Incidental Mutation 'R7284:Kirrel1'
| ID |
565851 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kirrel1
|
| Ensembl Gene |
ENSMUSG00000041734 |
| Gene Name |
kirre like nephrin family adhesion molecule 1 |
| Synonyms |
6720469N11Rik, Neph1, Kirrel1, Kirrel |
| MMRRC Submission |
045392-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7284 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
86985900-87082054 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 86990694 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 709
(D709E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125525
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041732]
[ENSMUST00000107618]
[ENSMUST00000159976]
|
| AlphaFold |
Q80W68 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041732
|
| SMART Domains |
Protein: ENSMUSP00000043756
Gene: ENSMUSG00000041734
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000107618
AA Change: D709E
PolyPhen 2
Score 0.024 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000103243
Gene: ENSMUSG00000041734
AA Change: D709E
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159976
AA Change: D709E
PolyPhen 2
Score 0.024 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000125525
Gene: ENSMUSG00000041734
AA Change: D709E
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0846 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.3%
|
| Validation Efficiency |
99% (77/78) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a gene trap insertion exhibit postnatal lethality and are small and sickly. Glomerular and tubular defects in the kidney result in severe proteinuria. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(121) : Targeted, other(2) Gene trapped(119) |
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2900092C05Rik |
G |
T |
7: 12,246,605 (GRCm39) |
E34* |
probably null |
Het |
| 4933421I07Rik |
C |
T |
7: 42,097,404 (GRCm39) |
R30H |
probably damaging |
Het |
| AB124611 |
C |
A |
9: 21,450,400 (GRCm39) |
Q158K |
probably benign |
Het |
| Abcc3 |
C |
T |
11: 94,247,873 (GRCm39) |
A1207T |
probably benign |
Het |
| Abcc9 |
A |
T |
6: 142,628,643 (GRCm39) |
L367Q |
probably damaging |
Het |
| Aftph |
T |
C |
11: 20,676,812 (GRCm39) |
K266E |
probably benign |
Het |
| Akap9 |
T |
A |
5: 4,006,246 (GRCm39) |
D190E |
probably damaging |
Het |
| Angel1 |
G |
T |
12: 86,767,298 (GRCm39) |
D359E |
probably damaging |
Het |
| Ano6 |
T |
C |
15: 95,846,184 (GRCm39) |
I474T |
probably damaging |
Het |
| Atp2c1 |
A |
T |
9: 105,398,008 (GRCm39) |
|
probably null |
Het |
| Best1 |
T |
C |
19: 9,963,737 (GRCm39) |
|
probably null |
Het |
| Bhlha9 |
A |
G |
11: 76,563,492 (GRCm39) |
S40G |
probably benign |
Het |
| Cabin1 |
G |
A |
10: 75,530,668 (GRCm39) |
R178C |
|
Het |
| Ccnb1ip1 |
A |
G |
14: 51,029,736 (GRCm39) |
Y109H |
probably damaging |
Het |
| Col14a1 |
T |
C |
15: 55,381,715 (GRCm39) |
S1763P |
probably damaging |
Het |
| Dars1 |
T |
C |
1: 128,300,004 (GRCm39) |
T327A |
probably benign |
Het |
| Dhx8 |
T |
C |
11: 101,645,648 (GRCm39) |
Y889H |
probably damaging |
Het |
| Dlg4 |
T |
A |
11: 69,932,908 (GRCm39) |
Y523* |
probably null |
Het |
| Dnah10 |
A |
T |
5: 124,909,662 (GRCm39) |
D4484V |
probably benign |
Het |
| Dnah9 |
A |
T |
11: 65,881,302 (GRCm39) |
M2591K |
probably damaging |
Het |
| Dock2 |
T |
C |
11: 34,180,672 (GRCm39) |
E1715G |
probably benign |
Het |
| Dym |
A |
G |
18: 75,252,242 (GRCm39) |
Y336C |
possibly damaging |
Het |
| Ezh2 |
A |
G |
6: 47,521,453 (GRCm39) |
M439T |
probably benign |
Het |
| Folr1 |
T |
G |
7: 101,508,677 (GRCm39) |
N83H |
possibly damaging |
Het |
| Ganab |
T |
C |
19: 8,889,904 (GRCm39) |
L656P |
probably damaging |
Het |
| Gmnc |
T |
C |
16: 26,779,542 (GRCm39) |
H161R |
probably benign |
Het |
| Gria4 |
A |
G |
9: 4,472,017 (GRCm39) |
Y491H |
probably damaging |
Het |
| Heatr3 |
T |
A |
8: 88,883,402 (GRCm39) |
C412S |
possibly damaging |
Het |
| Hmgcr |
A |
C |
13: 96,789,173 (GRCm39) |
V716G |
probably damaging |
Het |
| Igsf9 |
A |
G |
1: 172,324,479 (GRCm39) |
D799G |
probably damaging |
Het |
| Ikbkb |
T |
C |
8: 23,158,976 (GRCm39) |
T501A |
probably benign |
Het |
| Kbtbd3 |
C |
T |
9: 4,330,690 (GRCm39) |
R355* |
probably null |
Het |
| Kcna7 |
T |
A |
7: 45,058,652 (GRCm39) |
I313N |
probably damaging |
Het |
| Klb |
T |
A |
5: 65,540,821 (GRCm39) |
S971R |
probably benign |
Het |
| Krtap4-13 |
A |
T |
11: 99,700,238 (GRCm39) |
C140* |
probably null |
Het |
| Lacc1 |
A |
T |
14: 77,268,309 (GRCm39) |
L334Q |
probably damaging |
Het |
| Map6d1 |
T |
A |
16: 20,059,775 (GRCm39) |
R97* |
probably null |
Het |
| Mgat5b |
T |
C |
11: 116,835,746 (GRCm39) |
S129P |
probably damaging |
Het |
| Mmp1a |
TG |
TGG |
9: 7,465,083 (GRCm38) |
|
probably null |
Het |
| Myh9 |
G |
A |
15: 77,671,796 (GRCm39) |
R432C |
probably damaging |
Het |
| Ncf4 |
A |
G |
15: 78,144,902 (GRCm39) |
T236A |
probably benign |
Het |
| Neb |
T |
C |
2: 52,148,804 (GRCm39) |
D2581G |
probably damaging |
Het |
| Nid1 |
T |
A |
13: 13,663,675 (GRCm39) |
M778K |
probably benign |
Het |
| Npas2 |
A |
G |
1: 39,363,548 (GRCm39) |
D209G |
probably benign |
Het |
| Nploc4 |
C |
T |
11: 120,307,196 (GRCm39) |
V181I |
possibly damaging |
Het |
| Nrcam |
A |
T |
12: 44,610,817 (GRCm39) |
I506F |
probably damaging |
Het |
| Or52w1 |
T |
A |
7: 105,017,752 (GRCm39) |
M73K |
probably damaging |
Het |
| Or5h27 |
A |
G |
16: 59,006,331 (GRCm39) |
*172Q |
probably null |
Het |
| Or6c3b |
T |
C |
10: 129,527,220 (GRCm39) |
N230S |
probably benign |
Het |
| Pask |
T |
A |
1: 93,248,391 (GRCm39) |
Q970L |
probably benign |
Het |
| Pfkfb4 |
T |
C |
9: 108,840,308 (GRCm39) |
I308T |
possibly damaging |
Het |
| Pla2g4d |
A |
T |
2: 120,114,617 (GRCm39) |
L38Q |
probably damaging |
Het |
| Pld1 |
A |
G |
3: 28,185,882 (GRCm39) |
T1036A |
possibly damaging |
Het |
| Pom121l2 |
A |
G |
13: 22,166,775 (GRCm39) |
T349A |
probably damaging |
Het |
| Ppp1r13b |
A |
G |
12: 111,801,400 (GRCm39) |
I551T |
possibly damaging |
Het |
| Prps1l1 |
A |
G |
12: 35,035,317 (GRCm39) |
N144S |
possibly damaging |
Het |
| Prss56 |
A |
G |
1: 87,113,123 (GRCm39) |
N179S |
probably null |
Het |
| Prune2 |
T |
C |
19: 17,097,250 (GRCm39) |
L918P |
probably damaging |
Het |
| Ptprz1 |
C |
T |
6: 23,000,097 (GRCm39) |
T729I |
probably damaging |
Het |
| Relch |
T |
A |
1: 105,662,308 (GRCm39) |
H942Q |
probably benign |
Het |
| Rrp7a |
T |
C |
15: 83,006,071 (GRCm39) |
T60A |
probably damaging |
Het |
| Snx27 |
A |
G |
3: 94,431,498 (GRCm39) |
Y299H |
probably damaging |
Het |
| Spaca3 |
G |
T |
11: 80,754,847 (GRCm39) |
R96L |
possibly damaging |
Het |
| Stat1 |
A |
G |
1: 52,188,081 (GRCm39) |
N495S |
probably benign |
Het |
| Tas2r130 |
T |
C |
6: 131,607,270 (GRCm39) |
N175S |
probably benign |
Het |
| Tcaf2 |
A |
G |
6: 42,606,472 (GRCm39) |
L494P |
probably damaging |
Het |
| Tdrd12 |
C |
A |
7: 35,179,561 (GRCm39) |
|
probably null |
Het |
| Thbs1 |
A |
G |
2: 117,949,837 (GRCm39) |
N604S |
probably damaging |
Het |
| Togaram1 |
T |
C |
12: 65,055,454 (GRCm39) |
F1482L |
probably benign |
Het |
| Trhr2 |
A |
T |
8: 123,087,114 (GRCm39) |
S109T |
probably damaging |
Het |
| Trpc3 |
A |
T |
3: 36,678,562 (GRCm39) |
M841K |
probably damaging |
Het |
| Tubgcp5 |
C |
T |
7: 55,473,315 (GRCm39) |
R798C |
probably benign |
Het |
| Xirp2 |
T |
A |
2: 67,347,173 (GRCm39) |
M3138K |
probably benign |
Het |
| Zdhhc4 |
G |
A |
5: 143,307,646 (GRCm39) |
T125I |
probably benign |
Het |
| Zfp239 |
T |
A |
6: 117,848,716 (GRCm39) |
C151* |
probably null |
Het |
| Zfp473 |
C |
T |
7: 44,382,627 (GRCm39) |
E569K |
not run |
Het |
| Zzef1 |
T |
A |
11: 72,777,516 (GRCm39) |
D1782E |
probably damaging |
Het |
|
| Other mutations in Kirrel1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01310:Kirrel1
|
APN |
3 |
86,997,182 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL01865:Kirrel1
|
APN |
3 |
86,993,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01875:Kirrel1
|
APN |
3 |
87,003,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02337:Kirrel1
|
APN |
3 |
86,996,519 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL02724:Kirrel1
|
APN |
3 |
86,997,780 (GRCm39) |
nonsense |
probably null |
|
|
IGL02825:Kirrel1
|
APN |
3 |
86,996,595 (GRCm39) |
splice site |
probably benign |
|
|
IGL02826:Kirrel1
|
APN |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03102:Kirrel1
|
APN |
3 |
86,990,807 (GRCm39) |
missense |
probably damaging |
0.98 |
|
D4043:Kirrel1
|
UTSW |
3 |
86,990,510 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0360:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0364:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0421:Kirrel1
|
UTSW |
3 |
86,990,914 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0503:Kirrel1
|
UTSW |
3 |
87,005,109 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1112:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1116:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1144:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1190:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1226:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1501:Kirrel1
|
UTSW |
3 |
86,997,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1538:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1546:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1628:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1630:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1631:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1664:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1671:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1695:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1769:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1807:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1808:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1840:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1995:Kirrel1
|
UTSW |
3 |
87,003,093 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2014:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2086:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2108:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2354:Kirrel1
|
UTSW |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2407:Kirrel1
|
UTSW |
3 |
86,992,150 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2904:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2905:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2958:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2959:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2960:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2961:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3026:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3028:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3034:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R3149:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3195:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3196:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3499:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3699:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3720:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3721:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3788:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3793:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3877:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3901:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3910:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3911:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3912:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3913:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3930:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3931:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4022:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4067:Kirrel1
|
UTSW |
3 |
86,995,774 (GRCm39) |
nonsense |
probably null |
|
|
R4077:Kirrel1
|
UTSW |
3 |
86,992,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4198:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4328:Kirrel1
|
UTSW |
3 |
86,992,081 (GRCm39) |
intron |
probably benign |
|
|
R4355:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4363:Kirrel1
|
UTSW |
3 |
86,997,792 (GRCm39) |
nonsense |
probably null |
|
|
R4378:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4386:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4460:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4468:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4469:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4650:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4652:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4734:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4748:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4749:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R5304:Kirrel1
|
UTSW |
3 |
86,996,902 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5534:Kirrel1
|
UTSW |
3 |
86,997,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5604:Kirrel1
|
UTSW |
3 |
86,996,462 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7199:Kirrel1
|
UTSW |
3 |
86,990,695 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7221:Kirrel1
|
UTSW |
3 |
86,993,704 (GRCm39) |
nonsense |
probably null |
|
|
R7332:Kirrel1
|
UTSW |
3 |
86,995,705 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7369:Kirrel1
|
UTSW |
3 |
87,048,391 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7371:Kirrel1
|
UTSW |
3 |
86,995,729 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7508:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R7566:Kirrel1
|
UTSW |
3 |
86,995,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7567:Kirrel1
|
UTSW |
3 |
87,002,988 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7621:Kirrel1
|
UTSW |
3 |
86,995,528 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8030:Kirrel1
|
UTSW |
3 |
87,005,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8141:Kirrel1
|
UTSW |
3 |
86,993,735 (GRCm39) |
nonsense |
probably null |
|
|
R8261:Kirrel1
|
UTSW |
3 |
86,995,309 (GRCm39) |
intron |
probably benign |
|
|
R8477:Kirrel1
|
UTSW |
3 |
86,992,138 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8512:Kirrel1
|
UTSW |
3 |
86,995,534 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8954:Kirrel1
|
UTSW |
3 |
86,997,173 (GRCm39) |
missense |
probably benign |
0.25 |
|
R8987:Kirrel1
|
UTSW |
3 |
86,992,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9058:Kirrel1
|
UTSW |
3 |
86,992,442 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9146:Kirrel1
|
UTSW |
3 |
87,003,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9311:Kirrel1
|
UTSW |
3 |
87,005,123 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9527:Kirrel1
|
UTSW |
3 |
86,996,912 (GRCm39) |
nonsense |
probably null |
|
|
R9629:Kirrel1
|
UTSW |
3 |
87,003,025 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Kirrel1
|
UTSW |
3 |
86,991,182 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CCAGCCTCTACACATGAGTCTG -3'
(R):5'- TGTATGCTGACTACCGTGCC -3'
Sequencing Primer
(F):5'- AATCGCTGGCCATAGTCTGAG -3'
(R):5'- TGACTACCGTGCCCCTGG -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation