Incidental Mutation 'R7238:Urb1'
| ID |
563035 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Urb1
|
| Ensembl Gene |
ENSMUSG00000039929 |
| Gene Name |
URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| Synonyms |
5730405K23Rik, 4921511H13Rik |
| MMRRC Submission |
045345-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7238 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
90548415-90607301 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 90549003 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 2235
(D2235G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000114717
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038197]
[ENSMUST00000125429]
[ENSMUST00000138984]
[ENSMUST00000140920]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000038197
|
| SMART Domains |
Protein: ENSMUSP00000043890
Gene: ENSMUSG00000039956
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:MRAP
|
1 |
90 |
1.7e-49 |
PFAM |
|
low complexity region
|
115 |
127 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125429
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000138984
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000140920
AA Change: D2235G
PolyPhen 2
Score 0.880 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000114717
Gene: ENSMUSG00000039929
AA Change: D2235G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
20 |
N/A |
INTRINSIC |
|
Pfam:Npa1
|
78 |
396 |
1.5e-86 |
PFAM |
|
low complexity region
|
751 |
761 |
N/A |
INTRINSIC |
|
low complexity region
|
955 |
966 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1137 |
N/A |
INTRINSIC |
|
low complexity region
|
1360 |
1375 |
N/A |
INTRINSIC |
|
Pfam:NopRA1
|
1670 |
1859 |
3.6e-60 |
PFAM |
|
low complexity region
|
2029 |
2040 |
N/A |
INTRINSIC |
|
low complexity region
|
2092 |
2111 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.9%
|
| Validation Efficiency |
97% (104/107) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 106 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110002E22Rik |
A |
T |
3: 137,775,712 (GRCm39) |
T1634S |
probably damaging |
Het |
| Adgrl1 |
T |
A |
8: 84,665,693 (GRCm39) |
M1460K |
probably damaging |
Het |
| Adig |
T |
A |
2: 158,347,773 (GRCm39) |
L29Q |
unknown |
Het |
| Adnp |
T |
G |
2: 168,025,887 (GRCm39) |
K469N |
probably damaging |
Het |
| Akap3 |
A |
G |
6: 126,842,200 (GRCm39) |
D273G |
probably benign |
Het |
| Albfm1 |
A |
T |
5: 90,727,519 (GRCm39) |
Y379F |
probably damaging |
Het |
| Ankrd34b |
T |
C |
13: 92,575,139 (GRCm39) |
Y124H |
possibly damaging |
Het |
| Ap2b1 |
T |
G |
11: 83,223,948 (GRCm39) |
F221C |
possibly damaging |
Het |
| Atp2c2 |
A |
G |
8: 120,469,160 (GRCm39) |
I358V |
possibly damaging |
Het |
| BC051665 |
G |
A |
13: 60,930,536 (GRCm39) |
T272I |
probably benign |
Het |
| Cdan1 |
G |
T |
2: 120,560,783 (GRCm39) |
A262E |
probably benign |
Het |
| Ces1d |
C |
T |
8: 93,904,763 (GRCm39) |
V326I |
probably benign |
Het |
| Chd3 |
T |
C |
11: 69,254,873 (GRCm39) |
R156G |
probably benign |
Het |
| Clip1 |
C |
T |
5: 123,751,328 (GRCm39) |
E818K |
|
Het |
| Col6a4 |
C |
T |
9: 105,877,519 (GRCm39) |
V2153M |
probably damaging |
Het |
| Crlf3 |
T |
C |
11: 79,947,351 (GRCm39) |
N296D |
possibly damaging |
Het |
| Cstdc6 |
C |
T |
16: 36,142,193 (GRCm39) |
G61D |
probably benign |
Het |
| D130052B06Rik |
A |
G |
11: 33,573,594 (GRCm39) |
I109V |
probably benign |
Het |
| Dcaf5 |
G |
T |
12: 80,385,483 (GRCm39) |
T881K |
probably benign |
Het |
| Dennd4a |
C |
A |
9: 64,769,238 (GRCm39) |
T408K |
probably damaging |
Het |
| Dnaaf9 |
C |
A |
2: 130,648,708 (GRCm39) |
R258L |
unknown |
Het |
| Dnah2 |
A |
G |
11: 69,349,972 (GRCm39) |
|
probably null |
Het |
| Eif1ad8 |
A |
T |
12: 87,564,006 (GRCm39) |
K114* |
probably null |
Het |
| Eif2ak2 |
C |
T |
17: 79,173,760 (GRCm39) |
V273I |
probably benign |
Het |
| Elac1 |
C |
T |
18: 73,872,359 (GRCm39) |
G212D |
probably damaging |
Het |
| Ercc6l2 |
A |
G |
13: 64,013,798 (GRCm39) |
D623G |
probably damaging |
Het |
| Exo1 |
T |
C |
1: 175,716,413 (GRCm39) |
F177L |
probably damaging |
Het |
| Fat4 |
A |
G |
3: 38,944,562 (GRCm39) |
T1152A |
probably benign |
Het |
| Fbxl12 |
G |
T |
9: 20,529,709 (GRCm39) |
|
probably null |
Het |
| Fbxo43 |
T |
C |
15: 36,151,971 (GRCm39) |
Y582C |
probably damaging |
Het |
| Fsip2 |
T |
A |
2: 82,812,484 (GRCm39) |
N2934K |
possibly damaging |
Het |
| Gna12 |
A |
G |
5: 140,815,847 (GRCm39) |
S69P |
probably damaging |
Het |
| Gpatch8 |
C |
A |
11: 102,369,354 (GRCm39) |
G1395C |
probably damaging |
Het |
| Gpr137c |
A |
G |
14: 45,516,148 (GRCm39) |
Y294C |
probably damaging |
Het |
| Greb1 |
A |
G |
12: 16,724,673 (GRCm39) |
S1834P |
probably damaging |
Het |
| Grin2b |
T |
C |
6: 135,757,249 (GRCm39) |
D404G |
probably damaging |
Het |
| Hectd2 |
A |
T |
19: 36,574,478 (GRCm39) |
N236I |
probably damaging |
Het |
| Hhip |
C |
T |
8: 80,713,641 (GRCm39) |
V562I |
probably benign |
Het |
| Hipk2 |
G |
T |
6: 38,692,992 (GRCm39) |
T867N |
probably benign |
Het |
| Hmgcl |
T |
C |
4: 135,689,424 (GRCm39) |
V294A |
possibly damaging |
Het |
| Hnrnpl |
T |
A |
7: 28,513,400 (GRCm39) |
F158I |
|
Het |
| Hspa5 |
T |
C |
2: 34,662,383 (GRCm39) |
V17A |
unknown |
Het |
| Hspg2 |
T |
C |
4: 137,235,704 (GRCm39) |
V168A |
probably damaging |
Het |
| Idh1 |
A |
G |
1: 65,205,284 (GRCm39) |
F227S |
probably damaging |
Het |
| Iigp1c |
A |
G |
18: 60,379,355 (GRCm39) |
S297G |
possibly damaging |
Het |
| Immp2l |
T |
C |
12: 41,160,915 (GRCm39) |
V71A |
possibly damaging |
Het |
| Iqce |
G |
A |
5: 140,675,713 (GRCm39) |
R193* |
probably null |
Het |
| Kcnq5 |
T |
C |
1: 21,472,526 (GRCm39) |
D907G |
probably benign |
Het |
| Krt17 |
T |
A |
11: 100,148,613 (GRCm39) |
T306S |
probably benign |
Het |
| Lhx3 |
T |
C |
2: 26,093,009 (GRCm39) |
D149G |
probably damaging |
Het |
| Lrrc73 |
G |
A |
17: 46,565,488 (GRCm39) |
R73H |
probably damaging |
Het |
| Mgat5b |
T |
C |
11: 116,875,809 (GRCm39) |
S678P |
probably benign |
Het |
| Mink1 |
T |
C |
11: 70,502,305 (GRCm39) |
|
probably null |
Het |
| Mroh5 |
T |
G |
15: 73,663,278 (GRCm39) |
|
probably null |
Het |
| Muc5ac |
T |
A |
7: 141,363,254 (GRCm39) |
H2188Q |
unknown |
Het |
| Muc5ac |
G |
C |
7: 141,363,424 (GRCm39) |
|
probably benign |
Het |
| Musk |
G |
A |
4: 58,344,312 (GRCm39) |
G305D |
probably benign |
Het |
| Mx1 |
A |
G |
16: 97,249,496 (GRCm39) |
I347T |
unknown |
Het |
| Mybbp1a |
G |
T |
11: 72,334,338 (GRCm39) |
V198F |
probably damaging |
Het |
| Mycbp2 |
A |
G |
14: 103,393,733 (GRCm39) |
S2943P |
probably damaging |
Het |
| Myo18a |
G |
A |
11: 77,733,059 (GRCm39) |
R1363K |
probably damaging |
Het |
| Nav3 |
T |
A |
10: 109,689,185 (GRCm39) |
D364V |
possibly damaging |
Het |
| Or13g1 |
T |
C |
7: 85,955,799 (GRCm39) |
H174R |
probably damaging |
Het |
| Or14j6 |
T |
C |
17: 38,215,328 (GRCm39) |
L297S |
probably benign |
Het |
| Or1e26 |
A |
T |
11: 73,480,561 (GRCm39) |
M1K |
probably null |
Het |
| Or1j13 |
T |
A |
2: 36,369,726 (GRCm39) |
N139Y |
possibly damaging |
Het |
| Or5k15 |
T |
A |
16: 58,710,252 (GRCm39) |
E110D |
probably damaging |
Het |
| Pecr |
T |
C |
1: 72,298,592 (GRCm39) |
D276G |
probably damaging |
Het |
| Pkd1l3 |
GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA |
GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA |
8: 110,350,827 (GRCm39) |
|
probably benign |
Het |
| Ppp1cb |
A |
T |
5: 32,648,376 (GRCm39) |
T320S |
probably benign |
Het |
| Ppp1r9a |
G |
T |
6: 5,159,716 (GRCm39) |
K1084N |
probably damaging |
Het |
| Prdm2 |
A |
G |
4: 142,862,391 (GRCm39) |
S300P |
probably benign |
Het |
| Prkg1 |
C |
T |
19: 30,602,090 (GRCm39) |
V389I |
probably damaging |
Het |
| Psg25 |
C |
T |
7: 18,266,127 (GRCm39) |
|
probably benign |
Het |
| Ptpn6 |
A |
G |
6: 124,698,821 (GRCm39) |
S498P |
possibly damaging |
Het |
| Pus3 |
A |
G |
9: 35,477,965 (GRCm39) |
H399R |
probably benign |
Het |
| Pus7 |
T |
C |
5: 23,983,450 (GRCm39) |
T6A |
probably benign |
Het |
| Rnf169 |
A |
G |
7: 99,574,954 (GRCm39) |
V547A |
probably benign |
Het |
| Rsf1 |
GGCGGCGGC |
GGCGGCGGCCGCGGCGGC |
7: 97,229,128 (GRCm39) |
|
probably benign |
Het |
| Ryr1 |
C |
T |
7: 28,794,807 (GRCm39) |
D1194N |
probably benign |
Het |
| Scn5a |
T |
C |
9: 119,320,610 (GRCm39) |
M1490V |
possibly damaging |
Het |
| Sec23b |
A |
G |
2: 144,432,258 (GRCm39) |
D756G |
possibly damaging |
Het |
| Selenoo |
T |
A |
15: 88,973,427 (GRCm39) |
M39K |
probably benign |
Het |
| Septin8 |
T |
G |
11: 53,427,519 (GRCm39) |
V246G |
possibly damaging |
Het |
| Serpina3k |
T |
A |
12: 104,309,367 (GRCm39) |
N270K |
probably damaging |
Het |
| Setd5 |
G |
A |
6: 113,098,091 (GRCm39) |
R710H |
probably damaging |
Het |
| Sirt4 |
A |
T |
5: 115,621,049 (GRCm39) |
I41N |
possibly damaging |
Het |
| Slc26a9 |
T |
A |
1: 131,686,556 (GRCm39) |
Y425* |
probably null |
Het |
| Slc4a9 |
A |
G |
18: 36,662,773 (GRCm39) |
E176G |
probably benign |
Het |
| Speer1m |
T |
C |
5: 11,970,712 (GRCm39) |
I127T |
|
Het |
| Spidr |
A |
T |
16: 15,784,680 (GRCm39) |
W463R |
probably benign |
Het |
| Tenm4 |
G |
A |
7: 96,202,703 (GRCm39) |
R106H |
probably benign |
Het |
| Tmcc1 |
G |
A |
6: 116,111,198 (GRCm39) |
Q28* |
probably null |
Het |
| Tmem52b |
A |
G |
6: 129,493,651 (GRCm39) |
E88G |
probably damaging |
Het |
| Trpc7 |
A |
T |
13: 56,974,710 (GRCm39) |
I402K |
probably benign |
Het |
| Tshz3 |
T |
C |
7: 36,469,522 (GRCm39) |
Y504H |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,542,549 (GRCm39) |
E33479G |
possibly damaging |
Het |
| Ttn |
G |
A |
2: 76,711,672 (GRCm39) |
R8290C |
unknown |
Het |
| Usp10 |
T |
C |
8: 120,668,283 (GRCm39) |
F195L |
probably benign |
Het |
| Vmn1r31 |
A |
T |
6: 58,449,858 (GRCm39) |
F2L |
|
Het |
| Vmn2r109 |
C |
T |
17: 20,761,336 (GRCm39) |
V674M |
probably damaging |
Het |
| Vmn2r12 |
G |
A |
5: 109,245,655 (GRCm39) |
P26S |
possibly damaging |
Het |
| Vmn2r61 |
T |
A |
7: 41,916,629 (GRCm39) |
M414K |
possibly damaging |
Het |
| Yipf3 |
T |
C |
17: 46,562,585 (GRCm39) |
V330A |
probably benign |
Het |
| Zic4 |
A |
T |
9: 91,261,450 (GRCm39) |
H235L |
probably benign |
Het |
| Zxdc |
T |
A |
6: 90,346,642 (GRCm39) |
W16R |
unknown |
Het |
|
| Other mutations in Urb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00715:Urb1
|
APN |
16 |
90,550,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00915:Urb1
|
APN |
16 |
90,575,986 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL01108:Urb1
|
APN |
16 |
90,589,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01122:Urb1
|
APN |
16 |
90,601,346 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL01387:Urb1
|
APN |
16 |
90,554,649 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL01484:Urb1
|
APN |
16 |
90,574,448 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL01606:Urb1
|
APN |
16 |
90,557,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01989:Urb1
|
APN |
16 |
90,566,474 (GRCm39) |
splice site |
probably benign |
|
|
IGL02516:Urb1
|
APN |
16 |
90,569,583 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
IGL03018:Urb1
|
APN |
16 |
90,585,044 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03165:Urb1
|
APN |
16 |
90,577,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03216:Urb1
|
APN |
16 |
90,585,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
H8562:Urb1
|
UTSW |
16 |
90,566,357 (GRCm39) |
missense |
probably benign |
0.08 |
|
H8786:Urb1
|
UTSW |
16 |
90,566,357 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0064:Urb1
|
UTSW |
16 |
90,576,028 (GRCm39) |
missense |
probably benign |
|
|
R0064:Urb1
|
UTSW |
16 |
90,576,028 (GRCm39) |
missense |
probably benign |
|
|
R0359:Urb1
|
UTSW |
16 |
90,588,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0386:Urb1
|
UTSW |
16 |
90,593,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0508:Urb1
|
UTSW |
16 |
90,580,150 (GRCm39) |
splice site |
probably benign |
|
|
R0517:Urb1
|
UTSW |
16 |
90,574,310 (GRCm39) |
nonsense |
probably null |
|
|
R0704:Urb1
|
UTSW |
16 |
90,573,095 (GRCm39) |
missense |
probably benign |
0.31 |
|
R0755:Urb1
|
UTSW |
16 |
90,576,026 (GRCm39) |
missense |
probably benign |
|
|
R0755:Urb1
|
UTSW |
16 |
90,570,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0783:Urb1
|
UTSW |
16 |
90,607,185 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R0833:Urb1
|
UTSW |
16 |
90,592,336 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0836:Urb1
|
UTSW |
16 |
90,592,336 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0970:Urb1
|
UTSW |
16 |
90,566,335 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1144:Urb1
|
UTSW |
16 |
90,573,206 (GRCm39) |
splice site |
probably null |
|
|
R1344:Urb1
|
UTSW |
16 |
90,566,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1418:Urb1
|
UTSW |
16 |
90,566,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1453:Urb1
|
UTSW |
16 |
90,593,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1470:Urb1
|
UTSW |
16 |
90,548,902 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1470:Urb1
|
UTSW |
16 |
90,548,902 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1520:Urb1
|
UTSW |
16 |
90,571,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1521:Urb1
|
UTSW |
16 |
90,550,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1598:Urb1
|
UTSW |
16 |
90,574,328 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1617:Urb1
|
UTSW |
16 |
90,557,340 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1625:Urb1
|
UTSW |
16 |
90,570,936 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1640:Urb1
|
UTSW |
16 |
90,569,514 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1664:Urb1
|
UTSW |
16 |
90,584,970 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1672:Urb1
|
UTSW |
16 |
90,584,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1694:Urb1
|
UTSW |
16 |
90,563,928 (GRCm39) |
missense |
probably benign |
|
|
R1856:Urb1
|
UTSW |
16 |
90,558,583 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2001:Urb1
|
UTSW |
16 |
90,559,232 (GRCm39) |
missense |
probably benign |
0.30 |
|
R2196:Urb1
|
UTSW |
16 |
90,571,144 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2850:Urb1
|
UTSW |
16 |
90,571,144 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3009:Urb1
|
UTSW |
16 |
90,571,686 (GRCm39) |
missense |
probably benign |
0.09 |
|
R3104:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3105:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3106:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3160:Urb1
|
UTSW |
16 |
90,594,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3162:Urb1
|
UTSW |
16 |
90,594,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3900:Urb1
|
UTSW |
16 |
90,580,264 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4014:Urb1
|
UTSW |
16 |
90,566,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4036:Urb1
|
UTSW |
16 |
90,584,974 (GRCm39) |
missense |
probably benign |
|
|
R4332:Urb1
|
UTSW |
16 |
90,571,425 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4448:Urb1
|
UTSW |
16 |
90,566,282 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4581:Urb1
|
UTSW |
16 |
90,585,034 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4593:Urb1
|
UTSW |
16 |
90,584,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4610:Urb1
|
UTSW |
16 |
90,573,159 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4659:Urb1
|
UTSW |
16 |
90,573,017 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4672:Urb1
|
UTSW |
16 |
90,569,522 (GRCm39) |
missense |
probably benign |
|
|
R4681:Urb1
|
UTSW |
16 |
90,601,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4771:Urb1
|
UTSW |
16 |
90,550,406 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4790:Urb1
|
UTSW |
16 |
90,566,443 (GRCm39) |
nonsense |
probably null |
|
|
R4798:Urb1
|
UTSW |
16 |
90,554,715 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4809:Urb1
|
UTSW |
16 |
90,556,730 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4850:Urb1
|
UTSW |
16 |
90,592,302 (GRCm39) |
nonsense |
probably null |
|
|
R4916:Urb1
|
UTSW |
16 |
90,580,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4969:Urb1
|
UTSW |
16 |
90,602,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Urb1
|
UTSW |
16 |
90,553,059 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5111:Urb1
|
UTSW |
16 |
90,548,905 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5122:Urb1
|
UTSW |
16 |
90,548,983 (GRCm39) |
nonsense |
probably null |
|
|
R5184:Urb1
|
UTSW |
16 |
90,580,162 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5199:Urb1
|
UTSW |
16 |
90,589,636 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5436:Urb1
|
UTSW |
16 |
90,589,650 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5767:Urb1
|
UTSW |
16 |
90,573,051 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5812:Urb1
|
UTSW |
16 |
90,601,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5872:Urb1
|
UTSW |
16 |
90,569,652 (GRCm39) |
nonsense |
probably null |
|
|
R6052:Urb1
|
UTSW |
16 |
90,559,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6063:Urb1
|
UTSW |
16 |
90,585,985 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6065:Urb1
|
UTSW |
16 |
90,600,220 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6181:Urb1
|
UTSW |
16 |
90,575,982 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6268:Urb1
|
UTSW |
16 |
90,550,807 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6429:Urb1
|
UTSW |
16 |
90,559,318 (GRCm39) |
splice site |
probably null |
|
|
R6572:Urb1
|
UTSW |
16 |
90,584,302 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6606:Urb1
|
UTSW |
16 |
90,607,156 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6730:Urb1
|
UTSW |
16 |
90,575,971 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6838:Urb1
|
UTSW |
16 |
90,578,994 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7237:Urb1
|
UTSW |
16 |
90,588,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7339:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7341:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7361:Urb1
|
UTSW |
16 |
90,571,656 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7365:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7366:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7440:Urb1
|
UTSW |
16 |
90,584,296 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7530:Urb1
|
UTSW |
16 |
90,558,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7553:Urb1
|
UTSW |
16 |
90,589,752 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7557:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7603:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7607:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7609:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7610:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7612:Urb1
|
UTSW |
16 |
90,594,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7613:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7684:Urb1
|
UTSW |
16 |
90,583,006 (GRCm39) |
nonsense |
probably null |
|
|
R8029:Urb1
|
UTSW |
16 |
90,576,040 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8324:Urb1
|
UTSW |
16 |
90,588,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8680:Urb1
|
UTSW |
16 |
90,571,513 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8785:Urb1
|
UTSW |
16 |
90,600,311 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8914:Urb1
|
UTSW |
16 |
90,607,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8959:Urb1
|
UTSW |
16 |
90,571,005 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9005:Urb1
|
UTSW |
16 |
90,550,678 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9126:Urb1
|
UTSW |
16 |
90,566,290 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9195:Urb1
|
UTSW |
16 |
90,589,638 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9276:Urb1
|
UTSW |
16 |
90,569,463 (GRCm39) |
splice site |
probably benign |
|
|
R9534:Urb1
|
UTSW |
16 |
90,583,096 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
Z1177:Urb1
|
UTSW |
16 |
90,571,750 (GRCm39) |
missense |
probably benign |
0.05 |
|
Z1177:Urb1
|
UTSW |
16 |
90,550,771 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTGGAAAATAGTTGCATGTATCAG -3'
(R):5'- ATCCATGTGCTCACCTGTGC -3'
Sequencing Primer
(F):5'- ATGTCTGTCTCGGAACCCACTTAAG -3'
(R):5'- CTTACACAGGTTTTGGCAGAGC -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation