Incidental Mutation 'R7231:Umodl1'
| ID |
562507 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Umodl1
|
| Ensembl Gene |
ENSMUSG00000054134 |
| Gene Name |
uromodulin-like 1 |
| Synonyms |
D17Ertd488e |
| MMRRC Submission |
045342-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7231 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
31173614-31229684 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 31205090 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Isoleucine
at position 562
(V562I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000067443
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066554]
[ENSMUST00000066981]
[ENSMUST00000114555]
|
| AlphaFold |
Q5DID3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066554
AA Change: V562I
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000067443
Gene: ENSMUSG00000054134
AA Change: V562I
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066981
AA Change: V562I
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000065470
Gene: ENSMUSG00000054134
AA Change: V562I
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
8.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
8.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
619 |
632 |
N/A |
INTRINSIC |
|
SEA
|
706 |
821 |
8.88e-2 |
SMART |
|
EGF
|
818 |
859 |
4.26e0 |
SMART |
|
ZP
|
909 |
1152 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1186 |
1208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000114555
AA Change: V562I
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000110202
Gene: ENSMUSG00000054134
AA Change: V562I
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
9.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
9.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1203 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
98% (78/80) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca13 |
A |
T |
11: 9,244,175 (GRCm39) |
T2013S |
probably benign |
Het |
| Ablim3 |
A |
G |
18: 61,938,135 (GRCm39) |
|
probably null |
Het |
| Acvrl1 |
T |
A |
15: 101,034,104 (GRCm39) |
C206* |
probably null |
Het |
| Adamts15 |
C |
A |
9: 30,817,454 (GRCm39) |
R541S |
probably damaging |
Het |
| Add3 |
A |
G |
19: 53,221,577 (GRCm39) |
I230V |
probably benign |
Het |
| Ankrd27 |
A |
G |
7: 35,327,871 (GRCm39) |
D742G |
possibly damaging |
Het |
| Asxl3 |
A |
G |
18: 22,650,597 (GRCm39) |
E862G |
probably damaging |
Het |
| Asxl3 |
A |
T |
18: 22,544,556 (GRCm39) |
|
probably null |
Het |
| Atp2b2 |
G |
A |
6: 113,742,693 (GRCm39) |
T798M |
possibly damaging |
Het |
| Car12 |
T |
C |
9: 66,659,599 (GRCm39) |
I208T |
probably damaging |
Het |
| Cgn |
T |
A |
3: 94,680,502 (GRCm39) |
Q600L |
probably damaging |
Het |
| Cgnl1 |
C |
T |
9: 71,539,927 (GRCm39) |
A1106T |
probably benign |
Het |
| Cmtr2 |
T |
C |
8: 110,949,178 (GRCm39) |
V496A |
probably benign |
Het |
| Cplx4 |
C |
A |
18: 66,090,123 (GRCm39) |
D99Y |
probably damaging |
Het |
| Cyfip2 |
T |
C |
11: 46,114,963 (GRCm39) |
T915A |
probably benign |
Het |
| Cyp4a32 |
T |
C |
4: 115,466,894 (GRCm39) |
L193P |
probably damaging |
Het |
| Dennd5b |
C |
T |
6: 148,946,102 (GRCm39) |
R503Q |
probably damaging |
Het |
| Depdc5 |
C |
A |
5: 33,059,209 (GRCm39) |
Q303K |
possibly damaging |
Het |
| Dlx1 |
T |
A |
2: 71,362,840 (GRCm39) |
M249K |
possibly damaging |
Het |
| Dnah10 |
A |
T |
5: 124,890,892 (GRCm39) |
E3218V |
probably benign |
Het |
| Dnah9 |
T |
C |
11: 65,856,473 (GRCm39) |
D2896G |
probably damaging |
Het |
| Dtx4 |
C |
A |
19: 12,447,022 (GRCm39) |
G557* |
probably null |
Het |
| Eps8l2 |
A |
G |
7: 140,940,305 (GRCm39) |
N512D |
probably damaging |
Het |
| Fam20a |
T |
C |
11: 109,612,201 (GRCm39) |
D114G |
possibly damaging |
Het |
| Fbln1 |
T |
C |
15: 85,090,353 (GRCm39) |
S7P |
unknown |
Het |
| Fli1 |
T |
C |
9: 32,335,484 (GRCm39) |
E316G |
probably damaging |
Het |
| Fmn2 |
CCCTCCTCTCCCTGGAATGGGAATACCTCCCCCACCTCCTCTCCCTGGAATGGGAATACCTCCCCCACCTCCTCTCCCTGGAATGGGAATATCTCCCCTACCTCCTCTCCCTGGAATGGGAATACCTCC |
CCCTCCTCTCCCTGGAATGGGAATACCTCCCCCACCTCCTCTCCCTGGAATGGGAATATCTCCCCTACCTCCTCTCCCTGGAATGGGAATACCTCC |
1: 174,436,769 (GRCm39) |
|
probably benign |
Het |
| Haus8 |
G |
A |
8: 71,705,781 (GRCm39) |
T302I |
probably benign |
Het |
| Hmcn1 |
T |
C |
1: 150,514,627 (GRCm39) |
I3582V |
probably benign |
Het |
| Hnrnpul1 |
G |
A |
7: 25,447,842 (GRCm39) |
Q161* |
probably null |
Het |
| Hsf4 |
C |
T |
8: 105,998,779 (GRCm39) |
A223V |
probably damaging |
Het |
| Ighg2c |
A |
G |
12: 113,251,636 (GRCm39) |
W164R |
|
Het |
| Isl1 |
A |
G |
13: 116,439,826 (GRCm39) |
V174A |
probably benign |
Het |
| Itih4 |
A |
T |
14: 30,618,571 (GRCm39) |
I661F |
probably benign |
Het |
| Klhl14 |
A |
T |
18: 21,785,193 (GRCm39) |
L78Q |
probably damaging |
Het |
| L3mbtl3 |
T |
A |
10: 26,215,180 (GRCm39) |
I177F |
unknown |
Het |
| Lingo3 |
T |
A |
10: 80,670,938 (GRCm39) |
T331S |
possibly damaging |
Het |
| Lrrc36 |
T |
C |
8: 106,187,689 (GRCm39) |
V535A |
possibly damaging |
Het |
| Mapk8ip2 |
T |
G |
15: 89,342,279 (GRCm39) |
S497A |
probably benign |
Het |
| Mbip |
A |
G |
12: 56,384,547 (GRCm39) |
|
probably null |
Het |
| Nelfa |
C |
T |
5: 34,056,169 (GRCm39) |
G498D |
probably damaging |
Het |
| Nherf2 |
C |
T |
17: 24,869,078 (GRCm39) |
R16H |
probably damaging |
Het |
| Nlrc5 |
T |
A |
8: 95,248,433 (GRCm39) |
|
probably null |
Het |
| Or2ag2b |
A |
T |
7: 106,417,650 (GRCm39) |
Y120F |
probably damaging |
Het |
| Or4f59 |
A |
T |
2: 111,872,711 (GRCm39) |
V222D |
probably damaging |
Het |
| Or56a3 |
T |
C |
7: 104,734,994 (GRCm39) |
S24P |
possibly damaging |
Het |
| Or7e171-ps1 |
T |
A |
9: 19,852,855 (GRCm39) |
T294S |
unknown |
Het |
| Pde2a |
A |
G |
7: 101,155,160 (GRCm39) |
Y567C |
probably damaging |
Het |
| Pdia4 |
A |
T |
6: 47,777,891 (GRCm39) |
F367Y |
probably benign |
Het |
| Pkdrej |
C |
A |
15: 85,700,389 (GRCm39) |
C1849F |
possibly damaging |
Het |
| Plekhj1 |
T |
G |
10: 80,633,492 (GRCm39) |
T52P |
probably damaging |
Het |
| Ppp2r5d |
A |
T |
17: 46,994,986 (GRCm39) |
Y572N |
probably benign |
Het |
| Prkcq |
T |
A |
2: 11,295,262 (GRCm39) |
Y570* |
probably null |
Het |
| Ptpn3 |
T |
A |
4: 57,245,062 (GRCm39) |
D226V |
probably damaging |
Het |
| Rab1b |
A |
G |
19: 5,155,229 (GRCm39) |
S22P |
probably damaging |
Het |
| Ralgapa1 |
A |
G |
12: 55,650,976 (GRCm39) |
S2060P |
probably damaging |
Het |
| Rnf148 |
G |
T |
6: 23,654,890 (GRCm39) |
S35R |
probably benign |
Het |
| Runx2 |
G |
A |
17: 45,125,079 (GRCm39) |
P80L |
probably damaging |
Het |
| Samd15 |
T |
A |
12: 87,247,818 (GRCm39) |
S168T |
possibly damaging |
Het |
| Slc26a4 |
T |
A |
12: 31,597,945 (GRCm39) |
N167I |
probably damaging |
Het |
| Slc39a1 |
C |
A |
3: 90,159,097 (GRCm39) |
H141Q |
probably benign |
Het |
| Snx21 |
T |
C |
2: 164,628,121 (GRCm39) |
S46P |
probably benign |
Het |
| Strip2 |
A |
G |
6: 29,944,486 (GRCm39) |
S657G |
probably damaging |
Het |
| Stxbp3 |
G |
A |
3: 108,708,125 (GRCm39) |
P392L |
probably damaging |
Het |
| Suclg1 |
G |
A |
6: 73,240,954 (GRCm39) |
R161H |
probably benign |
Het |
| Tas1r3 |
T |
C |
4: 155,947,283 (GRCm39) |
Y134C |
probably damaging |
Het |
| Tgif1 |
T |
A |
17: 71,153,168 (GRCm39) |
Q114L |
probably damaging |
Het |
| Tll2 |
A |
G |
19: 41,074,673 (GRCm39) |
F964L |
probably benign |
Het |
| Tmem181a |
T |
C |
17: 6,348,195 (GRCm39) |
S247P |
possibly damaging |
Het |
| Trav23 |
A |
T |
14: 54,215,025 (GRCm39) |
R79S |
probably damaging |
Het |
| Trf |
C |
A |
9: 103,102,347 (GRCm39) |
C177F |
probably damaging |
Het |
| Triml1 |
T |
C |
8: 43,589,408 (GRCm39) |
Y260C |
probably benign |
Het |
| Tulp4 |
T |
C |
17: 6,286,510 (GRCm39) |
F1513L |
probably benign |
Het |
| Ush2a |
A |
G |
1: 188,491,960 (GRCm39) |
K3083R |
possibly damaging |
Het |
| Vmn1r74 |
A |
T |
7: 11,580,888 (GRCm39) |
I63F |
probably benign |
Het |
| Vmn2r38 |
C |
T |
7: 9,100,637 (GRCm39) |
C43Y |
possibly damaging |
Het |
| Vmn2r50 |
A |
T |
7: 9,787,010 (GRCm39) |
N32K |
probably benign |
Het |
| Vps13d |
A |
G |
4: 144,784,032 (GRCm39) |
V3914A |
|
Het |
| Vwa5b2 |
A |
G |
16: 20,422,878 (GRCm39) |
T984A |
probably benign |
Het |
| Zc3h3 |
C |
T |
15: 75,712,231 (GRCm39) |
V77M |
probably damaging |
Het |
| Zfp397 |
A |
T |
18: 24,093,415 (GRCm39) |
H300L |
probably damaging |
Het |
| Zfp950 |
G |
A |
19: 61,107,650 (GRCm39) |
R478C |
probably benign |
Het |
|
| Other mutations in Umodl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00915:Umodl1
|
APN |
17 |
31,227,724 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL01344:Umodl1
|
APN |
17 |
31,215,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01529:Umodl1
|
APN |
17 |
31,215,233 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01609:Umodl1
|
APN |
17 |
31,217,800 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01625:Umodl1
|
APN |
17 |
31,215,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01877:Umodl1
|
APN |
17 |
31,201,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01977:Umodl1
|
APN |
17 |
31,192,742 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02063:Umodl1
|
APN |
17 |
31,206,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL02160:Umodl1
|
APN |
17 |
31,205,091 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02252:Umodl1
|
APN |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02427:Umodl1
|
APN |
17 |
31,187,415 (GRCm39) |
splice site |
probably benign |
|
|
IGL02496:Umodl1
|
APN |
17 |
31,217,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02633:Umodl1
|
APN |
17 |
31,208,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03271:Umodl1
|
APN |
17 |
31,205,473 (GRCm39) |
nonsense |
probably null |
|
|
IGL03392:Umodl1
|
APN |
17 |
31,215,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Disquieting
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
floored
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7231_umodl1_507
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
surprising
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
unsettling
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
G1citation:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
PIT4468001:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0653:Umodl1
|
UTSW |
17 |
31,203,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0831:Umodl1
|
UTSW |
17 |
31,215,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1078:Umodl1
|
UTSW |
17 |
31,178,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1166:Umodl1
|
UTSW |
17 |
31,221,772 (GRCm39) |
splice site |
probably benign |
|
|
R1231:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1459:Umodl1
|
UTSW |
17 |
31,205,478 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1459:Umodl1
|
UTSW |
17 |
31,201,232 (GRCm39) |
splice site |
probably benign |
|
|
R1510:Umodl1
|
UTSW |
17 |
31,178,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1654:Umodl1
|
UTSW |
17 |
31,206,942 (GRCm39) |
missense |
probably benign |
|
|
R1757:Umodl1
|
UTSW |
17 |
31,227,674 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1781:Umodl1
|
UTSW |
17 |
31,187,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1873:Umodl1
|
UTSW |
17 |
31,201,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1911:Umodl1
|
UTSW |
17 |
31,211,128 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R1917:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1918:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2057:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2058:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2089:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2431:Umodl1
|
UTSW |
17 |
31,211,062 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2903:Umodl1
|
UTSW |
17 |
31,211,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3032:Umodl1
|
UTSW |
17 |
31,208,502 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3956:Umodl1
|
UTSW |
17 |
31,221,837 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3975:Umodl1
|
UTSW |
17 |
31,203,763 (GRCm39) |
nonsense |
probably null |
|
|
R4207:Umodl1
|
UTSW |
17 |
31,178,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4287:Umodl1
|
UTSW |
17 |
31,207,039 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4452:Umodl1
|
UTSW |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4684:Umodl1
|
UTSW |
17 |
31,217,088 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4769:Umodl1
|
UTSW |
17 |
31,202,976 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4887:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4888:Umodl1
|
UTSW |
17 |
31,218,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4978:Umodl1
|
UTSW |
17 |
31,205,055 (GRCm39) |
missense |
probably benign |
|
|
R4993:Umodl1
|
UTSW |
17 |
31,205,459 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5241:Umodl1
|
UTSW |
17 |
31,203,066 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5254:Umodl1
|
UTSW |
17 |
31,199,333 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5454:Umodl1
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5456:Umodl1
|
UTSW |
17 |
31,201,263 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5754:Umodl1
|
UTSW |
17 |
31,213,761 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6189:Umodl1
|
UTSW |
17 |
31,215,256 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6222:Umodl1
|
UTSW |
17 |
31,221,866 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6289:Umodl1
|
UTSW |
17 |
31,201,325 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6432:Umodl1
|
UTSW |
17 |
31,205,121 (GRCm39) |
missense |
probably benign |
0.38 |
|
R6478:Umodl1
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6702:Umodl1
|
UTSW |
17 |
31,205,273 (GRCm39) |
splice site |
probably null |
|
|
R6822:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
R6999:Umodl1
|
UTSW |
17 |
31,218,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7067:Umodl1
|
UTSW |
17 |
31,201,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7123:Umodl1
|
UTSW |
17 |
31,201,318 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7219:Umodl1
|
UTSW |
17 |
31,201,236 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7234:Umodl1
|
UTSW |
17 |
31,205,595 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7297:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7392:Umodl1
|
UTSW |
17 |
31,201,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7401:Umodl1
|
UTSW |
17 |
31,217,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7461:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7594:Umodl1
|
UTSW |
17 |
31,173,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7613:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7763:Umodl1
|
UTSW |
17 |
31,205,430 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7797:Umodl1
|
UTSW |
17 |
31,178,125 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7832:Umodl1
|
UTSW |
17 |
31,192,666 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7954:Umodl1
|
UTSW |
17 |
31,205,361 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8088:Umodl1
|
UTSW |
17 |
31,192,770 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8111:Umodl1
|
UTSW |
17 |
31,190,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8314:Umodl1
|
UTSW |
17 |
31,203,806 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8826:Umodl1
|
UTSW |
17 |
31,202,958 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9067:Umodl1
|
UTSW |
17 |
31,192,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9091:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9099:Umodl1
|
UTSW |
17 |
31,178,147 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9270:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9341:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9343:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9400:Umodl1
|
UTSW |
17 |
31,215,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9569:Umodl1
|
UTSW |
17 |
31,217,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9615:Umodl1
|
UTSW |
17 |
31,217,152 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9787:Umodl1
|
UTSW |
17 |
31,178,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCTCTCCAGACTCACAAAGGG -3'
(R):5'- AGGGAACAGAGCTTGTCACC -3'
Sequencing Primer
(F):5'- TCTCCAGACTCACAAAGGGTTGAG -3'
(R):5'- AGAGCTTGTCACCCCACTG -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation