Incidental Mutation 'R7214:Dscaml1'
| ID |
561316 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dscaml1
|
| Ensembl Gene |
ENSMUSG00000032087 |
| Gene Name |
DS cell adhesion molecule like 1 |
| Synonyms |
4921507G06Rik, 4930435C18Rik |
| MMRRC Submission |
045286-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.416)
|
| Stock # |
R7214 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
45338735-45665011 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 45581437 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 419
(I419F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000034592
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000034592]
[ENSMUST00000213919]
|
| AlphaFold |
Q4VA61 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000034592
AA Change: I419F
PolyPhen 2
Score 0.014 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000034592
Gene: ENSMUSG00000032087
AA Change: I419F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
17 |
N/A |
INTRINSIC |
|
low complexity region
|
28 |
55 |
N/A |
INTRINSIC |
|
IG_like
|
96 |
168 |
1.22e0 |
SMART |
|
IG
|
189 |
277 |
1.15e-3 |
SMART |
|
IGc2
|
296 |
359 |
2.54e-14 |
SMART |
|
IGc2
|
385 |
451 |
8.12e-13 |
SMART |
|
IGc2
|
478 |
550 |
9.55e-10 |
SMART |
|
IGc2
|
575 |
640 |
9.78e-7 |
SMART |
|
IGc2
|
666 |
734 |
5.93e-6 |
SMART |
|
IGc2
|
760 |
832 |
6.75e-10 |
SMART |
|
IG
|
853 |
943 |
1e-3 |
SMART |
|
FN3
|
945 |
1029 |
6.64e-7 |
SMART |
|
FN3
|
1045 |
1133 |
9.46e-12 |
SMART |
|
FN3
|
1148 |
1234 |
3.2e-9 |
SMART |
|
FN3
|
1249 |
1332 |
3.48e-10 |
SMART |
|
IGc2
|
1363 |
1428 |
1.49e-11 |
SMART |
|
FN3
|
1442 |
1522 |
3.42e-9 |
SMART |
|
FN3
|
1537 |
1618 |
2.14e-1 |
SMART |
|
low complexity region
|
1671 |
1683 |
N/A |
INTRINSIC |
|
low complexity region
|
2018 |
2026 |
N/A |
INTRINSIC |
|
low complexity region
|
2035 |
2069 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000213919
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000216078
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the Ig superfamily of cell adhesion molecules and is involved in neuronal differentiation. The encoded membrane-bound protein localizes to the cell surface, where it forms aggregates that repel neuronal processes of the same cell type. [provided by RefSeq, Sep 2016]
PHENOTYPE: Mice homozygous for a gene trapped allele exhibit impaired self-avoidance in multiple cell types in the retina. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(4) : Gene trapped(4) |
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adgrg5 |
C |
T |
8: 95,660,646 (GRCm39) |
T95I |
|
Het |
| Arap2 |
C |
T |
5: 62,906,681 (GRCm39) |
V113I |
probably benign |
Het |
| Atraid |
C |
T |
5: 31,209,590 (GRCm39) |
Q85* |
probably null |
Het |
| Bcdin3d |
T |
C |
15: 99,368,344 (GRCm39) |
D285G |
probably benign |
Het |
| Bmal1 |
T |
A |
7: 112,898,610 (GRCm39) |
I346K |
probably benign |
Het |
| Carmil3 |
T |
C |
14: 55,736,069 (GRCm39) |
W604R |
probably damaging |
Het |
| Ccl6 |
C |
T |
11: 83,480,582 (GRCm39) |
|
probably null |
Het |
| Cct4 |
C |
T |
11: 22,940,616 (GRCm39) |
|
probably benign |
Het |
| Cd2ap |
C |
T |
17: 43,156,285 (GRCm39) |
R84Q |
possibly damaging |
Het |
| Cdt1 |
T |
A |
8: 123,295,012 (GRCm39) |
|
probably null |
Het |
| Cln3 |
C |
T |
7: 126,181,942 (GRCm39) |
G40D |
probably damaging |
Het |
| Crlf3 |
T |
C |
11: 79,955,216 (GRCm39) |
S47G |
possibly damaging |
Het |
| Csrp3 |
T |
C |
7: 48,480,385 (GRCm39) |
K193R |
probably benign |
Het |
| Cxcl3 |
A |
C |
5: 90,934,219 (GRCm39) |
E33A |
probably damaging |
Het |
| Cyp11b1 |
T |
C |
15: 74,708,708 (GRCm39) |
D362G |
probably benign |
Het |
| Dnah2 |
T |
C |
11: 69,321,935 (GRCm39) |
D3795G |
probably damaging |
Het |
| Dnah3 |
G |
A |
7: 119,521,965 (GRCm39) |
A4076V |
probably damaging |
Het |
| Dnaja3 |
T |
A |
16: 4,519,046 (GRCm39) |
I380N |
possibly damaging |
Het |
| Dock10 |
T |
A |
1: 80,546,246 (GRCm39) |
H785L |
probably benign |
Het |
| Dop1b |
T |
G |
16: 93,607,023 (GRCm39) |
F2226V |
possibly damaging |
Het |
| Dyrk4 |
T |
A |
6: 126,862,200 (GRCm39) |
I431F |
probably benign |
Het |
| Endog |
C |
T |
2: 30,062,902 (GRCm39) |
R181C |
probably damaging |
Het |
| Fam90a1a |
A |
T |
8: 22,453,641 (GRCm39) |
Y332F |
probably benign |
Het |
| Fastkd3 |
T |
C |
13: 68,737,499 (GRCm39) |
I588T |
probably benign |
Het |
| Galnt9 |
G |
A |
5: 110,737,694 (GRCm39) |
V217I |
probably benign |
Het |
| Gm973 |
A |
T |
1: 59,601,888 (GRCm39) |
R501* |
probably null |
Het |
| Gnptab |
C |
T |
10: 88,215,019 (GRCm39) |
|
probably benign |
Het |
| Gpn1 |
T |
C |
5: 31,660,761 (GRCm39) |
F184S |
probably damaging |
Het |
| Imp3 |
G |
T |
9: 56,845,007 (GRCm39) |
V73L |
probably benign |
Het |
| Ipo11 |
T |
C |
13: 107,032,365 (GRCm39) |
D259G |
probably null |
Het |
| Jag1 |
T |
C |
2: 136,948,802 (GRCm39) |
S142G |
probably benign |
Het |
| Klhl5 |
A |
T |
5: 65,289,098 (GRCm39) |
E120V |
probably benign |
Het |
| Lct |
C |
A |
1: 128,228,197 (GRCm39) |
V1099L |
probably benign |
Het |
| Lrba |
G |
C |
3: 86,235,633 (GRCm39) |
W912C |
probably damaging |
Het |
| Lss |
C |
T |
10: 76,383,305 (GRCm39) |
T535I |
probably damaging |
Het |
| Mcts2 |
T |
C |
2: 152,529,297 (GRCm39) |
I36T |
probably benign |
Het |
| Meikin |
T |
A |
11: 54,302,738 (GRCm39) |
N383K |
probably benign |
Het |
| Myo1g |
T |
C |
11: 6,461,055 (GRCm39) |
Y663C |
probably damaging |
Het |
| Nadk2 |
T |
A |
15: 9,108,342 (GRCm39) |
M419K |
probably damaging |
Het |
| Nbeal1 |
G |
C |
1: 60,276,310 (GRCm39) |
V684L |
probably benign |
Het |
| Nfat5 |
T |
C |
8: 108,020,515 (GRCm39) |
S20P |
probably damaging |
Het |
| Nlrp1a |
C |
T |
11: 71,014,119 (GRCm39) |
C377Y |
probably damaging |
Het |
| Nlrp9a |
T |
C |
7: 26,250,463 (GRCm39) |
V76A |
probably damaging |
Het |
| Nrap |
C |
A |
19: 56,366,567 (GRCm39) |
A341S |
probably benign |
Het |
| Ntng2 |
T |
C |
2: 29,117,732 (GRCm39) |
S239G |
probably damaging |
Het |
| Nup188 |
T |
A |
2: 30,197,566 (GRCm39) |
C207S |
possibly damaging |
Het |
| Or10a4 |
T |
C |
7: 106,697,619 (GRCm39) |
*316R |
probably null |
Het |
| Or10ak7 |
T |
A |
4: 118,791,146 (GRCm39) |
I300F |
possibly damaging |
Het |
| Or1j17 |
T |
C |
2: 36,578,107 (GRCm39) |
I31T |
probably benign |
Het |
| Or2ag1 |
T |
C |
7: 106,473,474 (GRCm39) |
|
probably benign |
Het |
| Or5b118 |
T |
A |
19: 13,448,337 (GRCm39) |
M1K |
probably null |
Het |
| Or8c13 |
A |
C |
9: 38,091,318 (GRCm39) |
V267G |
probably damaging |
Het |
| Or8k31-ps1 |
C |
T |
2: 86,356,150 (GRCm39) |
V124I |
probably damaging |
Het |
| Pcdhgb2 |
C |
A |
18: 37,823,159 (GRCm39) |
A50E |
probably damaging |
Het |
| Pgap1 |
A |
T |
1: 54,582,220 (GRCm39) |
M209K |
possibly damaging |
Het |
| Plbd1 |
T |
A |
6: 136,589,829 (GRCm39) |
D463V |
probably damaging |
Het |
| Plcg2 |
T |
A |
8: 118,310,288 (GRCm39) |
I380N |
probably damaging |
Het |
| Pnpt1 |
T |
C |
11: 29,087,285 (GRCm39) |
W184R |
probably damaging |
Het |
| Pptc7 |
G |
A |
5: 122,451,840 (GRCm39) |
V202I |
probably benign |
Het |
| Prpf6 |
C |
T |
2: 181,282,389 (GRCm39) |
A510V |
probably damaging |
Het |
| Prr5l |
T |
C |
2: 101,559,777 (GRCm39) |
Y235C |
probably benign |
Het |
| Ptprk |
T |
C |
10: 28,450,905 (GRCm39) |
V1022A |
probably benign |
Het |
| Rbl2 |
T |
C |
8: 91,810,057 (GRCm39) |
|
probably null |
Het |
| Rmnd1 |
T |
C |
10: 4,360,753 (GRCm39) |
K348E |
probably benign |
Het |
| Rsf1 |
CGGCGGC |
CGGCGGCGGGGGCGGC |
7: 97,229,136 (GRCm39) |
|
probably benign |
Het |
| Sacs |
T |
A |
14: 61,429,241 (GRCm39) |
N433K |
probably benign |
Het |
| Scyl1 |
T |
C |
19: 5,810,057 (GRCm39) |
T590A |
probably benign |
Het |
| Sdhd |
A |
G |
9: 50,508,533 (GRCm39) |
V111A |
possibly damaging |
Het |
| Sec24b |
G |
T |
3: 129,827,509 (GRCm39) |
P330Q |
probably benign |
Het |
| Serpinb6d |
C |
T |
13: 33,848,128 (GRCm39) |
P31S |
probably damaging |
Het |
| Slc26a9 |
A |
T |
1: 131,687,211 (GRCm39) |
R457W |
probably damaging |
Het |
| Slc5a8 |
G |
A |
10: 88,755,364 (GRCm39) |
M490I |
probably benign |
Het |
| Slx4 |
A |
G |
16: 3,806,844 (GRCm39) |
I533T |
probably benign |
Het |
| Slx4ip |
T |
A |
2: 136,888,650 (GRCm39) |
F110L |
probably benign |
Het |
| Smchd1 |
T |
C |
17: 71,652,359 (GRCm39) |
R2000G |
probably benign |
Het |
| Snx8 |
T |
C |
5: 140,346,008 (GRCm39) |
E75G |
possibly damaging |
Het |
| Stab2 |
C |
A |
10: 86,735,705 (GRCm39) |
C1292F |
probably damaging |
Het |
| Swt1 |
A |
T |
1: 151,270,364 (GRCm39) |
M617K |
possibly damaging |
Het |
| Thoc2l |
A |
G |
5: 104,670,229 (GRCm39) |
T1584A |
probably benign |
Het |
| Tiam2 |
T |
A |
17: 3,568,687 (GRCm39) |
I1611N |
possibly damaging |
Het |
| Tmem63b |
T |
G |
17: 45,972,748 (GRCm39) |
N682T |
probably benign |
Het |
| Trio |
C |
T |
15: 27,871,273 (GRCm39) |
V674M |
probably damaging |
Het |
| Trpc3 |
G |
A |
3: 36,704,286 (GRCm39) |
T557M |
possibly damaging |
Het |
| Vac14 |
T |
G |
8: 111,397,674 (GRCm39) |
L463R |
probably damaging |
Het |
| Vmn2r43 |
C |
T |
7: 8,256,379 (GRCm39) |
|
probably null |
Het |
| Wdr49 |
A |
T |
3: 75,265,751 (GRCm39) |
Y232N |
possibly damaging |
Het |
| Wdr90 |
T |
C |
17: 26,064,367 (GRCm39) |
M1835V |
probably benign |
Het |
| Xpc |
T |
C |
6: 91,469,320 (GRCm39) |
E809G |
probably damaging |
Het |
| Zfhx3 |
A |
T |
8: 109,675,493 (GRCm39) |
Q2181L |
probably damaging |
Het |
| Zfp442 |
T |
C |
2: 150,251,201 (GRCm39) |
T234A |
probably benign |
Het |
| Zfp764 |
A |
T |
7: 127,004,450 (GRCm39) |
M227K |
probably benign |
Het |
| Zfp764l1 |
A |
G |
7: 126,990,695 (GRCm39) |
S431P |
probably benign |
Het |
| Zfp957 |
A |
G |
14: 79,450,750 (GRCm39) |
S350P |
unknown |
Het |
| Zscan29 |
T |
A |
2: 120,999,761 (GRCm39) |
K147* |
probably null |
Het |
|
| Other mutations in Dscaml1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00418:Dscaml1
|
APN |
9 |
45,581,498 (GRCm39) |
nonsense |
probably null |
|
|
IGL00497:Dscaml1
|
APN |
9 |
45,663,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00895:Dscaml1
|
APN |
9 |
45,662,551 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01011:Dscaml1
|
APN |
9 |
45,594,970 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL01086:Dscaml1
|
APN |
9 |
45,613,960 (GRCm39) |
splice site |
probably benign |
|
|
IGL01125:Dscaml1
|
APN |
9 |
45,660,930 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01132:Dscaml1
|
APN |
9 |
45,663,626 (GRCm39) |
nonsense |
probably null |
|
|
IGL01356:Dscaml1
|
APN |
9 |
45,658,155 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01459:Dscaml1
|
APN |
9 |
45,653,981 (GRCm39) |
nonsense |
probably null |
|
|
IGL01552:Dscaml1
|
APN |
9 |
45,359,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02033:Dscaml1
|
APN |
9 |
45,595,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02044:Dscaml1
|
APN |
9 |
45,658,241 (GRCm39) |
nonsense |
probably null |
|
|
IGL02095:Dscaml1
|
APN |
9 |
45,359,001 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02166:Dscaml1
|
APN |
9 |
45,594,999 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02262:Dscaml1
|
APN |
9 |
45,643,378 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL02262:Dscaml1
|
APN |
9 |
45,656,414 (GRCm39) |
missense |
probably benign |
|
|
IGL02340:Dscaml1
|
APN |
9 |
45,581,474 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02604:Dscaml1
|
APN |
9 |
45,655,626 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02619:Dscaml1
|
APN |
9 |
45,359,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02805:Dscaml1
|
APN |
9 |
45,359,195 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03409:Dscaml1
|
APN |
9 |
45,581,401 (GRCm39) |
missense |
probably damaging |
1.00 |
|
D3080:Dscaml1
|
UTSW |
9 |
45,595,623 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL03050:Dscaml1
|
UTSW |
9 |
45,654,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0149:Dscaml1
|
UTSW |
9 |
45,653,978 (GRCm39) |
nonsense |
probably null |
|
|
R0582:Dscaml1
|
UTSW |
9 |
45,579,562 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0629:Dscaml1
|
UTSW |
9 |
45,632,716 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0632:Dscaml1
|
UTSW |
9 |
45,643,432 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0815:Dscaml1
|
UTSW |
9 |
45,656,372 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1162:Dscaml1
|
UTSW |
9 |
45,663,647 (GRCm39) |
splice site |
probably benign |
|
|
R1449:Dscaml1
|
UTSW |
9 |
45,653,521 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1474:Dscaml1
|
UTSW |
9 |
45,596,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1481:Dscaml1
|
UTSW |
9 |
45,583,941 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1533:Dscaml1
|
UTSW |
9 |
45,361,882 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1542:Dscaml1
|
UTSW |
9 |
45,660,738 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R1572:Dscaml1
|
UTSW |
9 |
45,632,631 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1627:Dscaml1
|
UTSW |
9 |
45,664,445 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1634:Dscaml1
|
UTSW |
9 |
45,584,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1713:Dscaml1
|
UTSW |
9 |
45,663,988 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1777:Dscaml1
|
UTSW |
9 |
45,595,054 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1812:Dscaml1
|
UTSW |
9 |
45,662,584 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1834:Dscaml1
|
UTSW |
9 |
45,594,930 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1907:Dscaml1
|
UTSW |
9 |
45,651,778 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1953:Dscaml1
|
UTSW |
9 |
45,581,522 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2056:Dscaml1
|
UTSW |
9 |
45,661,430 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2193:Dscaml1
|
UTSW |
9 |
45,596,532 (GRCm39) |
missense |
probably benign |
0.21 |
|
R2497:Dscaml1
|
UTSW |
9 |
45,656,376 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3768:Dscaml1
|
UTSW |
9 |
45,643,435 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3891:Dscaml1
|
UTSW |
9 |
45,628,782 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4110:Dscaml1
|
UTSW |
9 |
45,643,366 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4706:Dscaml1
|
UTSW |
9 |
45,361,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4716:Dscaml1
|
UTSW |
9 |
45,361,890 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4719:Dscaml1
|
UTSW |
9 |
45,583,993 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4770:Dscaml1
|
UTSW |
9 |
45,581,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Dscaml1
|
UTSW |
9 |
45,656,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5167:Dscaml1
|
UTSW |
9 |
45,628,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5346:Dscaml1
|
UTSW |
9 |
45,361,857 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5737:Dscaml1
|
UTSW |
9 |
45,656,483 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5977:Dscaml1
|
UTSW |
9 |
45,632,596 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6073:Dscaml1
|
UTSW |
9 |
45,361,881 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6276:Dscaml1
|
UTSW |
9 |
45,579,458 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R6415:Dscaml1
|
UTSW |
9 |
45,594,975 (GRCm39) |
nonsense |
probably null |
|
|
R6527:Dscaml1
|
UTSW |
9 |
45,623,482 (GRCm39) |
nonsense |
probably null |
|
|
R6582:Dscaml1
|
UTSW |
9 |
45,664,104 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6655:Dscaml1
|
UTSW |
9 |
45,658,235 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6772:Dscaml1
|
UTSW |
9 |
45,621,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6799:Dscaml1
|
UTSW |
9 |
45,361,881 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6892:Dscaml1
|
UTSW |
9 |
45,595,128 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6918:Dscaml1
|
UTSW |
9 |
45,341,805 (GRCm39) |
missense |
probably benign |
|
|
R6967:Dscaml1
|
UTSW |
9 |
45,585,821 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7286:Dscaml1
|
UTSW |
9 |
45,654,044 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7315:Dscaml1
|
UTSW |
9 |
45,656,423 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7338:Dscaml1
|
UTSW |
9 |
45,585,802 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7343:Dscaml1
|
UTSW |
9 |
45,664,214 (GRCm39) |
missense |
probably benign |
|
|
R7395:Dscaml1
|
UTSW |
9 |
45,613,703 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R7439:Dscaml1
|
UTSW |
9 |
45,621,624 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7484:Dscaml1
|
UTSW |
9 |
45,660,744 (GRCm39) |
splice site |
probably null |
|
|
R7545:Dscaml1
|
UTSW |
9 |
45,596,681 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7979:Dscaml1
|
UTSW |
9 |
45,595,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8005:Dscaml1
|
UTSW |
9 |
45,628,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8181:Dscaml1
|
UTSW |
9 |
45,658,140 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8262:Dscaml1
|
UTSW |
9 |
45,658,438 (GRCm39) |
intron |
probably benign |
|
|
R8428:Dscaml1
|
UTSW |
9 |
45,653,884 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8725:Dscaml1
|
UTSW |
9 |
45,341,759 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8727:Dscaml1
|
UTSW |
9 |
45,341,759 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8796:Dscaml1
|
UTSW |
9 |
45,359,026 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8840:Dscaml1
|
UTSW |
9 |
45,634,718 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9291:Dscaml1
|
UTSW |
9 |
45,359,251 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9394:Dscaml1
|
UTSW |
9 |
45,661,354 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R9610:Dscaml1
|
UTSW |
9 |
45,579,522 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9611:Dscaml1
|
UTSW |
9 |
45,579,522 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9653:Dscaml1
|
UTSW |
9 |
45,643,466 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9699:Dscaml1
|
UTSW |
9 |
45,654,315 (GRCm39) |
missense |
probably damaging |
0.97 |
|
X0058:Dscaml1
|
UTSW |
9 |
45,663,426 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Dscaml1
|
UTSW |
9 |
45,584,089 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTAGCCACATGCCATCACGG -3'
(R):5'- GACTGCAGATCCACTCTTCC -3'
Sequencing Primer
(F):5'- ATGCCATCACGGTTAAGGTC -3'
(R):5'- AGATCCACTCTTCCCTGCCAC -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation