Incidental Mutation 'R7223:Iqgap2'
| ID |
561970 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Iqgap2
|
| Ensembl Gene |
ENSMUSG00000021676 |
| Gene Name |
IQ motif containing GTPase activating protein 2 |
| Synonyms |
4933417J23Rik |
| MMRRC Submission |
045295-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7223 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
95763685-96028788 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 95765480 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Lysine
at position 1530
(M1530K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000067685
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068603]
|
| AlphaFold |
Q3UQ44 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000068603
AA Change: M1530K
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000067685
Gene: ENSMUSG00000021676
AA Change: M1530K
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
43 |
152 |
3.32e-16 |
SMART |
|
coiled coil region
|
253 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
IQ
|
689 |
711 |
1.38e-4 |
SMART |
|
IQ
|
719 |
741 |
7.36e0 |
SMART |
|
IQ
|
749 |
771 |
2.43e1 |
SMART |
|
coiled coil region
|
799 |
828 |
N/A |
INTRINSIC |
|
RasGAP
|
905 |
1258 |
2.6e-120 |
SMART |
|
Pfam:RasGAP_C
|
1367 |
1498 |
3.2e-40 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a null mutation display reduced survival with increased incidence of hepatocellular carcinomas, increased hepatocyte apoptosis, and hepatocyte mitochondrial abnormalities. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb11 |
A |
T |
2: 69,104,487 (GRCm39) |
V733E |
probably benign |
Het |
| Adam34 |
A |
T |
8: 44,105,041 (GRCm39) |
N201K |
probably benign |
Het |
| Aldh3b2 |
A |
C |
19: 4,029,592 (GRCm39) |
S322R |
probably damaging |
Het |
| Anpep |
A |
T |
7: 79,475,058 (GRCm39) |
L914Q |
probably damaging |
Het |
| Arhgap30 |
T |
C |
1: 171,235,139 (GRCm39) |
F535S |
probably damaging |
Het |
| Baiap3 |
G |
A |
17: 25,462,814 (GRCm39) |
R1075C |
probably benign |
Het |
| Baz2a |
G |
T |
10: 127,948,475 (GRCm39) |
G252V |
probably damaging |
Het |
| Brinp3 |
T |
A |
1: 146,776,812 (GRCm39) |
S420T |
possibly damaging |
Het |
| Carmil3 |
T |
C |
14: 55,733,695 (GRCm39) |
F359S |
possibly damaging |
Het |
| Ccdc124 |
A |
T |
8: 71,321,170 (GRCm39) |
L190Q |
probably damaging |
Het |
| Ccr6 |
T |
C |
17: 8,474,972 (GRCm39) |
V59A |
probably damaging |
Het |
| Ccr8 |
T |
A |
9: 119,923,683 (GRCm39) |
I266N |
probably damaging |
Het |
| Cdh23 |
T |
A |
10: 60,167,596 (GRCm39) |
E1798V |
probably damaging |
Het |
| Cdk5rap2 |
T |
C |
4: 70,153,684 (GRCm39) |
N1713S |
probably benign |
Het |
| Cep19 |
T |
A |
16: 31,922,833 (GRCm39) |
I33N |
probably damaging |
Het |
| Cers3 |
A |
T |
7: 66,433,163 (GRCm39) |
Y196F |
probably damaging |
Het |
| Cidea |
T |
C |
18: 67,499,491 (GRCm39) |
I126T |
probably damaging |
Het |
| Copg2 |
A |
T |
6: 30,789,689 (GRCm39) |
Y546* |
probably null |
Het |
| Cul3 |
A |
T |
1: 80,264,717 (GRCm39) |
V261E |
probably benign |
Het |
| Cyp2g1 |
A |
T |
7: 26,514,057 (GRCm39) |
D221V |
probably damaging |
Het |
| Cyp8b1 |
G |
A |
9: 121,744,163 (GRCm39) |
H390Y |
probably damaging |
Het |
| Daam1 |
T |
C |
12: 72,035,717 (GRCm39) |
F971L |
probably damaging |
Het |
| Dnajc24 |
G |
A |
2: 105,832,311 (GRCm39) |
S24L |
possibly damaging |
Het |
| Dpysl3 |
T |
C |
18: 43,571,107 (GRCm39) |
S56G |
probably benign |
Het |
| Esp1 |
A |
G |
17: 41,041,972 (GRCm39) |
D88G |
probably benign |
Het |
| Fam171b |
A |
G |
2: 83,708,574 (GRCm39) |
T359A |
probably damaging |
Het |
| Fam186b |
T |
C |
15: 99,177,718 (GRCm39) |
E536G |
possibly damaging |
Het |
| Fbxo3 |
T |
C |
2: 103,873,357 (GRCm39) |
V156A |
possibly damaging |
Het |
| Gls2 |
C |
A |
10: 128,035,063 (GRCm39) |
H65Q |
probably benign |
Het |
| Gp2 |
A |
G |
7: 119,050,721 (GRCm39) |
|
probably null |
Het |
| Gpcpd1 |
T |
A |
2: 132,375,976 (GRCm39) |
K435I |
probably benign |
Het |
| Gpx6 |
T |
A |
13: 21,501,840 (GRCm39) |
|
probably null |
Het |
| Hps3 |
A |
T |
3: 20,084,583 (GRCm39) |
S202T |
probably benign |
Het |
| Htr1d |
T |
A |
4: 136,170,812 (GRCm39) |
L347H |
probably damaging |
Het |
| Igfals |
T |
C |
17: 25,100,208 (GRCm39) |
L433P |
probably damaging |
Het |
| Ilvbl |
C |
T |
10: 78,419,530 (GRCm39) |
H537Y |
probably benign |
Het |
| Jarid2 |
A |
G |
13: 45,049,798 (GRCm39) |
T247A |
possibly damaging |
Het |
| L3hypdh |
C |
T |
12: 72,120,783 (GRCm39) |
V323I |
possibly damaging |
Het |
| Lama3 |
C |
T |
18: 12,715,665 (GRCm39) |
T1707I |
possibly damaging |
Het |
| Map6 |
G |
T |
7: 98,917,232 (GRCm39) |
A2S |
probably damaging |
Het |
| Mfap3 |
T |
A |
11: 57,421,066 (GRCm39) |
I349K |
probably benign |
Het |
| Mybl2 |
A |
G |
2: 162,914,625 (GRCm39) |
T248A |
probably benign |
Het |
| N6amt1 |
A |
G |
16: 87,159,548 (GRCm39) |
*151W |
probably null |
Het |
| Nhlrc1 |
A |
G |
13: 47,167,684 (GRCm39) |
V191A |
probably benign |
Het |
| Nkx2-5 |
T |
C |
17: 27,058,594 (GRCm39) |
E120G |
possibly damaging |
Het |
| Or2y10 |
T |
A |
11: 49,454,925 (GRCm39) |
M59K |
probably damaging |
Het |
| Or52r1b |
C |
A |
7: 102,690,839 (GRCm39) |
T46N |
possibly damaging |
Het |
| Or8b41 |
T |
C |
9: 38,055,049 (GRCm39) |
V201A |
probably benign |
Het |
| Or8k28 |
T |
A |
2: 86,286,211 (GRCm39) |
I135F |
possibly damaging |
Het |
| Pcdha8 |
T |
G |
18: 37,126,201 (GRCm39) |
L228V |
probably benign |
Het |
| Pcsk2 |
A |
G |
2: 143,532,253 (GRCm39) |
T134A |
possibly damaging |
Het |
| Phldb3 |
G |
A |
7: 24,324,078 (GRCm39) |
R484Q |
probably benign |
Het |
| Pipox |
A |
G |
11: 77,772,012 (GRCm39) |
S371P |
probably damaging |
Het |
| Plekhg1 |
T |
C |
10: 3,823,343 (GRCm39) |
S159P |
|
Het |
| Psme4 |
C |
T |
11: 30,824,226 (GRCm39) |
P1737S |
probably benign |
Het |
| Pygm |
G |
A |
19: 6,438,893 (GRCm39) |
D328N |
probably benign |
Het |
| Rabgef1 |
A |
T |
5: 130,219,801 (GRCm39) |
E88V |
probably benign |
Het |
| Rims2 |
G |
T |
15: 39,300,428 (GRCm39) |
R245L |
probably benign |
Het |
| Slc38a4 |
T |
C |
15: 96,908,226 (GRCm39) |
I172V |
probably damaging |
Het |
| Slc4a10 |
T |
A |
2: 62,099,009 (GRCm39) |
Y586N |
probably damaging |
Het |
| Snap91 |
C |
T |
9: 86,761,610 (GRCm39) |
|
probably benign |
Het |
| Sorcs1 |
C |
T |
19: 50,178,480 (GRCm39) |
V881I |
probably benign |
Het |
| Spef2 |
A |
T |
15: 9,601,726 (GRCm39) |
V1512E |
unknown |
Het |
| Sufu |
T |
C |
19: 46,441,716 (GRCm39) |
I292T |
possibly damaging |
Het |
| Tet1 |
T |
C |
10: 62,649,450 (GRCm39) |
N87D |
possibly damaging |
Het |
| Tmem108 |
T |
C |
9: 103,376,733 (GRCm39) |
T239A |
not run |
Het |
| Tmem121 |
A |
T |
12: 113,152,114 (GRCm39) |
K111* |
probably null |
Het |
| Tpp2 |
T |
A |
1: 44,008,048 (GRCm39) |
D417E |
probably damaging |
Het |
| Tpr |
G |
A |
1: 150,315,007 (GRCm39) |
E2025K |
possibly damaging |
Het |
| Trappc3 |
C |
T |
4: 126,168,945 (GRCm39) |
A145V |
possibly damaging |
Het |
| Ttn |
T |
C |
2: 76,721,325 (GRCm39) |
D6754G |
probably null |
Het |
| Unc13c |
T |
A |
9: 73,536,473 (GRCm39) |
M1627L |
probably benign |
Het |
| Ush2a |
A |
G |
1: 188,542,414 (GRCm39) |
I3327V |
probably benign |
Het |
| Vmn1r74 |
C |
T |
7: 11,580,894 (GRCm39) |
Q65* |
probably null |
Het |
| Wdr18 |
G |
A |
10: 79,796,202 (GRCm39) |
R69H |
probably damaging |
Het |
| Zbed5 |
G |
T |
5: 129,929,279 (GRCm39) |
D132Y |
probably damaging |
Het |
| Zfp644 |
A |
T |
5: 106,785,448 (GRCm39) |
Y366* |
probably null |
Het |
| Zfyve26 |
T |
C |
12: 79,292,945 (GRCm39) |
N2068S |
probably damaging |
Het |
| Zic2 |
T |
C |
14: 122,713,503 (GRCm39) |
F139S |
probably damaging |
Het |
| Zmynd11 |
T |
C |
13: 9,760,198 (GRCm39) |
Q141R |
probably benign |
Het |
| Zrsr2-ps1 |
A |
G |
11: 22,923,388 (GRCm39) |
E54G |
probably benign |
Het |
| Zscan10 |
G |
A |
17: 23,828,456 (GRCm39) |
D333N |
probably benign |
Het |
|
| Other mutations in Iqgap2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00799:Iqgap2
|
APN |
13 |
95,794,452 (GRCm39) |
splice site |
probably benign |
|
|
IGL01968:Iqgap2
|
APN |
13 |
95,772,090 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02049:Iqgap2
|
APN |
13 |
95,811,913 (GRCm39) |
splice site |
probably benign |
|
|
IGL02195:Iqgap2
|
APN |
13 |
95,798,242 (GRCm39) |
splice site |
probably benign |
|
|
IGL02387:Iqgap2
|
APN |
13 |
95,826,209 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02634:Iqgap2
|
APN |
13 |
95,764,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02666:Iqgap2
|
APN |
13 |
95,764,564 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02685:Iqgap2
|
APN |
13 |
95,807,912 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02927:Iqgap2
|
APN |
13 |
95,861,184 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL02943:Iqgap2
|
APN |
13 |
95,798,243 (GRCm39) |
splice site |
probably benign |
|
|
IGL03167:Iqgap2
|
APN |
13 |
95,821,406 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL03169:Iqgap2
|
APN |
13 |
95,867,785 (GRCm39) |
splice site |
probably null |
|
|
IGL03293:Iqgap2
|
APN |
13 |
95,867,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
G1Funyon:Iqgap2
|
UTSW |
13 |
95,818,659 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0257:Iqgap2
|
UTSW |
13 |
95,861,052 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0335:Iqgap2
|
UTSW |
13 |
95,772,141 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0360:Iqgap2
|
UTSW |
13 |
95,867,783 (GRCm39) |
splice site |
probably benign |
|
|
R0364:Iqgap2
|
UTSW |
13 |
95,867,783 (GRCm39) |
splice site |
probably benign |
|
|
R0419:Iqgap2
|
UTSW |
13 |
95,826,207 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1229:Iqgap2
|
UTSW |
13 |
95,768,673 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1290:Iqgap2
|
UTSW |
13 |
95,805,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1397:Iqgap2
|
UTSW |
13 |
95,768,673 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1498:Iqgap2
|
UTSW |
13 |
95,783,313 (GRCm39) |
missense |
probably benign |
|
|
R1513:Iqgap2
|
UTSW |
13 |
95,766,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1630:Iqgap2
|
UTSW |
13 |
95,826,293 (GRCm39) |
missense |
probably benign |
|
|
R2088:Iqgap2
|
UTSW |
13 |
96,028,171 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2928:Iqgap2
|
UTSW |
13 |
95,818,744 (GRCm39) |
missense |
probably benign |
|
|
R3026:Iqgap2
|
UTSW |
13 |
95,809,564 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3720:Iqgap2
|
UTSW |
13 |
95,805,036 (GRCm39) |
splice site |
probably null |
|
|
R3846:Iqgap2
|
UTSW |
13 |
95,810,186 (GRCm39) |
splice site |
probably benign |
|
|
R4056:Iqgap2
|
UTSW |
13 |
95,886,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4077:Iqgap2
|
UTSW |
13 |
95,794,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4353:Iqgap2
|
UTSW |
13 |
95,807,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4517:Iqgap2
|
UTSW |
13 |
95,800,569 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4628:Iqgap2
|
UTSW |
13 |
95,899,837 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4686:Iqgap2
|
UTSW |
13 |
95,858,117 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4724:Iqgap2
|
UTSW |
13 |
95,772,005 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4826:Iqgap2
|
UTSW |
13 |
95,899,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4847:Iqgap2
|
UTSW |
13 |
95,810,251 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4967:Iqgap2
|
UTSW |
13 |
95,766,514 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4973:Iqgap2
|
UTSW |
13 |
95,794,305 (GRCm39) |
splice site |
probably null |
|
|
R5010:Iqgap2
|
UTSW |
13 |
95,810,251 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5086:Iqgap2
|
UTSW |
13 |
95,772,088 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5496:Iqgap2
|
UTSW |
13 |
95,766,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5512:Iqgap2
|
UTSW |
13 |
95,811,884 (GRCm39) |
nonsense |
probably null |
|
|
R5629:Iqgap2
|
UTSW |
13 |
95,768,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5824:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5830:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5831:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5832:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5833:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5834:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5852:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5888:Iqgap2
|
UTSW |
13 |
95,772,118 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5889:Iqgap2
|
UTSW |
13 |
95,768,550 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6093:Iqgap2
|
UTSW |
13 |
95,765,471 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6141:Iqgap2
|
UTSW |
13 |
95,858,194 (GRCm39) |
splice site |
probably null |
|
|
R6404:Iqgap2
|
UTSW |
13 |
95,865,985 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6434:Iqgap2
|
UTSW |
13 |
95,819,441 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6648:Iqgap2
|
UTSW |
13 |
95,818,719 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6658:Iqgap2
|
UTSW |
13 |
95,796,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6903:Iqgap2
|
UTSW |
13 |
95,797,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7327:Iqgap2
|
UTSW |
13 |
95,772,163 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7371:Iqgap2
|
UTSW |
13 |
95,836,846 (GRCm39) |
splice site |
probably null |
|
|
R7378:Iqgap2
|
UTSW |
13 |
95,869,398 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7441:Iqgap2
|
UTSW |
13 |
95,764,584 (GRCm39) |
missense |
probably benign |
0.23 |
|
R7575:Iqgap2
|
UTSW |
13 |
95,798,131 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7671:Iqgap2
|
UTSW |
13 |
95,764,627 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7713:Iqgap2
|
UTSW |
13 |
95,867,952 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7806:Iqgap2
|
UTSW |
13 |
95,818,765 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7893:Iqgap2
|
UTSW |
13 |
95,826,217 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8052:Iqgap2
|
UTSW |
13 |
95,794,387 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8121:Iqgap2
|
UTSW |
13 |
95,861,076 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8261:Iqgap2
|
UTSW |
13 |
95,772,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8301:Iqgap2
|
UTSW |
13 |
95,818,659 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8369:Iqgap2
|
UTSW |
13 |
95,798,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8485:Iqgap2
|
UTSW |
13 |
95,796,659 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8709:Iqgap2
|
UTSW |
13 |
95,796,713 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8710:Iqgap2
|
UTSW |
13 |
95,796,756 (GRCm39) |
missense |
probably benign |
0.24 |
|
R8737:Iqgap2
|
UTSW |
13 |
95,802,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8845:Iqgap2
|
UTSW |
13 |
95,794,392 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R8902:Iqgap2
|
UTSW |
13 |
95,818,711 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8957:Iqgap2
|
UTSW |
13 |
95,772,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9153:Iqgap2
|
UTSW |
13 |
95,844,547 (GRCm39) |
missense |
probably benign |
|
|
R9259:Iqgap2
|
UTSW |
13 |
95,766,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9290:Iqgap2
|
UTSW |
13 |
95,886,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9414:Iqgap2
|
UTSW |
13 |
95,783,349 (GRCm39) |
missense |
|
|
|
R9432:Iqgap2
|
UTSW |
13 |
95,774,261 (GRCm39) |
missense |
probably benign |
|
|
R9747:Iqgap2
|
UTSW |
13 |
95,821,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0066:Iqgap2
|
UTSW |
13 |
95,807,891 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Iqgap2
|
UTSW |
13 |
95,867,951 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGGCCTTGAGCTTCAGCAC -3'
(R):5'- TGCTCACTGGTCCTGAGTTGAG -3'
Sequencing Primer
(F):5'- CCAGGAATTAAACTCAGGGCTTTCG -3'
(R):5'- CCTGAGTTGAGGCTCTGTTAG -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation