Incidental Mutation 'R7260:Mical2'
| ID |
564537 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mical2
|
| Ensembl Gene |
ENSMUSG00000038244 |
| Gene Name |
microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| Synonyms |
4921517J23Rik, Ebitein1, 5330438E18Rik, Micalcl |
| MMRRC Submission |
045352-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.242)
|
| Stock # |
R7260 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
111825063-112012313 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 111919001 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Leucine
at position 430
(Q430L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000047639
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037991]
[ENSMUST00000050149]
|
| AlphaFold |
Q8BML1
Q9D5U9 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000037991
AA Change: Q430L
PolyPhen 2
Score 0.102 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000047639
Gene: ENSMUSG00000038244
AA Change: Q430L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
1e-8 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
3.2e-6 |
PFAM |
|
low complexity region
|
175 |
188 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
low complexity region
|
894 |
925 |
N/A |
INTRINSIC |
|
LIM
|
979 |
1033 |
9.91e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000050149
AA Change: Q430L
PolyPhen 2
Score 0.015 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000051163
Gene: ENSMUSG00000038244
AA Change: Q430L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
1.1e-8 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
1.5e-6 |
PFAM |
|
Pfam:Pyr_redox_2
|
88 |
259 |
1.3e-6 |
PFAM |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
LIM
|
752 |
806 |
9.91e-10 |
SMART |
|
low complexity region
|
918 |
926 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
98% (78/80) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310057J18Rik |
A |
G |
10: 28,849,882 (GRCm39) |
S293P |
probably benign |
Het |
| Actn2 |
T |
C |
13: 12,291,376 (GRCm39) |
N676S |
probably benign |
Het |
| Amfr |
C |
T |
8: 94,702,776 (GRCm39) |
M463I |
possibly damaging |
Het |
| Ankdd1a |
G |
T |
9: 65,411,834 (GRCm39) |
A325D |
probably damaging |
Het |
| Apba2 |
A |
G |
7: 64,389,493 (GRCm39) |
D463G |
probably damaging |
Het |
| Arid5b |
A |
G |
10: 67,933,637 (GRCm39) |
V755A |
probably damaging |
Het |
| Boc |
A |
T |
16: 44,310,533 (GRCm39) |
F796I |
|
Het |
| Ccnt1 |
G |
A |
15: 98,463,005 (GRCm39) |
Q56* |
probably null |
Het |
| Cd248 |
T |
A |
19: 5,119,383 (GRCm39) |
Y410* |
probably null |
Het |
| Chd9 |
T |
A |
8: 91,721,171 (GRCm39) |
N986K |
unknown |
Het |
| Col6a6 |
T |
C |
9: 105,661,168 (GRCm39) |
T314A |
probably benign |
Het |
| Cpped1 |
A |
G |
16: 11,646,327 (GRCm39) |
F142L |
possibly damaging |
Het |
| Csmd1 |
C |
T |
8: 16,050,574 (GRCm39) |
A2221T |
probably damaging |
Het |
| Cyp2c69 |
C |
A |
19: 39,831,344 (GRCm39) |
V490L |
probably benign |
Het |
| Cyrib |
A |
T |
15: 63,829,438 (GRCm39) |
F23L |
possibly damaging |
Het |
| Dcst2 |
T |
C |
3: 89,273,593 (GRCm39) |
F157S |
probably damaging |
Het |
| Ddx54 |
G |
T |
5: 120,764,985 (GRCm39) |
R788L |
probably benign |
Het |
| Dnah1 |
T |
C |
14: 30,991,343 (GRCm39) |
Y3145C |
probably damaging |
Het |
| Dnah14 |
A |
T |
1: 181,534,309 (GRCm39) |
R2320W |
probably damaging |
Het |
| Dnai3 |
T |
A |
3: 145,752,295 (GRCm39) |
M794L |
probably benign |
Het |
| Emilin2 |
T |
C |
17: 71,581,785 (GRCm39) |
T314A |
probably benign |
Het |
| Eml2 |
A |
G |
7: 18,934,515 (GRCm39) |
S405G |
probably benign |
Het |
| Ephb2 |
A |
G |
4: 136,498,885 (GRCm39) |
F65L |
probably damaging |
Het |
| Fbn2 |
T |
C |
18: 58,199,188 (GRCm39) |
D1360G |
probably benign |
Het |
| Fbxo22 |
A |
G |
9: 55,125,754 (GRCm39) |
T206A |
probably benign |
Het |
| Filip1l |
A |
G |
16: 57,391,287 (GRCm39) |
E625G |
probably damaging |
Het |
| Gen1 |
A |
C |
12: 11,306,849 (GRCm39) |
M172R |
probably damaging |
Het |
| Gk5 |
A |
G |
9: 96,001,663 (GRCm39) |
K54E |
probably benign |
Het |
| Glis3 |
T |
C |
19: 28,508,802 (GRCm39) |
E394G |
probably benign |
Het |
| Helq |
T |
A |
5: 100,939,793 (GRCm39) |
E373D |
probably damaging |
Het |
| Ighv1-74 |
A |
G |
12: 115,766,372 (GRCm39) |
F83L |
probably benign |
Het |
| Ints15 |
A |
G |
5: 143,297,594 (GRCm39) |
V151A |
probably benign |
Het |
| Iqcn |
T |
C |
8: 71,161,397 (GRCm39) |
Y197H |
probably benign |
Het |
| Kdm4d |
T |
C |
9: 14,374,454 (GRCm39) |
D468G |
probably benign |
Het |
| Kif20b |
A |
G |
19: 34,927,610 (GRCm39) |
I957M |
probably damaging |
Het |
| Ldhal6b |
A |
G |
17: 5,468,535 (GRCm39) |
F133S |
possibly damaging |
Het |
| Loxhd1 |
T |
C |
18: 77,420,338 (GRCm39) |
Y321H |
possibly damaging |
Het |
| Ltbp1 |
A |
T |
17: 75,373,139 (GRCm39) |
M261L |
probably benign |
Het |
| Mroh4 |
A |
T |
15: 74,479,978 (GRCm39) |
N885K |
possibly damaging |
Het |
| Ms4a7 |
A |
G |
19: 11,299,710 (GRCm39) |
Y231H |
probably damaging |
Het |
| Msh2 |
G |
T |
17: 88,025,047 (GRCm39) |
V642F |
probably damaging |
Het |
| Muc5b |
G |
T |
7: 141,396,385 (GRCm39) |
A166S |
unknown |
Het |
| Myo18b |
T |
C |
5: 112,923,154 (GRCm39) |
I1868V |
probably benign |
Het |
| Nfatc3 |
T |
C |
8: 106,835,578 (GRCm39) |
S975P |
probably benign |
Het |
| Oacyl |
T |
C |
18: 65,831,438 (GRCm39) |
L25P |
probably damaging |
Het |
| Or12e10 |
A |
G |
2: 87,640,731 (GRCm39) |
N189S |
probably damaging |
Het |
| Or5b109 |
T |
C |
19: 13,212,388 (GRCm39) |
F258S |
probably damaging |
Het |
| Or5w15 |
T |
C |
2: 87,568,852 (GRCm39) |
|
probably null |
Het |
| Or6c69 |
T |
A |
10: 129,748,156 (GRCm39) |
|
probably benign |
Het |
| Or8a1 |
T |
A |
9: 37,642,049 (GRCm39) |
I77F |
probably damaging |
Het |
| Patj |
A |
G |
4: 98,304,970 (GRCm39) |
I275V |
possibly damaging |
Het |
| Pdcd11 |
G |
A |
19: 47,117,673 (GRCm39) |
R1674Q |
possibly damaging |
Het |
| Peg10 |
CCACATCAGGATCCACATCAGGATGCACATCAGCATCAGGATCCCCATCAGGATGCACATCAGGATCCACATCAGGATGCACATCAG |
CCACATCAGGATCCACATCAGGATGCACATCAG |
6: 4,756,398 (GRCm39) |
|
probably benign |
Het |
| Phkb |
T |
A |
8: 86,604,759 (GRCm39) |
Y55N |
probably benign |
Het |
| Pias4 |
A |
G |
10: 80,993,302 (GRCm39) |
V207A |
possibly damaging |
Het |
| Plxna4 |
C |
A |
6: 32,216,455 (GRCm39) |
R540L |
possibly damaging |
Het |
| Psapl1 |
G |
A |
5: 36,362,556 (GRCm39) |
V383M |
probably benign |
Het |
| Rars1 |
C |
A |
11: 35,725,281 (GRCm39) |
A10S |
probably benign |
Het |
| Rhobtb1 |
A |
T |
10: 69,106,610 (GRCm39) |
K454* |
probably null |
Het |
| Rmnd1 |
A |
T |
10: 4,364,803 (GRCm39) |
|
probably null |
Het |
| Rnf213 |
A |
G |
11: 119,343,401 (GRCm39) |
I3589V |
|
Het |
| Rngtt |
T |
C |
4: 33,356,176 (GRCm39) |
S338P |
possibly damaging |
Het |
| Sh3bgr |
A |
G |
16: 96,025,681 (GRCm39) |
E189G |
unknown |
Het |
| Slc30a3 |
G |
A |
5: 31,245,690 (GRCm39) |
T281I |
probably damaging |
Het |
| Smok3c |
T |
A |
5: 138,063,885 (GRCm39) |
D457E |
possibly damaging |
Het |
| Stard9 |
C |
A |
2: 120,537,419 (GRCm39) |
Q4274K |
possibly damaging |
Het |
| Syne2 |
G |
T |
12: 75,991,853 (GRCm39) |
L1938F |
probably damaging |
Het |
| Tmem70 |
C |
A |
1: 16,735,590 (GRCm39) |
T20K |
possibly damaging |
Het |
| Tnrc6a |
A |
G |
7: 122,785,813 (GRCm39) |
E1502G |
probably benign |
Het |
| Tpp1 |
A |
T |
7: 105,396,704 (GRCm39) |
S438T |
probably benign |
Het |
| Tubb2a |
T |
A |
13: 34,259,397 (GRCm39) |
Q131L |
probably damaging |
Het |
| Ube2v1 |
A |
G |
2: 167,471,114 (GRCm39) |
S26P |
probably benign |
Het |
| Unc13a |
G |
T |
8: 72,113,229 (GRCm39) |
S207R |
possibly damaging |
Het |
| Usp35 |
T |
G |
7: 96,969,286 (GRCm39) |
D362A |
probably damaging |
Het |
| Utp20 |
A |
G |
10: 88,587,334 (GRCm39) |
I2487T |
probably benign |
Het |
| Vmn2r111 |
T |
C |
17: 22,778,032 (GRCm39) |
N549S |
possibly damaging |
Het |
| Vmn2r117 |
T |
A |
17: 23,694,359 (GRCm39) |
H496L |
probably benign |
Het |
| Vmn2r92 |
C |
T |
17: 18,387,138 (GRCm39) |
A159V |
probably damaging |
Het |
| Wiz |
T |
C |
17: 32,578,085 (GRCm39) |
K467E |
probably damaging |
Het |
| Zfp534 |
T |
C |
4: 147,759,461 (GRCm39) |
T403A |
probably benign |
Het |
| Zswim5 |
T |
C |
4: 116,819,843 (GRCm39) |
L416P |
probably damaging |
Het |
|
| Other mutations in Mical2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Mical2
|
APN |
7 |
111,981,352 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00886:Mical2
|
APN |
7 |
111,914,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00934:Mical2
|
APN |
7 |
111,948,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00941:Mical2
|
APN |
7 |
111,920,652 (GRCm39) |
splice site |
probably benign |
|
|
IGL01020:Mical2
|
APN |
7 |
111,914,283 (GRCm39) |
splice site |
probably benign |
|
|
IGL01395:Mical2
|
APN |
7 |
111,922,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01658:Mical2
|
APN |
7 |
111,914,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01775:Mical2
|
APN |
7 |
111,981,269 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02040:Mical2
|
APN |
7 |
111,910,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02051:Mical2
|
APN |
7 |
111,980,597 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02388:Mical2
|
APN |
7 |
111,934,620 (GRCm39) |
missense |
probably benign |
|
|
IGL02551:Mical2
|
APN |
7 |
111,923,197 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02578:Mical2
|
APN |
7 |
111,950,580 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02751:Mical2
|
APN |
7 |
111,931,243 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL03114:Mical2
|
APN |
7 |
111,996,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0091:Mical2
|
UTSW |
7 |
111,980,503 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0101:Mical2
|
UTSW |
7 |
111,936,074 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0415:Mical2
|
UTSW |
7 |
111,980,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0504:Mical2
|
UTSW |
7 |
111,870,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0594:Mical2
|
UTSW |
7 |
111,917,657 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0609:Mical2
|
UTSW |
7 |
111,920,647 (GRCm39) |
splice site |
probably null |
|
|
R0962:Mical2
|
UTSW |
7 |
111,979,624 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1521:Mical2
|
UTSW |
7 |
111,980,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1542:Mical2
|
UTSW |
7 |
111,908,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1611:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1740:Mical2
|
UTSW |
7 |
111,933,043 (GRCm39) |
missense |
probably benign |
|
|
R1815:Mical2
|
UTSW |
7 |
112,012,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1855:Mical2
|
UTSW |
7 |
111,944,489 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1958:Mical2
|
UTSW |
7 |
111,980,311 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1962:Mical2
|
UTSW |
7 |
112,012,051 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2086:Mical2
|
UTSW |
7 |
111,917,810 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2136:Mical2
|
UTSW |
7 |
111,870,722 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2418:Mical2
|
UTSW |
7 |
111,919,941 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2439:Mical2
|
UTSW |
7 |
111,994,002 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3053:Mical2
|
UTSW |
7 |
111,910,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3979:Mical2
|
UTSW |
7 |
112,006,885 (GRCm39) |
splice site |
probably null |
|
|
R4308:Mical2
|
UTSW |
7 |
111,931,199 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4551:Mical2
|
UTSW |
7 |
111,981,123 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4583:Mical2
|
UTSW |
7 |
112,012,154 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4663:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4868:Mical2
|
UTSW |
7 |
111,917,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Mical2
|
UTSW |
7 |
111,936,107 (GRCm39) |
missense |
probably benign |
|
|
R5112:Mical2
|
UTSW |
7 |
111,919,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5459:Mical2
|
UTSW |
7 |
111,981,444 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5487:Mical2
|
UTSW |
7 |
111,919,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5563:Mical2
|
UTSW |
7 |
111,914,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5763:Mical2
|
UTSW |
7 |
111,973,861 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5817:Mical2
|
UTSW |
7 |
111,922,866 (GRCm39) |
missense |
probably benign |
|
|
R5987:Mical2
|
UTSW |
7 |
111,934,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6042:Mical2
|
UTSW |
7 |
111,979,619 (GRCm39) |
missense |
probably benign |
0.40 |
|
R6087:Mical2
|
UTSW |
7 |
111,917,692 (GRCm39) |
nonsense |
probably null |
|
|
R6189:Mical2
|
UTSW |
7 |
112,012,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Mical2
|
UTSW |
7 |
111,923,293 (GRCm39) |
splice site |
probably null |
|
|
R6311:Mical2
|
UTSW |
7 |
111,922,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6319:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6578:Mical2
|
UTSW |
7 |
111,910,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6750:Mical2
|
UTSW |
7 |
111,981,046 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6782:Mical2
|
UTSW |
7 |
111,945,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6798:Mical2
|
UTSW |
7 |
111,975,266 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R7061:Mical2
|
UTSW |
7 |
111,946,008 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7147:Mical2
|
UTSW |
7 |
111,922,810 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7266:Mical2
|
UTSW |
7 |
111,902,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7347:Mical2
|
UTSW |
7 |
111,981,358 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7391:Mical2
|
UTSW |
7 |
111,919,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7747:Mical2
|
UTSW |
7 |
111,933,046 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7783:Mical2
|
UTSW |
7 |
112,012,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7818:Mical2
|
UTSW |
7 |
111,944,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7824:Mical2
|
UTSW |
7 |
112,006,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Mical2
|
UTSW |
7 |
111,980,975 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8022:Mical2
|
UTSW |
7 |
111,902,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Mical2
|
UTSW |
7 |
111,944,460 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8505:Mical2
|
UTSW |
7 |
111,919,007 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8532:Mical2
|
UTSW |
7 |
111,917,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8830:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8862:Mical2
|
UTSW |
7 |
111,910,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8988:Mical2
|
UTSW |
7 |
111,910,661 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9006:Mical2
|
UTSW |
7 |
111,981,323 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9123:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9127:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9128:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9129:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9140:Mical2
|
UTSW |
7 |
112,006,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9187:Mical2
|
UTSW |
7 |
111,902,797 (GRCm39) |
nonsense |
probably null |
|
|
R9233:Mical2
|
UTSW |
7 |
111,981,399 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9304:Mical2
|
UTSW |
7 |
111,980,974 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9310:Mical2
|
UTSW |
7 |
111,950,920 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9377:Mical2
|
UTSW |
7 |
111,981,246 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9399:Mical2
|
UTSW |
7 |
111,946,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Mical2
|
UTSW |
7 |
112,010,665 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9500:Mical2
|
UTSW |
7 |
111,936,054 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9620:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9652:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Mical2
|
UTSW |
7 |
111,921,806 (GRCm39) |
missense |
probably benign |
0.37 |
|
R9756:Mical2
|
UTSW |
7 |
111,902,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9789:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF008:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0062:Mical2
|
UTSW |
7 |
111,946,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTTCAGAGCTGGCAGTCAG -3'
(R):5'- TTCGACTATCCAGGGCACAG -3'
Sequencing Primer
(F):5'- CAGTGCTGGATAGAATGG -3'
(R):5'- TATCCAGGGCACAGAGAAACTC -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation