Mutagenetix > Incidental Mutation

Incidental Mutation 'R7287:Nav2'

566093

Institutional Source

Beutler Lab

Gene Symbol

Nav2

Ensembl Gene

ENSMUSG00000052512

Gene Name

neuron navigator 2

Synonyms

Rainb1, HELAD1, Unc53H2, RAINB2, 5330421F07Rik, POMFIL2

MMRRC Submission

045321-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.483) question?

Stock #

R7287 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

48908716-49610090 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 49420328 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Aspartic acid at position 311 (N311D)

Ref Sequence

ENSEMBL: ENSMUSP00000067448 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000064395] [ENSMUST00000183659] [ENSMUST00000184124] [ENSMUST00000184945]

AlphaFold

E9Q842

Predicted Effect

probably benign
Transcript: ENSMUST00000064395
AA Change: N311D

PolyPhen 2 Score 0.012 (Sensitivity: 0.96; Specificity: 0.78)

SMART Domains

Protein: ENSMUSP00000067448
Gene: ENSMUSG00000052512
AA Change: N311D

Domain	Start	End	E-Value	Type
CH	84	187	1.58e-13	SMART
low complexity region	202	210	N/A	INTRINSIC
low complexity region	297	310	N/A	INTRINSIC
low complexity region	337	348	N/A	INTRINSIC
low complexity region	412	424	N/A	INTRINSIC
coiled coil region	486	516	N/A	INTRINSIC
low complexity region	580	591	N/A	INTRINSIC
low complexity region	613	625	N/A	INTRINSIC
low complexity region	640	662	N/A	INTRINSIC
low complexity region	846	857	N/A	INTRINSIC
low complexity region	920	944	N/A	INTRINSIC
low complexity region	947	967	N/A	INTRINSIC
low complexity region	990	1004	N/A	INTRINSIC
low complexity region	1062	1074	N/A	INTRINSIC
low complexity region	1343	1360	N/A	INTRINSIC
low complexity region	1368	1385	N/A	INTRINSIC
low complexity region	1417	1432	N/A	INTRINSIC
low complexity region	1454	1466	N/A	INTRINSIC
low complexity region	1526	1540	N/A	INTRINSIC
low complexity region	1614	1628	N/A	INTRINSIC
coiled coil region	1630	1717	N/A	INTRINSIC
low complexity region	1789	1800	N/A	INTRINSIC
coiled coil region	1841	1909	N/A	INTRINSIC
AAA	2093	2247	1.69e-5	SMART
low complexity region	2404	2430	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000183659
AA Change: N250D

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000139309
Gene: ENSMUSG00000052512
AA Change: N250D

Domain	Start	End	E-Value	Type
low complexity region	2	11	N/A	INTRINSIC
CH	23	126	6.19e-16	SMART
low complexity region	141	149	N/A	INTRINSIC
low complexity region	236	249	N/A	INTRINSIC
low complexity region	276	287	N/A	INTRINSIC
low complexity region	351	363	N/A	INTRINSIC
coiled coil region	425	455	N/A	INTRINSIC
low complexity region	519	530	N/A	INTRINSIC
low complexity region	552	564	N/A	INTRINSIC
low complexity region	579	601	N/A	INTRINSIC
low complexity region	785	796	N/A	INTRINSIC
low complexity region	859	883	N/A	INTRINSIC
low complexity region	886	906	N/A	INTRINSIC
low complexity region	929	943	N/A	INTRINSIC
low complexity region	1001	1013	N/A	INTRINSIC
low complexity region	1282	1299	N/A	INTRINSIC
low complexity region	1307	1324	N/A	INTRINSIC
low complexity region	1356	1371	N/A	INTRINSIC
low complexity region	1393	1405	N/A	INTRINSIC
low complexity region	1465	1479	N/A	INTRINSIC
low complexity region	1553	1567	N/A	INTRINSIC
coiled coil region	1569	1656	N/A	INTRINSIC
low complexity region	1728	1739	N/A	INTRINSIC
coiled coil region	1780	1848	N/A	INTRINSIC
AAA	2032	2186	1.69e-5	SMART
low complexity region	2343	2369	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000184124

Predicted Effect

probably benign
Transcript: ENSMUST00000184945
AA Change: N311D

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000139045
Gene: ENSMUSG00000052512
AA Change: N311D

Domain	Start	End	E-Value	Type
CH	84	187	1.58e-13	SMART
low complexity region	202	210	N/A	INTRINSIC
low complexity region	297	310	N/A	INTRINSIC
low complexity region	337	348	N/A	INTRINSIC
low complexity region	412	424	N/A	INTRINSIC
coiled coil region	486	516	N/A	INTRINSIC
low complexity region	580	591	N/A	INTRINSIC
low complexity region	613	625	N/A	INTRINSIC
low complexity region	640	662	N/A	INTRINSIC
low complexity region	846	857	N/A	INTRINSIC
low complexity region	920	944	N/A	INTRINSIC
low complexity region	947	967	N/A	INTRINSIC
low complexity region	990	1004	N/A	INTRINSIC
low complexity region	1062	1074	N/A	INTRINSIC
low complexity region	1343	1360	N/A	INTRINSIC
low complexity region	1368	1385	N/A	INTRINSIC
low complexity region	1417	1432	N/A	INTRINSIC
low complexity region	1454	1466	N/A	INTRINSIC
low complexity region	1526	1540	N/A	INTRINSIC
low complexity region	1614	1628	N/A	INTRINSIC
coiled coil region	1630	1717	N/A	INTRINSIC
low complexity region	1789	1800	N/A	INTRINSIC
coiled coil region	1841	1909	N/A	INTRINSIC
AAA	2093	2247	1.69e-5	SMART
low complexity region	2404	2430	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.4%

Validation Efficiency

100% (71/71)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
PHENOTYPE: Homozygous null mice display impaired olfaction and hearing, increased latency in a hot plate test, degeneration of the optic nerve, decreased exploration in new environments, and weight loss. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 69 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca3	A	G	17: 24,385,887 (GRCm38)	D656G	possibly damaging	Het
Abcc3	C	T	11: 94,357,047 (GRCm38)	A1207T	probably benign	Het
Abcc8	T	C	7: 46,113,110 (GRCm38)	H1209R	probably damaging	Het
Adam26a	T	C	8: 43,570,343 (GRCm38)	T37A	possibly damaging	Het
Adamts9	C	T	6: 92,890,003 (GRCm38)	R685Q	possibly damaging	Het
Anapc7	T	A	5: 122,433,436 (GRCm38)	N191K	probably benign	Het
Ankrd26	C	T	6: 118,549,637 (GRCm38)		probably null	Het
Ap5z1	T	C	5: 142,474,047 (GRCm38)	L484P	probably damaging	Het
Arhgap32	A	G	9: 32,152,697 (GRCm38)	D77G		Het
Atp10a	T	A	7: 58,827,269 (GRCm38)	D1213E	probably damaging	Het
B3gnt8	T	C	7: 25,628,970 (GRCm38)	L275P	probably damaging	Het
Bltp2	G	A	11: 78,272,883 (GRCm38)	R1059H	possibly damaging	Het
Cab39	A	G	1: 85,818,461 (GRCm38)	E21G	probably benign	Het
Capn15	G	T	17: 25,960,455 (GRCm38)	S948R	probably damaging	Het
Cbarp	T	C	10: 80,137,320 (GRCm38)	T15A	unknown	Het
Ccdc81	C	T	7: 89,893,123 (GRCm38)	A182T	probably damaging	Het
Ccpg1	A	G	9: 73,015,406 (GRCm38)	H766R	probably benign	Het
Cfl1	T	C	19: 5,492,534 (GRCm38)	V14A	probably benign	Het
Chd6	A	G	2: 161,008,392 (GRCm38)	I875T	probably benign	Het
Cidec	T	A	6: 113,428,398 (GRCm38)	E121D	probably benign	Het
Clpx	C	A	9: 65,300,013 (GRCm38)	Y64*	probably null	Het
Cntn1	T	A	15: 92,245,952 (GRCm38)		probably null	Het
Cyp24a1	A	G	2: 170,485,906 (GRCm38)	L472P	probably damaging	Het
Dcdc2c	G	T	12: 28,516,686 (GRCm38)	D159E	probably benign	Het
Emp1	T	C	6: 135,380,169 (GRCm38)	F82L	probably benign	Het
Fem1b	T	C	9: 62,796,122 (GRCm38)	T619A	probably benign	Het
Fgf15	A	T	7: 144,896,794 (GRCm38)	D39V	probably benign	Het
Galnt12	T	G	4: 47,108,525 (GRCm38)	F221V	probably damaging	Het
Herc6	A	G	6: 57,651,980 (GRCm38)		probably null	Het
Hspg2	G	A	4: 137,529,556 (GRCm38)	V1537I	probably benign	Het
Ido2	T	C	8: 24,535,138 (GRCm38)		probably null	Het
Insr	G	A	8: 3,169,717 (GRCm38)	T935I	probably benign	Het
Itgax	G	A	7: 128,148,505 (GRCm38)	C1031Y	probably damaging	Het
Kif13a	C	T	13: 46,752,455 (GRCm38)	V671M	possibly damaging	Het
Kmt5b	T	C	19: 3,804,501 (GRCm38)	Y255H	possibly damaging	Het
Lrriq1	A	T	10: 103,216,016 (GRCm38)	Y292N	probably benign	Het
Mrpl37	A	G	4: 107,060,520 (GRCm38)	F318S	probably damaging	Het
Nbeal1	G	C	1: 60,237,151 (GRCm38)	V684L	probably benign	Het
Nlrp9b	T	C	7: 20,028,456 (GRCm38)	C673R	probably damaging	Het
Npnt	A	G	3: 132,906,802 (GRCm38)	V74A	probably benign	Het
Or10ak12	T	A	4: 118,809,742 (GRCm38)	T41S	probably benign	Het
Or1e19	T	A	11: 73,425,843 (GRCm38)	I47F	probably benign	Het
Plce1	A	T	19: 38,701,903 (GRCm38)	Q677L	probably benign	Het
Pmel	C	T	10: 128,715,226 (GRCm38)	Q113*	probably null	Het
Pom121l2	T	A	13: 21,984,332 (GRCm38)	F924L	probably benign	Het
Poteg	G	A	8: 27,453,344 (GRCm38)	R214K	probably null	Het
Pprc1	G	T	19: 46,071,354 (GRCm38)	S1480I	unknown	Het
Secisbp2l	A	G	2: 125,740,369 (GRCm38)	S1056P	probably benign	Het
Selenoo	T	C	15: 89,098,700 (GRCm38)	F477L	probably benign	Het
Senp2	A	G	16: 22,018,364 (GRCm38)	D121G	probably damaging	Het
Slc25a11	T	C	11: 70,645,355 (GRCm38)	D211G	probably benign	Het
Slc44a2	A	G	9: 21,342,456 (GRCm38)	D131G	probably benign	Het
Tcf25	G	A	8: 123,373,972 (GRCm38)	A34T	possibly damaging	Het
Tm9sf3	A	G	19: 41,217,379 (GRCm38)	Y530H	probably damaging	Het
Tmco3	G	A	8: 13,319,605 (GRCm38)		probably null	Het
Tmem132d	G	T	5: 127,984,351 (GRCm38)	Q396K	probably damaging	Het
Tmem154	A	G	3: 84,690,563 (GRCm38)	T136A	possibly damaging	Het
Tnrc6b	A	G	15: 80,879,541 (GRCm38)	T415A	possibly damaging	Het
Tonsl	T	C	15: 76,633,725 (GRCm38)		probably null	Het
Ttyh1	T	C	7: 4,125,658 (GRCm38)	Y185H	probably benign	Het
Ufl1	T	A	4: 25,254,852 (GRCm38)	T535S	probably benign	Het
Vmn1r15	T	C	6: 57,258,216 (GRCm38)	L23P	possibly damaging	Het
Vmn2r25	T	A	6: 123,852,081 (GRCm38)	H78L	possibly damaging	Het
Vmn2r68	T	C	7: 85,222,252 (GRCm38)	T608A	probably benign	Het
Vwf	A	G	6: 125,637,467 (GRCm38)	I1104V		Het
Zbtb2	C	T	10: 4,368,986 (GRCm38)	D347N	possibly damaging	Het
Zfyve9	A	T	4: 108,718,256 (GRCm38)	S543T	probably benign	Het
Zhx1	T	C	15: 58,053,296 (GRCm38)	N518S	probably damaging	Het
Zmym6	T	C	4: 127,122,982 (GRCm38)	V852A	possibly damaging	Het

Other mutations in Nav2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01097:Nav2	APN	7	49,571,194 (GRCm38)	missense	probably damaging	1.00
IGL01150:Nav2	APN	7	49,452,521 (GRCm38)	missense	probably benign	0.17
IGL01649:Nav2	APN	7	49,575,729 (GRCm38)	missense	probably damaging	1.00
IGL01662:Nav2	APN	7	49,571,209 (GRCm38)	missense	probably damaging	1.00
IGL02297:Nav2	APN	7	49,594,229 (GRCm38)	missense	probably damaging	0.98
IGL02313:Nav2	APN	7	49,558,773 (GRCm38)	missense	probably damaging	0.99
IGL02441:Nav2	APN	7	49,452,512 (GRCm38)	missense	probably damaging	1.00
IGL02472:Nav2	APN	7	49,546,041 (GRCm38)	missense	probably damaging	1.00
IGL02477:Nav2	APN	7	49,582,875 (GRCm38)	missense	probably damaging	0.99
IGL02725:Nav2	APN	7	49,565,095 (GRCm38)	missense	probably damaging	1.00
IGL02944:Nav2	APN	7	49,420,256 (GRCm38)	missense	probably damaging	0.99
IGL02953:Nav2	APN	7	49,548,423 (GRCm38)	missense	probably damaging	1.00
IGL03105:Nav2	APN	7	49,464,879 (GRCm38)	missense	probably damaging	1.00
IGL03234:Nav2	APN	7	49,462,008 (GRCm38)	missense	possibly damaging	0.94
IGL03274:Nav2	APN	7	49,362,099 (GRCm38)	missense	probably damaging	1.00
IGL03294:Nav2	APN	7	49,491,457 (GRCm38)	nonsense	probably null
R0006:Nav2	UTSW	7	49,453,230 (GRCm38)	missense	possibly damaging	0.50
R0070:Nav2	UTSW	7	49,570,714 (GRCm38)	missense	probably damaging	1.00
R0113:Nav2	UTSW	7	49,535,953 (GRCm38)	missense	probably damaging	1.00
R0306:Nav2	UTSW	7	49,545,903 (GRCm38)	missense	probably benign	0.01
R0346:Nav2	UTSW	7	49,604,585 (GRCm38)	missense	probably benign	0.11
R0539:Nav2	UTSW	7	49,461,938 (GRCm38)	missense	probably damaging	1.00
R0669:Nav2	UTSW	7	49,408,683 (GRCm38)	missense	probably damaging	1.00
R0785:Nav2	UTSW	7	49,420,333 (GRCm38)	missense	probably benign	0.06
R0970:Nav2	UTSW	7	49,584,153 (GRCm38)	missense	probably damaging	1.00
R1162:Nav2	UTSW	7	49,536,040 (GRCm38)	splice site	probably benign
R1274:Nav2	UTSW	7	49,604,430 (GRCm38)	nonsense	probably null
R1463:Nav2	UTSW	7	49,535,962 (GRCm38)	missense	probably damaging	1.00
R1464:Nav2	UTSW	7	49,362,204 (GRCm38)	missense	probably damaging	1.00
R1464:Nav2	UTSW	7	49,362,204 (GRCm38)	missense	probably damaging	1.00
R1536:Nav2	UTSW	7	49,545,934 (GRCm38)	missense	probably damaging	1.00
R1612:Nav2	UTSW	7	49,571,211 (GRCm38)	missense	probably damaging	1.00
R1638:Nav2	UTSW	7	49,452,465 (GRCm38)	missense	probably benign
R1731:Nav2	UTSW	7	49,548,174 (GRCm38)	missense	probably damaging	1.00
R1734:Nav2	UTSW	7	49,575,720 (GRCm38)	missense	probably damaging	1.00
R1865:Nav2	UTSW	7	49,548,195 (GRCm38)	missense	possibly damaging	0.95
R1945:Nav2	UTSW	7	49,464,872 (GRCm38)	missense	probably damaging	1.00
R1997:Nav2	UTSW	7	49,548,471 (GRCm38)	missense	probably benign	0.16
R2061:Nav2	UTSW	7	49,598,897 (GRCm38)	splice site	probably benign
R2117:Nav2	UTSW	7	49,464,580 (GRCm38)	missense	probably benign	0.00
R2174:Nav2	UTSW	7	49,452,663 (GRCm38)	missense	probably damaging	0.99
R2182:Nav2	UTSW	7	49,597,254 (GRCm38)	missense	probably benign	0.38
R2251:Nav2	UTSW	7	49,453,277 (GRCm38)	missense	probably damaging	1.00
R2283:Nav2	UTSW	7	49,491,404 (GRCm38)	missense	probably damaging	1.00
R2343:Nav2	UTSW	7	49,598,817 (GRCm38)	missense	possibly damaging	0.82
R2472:Nav2	UTSW	7	49,408,884 (GRCm38)	missense	probably benign
R2568:Nav2	UTSW	7	49,597,564 (GRCm38)	missense	probably damaging	1.00
R2656:Nav2	UTSW	7	49,545,942 (GRCm38)	missense	probably damaging	1.00
R2964:Nav2	UTSW	7	49,557,032 (GRCm38)	missense	probably damaging	1.00
R2966:Nav2	UTSW	7	49,557,032 (GRCm38)	missense	probably damaging	1.00
R3817:Nav2	UTSW	7	49,464,562 (GRCm38)	missense	probably benign	0.00
R3834:Nav2	UTSW	7	49,545,858 (GRCm38)	missense	possibly damaging	0.91
R4207:Nav2	UTSW	7	49,597,231 (GRCm38)	missense	probably damaging	1.00
R4207:Nav2	UTSW	7	49,572,298 (GRCm38)	splice site	probably null
R4411:Nav2	UTSW	7	49,398,109 (GRCm38)	missense	probably benign	0.37
R4413:Nav2	UTSW	7	49,398,109 (GRCm38)	missense	probably benign	0.37
R4440:Nav2	UTSW	7	49,575,263 (GRCm38)	splice site	probably benign
R4440:Nav2	UTSW	7	49,552,037 (GRCm38)	missense	possibly damaging	0.86
R4454:Nav2	UTSW	7	49,548,544 (GRCm38)	splice site	probably null
R4729:Nav2	UTSW	7	49,452,819 (GRCm38)	missense	probably benign	0.17
R4801:Nav2	UTSW	7	49,545,852 (GRCm38)	missense	possibly damaging	0.94
R4802:Nav2	UTSW	7	49,545,852 (GRCm38)	missense	possibly damaging	0.94
R4824:Nav2	UTSW	7	49,409,001 (GRCm38)	intron	probably benign
R4887:Nav2	UTSW	7	49,548,434 (GRCm38)	nonsense	probably null
R4908:Nav2	UTSW	7	49,604,510 (GRCm38)	missense	probably damaging	1.00
R4952:Nav2	UTSW	7	49,304,540 (GRCm38)	intron	probably benign
R4965:Nav2	UTSW	7	49,552,877 (GRCm38)	nonsense	probably null
R5169:Nav2	UTSW	7	49,548,483 (GRCm38)	nonsense	probably null
R5224:Nav2	UTSW	7	49,551,725 (GRCm38)	missense	probably benign	0.00
R5249:Nav2	UTSW	7	49,535,913 (GRCm38)	missense	probably damaging	1.00
R5285:Nav2	UTSW	7	49,548,234 (GRCm38)	missense	probably damaging	1.00
R5314:Nav2	UTSW	7	49,408,692 (GRCm38)	small deletion	probably benign
R5320:Nav2	UTSW	7	49,491,373 (GRCm38)	missense	probably benign	0.00
R5377:Nav2	UTSW	7	49,589,160 (GRCm38)	missense	probably benign	0.02
R5471:Nav2	UTSW	7	49,548,169 (GRCm38)	missense	probably damaging	1.00
R5754:Nav2	UTSW	7	49,557,046 (GRCm38)	missense	probably damaging	1.00
R5832:Nav2	UTSW	7	49,548,069 (GRCm38)	splice site	probably null
R5884:Nav2	UTSW	7	49,597,169 (GRCm38)	nonsense	probably null
R5921:Nav2	UTSW	7	49,304,576 (GRCm38)	intron	probably benign
R6180:Nav2	UTSW	7	49,458,167 (GRCm38)	missense	probably benign	0.39
R6208:Nav2	UTSW	7	49,564,103 (GRCm38)	missense	probably damaging	0.99
R6373:Nav2	UTSW	7	49,453,175 (GRCm38)	missense	probably damaging	1.00
R6450:Nav2	UTSW	7	49,594,366 (GRCm38)	missense	probably damaging	1.00
R6522:Nav2	UTSW	7	49,597,533 (GRCm38)	missense	probably damaging	1.00
R6626:Nav2	UTSW	7	49,594,352 (GRCm38)	missense	probably damaging	1.00
R6695:Nav2	UTSW	7	49,464,904 (GRCm38)	missense	probably benign	0.04
R6705:Nav2	UTSW	7	49,551,916 (GRCm38)	missense	probably damaging	1.00
R6842:Nav2	UTSW	7	49,458,169 (GRCm38)	missense	possibly damaging	0.91
R6847:Nav2	UTSW	7	49,491,456 (GRCm38)	missense	probably benign	0.14
R7312:Nav2	UTSW	7	49,461,924 (GRCm38)	missense	possibly damaging	0.55
R7315:Nav2	UTSW	7	49,548,289 (GRCm38)	missense	possibly damaging	0.61
R7337:Nav2	UTSW	7	49,551,773 (GRCm38)	missense	possibly damaging	0.56
R7366:Nav2	UTSW	7	49,554,203 (GRCm38)	splice site	probably null
R7451:Nav2	UTSW	7	49,552,829 (GRCm38)	splice site	probably null
R7545:Nav2	UTSW	7	49,582,857 (GRCm38)	missense	probably damaging	1.00
R7706:Nav2	UTSW	7	49,594,319 (GRCm38)	missense	probably benign	0.35
R7730:Nav2	UTSW	7	49,572,397 (GRCm38)	missense	probably damaging	1.00
R7812:Nav2	UTSW	7	49,597,173 (GRCm38)	missense	probably benign	0.13
R8097:Nav2	UTSW	7	49,587,777 (GRCm38)	missense	probably damaging	1.00
R8110:Nav2	UTSW	7	49,551,950 (GRCm38)	nonsense	probably null
R8119:Nav2	UTSW	7	49,453,484 (GRCm38)	missense	probably damaging	0.99
R8298:Nav2	UTSW	7	49,554,261 (GRCm38)	critical splice donor site	probably null
R8306:Nav2	UTSW	7	49,546,017 (GRCm38)	missense	probably benign	0.33
R8331:Nav2	UTSW	7	49,452,623 (GRCm38)	missense	probably benign
R8402:Nav2	UTSW	7	49,453,437 (GRCm38)	missense	probably benign	0.43
R8421:Nav2	UTSW	7	49,452,521 (GRCm38)	missense	probably benign
R8478:Nav2	UTSW	7	49,461,985 (GRCm38)	missense	probably damaging	0.99
R8724:Nav2	UTSW	7	49,491,436 (GRCm38)	missense	possibly damaging	0.82
R8753:Nav2	UTSW	7	49,452,572 (GRCm38)	missense	probably benign
R8835:Nav2	UTSW	7	49,598,803 (GRCm38)	missense	possibly damaging	0.83
R8933:Nav2	UTSW	7	49,461,957 (GRCm38)	missense	probably damaging	1.00
R8957:Nav2	UTSW	7	49,571,216 (GRCm38)	missense	probably damaging	1.00
R9069:Nav2	UTSW	7	49,558,813 (GRCm38)	missense	probably damaging	0.99
R9095:Nav2	UTSW	7	49,604,545 (GRCm38)	missense	probably damaging	1.00
R9223:Nav2	UTSW	7	49,552,851 (GRCm38)	missense	probably damaging	1.00
R9261:Nav2	UTSW	7	49,597,156 (GRCm38)	missense	probably damaging	1.00
X0023:Nav2	UTSW	7	49,547,899 (GRCm38)	missense	possibly damaging	0.47
Z1177:Nav2	UTSW	7	49,594,223 (GRCm38)	missense	probably benign	0.01
Z1177:Nav2	UTSW	7	49,452,761 (GRCm38)	missense	possibly damaging	0.47

Predicted Primers

PCR Primer
(F):5'- CCTAAGACTGACTGCATTACTCTC -3'
(R):5'- TGTAGCAACGCTTTCCCCAC -3'

Sequencing Primer
(F):5'- AAGACTGACTGCATTACTCTCTTGTC -3'
(R):5'- CACTGTGCTAATGTCATTGACGAC -3'

Posted On

2019-06-26