (GRCm38)	missense	probably benign	0.06
R6752:Nbea	UTSW	3	56,037,219 (GRCm38)	missense	probably benign
R6752:Nbea	UTSW	3	55,968,309 (GRCm38)	missense	probably benign	0.02
R6804:Nbea	UTSW	3	56,087,453 (GRCm38)	missense	probably benign	0.37
R6901:Nbea	UTSW	3	56,019,415 (GRCm38)	missense	probably damaging	1.00
R6933:Nbea	UTSW	3	55,723,610 (GRCm38)	missense	possibly damaging	0.63
R7124:Nbea	UTSW	3	55,992,444 (GRCm38)	missense	probably damaging	1.00
R7308:Nbea	UTSW	3	56,091,031 (GRCm38)	missense	probably damaging	1.00
R7405:Nbea	UTSW	3	55,805,266 (GRCm38)	missense	possibly damaging	0.94
R7669:Nbea	UTSW	3	55,717,779 (GRCm38)	missense	probably damaging	1.00
R7762:Nbea	UTSW	3	55,649,705 (GRCm38)	missense	probably damaging	1.00
R7833:Nbea	UTSW	3	56,002,797 (GRCm38)	missense	probably damaging	1.00
R7885:Nbea	UTSW	3	55,665,689 (GRCm38)	missense	probably damaging	0.97
R7935:Nbea	UTSW	3	56,058,665 (GRCm38)	missense	probably damaging	1.00
R8050:Nbea	UTSW	3	55,987,981 (GRCm38)	missense	probably damaging	0.99
R8108:Nbea	UTSW	3	55,819,315 (GRCm38)	missense	probably benign	0.11
R8290:Nbea	UTSW	3	56,058,635 (GRCm38)	nonsense	probably null
R8314:Nbea	UTSW	3	56,009,251 (GRCm38)	missense	probably damaging	0.99
R8321:Nbea	UTSW	3	56,183,097 (GRCm38)	missense	possibly damaging	0.86
R8376:Nbea	UTSW	3	55,643,655 (GRCm38)	missense	possibly damaging	0.79
R8410:Nbea	UTSW	3	56,037,263 (GRCm38)	missense	probably damaging	1.00
R8556:Nbea	UTSW	3	55,647,386 (GRCm38)	missense	probably benign	0.25
R8753:Nbea	UTSW	3	55,626,908 (GRCm38)	missense	probably damaging	1.00
R8844:Nbea	UTSW	3	56,090,994 (GRCm38)	missense	probably damaging	0.97
R8884:Nbea	UTSW	3	55,805,299 (GRCm38)	missense	probably benign	0.00
R8886:Nbea	UTSW	3	56,058,727 (GRCm38)	missense	probably damaging	1.00
R8890:Nbea	UTSW	3	56,019,363 (GRCm38)	splice site	probably benign
R9004:Nbea	UTSW	3	56,002,938 (GRCm38)	missense	probably benign	0.01
R9022:Nbea	UTSW	3	55,643,689 (GRCm38)	missense	possibly damaging	0.79
R9080:Nbea	UTSW	3	56,005,095 (GRCm38)	nonsense	probably null
R9087:Nbea	UTSW	3	55,642,736 (GRCm38)	critical splice donor site	probably null
R9104:Nbea	UTSW	3	55,955,388 (GRCm38)	missense	probably benign
R9165:Nbea	UTSW	3	56,004,868 (GRCm38)	missense	probably benign	0.15
R9219:Nbea	UTSW	3	56,090,972 (GRCm38)	frame shift	probably null
R9221:Nbea	UTSW	3	56,090,972 (GRCm38)	frame shift	probably null
R9222:Nbea	UTSW	3	56,090,972 (GRCm38)	frame shift	probably null
R9260:Nbea	UTSW	3	55,983,812 (GRCm38)	missense	possibly damaging	0.50
R9263:Nbea	UTSW	3	56,090,972 (GRCm38)	frame shift	probably null
R9265:Nbea	UTSW	3	56,090,972 (GRCm38)	frame shift	probably null
R9294:Nbea	UTSW	3	56,091,092 (GRCm38)	missense	probably benign	0.00
R9360:Nbea	UTSW	3	56,035,898 (GRCm38)	missense	possibly damaging	0.96
R9387:Nbea	UTSW	3	55,991,039 (GRCm38)	missense	probably benign	0.12
R9428:Nbea	UTSW	3	56,090,972 (GRCm38)	frame shift	probably null
R9435:Nbea	UTSW	3	56,035,888 (GRCm38)	missense	possibly damaging	0.63
R9507:Nbea	UTSW	3	55,665,590 (GRCm38)	missense	probably damaging	1.00
R9514:Nbea	UTSW	3	56,029,945 (GRCm38)	missense	probably damaging	1.00
R9516:Nbea	UTSW	3	56,029,945 (GRCm38)	missense	probably damaging	1.00
R9674:Nbea	UTSW	3	56,058,762 (GRCm38)	missense	probably damaging	1.00
R9688:Nbea	UTSW	3	55,649,744 (GRCm38)	missense	probably benign	0.42
R9709:Nbea	UTSW	3	55,786,458 (GRCm38)	nonsense	probably null
RF051:Nbea	UTSW	3	56,009,212 (GRCm38)	critical splice donor site	probably benign
X0018:Nbea	UTSW	3	56,036,048 (GRCm38)	missense	probably benign	0.39
Z1088:Nbea	UTSW	3	55,723,163 (GRCm38)	missense	probably benign	0.34
Z1177:Nbea	UTSW	3	56,031,550 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TCCAAAGTTGTGGCAGTCATTTC -3'
(R):5'- CAATGTGCATGGAAGTGTGG -3'

Sequencing Primer
(F):5'- AGTTGACGATGCTAACTCTCG -3'
(R):5'- CAATGTGCATGGAAGTGTGGGTATC -3'

Posted On

2019-06-26