Incidental Mutation 'R7282:Carmil1'
| ID |
565757 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Carmil1
|
| Ensembl Gene |
ENSMUSG00000021338 |
| Gene Name |
capping protein regulator and myosin 1 linker 1 |
| Synonyms |
Carmil, Lrrc16a, 1110037D04Rik, Lrrc16 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7282 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
24196327-24464778 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 24197387 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 1350
(S1350P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000072662
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072889]
[ENSMUST00000110398]
[ENSMUST00000125901]
|
| AlphaFold |
Q6EDY6 |
| PDB Structure |
Solution structure of the CARMIL CAH3a/b domain bound to capping protein (CP) [SOLUTION NMR]
Crystal structure of Actin Capping Protein in complex with the Cp-binding motif derived from CARMIL [X-RAY DIFFRACTION]
Crystal structure of Actin capping protein in complex with CARMIL fragment [X-RAY DIFFRACTION]
Crystal Structure of mouse CARMIL residues 1-668 [X-RAY DIFFRACTION]
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000072889
AA Change: S1350P
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000072662
Gene: ENSMUSG00000021338
AA Change: S1350P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
37 |
N/A |
INTRINSIC |
|
LRR
|
245 |
272 |
2.42e1 |
SMART |
|
LRR
|
275 |
302 |
1.04e1 |
SMART |
|
LRR
|
304 |
331 |
3.1e0 |
SMART |
|
LRR
|
336 |
363 |
5.66e1 |
SMART |
|
Blast:LRR
|
423 |
450 |
9e-8 |
BLAST |
|
Blast:LRR
|
451 |
484 |
7e-9 |
BLAST |
|
LRR
|
574 |
601 |
8.81e-2 |
SMART |
|
Blast:LRR
|
602 |
629 |
6e-10 |
BLAST |
|
low complexity region
|
745 |
758 |
N/A |
INTRINSIC |
|
Pfam:CARMIL_C
|
790 |
1083 |
1.1e-101 |
PFAM |
|
low complexity region
|
1131 |
1147 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1251 |
N/A |
INTRINSIC |
|
low complexity region
|
1253 |
1268 |
N/A |
INTRINSIC |
|
low complexity region
|
1287 |
1296 |
N/A |
INTRINSIC |
|
low complexity region
|
1317 |
1332 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000110398
|
| SMART Domains |
Protein: ENSMUSP00000106028
Gene: ENSMUSG00000021338
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
37 |
N/A |
INTRINSIC |
|
LRR
|
245 |
272 |
2.42e1 |
SMART |
|
LRR
|
275 |
302 |
1.04e1 |
SMART |
|
LRR
|
304 |
331 |
3.1e0 |
SMART |
|
LRR
|
336 |
363 |
5.66e1 |
SMART |
|
Blast:LRR
|
423 |
450 |
9e-8 |
BLAST |
|
LRR
|
451 |
480 |
3.15e1 |
SMART |
|
Pfam:LRR_6
|
481 |
507 |
1.9e-2 |
PFAM |
|
LRR
|
570 |
597 |
8.81e-2 |
SMART |
|
Blast:LRR
|
598 |
625 |
6e-10 |
BLAST |
|
low complexity region
|
741 |
754 |
N/A |
INTRINSIC |
|
low complexity region
|
879 |
888 |
N/A |
INTRINSIC |
|
PDB:3LK3|T
|
964 |
1076 |
1e-56 |
PDB |
|
low complexity region
|
1127 |
1143 |
N/A |
INTRINSIC |
|
low complexity region
|
1241 |
1247 |
N/A |
INTRINSIC |
|
low complexity region
|
1249 |
1264 |
N/A |
INTRINSIC |
|
low complexity region
|
1283 |
1292 |
N/A |
INTRINSIC |
|
low complexity region
|
1313 |
1325 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125901
|
| SMART Domains |
Protein: ENSMUSP00000126522
Gene: ENSMUSG00000021338
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:LRR
|
13 |
40 |
5e-8 |
BLAST |
|
Blast:LRR
|
41 |
74 |
4e-9 |
BLAST |
|
Pfam:LRR_6
|
75 |
101 |
4.4e-2 |
PFAM |
|
Pfam:LRR_6
|
164 |
187 |
1.6e-3 |
PFAM |
|
Blast:LRR
|
192 |
219 |
7e-10 |
BLAST |
|
low complexity region
|
335 |
348 |
N/A |
INTRINSIC |
|
low complexity region
|
473 |
482 |
N/A |
INTRINSIC |
|
PDB:3LK3|T
|
564 |
676 |
4e-57 |
PDB |
|
low complexity region
|
727 |
743 |
N/A |
INTRINSIC |
|
low complexity region
|
841 |
847 |
N/A |
INTRINSIC |
|
low complexity region
|
849 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
883 |
892 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
925 |
N/A |
INTRINSIC |
|
| Predicted Effect |
silent
Transcript: ENSMUST00000151566
|
| SMART Domains |
Protein: ENSMUSP00000120971
Gene: ENSMUSG00000021338
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
138 |
160 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: No abnormal phenotype was observed in a high-throughput screen, nor in a pathology assessment. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1810065E05Rik |
C |
A |
11: 58,316,582 (GRCm39) |
D187E |
probably damaging |
Het |
| Abl2 |
T |
C |
1: 156,457,630 (GRCm39) |
Y299H |
probably damaging |
Het |
| Acsl3 |
T |
A |
1: 78,659,709 (GRCm39) |
N120K |
probably damaging |
Het |
| Aldh1a1 |
A |
G |
19: 20,606,434 (GRCm39) |
K255R |
possibly damaging |
Het |
| Baz2b |
C |
T |
2: 59,750,781 (GRCm39) |
R1205H |
probably benign |
Het |
| Btbd8 |
G |
T |
5: 107,655,062 (GRCm39) |
V954L |
probably benign |
Het |
| Btbd8 |
A |
G |
5: 107,658,371 (GRCm39) |
D1647G |
probably damaging |
Het |
| Cecr2 |
A |
T |
6: 120,738,582 (GRCm39) |
N325I |
|
Het |
| Cep120 |
C |
T |
18: 53,873,161 (GRCm39) |
A57T |
probably damaging |
Het |
| Chst8 |
T |
C |
7: 34,447,628 (GRCm39) |
|
probably null |
Het |
| Cntn4 |
A |
T |
6: 106,502,421 (GRCm39) |
I393F |
probably damaging |
Het |
| Crocc |
T |
C |
4: 140,749,652 (GRCm39) |
D1494G |
probably damaging |
Het |
| Cwc25 |
T |
C |
11: 97,638,832 (GRCm39) |
E364G |
possibly damaging |
Het |
| Dnah7a |
C |
A |
1: 53,724,059 (GRCm39) |
|
probably null |
Het |
| Drg2 |
A |
G |
11: 60,345,519 (GRCm39) |
E5G |
probably benign |
Het |
| Ehd4 |
T |
C |
2: 119,921,729 (GRCm39) |
H509R |
probably damaging |
Het |
| Enam |
A |
T |
5: 88,650,186 (GRCm39) |
N565I |
probably damaging |
Het |
| Evi2a |
G |
T |
11: 79,418,249 (GRCm39) |
N120K |
probably benign |
Het |
| Faim |
A |
G |
9: 98,874,179 (GRCm39) |
T2A |
probably benign |
Het |
| Fcgbpl1 |
A |
G |
7: 27,843,833 (GRCm39) |
N907S |
probably benign |
Het |
| Fmnl1 |
T |
C |
11: 103,087,091 (GRCm39) |
V836A |
unknown |
Het |
| Fosb |
T |
C |
7: 19,039,113 (GRCm39) |
I224V |
possibly damaging |
Het |
| Frem3 |
A |
T |
8: 81,338,660 (GRCm39) |
T318S |
probably damaging |
Het |
| Gm9972 |
G |
A |
11: 42,927,631 (GRCm39) |
G93R |
unknown |
Het |
| Gtf2a1 |
A |
T |
12: 91,534,609 (GRCm39) |
I215N |
possibly damaging |
Het |
| Hs3st3b1 |
A |
G |
11: 63,812,397 (GRCm39) |
V106A |
probably benign |
Het |
| Igkv19-93 |
T |
C |
6: 68,713,485 (GRCm39) |
D48G |
probably benign |
Het |
| Itgb8 |
A |
T |
12: 119,201,443 (GRCm39) |
W31R |
probably benign |
Het |
| Kmt2d |
A |
T |
15: 98,751,985 (GRCm39) |
W1995R |
unknown |
Het |
| Lama3 |
G |
T |
18: 12,572,449 (GRCm39) |
Q551H |
probably damaging |
Het |
| Lama5 |
T |
C |
2: 179,843,588 (GRCm39) |
Y453C |
probably damaging |
Het |
| Lbhd2 |
G |
A |
12: 111,376,724 (GRCm39) |
R57H |
probably damaging |
Het |
| Lcmt2 |
A |
G |
2: 120,969,271 (GRCm39) |
V384A |
probably damaging |
Het |
| Lgsn |
T |
G |
1: 31,242,452 (GRCm39) |
L178R |
probably damaging |
Het |
| Lhcgr |
C |
T |
17: 89,065,811 (GRCm39) |
V193I |
probably benign |
Het |
| Lta4h |
T |
C |
10: 93,289,373 (GRCm39) |
M1T |
probably null |
Het |
| Ly6l |
T |
C |
15: 75,321,345 (GRCm39) |
S14P |
probably damaging |
Het |
| Met |
C |
A |
6: 17,547,011 (GRCm39) |
C881* |
probably null |
Het |
| Mettl21e |
A |
T |
1: 44,249,399 (GRCm39) |
Y86N |
probably damaging |
Het |
| Mgam |
A |
G |
6: 40,740,045 (GRCm39) |
T1673A |
probably benign |
Het |
| Mgam |
A |
T |
6: 40,633,446 (GRCm39) |
N251Y |
possibly damaging |
Het |
| Mmp27 |
T |
A |
9: 7,578,231 (GRCm39) |
V357D |
probably damaging |
Het |
| Muc2 |
A |
G |
7: 141,306,481 (GRCm39) |
E740G |
|
Het |
| Myoc |
C |
A |
1: 162,476,413 (GRCm39) |
S372R |
probably benign |
Het |
| Ncor2 |
A |
T |
5: 125,097,104 (GRCm39) |
M1358K |
|
Het |
| Nol6 |
A |
G |
4: 41,119,468 (GRCm39) |
S613P |
probably benign |
Het |
| Nuggc |
T |
A |
14: 65,855,072 (GRCm39) |
I334N |
probably damaging |
Het |
| Nxnl2 |
C |
T |
13: 51,325,542 (GRCm39) |
P62S |
probably damaging |
Het |
| Ogfod1 |
C |
T |
8: 94,764,067 (GRCm39) |
H51Y |
possibly damaging |
Het |
| Olfml1 |
T |
A |
7: 107,189,530 (GRCm39) |
D198E |
possibly damaging |
Het |
| Or2t26 |
A |
C |
11: 49,039,945 (GRCm39) |
N287T |
probably damaging |
Het |
| Ovch2 |
C |
T |
7: 107,393,577 (GRCm39) |
R183H |
possibly damaging |
Het |
| Plxnd1 |
A |
T |
6: 115,937,798 (GRCm39) |
L1516Q |
probably damaging |
Het |
| Pramel27 |
A |
G |
4: 143,578,451 (GRCm39) |
N237S |
possibly damaging |
Het |
| Prrc2c |
A |
G |
1: 162,507,543 (GRCm39) |
V2448A |
possibly damaging |
Het |
| Rexo5 |
C |
T |
7: 119,417,636 (GRCm39) |
T212I |
probably damaging |
Het |
| Rgl2 |
C |
T |
17: 34,152,403 (GRCm39) |
R367W |
probably damaging |
Het |
| Rnf213 |
T |
G |
11: 119,328,818 (GRCm39) |
I2030S |
|
Het |
| Rtf1 |
C |
T |
2: 119,505,580 (GRCm39) |
A11V |
unknown |
Het |
| Setdb1 |
T |
G |
3: 95,245,985 (GRCm39) |
T647P |
probably damaging |
Het |
| Shisa6 |
G |
C |
11: 66,393,480 (GRCm39) |
P272R |
possibly damaging |
Het |
| Slc25a54 |
G |
T |
3: 109,023,817 (GRCm39) |
G471* |
probably null |
Het |
| Slc30a1 |
A |
G |
1: 191,641,544 (GRCm39) |
T397A |
probably benign |
Het |
| Slc7a14 |
A |
G |
3: 31,281,302 (GRCm39) |
F336S |
possibly damaging |
Het |
| Slitrk3 |
C |
T |
3: 72,957,798 (GRCm39) |
V325I |
possibly damaging |
Het |
| Sptan1 |
A |
G |
2: 29,876,941 (GRCm39) |
Y361C |
probably damaging |
Het |
| Stard9 |
A |
G |
2: 120,528,984 (GRCm39) |
D1747G |
probably benign |
Het |
| Taf3 |
T |
C |
2: 9,956,253 (GRCm39) |
E638G |
probably damaging |
Het |
| Tbc1d8 |
T |
C |
1: 39,411,614 (GRCm39) |
D1074G |
probably benign |
Het |
| Tecrl |
G |
A |
5: 83,502,754 (GRCm39) |
H32Y |
probably benign |
Het |
| Tgm3 |
T |
A |
2: 129,866,481 (GRCm39) |
M133K |
probably benign |
Het |
| Tmem131 |
A |
G |
1: 36,880,685 (GRCm39) |
F195S |
probably damaging |
Het |
| Tmem82 |
T |
C |
4: 141,342,261 (GRCm39) |
I314V |
possibly damaging |
Het |
| Trappc10 |
T |
C |
10: 78,043,327 (GRCm39) |
E555G |
probably damaging |
Het |
| Ubn2 |
A |
T |
6: 38,429,811 (GRCm39) |
K176* |
probably null |
Het |
| Ucp1 |
G |
A |
8: 84,020,531 (GRCm39) |
G114R |
probably benign |
Het |
| Unc5c |
A |
G |
3: 141,383,751 (GRCm39) |
D43G |
probably damaging |
Het |
| Vmn2r3 |
C |
T |
3: 64,168,825 (GRCm39) |
V571M |
possibly damaging |
Het |
| Vwa3a |
A |
T |
7: 120,385,688 (GRCm39) |
I677L |
probably benign |
Het |
| Wdr48 |
T |
C |
9: 119,740,147 (GRCm39) |
S319P |
probably damaging |
Het |
|
| Other mutations in Carmil1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00096:Carmil1
|
APN |
13 |
24,295,821 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL00392:Carmil1
|
APN |
13 |
24,278,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00943:Carmil1
|
APN |
13 |
24,295,869 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL01375:Carmil1
|
APN |
13 |
24,278,454 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL02043:Carmil1
|
APN |
13 |
24,208,299 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02122:Carmil1
|
APN |
13 |
24,220,541 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02178:Carmil1
|
APN |
13 |
24,278,386 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02264:Carmil1
|
APN |
13 |
24,259,699 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02269:Carmil1
|
APN |
13 |
24,339,393 (GRCm39) |
nonsense |
probably null |
|
|
IGL02546:Carmil1
|
APN |
13 |
24,299,482 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02740:Carmil1
|
APN |
13 |
24,278,501 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02876:Carmil1
|
APN |
13 |
24,338,651 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02976:Carmil1
|
APN |
13 |
24,276,534 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL03012:Carmil1
|
APN |
13 |
24,220,355 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL03107:Carmil1
|
APN |
13 |
24,278,438 (GRCm39) |
missense |
probably damaging |
0.99 |
|
H8562:Carmil1
|
UTSW |
13 |
24,248,630 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0085:Carmil1
|
UTSW |
13 |
24,209,850 (GRCm39) |
missense |
probably benign |
|
|
R0119:Carmil1
|
UTSW |
13 |
24,266,003 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0166:Carmil1
|
UTSW |
13 |
24,283,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0299:Carmil1
|
UTSW |
13 |
24,266,003 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0304:Carmil1
|
UTSW |
13 |
24,323,324 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0335:Carmil1
|
UTSW |
13 |
24,257,966 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0369:Carmil1
|
UTSW |
13 |
24,266,003 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0462:Carmil1
|
UTSW |
13 |
24,206,494 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1203:Carmil1
|
UTSW |
13 |
24,282,989 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1540:Carmil1
|
UTSW |
13 |
24,283,037 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1730:Carmil1
|
UTSW |
13 |
24,225,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1770:Carmil1
|
UTSW |
13 |
24,357,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1831:Carmil1
|
UTSW |
13 |
24,348,862 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1893:Carmil1
|
UTSW |
13 |
24,208,446 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2099:Carmil1
|
UTSW |
13 |
24,357,650 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2153:Carmil1
|
UTSW |
13 |
24,325,656 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2296:Carmil1
|
UTSW |
13 |
24,299,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2869:Carmil1
|
UTSW |
13 |
24,229,051 (GRCm39) |
synonymous |
silent |
|
|
R2872:Carmil1
|
UTSW |
13 |
24,229,051 (GRCm39) |
synonymous |
silent |
|
|
R3113:Carmil1
|
UTSW |
13 |
24,253,740 (GRCm39) |
missense |
probably benign |
0.22 |
|
R3508:Carmil1
|
UTSW |
13 |
24,203,659 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R3780:Carmil1
|
UTSW |
13 |
24,321,152 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3954:Carmil1
|
UTSW |
13 |
24,197,390 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4027:Carmil1
|
UTSW |
13 |
24,251,206 (GRCm39) |
splice site |
probably benign |
|
|
R4086:Carmil1
|
UTSW |
13 |
24,208,444 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4647:Carmil1
|
UTSW |
13 |
24,321,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4792:Carmil1
|
UTSW |
13 |
24,325,659 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R4792:Carmil1
|
UTSW |
13 |
24,251,173 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5012:Carmil1
|
UTSW |
13 |
24,208,403 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5166:Carmil1
|
UTSW |
13 |
24,338,966 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5199:Carmil1
|
UTSW |
13 |
24,295,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5330:Carmil1
|
UTSW |
13 |
24,209,929 (GRCm39) |
splice site |
probably null |
|
|
R5472:Carmil1
|
UTSW |
13 |
24,339,454 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5478:Carmil1
|
UTSW |
13 |
24,296,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5496:Carmil1
|
UTSW |
13 |
24,339,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5775:Carmil1
|
UTSW |
13 |
24,460,520 (GRCm39) |
missense |
probably benign |
|
|
R5789:Carmil1
|
UTSW |
13 |
24,305,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5794:Carmil1
|
UTSW |
13 |
24,276,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5977:Carmil1
|
UTSW |
13 |
24,253,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6127:Carmil1
|
UTSW |
13 |
24,220,335 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6128:Carmil1
|
UTSW |
13 |
24,197,177 (GRCm39) |
nonsense |
probably null |
|
|
R6403:Carmil1
|
UTSW |
13 |
24,265,950 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6450:Carmil1
|
UTSW |
13 |
24,220,547 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6451:Carmil1
|
UTSW |
13 |
24,276,541 (GRCm39) |
nonsense |
probably null |
|
|
R6684:Carmil1
|
UTSW |
13 |
24,206,525 (GRCm39) |
missense |
unknown |
|
|
R6891:Carmil1
|
UTSW |
13 |
24,325,706 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6902:Carmil1
|
UTSW |
13 |
24,299,528 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R6924:Carmil1
|
UTSW |
13 |
24,259,667 (GRCm39) |
nonsense |
probably null |
|
|
R6946:Carmil1
|
UTSW |
13 |
24,299,528 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R7038:Carmil1
|
UTSW |
13 |
24,323,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7179:Carmil1
|
UTSW |
13 |
24,204,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7286:Carmil1
|
UTSW |
13 |
24,197,377 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7397:Carmil1
|
UTSW |
13 |
24,228,294 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7412:Carmil1
|
UTSW |
13 |
24,282,793 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7611:Carmil1
|
UTSW |
13 |
24,197,315 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7642:Carmil1
|
UTSW |
13 |
24,251,189 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7827:Carmil1
|
UTSW |
13 |
24,220,421 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7890:Carmil1
|
UTSW |
13 |
24,197,215 (GRCm39) |
missense |
|
|
|
R8014:Carmil1
|
UTSW |
13 |
24,220,304 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8068:Carmil1
|
UTSW |
13 |
24,259,711 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8214:Carmil1
|
UTSW |
13 |
24,228,215 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8247:Carmil1
|
UTSW |
13 |
24,282,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8272:Carmil1
|
UTSW |
13 |
24,220,562 (GRCm39) |
missense |
probably benign |
|
|
R8318:Carmil1
|
UTSW |
13 |
24,220,442 (GRCm39) |
missense |
probably benign |
|
|
R8361:Carmil1
|
UTSW |
13 |
24,251,113 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8469:Carmil1
|
UTSW |
13 |
24,296,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8558:Carmil1
|
UTSW |
13 |
24,209,863 (GRCm39) |
missense |
probably benign |
|
|
R8698:Carmil1
|
UTSW |
13 |
24,220,229 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8722:Carmil1
|
UTSW |
13 |
24,220,568 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8836:Carmil1
|
UTSW |
13 |
24,339,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8915:Carmil1
|
UTSW |
13 |
24,325,709 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8931:Carmil1
|
UTSW |
13 |
24,338,704 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8932:Carmil1
|
UTSW |
13 |
24,197,179 (GRCm39) |
missense |
|
|
|
R9004:Carmil1
|
UTSW |
13 |
24,225,662 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9041:Carmil1
|
UTSW |
13 |
24,282,793 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R9103:Carmil1
|
UTSW |
13 |
24,295,836 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9224:Carmil1
|
UTSW |
13 |
24,292,512 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9428:Carmil1
|
UTSW |
13 |
24,295,834 (GRCm39) |
nonsense |
probably null |
|
|
R9460:Carmil1
|
UTSW |
13 |
24,253,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9502:Carmil1
|
UTSW |
13 |
24,323,357 (GRCm39) |
missense |
probably benign |
|
|
R9548:Carmil1
|
UTSW |
13 |
24,460,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0025:Carmil1
|
UTSW |
13 |
24,283,026 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
Z1088:Carmil1
|
UTSW |
13 |
24,228,165 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCCCATGGAATAATTGCTGG -3'
(R):5'- CGTGTCGAAGCTTAATGCAG -3'
Sequencing Primer
(F):5'- GGCTTTTTGTTGAAGGCATAAGAAAC -3'
(R):5'- GCTTAATGCAGGTTTGTTTCTGAAAC -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation