Mutagenetix > Incidental Mutation

Incidental Mutation 'R7231:Dnah9'

562489

Institutional Source

Beutler Lab

Gene Symbol

Dnah9

Ensembl Gene

ENSMUSG00000056752

Gene Name

dynein, axonemal, heavy chain 9

Synonyms

D11Ertd686e, Dnahc9

MMRRC Submission

045342-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.294) question?

Stock #

R7231 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

65831282-66168551 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 65965647 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 2896 (D2896G)

Ref Sequence

ENSEMBL: ENSMUSP00000079494 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000080665]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000080665
AA Change: D2896G

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000079494
Gene: ENSMUSG00000056752
AA Change: D2896G

Domain	Start	End	E-Value	Type
Pfam:DHC_N1	209	787	3.6e-164	PFAM
coiled coil region	788	820	N/A	INTRINSIC
low complexity region	1228	1240	N/A	INTRINSIC
Pfam:DHC_N2	1290	1699	1.4e-134	PFAM
AAA	1863	1999	4.9e-1	SMART
AAA	2141	2341	1.99e0	SMART
AAA	2468	2614	6.75e-1	SMART
Pfam:AAA_8	2786	3053	1.1e-165	PFAM
Pfam:MT	3065	3408	7.2e-208	PFAM
Pfam:AAA_9	3430	3652	3.2e-87	PFAM
Pfam:Dynein_heavy	3786	4482	1e-241	PFAM

Predicted Effect

SMART Domains

Protein: ENSMUSP00000116499
Gene: ENSMUSG00000056752
AA Change: D445G

Domain	Start	End	E-Value	Type
Pfam:AAA_7	1	258	3e-155	PFAM
Pfam:AAA_8	336	603	3.9e-166	PFAM
Pfam:MT	615	958	2.3e-208	PFAM
Pfam:AAA_9	980	1202	1.1e-87	PFAM
Pfam:Dynein_heavy	1336	1514	2.4e-52	PFAM
Pfam:Dynein_heavy	1508	1956	8.6e-155	PFAM

Meta Mutation Damage Score

0.2271

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.3%

Validation Efficiency

98% (78/80)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes the heavy chain subunit of axonemal dynein, a large multi-subunit molecular motor. Axonemal dynein attaches to microtubules and hydrolyzes ATP to mediate the movement of cilia and flagella. The gene expresses at least two transcript variants; additional variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 82 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca13	A	T	11: 9,294,175 (GRCm38)	T2013S	probably benign	Het
Ablim3	A	G	18: 61,805,064 (GRCm38)		probably null	Het
Acvrl1	T	A	15: 101,136,223 (GRCm38)	C206*	probably null	Het
Adamts15	C	A	9: 30,906,158 (GRCm38)	R541S	probably damaging	Het
Add3	A	G	19: 53,233,146 (GRCm38)	I230V	probably benign	Het
Ankrd27	A	G	7: 35,628,446 (GRCm38)	D742G	possibly damaging	Het
Asxl3	A	G	18: 22,517,540 (GRCm38)	E862G	probably damaging	Het
Asxl3	A	T	18: 22,411,499 (GRCm38)		probably null	Het
Atp2b2	G	A	6: 113,765,732 (GRCm38)	T798M	possibly damaging	Het
Car12	T	C	9: 66,752,317 (GRCm38)	I208T	probably damaging	Het
Cgn	T	A	3: 94,773,192 (GRCm38)	Q600L	probably damaging	Het
Cgnl1	C	T	9: 71,632,645 (GRCm38)	A1106T	probably benign	Het
Cmtr2	T	C	8: 110,222,546 (GRCm38)	V496A	probably benign	Het
Cplx4	C	A	18: 65,957,052 (GRCm38)	D99Y	probably damaging	Het
Cyfip2	T	C	11: 46,224,136 (GRCm38)	T915A	probably benign	Het
Cyp4a32	T	C	4: 115,609,697 (GRCm38)	L193P	probably damaging	Het
Dennd5b	C	T	6: 149,044,604 (GRCm38)	R503Q	probably damaging	Het
Depdc5	C	A	5: 32,901,865 (GRCm38)	Q303K	possibly damaging	Het
Dlx1	T	A	2: 71,532,496 (GRCm38)	M249K	possibly damaging	Het
Dnah10	A	T	5: 124,813,828 (GRCm38)	E3218V	probably benign	Het
Dtx4	C	A	19: 12,469,658 (GRCm38)	G557*	probably null	Het
Eps8l2	A	G	7: 141,360,392 (GRCm38)	N512D	probably damaging	Het
Fam20a	T	C	11: 109,721,375 (GRCm38)	D114G	possibly damaging	Het
Fbln1	T	C	15: 85,206,152 (GRCm38)	S7P	unknown	Het
Fli1	T	C	9: 32,424,188 (GRCm38)	E316G	probably damaging	Het
Fmn2	CCCTCCTCTCCCTGGAATGGGAATACCTCCCCCACCTCCTCTCCCTGGAATGGGAATACCTCCCCCACCTCCTCTCCCTGGAATGGGAATATCTCCCCTACCTCCTCTCCCTGGAATGGGAATACCTCC	CCCTCCTCTCCCTGGAATGGGAATACCTCCCCCACCTCCTCTCCCTGGAATGGGAATATCTCCCCTACCTCCTCTCCCTGGAATGGGAATACCTCC	1: 174,609,203 (GRCm38)		probably benign	Het
Haus8	G	A	8: 71,253,137 (GRCm38)	T302I	probably benign	Het
Hmcn1	T	C	1: 150,638,876 (GRCm38)	I3582V	probably benign	Het
Hnrnpul1	G	A	7: 25,748,417 (GRCm38)	Q161*	probably null	Het
Hsf4	C	T	8: 105,272,147 (GRCm38)	A223V	probably damaging	Het
Ighg2c	A	G	12: 113,288,016 (GRCm38)	W164R		Het
Isl1	A	G	13: 116,303,290 (GRCm38)	V174A	probably benign	Het
Itih4	A	T	14: 30,896,614 (GRCm38)	I661F	probably benign	Het
Klhl14	A	T	18: 21,652,136 (GRCm38)	L78Q	probably damaging	Het
L3mbtl3	T	A	10: 26,339,282 (GRCm38)	I177F	unknown	Het
Lingo3	T	A	10: 80,835,104 (GRCm38)	T331S	possibly damaging	Het
Lrrc36	T	C	8: 105,461,057 (GRCm38)	V535A	possibly damaging	Het
Mapk8ip2	T	G	15: 89,458,076 (GRCm38)	S497A	probably benign	Het
Mbip	A	G	12: 56,337,762 (GRCm38)		probably null	Het
Nelfa	C	T	5: 33,898,825 (GRCm38)	G498D	probably damaging	Het
Nlrc5	T	A	8: 94,521,805 (GRCm38)		probably null	Het
Olfr1312	A	T	2: 112,042,366 (GRCm38)	V222D	probably damaging	Het
Olfr679	T	C	7: 105,085,787 (GRCm38)	S24P	possibly damaging	Het
Olfr701	A	T	7: 106,818,443 (GRCm38)	Y120F	probably damaging	Het
Olfr863-ps1	T	A	9: 19,941,559 (GRCm38)	T294S	unknown	Het
Pde2a	A	G	7: 101,505,953 (GRCm38)	Y567C	probably damaging	Het
Pdia4	A	T	6: 47,800,957 (GRCm38)	F367Y	probably benign	Het
Pkdrej	C	A	15: 85,816,188 (GRCm38)	C1849F	possibly damaging	Het
Plekhj1	T	G	10: 80,797,658 (GRCm38)	T52P	probably damaging	Het
Ppp2r5d	A	T	17: 46,684,060 (GRCm38)	Y572N	probably benign	Het
Prkcq	T	A	2: 11,290,451 (GRCm38)	Y570*	probably null	Het
Ptpn3	T	A	4: 57,245,062 (GRCm38)	D226V	probably damaging	Het
Rab1b	A	G	19: 5,105,201 (GRCm38)	S22P	probably damaging	Het
Ralgapa1	A	G	12: 55,604,191 (GRCm38)	S2060P	probably damaging	Het
Rnf148	G	T	6: 23,654,891 (GRCm38)	S35R	probably benign	Het
Runx2	G	A	17: 44,814,192 (GRCm38)	P80L	probably damaging	Het
Samd15	T	A	12: 87,201,044 (GRCm38)	S168T	possibly damaging	Het
Slc26a4	T	A	12: 31,547,946 (GRCm38)	N167I	probably damaging	Het
Slc39a1	C	A	3: 90,251,790 (GRCm38)	H141Q	probably benign	Het
Slc9a3r2	C	T	17: 24,650,104 (GRCm38)	R16H	probably damaging	Het
Snx21	T	C	2: 164,786,201 (GRCm38)	S46P	probably benign	Het
Strip2	A	G	6: 29,944,487 (GRCm38)	S657G	probably damaging	Het
Stxbp3	G	A	3: 108,800,809 (GRCm38)	P392L	probably damaging	Het
Suclg1	G	A	6: 73,263,971 (GRCm38)	R161H	probably benign	Het
Tas1r3	T	C	4: 155,862,826 (GRCm38)	Y134C	probably damaging	Het
Tgif1	T	A	17: 70,846,173 (GRCm38)	Q114L	probably damaging	Het
Tll2	A	G	19: 41,086,234 (GRCm38)	F964L	probably benign	Het
Tmem181a	T	C	17: 6,297,920 (GRCm38)	S247P	possibly damaging	Het
Trav23	A	T	14: 53,977,568 (GRCm38)	R79S	probably damaging	Het
Trf	C	A	9: 103,225,148 (GRCm38)	C177F	probably damaging	Het
Triml1	T	C	8: 43,136,371 (GRCm38)	Y260C	probably benign	Het
Tulp4	T	C	17: 6,236,235 (GRCm38)	F1513L	probably benign	Het
Umodl1	G	A	17: 30,986,116 (GRCm38)	V562I	probably damaging	Het
Ush2a	A	G	1: 188,759,763 (GRCm38)	K3083R	possibly damaging	Het
Vmn1r74	A	T	7: 11,846,961 (GRCm38)	I63F	probably benign	Het
Vmn2r38	C	T	7: 9,097,638 (GRCm38)	C43Y	possibly damaging	Het
Vmn2r50	A	T	7: 10,053,083 (GRCm38)	N32K	probably benign	Het
Vps13d	A	G	4: 145,057,462 (GRCm38)	V3914A		Het
Vwa5b2	A	G	16: 20,604,128 (GRCm38)	T984A	probably benign	Het
Zc3h3	C	T	15: 75,840,382 (GRCm38)	V77M	probably damaging	Het
Zfp397	A	T	18: 23,960,358 (GRCm38)	H300L	probably damaging	Het
Zfp950	G	A	19: 61,119,212 (GRCm38)	R478C	probably benign	Het

Other mutations in Dnah9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00696:Dnah9	APN	11	65,841,238 (GRCm38)	splice site	probably benign
IGL00805:Dnah9	APN	11	65,881,695 (GRCm38)	missense	probably benign	0.00
IGL00826:Dnah9	APN	11	65,989,942 (GRCm38)	missense	probably damaging	1.00
IGL01108:Dnah9	APN	11	65,849,980 (GRCm38)	missense	possibly damaging	0.93
IGL01152:Dnah9	APN	11	66,072,056 (GRCm38)	missense	probably damaging	1.00
IGL01353:Dnah9	APN	11	66,080,571 (GRCm38)	missense	probably damaging	1.00
IGL01364:Dnah9	APN	11	66,155,459 (GRCm38)	missense	probably damaging	1.00
IGL01479:Dnah9	APN	11	65,955,717 (GRCm38)	missense	probably benign	0.14
IGL01537:Dnah9	APN	11	65,947,680 (GRCm38)	missense	probably benign
IGL01565:Dnah9	APN	11	66,033,829 (GRCm38)	missense	possibly damaging	0.95
IGL01597:Dnah9	APN	11	66,118,830 (GRCm38)	missense	probably damaging	1.00
IGL01619:Dnah9	APN	11	65,831,615 (GRCm38)	nonsense	probably null
IGL01625:Dnah9	APN	11	66,044,645 (GRCm38)	missense	probably damaging	1.00
IGL01803:Dnah9	APN	11	66,118,829 (GRCm38)	missense	probably damaging	1.00
IGL01819:Dnah9	APN	11	66,108,126 (GRCm38)	missense	probably benign	0.33
IGL01896:Dnah9	APN	11	66,130,666 (GRCm38)	missense	possibly damaging	0.89
IGL01922:Dnah9	APN	11	66,075,034 (GRCm38)	splice site	probably benign
IGL01923:Dnah9	APN	11	66,125,235 (GRCm38)	splice site	probably benign
IGL02059:Dnah9	APN	11	66,072,958 (GRCm38)	missense	probably damaging	1.00
IGL02068:Dnah9	APN	11	66,061,045 (GRCm38)	missense	probably damaging	1.00
IGL02135:Dnah9	APN	11	66,117,492 (GRCm38)	missense	possibly damaging	0.63
IGL02146:Dnah9	APN	11	65,927,700 (GRCm38)	missense	probably damaging	1.00
IGL02264:Dnah9	APN	11	66,080,488 (GRCm38)	splice site	probably benign
IGL02325:Dnah9	APN	11	65,834,217 (GRCm38)	missense	probably damaging	1.00
IGL02426:Dnah9	APN	11	66,125,153 (GRCm38)	missense	probably benign
IGL02440:Dnah9	APN	11	65,955,246 (GRCm38)	missense	probably damaging	1.00
IGL02471:Dnah9	APN	11	65,947,618 (GRCm38)	nonsense	probably null
IGL02496:Dnah9	APN	11	66,029,363 (GRCm38)	missense	probably damaging	1.00
IGL02672:Dnah9	APN	11	65,927,601 (GRCm38)	missense	probably benign	0.02
IGL02718:Dnah9	APN	11	65,886,640 (GRCm38)	missense	probably damaging	0.99
IGL02832:Dnah9	APN	11	66,040,346 (GRCm38)	missense	probably damaging	1.00
IGL02851:Dnah9	APN	11	66,037,744 (GRCm38)	splice site	probably benign
IGL02859:Dnah9	APN	11	65,881,619 (GRCm38)	splice site	probably benign
IGL02864:Dnah9	APN	11	66,061,003 (GRCm38)	missense	probably damaging	1.00
IGL02954:Dnah9	APN	11	66,118,967 (GRCm38)	missense	probably damaging	1.00
IGL02987:Dnah9	APN	11	65,841,273 (GRCm38)	missense	probably benign	0.23
IGL02987:Dnah9	APN	11	65,855,272 (GRCm38)	missense	probably damaging	0.98
IGL03160:Dnah9	APN	11	66,108,054 (GRCm38)	missense	probably damaging	0.98
IGL03171:Dnah9	APN	11	65,981,241 (GRCm38)	missense	probably benign	0.13
IGL03180:Dnah9	APN	11	65,886,639 (GRCm38)	missense	probably damaging	0.99
IGL03388:Dnah9	APN	11	65,947,542 (GRCm38)	missense	probably damaging	1.00
anarchy	UTSW	11	65,955,248 (GRCm38)	missense	probably damaging	0.99
sacco	UTSW	11	66,168,079 (GRCm38)	missense	possibly damaging	0.82
Tweed	UTSW	11	66,072,072 (GRCm38)	missense	probably damaging	0.99
vanzetti	UTSW	11	65,855,372 (GRCm38)	nonsense	probably null
IGL02837:Dnah9	UTSW	11	65,874,196 (GRCm38)	missense	probably damaging	1.00
PIT4280001:Dnah9	UTSW	11	66,005,013 (GRCm38)	missense	probably benign	0.44
R0021:Dnah9	UTSW	11	65,969,979 (GRCm38)	missense	probably benign	0.36
R0021:Dnah9	UTSW	11	65,969,979 (GRCm38)	missense	probably benign	0.36
R0025:Dnah9	UTSW	11	65,969,955 (GRCm38)	splice site	probably benign
R0025:Dnah9	UTSW	11	65,969,955 (GRCm38)	splice site	probably benign
R0070:Dnah9	UTSW	11	66,160,040 (GRCm38)	missense	probably benign	0.10
R0164:Dnah9	UTSW	11	65,918,804 (GRCm38)	nonsense	probably null
R0164:Dnah9	UTSW	11	65,918,804 (GRCm38)	nonsense	probably null
R0180:Dnah9	UTSW	11	66,147,290 (GRCm38)	missense	probably damaging	1.00
R0195:Dnah9	UTSW	11	65,895,905 (GRCm38)	missense	probably benign	0.30
R0230:Dnah9	UTSW	11	65,855,315 (GRCm38)	missense	probably damaging	1.00
R0243:Dnah9	UTSW	11	65,911,852 (GRCm38)	missense	possibly damaging	0.91
R0279:Dnah9	UTSW	11	65,911,789 (GRCm38)	critical splice donor site	probably null
R0288:Dnah9	UTSW	11	66,025,134 (GRCm38)	critical splice donor site	probably null
R0309:Dnah9	UTSW	11	66,026,972 (GRCm38)	splice site	probably benign
R0356:Dnah9	UTSW	11	66,130,562 (GRCm38)	critical splice donor site	probably null
R0403:Dnah9	UTSW	11	66,084,789 (GRCm38)	missense	possibly damaging	0.90
R0413:Dnah9	UTSW	11	66,108,135 (GRCm38)	missense	probably damaging	1.00
R0448:Dnah9	UTSW	11	65,918,713 (GRCm38)	splice site	probably benign
R0496:Dnah9	UTSW	11	66,075,135 (GRCm38)	missense	probably null	1.00
R0557:Dnah9	UTSW	11	66,084,666 (GRCm38)	missense	probably damaging	1.00
R0584:Dnah9	UTSW	11	65,990,489 (GRCm38)	missense	probably damaging	1.00
R0598:Dnah9	UTSW	11	66,118,877 (GRCm38)	missense	probably benign	0.02
R0599:Dnah9	UTSW	11	65,965,689 (GRCm38)	missense	probably damaging	1.00
R0606:Dnah9	UTSW	11	65,841,333 (GRCm38)	missense	probably damaging	1.00
R0666:Dnah9	UTSW	11	66,085,458 (GRCm38)	missense	probably benign	0.01
R0715:Dnah9	UTSW	11	66,081,248 (GRCm38)	splice site	probably benign
R0726:Dnah9	UTSW	11	65,965,681 (GRCm38)	missense	probably damaging	1.00
R0737:Dnah9	UTSW	11	66,107,898 (GRCm38)	missense	probably damaging	1.00
R0763:Dnah9	UTSW	11	66,155,530 (GRCm38)	missense	probably benign	0.30
R0792:Dnah9	UTSW	11	65,896,001 (GRCm38)	missense	possibly damaging	0.84
R0829:Dnah9	UTSW	11	66,005,176 (GRCm38)	missense	probably benign	0.00
R0973:Dnah9	UTSW	11	66,005,837 (GRCm38)	splice site	probably null
R0974:Dnah9	UTSW	11	66,005,837 (GRCm38)	splice site	probably null
R1055:Dnah9	UTSW	11	66,160,011 (GRCm38)	missense	probably damaging	1.00
R1081:Dnah9	UTSW	11	66,084,877 (GRCm38)	missense	probably damaging	0.99
R1184:Dnah9	UTSW	11	66,084,612 (GRCm38)	critical splice donor site	probably null
R1225:Dnah9	UTSW	11	65,871,060 (GRCm38)	missense	possibly damaging	0.94
R1304:Dnah9	UTSW	11	65,927,588 (GRCm38)	missense	probably damaging	0.98
R1417:Dnah9	UTSW	11	65,955,747 (GRCm38)	missense	probably damaging	0.96
R1439:Dnah9	UTSW	11	65,874,132 (GRCm38)	missense	probably benign	0.22
R1447:Dnah9	UTSW	11	66,108,482 (GRCm38)	missense	possibly damaging	0.65
R1450:Dnah9	UTSW	11	65,927,786 (GRCm38)	missense	probably damaging	1.00
R1470:Dnah9	UTSW	11	65,927,822 (GRCm38)	missense	probably benign	0.11
R1470:Dnah9	UTSW	11	65,927,822 (GRCm38)	missense	probably benign	0.11
R1486:Dnah9	UTSW	11	65,834,272 (GRCm38)	missense	probably damaging	1.00
R1519:Dnah9	UTSW	11	65,881,761 (GRCm38)	missense	probably damaging	0.96
R1570:Dnah9	UTSW	11	66,112,330 (GRCm38)	missense	probably benign
R1617:Dnah9	UTSW	11	65,895,921 (GRCm38)	missense	probably damaging	1.00
R1623:Dnah9	UTSW	11	66,037,637 (GRCm38)	missense	probably damaging	1.00
R1626:Dnah9	UTSW	11	66,085,267 (GRCm38)	missense	probably benign	0.05
R1671:Dnah9	UTSW	11	65,927,963 (GRCm38)	missense	probably damaging	0.99
R1694:Dnah9	UTSW	11	65,954,824 (GRCm38)	nonsense	probably null
R1701:Dnah9	UTSW	11	65,911,924 (GRCm38)	missense	probably damaging	1.00
R1702:Dnah9	UTSW	11	66,085,195 (GRCm38)	missense	possibly damaging	0.72
R1708:Dnah9	UTSW	11	65,915,154 (GRCm38)	missense	probably benign	0.11
R1718:Dnah9	UTSW	11	66,168,079 (GRCm38)	missense	possibly damaging	0.82
R1729:Dnah9	UTSW	11	66,085,020 (GRCm38)	missense	possibly damaging	0.51
R1760:Dnah9	UTSW	11	65,981,222 (GRCm38)	missense	probably benign	0.31
R1784:Dnah9	UTSW	11	66,085,020 (GRCm38)	missense	possibly damaging	0.51
R1793:Dnah9	UTSW	11	66,119,594 (GRCm38)	critical splice donor site	probably null
R1801:Dnah9	UTSW	11	65,955,297 (GRCm38)	missense	probably damaging	0.99
R1827:Dnah9	UTSW	11	65,850,061 (GRCm38)	missense	probably damaging	0.97
R1836:Dnah9	UTSW	11	66,118,841 (GRCm38)	missense	probably benign	0.10
R1840:Dnah9	UTSW	11	65,834,198 (GRCm38)	nonsense	probably null
R1847:Dnah9	UTSW	11	65,834,386 (GRCm38)	missense	probably damaging	1.00
R1872:Dnah9	UTSW	11	66,037,490 (GRCm38)	missense	probably benign	0.16
R1929:Dnah9	UTSW	11	65,976,398 (GRCm38)	missense	probably benign	0.05
R1969:Dnah9	UTSW	11	65,848,371 (GRCm38)	missense	probably damaging	1.00
R1971:Dnah9	UTSW	11	65,848,371 (GRCm38)	missense	probably damaging	1.00
R2027:Dnah9	UTSW	11	65,955,338 (GRCm38)	missense	probably benign	0.11
R2049:Dnah9	UTSW	11	66,044,683 (GRCm38)	missense	probably damaging	1.00
R2064:Dnah9	UTSW	11	66,145,435 (GRCm38)	missense	probably benign	0.31
R2104:Dnah9	UTSW	11	66,061,124 (GRCm38)	missense	probably damaging	1.00
R2109:Dnah9	UTSW	11	66,037,585 (GRCm38)	missense	probably damaging	1.00
R2160:Dnah9	UTSW	11	66,117,483 (GRCm38)	missense	probably damaging	1.00
R2172:Dnah9	UTSW	11	66,072,779 (GRCm38)	missense	probably damaging	1.00
R2198:Dnah9	UTSW	11	65,859,499 (GRCm38)	missense	possibly damaging	0.50
R2271:Dnah9	UTSW	11	66,112,362 (GRCm38)	missense	probably benign	0.37
R2272:Dnah9	UTSW	11	66,112,362 (GRCm38)	missense	probably benign	0.37
R2396:Dnah9	UTSW	11	66,085,158 (GRCm38)	missense	probably benign	0.01
R2398:Dnah9	UTSW	11	65,915,203 (GRCm38)	missense	probably damaging	1.00
R2418:Dnah9	UTSW	11	66,095,415 (GRCm38)	nonsense	probably null
R2419:Dnah9	UTSW	11	66,095,415 (GRCm38)	nonsense	probably null
R2510:Dnah9	UTSW	11	66,005,169 (GRCm38)	missense	probably damaging	1.00
R2680:Dnah9	UTSW	11	66,033,925 (GRCm38)	missense	probably benign	0.00
R2875:Dnah9	UTSW	11	66,168,461 (GRCm38)	missense	possibly damaging	0.89
R2979:Dnah9	UTSW	11	66,117,588 (GRCm38)	missense	possibly damaging	0.89
R3236:Dnah9	UTSW	11	65,954,989 (GRCm38)	missense	probably benign	0.11
R3237:Dnah9	UTSW	11	65,954,989 (GRCm38)	missense	probably benign	0.11
R3433:Dnah9	UTSW	11	66,075,112 (GRCm38)	missense	possibly damaging	0.85
R3737:Dnah9	UTSW	11	66,156,908 (GRCm38)	nonsense	probably null
R3820:Dnah9	UTSW	11	65,851,003 (GRCm38)	critical splice donor site	probably null
R3821:Dnah9	UTSW	11	65,851,003 (GRCm38)	critical splice donor site	probably null
R3822:Dnah9	UTSW	11	65,851,003 (GRCm38)	critical splice donor site	probably null
R3861:Dnah9	UTSW	11	66,052,994 (GRCm38)	splice site	probably benign
R3918:Dnah9	UTSW	11	65,870,974 (GRCm38)	missense	possibly damaging	0.54
R4011:Dnah9	UTSW	11	65,834,464 (GRCm38)	missense	probably damaging	0.98
R4044:Dnah9	UTSW	11	66,133,635 (GRCm38)	missense	probably benign	0.03
R4072:Dnah9	UTSW	11	66,084,904 (GRCm38)	missense	probably benign	0.00
R4076:Dnah9	UTSW	11	66,084,904 (GRCm38)	missense	probably benign	0.00
R4097:Dnah9	UTSW	11	65,990,459 (GRCm38)	missense	probably damaging	1.00
R4409:Dnah9	UTSW	11	66,085,477 (GRCm38)	missense	possibly damaging	0.51
R4410:Dnah9	UTSW	11	66,085,477 (GRCm38)	missense	possibly damaging	0.51
R4417:Dnah9	UTSW	11	65,981,214 (GRCm38)	missense	possibly damaging	0.75
R4420:Dnah9	UTSW	11	66,118,749 (GRCm38)	missense	probably benign	0.00
R4434:Dnah9	UTSW	11	66,108,075 (GRCm38)	missense	possibly damaging	0.67
R4451:Dnah9	UTSW	11	65,881,641 (GRCm38)	missense	probably benign	0.07
R4452:Dnah9	UTSW	11	66,027,082 (GRCm38)	missense	probably damaging	0.96
R4454:Dnah9	UTSW	11	66,147,389 (GRCm38)	missense	probably damaging	0.96
R4551:Dnah9	UTSW	11	65,841,366 (GRCm38)	missense	probably damaging	1.00
R4552:Dnah9	UTSW	11	65,841,366 (GRCm38)	missense	probably damaging	1.00
R4590:Dnah9	UTSW	11	66,040,392 (GRCm38)	missense	probably damaging	1.00
R4595:Dnah9	UTSW	11	66,168,152 (GRCm38)	missense	probably benign
R4655:Dnah9	UTSW	11	65,955,732 (GRCm38)	missense	probably benign	0.00
R4667:Dnah9	UTSW	11	66,155,531 (GRCm38)	missense	probably benign
R4718:Dnah9	UTSW	11	66,085,473 (GRCm38)	missense	probably benign
R4720:Dnah9	UTSW	11	66,076,358 (GRCm38)	missense	probably damaging	1.00
R4734:Dnah9	UTSW	11	65,834,115 (GRCm38)	missense	probably damaging	1.00
R4749:Dnah9	UTSW	11	65,834,115 (GRCm38)	missense	probably damaging	1.00
R4765:Dnah9	UTSW	11	65,927,726 (GRCm38)	missense	probably damaging	1.00
R4905:Dnah9	UTSW	11	65,874,124 (GRCm38)	nonsense	probably null
R4963:Dnah9	UTSW	11	66,084,611 (GRCm38)	splice site	probably null
R5074:Dnah9	UTSW	11	65,850,040 (GRCm38)	missense	probably damaging	1.00
R5230:Dnah9	UTSW	11	66,084,666 (GRCm38)	missense	probably damaging	0.99
R5262:Dnah9	UTSW	11	66,112,333 (GRCm38)	missense	probably benign	0.34
R5364:Dnah9	UTSW	11	65,881,696 (GRCm38)	missense	possibly damaging	0.93
R5370:Dnah9	UTSW	11	66,029,354 (GRCm38)	missense	probably damaging	1.00
R5386:Dnah9	UTSW	11	66,029,356 (GRCm38)	missense	probably damaging	1.00
R5389:Dnah9	UTSW	11	66,095,314 (GRCm38)	nonsense	probably null
R5541:Dnah9	UTSW	11	66,145,336 (GRCm38)	missense	probably damaging	1.00
R5560:Dnah9	UTSW	11	65,881,740 (GRCm38)	missense	probably benign	0.00
R5576:Dnah9	UTSW	11	65,834,096 (GRCm38)	splice site	probably null
R5648:Dnah9	UTSW	11	65,927,755 (GRCm38)	missense	probably benign	0.00
R5653:Dnah9	UTSW	11	65,849,980 (GRCm38)	missense	probably damaging	0.99
R5713:Dnah9	UTSW	11	66,025,223 (GRCm38)	missense	possibly damaging	0.92
R5763:Dnah9	UTSW	11	65,955,239 (GRCm38)	missense	probably damaging	1.00
R5825:Dnah9	UTSW	11	66,126,601 (GRCm38)	missense	probably benign	0.01
R5831:Dnah9	UTSW	11	66,108,121 (GRCm38)	missense	probably benign	0.00
R5847:Dnah9	UTSW	11	66,095,240 (GRCm38)	frame shift	probably null
R5870:Dnah9	UTSW	11	66,085,210 (GRCm38)	missense	probably benign	0.01
R5902:Dnah9	UTSW	11	66,025,187 (GRCm38)	missense	probably benign	0.08
R5918:Dnah9	UTSW	11	65,834,199 (GRCm38)	missense	probably damaging	1.00
R5979:Dnah9	UTSW	11	65,834,481 (GRCm38)	missense	probably damaging	1.00
R6065:Dnah9	UTSW	11	66,145,397 (GRCm38)	missense	possibly damaging	0.65
R6065:Dnah9	UTSW	11	65,855,338 (GRCm38)	missense	probably benign	0.05
R6086:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
R6086:Dnah9	UTSW	11	65,989,915 (GRCm38)	missense	probably damaging	0.99
R6102:Dnah9	UTSW	11	65,990,516 (GRCm38)	missense	probably damaging	0.97
R6120:Dnah9	UTSW	11	66,147,399 (GRCm38)	missense	probably benign
R6154:Dnah9	UTSW	11	65,855,338 (GRCm38)	missense	probably benign	0.00
R6262:Dnah9	UTSW	11	65,881,805 (GRCm38)	splice site	probably null
R6265:Dnah9	UTSW	11	66,168,094 (GRCm38)	missense	probably benign	0.04
R6290:Dnah9	UTSW	11	65,841,375 (GRCm38)	missense	probably damaging	1.00
R6345:Dnah9	UTSW	11	66,037,693 (GRCm38)	missense	probably damaging	0.97
R6357:Dnah9	UTSW	11	65,874,196 (GRCm38)	missense	probably damaging	1.00
R6534:Dnah9	UTSW	11	65,955,248 (GRCm38)	missense	probably damaging	0.99
R6574:Dnah9	UTSW	11	66,168,281 (GRCm38)	missense	probably benign	0.37
R6582:Dnah9	UTSW	11	66,061,097 (GRCm38)	missense	probably damaging	1.00
R6700:Dnah9	UTSW	11	65,955,366 (GRCm38)	missense	probably damaging	1.00
R6800:Dnah9	UTSW	11	66,072,739 (GRCm38)	critical splice donor site	probably null
R6812:Dnah9	UTSW	11	65,981,329 (GRCm38)	missense	probably damaging	0.99
R6931:Dnah9	UTSW	11	66,117,626 (GRCm38)	missense	possibly damaging	0.63
R6944:Dnah9	UTSW	11	66,085,149 (GRCm38)	missense	possibly damaging	0.91
R6958:Dnah9	UTSW	11	66,076,341 (GRCm38)	missense	probably damaging	1.00
R6977:Dnah9	UTSW	11	66,107,909 (GRCm38)	missense	probably benign	0.37
R7021:Dnah9	UTSW	11	65,981,231 (GRCm38)	missense	probably benign
R7161:Dnah9	UTSW	11	65,855,372 (GRCm38)	nonsense	probably null
R7175:Dnah9	UTSW	11	66,133,637 (GRCm38)	missense	probably benign	0.03
R7199:Dnah9	UTSW	11	66,118,944 (GRCm38)	missense	probably benign	0.04
R7284:Dnah9	UTSW	11	65,990,476 (GRCm38)	missense	probably damaging	0.99
R7314:Dnah9	UTSW	11	65,989,851 (GRCm38)	missense	probably benign	0.00
R7350:Dnah9	UTSW	11	66,080,578 (GRCm38)	missense	probably damaging	1.00
R7420:Dnah9	UTSW	11	66,117,407 (GRCm38)	critical splice donor site	probably null
R7427:Dnah9	UTSW	11	65,955,219 (GRCm38)	missense	probably benign
R7477:Dnah9	UTSW	11	65,992,731 (GRCm38)	missense	probably damaging	0.98
R7515:Dnah9	UTSW	11	65,841,414 (GRCm38)	missense	probably benign	0.01
R7521:Dnah9	UTSW	11	65,989,837 (GRCm38)	missense	probably damaging	0.98
R7573:Dnah9	UTSW	11	66,125,215 (GRCm38)	missense	probably benign	0.43
R7659:Dnah9	UTSW	11	65,989,780 (GRCm38)	missense	probably damaging	0.99
R7707:Dnah9	UTSW	11	66,118,958 (GRCm38)	missense	probably damaging	1.00
R7749:Dnah9	UTSW	11	65,911,830 (GRCm38)	missense	probably damaging	1.00
R7792:Dnah9	UTSW	11	65,850,013 (GRCm38)	missense	probably damaging	1.00
R7808:Dnah9	UTSW	11	66,005,805 (GRCm38)	nonsense	probably null
R7814:Dnah9	UTSW	11	66,005,660 (GRCm38)	missense	probably damaging	1.00
R7818:Dnah9	UTSW	11	66,025,211 (GRCm38)	missense	possibly damaging	0.64
R7890:Dnah9	UTSW	11	66,072,072 (GRCm38)	missense	probably damaging	0.99
R7976:Dnah9	UTSW	11	65,841,401 (GRCm38)	missense	possibly damaging	0.91
R8121:Dnah9	UTSW	11	66,017,375 (GRCm38)	missense	probably benign	0.02
R8232:Dnah9	UTSW	11	65,855,323 (GRCm38)	missense	possibly damaging	0.91
R8311:Dnah9	UTSW	11	65,989,818 (GRCm38)	missense	probably benign	0.00
R8326:Dnah9	UTSW	11	66,117,626 (GRCm38)	missense	probably benign	0.01
R8338:Dnah9	UTSW	11	65,841,241 (GRCm38)	critical splice donor site	probably null
R8356:Dnah9	UTSW	11	66,156,938 (GRCm38)	missense	probably damaging	0.99
R8456:Dnah9	UTSW	11	66,156,938 (GRCm38)	missense	probably damaging	0.99
R8468:Dnah9	UTSW	11	65,831,730 (GRCm38)	missense	probably benign	0.00
R8721:Dnah9	UTSW	11	66,095,298 (GRCm38)	missense	probably damaging	1.00
R8747:Dnah9	UTSW	11	65,927,990 (GRCm38)	missense	possibly damaging	0.69
R8798:Dnah9	UTSW	11	65,905,231 (GRCm38)	missense	probably damaging	0.99
R8806:Dnah9	UTSW	11	65,859,483 (GRCm38)	missense	probably damaging	1.00
R8826:Dnah9	UTSW	11	65,849,916 (GRCm38)	missense	probably benign	0.13
R8837:Dnah9	UTSW	11	65,855,234 (GRCm38)	missense	possibly damaging	0.72
R8886:Dnah9	UTSW	11	66,053,014 (GRCm38)	missense	probably damaging	1.00
R8887:Dnah9	UTSW	11	65,855,384 (GRCm38)	missense	probably benign	0.01
R8921:Dnah9	UTSW	11	65,911,921 (GRCm38)	missense	probably benign
R8933:Dnah9	UTSW	11	65,855,252 (GRCm38)	missense	possibly damaging	0.88
R8949:Dnah9	UTSW	11	66,168,400 (GRCm38)	missense	possibly damaging	0.91
R8967:Dnah9	UTSW	11	66,125,112 (GRCm38)	critical splice donor site	probably null
R8979:Dnah9	UTSW	11	66,005,152 (GRCm38)	missense	probably benign
R8991:Dnah9	UTSW	11	65,886,680 (GRCm38)	missense	probably damaging	0.96
R9016:Dnah9	UTSW	11	66,108,030 (GRCm38)	missense	probably damaging	0.99
R9025:Dnah9	UTSW	11	66,005,825 (GRCm38)	missense	probably damaging	1.00
R9043:Dnah9	UTSW	11	65,954,854 (GRCm38)	missense
R9047:Dnah9	UTSW	11	66,072,099 (GRCm38)	missense	possibly damaging	0.89
R9076:Dnah9	UTSW	11	66,117,638 (GRCm38)	missense	probably benign	0.21
R9113:Dnah9	UTSW	11	65,989,887 (GRCm38)	missense	probably damaging	1.00
R9152:Dnah9	UTSW	11	66,130,631 (GRCm38)	missense	probably damaging	1.00
R9187:Dnah9	UTSW	11	66,005,146 (GRCm38)	missense	probably benign
R9198:Dnah9	UTSW	11	65,955,744 (GRCm38)	missense	probably benign	0.02
R9203:Dnah9	UTSW	11	65,855,287 (GRCm38)	missense	possibly damaging	0.58
R9234:Dnah9	UTSW	11	66,033,925 (GRCm38)	missense	possibly damaging	0.68
R9245:Dnah9	UTSW	11	65,895,905 (GRCm38)	missense	probably benign	0.30
R9265:Dnah9	UTSW	11	65,841,255 (GRCm38)	missense	probably benign	0.01
R9307:Dnah9	UTSW	11	66,085,474 (GRCm38)	missense	probably benign	0.14
R9336:Dnah9	UTSW	11	65,870,949 (GRCm38)	missense	probably damaging	1.00
R9386:Dnah9	UTSW	11	65,947,542 (GRCm38)	missense	probably damaging	1.00
R9498:Dnah9	UTSW	11	65,848,373 (GRCm38)	missense	probably damaging	0.99
R9508:Dnah9	UTSW	11	65,834,263 (GRCm38)	missense	probably damaging	1.00
R9524:Dnah9	UTSW	11	66,085,483 (GRCm38)	missense	possibly damaging	0.92
R9577:Dnah9	UTSW	11	65,976,521 (GRCm38)	missense	probably benign	0.00
R9583:Dnah9	UTSW	11	65,965,681 (GRCm38)	missense	probably damaging	1.00
R9587:Dnah9	UTSW	11	66,108,391 (GRCm38)	missense	probably null	0.92
R9612:Dnah9	UTSW	11	65,927,649 (GRCm38)	missense	probably benign	0.00
R9748:Dnah9	UTSW	11	66,085,464 (GRCm38)	missense	possibly damaging	0.51
R9749:Dnah9	UTSW	11	66,095,376 (GRCm38)	missense	probably damaging	1.00
R9759:Dnah9	UTSW	11	66,075,118 (GRCm38)	missense	probably null	0.93
R9784:Dnah9	UTSW	11	66,085,134 (GRCm38)	missense	probably damaging	0.99
V3553:Dnah9	UTSW	11	65,970,076 (GRCm38)	missense	probably damaging	1.00
X0027:Dnah9	UTSW	11	66,085,479 (GRCm38)	missense	probably benign	0.07
X0028:Dnah9	UTSW	11	65,990,452 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah9	UTSW	11	65,970,084 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah9	UTSW	11	65,927,853 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah9	UTSW	11	65,895,972 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah9	UTSW	11	66,072,835 (GRCm38)	missense	probably damaging	1.00
Z1176:Dnah9	UTSW	11	66,037,474 (GRCm38)	missense	probably damaging	1.00
Z1177:Dnah9	UTSW	11	66,126,650 (GRCm38)	missense	probably damaging	1.00
Z1186:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1186:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1187:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1187:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1188:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1188:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1189:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1189:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1190:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1190:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1191:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1191:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign
Z1192:Dnah9	UTSW	11	66,147,381 (GRCm38)	missense	probably benign
Z1192:Dnah9	UTSW	11	66,085,174 (GRCm38)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- GCCATGAAGGAGACAATGACTC -3'
(R):5'- AAAAGCAGTGTTCTTCCCAGC -3'

Sequencing Primer
(F):5'- TCTGAAACAGTGACATCATCCTGG -3'
(R):5'- AGAAAATGGTTCCTTTCCTGAGG -3'

Posted On

2019-06-26