Incidental Mutation 'R7224:R3hdm2'
| ID |
562045 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
R3hdm2
|
| Ensembl Gene |
ENSMUSG00000025404 |
| Gene Name |
R3H domain containing 2 |
| Synonyms |
1300003K24Rik |
| MMRRC Submission |
045296-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.548)
|
| Stock # |
R7224 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
127216201-127335253 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 127294022 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Glutamine
at position 172
(L172Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000069724
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064793]
[ENSMUST00000077046]
[ENSMUST00000105249]
[ENSMUST00000105250]
[ENSMUST00000105251]
[ENSMUST00000164161]
[ENSMUST00000164831]
[ENSMUST00000165440]
[ENSMUST00000166820]
[ENSMUST00000169888]
[ENSMUST00000170336]
|
| AlphaFold |
Q80TM6 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000064793
AA Change: L172Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000069724
Gene: ENSMUSG00000025404
AA Change: L172Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
low complexity region
|
306 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
398 |
429 |
N/A |
INTRINSIC |
|
low complexity region
|
442 |
457 |
N/A |
INTRINSIC |
|
low complexity region
|
699 |
730 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000077046
AA Change: L172Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000076303
Gene: ENSMUSG00000025404
AA Change: L172Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
Pfam:SUZ
|
250 |
303 |
7.4e-14 |
PFAM |
|
low complexity region
|
338 |
350 |
N/A |
INTRINSIC |
|
low complexity region
|
430 |
461 |
N/A |
INTRINSIC |
|
low complexity region
|
474 |
499 |
N/A |
INTRINSIC |
|
low complexity region
|
744 |
775 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105249
AA Change: L172Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000100884
Gene: ENSMUSG00000025404
AA Change: L172Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
Pfam:SUZ
|
250 |
303 |
5.4e-12 |
PFAM |
|
low complexity region
|
320 |
332 |
N/A |
INTRINSIC |
|
low complexity region
|
412 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
692 |
723 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105250
AA Change: L172Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000100885
Gene: ENSMUSG00000025404
AA Change: L172Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
Pfam:SUZ
|
250 |
303 |
5.6e-12 |
PFAM |
|
low complexity region
|
320 |
332 |
N/A |
INTRINSIC |
|
low complexity region
|
412 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
456 |
481 |
N/A |
INTRINSIC |
|
low complexity region
|
726 |
757 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105251
AA Change: L172Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000100886
Gene: ENSMUSG00000025404
AA Change: L172Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
Pfam:SUZ
|
250 |
303 |
5.6e-12 |
PFAM |
|
low complexity region
|
320 |
332 |
N/A |
INTRINSIC |
|
low complexity region
|
412 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
456 |
481 |
N/A |
INTRINSIC |
|
low complexity region
|
726 |
757 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000164161
|
| SMART Domains |
Protein: ENSMUSP00000126185
Gene: ENSMUSG00000025404
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000164831
AA Change: L172Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000131007
Gene: ENSMUSG00000025404
AA Change: L172Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
low complexity region
|
306 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
398 |
429 |
N/A |
INTRINSIC |
|
low complexity region
|
678 |
709 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000165440
|
| SMART Domains |
Protein: ENSMUSP00000133118
Gene: ENSMUSG00000025404
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:SUZ
|
17 |
64 |
1.4e-13 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000166820
AA Change: L172Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000126608
Gene: ENSMUSG00000025404
AA Change: L172Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
Pfam:SUZ
|
250 |
303 |
5.7e-12 |
PFAM |
|
low complexity region
|
338 |
350 |
N/A |
INTRINSIC |
|
low complexity region
|
430 |
461 |
N/A |
INTRINSIC |
|
low complexity region
|
474 |
499 |
N/A |
INTRINSIC |
|
low complexity region
|
744 |
775 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000169888
|
| SMART Domains |
Protein: ENSMUSP00000126760
Gene: ENSMUSG00000025404
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:SUZ
|
7 |
54 |
4.7e-12 |
PFAM |
|
low complexity region
|
71 |
83 |
N/A |
INTRINSIC |
|
low complexity region
|
163 |
194 |
N/A |
INTRINSIC |
|
low complexity region
|
443 |
474 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000170336
AA Change: L172Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000128659
Gene: ENSMUSG00000025404
AA Change: L172Q
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
30 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
132 |
N/A |
INTRINSIC |
|
R3H
|
152 |
229 |
1.26e-16 |
SMART |
|
low complexity region
|
306 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
398 |
429 |
N/A |
INTRINSIC |
|
low complexity region
|
442 |
467 |
N/A |
INTRINSIC |
|
low complexity region
|
712 |
743 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.4%
|
| Validation Efficiency |
99% (79/80) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadac |
C |
T |
3: 59,943,275 (GRCm39) |
T60M |
probably benign |
Het |
| Actn4 |
C |
T |
7: 28,661,509 (GRCm39) |
A34T |
probably benign |
Het |
| Acvrl1 |
A |
G |
15: 101,041,245 (GRCm39) |
M466V |
probably benign |
Het |
| Adamts7 |
T |
C |
9: 90,067,868 (GRCm39) |
Y453H |
probably damaging |
Het |
| Amfr |
G |
A |
8: 94,711,484 (GRCm39) |
P351S |
probably damaging |
Het |
| Ankrd26 |
G |
A |
6: 118,516,688 (GRCm39) |
T492M |
probably benign |
Het |
| Anxa6 |
A |
G |
11: 54,876,993 (GRCm39) |
F547L |
probably damaging |
Het |
| Ap5m1 |
T |
G |
14: 49,318,384 (GRCm39) |
Y394D |
unknown |
Het |
| Atic |
G |
A |
1: 71,610,014 (GRCm39) |
V342I |
probably benign |
Het |
| Atl1 |
C |
A |
12: 70,002,127 (GRCm39) |
T362N |
probably benign |
Het |
| Atp10a |
A |
T |
7: 58,447,219 (GRCm39) |
M654L |
probably benign |
Het |
| B3gnt5 |
A |
T |
16: 19,588,503 (GRCm39) |
M241L |
probably benign |
Het |
| Bbs7 |
A |
G |
3: 36,659,877 (GRCm39) |
V186A |
possibly damaging |
Het |
| Brme1 |
A |
G |
8: 84,898,842 (GRCm39) |
T577A |
probably benign |
Het |
| C8b |
T |
C |
4: 104,637,795 (GRCm39) |
L89P |
probably damaging |
Het |
| Capn7 |
G |
T |
14: 31,092,678 (GRCm39) |
E742* |
probably null |
Het |
| Ccdc162 |
G |
A |
10: 41,437,187 (GRCm39) |
R1741C |
probably damaging |
Het |
| Cdhr17 |
T |
C |
5: 17,041,592 (GRCm39) |
V615A |
possibly damaging |
Het |
| Chsy3 |
T |
A |
18: 59,542,047 (GRCm39) |
L395H |
probably damaging |
Het |
| Cnot9 |
A |
G |
1: 74,556,388 (GRCm39) |
T62A |
probably benign |
Het |
| Cyfip1 |
AGTGT |
AGT |
7: 55,577,937 (GRCm39) |
|
probably null |
Het |
| Cyp2d12 |
T |
A |
15: 82,441,849 (GRCm39) |
|
probably null |
Het |
| Dnah7a |
A |
G |
1: 53,436,420 (GRCm39) |
V3974A |
probably benign |
Het |
| Dync1h1 |
G |
A |
12: 110,584,196 (GRCm39) |
G533D |
possibly damaging |
Het |
| Eddm13 |
T |
G |
7: 6,271,801 (GRCm39) |
M77R |
probably benign |
Het |
| Elfn1 |
A |
G |
5: 139,958,228 (GRCm39) |
S411G |
probably benign |
Het |
| Enpp3 |
T |
C |
10: 24,652,782 (GRCm39) |
D725G |
possibly damaging |
Het |
| Fmnl1 |
T |
C |
11: 103,073,595 (GRCm39) |
|
probably null |
Het |
| Fndc8 |
T |
C |
11: 82,783,151 (GRCm39) |
M44T |
probably benign |
Het |
| Gcgr |
A |
T |
11: 120,425,538 (GRCm39) |
|
probably benign |
Het |
| Ggt1 |
T |
A |
10: 75,410,110 (GRCm39) |
V14D |
possibly damaging |
Het |
| Gigyf2 |
A |
G |
1: 87,331,447 (GRCm39) |
I198M |
unknown |
Het |
| Gm40460 |
GCAGCAGCTGGACTGGCAGCAGCAGGGCTTACAGCAGCTGGACTGGCAGCAGCAGGGCTTACAGCAGCTGGACTGGCAGCAGCAGGGCTTACAGCAGCTGGACTGGCAGCAG |
GCAGCAGCTGGACTGGCAGCAGCAGGGCTTACAGCAGCTGGACTGGCAGCAGCAGGGCTTACAGCAGCTGGACTGGCAGCAG |
7: 141,794,171 (GRCm39) |
|
probably benign |
Het |
| Gm6034 |
T |
A |
17: 36,367,331 (GRCm39) |
S59T |
unknown |
Het |
| Gm6408 |
G |
A |
5: 146,421,180 (GRCm39) |
V270I |
probably benign |
Het |
| Gpr20 |
A |
T |
15: 73,567,981 (GRCm39) |
I136N |
probably damaging |
Het |
| Ide |
T |
C |
19: 37,268,160 (GRCm39) |
E565G |
|
Het |
| Igsf9 |
T |
C |
1: 172,322,349 (GRCm39) |
S515P |
probably damaging |
Het |
| Kbtbd12 |
G |
A |
6: 88,590,965 (GRCm39) |
R416* |
probably null |
Het |
| Kcnd3 |
A |
T |
3: 105,576,400 (GRCm39) |
I615F |
probably damaging |
Het |
| Kcnk7 |
A |
T |
19: 5,756,805 (GRCm39) |
M265L |
probably benign |
Het |
| Klhdc1 |
G |
A |
12: 69,309,923 (GRCm39) |
S275N |
probably damaging |
Het |
| Ldc1 |
C |
G |
4: 130,112,992 (GRCm39) |
A135P |
probably damaging |
Het |
| Lrba |
A |
C |
3: 86,302,553 (GRCm39) |
N1871T |
probably damaging |
Het |
| Lrrk1 |
A |
G |
7: 65,982,134 (GRCm39) |
V169A |
probably damaging |
Het |
| Magi1 |
A |
G |
6: 93,660,070 (GRCm39) |
I1175T |
probably benign |
Het |
| Man1a2 |
T |
C |
3: 100,489,369 (GRCm39) |
T537A |
possibly damaging |
Het |
| Mrpl17 |
T |
C |
7: 105,459,209 (GRCm39) |
N129S |
probably damaging |
Het |
| Mup5 |
G |
A |
4: 61,750,622 (GRCm39) |
R174C |
probably damaging |
Het |
| Ndufaf1 |
G |
A |
2: 119,488,877 (GRCm39) |
R216C |
probably damaging |
Het |
| Neb |
T |
C |
2: 52,224,671 (GRCm39) |
|
probably null |
Het |
| Olfml3 |
T |
C |
3: 103,643,176 (GRCm39) |
K402E |
probably damaging |
Het |
| Or52m2 |
A |
T |
7: 102,263,974 (GRCm39) |
M74K |
probably damaging |
Het |
| Or5a1 |
T |
C |
19: 12,097,912 (GRCm39) |
T55A |
probably benign |
Het |
| Or8b12b |
G |
A |
9: 37,684,711 (GRCm39) |
G252D |
possibly damaging |
Het |
| Osbpl8 |
C |
T |
10: 111,110,872 (GRCm39) |
P458L |
possibly damaging |
Het |
| Pcdh20 |
T |
C |
14: 88,706,511 (GRCm39) |
E263G |
possibly damaging |
Het |
| Pkd1l1 |
A |
G |
11: 8,895,241 (GRCm39) |
L623P |
|
Het |
| Plxdc1 |
T |
C |
11: 97,823,153 (GRCm39) |
T363A |
possibly damaging |
Het |
| Pole3 |
T |
C |
4: 62,442,287 (GRCm39) |
D111G |
unknown |
Het |
| Rbm33 |
T |
C |
5: 28,599,322 (GRCm39) |
V90A |
|
Het |
| Rcbtb1 |
C |
G |
14: 59,465,828 (GRCm39) |
I390M |
probably damaging |
Het |
| Romo1 |
G |
A |
2: 155,986,295 (GRCm39) |
|
probably benign |
Het |
| Sars1 |
A |
G |
3: 108,335,519 (GRCm39) |
Y410H |
probably damaging |
Het |
| Sesn2 |
T |
C |
4: 132,224,724 (GRCm39) |
T327A |
probably benign |
Het |
| Slc30a5 |
A |
G |
13: 100,945,762 (GRCm39) |
V530A |
probably damaging |
Het |
| Slc30a9 |
G |
A |
5: 67,473,044 (GRCm39) |
E43K |
probably benign |
Het |
| Slc38a2 |
A |
C |
15: 96,589,240 (GRCm39) |
L418W |
probably damaging |
Het |
| Snx14 |
T |
C |
9: 88,276,614 (GRCm39) |
E557G |
possibly damaging |
Het |
| Spata33 |
T |
A |
8: 123,948,737 (GRCm39) |
I123K |
probably damaging |
Het |
| Tdrd3 |
A |
T |
14: 87,714,839 (GRCm39) |
H170L |
probably damaging |
Het |
| Trpm1 |
A |
G |
7: 63,868,854 (GRCm39) |
|
probably null |
Het |
| Tsr3 |
A |
T |
17: 25,461,569 (GRCm39) |
E302D |
probably benign |
Het |
| Ttll11 |
A |
G |
2: 35,792,685 (GRCm39) |
I386T |
probably damaging |
Het |
| Usp2 |
C |
T |
9: 43,987,266 (GRCm39) |
T188M |
possibly damaging |
Het |
| Usp44 |
A |
G |
10: 93,681,855 (GRCm39) |
I102V |
probably benign |
Het |
| Wasf1 |
A |
G |
10: 40,802,546 (GRCm39) |
N67S |
probably benign |
Het |
| Zfp445 |
T |
C |
9: 122,681,208 (GRCm39) |
N911S |
probably benign |
Het |
| Zfp467 |
A |
G |
6: 48,421,903 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in R3hdm2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01397:R3hdm2
|
APN |
10 |
127,294,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02114:R3hdm2
|
APN |
10 |
127,319,978 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02116:R3hdm2
|
APN |
10 |
127,334,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02549:R3hdm2
|
APN |
10 |
127,320,094 (GRCm39) |
splice site |
probably benign |
|
|
IGL02647:R3hdm2
|
APN |
10 |
127,295,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02696:R3hdm2
|
APN |
10 |
127,300,888 (GRCm39) |
splice site |
probably null |
|
|
IGL02732:R3hdm2
|
APN |
10 |
127,319,929 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0131:R3hdm2
|
UTSW |
10 |
127,334,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0131:R3hdm2
|
UTSW |
10 |
127,334,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0132:R3hdm2
|
UTSW |
10 |
127,334,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0157:R3hdm2
|
UTSW |
10 |
127,307,858 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0179:R3hdm2
|
UTSW |
10 |
127,330,975 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0196:R3hdm2
|
UTSW |
10 |
127,320,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0401:R3hdm2
|
UTSW |
10 |
127,294,042 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0505:R3hdm2
|
UTSW |
10 |
127,293,569 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0606:R3hdm2
|
UTSW |
10 |
127,280,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1188:R3hdm2
|
UTSW |
10 |
127,288,624 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1466:R3hdm2
|
UTSW |
10 |
127,312,559 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1466:R3hdm2
|
UTSW |
10 |
127,312,559 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1503:R3hdm2
|
UTSW |
10 |
127,307,695 (GRCm39) |
nonsense |
probably null |
|
|
R1584:R3hdm2
|
UTSW |
10 |
127,312,559 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1652:R3hdm2
|
UTSW |
10 |
127,330,960 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1901:R3hdm2
|
UTSW |
10 |
127,334,337 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R3735:R3hdm2
|
UTSW |
10 |
127,300,879 (GRCm39) |
missense |
probably benign |
|
|
R5261:R3hdm2
|
UTSW |
10 |
127,334,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5329:R3hdm2
|
UTSW |
10 |
127,294,762 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5379:R3hdm2
|
UTSW |
10 |
127,307,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5380:R3hdm2
|
UTSW |
10 |
127,321,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5387:R3hdm2
|
UTSW |
10 |
127,321,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5558:R3hdm2
|
UTSW |
10 |
127,280,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5773:R3hdm2
|
UTSW |
10 |
127,280,172 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R5936:R3hdm2
|
UTSW |
10 |
127,307,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:R3hdm2
|
UTSW |
10 |
127,295,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6160:R3hdm2
|
UTSW |
10 |
127,320,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6191:R3hdm2
|
UTSW |
10 |
127,320,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7058:R3hdm2
|
UTSW |
10 |
127,320,382 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7253:R3hdm2
|
UTSW |
10 |
127,317,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7305:R3hdm2
|
UTSW |
10 |
127,312,547 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7349:R3hdm2
|
UTSW |
10 |
127,328,515 (GRCm39) |
missense |
probably benign |
|
|
R7431:R3hdm2
|
UTSW |
10 |
127,294,016 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7891:R3hdm2
|
UTSW |
10 |
127,334,443 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8477:R3hdm2
|
UTSW |
10 |
127,320,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8503:R3hdm2
|
UTSW |
10 |
127,328,481 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8782:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8783:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8784:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8787:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8789:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8790:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9041:R3hdm2
|
UTSW |
10 |
127,320,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9198:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9200:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9202:R3hdm2
|
UTSW |
10 |
127,293,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9706:R3hdm2
|
UTSW |
10 |
127,334,298 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9760:R3hdm2
|
UTSW |
10 |
127,280,182 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AAGTTCTACAGGAGCAAGCG -3'
(R):5'- GCTTCCACCCATCTGAATGTTG -3'
Sequencing Primer
(F):5'- TTCTACAGGAGCAAGCGAGTGAC -3'
(R):5'- CATTACAGATGGTTGTGAGCCACC -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation