Incidental Mutation 'R7216:Tnrc6a'
| ID |
561467 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnrc6a
|
| Ensembl Gene |
ENSMUSG00000052707 |
| Gene Name |
trinucleotide repeat containing 6a |
| Synonyms |
3110054G10Rik, 2010321I05Rik, Tnrc6, CAGH26, D130023A07Rik |
| MMRRC Submission |
045288-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.850)
|
| Stock # |
R7216 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
122723108-122794519 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 122770718 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Threonine
at position 836
(I836T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091595
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094053]
[ENSMUST00000205514]
[ENSMUST00000206014]
[ENSMUST00000206888]
|
| AlphaFold |
Q3UHK8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094053
AA Change: I836T
PolyPhen 2
Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)
|
| SMART Domains |
Protein: ENSMUSP00000091595
Gene: ENSMUSG00000052707
AA Change: I836T
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
5 |
54 |
N/A |
INTRINSIC |
|
low complexity region
|
69 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
93 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
281 |
294 |
N/A |
INTRINSIC |
|
low complexity region
|
430 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
568 |
590 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
690 |
853 |
3.51e-6 |
PROSPERO |
|
low complexity region
|
858 |
871 |
N/A |
INTRINSIC |
|
Pfam:Ago_hook
|
1028 |
1190 |
1.2e-29 |
PFAM |
|
low complexity region
|
1284 |
1296 |
N/A |
INTRINSIC |
|
low complexity region
|
1301 |
1316 |
N/A |
INTRINSIC |
|
low complexity region
|
1337 |
1376 |
N/A |
INTRINSIC |
|
low complexity region
|
1386 |
1392 |
N/A |
INTRINSIC |
|
Pfam:TNRC6-PABC_bdg
|
1439 |
1714 |
1.5e-126 |
PFAM |
|
RRM
|
1717 |
1784 |
4.95e-2 |
SMART |
|
low complexity region
|
1808 |
1820 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000205514
|
| Predicted Effect |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000206014
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000206888
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein is highly similar to a human protein that functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The human protein associates with messenger RNAs and argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies, and inhibiting its expression delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit partial embryonic lethality during organogenesis associated with impaired hematopoiesis. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(21) : Gene trapped(21) |
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Akap6 |
T |
A |
12: 53,187,240 (GRCm39) |
N1551K |
probably benign |
Het |
| Amy2a1 |
T |
C |
3: 113,324,090 (GRCm39) |
D150G |
possibly damaging |
Het |
| Atp2b1 |
T |
A |
10: 98,822,839 (GRCm39) |
C165S |
probably benign |
Het |
| Atp2c1 |
A |
T |
9: 105,344,930 (GRCm39) |
D102E |
probably benign |
Het |
| Capn8 |
C |
A |
1: 182,426,363 (GRCm39) |
R233S |
possibly damaging |
Het |
| Cd48 |
T |
C |
1: 171,523,390 (GRCm39) |
S78P |
probably damaging |
Het |
| Clasp1 |
T |
A |
1: 118,475,648 (GRCm39) |
D944E |
probably benign |
Het |
| Clip2 |
A |
G |
5: 134,531,771 (GRCm39) |
M678T |
probably benign |
Het |
| Clmp |
T |
C |
9: 40,672,205 (GRCm39) |
Y12H |
possibly damaging |
Het |
| Col22a1 |
A |
T |
15: 71,845,694 (GRCm39) |
V356D |
probably damaging |
Het |
| Copg2 |
A |
T |
6: 30,862,535 (GRCm39) |
D101E |
probably damaging |
Het |
| Cpsf6 |
G |
A |
10: 117,197,928 (GRCm39) |
P229S |
unknown |
Het |
| Dgke |
T |
C |
11: 88,941,163 (GRCm39) |
D340G |
probably benign |
Het |
| Dlg1 |
TAAA |
TAA |
16: 31,615,736 (GRCm39) |
|
probably null |
Het |
| Dlg5 |
G |
A |
14: 24,186,706 (GRCm39) |
Q1865* |
probably null |
Het |
| Dnajc2 |
C |
T |
5: 21,981,777 (GRCm39) |
R123Q |
probably damaging |
Het |
| Efcab3 |
A |
T |
11: 104,771,375 (GRCm39) |
K2633N |
possibly damaging |
Het |
| Egln2 |
T |
C |
7: 26,859,254 (GRCm39) |
D365G |
probably damaging |
Het |
| Epha4 |
T |
C |
1: 77,421,621 (GRCm39) |
D287G |
probably damaging |
Het |
| Fat4 |
A |
G |
3: 38,945,192 (GRCm39) |
T1362A |
probably damaging |
Het |
| Flt4 |
A |
G |
11: 49,525,508 (GRCm39) |
T685A |
possibly damaging |
Het |
| Fras1 |
T |
C |
5: 96,887,173 (GRCm39) |
Y2652H |
probably damaging |
Het |
| Gas2 |
A |
G |
7: 51,547,005 (GRCm39) |
E52G |
possibly damaging |
Het |
| Gm5093 |
A |
T |
17: 46,751,014 (GRCm39) |
D4E |
not run |
Het |
| Gm6370 |
A |
T |
5: 146,430,723 (GRCm39) |
T303S |
probably benign |
Het |
| Gpr161 |
A |
G |
1: 165,134,115 (GRCm39) |
I126V |
probably benign |
Het |
| Gpr63 |
T |
C |
4: 25,008,038 (GRCm39) |
L254P |
probably damaging |
Het |
| H2-M9 |
C |
T |
17: 36,951,594 (GRCm39) |
V294I |
probably benign |
Het |
| Insr |
T |
A |
8: 3,253,034 (GRCm39) |
N375I |
possibly damaging |
Het |
| Ints1 |
T |
C |
5: 139,754,739 (GRCm39) |
N600S |
possibly damaging |
Het |
| Ints10 |
A |
G |
8: 69,274,809 (GRCm39) |
N628S |
probably damaging |
Het |
| Irf2 |
A |
G |
8: 47,246,591 (GRCm39) |
T20A |
probably benign |
Het |
| Irs1 |
T |
A |
1: 82,267,476 (GRCm39) |
T247S |
probably damaging |
Het |
| Islr |
C |
T |
9: 58,064,250 (GRCm39) |
S419N |
unknown |
Het |
| Kcna2 |
T |
A |
3: 107,012,109 (GRCm39) |
I230N |
probably damaging |
Het |
| Kif3c |
C |
A |
12: 3,416,126 (GRCm39) |
A49E |
probably benign |
Het |
| Kifap3 |
A |
T |
1: 163,623,558 (GRCm39) |
K108N |
probably damaging |
Het |
| Lama3 |
T |
A |
18: 12,563,057 (GRCm39) |
F527I |
probably damaging |
Het |
| Layn |
A |
G |
9: 50,988,352 (GRCm39) |
|
probably benign |
Het |
| Lims2 |
G |
T |
18: 32,090,315 (GRCm39) |
W276L |
probably damaging |
Het |
| Lsp1 |
T |
C |
7: 142,042,179 (GRCm39) |
L133S |
probably damaging |
Het |
| Map3k6 |
T |
G |
4: 132,974,211 (GRCm39) |
V536G |
probably damaging |
Het |
| Med7 |
T |
A |
11: 46,331,681 (GRCm39) |
L92H |
probably damaging |
Het |
| Mllt1 |
A |
G |
17: 57,234,042 (GRCm39) |
V48A |
probably damaging |
Het |
| Mtcl2 |
T |
C |
2: 156,860,290 (GRCm39) |
R1650G |
possibly damaging |
Het |
| Neurl4 |
T |
A |
11: 69,801,088 (GRCm39) |
V1153E |
probably damaging |
Het |
| Nkx2-1 |
A |
C |
12: 56,581,587 (GRCm39) |
C87G |
probably damaging |
Het |
| Nsun7 |
T |
C |
5: 66,436,000 (GRCm39) |
S291P |
probably damaging |
Het |
| Or10n1 |
A |
T |
9: 39,525,790 (GRCm39) |
Q309L |
probably benign |
Het |
| Or13a18 |
A |
T |
7: 140,190,373 (GRCm39) |
N90I |
possibly damaging |
Het |
| Or1p1c |
A |
T |
11: 74,160,550 (GRCm39) |
I112F |
probably damaging |
Het |
| Or4e1 |
G |
A |
14: 52,700,945 (GRCm39) |
P174S |
probably damaging |
Het |
| Or7g17 |
T |
A |
9: 18,768,632 (GRCm39) |
M237K |
probably benign |
Het |
| Pals1 |
G |
A |
12: 78,844,006 (GRCm39) |
R70H |
probably damaging |
Het |
| Pbrm1 |
A |
G |
14: 30,767,379 (GRCm39) |
Y331C |
possibly damaging |
Het |
| Pirb |
T |
A |
7: 3,719,273 (GRCm39) |
T539S |
probably benign |
Het |
| Plch2 |
T |
G |
4: 155,068,685 (GRCm39) |
T1314P |
probably benign |
Het |
| Polk |
T |
C |
13: 96,644,728 (GRCm39) |
S133G |
probably benign |
Het |
| Pramel27 |
A |
G |
4: 143,578,399 (GRCm39) |
I220V |
probably damaging |
Het |
| Prdm5 |
A |
T |
6: 65,904,967 (GRCm39) |
K533* |
probably null |
Het |
| Prmt1 |
T |
A |
7: 44,632,997 (GRCm39) |
Q35H |
probably benign |
Het |
| Pum3 |
A |
T |
19: 27,401,625 (GRCm39) |
W142R |
probably damaging |
Het |
| Rest |
G |
A |
5: 77,430,455 (GRCm39) |
R958H |
probably benign |
Het |
| Rictor |
C |
T |
15: 6,798,782 (GRCm39) |
T343M |
probably damaging |
Het |
| Ripor2 |
G |
A |
13: 24,855,886 (GRCm39) |
G109R |
probably damaging |
Het |
| Sec62 |
C |
T |
3: 30,872,978 (GRCm39) |
Q354* |
probably null |
Het |
| Snx14 |
T |
C |
9: 88,263,844 (GRCm39) |
Y847C |
probably damaging |
Het |
| Sox7 |
A |
T |
14: 64,185,438 (GRCm39) |
D158V |
probably benign |
Het |
| Spag8 |
A |
G |
4: 43,652,034 (GRCm39) |
V350A |
possibly damaging |
Het |
| Syngr1 |
A |
T |
15: 79,995,934 (GRCm39) |
I158F |
probably damaging |
Het |
| Tacstd2 |
C |
A |
6: 67,511,979 (GRCm39) |
V238L |
probably benign |
Het |
| Tex15 |
T |
C |
8: 34,063,014 (GRCm39) |
S815P |
possibly damaging |
Het |
| Tmem117 |
A |
T |
15: 94,612,793 (GRCm39) |
T110S |
possibly damaging |
Het |
| Trim30b |
C |
A |
7: 104,006,569 (GRCm39) |
V96L |
probably benign |
Het |
| Tssk3 |
TGCTATCATGGGG |
TG |
4: 129,383,106 (GRCm39) |
|
probably null |
Het |
| Tyk2 |
G |
T |
9: 21,031,822 (GRCm39) |
H418N |
probably benign |
Het |
| Uap1 |
G |
T |
1: 169,986,472 (GRCm39) |
T170K |
probably damaging |
Het |
| Vmn1r40 |
T |
C |
6: 89,691,606 (GRCm39) |
V141A |
not run |
Het |
| Vmn1r54 |
T |
A |
6: 90,246,647 (GRCm39) |
I187K |
probably damaging |
Het |
| Vmp1 |
C |
T |
11: 86,492,859 (GRCm39) |
V317M |
probably damaging |
Het |
| Wnt8b |
A |
G |
19: 44,500,511 (GRCm39) |
K366R |
probably benign |
Het |
| Zfp207 |
C |
T |
11: 80,286,004 (GRCm39) |
P415L |
unknown |
Het |
| Zfp263 |
A |
G |
16: 3,562,435 (GRCm39) |
E66G |
probably damaging |
Het |
| Zfp764l1 |
A |
G |
7: 126,990,695 (GRCm39) |
S431P |
probably benign |
Het |
| Zfp985 |
T |
A |
4: 147,667,913 (GRCm39) |
H260Q |
probably damaging |
Het |
| Zmiz1 |
GCC |
GC |
14: 25,576,624 (GRCm39) |
|
probably null |
Het |
| Zmiz1 |
A |
G |
14: 25,576,633 (GRCm39) |
R47G |
probably damaging |
Het |
| Zmiz1 |
A |
C |
14: 25,576,631 (GRCm39) |
Q46P |
probably damaging |
Het |
|
| Other mutations in Tnrc6a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00335:Tnrc6a
|
APN |
7 |
122,770,003 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL00580:Tnrc6a
|
APN |
7 |
122,773,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01309:Tnrc6a
|
APN |
7 |
122,770,717 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02004:Tnrc6a
|
APN |
7 |
122,780,589 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
IGL02142:Tnrc6a
|
APN |
7 |
122,751,414 (GRCm39) |
intron |
probably benign |
|
|
IGL02220:Tnrc6a
|
APN |
7 |
122,769,679 (GRCm39) |
missense |
probably benign |
|
|
IGL02436:Tnrc6a
|
APN |
7 |
122,783,438 (GRCm39) |
nonsense |
probably null |
|
|
IGL02670:Tnrc6a
|
APN |
7 |
122,770,535 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02743:Tnrc6a
|
APN |
7 |
122,770,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
0152:Tnrc6a
|
UTSW |
7 |
122,779,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0008:Tnrc6a
|
UTSW |
7 |
122,769,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0008:Tnrc6a
|
UTSW |
7 |
122,769,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0369:Tnrc6a
|
UTSW |
7 |
122,770,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0512:Tnrc6a
|
UTSW |
7 |
122,785,951 (GRCm39) |
splice site |
probably benign |
|
|
R0566:Tnrc6a
|
UTSW |
7 |
122,770,136 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0600:Tnrc6a
|
UTSW |
7 |
122,771,039 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0751:Tnrc6a
|
UTSW |
7 |
122,769,563 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1184:Tnrc6a
|
UTSW |
7 |
122,769,563 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1319:Tnrc6a
|
UTSW |
7 |
122,783,474 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1405:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1405:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1585:Tnrc6a
|
UTSW |
7 |
122,776,098 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1709:Tnrc6a
|
UTSW |
7 |
122,769,205 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1776:Tnrc6a
|
UTSW |
7 |
122,770,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1791:Tnrc6a
|
UTSW |
7 |
122,792,140 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1807:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R1876:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R2010:Tnrc6a
|
UTSW |
7 |
122,770,269 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2086:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R2089:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2091:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2091:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2511:Tnrc6a
|
UTSW |
7 |
122,770,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2830:Tnrc6a
|
UTSW |
7 |
122,792,172 (GRCm39) |
makesense |
probably null |
|
|
R2850:Tnrc6a
|
UTSW |
7 |
122,779,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3916:Tnrc6a
|
UTSW |
7 |
122,780,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4028:Tnrc6a
|
UTSW |
7 |
122,769,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4235:Tnrc6a
|
UTSW |
7 |
122,770,903 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4439:Tnrc6a
|
UTSW |
7 |
122,751,405 (GRCm39) |
nonsense |
probably null |
|
|
R4525:Tnrc6a
|
UTSW |
7 |
122,779,005 (GRCm39) |
missense |
probably benign |
|
|
R4578:Tnrc6a
|
UTSW |
7 |
122,783,444 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4613:Tnrc6a
|
UTSW |
7 |
122,783,512 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4711:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4722:Tnrc6a
|
UTSW |
7 |
122,791,313 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4746:Tnrc6a
|
UTSW |
7 |
122,789,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4892:Tnrc6a
|
UTSW |
7 |
122,769,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Tnrc6a
|
UTSW |
7 |
122,791,836 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4967:Tnrc6a
|
UTSW |
7 |
122,789,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5064:Tnrc6a
|
UTSW |
7 |
122,785,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5239:Tnrc6a
|
UTSW |
7 |
122,785,842 (GRCm39) |
missense |
probably benign |
|
|
R5604:Tnrc6a
|
UTSW |
7 |
122,773,459 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5805:Tnrc6a
|
UTSW |
7 |
122,769,299 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5942:Tnrc6a
|
UTSW |
7 |
122,785,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5988:Tnrc6a
|
UTSW |
7 |
122,781,603 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6212:Tnrc6a
|
UTSW |
7 |
122,742,965 (GRCm39) |
splice site |
probably null |
|
|
R6284:Tnrc6a
|
UTSW |
7 |
122,770,558 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6417:Tnrc6a
|
UTSW |
7 |
122,770,297 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6420:Tnrc6a
|
UTSW |
7 |
122,770,297 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6575:Tnrc6a
|
UTSW |
7 |
122,769,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6760:Tnrc6a
|
UTSW |
7 |
122,771,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6886:Tnrc6a
|
UTSW |
7 |
122,786,668 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6968:Tnrc6a
|
UTSW |
7 |
122,781,650 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7260:Tnrc6a
|
UTSW |
7 |
122,785,813 (GRCm39) |
missense |
probably benign |
0.36 |
|
R7299:Tnrc6a
|
UTSW |
7 |
122,770,136 (GRCm39) |
missense |
probably benign |
|
|
R7322:Tnrc6a
|
UTSW |
7 |
122,770,731 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7500:Tnrc6a
|
UTSW |
7 |
122,772,673 (GRCm39) |
splice site |
probably null |
|
|
R7872:Tnrc6a
|
UTSW |
7 |
122,779,057 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8270:Tnrc6a
|
UTSW |
7 |
122,769,294 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8313:Tnrc6a
|
UTSW |
7 |
122,769,936 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8348:Tnrc6a
|
UTSW |
7 |
122,791,346 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8390:Tnrc6a
|
UTSW |
7 |
122,761,794 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8448:Tnrc6a
|
UTSW |
7 |
122,791,346 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8514:Tnrc6a
|
UTSW |
7 |
122,783,438 (GRCm39) |
nonsense |
probably null |
|
|
R8552:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R8767:Tnrc6a
|
UTSW |
7 |
122,783,133 (GRCm39) |
unclassified |
probably benign |
|
|
R9047:Tnrc6a
|
UTSW |
7 |
122,778,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9147:Tnrc6a
|
UTSW |
7 |
122,785,667 (GRCm39) |
intron |
probably benign |
|
|
R9153:Tnrc6a
|
UTSW |
7 |
122,773,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9166:Tnrc6a
|
UTSW |
7 |
122,786,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9179:Tnrc6a
|
UTSW |
7 |
122,791,881 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9192:Tnrc6a
|
UTSW |
7 |
122,789,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Tnrc6a
|
UTSW |
7 |
122,778,958 (GRCm39) |
missense |
probably benign |
0.24 |
|
R9778:Tnrc6a
|
UTSW |
7 |
122,769,635 (GRCm39) |
missense |
probably benign |
0.43 |
|
X0064:Tnrc6a
|
UTSW |
7 |
122,769,021 (GRCm39) |
missense |
probably benign |
0.28 |
|
Z1176:Tnrc6a
|
UTSW |
7 |
122,761,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATACCTCATCTGTATCAGGGTGG -3'
(R):5'- CCCATCCCGATGAGTTATTTGG -3'
Sequencing Primer
(F):5'- GTGATCCCAAACCTACTCTGAGGTG -3'
(R):5'- ACCAGAAATGGACCTGTC -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation