Incidental Mutation 'R7250:Myo5c'
| ID |
563849 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myo5c
|
| Ensembl Gene |
ENSMUSG00000033590 |
| Gene Name |
myosin VC |
| Synonyms |
9130003O20Rik |
| MMRRC Submission |
045350-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7250 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
75139302-75212733 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 75169497 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 441
(T441A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000042229
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000036555]
[ENSMUST00000216788]
|
| AlphaFold |
E9Q1F5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000036555
AA Change: T441A
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000042229
Gene: ENSMUSG00000033590
AA Change: T441A
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
61 |
754 |
N/A |
SMART |
|
IQ
|
755 |
777 |
1.11e-3 |
SMART |
|
IQ
|
778 |
800 |
1.39e0 |
SMART |
|
IQ
|
806 |
828 |
8.98e-4 |
SMART |
|
IQ
|
829 |
851 |
4.19e-4 |
SMART |
|
IQ
|
854 |
876 |
2.54e-3 |
SMART |
|
coiled coil region
|
1160 |
1185 |
N/A |
INTRINSIC |
|
coiled coil region
|
1207 |
1245 |
N/A |
INTRINSIC |
|
DIL
|
1574 |
1679 |
5.54e-45 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000216788
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930480E11Rik |
G |
T |
X: 77,414,311 (GRCm39) |
M345I |
probably benign |
Het |
| Actl7b |
T |
A |
4: 56,741,035 (GRCm39) |
M108L |
probably benign |
Het |
| Adgrf3 |
T |
A |
5: 30,400,680 (GRCm39) |
I934L |
probably damaging |
Het |
| Adprm |
A |
G |
11: 66,932,450 (GRCm39) |
V153A |
probably benign |
Het |
| Aif1l |
G |
A |
2: 31,859,764 (GRCm39) |
V109M |
probably damaging |
Het |
| Asphd1 |
T |
A |
7: 126,545,942 (GRCm39) |
E307V |
probably damaging |
Het |
| Ate1 |
T |
A |
7: 130,121,701 (GRCm39) |
|
probably benign |
Het |
| Borcs7 |
A |
G |
19: 46,688,047 (GRCm39) |
H64R |
probably damaging |
Het |
| C1qtnf1 |
A |
G |
11: 118,339,176 (GRCm39) |
*282W |
probably null |
Het |
| Cacna1c |
A |
G |
6: 118,574,966 (GRCm39) |
C1985R |
|
Het |
| Cacna1c |
A |
T |
6: 118,673,412 (GRCm39) |
V647E |
|
Het |
| Cacna1d |
A |
G |
14: 29,797,108 (GRCm39) |
S1497P |
probably damaging |
Het |
| Cacna1e |
T |
A |
1: 154,576,235 (GRCm39) |
I133F |
possibly damaging |
Het |
| Ccdc63 |
A |
T |
5: 122,260,906 (GRCm39) |
L206H |
probably damaging |
Het |
| Cenatac |
A |
G |
9: 44,323,748 (GRCm39) |
|
probably null |
Het |
| Cspg4b |
T |
G |
13: 113,455,349 (GRCm39) |
I465R |
|
Het |
| D430041D05Rik |
T |
C |
2: 104,086,961 (GRCm39) |
T672A |
possibly damaging |
Het |
| D630045J12Rik |
G |
T |
6: 38,119,546 (GRCm39) |
T1732K |
possibly damaging |
Het |
| D930020B18Rik |
T |
C |
10: 121,507,736 (GRCm39) |
I158T |
probably damaging |
Het |
| Ddx52 |
G |
A |
11: 83,835,392 (GRCm39) |
G106D |
probably benign |
Het |
| Dock2 |
A |
G |
11: 34,586,032 (GRCm39) |
V550A |
probably benign |
Het |
| Dock2 |
C |
T |
11: 34,586,120 (GRCm39) |
D521N |
probably damaging |
Het |
| F13b |
T |
C |
1: 139,444,227 (GRCm39) |
|
probably null |
Het |
| Fchsd2 |
A |
G |
7: 100,908,892 (GRCm39) |
K431R |
possibly damaging |
Het |
| Fez1 |
C |
T |
9: 36,779,090 (GRCm39) |
R256C |
probably damaging |
Het |
| Gjd4 |
T |
A |
18: 9,280,391 (GRCm39) |
Q229L |
probably benign |
Het |
| Gpr45 |
T |
A |
1: 43,071,531 (GRCm39) |
I58N |
probably damaging |
Het |
| Gstm1 |
T |
A |
3: 107,923,709 (GRCm39) |
I99F |
probably damaging |
Het |
| Gtpbp8 |
T |
A |
16: 44,564,225 (GRCm39) |
T149S |
probably damaging |
Het |
| H2-Ab1 |
A |
G |
17: 34,486,481 (GRCm39) |
D180G |
probably damaging |
Het |
| Hdhd5 |
A |
G |
6: 120,494,016 (GRCm39) |
I188T |
possibly damaging |
Het |
| Hfm1 |
T |
C |
5: 107,052,197 (GRCm39) |
I300V |
probably benign |
Het |
| Hnrnpr |
T |
G |
4: 136,059,746 (GRCm39) |
D283E |
probably benign |
Het |
| Hsp90b1 |
T |
C |
10: 86,527,572 (GRCm39) |
E768G |
unknown |
Het |
| Kcna4 |
C |
A |
2: 107,126,663 (GRCm39) |
Q466K |
possibly damaging |
Het |
| Kcnk6 |
A |
G |
7: 28,931,619 (GRCm39) |
L97P |
probably benign |
Het |
| Kics2 |
T |
C |
10: 121,581,376 (GRCm39) |
S126P |
possibly damaging |
Het |
| Klf5 |
A |
G |
14: 99,536,455 (GRCm39) |
S9G |
probably benign |
Het |
| Kmt2c |
C |
A |
5: 25,504,489 (GRCm39) |
K3606N |
probably damaging |
Het |
| Kmt2c |
T |
C |
5: 25,514,805 (GRCm39) |
T3013A |
probably benign |
Het |
| Lancl1 |
A |
G |
1: 67,048,458 (GRCm39) |
Y207H |
possibly damaging |
Het |
| Lipe |
G |
C |
7: 25,088,085 (GRCm39) |
|
probably benign |
Het |
| Lrrc66 |
T |
A |
5: 73,768,224 (GRCm39) |
H239L |
probably benign |
Het |
| Ltbp2 |
C |
T |
12: 84,834,166 (GRCm39) |
W1441* |
probably null |
Het |
| Man2a1 |
T |
C |
17: 64,943,583 (GRCm39) |
S213P |
probably benign |
Het |
| Mapre2 |
C |
T |
18: 23,991,119 (GRCm39) |
A171V |
possibly damaging |
Het |
| Mdn1 |
T |
A |
4: 32,695,427 (GRCm39) |
D1155E |
probably damaging |
Het |
| Mki67 |
T |
C |
7: 135,301,053 (GRCm39) |
D1327G |
possibly damaging |
Het |
| Mx2 |
T |
C |
16: 97,348,664 (GRCm39) |
I279T |
probably damaging |
Het |
| Nlrp9a |
T |
G |
7: 26,258,143 (GRCm39) |
V587G |
possibly damaging |
Het |
| Npas2 |
A |
T |
1: 39,377,188 (GRCm39) |
T517S |
probably damaging |
Het |
| Npy1r |
T |
C |
8: 67,157,712 (GRCm39) |
S341P |
probably benign |
Het |
| Ntm |
A |
G |
9: 29,322,988 (GRCm39) |
W11R |
probably benign |
Het |
| Nxpe2 |
A |
T |
9: 48,238,096 (GRCm39) |
I53N |
possibly damaging |
Het |
| Onecut2 |
T |
C |
18: 64,519,511 (GRCm39) |
F443L |
probably benign |
Het |
| Or10g6 |
T |
A |
9: 39,934,050 (GRCm39) |
Y120* |
probably null |
Het |
| Or2r2 |
A |
G |
6: 42,463,689 (GRCm39) |
V146A |
probably benign |
Het |
| Or52ac1 |
A |
T |
7: 104,245,738 (GRCm39) |
Y217N |
probably damaging |
Het |
| Parp2 |
T |
A |
14: 51,054,801 (GRCm39) |
V248E |
probably benign |
Het |
| Pcdh12 |
C |
A |
18: 38,415,029 (GRCm39) |
V699L |
probably benign |
Het |
| Pja2 |
G |
A |
17: 64,616,451 (GRCm39) |
P148L |
probably benign |
Het |
| Poglut3 |
C |
T |
9: 53,301,821 (GRCm39) |
Q158* |
probably null |
Het |
| Ppip5k2 |
T |
G |
1: 97,673,187 (GRCm39) |
D415A |
probably benign |
Het |
| Prss47 |
A |
G |
13: 65,200,355 (GRCm39) |
S74P |
probably benign |
Het |
| Ptprg |
G |
T |
14: 12,166,767 (GRCm38) |
M723I |
probably benign |
Het |
| Qsox2 |
A |
T |
2: 26,118,444 (GRCm39) |
I109N |
probably damaging |
Het |
| Ranbp3l |
A |
G |
15: 9,041,853 (GRCm39) |
E217G |
probably benign |
Het |
| Rgl2 |
C |
T |
17: 34,152,403 (GRCm39) |
R367W |
probably damaging |
Het |
| Rgs12 |
T |
A |
5: 35,122,841 (GRCm39) |
F208Y |
probably damaging |
Het |
| Rin3 |
C |
T |
12: 102,334,893 (GRCm39) |
T268I |
unknown |
Het |
| Rttn |
T |
A |
18: 89,007,647 (GRCm39) |
D427E |
probably benign |
Het |
| Samd13 |
G |
A |
3: 146,352,079 (GRCm39) |
P91S |
probably benign |
Het |
| Samd9l |
T |
C |
6: 3,374,201 (GRCm39) |
D1020G |
possibly damaging |
Het |
| Sec62 |
T |
G |
3: 30,866,496 (GRCm39) |
L201V |
possibly damaging |
Het |
| Setdb1 |
C |
T |
3: 95,261,852 (GRCm39) |
|
probably null |
Het |
| Sf3a3 |
A |
T |
4: 124,616,708 (GRCm39) |
T197S |
probably benign |
Het |
| Slc20a1 |
A |
T |
2: 129,051,844 (GRCm39) |
I618F |
possibly damaging |
Het |
| Slc38a3 |
A |
T |
9: 107,533,865 (GRCm39) |
M186K |
probably benign |
Het |
| Slc39a13 |
T |
C |
2: 90,893,503 (GRCm39) |
T319A |
probably benign |
Het |
| Slc44a4 |
T |
C |
17: 35,137,520 (GRCm39) |
|
probably null |
Het |
| St3gal1 |
A |
C |
15: 66,978,578 (GRCm39) |
D314E |
possibly damaging |
Het |
| Suclg1 |
A |
G |
6: 73,248,074 (GRCm39) |
N265S |
probably benign |
Het |
| Sult2b1 |
A |
T |
7: 45,433,361 (GRCm39) |
V2D |
unknown |
Het |
| Supv3l1 |
T |
A |
10: 62,280,846 (GRCm39) |
I182F |
probably damaging |
Het |
| Tcp11l2 |
T |
C |
10: 84,423,105 (GRCm39) |
|
probably null |
Het |
| Tenm2 |
C |
A |
11: 35,963,625 (GRCm39) |
L935F |
probably damaging |
Het |
| Tnks |
T |
A |
8: 35,318,912 (GRCm39) |
I790F |
probably damaging |
Het |
| Top2b |
C |
T |
14: 16,420,411 (GRCm38) |
T1274I |
probably benign |
Het |
| Tpi1 |
A |
T |
6: 124,789,441 (GRCm39) |
I178N |
probably damaging |
Het |
| Trav9d-1 |
A |
T |
14: 53,030,153 (GRCm39) |
S86C |
probably damaging |
Het |
| Treml2 |
A |
G |
17: 48,616,155 (GRCm39) |
E265G |
probably benign |
Het |
| Trpm7 |
A |
T |
2: 126,668,685 (GRCm39) |
S744T |
possibly damaging |
Het |
| Usp33 |
T |
A |
3: 152,097,999 (GRCm39) |
L909* |
probably null |
Het |
| Vcan |
A |
G |
13: 89,869,805 (GRCm39) |
I210T |
probably damaging |
Het |
| Vcan |
A |
T |
13: 89,879,576 (GRCm39) |
|
probably null |
Het |
| Vsig10l |
A |
T |
7: 43,113,099 (GRCm39) |
D17V |
probably benign |
Het |
| Zbtb7b |
T |
A |
3: 89,286,976 (GRCm39) |
T498S |
probably benign |
Het |
| Zfp366 |
T |
A |
13: 99,366,076 (GRCm39) |
H412Q |
probably damaging |
Het |
| Zfp53 |
C |
A |
17: 21,729,840 (GRCm39) |
D624E |
probably damaging |
Het |
| Zfp827 |
A |
T |
8: 79,916,721 (GRCm39) |
D432V |
|
Het |
| Zic1 |
T |
C |
9: 91,247,028 (GRCm39) |
T15A |
probably damaging |
Het |
| Zswim8 |
T |
C |
14: 20,770,036 (GRCm39) |
C1368R |
probably damaging |
Het |
|
| Other mutations in Myo5c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00093:Myo5c
|
APN |
9 |
75,150,162 (GRCm39) |
splice site |
probably benign |
|
|
IGL00848:Myo5c
|
APN |
9 |
75,196,463 (GRCm39) |
missense |
probably benign |
|
|
IGL01503:Myo5c
|
APN |
9 |
75,170,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01735:Myo5c
|
APN |
9 |
75,208,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01866:Myo5c
|
APN |
9 |
75,176,864 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01956:Myo5c
|
APN |
9 |
75,150,158 (GRCm39) |
splice site |
probably null |
|
|
IGL02127:Myo5c
|
APN |
9 |
75,208,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02268:Myo5c
|
APN |
9 |
75,153,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02272:Myo5c
|
APN |
9 |
75,173,442 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL03052:Myo5c
|
APN |
9 |
75,159,798 (GRCm39) |
splice site |
probably benign |
|
|
IGL03179:Myo5c
|
APN |
9 |
75,163,148 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL03224:Myo5c
|
APN |
9 |
75,185,525 (GRCm39) |
missense |
probably benign |
0.01 |
|
Marked
|
UTSW |
9 |
75,182,919 (GRCm39) |
critical splice donor site |
probably null |
|
|
pixie
|
UTSW |
9 |
75,193,860 (GRCm39) |
missense |
probably benign |
0.26 |
|
PIT4142001:Myo5c
|
UTSW |
9 |
75,191,230 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4431001:Myo5c
|
UTSW |
9 |
75,159,853 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R0126:Myo5c
|
UTSW |
9 |
75,176,807 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0266:Myo5c
|
UTSW |
9 |
75,191,498 (GRCm39) |
splice site |
probably benign |
|
|
R0345:Myo5c
|
UTSW |
9 |
75,204,701 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0387:Myo5c
|
UTSW |
9 |
75,192,303 (GRCm39) |
splice site |
probably benign |
|
|
R0602:Myo5c
|
UTSW |
9 |
75,173,478 (GRCm39) |
splice site |
probably null |
|
|
R0675:Myo5c
|
UTSW |
9 |
75,185,571 (GRCm39) |
missense |
probably benign |
|
|
R0798:Myo5c
|
UTSW |
9 |
75,165,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0981:Myo5c
|
UTSW |
9 |
75,178,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1051:Myo5c
|
UTSW |
9 |
75,198,165 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1072:Myo5c
|
UTSW |
9 |
75,199,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1144:Myo5c
|
UTSW |
9 |
75,193,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1454:Myo5c
|
UTSW |
9 |
75,170,348 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1476:Myo5c
|
UTSW |
9 |
75,183,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1484:Myo5c
|
UTSW |
9 |
75,208,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1586:Myo5c
|
UTSW |
9 |
75,174,313 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1616:Myo5c
|
UTSW |
9 |
75,203,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Myo5c
|
UTSW |
9 |
75,184,357 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1800:Myo5c
|
UTSW |
9 |
75,153,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1838:Myo5c
|
UTSW |
9 |
75,180,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1840:Myo5c
|
UTSW |
9 |
75,157,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1885:Myo5c
|
UTSW |
9 |
75,157,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1897:Myo5c
|
UTSW |
9 |
75,199,523 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1898:Myo5c
|
UTSW |
9 |
75,204,908 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2029:Myo5c
|
UTSW |
9 |
75,196,337 (GRCm39) |
unclassified |
probably benign |
|
|
R2063:Myo5c
|
UTSW |
9 |
75,189,150 (GRCm39) |
missense |
probably benign |
0.19 |
|
R2230:Myo5c
|
UTSW |
9 |
75,180,888 (GRCm39) |
missense |
probably benign |
|
|
R2519:Myo5c
|
UTSW |
9 |
75,157,718 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2520:Myo5c
|
UTSW |
9 |
75,204,931 (GRCm39) |
nonsense |
probably null |
|
|
R3034:Myo5c
|
UTSW |
9 |
75,193,859 (GRCm39) |
missense |
probably benign |
0.44 |
|
R3117:Myo5c
|
UTSW |
9 |
75,173,476 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3432:Myo5c
|
UTSW |
9 |
75,170,283 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3751:Myo5c
|
UTSW |
9 |
75,183,284 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4132:Myo5c
|
UTSW |
9 |
75,159,850 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4173:Myo5c
|
UTSW |
9 |
75,153,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4239:Myo5c
|
UTSW |
9 |
75,191,224 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4429:Myo5c
|
UTSW |
9 |
75,201,283 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4574:Myo5c
|
UTSW |
9 |
75,176,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4791:Myo5c
|
UTSW |
9 |
75,198,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4804:Myo5c
|
UTSW |
9 |
75,152,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4819:Myo5c
|
UTSW |
9 |
75,199,484 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4881:Myo5c
|
UTSW |
9 |
75,191,434 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4900:Myo5c
|
UTSW |
9 |
75,180,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4964:Myo5c
|
UTSW |
9 |
75,204,791 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4966:Myo5c
|
UTSW |
9 |
75,176,878 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5057:Myo5c
|
UTSW |
9 |
75,208,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5347:Myo5c
|
UTSW |
9 |
75,202,487 (GRCm39) |
missense |
probably null |
1.00 |
|
R5399:Myo5c
|
UTSW |
9 |
75,195,356 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5440:Myo5c
|
UTSW |
9 |
75,165,407 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5569:Myo5c
|
UTSW |
9 |
75,180,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5600:Myo5c
|
UTSW |
9 |
75,196,436 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5606:Myo5c
|
UTSW |
9 |
75,182,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5704:Myo5c
|
UTSW |
9 |
75,180,185 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5798:Myo5c
|
UTSW |
9 |
75,191,480 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5865:Myo5c
|
UTSW |
9 |
75,204,770 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6034:Myo5c
|
UTSW |
9 |
75,163,187 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6034:Myo5c
|
UTSW |
9 |
75,163,187 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6143:Myo5c
|
UTSW |
9 |
75,157,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6242:Myo5c
|
UTSW |
9 |
75,180,893 (GRCm39) |
missense |
probably benign |
|
|
R6253:Myo5c
|
UTSW |
9 |
75,152,319 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6264:Myo5c
|
UTSW |
9 |
75,182,836 (GRCm39) |
missense |
probably benign |
|
|
R6307:Myo5c
|
UTSW |
9 |
75,180,198 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R6358:Myo5c
|
UTSW |
9 |
75,203,294 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6450:Myo5c
|
UTSW |
9 |
75,193,860 (GRCm39) |
missense |
probably benign |
0.26 |
|
R6598:Myo5c
|
UTSW |
9 |
75,153,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6618:Myo5c
|
UTSW |
9 |
75,182,919 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6774:Myo5c
|
UTSW |
9 |
75,196,468 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6865:Myo5c
|
UTSW |
9 |
75,176,878 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6996:Myo5c
|
UTSW |
9 |
75,157,746 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7023:Myo5c
|
UTSW |
9 |
75,208,738 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7123:Myo5c
|
UTSW |
9 |
75,196,505 (GRCm39) |
missense |
probably benign |
|
|
R7316:Myo5c
|
UTSW |
9 |
75,176,920 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7340:Myo5c
|
UTSW |
9 |
75,196,423 (GRCm39) |
missense |
probably benign |
|
|
R7382:Myo5c
|
UTSW |
9 |
75,211,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7426:Myo5c
|
UTSW |
9 |
75,158,809 (GRCm39) |
splice site |
probably null |
|
|
R7788:Myo5c
|
UTSW |
9 |
75,186,627 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7956:Myo5c
|
UTSW |
9 |
75,159,845 (GRCm39) |
missense |
probably benign |
|
|
R8082:Myo5c
|
UTSW |
9 |
75,182,793 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8290:Myo5c
|
UTSW |
9 |
75,196,178 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8406:Myo5c
|
UTSW |
9 |
75,182,823 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8481:Myo5c
|
UTSW |
9 |
75,208,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8489:Myo5c
|
UTSW |
9 |
75,180,128 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8505:Myo5c
|
UTSW |
9 |
75,153,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8685:Myo5c
|
UTSW |
9 |
75,192,229 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R8806:Myo5c
|
UTSW |
9 |
75,150,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8871:Myo5c
|
UTSW |
9 |
75,185,585 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9323:Myo5c
|
UTSW |
9 |
75,153,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9484:Myo5c
|
UTSW |
9 |
75,204,770 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9639:Myo5c
|
UTSW |
9 |
75,165,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Myo5c
|
UTSW |
9 |
75,152,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Myo5c
|
UTSW |
9 |
75,153,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGACTGCCAGCTTAGAAGGAAC -3'
(R):5'- CAGGCATGCTTGGATTCCTG -3'
Sequencing Primer
(F):5'- GCTTTGAAGTAGTTTAAACTTGCCG -3'
(R):5'- CATGCTTGGATTCCTGAATGAG -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation