Incidental Mutation 'R7221:Kirrel1'
| ID |
561797 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kirrel1
|
| Ensembl Gene |
ENSMUSG00000041734 |
| Gene Name |
kirre like nephrin family adhesion molecule 1 |
| Synonyms |
6720469N11Rik, Neph1, Kirrel1, Kirrel |
| MMRRC Submission |
045293-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7221 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
86985900-87082054 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
G to A
at 86993704 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Stop codon
at position 518
(Q518*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125525
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041732]
[ENSMUST00000107618]
[ENSMUST00000159976]
|
| AlphaFold |
Q80W68 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000041732
AA Change: Q518*
|
| SMART Domains |
Protein: ENSMUSP00000043756
Gene: ENSMUSG00000041734
AA Change: Q518*
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000107618
AA Change: Q518*
|
| SMART Domains |
Protein: ENSMUSP00000103243
Gene: ENSMUSG00000041734
AA Change: Q518*
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000159976
AA Change: Q518*
|
| SMART Domains |
Protein: ENSMUSP00000125525
Gene: ENSMUSG00000041734
AA Change: Q518*
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
100% (77/77) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a gene trap insertion exhibit postnatal lethality and are small and sickly. Glomerular and tubular defects in the kidney result in severe proteinuria. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(121) : Targeted, other(2) Gene trapped(119) |
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl2fm1 |
A |
G |
3: 59,836,354 (GRCm39) |
|
probably benign |
Het |
| Abr |
A |
C |
11: 76,313,987 (GRCm39) |
M720R |
probably benign |
Het |
| Acad10 |
G |
A |
5: 121,768,273 (GRCm39) |
T761M |
probably damaging |
Het |
| Agxt |
G |
T |
1: 93,065,623 (GRCm39) |
G164V |
possibly damaging |
Het |
| Ankar |
C |
T |
1: 72,689,390 (GRCm39) |
G1247D |
probably damaging |
Het |
| Bptf |
A |
C |
11: 106,945,658 (GRCm39) |
L2527R |
probably damaging |
Het |
| Brinp2 |
T |
C |
1: 158,094,117 (GRCm39) |
H195R |
possibly damaging |
Het |
| Cacna2d4 |
G |
T |
6: 119,213,624 (GRCm39) |
R14S |
probably benign |
Het |
| Cep126 |
A |
T |
9: 8,100,988 (GRCm39) |
C515* |
probably null |
Het |
| Chia1 |
A |
T |
3: 106,039,236 (GRCm39) |
N442I |
probably damaging |
Het |
| Clasp2 |
A |
G |
9: 113,681,825 (GRCm39) |
D327G |
probably damaging |
Het |
| Cnbd2 |
T |
C |
2: 156,215,581 (GRCm39) |
F519L |
probably benign |
Het |
| Cntrl |
T |
A |
2: 35,041,869 (GRCm39) |
F1214I |
possibly damaging |
Het |
| Cul9 |
A |
T |
17: 46,839,491 (GRCm39) |
M829K |
probably damaging |
Het |
| Cyp4b1 |
T |
C |
4: 115,493,175 (GRCm39) |
Q223R |
possibly damaging |
Het |
| Defb37 |
A |
T |
8: 19,040,988 (GRCm39) |
M1K |
probably null |
Het |
| Dnah7c |
A |
T |
1: 46,494,937 (GRCm39) |
Q55L |
possibly damaging |
Het |
| Efcab3 |
A |
G |
11: 104,791,432 (GRCm39) |
N2882S |
probably benign |
Het |
| Eif2b4 |
A |
T |
5: 31,345,131 (GRCm39) |
D463E |
possibly damaging |
Het |
| Elapor1 |
T |
G |
3: 108,382,317 (GRCm39) |
D232A |
possibly damaging |
Het |
| Elovl1 |
C |
T |
4: 118,288,811 (GRCm39) |
H167Y |
probably damaging |
Het |
| Emb |
T |
A |
13: 117,404,013 (GRCm39) |
L255Q |
probably damaging |
Het |
| Eogt |
T |
C |
6: 97,089,685 (GRCm39) |
Y465C |
probably damaging |
Het |
| Erc2 |
A |
G |
14: 27,375,115 (GRCm39) |
H111R |
probably damaging |
Het |
| Fam234b |
T |
C |
6: 135,205,529 (GRCm39) |
F498S |
probably damaging |
Het |
| Fgfr3 |
GAGGCTGGCAGCGTGTACGCAGGC |
GAGGC |
5: 33,890,092 (GRCm39) |
|
probably null |
Het |
| Flrt3 |
T |
A |
2: 140,503,090 (GRCm39) |
E179D |
probably damaging |
Het |
| Fndc3a |
T |
C |
14: 72,793,597 (GRCm39) |
R993G |
probably benign |
Het |
| Gm14325 |
T |
C |
2: 177,476,403 (GRCm39) |
T14A |
probably damaging |
Het |
| Gm5464 |
T |
A |
14: 67,106,681 (GRCm39) |
V106D |
unknown |
Het |
| Gpatch11 |
T |
A |
17: 79,149,546 (GRCm39) |
I182N |
possibly damaging |
Het |
| Grm6 |
A |
G |
11: 50,753,870 (GRCm39) |
R725G |
probably damaging |
Het |
| Hap1 |
A |
T |
11: 100,239,655 (GRCm39) |
M588K |
probably benign |
Het |
| Icam2 |
A |
G |
11: 106,273,268 (GRCm39) |
F15L |
probably benign |
Het |
| Ints8 |
A |
G |
4: 11,225,613 (GRCm39) |
M648T |
probably benign |
Het |
| Ipo11 |
A |
T |
13: 107,029,065 (GRCm39) |
L296Q |
probably damaging |
Het |
| Krt18 |
G |
T |
15: 101,937,967 (GRCm39) |
D155Y |
possibly damaging |
Het |
| Lctl |
A |
T |
9: 64,026,217 (GRCm39) |
K91* |
probably null |
Het |
| Marf1 |
C |
A |
16: 13,960,349 (GRCm39) |
R565L |
probably damaging |
Het |
| Med13 |
A |
T |
11: 86,178,921 (GRCm39) |
D1458E |
probably benign |
Het |
| Mroh8 |
T |
A |
2: 157,071,837 (GRCm39) |
Y556F |
probably benign |
Het |
| Muc16 |
C |
T |
9: 18,553,495 (GRCm39) |
G4266D |
probably benign |
Het |
| Nsrp1 |
A |
T |
11: 76,939,249 (GRCm39) |
F182I |
probably damaging |
Het |
| Obox3 |
A |
T |
7: 15,359,983 (GRCm39) |
Y229N |
probably benign |
Het |
| Or11h7 |
A |
T |
14: 50,891,528 (GRCm39) |
Y278F |
probably damaging |
Het |
| Or2b2 |
T |
C |
13: 21,887,272 (GRCm39) |
S34P |
probably damaging |
Het |
| Or2b4 |
A |
G |
17: 38,116,452 (GRCm39) |
K139E |
probably benign |
Het |
| Or4a74 |
T |
C |
2: 89,440,272 (GRCm39) |
Y58C |
probably damaging |
Het |
| Or4c108 |
A |
G |
2: 88,803,497 (GRCm39) |
V246A |
probably damaging |
Het |
| Or4p22 |
T |
A |
2: 88,317,973 (GRCm39) |
V299D |
probably damaging |
Het |
| Or8d1 |
A |
G |
9: 38,766,538 (GRCm39) |
Y60C |
probably damaging |
Het |
| Pabpc2 |
T |
A |
18: 39,906,963 (GRCm39) |
V76D |
possibly damaging |
Het |
| Parp9 |
T |
C |
16: 35,774,071 (GRCm39) |
W348R |
probably benign |
Het |
| Pdp1 |
T |
C |
4: 11,961,004 (GRCm39) |
T455A |
probably damaging |
Het |
| Phactr2 |
A |
C |
10: 13,122,783 (GRCm39) |
D446E |
possibly damaging |
Het |
| Pi4kb |
T |
C |
3: 94,901,500 (GRCm39) |
L389P |
probably damaging |
Het |
| Pla2g4f |
C |
T |
2: 120,131,476 (GRCm39) |
R749H |
probably benign |
Het |
| Plec |
A |
G |
15: 76,059,974 (GRCm39) |
V3321A |
probably damaging |
Het |
| Plod2 |
T |
C |
9: 92,466,580 (GRCm39) |
V180A |
probably damaging |
Het |
| Plppr5 |
A |
G |
3: 117,414,618 (GRCm39) |
I80V |
probably damaging |
Het |
| Potefam3d |
T |
G |
8: 69,975,316 (GRCm39) |
D50A |
probably benign |
Het |
| Rubcn |
T |
C |
16: 32,687,293 (GRCm39) |
|
probably null |
Het |
| Sacs |
T |
C |
14: 61,446,255 (GRCm39) |
V2767A |
probably damaging |
Het |
| Selenbp2 |
C |
G |
3: 94,611,133 (GRCm39) |
Y414* |
probably null |
Het |
| Slc45a4 |
A |
T |
15: 73,458,259 (GRCm39) |
M430K |
probably benign |
Het |
| Smg1 |
A |
G |
7: 117,782,020 (GRCm39) |
L1145P |
possibly damaging |
Het |
| Spns2 |
A |
G |
11: 72,347,742 (GRCm39) |
V316A |
probably benign |
Het |
| Srl |
T |
A |
16: 4,300,811 (GRCm39) |
E753D |
probably damaging |
Het |
| Thada |
T |
C |
17: 84,771,794 (GRCm39) |
T23A |
possibly damaging |
Het |
| Tmem231 |
T |
C |
8: 112,660,308 (GRCm39) |
T31A |
probably benign |
Het |
| Tpr |
C |
T |
1: 150,321,929 (GRCm39) |
T2321M |
possibly damaging |
Het |
| Ttn |
T |
A |
2: 76,772,195 (GRCm39) |
N2615I |
unknown |
Het |
| Vmn1r41 |
A |
G |
6: 89,724,034 (GRCm39) |
I192V |
probably benign |
Het |
| Vmn2r83 |
A |
T |
10: 79,316,001 (GRCm39) |
T466S |
probably benign |
Het |
| Vnn1 |
A |
G |
10: 23,770,952 (GRCm39) |
D60G |
probably benign |
Het |
| Wiz |
G |
A |
17: 32,578,139 (GRCm39) |
P449S |
probably benign |
Het |
| Zic1 |
A |
G |
9: 91,246,785 (GRCm39) |
S96P |
probably damaging |
Het |
| Zw10 |
T |
A |
9: 48,981,012 (GRCm39) |
S471T |
probably benign |
Het |
|
| Other mutations in Kirrel1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01310:Kirrel1
|
APN |
3 |
86,997,182 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL01865:Kirrel1
|
APN |
3 |
86,993,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01875:Kirrel1
|
APN |
3 |
87,003,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02337:Kirrel1
|
APN |
3 |
86,996,519 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL02724:Kirrel1
|
APN |
3 |
86,997,780 (GRCm39) |
nonsense |
probably null |
|
|
IGL02825:Kirrel1
|
APN |
3 |
86,996,595 (GRCm39) |
splice site |
probably benign |
|
|
IGL02826:Kirrel1
|
APN |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03102:Kirrel1
|
APN |
3 |
86,990,807 (GRCm39) |
missense |
probably damaging |
0.98 |
|
D4043:Kirrel1
|
UTSW |
3 |
86,990,510 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0360:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0364:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0421:Kirrel1
|
UTSW |
3 |
86,990,914 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0503:Kirrel1
|
UTSW |
3 |
87,005,109 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1112:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1116:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1144:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1190:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1226:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1501:Kirrel1
|
UTSW |
3 |
86,997,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1538:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1546:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1628:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1630:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1631:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1664:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1671:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1695:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1769:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1807:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1808:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1840:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1995:Kirrel1
|
UTSW |
3 |
87,003,093 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2014:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2086:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2108:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2354:Kirrel1
|
UTSW |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2407:Kirrel1
|
UTSW |
3 |
86,992,150 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2904:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2905:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2958:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2959:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2960:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2961:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3026:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3028:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3034:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R3149:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3195:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3196:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3499:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3699:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3720:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3721:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3788:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3793:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3877:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3901:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3910:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3911:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3912:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3913:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3930:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3931:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4022:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4067:Kirrel1
|
UTSW |
3 |
86,995,774 (GRCm39) |
nonsense |
probably null |
|
|
R4077:Kirrel1
|
UTSW |
3 |
86,992,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4198:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4328:Kirrel1
|
UTSW |
3 |
86,992,081 (GRCm39) |
intron |
probably benign |
|
|
R4355:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4363:Kirrel1
|
UTSW |
3 |
86,997,792 (GRCm39) |
nonsense |
probably null |
|
|
R4378:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4386:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4460:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4468:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4469:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4650:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4652:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4734:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4748:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4749:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R5304:Kirrel1
|
UTSW |
3 |
86,996,902 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5534:Kirrel1
|
UTSW |
3 |
86,997,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5604:Kirrel1
|
UTSW |
3 |
86,996,462 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7199:Kirrel1
|
UTSW |
3 |
86,990,695 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7284:Kirrel1
|
UTSW |
3 |
86,990,694 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7332:Kirrel1
|
UTSW |
3 |
86,995,705 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7369:Kirrel1
|
UTSW |
3 |
87,048,391 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7371:Kirrel1
|
UTSW |
3 |
86,995,729 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7508:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R7566:Kirrel1
|
UTSW |
3 |
86,995,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7567:Kirrel1
|
UTSW |
3 |
87,002,988 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7621:Kirrel1
|
UTSW |
3 |
86,995,528 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8030:Kirrel1
|
UTSW |
3 |
87,005,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8141:Kirrel1
|
UTSW |
3 |
86,993,735 (GRCm39) |
nonsense |
probably null |
|
|
R8261:Kirrel1
|
UTSW |
3 |
86,995,309 (GRCm39) |
intron |
probably benign |
|
|
R8477:Kirrel1
|
UTSW |
3 |
86,992,138 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8512:Kirrel1
|
UTSW |
3 |
86,995,534 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8954:Kirrel1
|
UTSW |
3 |
86,997,173 (GRCm39) |
missense |
probably benign |
0.25 |
|
R8987:Kirrel1
|
UTSW |
3 |
86,992,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9058:Kirrel1
|
UTSW |
3 |
86,992,442 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9146:Kirrel1
|
UTSW |
3 |
87,003,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9311:Kirrel1
|
UTSW |
3 |
87,005,123 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9527:Kirrel1
|
UTSW |
3 |
86,996,912 (GRCm39) |
nonsense |
probably null |
|
|
R9629:Kirrel1
|
UTSW |
3 |
87,003,025 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Kirrel1
|
UTSW |
3 |
86,991,182 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GATGGCTTTCTGTTCATGCC -3'
(R):5'- ATGAGCTTCTTCCACGCATC -3'
Sequencing Primer
(F):5'- ATGCCTACAACTGTTCCTTCAAAG -3'
(R):5'- TCCCCCATCCCAGGCATG -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation