Incidental Mutation 'R7310:Dnah7c'
| ID |
567469 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dnah7c
|
| Ensembl Gene |
ENSMUSG00000101337 |
| Gene Name |
dynein, axonemal, heavy chain 7C |
| Synonyms |
Dnahc7c |
| MMRRC Submission |
045409-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.340)
|
| Stock # |
R7310 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
46464752-46846636 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 46636127 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Valine
at position 1117
(M1117V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000140430
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000189749]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000189749
AA Change: M1117V
PolyPhen 2
Score 0.939 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000140430
Gene: ENSMUSG00000101337
AA Change: M1117V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
15 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
714 |
746 |
N/A |
INTRINSIC |
|
Pfam:DHC_N2
|
754 |
1167 |
2.2e-138 |
PFAM |
|
AAA
|
1320 |
1459 |
4e-3 |
SMART |
|
Blast:AAA
|
1601 |
1829 |
4e-87 |
BLAST |
|
AAA
|
1968 |
2116 |
8.7e-4 |
SMART |
|
Pfam:AAA_8
|
2303 |
2574 |
6.2e-73 |
PFAM |
|
Pfam:MT
|
2586 |
2935 |
5.4e-52 |
PFAM |
|
Pfam:AAA_9
|
2953 |
3183 |
7.4e-63 |
PFAM |
|
Pfam:Dynein_heavy
|
3312 |
4021 |
1.3e-250 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810021J22Rik |
A |
T |
11: 58,771,094 (GRCm39) |
Q192L |
possibly damaging |
Het |
| Abat |
G |
A |
16: 8,423,457 (GRCm39) |
R250Q |
probably null |
Het |
| Abcg3 |
A |
C |
5: 105,114,632 (GRCm39) |
F295C |
probably benign |
Het |
| Abl1 |
T |
C |
2: 31,690,604 (GRCm39) |
S708P |
possibly damaging |
Het |
| Acap2 |
A |
T |
16: 30,926,972 (GRCm39) |
Y489* |
probably null |
Het |
| Akr1c6 |
A |
T |
13: 4,486,354 (GRCm39) |
M54L |
probably benign |
Het |
| Arhgap5 |
A |
T |
12: 52,589,270 (GRCm39) |
|
probably null |
Het |
| Asap1 |
A |
G |
15: 63,971,379 (GRCm39) |
|
probably null |
Het |
| Atrnl1 |
A |
T |
19: 57,630,856 (GRCm39) |
N208Y |
possibly damaging |
Het |
| BC028528 |
CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT |
CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT |
3: 95,795,448 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
GTTCTGTGGTCACTG |
GTTCTGTGGTCACTGATTCTGTGGTCACTG |
3: 95,795,485 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
G |
GGGGTCACTGGTTCTT |
3: 95,795,460 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
ACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTC |
ACTGGTTCTGTGGTCCCTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTC |
3: 95,795,451 (GRCm39) |
|
probably benign |
Het |
| Bmi1 |
T |
C |
2: 18,689,230 (GRCm39) |
S305P |
probably benign |
Het |
| Bpifc |
T |
A |
10: 85,798,891 (GRCm39) |
I431F |
probably damaging |
Het |
| C130050O18Rik |
A |
T |
5: 139,400,993 (GRCm39) |
M349L |
probably benign |
Het |
| Cacna2d1 |
A |
T |
5: 16,519,914 (GRCm39) |
D428V |
probably damaging |
Het |
| Card14 |
A |
C |
11: 119,217,005 (GRCm39) |
Q363P |
probably null |
Het |
| Cdca2 |
A |
T |
14: 67,950,673 (GRCm39) |
L86H |
probably damaging |
Het |
| Cdh22 |
G |
T |
2: 164,954,214 (GRCm39) |
S769* |
probably null |
Het |
| Cdhr17 |
A |
G |
5: 17,075,246 (GRCm39) |
Y872C |
possibly damaging |
Het |
| Cep164 |
T |
C |
9: 45,686,664 (GRCm39) |
E690G |
probably damaging |
Het |
| Cluh |
A |
G |
11: 74,560,285 (GRCm39) |
H1304R |
probably benign |
Het |
| Daxx |
C |
A |
17: 34,129,435 (GRCm39) |
D5E |
possibly damaging |
Het |
| Entpd3 |
T |
A |
9: 120,389,821 (GRCm39) |
|
probably null |
Het |
| Esr1 |
G |
A |
10: 4,889,259 (GRCm39) |
A386T |
probably damaging |
Het |
| Etv5 |
G |
A |
16: 22,220,487 (GRCm39) |
P300L |
probably benign |
Het |
| Exoc3l |
A |
T |
8: 106,020,340 (GRCm39) |
L195Q |
probably damaging |
Het |
| Exog |
T |
C |
9: 119,274,069 (GRCm39) |
L18P |
unknown |
Het |
| Fgfr1 |
T |
A |
8: 26,052,331 (GRCm39) |
V219D |
probably benign |
Het |
| Gna14 |
A |
T |
19: 16,511,113 (GRCm39) |
Q54L |
|
Het |
| Gnb5 |
T |
C |
9: 75,221,570 (GRCm39) |
L48P |
probably benign |
Het |
| Gpbp1 |
A |
G |
13: 111,589,924 (GRCm39) |
I57T |
probably benign |
Het |
| Hnrnpa1 |
T |
A |
15: 103,149,884 (GRCm39) |
D48E |
probably damaging |
Het |
| Hrc |
T |
A |
7: 44,985,227 (GRCm39) |
L126* |
probably null |
Het |
| Hspa8 |
T |
G |
9: 40,714,704 (GRCm39) |
D333E |
probably benign |
Het |
| Igsf3 |
T |
A |
3: 101,338,895 (GRCm39) |
V403D |
probably benign |
Het |
| Itga10 |
C |
A |
3: 96,555,475 (GRCm39) |
A143D |
probably damaging |
Het |
| Kdr |
T |
A |
5: 76,104,985 (GRCm39) |
I1082F |
probably damaging |
Het |
| Klk1b11 |
A |
T |
7: 43,428,254 (GRCm39) |
I242F |
probably damaging |
Het |
| Kng2 |
G |
A |
16: 22,806,522 (GRCm39) |
T559I |
probably benign |
Het |
| Map1b |
G |
A |
13: 99,570,163 (GRCm39) |
P853S |
unknown |
Het |
| Mmp13 |
T |
C |
9: 7,280,880 (GRCm39) |
I421T |
possibly damaging |
Het |
| Mpeg1 |
A |
T |
19: 12,439,615 (GRCm39) |
T358S |
probably damaging |
Het |
| Msantd5l |
A |
C |
11: 51,145,474 (GRCm39) |
W38G |
probably damaging |
Het |
| Mttp |
T |
C |
3: 137,800,783 (GRCm39) |
D759G |
probably damaging |
Het |
| Mup17 |
T |
A |
4: 61,511,929 (GRCm39) |
Y115F |
possibly damaging |
Het |
| Myo1a |
G |
T |
10: 127,541,697 (GRCm39) |
A79S |
probably damaging |
Het |
| Myo9a |
T |
A |
9: 59,778,436 (GRCm39) |
N1397K |
probably benign |
Het |
| Nadk2 |
T |
C |
15: 9,103,469 (GRCm39) |
|
probably null |
Het |
| Ncf1 |
A |
T |
5: 134,250,615 (GRCm39) |
S402T |
probably benign |
Het |
| Ndufb10 |
T |
C |
17: 24,941,188 (GRCm39) |
D145G |
probably damaging |
Het |
| Nlgn2 |
G |
A |
11: 69,721,409 (GRCm39) |
T163M |
possibly damaging |
Het |
| Nol4 |
A |
T |
18: 22,903,801 (GRCm39) |
H172Q |
|
Het |
| Nup205 |
T |
A |
6: 35,202,904 (GRCm39) |
D1370E |
possibly damaging |
Het |
| Or1e32 |
A |
C |
11: 73,705,112 (GRCm39) |
N265K |
probably damaging |
Het |
| Or51ab3 |
T |
A |
7: 103,201,892 (GRCm39) |
I300N |
probably damaging |
Het |
| Or5b97 |
A |
G |
19: 12,878,637 (GRCm39) |
F169S |
probably damaging |
Het |
| Pkd1l2 |
A |
G |
8: 117,750,773 (GRCm39) |
V1746A |
probably benign |
Het |
| Plin2 |
T |
A |
4: 86,586,628 (GRCm39) |
I68F |
probably benign |
Het |
| Proc |
A |
T |
18: 32,268,952 (GRCm39) |
M11K |
probably benign |
Het |
| Rif1 |
T |
C |
2: 51,995,631 (GRCm39) |
V950A |
probably benign |
Het |
| Rmc1 |
A |
G |
18: 12,317,972 (GRCm39) |
K362E |
probably benign |
Het |
| Rnf208 |
C |
A |
2: 25,133,587 (GRCm39) |
P94T |
probably damaging |
Het |
| Rundc3b |
A |
T |
5: 8,571,011 (GRCm39) |
Y269* |
probably null |
Het |
| Senp7 |
T |
C |
16: 56,006,445 (GRCm39) |
V950A |
probably benign |
Het |
| Sipa1l1 |
T |
C |
12: 82,419,269 (GRCm39) |
V649A |
probably damaging |
Het |
| Sipa1l3 |
G |
T |
7: 29,099,121 (GRCm39) |
H383N |
probably benign |
Het |
| Slc12a5 |
G |
A |
2: 164,834,360 (GRCm39) |
V794M |
probably damaging |
Het |
| Slc7a7 |
A |
G |
14: 54,616,482 (GRCm39) |
I200T |
probably damaging |
Het |
| Spdye4b |
A |
C |
5: 143,188,103 (GRCm39) |
I199L |
probably damaging |
Het |
| Styxl2 |
G |
A |
1: 165,926,300 (GRCm39) |
T1104I |
possibly damaging |
Het |
| Tle4 |
A |
T |
19: 14,495,155 (GRCm39) |
H191Q |
probably benign |
Het |
| Tnfsf13b |
C |
A |
8: 10,081,651 (GRCm39) |
S271* |
probably null |
Het |
| Tnks2 |
G |
A |
19: 36,856,839 (GRCm39) |
V855I |
probably benign |
Het |
| Trank1 |
T |
C |
9: 111,196,194 (GRCm39) |
L1406S |
probably damaging |
Het |
| Trhde |
T |
C |
10: 114,636,478 (GRCm39) |
E243G |
probably damaging |
Het |
| Trim25 |
A |
T |
11: 88,906,608 (GRCm39) |
N448I |
probably benign |
Het |
| Trim31 |
T |
A |
17: 37,218,194 (GRCm39) |
M308K |
probably benign |
Het |
| Ugt2b36 |
A |
T |
5: 87,214,138 (GRCm39) |
V502E |
possibly damaging |
Het |
| Usp10 |
A |
C |
8: 120,668,344 (GRCm39) |
D215A |
possibly damaging |
Het |
| Usp33 |
T |
G |
3: 152,066,026 (GRCm39) |
L102* |
probably null |
Het |
| Wdr12 |
A |
T |
1: 60,121,734 (GRCm39) |
C272* |
probably null |
Het |
| Xndc1 |
A |
C |
7: 101,727,938 (GRCm39) |
|
probably null |
Het |
| Zkscan2 |
T |
C |
7: 123,089,276 (GRCm39) |
I332V |
possibly damaging |
Het |
| Zswim5 |
A |
T |
4: 116,841,885 (GRCm39) |
T822S |
probably benign |
Het |
|
| Other mutations in Dnah7c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00559:Dnah7c
|
APN |
1 |
46,846,449 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL02958:Dnah7c
|
APN |
1 |
46,696,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03035:Dnah7c
|
APN |
1 |
46,563,277 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL03161:Dnah7c
|
APN |
1 |
46,506,456 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL03178:Dnah7c
|
APN |
1 |
46,506,525 (GRCm39) |
missense |
probably benign |
|
|
IGL03052:Dnah7c
|
UTSW |
1 |
46,671,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0751:Dnah7c
|
UTSW |
1 |
46,505,065 (GRCm39) |
missense |
probably benign |
|
|
R1029:Dnah7c
|
UTSW |
1 |
46,651,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3104:Dnah7c
|
UTSW |
1 |
46,837,439 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3977:Dnah7c
|
UTSW |
1 |
46,668,071 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4003:Dnah7c
|
UTSW |
1 |
46,720,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4133:Dnah7c
|
UTSW |
1 |
46,705,150 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4303:Dnah7c
|
UTSW |
1 |
46,787,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4329:Dnah7c
|
UTSW |
1 |
46,688,441 (GRCm39) |
missense |
probably benign |
0.33 |
|
R4434:Dnah7c
|
UTSW |
1 |
46,705,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4457:Dnah7c
|
UTSW |
1 |
46,779,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4470:Dnah7c
|
UTSW |
1 |
46,787,795 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4507:Dnah7c
|
UTSW |
1 |
46,805,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4527:Dnah7c
|
UTSW |
1 |
46,572,091 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4571:Dnah7c
|
UTSW |
1 |
46,572,376 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4589:Dnah7c
|
UTSW |
1 |
46,553,743 (GRCm39) |
nonsense |
probably null |
|
|
R4731:Dnah7c
|
UTSW |
1 |
46,809,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4732:Dnah7c
|
UTSW |
1 |
46,809,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4733:Dnah7c
|
UTSW |
1 |
46,809,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4747:Dnah7c
|
UTSW |
1 |
46,572,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4845:Dnah7c
|
UTSW |
1 |
46,832,692 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4873:Dnah7c
|
UTSW |
1 |
46,728,085 (GRCm39) |
missense |
probably benign |
|
|
R4875:Dnah7c
|
UTSW |
1 |
46,728,085 (GRCm39) |
missense |
probably benign |
|
|
R4916:Dnah7c
|
UTSW |
1 |
46,634,168 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5241:Dnah7c
|
UTSW |
1 |
46,569,660 (GRCm39) |
missense |
probably benign |
|
|
R5279:Dnah7c
|
UTSW |
1 |
46,558,429 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5327:Dnah7c
|
UTSW |
1 |
46,704,728 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5546:Dnah7c
|
UTSW |
1 |
46,705,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5605:Dnah7c
|
UTSW |
1 |
46,837,395 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R5637:Dnah7c
|
UTSW |
1 |
46,799,521 (GRCm39) |
splice site |
probably null |
|
|
R5639:Dnah7c
|
UTSW |
1 |
46,778,828 (GRCm39) |
missense |
probably benign |
|
|
R5663:Dnah7c
|
UTSW |
1 |
46,574,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5718:Dnah7c
|
UTSW |
1 |
46,787,826 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R5759:Dnah7c
|
UTSW |
1 |
46,654,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5771:Dnah7c
|
UTSW |
1 |
46,678,825 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5784:Dnah7c
|
UTSW |
1 |
46,563,228 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5800:Dnah7c
|
UTSW |
1 |
46,686,175 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5933:Dnah7c
|
UTSW |
1 |
46,558,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5948:Dnah7c
|
UTSW |
1 |
46,711,657 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6034:Dnah7c
|
UTSW |
1 |
46,496,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6034:Dnah7c
|
UTSW |
1 |
46,496,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6487:Dnah7c
|
UTSW |
1 |
46,808,284 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6536:Dnah7c
|
UTSW |
1 |
46,697,450 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6614:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6614:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dnah7c
|
UTSW |
1 |
46,554,599 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6615:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6649:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6649:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6650:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6650:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6651:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6651:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6653:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6653:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6714:Dnah7c
|
UTSW |
1 |
46,779,966 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6729:Dnah7c
|
UTSW |
1 |
46,711,681 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6760:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6760:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6763:Dnah7c
|
UTSW |
1 |
46,668,050 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6866:Dnah7c
|
UTSW |
1 |
46,696,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6880:Dnah7c
|
UTSW |
1 |
46,566,831 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6988:Dnah7c
|
UTSW |
1 |
46,705,373 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6995:Dnah7c
|
UTSW |
1 |
46,494,973 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7007:Dnah7c
|
UTSW |
1 |
46,571,910 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7086:Dnah7c
|
UTSW |
1 |
46,789,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7128:Dnah7c
|
UTSW |
1 |
46,566,645 (GRCm39) |
missense |
probably benign |
|
|
R7131:Dnah7c
|
UTSW |
1 |
46,720,932 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7135:Dnah7c
|
UTSW |
1 |
46,572,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7171:Dnah7c
|
UTSW |
1 |
46,719,898 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7176:Dnah7c
|
UTSW |
1 |
46,469,969 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7221:Dnah7c
|
UTSW |
1 |
46,494,937 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7319:Dnah7c
|
UTSW |
1 |
46,819,935 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7319:Dnah7c
|
UTSW |
1 |
46,823,608 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7404:Dnah7c
|
UTSW |
1 |
46,705,223 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7452:Dnah7c
|
UTSW |
1 |
46,686,196 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7515:Dnah7c
|
UTSW |
1 |
46,496,450 (GRCm39) |
missense |
probably benign |
|
|
R7534:Dnah7c
|
UTSW |
1 |
46,809,227 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7542:Dnah7c
|
UTSW |
1 |
46,823,658 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7605:Dnah7c
|
UTSW |
1 |
46,671,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7643:Dnah7c
|
UTSW |
1 |
46,641,973 (GRCm39) |
missense |
probably benign |
|
|
R7770:Dnah7c
|
UTSW |
1 |
46,665,460 (GRCm39) |
splice site |
probably null |
|
|
R7884:Dnah7c
|
UTSW |
1 |
46,830,929 (GRCm39) |
missense |
probably benign |
0.23 |
|
R7899:Dnah7c
|
UTSW |
1 |
46,553,861 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8025:Dnah7c
|
UTSW |
1 |
46,496,456 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8057:Dnah7c
|
UTSW |
1 |
46,728,112 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8191:Dnah7c
|
UTSW |
1 |
46,646,618 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R8255:Dnah7c
|
UTSW |
1 |
46,698,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8428:Dnah7c
|
UTSW |
1 |
46,711,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8441:Dnah7c
|
UTSW |
1 |
46,572,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8485:Dnah7c
|
UTSW |
1 |
46,719,952 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8559:Dnah7c
|
UTSW |
1 |
46,764,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8752:Dnah7c
|
UTSW |
1 |
46,711,701 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8869:Dnah7c
|
UTSW |
1 |
46,671,504 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9058:Dnah7c
|
UTSW |
1 |
46,805,816 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9121:Dnah7c
|
UTSW |
1 |
46,816,896 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9121:Dnah7c
|
UTSW |
1 |
46,704,650 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9246:Dnah7c
|
UTSW |
1 |
46,571,934 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R9319:Dnah7c
|
UTSW |
1 |
46,521,168 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9388:Dnah7c
|
UTSW |
1 |
46,779,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,654,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,506,462 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,799,476 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,686,152 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1176:Dnah7c
|
UTSW |
1 |
46,678,825 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Dnah7c
|
UTSW |
1 |
46,693,263 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTGCTTTGTACCCATTTAAATGT -3'
(R):5'- CCATTTCAGATTAAATCACTCATTTCC -3'
Sequencing Primer
(F):5'- CCTGACATGTGAGGAACT -3'
(R):5'- GGCTCCCATGTATTGACAGACTG -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation