Mutagenetix > Incidental Mutation

Incidental Mutation 'R7291:Cul9'

566452

Institutional Source

Beutler Lab

Gene Symbol

Cul9

Ensembl Gene

ENSMUSG00000040327

Gene Name

cullin 9

Synonyms

1810035I07Rik, Parc

MMRRC Submission

045322-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.294) question?

Stock #

R7291 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

46500572-46546388 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 46540433 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Isoleucine at position 354 (V354I)

Ref Sequence

ENSEMBL: ENSMUSP00000138418 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000066026] [ENSMUST00000182485]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000066026
AA Change: V354I

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)

SMART Domains

Protein: ENSMUSP00000067736
Gene: ENSMUSG00000040327
AA Change: V354I

Domain	Start	End	E-Value	Type
low complexity region	46	61	N/A	INTRINSIC
low complexity region	119	131	N/A	INTRINSIC
low complexity region	345	357	N/A	INTRINSIC
Pfam:Cul7	367	441	1e-35	PFAM
low complexity region	447	460	N/A	INTRINSIC
low complexity region	525	540	N/A	INTRINSIC
low complexity region	845	860	N/A	INTRINSIC
low complexity region	873	880	N/A	INTRINSIC
APC10	1166	1325	1.97e-56	SMART
low complexity region	1437	1450	N/A	INTRINSIC
low complexity region	1563	1578	N/A	INTRINSIC
low complexity region	1646	1671	N/A	INTRINSIC
Cullin_Nedd8	1867	1950	7.55e-6	SMART
Blast:RING	2074	2122	2e-13	BLAST
IBR	2144	2207	8.99e-14	SMART
IBR	2228	2283	4.66e-2	SMART
low complexity region	2503	2520	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000182485
AA Change: V354I

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)

SMART Domains

Protein: ENSMUSP00000138418
Gene: ENSMUSG00000040327
AA Change: V354I

Domain	Start	End	E-Value	Type
low complexity region	46	61	N/A	INTRINSIC
low complexity region	119	131	N/A	INTRINSIC
low complexity region	345	357	N/A	INTRINSIC
Pfam:Cul7	367	442	1.4e-33	PFAM
low complexity region	447	460	N/A	INTRINSIC
low complexity region	525	540	N/A	INTRINSIC
low complexity region	845	860	N/A	INTRINSIC
low complexity region	873	880	N/A	INTRINSIC
APC10	1166	1325	1.97e-56	SMART
low complexity region	1437	1450	N/A	INTRINSIC
low complexity region	1563	1578	N/A	INTRINSIC
low complexity region	1646	1671	N/A	INTRINSIC
Cullin_Nedd8	1867	1950	7.55e-6	SMART
Blast:RING	2074	2122	3e-13	BLAST
IBR	2144	2207	8.99e-14	SMART
IBR	2228	2283	4.66e-2	SMART
coiled coil region	2461	2497	N/A	INTRINSIC
low complexity region	2513	2530	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.6%

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased body weight, increased incidence of tumors, and decreased cellular sensitivity to radiation-induced apoptosis. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 83 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
9430069I07Rik	T	C	15: 34,355,553 (GRCm38)	E51G	possibly damaging	Het
9530053A07Rik	A	C	7: 28,140,220 (GRCm38)	D486A	probably benign	Het
Abca14	C	A	7: 120,289,609 (GRCm38)	C1259*	probably null	Het
Ablim1	T	C	19: 57,215,908 (GRCm38)	E17G	probably benign	Het
Acsf3	G	A	8: 122,813,577 (GRCm38)	V505I	probably benign	Het
Actn1	T	C	12: 80,174,085 (GRCm38)	M650V	probably benign	Het
Adamts4	G	A	1: 171,256,528 (GRCm38)	V525I	probably benign	Het
Adh1	T	C	3: 138,282,808 (GRCm38)	Y181H	probably damaging	Het
Alpl	G	A	4: 137,752,698 (GRCm38)	R168W	probably damaging	Het
Ate1	T	G	7: 130,519,931 (GRCm38)	K11Q	probably benign	Het
Atpaf1	T	A	4: 115,811,091 (GRCm38)	F314L	probably damaging	Het
Baiap3	T	A	17: 25,244,317 (GRCm38)	D1004V	probably damaging	Het
Bpifb9a	C	T	2: 154,267,696 (GRCm38)	T504M	probably damaging	Het
C1s2	T	A	6: 124,625,384 (GRCm38)	I623F	probably benign	Het
Card11	T	C	5: 140,901,070 (GRCm38)	D308G	probably damaging	Het
Dnah1	A	T	14: 31,298,705 (GRCm38)	F1236I	probably damaging	Het
Dync2h1	T	A	9: 6,929,590 (GRCm38)	I4266F	possibly damaging	Het
Ear10	A	T	14: 43,922,920 (GRCm38)	V150D	probably damaging	Het
Elfn2	C	T	15: 78,672,983 (GRCm38)	A455T	probably benign	Het
Erp44	A	G	4: 48,208,792 (GRCm38)	Y223H	probably damaging	Het
Fam110b	T	A	4: 5,798,895 (GRCm38)	H104Q	probably benign	Het
Fcgbp	A	G	7: 28,101,392 (GRCm38)	N1288D	probably benign	Het
Fcrl1	T	C	3: 87,385,781 (GRCm38)		probably null	Het
Fmo2	G	T	1: 162,887,702 (GRCm38)	P117Q	probably benign	Het
Fsip2	A	G	2: 82,980,519 (GRCm38)	K2394R	possibly damaging	Het
Gab1	T	G	8: 80,800,151 (GRCm38)	K106T	probably damaging	Het
Gatad2b	T	C	3: 90,351,414 (GRCm38)	V248A	probably damaging	Het
Gemin6	T	C	17: 80,227,775 (GRCm38)	S55P	possibly damaging	Het
Gfm2	G	A	13: 97,175,024 (GRCm38)	V701I	probably benign	Het
Gm3250	T	C	10: 77,782,227 (GRCm38)	T106A	unknown	Het
Gm7356	T	C	17: 14,001,581 (GRCm38)	N62S	probably benign	Het
Gsdmc4	T	C	15: 63,902,840 (GRCm38)	T31A	possibly damaging	Het
H2-M10.1	T	A	17: 36,325,729 (GRCm38)	D61V	probably damaging	Het
Heatr5a	A	G	12: 51,925,339 (GRCm38)	L716S	probably damaging	Het
Hecw2	A	G	1: 53,914,594 (GRCm38)	Y831H	probably damaging	Het
Ifi202b	C	T	1: 173,974,815 (GRCm38)	S151N	probably benign	Het
Il15ra	C	T	2: 11,718,381 (GRCm38)	T72I	probably damaging	Het
Ints1	A	G	5: 139,765,074 (GRCm38)	L858P	probably damaging	Het
Kat2a	C	T	11: 100,710,900 (GRCm38)	V230I	possibly damaging	Het
Kcnq2	A	T	2: 181,088,379 (GRCm38)	I498N	possibly damaging	Het
Kif26b	C	T	1: 178,679,046 (GRCm38)	T229I	possibly damaging	Het
Ly75	T	A	2: 60,329,993 (GRCm38)	I957F	probably damaging	Het
Map3k12	T	A	15: 102,502,166 (GRCm38)	R459W	probably damaging	Het
Mia2	T	A	12: 59,158,369 (GRCm38)		probably null	Het
Mrgprf	A	G	7: 145,307,469 (GRCm38)	I53V	unknown	Het
Mttp	A	G	3: 138,091,203 (GRCm38)	L846P	probably damaging	Het
Myrip	C	T	9: 120,417,141 (GRCm38)	L112F	probably damaging	Het
Nav1	A	G	1: 135,465,859 (GRCm38)	F1047S	probably damaging	Het
Nfkbib	T	C	7: 28,759,203 (GRCm38)	D327G	possibly damaging	Het
Notch1	C	T	2: 26,476,375 (GRCm38)	V776I	probably benign	Het
Obsl1	G	T	1: 75,489,517 (GRCm38)	D1522E	probably damaging	Het
Olfr1464-ps1	A	T	19: 13,282,153 (GRCm38)	F302I	unknown	Het
Olfr605	T	A	7: 103,442,788 (GRCm38)	M112L	probably benign	Het
Olfr823	T	C	10: 130,112,224 (GRCm38)	K189E	probably benign	Het
Olfr859	T	C	9: 19,808,648 (GRCm38)	M110T	possibly damaging	Het
Pde7a	T	C	3: 19,227,674 (GRCm38)	N471D	probably benign	Het
Pla2r1	T	C	2: 60,530,435 (GRCm38)	H203R	probably benign	Het
Plch2	C	A	4: 154,998,472 (GRCm38)	C573F	probably damaging	Het
Polr1a	G	A	6: 71,941,456 (GRCm38)	R666Q	probably benign	Het
Prepl	T	C	17: 85,081,240 (GRCm38)	N145S	probably benign	Het
Psen2	C	T	1: 180,238,956 (GRCm38)	V139M	probably benign	Het
Ptgdr	A	T	14: 44,859,192 (GRCm38)	M21K	possibly damaging	Het
Rapgef6	T	C	11: 54,691,239 (GRCm38)	W1331R	probably benign	Het
Rp1l1	G	A	14: 64,032,298 (GRCm38)	G1778S	probably benign	Het
Rrbp1	A	T	2: 143,969,462 (GRCm38)	M824K	probably benign	Het
Sel1l	T	C	12: 91,848,965 (GRCm38)	T23A	probably benign	Het
Sele	A	G	1: 164,053,868 (GRCm38)	S515G	possibly damaging	Het
Slc22a23	T	C	13: 34,197,839 (GRCm38)	N421D	probably damaging	Het
Slc35f3	T	G	8: 126,394,558 (GRCm38)	L386R	probably benign	Het
Stab2	G	A	10: 86,946,220 (GRCm38)	S699L	probably damaging	Het
Synrg	A	T	11: 84,009,381 (GRCm38)	L726F	probably damaging	Het
Syt3	G	A	7: 44,395,919 (GRCm38)	V528M	probably damaging	Het
Szt2	A	G	4: 118,391,249 (GRCm38)	I655T	probably damaging	Het
Tbr1	T	C	2: 61,812,256 (GRCm38)	S622P	probably damaging	Het
Tex36	C	T	7: 133,587,223 (GRCm38)	G207S	probably benign	Het
Trav5n-4	G	A	14: 53,312,942 (GRCm38)	W13*	probably null	Het
Trdn	A	T	10: 33,437,736 (GRCm38)	E500V	probably null	Het
Ugt2b38	A	T	5: 87,411,895 (GRCm38)	N379K	probably damaging	Het
Unc13d	T	C	11: 116,074,050 (GRCm38)	R248G	possibly damaging	Het
Vmn1r195	C	T	13: 22,278,749 (GRCm38)	L130F	probably damaging	Het
Vmn2r110	T	C	17: 20,574,209 (GRCm38)	I733V	probably benign	Het
Zfp870	T	A	17: 32,883,854 (GRCm38)	N167I	probably damaging	Het
Zmynd10	A	T	9: 107,549,304 (GRCm38)	M179L	probably benign	Het

Other mutations in Cul9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00087:Cul9	APN	17	46,525,709 (GRCm38)	missense	probably damaging	1.00
IGL00330:Cul9	APN	17	46,510,841 (GRCm38)	splice site	probably benign
IGL00726:Cul9	APN	17	46,528,096 (GRCm38)	missense	probably damaging	1.00
IGL01020:Cul9	APN	17	46,539,023 (GRCm38)	missense	probably damaging	1.00
IGL01358:Cul9	APN	17	46,538,314 (GRCm38)	missense	probably damaging	1.00
IGL01410:Cul9	APN	17	46,528,646 (GRCm38)	missense	probably damaging	0.99
IGL01781:Cul9	APN	17	46,539,304 (GRCm38)	missense	probably benign
IGL01873:Cul9	APN	17	46,502,452 (GRCm38)	missense	probably damaging	0.99
IGL02117:Cul9	APN	17	46,540,375 (GRCm38)	missense	probably benign	0.00
IGL02300:Cul9	APN	17	46,521,032 (GRCm38)	splice site	probably benign
IGL02426:Cul9	APN	17	46,523,258 (GRCm38)	missense	possibly damaging	0.95
IGL02427:Cul9	APN	17	46,502,632 (GRCm38)	missense	possibly damaging	0.69
IGL02496:Cul9	APN	17	46,540,376 (GRCm38)	missense	possibly damaging	0.72
IGL03008:Cul9	APN	17	46,502,697 (GRCm38)	splice site	probably benign
IGL03059:Cul9	APN	17	46,538,987 (GRCm38)	missense	probably damaging	0.98
IGL03302:Cul9	APN	17	46,526,640 (GRCm38)	missense	probably damaging	0.98
bottlenose	UTSW	17	46,500,844 (GRCm38)	missense	possibly damaging	0.79
flipper	UTSW	17	46,525,892 (GRCm38)	missense	probably benign	0.05
orca	UTSW	17	46,525,135 (GRCm38)	missense	probably damaging	1.00
FR4340:Cul9	UTSW	17	46,500,853 (GRCm38)	small insertion	probably benign
FR4449:Cul9	UTSW	17	46,500,856 (GRCm38)	small insertion	probably benign
FR4737:Cul9	UTSW	17	46,500,858 (GRCm38)	small insertion	probably benign
FR4737:Cul9	UTSW	17	46,500,846 (GRCm38)	small insertion	probably benign
FR4976:Cul9	UTSW	17	46,500,853 (GRCm38)	small insertion	probably benign
FR4976:Cul9	UTSW	17	46,500,850 (GRCm38)	small insertion	probably benign
FR4976:Cul9	UTSW	17	46,500,848 (GRCm38)	small insertion	probably benign
FR4976:Cul9	UTSW	17	46,500,856 (GRCm38)	small insertion	probably benign
R0012:Cul9	UTSW	17	46,538,510 (GRCm38)	missense	probably benign	0.26
R0079:Cul9	UTSW	17	46,537,663 (GRCm38)	nonsense	probably null
R0143:Cul9	UTSW	17	46,526,410 (GRCm38)	missense	possibly damaging	0.65
R0390:Cul9	UTSW	17	46,528,589 (GRCm38)	missense	probably benign	0.34
R0401:Cul9	UTSW	17	46,541,704 (GRCm38)	missense	probably damaging	1.00
R0529:Cul9	UTSW	17	46,520,468 (GRCm38)	splice site	probably benign
R0815:Cul9	UTSW	17	46,537,822 (GRCm38)	splice site	probably null
R0863:Cul9	UTSW	17	46,537,822 (GRCm38)	splice site	probably null
R0972:Cul9	UTSW	17	46,522,175 (GRCm38)	missense	probably damaging	1.00
R1173:Cul9	UTSW	17	46,522,175 (GRCm38)	missense	probably damaging	1.00
R1216:Cul9	UTSW	17	46,522,175 (GRCm38)	missense	probably damaging	1.00
R1217:Cul9	UTSW	17	46,522,175 (GRCm38)	missense	probably damaging	1.00
R1261:Cul9	UTSW	17	46,525,782 (GRCm38)	missense	probably damaging	1.00
R1278:Cul9	UTSW	17	46,500,849 (GRCm38)	small deletion	probably benign
R1281:Cul9	UTSW	17	46,511,534 (GRCm38)	missense	probably damaging	1.00
R1349:Cul9	UTSW	17	46,522,175 (GRCm38)	missense	probably damaging	1.00
R1372:Cul9	UTSW	17	46,522,175 (GRCm38)	missense	probably damaging	1.00
R1403:Cul9	UTSW	17	46,522,175 (GRCm38)	missense	probably damaging	1.00
R1403:Cul9	UTSW	17	46,522,175 (GRCm38)	missense	probably damaging	1.00
R1405:Cul9	UTSW	17	46,522,175 (GRCm38)	missense	probably damaging	1.00
R1405:Cul9	UTSW	17	46,522,175 (GRCm38)	missense	probably damaging	1.00
R1467:Cul9	UTSW	17	46,525,373 (GRCm38)	missense	probably damaging	1.00
R1467:Cul9	UTSW	17	46,525,373 (GRCm38)	missense	probably damaging	1.00
R1482:Cul9	UTSW	17	46,508,547 (GRCm38)	missense	probably damaging	0.99
R1491:Cul9	UTSW	17	46,538,564 (GRCm38)	nonsense	probably null
R1618:Cul9	UTSW	17	46,525,892 (GRCm38)	missense	probably benign	0.05
R1641:Cul9	UTSW	17	46,543,560 (GRCm38)	missense	possibly damaging	0.96
R1679:Cul9	UTSW	17	46,521,156 (GRCm38)	missense	possibly damaging	0.90
R1771:Cul9	UTSW	17	46,537,812 (GRCm38)	missense	probably benign	0.41
R1803:Cul9	UTSW	17	46,503,097 (GRCm38)	missense	probably damaging	1.00
R2020:Cul9	UTSW	17	46,522,175 (GRCm38)	missense	probably damaging	1.00
R2046:Cul9	UTSW	17	46,543,733 (GRCm38)	missense	probably damaging	1.00
R2056:Cul9	UTSW	17	46,543,372 (GRCm38)	missense	probably benign
R2088:Cul9	UTSW	17	46,526,649 (GRCm38)	missense	probably damaging	1.00
R2415:Cul9	UTSW	17	46,543,438 (GRCm38)	missense	probably benign
R2925:Cul9	UTSW	17	46,510,981 (GRCm38)	missense	probably benign	0.08
R2964:Cul9	UTSW	17	46,502,228 (GRCm38)	missense	probably damaging	0.96
R2965:Cul9	UTSW	17	46,502,228 (GRCm38)	missense	probably damaging	0.96
R3690:Cul9	UTSW	17	46,504,031 (GRCm38)	splice site	probably null
R3847:Cul9	UTSW	17	46,525,135 (GRCm38)	missense	probably damaging	1.00
R4437:Cul9	UTSW	17	46,502,159 (GRCm38)	missense	probably damaging	1.00
R4470:Cul9	UTSW	17	46,538,336 (GRCm38)	missense	probably benign	0.00
R4540:Cul9	UTSW	17	46,503,089 (GRCm38)	missense	probably null	0.98
R4555:Cul9	UTSW	17	46,501,829 (GRCm38)	missense	possibly damaging	0.82
R4604:Cul9	UTSW	17	46,530,146 (GRCm38)	missense	probably damaging	0.99
R4646:Cul9	UTSW	17	46,539,017 (GRCm38)	nonsense	probably null
R4799:Cul9	UTSW	17	46,500,844 (GRCm38)	missense	possibly damaging	0.79
R4822:Cul9	UTSW	17	46,530,051 (GRCm38)	missense	probably benign	0.01
R4964:Cul9	UTSW	17	46,538,525 (GRCm38)	missense	probably damaging	1.00
R4965:Cul9	UTSW	17	46,538,525 (GRCm38)	missense	probably damaging	1.00
R5027:Cul9	UTSW	17	46,500,782 (GRCm38)	missense	probably damaging	0.99
R5185:Cul9	UTSW	17	46,525,832 (GRCm38)	missense	possibly damaging	0.95
R5237:Cul9	UTSW	17	46,543,467 (GRCm38)	missense	probably benign	0.00
R5278:Cul9	UTSW	17	46,510,873 (GRCm38)	missense	probably damaging	1.00
R5361:Cul9	UTSW	17	46,500,849 (GRCm38)	small deletion	probably benign
R5455:Cul9	UTSW	17	46,510,846 (GRCm38)	splice site	probably null
R5592:Cul9	UTSW	17	46,520,591 (GRCm38)	missense	probably benign	0.00
R5597:Cul9	UTSW	17	46,502,665 (GRCm38)	missense	possibly damaging	0.56
R5613:Cul9	UTSW	17	46,503,844 (GRCm38)	missense	probably damaging	1.00
R6122:Cul9	UTSW	17	46,521,928 (GRCm38)	missense	possibly damaging	0.72
R6135:Cul9	UTSW	17	46,521,453 (GRCm38)	missense	probably benign
R6352:Cul9	UTSW	17	46,511,315 (GRCm38)	missense	probably benign	0.00
R6376:Cul9	UTSW	17	46,508,563 (GRCm38)	missense	probably damaging	1.00
R6868:Cul9	UTSW	17	46,522,183 (GRCm38)	missense	possibly damaging	0.73
R6898:Cul9	UTSW	17	46,511,026 (GRCm38)	missense	possibly damaging	0.87
R7090:Cul9	UTSW	17	46,500,839 (GRCm38)	missense	probably damaging	0.96
R7193:Cul9	UTSW	17	46,538,497 (GRCm38)	missense	probably damaging	0.98
R7221:Cul9	UTSW	17	46,528,565 (GRCm38)	missense	probably damaging	0.99
R7320:Cul9	UTSW	17	46,510,909 (GRCm38)	missense	possibly damaging	0.80
R7348:Cul9	UTSW	17	46,510,993 (GRCm38)	missense	possibly damaging	0.89
R7463:Cul9	UTSW	17	46,520,476 (GRCm38)	splice site	probably null
R7480:Cul9	UTSW	17	46,537,812 (GRCm38)	missense	probably benign	0.41
R7573:Cul9	UTSW	17	46,519,910 (GRCm38)	missense	probably benign
R7582:Cul9	UTSW	17	46,510,979 (GRCm38)	missense	probably damaging	1.00
R7605:Cul9	UTSW	17	46,541,732 (GRCm38)	missense	probably damaging	0.99
R7684:Cul9	UTSW	17	46,509,889 (GRCm38)	missense	probably damaging	1.00
R7830:Cul9	UTSW	17	46,540,311 (GRCm38)	missense	probably benign	0.37
R7834:Cul9	UTSW	17	46,525,704 (GRCm38)	splice site	probably null
R8131:Cul9	UTSW	17	46,511,242 (GRCm38)	missense	probably damaging	1.00
R8192:Cul9	UTSW	17	46,538,347 (GRCm38)	missense	probably benign	0.01
R8231:Cul9	UTSW	17	46,520,501 (GRCm38)	missense	probably damaging	0.99
R8248:Cul9	UTSW	17	46,530,014 (GRCm38)	missense	probably damaging	0.99
R8504:Cul9	UTSW	17	46,503,580 (GRCm38)	missense	probably damaging	1.00
R8550:Cul9	UTSW	17	46,519,846 (GRCm38)	missense	probably damaging	1.00
R8716:Cul9	UTSW	17	46,527,914 (GRCm38)	missense	probably benign	0.28
R8769:Cul9	UTSW	17	46,521,902 (GRCm38)	missense	possibly damaging	0.85
R8893:Cul9	UTSW	17	46,500,849 (GRCm38)	small deletion	probably benign
R8904:Cul9	UTSW	17	46,520,501 (GRCm38)	missense	probably damaging	0.99
R8936:Cul9	UTSW	17	46,528,602 (GRCm38)	missense	possibly damaging	0.82
R8972:Cul9	UTSW	17	46,543,251 (GRCm38)	missense	probably damaging	1.00
R9003:Cul9	UTSW	17	46,525,075 (GRCm38)	missense	possibly damaging	0.78
R9012:Cul9	UTSW	17	46,543,521 (GRCm38)	missense	probably benign
R9056:Cul9	UTSW	17	46,543,770 (GRCm38)	missense	probably damaging	0.99
R9071:Cul9	UTSW	17	46,526,453 (GRCm38)	missense	probably benign
R9162:Cul9	UTSW	17	46,526,603 (GRCm38)	missense	probably benign	0.32
R9476:Cul9	UTSW	17	46,510,907 (GRCm38)	missense	probably damaging	1.00
R9526:Cul9	UTSW	17	46,530,100 (GRCm38)	missense	probably benign	0.41
R9563:Cul9	UTSW	17	46,509,971 (GRCm38)	missense	probably benign	0.01
R9568:Cul9	UTSW	17	46,520,118 (GRCm38)	missense	possibly damaging	0.56
R9610:Cul9	UTSW	17	46,519,897 (GRCm38)	missense	possibly damaging	0.96
R9611:Cul9	UTSW	17	46,519,897 (GRCm38)	missense	possibly damaging	0.96
R9705:Cul9	UTSW	17	46,543,300 (GRCm38)	missense	probably damaging	1.00
R9765:Cul9	UTSW	17	46,539,298 (GRCm38)	missense	probably benign	0.18
RF011:Cul9	UTSW	17	46,500,848 (GRCm38)	small insertion	probably benign
RF016:Cul9	UTSW	17	46,500,863 (GRCm38)	nonsense	probably null
RF026:Cul9	UTSW	17	46,500,869 (GRCm38)	nonsense	probably null
RF027:Cul9	UTSW	17	46,500,848 (GRCm38)	small insertion	probably benign
RF030:Cul9	UTSW	17	46,500,869 (GRCm38)	small insertion	probably benign
RF033:Cul9	UTSW	17	46,500,854 (GRCm38)	small insertion	probably benign
RF039:Cul9	UTSW	17	46,500,854 (GRCm38)	small insertion	probably benign
RF041:Cul9	UTSW	17	46,500,854 (GRCm38)	nonsense	probably null
RF042:Cul9	UTSW	17	46,540,615 (GRCm38)	frame shift	probably null
RF057:Cul9	UTSW	17	46,500,863 (GRCm38)	nonsense	probably null
Z1176:Cul9	UTSW	17	46,520,585 (GRCm38)	nonsense	probably null
Z1176:Cul9	UTSW	17	46,520,576 (GRCm38)	nonsense	probably null
Z1177:Cul9	UTSW	17	46,537,797 (GRCm38)	missense	probably benign	0.14

Predicted Primers

PCR Primer
(F):5'- TGTTGCTCTGCTGGAACTCG -3'
(R):5'- ATAACAGCCCAGAGTCAGGAGC -3'

Sequencing Primer
(F):5'- TGCTGGAACTCGCCCTC -3'
(R):5'- TCCCCGTGTCTCACAAAGGAG -3'

Posted On

2019-06-26