Incidental Mutation 'R7289:Sez6'
| ID |
566256 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sez6
|
| Ensembl Gene |
ENSMUSG00000000632 |
| Gene Name |
seizure related gene 6 |
| Synonyms |
sez-6, D11Bhm177e |
| MMRRC Submission |
045396-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7289 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
77821626-77869874 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 77865149 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 632
(I632N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091532
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000000646]
[ENSMUST00000093995]
|
| AlphaFold |
Q7TSK2 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000000646
AA Change: I632N
PolyPhen 2
Score 0.917 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000000646
Gene: ENSMUSG00000000632
AA Change: I632N
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
72 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
223 |
235 |
N/A |
INTRINSIC |
|
CUB
|
241 |
350 |
9.36e-2 |
SMART |
|
CCP
|
354 |
409 |
1.23e-10 |
SMART |
|
CUB
|
413 |
524 |
1.41e-28 |
SMART |
|
CCP
|
529 |
586 |
5.43e-12 |
SMART |
|
CUB
|
590 |
701 |
7.49e-24 |
SMART |
|
CCP
|
707 |
762 |
3.09e-16 |
SMART |
|
CCP
|
768 |
827 |
3.5e-15 |
SMART |
|
CCP
|
835 |
892 |
1.42e-15 |
SMART |
|
transmembrane domain
|
910 |
932 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000093995
AA Change: I632N
PolyPhen 2
Score 0.956 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000091532
Gene: ENSMUSG00000000632
AA Change: I632N
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
72 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
223 |
235 |
N/A |
INTRINSIC |
|
CUB
|
241 |
350 |
9.36e-2 |
SMART |
|
CCP
|
354 |
409 |
1.23e-10 |
SMART |
|
CUB
|
413 |
524 |
1.41e-28 |
SMART |
|
CCP
|
529 |
586 |
5.43e-12 |
SMART |
|
CUB
|
590 |
701 |
7.49e-24 |
SMART |
|
CCP
|
707 |
762 |
3.09e-16 |
SMART |
|
CCP
|
768 |
827 |
3.5e-15 |
SMART |
|
CCP
|
835 |
892 |
1.42e-15 |
SMART |
|
transmembrane domain
|
923 |
945 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000115660
Gene: ENSMUSG00000000632
AA Change: I259N
| Domain | Start | End | E-Value | Type |
|---|
|
CUB
|
29 |
140 |
9.8e-28 |
SMART |
|
CCP
|
157 |
214 |
5.43e-12 |
SMART |
|
Pfam:CUB
|
218 |
278 |
1.6e-11 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000151982
AA Change: S447T
PolyPhen 2
Score 0.528 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000132041
Gene: ENSMUSG00000000632
AA Change: S447T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
57 |
69 |
N/A |
INTRINSIC |
|
CUB
|
75 |
184 |
9.36e-2 |
SMART |
|
CCP
|
188 |
243 |
1.23e-10 |
SMART |
|
CUB
|
247 |
358 |
8.08e-29 |
SMART |
|
low complexity region
|
379 |
394 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is thought to contain five cysteine-rich motifs that are similar to sushi domains, as well as two domains similar to the amino terminal half of the CUB (for complement C1r/C1s, Uegf, Bmp1) domain. Mutations in this gene have been associated with febrile seizures. [provided by RefSeq, Jul 2016]
PHENOTYPE: Mice homozygous for a null allele exhibit increased short dendrites, decreased excitatory synaptic signaling, resistance to pharmacologically induces seizures, decreased activity and impaired learning and coordination. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aars2 |
G |
A |
17: 45,818,550 (GRCm39) |
D112N |
probably damaging |
Het |
| Abca7 |
T |
A |
10: 79,845,778 (GRCm39) |
I1580K |
probably damaging |
Het |
| Aebp1 |
A |
G |
11: 5,815,059 (GRCm39) |
D234G |
probably damaging |
Het |
| Agap1 |
T |
A |
1: 89,383,153 (GRCm39) |
M1K |
probably null |
Het |
| Agrn |
A |
T |
4: 156,263,389 (GRCm39) |
L345H |
probably damaging |
Het |
| Amfr |
A |
G |
8: 94,725,754 (GRCm39) |
M209T |
possibly damaging |
Het |
| Angel2 |
G |
A |
1: 190,673,371 (GRCm39) |
R338H |
possibly damaging |
Het |
| Ankrd27 |
C |
T |
7: 35,330,674 (GRCm39) |
A866V |
probably damaging |
Het |
| Apc |
G |
A |
18: 34,448,324 (GRCm39) |
R1740Q |
probably damaging |
Het |
| Arhgap32 |
A |
T |
9: 32,168,233 (GRCm39) |
S739C |
possibly damaging |
Het |
| Arhgap32 |
G |
C |
9: 32,168,234 (GRCm39) |
S739T |
probably benign |
Het |
| Arhgef2 |
C |
T |
3: 88,543,192 (GRCm39) |
S418L |
probably benign |
Het |
| Arhgef25 |
T |
C |
10: 127,019,641 (GRCm39) |
T472A |
possibly damaging |
Het |
| Atrnl1 |
C |
T |
19: 57,638,846 (GRCm39) |
S328F |
probably benign |
Het |
| Bahcc1 |
C |
T |
11: 120,171,000 (GRCm39) |
A1514V |
probably benign |
Het |
| Calcoco2 |
C |
T |
11: 95,990,823 (GRCm39) |
E305K |
unknown |
Het |
| Ccn1 |
C |
T |
3: 145,354,428 (GRCm39) |
W161* |
probably null |
Het |
| Cdc42bpa |
A |
T |
1: 179,889,362 (GRCm39) |
K203* |
probably null |
Het |
| Cmc1 |
A |
T |
9: 117,904,250 (GRCm39) |
I47N |
possibly damaging |
Het |
| Cntln |
A |
G |
4: 84,964,540 (GRCm39) |
E656G |
possibly damaging |
Het |
| Dcun1d3 |
T |
C |
7: 119,458,864 (GRCm39) |
K57R |
possibly damaging |
Het |
| Ddx23 |
T |
C |
15: 98,546,492 (GRCm39) |
E559G |
probably damaging |
Het |
| Dennd6a |
G |
A |
14: 26,333,193 (GRCm39) |
R367Q |
probably damaging |
Het |
| Desi2 |
A |
T |
1: 178,083,702 (GRCm39) |
|
probably benign |
Het |
| Dido1 |
T |
C |
2: 180,301,424 (GRCm39) |
D2160G |
unknown |
Het |
| Efcab3 |
T |
C |
11: 104,929,184 (GRCm39) |
M4838T |
probably benign |
Het |
| Epb41 |
A |
G |
4: 131,718,520 (GRCm39) |
|
probably null |
Het |
| Esrrb |
T |
A |
12: 86,517,331 (GRCm39) |
|
probably null |
Het |
| Fabp1 |
C |
A |
6: 71,180,111 (GRCm39) |
T94N |
probably benign |
Het |
| Fam120a |
A |
T |
13: 49,045,482 (GRCm39) |
C785S |
probably damaging |
Het |
| Fam243 |
T |
C |
16: 92,117,710 (GRCm39) |
I193V |
probably damaging |
Het |
| Foxc1 |
A |
G |
13: 31,991,243 (GRCm39) |
Y18C |
probably damaging |
Het |
| Fshr |
T |
C |
17: 89,293,272 (GRCm39) |
T469A |
probably benign |
Het |
| Gm14399 |
T |
A |
2: 174,972,204 (GRCm39) |
H517L |
unknown |
Het |
| Gm39115 |
G |
T |
7: 141,689,297 (GRCm39) |
Q159K |
unknown |
Het |
| Gm7347 |
T |
A |
5: 26,262,306 (GRCm39) |
I72F |
possibly damaging |
Het |
| Hmcn1 |
A |
G |
1: 150,559,466 (GRCm39) |
V2395A |
possibly damaging |
Het |
| Ighv5-17 |
T |
G |
12: 113,822,858 (GRCm39) |
T88P |
probably damaging |
Het |
| Insm2 |
T |
A |
12: 55,647,329 (GRCm39) |
Y358N |
probably damaging |
Het |
| Kazn |
A |
T |
4: 141,844,486 (GRCm39) |
L409Q |
|
Het |
| Kcnj5 |
A |
C |
9: 32,234,045 (GRCm39) |
L90R |
probably damaging |
Het |
| Kcnv2 |
A |
T |
19: 27,311,084 (GRCm39) |
T484S |
probably damaging |
Het |
| Kdm3b |
T |
C |
18: 34,927,557 (GRCm39) |
Y140H |
probably benign |
Het |
| Kifbp |
A |
C |
10: 62,401,895 (GRCm39) |
C261W |
probably damaging |
Het |
| Krt25 |
C |
T |
11: 99,212,098 (GRCm39) |
A180T |
probably benign |
Het |
| Mmp1a |
A |
G |
9: 7,467,294 (GRCm39) |
E290G |
probably damaging |
Het |
| Muc21 |
G |
A |
17: 35,929,761 (GRCm39) |
A1475V |
unknown |
Het |
| Nr3c1 |
T |
C |
18: 39,547,654 (GRCm39) |
T755A |
probably benign |
Het |
| Nr3c1 |
A |
T |
18: 39,555,786 (GRCm39) |
I517N |
probably benign |
Het |
| Nxpe2 |
A |
G |
9: 48,234,339 (GRCm39) |
|
probably null |
Het |
| Oaz1 |
C |
A |
10: 80,662,673 (GRCm39) |
T27K |
possibly damaging |
Het |
| Or4p7 |
A |
T |
2: 88,222,050 (GRCm39) |
H153L |
probably damaging |
Het |
| Or51f5 |
T |
C |
7: 102,424,634 (GRCm39) |
I301T |
probably damaging |
Het |
| Or5t5 |
G |
T |
2: 86,617,034 (GRCm39) |
C320F |
probably benign |
Het |
| Or6z3 |
T |
A |
7: 6,463,777 (GRCm39) |
W90R |
probably benign |
Het |
| Or8k21 |
A |
G |
2: 86,145,369 (GRCm39) |
M87T |
probably benign |
Het |
| Or8s5 |
A |
G |
15: 98,237,943 (GRCm39) |
V309A |
probably damaging |
Het |
| Pafah2 |
A |
T |
4: 134,147,308 (GRCm39) |
K319M |
probably damaging |
Het |
| Pask |
A |
T |
1: 93,259,309 (GRCm39) |
V236E |
probably damaging |
Het |
| Pcdh1 |
T |
C |
18: 38,322,966 (GRCm39) |
T956A |
probably damaging |
Het |
| Pcdhb18 |
C |
A |
18: 37,623,700 (GRCm39) |
N343K |
probably damaging |
Het |
| Pcsk2 |
A |
T |
2: 143,532,343 (GRCm39) |
I164F |
probably damaging |
Het |
| Phf1 |
T |
C |
17: 27,154,289 (GRCm39) |
Y169H |
probably damaging |
Het |
| Pkdrej |
T |
A |
15: 85,705,301 (GRCm39) |
I212F |
probably benign |
Het |
| Pnkp |
T |
A |
7: 44,508,114 (GRCm39) |
W146R |
probably damaging |
Het |
| Prkcb |
A |
T |
7: 122,143,910 (GRCm39) |
I325F |
probably benign |
Het |
| Ptpn21 |
C |
T |
12: 98,670,450 (GRCm39) |
D239N |
probably benign |
Het |
| Ptprb |
A |
G |
10: 116,164,070 (GRCm39) |
T626A |
probably damaging |
Het |
| Pttg1 |
T |
C |
11: 43,311,916 (GRCm39) |
N180D |
probably benign |
Het |
| Raly |
G |
A |
2: 154,703,774 (GRCm39) |
R115Q |
probably damaging |
Het |
| Rims2 |
A |
T |
15: 39,301,114 (GRCm39) |
M474L |
probably benign |
Het |
| Sash1 |
A |
T |
10: 8,605,960 (GRCm39) |
I810N |
probably damaging |
Het |
| Scnn1g |
T |
A |
7: 121,337,304 (GRCm39) |
L55* |
probably null |
Het |
| Sema6b |
A |
T |
17: 56,432,573 (GRCm39) |
D543E |
possibly damaging |
Het |
| Serpina11 |
C |
T |
12: 103,952,761 (GRCm39) |
G5E |
unknown |
Het |
| Sesn3 |
A |
T |
9: 14,187,848 (GRCm39) |
M1L |
probably benign |
Het |
| Sgo2b |
A |
T |
8: 64,394,192 (GRCm39) |
I49N |
probably damaging |
Het |
| Slc30a2 |
A |
T |
4: 134,071,524 (GRCm39) |
I86F |
possibly damaging |
Het |
| Slc38a6 |
T |
A |
12: 73,333,786 (GRCm39) |
W30R |
probably benign |
Het |
| Spata31g1 |
A |
T |
4: 42,972,379 (GRCm39) |
T571S |
probably benign |
Het |
| Spata31g1 |
A |
T |
4: 42,973,252 (GRCm39) |
I862F |
possibly damaging |
Het |
| Stk31 |
T |
G |
6: 49,415,393 (GRCm39) |
V576G |
probably benign |
Het |
| Szt2 |
G |
A |
4: 118,233,075 (GRCm39) |
T2297I |
unknown |
Het |
| Tmem208 |
T |
C |
8: 106,061,418 (GRCm39) |
F148S |
possibly damaging |
Het |
| Tprg1l |
A |
G |
4: 154,245,031 (GRCm39) |
L19P |
possibly damaging |
Het |
| Tubg2 |
C |
A |
11: 101,050,897 (GRCm39) |
N207K |
probably damaging |
Het |
| Ube2n |
G |
T |
10: 95,377,612 (GRCm39) |
K130N |
probably benign |
Het |
| Usp36 |
T |
C |
11: 118,164,355 (GRCm39) |
Y384C |
probably damaging |
Het |
| Vcan |
A |
T |
13: 89,840,852 (GRCm39) |
L1564* |
probably null |
Het |
| Xkr6 |
A |
T |
14: 64,035,748 (GRCm39) |
D283V |
unknown |
Het |
| Zfp654 |
T |
C |
16: 64,605,523 (GRCm39) |
H352R |
probably benign |
Het |
| Zfp819 |
T |
A |
7: 43,266,506 (GRCm39) |
C330S |
probably damaging |
Het |
| Zfp970 |
G |
T |
2: 177,167,086 (GRCm39) |
C220F |
probably damaging |
Het |
|
| Other mutations in Sez6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01125:Sez6
|
APN |
11 |
77,868,115 (GRCm39) |
splice site |
probably benign |
|
|
IGL01142:Sez6
|
APN |
11 |
77,864,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02252:Sez6
|
APN |
11 |
77,865,339 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02332:Sez6
|
APN |
11 |
77,845,568 (GRCm39) |
splice site |
probably benign |
|
|
IGL02366:Sez6
|
APN |
11 |
77,867,708 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02479:Sez6
|
APN |
11 |
77,868,852 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL02963:Sez6
|
APN |
11 |
77,853,775 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
velum
|
UTSW |
11 |
77,865,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0054:Sez6
|
UTSW |
11 |
77,844,699 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0054:Sez6
|
UTSW |
11 |
77,844,699 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0089:Sez6
|
UTSW |
11 |
77,865,170 (GRCm39) |
splice site |
probably benign |
|
|
R0485:Sez6
|
UTSW |
11 |
77,844,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0598:Sez6
|
UTSW |
11 |
77,868,647 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R0729:Sez6
|
UTSW |
11 |
77,867,411 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1117:Sez6
|
UTSW |
11 |
77,865,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1199:Sez6
|
UTSW |
11 |
77,844,711 (GRCm39) |
missense |
probably benign |
|
|
R1534:Sez6
|
UTSW |
11 |
77,853,871 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1835:Sez6
|
UTSW |
11 |
77,844,329 (GRCm39) |
missense |
probably benign |
|
|
R1840:Sez6
|
UTSW |
11 |
77,844,543 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1929:Sez6
|
UTSW |
11 |
77,863,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1970:Sez6
|
UTSW |
11 |
77,844,894 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3156:Sez6
|
UTSW |
11 |
77,844,605 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R3930:Sez6
|
UTSW |
11 |
77,867,708 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3931:Sez6
|
UTSW |
11 |
77,867,708 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4894:Sez6
|
UTSW |
11 |
77,866,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4904:Sez6
|
UTSW |
11 |
77,866,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5026:Sez6
|
UTSW |
11 |
77,859,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5040:Sez6
|
UTSW |
11 |
77,859,915 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5057:Sez6
|
UTSW |
11 |
77,863,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5093:Sez6
|
UTSW |
11 |
77,867,388 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5640:Sez6
|
UTSW |
11 |
77,864,585 (GRCm39) |
intron |
probably benign |
|
|
R6013:Sez6
|
UTSW |
11 |
77,864,623 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6126:Sez6
|
UTSW |
11 |
77,864,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6153:Sez6
|
UTSW |
11 |
77,868,648 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6279:Sez6
|
UTSW |
11 |
77,867,367 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6300:Sez6
|
UTSW |
11 |
77,867,367 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6475:Sez6
|
UTSW |
11 |
77,864,670 (GRCm39) |
|
|
|
|
R6722:Sez6
|
UTSW |
11 |
77,844,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6897:Sez6
|
UTSW |
11 |
77,844,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6910:Sez6
|
UTSW |
11 |
77,844,695 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7012:Sez6
|
UTSW |
11 |
77,868,621 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7233:Sez6
|
UTSW |
11 |
77,863,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7265:Sez6
|
UTSW |
11 |
77,853,691 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7405:Sez6
|
UTSW |
11 |
77,853,717 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7408:Sez6
|
UTSW |
11 |
77,844,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7485:Sez6
|
UTSW |
11 |
77,864,711 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7592:Sez6
|
UTSW |
11 |
77,868,876 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7778:Sez6
|
UTSW |
11 |
77,865,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7793:Sez6
|
UTSW |
11 |
77,868,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7818:Sez6
|
UTSW |
11 |
77,867,728 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7824:Sez6
|
UTSW |
11 |
77,865,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7980:Sez6
|
UTSW |
11 |
77,844,668 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8008:Sez6
|
UTSW |
11 |
77,864,082 (GRCm39) |
nonsense |
probably null |
|
|
R8840:Sez6
|
UTSW |
11 |
77,867,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8947:Sez6
|
UTSW |
11 |
77,844,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8973:Sez6
|
UTSW |
11 |
77,865,397 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9040:Sez6
|
UTSW |
11 |
77,864,762 (GRCm39) |
missense |
probably benign |
|
|
R9081:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9082:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9092:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9094:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9095:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9097:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9169:Sez6
|
UTSW |
11 |
77,868,473 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9513:Sez6
|
UTSW |
11 |
77,865,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9630:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9632:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9646:Sez6
|
UTSW |
11 |
77,867,632 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9709:Sez6
|
UTSW |
11 |
77,865,121 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
X0013:Sez6
|
UTSW |
11 |
77,845,606 (GRCm39) |
missense |
probably benign |
0.01 |
|
X0067:Sez6
|
UTSW |
11 |
77,865,264 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1088:Sez6
|
UTSW |
11 |
77,864,023 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCATATTGGAGAGGATGCGC -3'
(R):5'- AAGAGCTTGAAGTGGCCAC -3'
Sequencing Primer
(F):5'- TGGTGCTCTCTCCAAACT -3'
(R):5'- TGAGTATTGGCCCAGGACC -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation