Incidental Mutation 'R7223:Tet1'
| ID |
561952 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tet1
|
| Ensembl Gene |
ENSMUSG00000047146 |
| Gene Name |
tet methylcytosine dioxygenase 1 |
| Synonyms |
BB001228, 2510010B09Rik, D10Ertd17e, Cxxc6 |
| MMRRC Submission |
045295-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7223 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
62804570-62908996 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 62813671 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Aspartic acid
at position 87
(N87D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000134328
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000050826]
[ENSMUST00000174121]
[ENSMUST00000174189]
|
| AlphaFold |
Q3URK3 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000050826
AA Change: N1684D
PolyPhen 2
Score 0.886 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000059527
Gene: ENSMUSG00000047146
AA Change: N1684D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
21 |
N/A |
INTRINSIC |
|
low complexity region
|
118 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
553 |
564 |
N/A |
INTRINSIC |
|
Pfam:zf-CXXC
|
566 |
607 |
2.5e-11 |
PFAM |
|
low complexity region
|
884 |
902 |
N/A |
INTRINSIC |
|
low complexity region
|
1087 |
1106 |
N/A |
INTRINSIC |
|
Tet_JBP
|
1528 |
1931 |
1e-171 |
SMART |
|
low complexity region
|
1944 |
1956 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000133706
Gene: ENSMUSG00000047146
AA Change: N86D
| Domain | Start | End | E-Value | Type |
|---|
|
Tet_JBP
|
2 |
138 |
2.64e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000173905
|
| SMART Domains |
Protein: ENSMUSP00000134571
Gene: ENSMUSG00000047146
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Tet_JBP
|
1 |
61 |
2.4e-20 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000174121
AA Change: N87D
PolyPhen 2
Score 0.953 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000134328
Gene: ENSMUSG00000047146
AA Change: N87D
| Domain | Start | End | E-Value | Type |
|---|
|
Tet_JBP
|
1 |
352 |
1.49e-83 |
SMART |
|
low complexity region
|
365 |
377 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000174189
AA Change: N1716D
PolyPhen 2
Score 0.896 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000133279
Gene: ENSMUSG00000047146
AA Change: N1716D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
21 |
N/A |
INTRINSIC |
|
low complexity region
|
118 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
553 |
564 |
N/A |
INTRINSIC |
|
Pfam:zf-CXXC
|
566 |
607 |
2.7e-10 |
PFAM |
|
low complexity region
|
884 |
902 |
N/A |
INTRINSIC |
|
low complexity region
|
1087 |
1106 |
N/A |
INTRINSIC |
|
Tet_JBP
|
1528 |
1963 |
7.36e-170 |
SMART |
|
low complexity region
|
1976 |
1988 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] DNA methylation is an epigenetic mechanism that is important for controlling gene expression. The protein encoded by this gene is a demethylase that belongs to the TET (ten-eleven translocation) family. Members of the TET protein family play a role in the DNA methylation process and gene activation. [provided by RefSeq, Sep 2015]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit background sensitive lethality, abnormal forebrain development, abnormal female reproductive organs and decreased litter size. Mice homozygous for a different knock-out allele exhibit impaired adult neurogenesis, impaired spatial learning and impaired short-term memory retention. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb11 |
A |
T |
2: 69,274,143 (GRCm38) |
V733E |
probably benign |
Het |
| Adam34 |
A |
T |
8: 43,652,004 (GRCm38) |
N201K |
probably benign |
Het |
| Aldh3b2 |
A |
C |
19: 3,979,592 (GRCm38) |
S322R |
probably damaging |
Het |
| Anpep |
A |
T |
7: 79,825,310 (GRCm38) |
L914Q |
probably damaging |
Het |
| Arhgap30 |
T |
C |
1: 171,407,571 (GRCm38) |
F535S |
probably damaging |
Het |
| Baiap3 |
G |
A |
17: 25,243,840 (GRCm38) |
R1075C |
probably benign |
Het |
| Baz2a |
G |
T |
10: 128,112,606 (GRCm38) |
G252V |
probably damaging |
Het |
| Brinp3 |
T |
A |
1: 146,901,074 (GRCm38) |
S420T |
possibly damaging |
Het |
| Carmil3 |
T |
C |
14: 55,496,238 (GRCm38) |
F359S |
possibly damaging |
Het |
| Ccdc124 |
A |
T |
8: 70,868,526 (GRCm38) |
L190Q |
probably damaging |
Het |
| Ccr6 |
T |
C |
17: 8,256,140 (GRCm38) |
V59A |
probably damaging |
Het |
| Ccr8 |
T |
A |
9: 120,094,617 (GRCm38) |
I266N |
probably damaging |
Het |
| Cdh23 |
T |
A |
10: 60,331,817 (GRCm38) |
E1798V |
probably damaging |
Het |
| Cdk5rap2 |
T |
C |
4: 70,235,447 (GRCm38) |
N1713S |
probably benign |
Het |
| Cep19 |
T |
A |
16: 32,104,015 (GRCm38) |
I33N |
probably damaging |
Het |
| Cers3 |
A |
T |
7: 66,783,415 (GRCm38) |
Y196F |
probably damaging |
Het |
| Cidea |
T |
C |
18: 67,366,421 (GRCm38) |
I126T |
probably damaging |
Het |
| Copg2 |
A |
T |
6: 30,812,754 (GRCm38) |
Y546* |
probably null |
Het |
| Cul3 |
A |
T |
1: 80,287,000 (GRCm38) |
V261E |
probably benign |
Het |
| Cyp2g1 |
A |
T |
7: 26,814,632 (GRCm38) |
D221V |
probably damaging |
Het |
| Cyp8b1 |
G |
A |
9: 121,915,097 (GRCm38) |
H390Y |
probably damaging |
Het |
| Daam1 |
T |
C |
12: 71,988,943 (GRCm38) |
F971L |
probably damaging |
Het |
| Dnajc24 |
G |
A |
2: 106,001,966 (GRCm38) |
S24L |
possibly damaging |
Het |
| Dpysl3 |
T |
C |
18: 43,438,042 (GRCm38) |
S56G |
probably benign |
Het |
| Esp1 |
A |
G |
17: 40,731,081 (GRCm38) |
D88G |
probably benign |
Het |
| Fam171b |
A |
G |
2: 83,878,230 (GRCm38) |
T359A |
probably damaging |
Het |
| Fam186b |
T |
C |
15: 99,279,837 (GRCm38) |
E536G |
possibly damaging |
Het |
| Fbxo3 |
T |
C |
2: 104,043,012 (GRCm38) |
V156A |
possibly damaging |
Het |
| Gls2 |
C |
A |
10: 128,199,194 (GRCm38) |
H65Q |
probably benign |
Het |
| Gp2 |
A |
G |
7: 119,451,498 (GRCm38) |
|
probably null |
Het |
| Gpcpd1 |
T |
A |
2: 132,534,056 (GRCm38) |
K435I |
probably benign |
Het |
| Gpx6 |
T |
A |
13: 21,317,670 (GRCm38) |
|
probably null |
Het |
| Hps3 |
A |
T |
3: 20,030,419 (GRCm38) |
S202T |
probably benign |
Het |
| Htr1d |
T |
A |
4: 136,443,501 (GRCm38) |
L347H |
probably damaging |
Het |
| Igfals |
T |
C |
17: 24,881,234 (GRCm38) |
L433P |
probably damaging |
Het |
| Ilvbl |
C |
T |
10: 78,583,696 (GRCm38) |
H537Y |
probably benign |
Het |
| Iqgap2 |
A |
T |
13: 95,628,972 (GRCm38) |
M1530K |
probably damaging |
Het |
| Jarid2 |
A |
G |
13: 44,896,322 (GRCm38) |
T247A |
possibly damaging |
Het |
| L3hypdh |
C |
T |
12: 72,074,009 (GRCm38) |
V323I |
possibly damaging |
Het |
| Lama3 |
C |
T |
18: 12,582,608 (GRCm38) |
T1707I |
possibly damaging |
Het |
| Map6 |
G |
T |
7: 99,268,025 (GRCm38) |
A2S |
probably damaging |
Het |
| Mfap3 |
T |
A |
11: 57,530,240 (GRCm38) |
I349K |
probably benign |
Het |
| Mybl2 |
A |
G |
2: 163,072,705 (GRCm38) |
T248A |
probably benign |
Het |
| N6amt1 |
A |
G |
16: 87,362,660 (GRCm38) |
*151W |
probably null |
Het |
| Nhlrc1 |
A |
G |
13: 47,014,208 (GRCm38) |
V191A |
probably benign |
Het |
| Nkx2-5 |
T |
C |
17: 26,839,620 (GRCm38) |
E120G |
possibly damaging |
Het |
| Olfr1066 |
T |
A |
2: 86,455,867 (GRCm38) |
I135F |
possibly damaging |
Het |
| Olfr1380 |
T |
A |
11: 49,564,098 (GRCm38) |
M59K |
probably damaging |
Het |
| Olfr582 |
C |
A |
7: 103,041,632 (GRCm38) |
T46N |
possibly damaging |
Het |
| Olfr890 |
T |
C |
9: 38,143,753 (GRCm38) |
V201A |
probably benign |
Het |
| Pcdha8 |
T |
G |
18: 36,993,148 (GRCm38) |
L228V |
probably benign |
Het |
| Pcsk2 |
A |
G |
2: 143,690,333 (GRCm38) |
T134A |
possibly damaging |
Het |
| Phldb3 |
G |
A |
7: 24,624,653 (GRCm38) |
R484Q |
probably benign |
Het |
| Pipox |
A |
G |
11: 77,881,186 (GRCm38) |
S371P |
probably damaging |
Het |
| Plekhg1 |
T |
C |
10: 3,873,343 (GRCm38) |
S159P |
|
Het |
| Psme4 |
C |
T |
11: 30,874,226 (GRCm38) |
P1737S |
probably benign |
Het |
| Pygm |
G |
A |
19: 6,388,863 (GRCm38) |
D328N |
probably benign |
Het |
| Rabgef1 |
A |
T |
5: 130,190,960 (GRCm38) |
E88V |
probably benign |
Het |
| Rims2 |
G |
T |
15: 39,437,032 (GRCm38) |
R245L |
probably benign |
Het |
| Slc38a4 |
T |
C |
15: 97,010,345 (GRCm38) |
I172V |
probably damaging |
Het |
| Slc4a10 |
T |
A |
2: 62,268,665 (GRCm38) |
Y586N |
probably damaging |
Het |
| Snap91 |
C |
T |
9: 86,879,557 (GRCm38) |
|
probably benign |
Het |
| Sorcs1 |
C |
T |
19: 50,190,042 (GRCm38) |
V881I |
probably benign |
Het |
| Spef2 |
A |
T |
15: 9,601,640 (GRCm38) |
V1512E |
unknown |
Het |
| Sufu |
T |
C |
19: 46,453,277 (GRCm38) |
I292T |
possibly damaging |
Het |
| Tmem108 |
T |
C |
9: 103,499,534 (GRCm38) |
T239A |
not run |
Het |
| Tmem121 |
A |
T |
12: 113,188,494 (GRCm38) |
K111* |
probably null |
Het |
| Tpp2 |
T |
A |
1: 43,968,888 (GRCm38) |
D417E |
probably damaging |
Het |
| Tpr |
G |
A |
1: 150,439,256 (GRCm38) |
E2025K |
possibly damaging |
Het |
| Trappc3 |
C |
T |
4: 126,275,152 (GRCm38) |
A145V |
possibly damaging |
Het |
| Ttn |
T |
C |
2: 76,890,981 (GRCm38) |
D6754G |
probably null |
Het |
| Unc13c |
T |
A |
9: 73,629,191 (GRCm38) |
M1627L |
probably benign |
Het |
| Ush2a |
A |
G |
1: 188,810,217 (GRCm38) |
I3327V |
probably benign |
Het |
| Vmn1r74 |
C |
T |
7: 11,846,967 (GRCm38) |
Q65* |
probably null |
Het |
| Wdr18 |
G |
A |
10: 79,960,368 (GRCm38) |
R69H |
probably damaging |
Het |
| Zbed5 |
G |
T |
5: 129,900,438 (GRCm38) |
D132Y |
probably damaging |
Het |
| Zfp644 |
A |
T |
5: 106,637,582 (GRCm38) |
Y366* |
probably null |
Het |
| Zfyve26 |
T |
C |
12: 79,246,171 (GRCm38) |
N2068S |
probably damaging |
Het |
| Zic2 |
T |
C |
14: 122,476,091 (GRCm38) |
F139S |
probably damaging |
Het |
| Zmynd11 |
T |
C |
13: 9,710,162 (GRCm38) |
Q141R |
probably benign |
Het |
| Zrsr1 |
A |
G |
11: 22,973,388 (GRCm38) |
E54G |
probably benign |
Het |
| Zscan10 |
G |
A |
17: 23,609,482 (GRCm38) |
D333N |
probably benign |
Het |
|
| Other mutations in Tet1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00539:Tet1
|
APN |
10 |
62,814,497 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01079:Tet1
|
APN |
10 |
62,879,473 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01109:Tet1
|
APN |
10 |
62,879,774 (GRCm38) |
missense |
probably benign |
|
|
IGL01634:Tet1
|
APN |
10 |
62,878,588 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL02003:Tet1
|
APN |
10 |
62,816,400 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL02081:Tet1
|
APN |
10 |
62,813,818 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02100:Tet1
|
APN |
10 |
62,812,728 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL02228:Tet1
|
APN |
10 |
62,813,734 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02524:Tet1
|
APN |
10 |
62,878,646 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02539:Tet1
|
APN |
10 |
62,813,019 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
IGL02608:Tet1
|
APN |
10 |
62,839,087 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02608:Tet1
|
APN |
10 |
62,879,609 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
IGL02702:Tet1
|
APN |
10 |
62,879,752 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
K7371:Tet1
|
UTSW |
10 |
62,879,176 (GRCm38) |
missense |
probably benign |
|
|
R0166:Tet1
|
UTSW |
10 |
62,840,279 (GRCm38) |
missense |
probably benign |
0.05 |
|
R0371:Tet1
|
UTSW |
10 |
62,878,399 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R0373:Tet1
|
UTSW |
10 |
62,878,209 (GRCm38) |
nonsense |
probably null |
|
|
R0391:Tet1
|
UTSW |
10 |
62,814,546 (GRCm38) |
splice site |
probably null |
|
|
R0445:Tet1
|
UTSW |
10 |
62,879,941 (GRCm38) |
missense |
probably benign |
0.08 |
|
R1016:Tet1
|
UTSW |
10 |
62,879,950 (GRCm38) |
missense |
probably benign |
|
|
R1344:Tet1
|
UTSW |
10 |
62,814,521 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1546:Tet1
|
UTSW |
10 |
62,812,910 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1651:Tet1
|
UTSW |
10 |
62,879,674 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1725:Tet1
|
UTSW |
10 |
62,814,477 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1752:Tet1
|
UTSW |
10 |
62,812,989 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1834:Tet1
|
UTSW |
10 |
62,813,665 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1964:Tet1
|
UTSW |
10 |
62,812,947 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R2239:Tet1
|
UTSW |
10 |
62,879,734 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2962:Tet1
|
UTSW |
10 |
62,814,544 (GRCm38) |
nonsense |
probably null |
|
|
R3084:Tet1
|
UTSW |
10 |
62,879,621 (GRCm38) |
missense |
probably benign |
0.34 |
|
R3086:Tet1
|
UTSW |
10 |
62,879,621 (GRCm38) |
missense |
probably benign |
0.34 |
|
R3972:Tet1
|
UTSW |
10 |
62,813,726 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4622:Tet1
|
UTSW |
10 |
62,819,474 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4674:Tet1
|
UTSW |
10 |
62,838,848 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R4687:Tet1
|
UTSW |
10 |
62,838,791 (GRCm38) |
missense |
probably benign |
0.04 |
|
R4718:Tet1
|
UTSW |
10 |
62,813,812 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4801:Tet1
|
UTSW |
10 |
62,822,663 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4802:Tet1
|
UTSW |
10 |
62,822,663 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4903:Tet1
|
UTSW |
10 |
62,822,658 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5153:Tet1
|
UTSW |
10 |
62,878,578 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R5193:Tet1
|
UTSW |
10 |
62,838,247 (GRCm38) |
missense |
probably benign |
0.22 |
|
R5225:Tet1
|
UTSW |
10 |
62,838,671 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5437:Tet1
|
UTSW |
10 |
62,814,451 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5465:Tet1
|
UTSW |
10 |
62,839,777 (GRCm38) |
missense |
probably benign |
|
|
R5535:Tet1
|
UTSW |
10 |
62,832,907 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5586:Tet1
|
UTSW |
10 |
62,878,294 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5763:Tet1
|
UTSW |
10 |
62,840,068 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5788:Tet1
|
UTSW |
10 |
62,839,958 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R5818:Tet1
|
UTSW |
10 |
62,816,408 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R5860:Tet1
|
UTSW |
10 |
62,812,620 (GRCm38) |
splice site |
probably null |
|
|
R5975:Tet1
|
UTSW |
10 |
62,879,773 (GRCm38) |
missense |
probably benign |
0.37 |
|
R6041:Tet1
|
UTSW |
10 |
62,813,373 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6092:Tet1
|
UTSW |
10 |
62,813,715 (GRCm38) |
missense |
probably benign |
0.10 |
|
R6132:Tet1
|
UTSW |
10 |
62,813,300 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6157:Tet1
|
UTSW |
10 |
62,839,970 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6520:Tet1
|
UTSW |
10 |
62,880,013 (GRCm38) |
start codon destroyed |
probably null |
0.53 |
|
R7210:Tet1
|
UTSW |
10 |
62,814,501 (GRCm38) |
missense |
probably null |
0.95 |
|
R7255:Tet1
|
UTSW |
10 |
62,822,636 (GRCm38) |
missense |
probably benign |
0.15 |
|
R7323:Tet1
|
UTSW |
10 |
62,880,039 (GRCm38) |
start gained |
probably benign |
|
|
R7472:Tet1
|
UTSW |
10 |
62,813,350 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R7507:Tet1
|
UTSW |
10 |
62,832,892 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7522:Tet1
|
UTSW |
10 |
62,818,983 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R7849:Tet1
|
UTSW |
10 |
62,819,473 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R7879:Tet1
|
UTSW |
10 |
62,879,046 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8073:Tet1
|
UTSW |
10 |
62,813,353 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8098:Tet1
|
UTSW |
10 |
62,879,080 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8147:Tet1
|
UTSW |
10 |
62,878,807 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8355:Tet1
|
UTSW |
10 |
62,816,450 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R8545:Tet1
|
UTSW |
10 |
62,812,939 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8556:Tet1
|
UTSW |
10 |
62,840,206 (GRCm38) |
missense |
probably benign |
0.37 |
|
R8936:Tet1
|
UTSW |
10 |
62,840,284 (GRCm38) |
nonsense |
probably null |
|
|
R9173:Tet1
|
UTSW |
10 |
62,840,286 (GRCm38) |
missense |
probably benign |
|
|
R9414:Tet1
|
UTSW |
10 |
62,839,156 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9584:Tet1
|
UTSW |
10 |
62,819,527 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1177:Tet1
|
UTSW |
10 |
62,818,985 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCACTGGTAGTTCATAGACACAAAG -3'
(R):5'- AGAACAGGCCTTATTCCTCTCC -3'
Sequencing Primer
(F):5'- GTAGTTCATAGACACAAAGTTACACC -3'
(R):5'- CTGTCCCTCAGGTGTGTACG -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation