Mutagenetix > Incidental Mutation

Incidental Mutation 'R7310:Trank1'

567515

Institutional Source

Beutler Lab

Gene Symbol

Trank1

Ensembl Gene

ENSMUSG00000062296

Gene Name

tetratricopeptide repeat and ankyrin repeat containing 1

Synonyms

A230061D21Rik, LOC235639, C030048J01Rik, Lba1

MMRRC Submission

045409-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7310 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

111311739-111395775 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 111367126 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Serine at position 1406 (L1406S)

Ref Sequence

ENSEMBL: ENSMUSP00000077697 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000078626]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000078626
AA Change: L1406S

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000077697
Gene: ENSMUSG00000062296
AA Change: L1406S

Domain	Start	End	E-Value	Type
low complexity region	4	30	N/A	INTRINSIC
low complexity region	34	52	N/A	INTRINSIC
low complexity region	113	129	N/A	INTRINSIC
Blast:TPR	144	177	1e-15	BLAST
Blast:TPR	178	209	8e-13	BLAST
Blast:ANK	332	361	1e-6	BLAST
ANK	369	405	5.29e0	SMART
ANK	538	567	2.11e2	SMART
ANK	572	609	7.29e2	SMART
ANK	621	652	1.21e2	SMART
low complexity region	887	895	N/A	INTRINSIC
low complexity region	1152	1172	N/A	INTRINSIC
Blast:AAA	1351	1569	1e-6	BLAST
low complexity region	2166	2177	N/A	INTRINSIC
low complexity region	2395	2411	N/A	INTRINSIC
low complexity region	2636	2649	N/A	INTRINSIC
low complexity region	2966	2983	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.8%

Validation Efficiency

Allele List at MGI

All alleles(2) : Targeted, other(2)

Other mutations in this stock

Total: 86 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2810021J22Rik	A	T	11: 58,880,268 (GRCm38)	Q192L	possibly damaging	Het
3110002H16Rik	A	G	18: 12,184,915 (GRCm38)	K362E	probably benign	Het
Abat	G	A	16: 8,605,593 (GRCm38)	R250Q	probably null	Het
Abcg3	A	C	5: 104,966,766 (GRCm38)	F295C	probably benign	Het
Abl1	T	C	2: 31,800,592 (GRCm38)	S708P	possibly damaging	Het
Acap2	A	T	16: 31,108,154 (GRCm38)	Y489*	probably null	Het
Akr1c6	A	T	13: 4,436,355 (GRCm38)	M54L	probably benign	Het
Arhgap5	A	T	12: 52,542,487 (GRCm38)		probably null	Het
Asap1	A	G	15: 64,099,530 (GRCm38)		probably null	Het
Atrnl1	A	T	19: 57,642,424 (GRCm38)	N208Y	possibly damaging	Het
BC028528	CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT	CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT	3: 95,888,136 (GRCm38)		probably benign	Het
BC028528	ACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTC	ACTGGTTCTGTGGTCCCTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTC	3: 95,888,139 (GRCm38)		probably benign	Het
BC028528	G	GGGGTCACTGGTTCTT	3: 95,888,148 (GRCm38)		probably benign	Het
BC028528	GTTCTGTGGTCACTG	GTTCTGTGGTCACTGATTCTGTGGTCACTG	3: 95,888,173 (GRCm38)		probably benign	Het
BC049762	A	C	11: 51,254,647 (GRCm38)	W38G	probably damaging	Het
Bmi1	T	C	2: 18,684,419 (GRCm38)	S305P	probably benign	Het
Bpifc	T	A	10: 85,963,027 (GRCm38)	I431F	probably damaging	Het
C130050O18Rik	A	T	5: 139,415,238 (GRCm38)	M349L	probably benign	Het
Cacna2d1	A	T	5: 16,314,916 (GRCm38)	D428V	probably damaging	Het
Card14	A	C	11: 119,326,179 (GRCm38)	Q363P	probably null	Het
Cdca2	A	T	14: 67,713,224 (GRCm38)	L86H	probably damaging	Het
Cdh22	G	T	2: 165,112,294 (GRCm38)	S769*	probably null	Het
Cep164	T	C	9: 45,775,366 (GRCm38)	E690G	probably damaging	Het
Cluh	A	G	11: 74,669,459 (GRCm38)	H1304R	probably benign	Het
Daxx	C	A	17: 33,910,461 (GRCm38)	D5E	possibly damaging	Het
Dnah7c	A	G	1: 46,596,967 (GRCm38)	M1117V	possibly damaging	Het
Dusp27	G	A	1: 166,098,731 (GRCm38)	T1104I	possibly damaging	Het
Entpd3	T	A	9: 120,560,755 (GRCm38)		probably null	Het
Esr1	G	A	10: 4,939,259 (GRCm38)	A386T	probably damaging	Het
Etv5	G	A	16: 22,401,737 (GRCm38)	P300L	probably benign	Het
Exoc3l	A	T	8: 105,293,708 (GRCm38)	L195Q	probably damaging	Het
Exog	T	C	9: 119,445,003 (GRCm38)	L18P	unknown	Het
Fgfr1	T	A	8: 25,562,315 (GRCm38)	V219D	probably benign	Het
Gm28710	A	G	5: 16,870,248 (GRCm38)	Y872C	possibly damaging	Het
Gna14	A	T	19: 16,533,749 (GRCm38)	Q54L		Het
Gnb5	T	C	9: 75,314,288 (GRCm38)	L48P	probably benign	Het
Gpbp1	A	G	13: 111,453,390 (GRCm38)	I57T	probably benign	Het
Hnrnpa1	T	A	15: 103,241,457 (GRCm38)	D48E	probably damaging	Het
Hrc	T	A	7: 45,335,803 (GRCm38)	L126*	probably null	Het
Hspa8	T	G	9: 40,803,408 (GRCm38)	D333E	probably benign	Het
Igsf3	T	A	3: 101,431,579 (GRCm38)	V403D	probably benign	Het
Itga10	C	A	3: 96,648,159 (GRCm38)	A143D	probably damaging	Het
Kdr	T	A	5: 75,944,325 (GRCm38)	I1082F	probably damaging	Het
Klk11	A	T	7: 43,778,830 (GRCm38)	I242F	probably damaging	Het
Kng2	G	A	16: 22,987,772 (GRCm38)	T559I	probably benign	Het
Map1b	G	A	13: 99,433,655 (GRCm38)	P853S	unknown	Het
Mmp13	T	C	9: 7,280,880 (GRCm38)	I421T	possibly damaging	Het
Mpeg1	A	T	19: 12,462,251 (GRCm38)	T358S	probably damaging	Het
Mttp	T	C	3: 138,095,022 (GRCm38)	D759G	probably damaging	Het
Mup17	T	A	4: 61,593,692 (GRCm38)	Y115F	possibly damaging	Het
Myo1a	G	T	10: 127,705,828 (GRCm38)	A79S	probably damaging	Het
Myo9a	T	A	9: 59,871,153 (GRCm38)	N1397K	probably benign	Het
Nadk2	T	C	15: 9,103,381 (GRCm38)		probably null	Het
Ncf1	A	T	5: 134,221,761 (GRCm38)	S402T	probably benign	Het
Ndufb10	T	C	17: 24,722,214 (GRCm38)	D145G	probably damaging	Het
Nlgn2	G	A	11: 69,830,583 (GRCm38)	T163M	possibly damaging	Het
Nol4	A	T	18: 22,770,744 (GRCm38)	H172Q		Het
Nup205	T	A	6: 35,225,969 (GRCm38)	D1370E	possibly damaging	Het
Olfr1447	A	G	19: 12,901,273 (GRCm38)	F169S	probably damaging	Het
Olfr392	A	C	11: 73,814,286 (GRCm38)	N265K	probably damaging	Het
Olfr613	T	A	7: 103,552,685 (GRCm38)	I300N	probably damaging	Het
Pkd1l2	A	G	8: 117,024,034 (GRCm38)	V1746A	probably benign	Het
Plin2	T	A	4: 86,668,391 (GRCm38)	I68F	probably benign	Het
Proc	A	T	18: 32,135,899 (GRCm38)	M11K	probably benign	Het
Rif1	T	C	2: 52,105,619 (GRCm38)	V950A	probably benign	Het
Rnf208	C	A	2: 25,243,575 (GRCm38)	P94T	probably damaging	Het
Rundc3b	A	T	5: 8,521,011 (GRCm38)	Y269*	probably null	Het
Senp7	T	C	16: 56,186,082 (GRCm38)	V950A	probably benign	Het
Sipa1l1	T	C	12: 82,372,495 (GRCm38)	V649A	probably damaging	Het
Sipa1l3	G	T	7: 29,399,696 (GRCm38)	H383N	probably benign	Het
Slc12a5	G	A	2: 164,992,440 (GRCm38)	V794M	probably damaging	Het
Slc7a7	A	G	14: 54,379,025 (GRCm38)	I200T	probably damaging	Het
Spdye4b	A	C	5: 143,202,348 (GRCm38)	I199L	probably damaging	Het
Tle4	A	T	19: 14,517,791 (GRCm38)	H191Q	probably benign	Het
Tnfsf13b	C	A	8: 10,031,651 (GRCm38)	S271*	probably null	Het
Tnks2	G	A	19: 36,879,439 (GRCm38)	V855I	probably benign	Het
Trhde	T	C	10: 114,800,573 (GRCm38)	E243G	probably damaging	Het
Trim25	A	T	11: 89,015,782 (GRCm38)	N448I	probably benign	Het
Trim31	T	A	17: 36,907,302 (GRCm38)	M308K	probably benign	Het
Ugt2b36	A	T	5: 87,066,279 (GRCm38)	V502E	possibly damaging	Het
Usp10	A	C	8: 119,941,605 (GRCm38)	D215A	possibly damaging	Het
Usp33	T	G	3: 152,360,389 (GRCm38)	L102*	probably null	Het
Wdr12	A	T	1: 60,082,575 (GRCm38)	C272*	probably null	Het
Xndc1	A	C	7: 102,078,731 (GRCm38)		probably null	Het
Zkscan2	T	C	7: 123,490,053 (GRCm38)	I332V	possibly damaging	Het
Zswim5	A	T	4: 116,984,688 (GRCm38)	T822S	probably benign	Het

Other mutations in Trank1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00234:Trank1	APN	9	111,392,609 (GRCm38)	missense	probably damaging	1.00
IGL00467:Trank1	APN	9	111,364,666 (GRCm38)	splice site	probably benign
IGL00569:Trank1	APN	9	111,345,511 (GRCm38)	missense	possibly damaging	0.69
IGL00585:Trank1	APN	9	111,349,290 (GRCm38)	missense	possibly damaging	0.82
IGL01070:Trank1	APN	9	111,366,793 (GRCm38)	missense	probably damaging	1.00
IGL01134:Trank1	APN	9	111,391,781 (GRCm38)	missense	probably benign
IGL01154:Trank1	APN	9	111,386,400 (GRCm38)	missense	probably benign	0.00
IGL01355:Trank1	APN	9	111,365,520 (GRCm38)	missense	possibly damaging	0.94
IGL01407:Trank1	APN	9	111,364,722 (GRCm38)	missense	probably damaging	0.99
IGL01410:Trank1	APN	9	111,365,049 (GRCm38)	missense	probably benign	0.00
IGL01410:Trank1	APN	9	111,365,259 (GRCm38)	missense	probably benign	0.00
IGL01504:Trank1	APN	9	111,373,544 (GRCm38)	missense	probably damaging	1.00
IGL01744:Trank1	APN	9	111,349,363 (GRCm38)	missense	probably damaging	1.00
IGL02043:Trank1	APN	9	111,363,960 (GRCm38)	missense	probably damaging	0.98
IGL02104:Trank1	APN	9	111,390,712 (GRCm38)	missense	possibly damaging	0.85
IGL02193:Trank1	APN	9	111,367,276 (GRCm38)	missense	probably benign	0.43
IGL02581:Trank1	APN	9	111,383,125 (GRCm38)	missense	probably benign	0.00
IGL02630:Trank1	APN	9	111,373,075 (GRCm38)	missense	possibly damaging	0.70
IGL02839:Trank1	APN	9	111,364,756 (GRCm38)	missense	probably damaging	1.00
IGL02897:Trank1	APN	9	111,367,517 (GRCm38)	missense	probably damaging	0.99
IGL03065:Trank1	APN	9	111,390,293 (GRCm38)	missense	possibly damaging	0.64
IGL03123:Trank1	APN	9	111,367,407 (GRCm38)	missense	probably damaging	1.00
IGL03143:Trank1	APN	9	111,366,087 (GRCm38)	missense	probably damaging	1.00
IGL03323:Trank1	APN	9	111,352,116 (GRCm38)	missense	probably damaging	1.00
1mM(1):Trank1	UTSW	9	111,392,981 (GRCm38)	missense	probably damaging	1.00
PIT4486001:Trank1	UTSW	9	111,390,107 (GRCm38)	missense	probably damaging	1.00
PIT4812001:Trank1	UTSW	9	111,347,912 (GRCm38)	missense	probably damaging	1.00
R0035:Trank1	UTSW	9	111,366,776 (GRCm38)	missense	probably benign	0.00
R0064:Trank1	UTSW	9	111,343,195 (GRCm38)	missense	probably damaging	1.00
R0064:Trank1	UTSW	9	111,343,195 (GRCm38)	missense	probably damaging	1.00
R0089:Trank1	UTSW	9	111,392,910 (GRCm38)	missense	probably benign	0.00
R0207:Trank1	UTSW	9	111,366,253 (GRCm38)	missense	probably damaging	1.00
R0255:Trank1	UTSW	9	111,366,024 (GRCm38)	missense	possibly damaging	0.92
R0334:Trank1	UTSW	9	111,392,940 (GRCm38)	missense	probably damaging	1.00
R0334:Trank1	UTSW	9	111,365,353 (GRCm38)	missense	probably benign	0.00
R0383:Trank1	UTSW	9	111,391,477 (GRCm38)	missense	probably benign	0.08
R0421:Trank1	UTSW	9	111,391,839 (GRCm38)	missense	probably damaging	1.00
R0494:Trank1	UTSW	9	111,391,293 (GRCm38)	missense	probably benign	0.19
R0518:Trank1	UTSW	9	111,333,808 (GRCm38)	missense	probably damaging	1.00
R0560:Trank1	UTSW	9	111,391,086 (GRCm38)	missense	possibly damaging	0.88
R0637:Trank1	UTSW	9	111,390,441 (GRCm38)	missense	probably damaging	1.00
R0731:Trank1	UTSW	9	111,365,488 (GRCm38)	missense	probably damaging	1.00
R0761:Trank1	UTSW	9	111,366,613 (GRCm38)	missense	probably damaging	1.00
R0766:Trank1	UTSW	9	111,347,469 (GRCm38)	missense	probably benign	0.45
R0827:Trank1	UTSW	9	111,349,417 (GRCm38)	unclassified	probably benign
R1005:Trank1	UTSW	9	111,333,721 (GRCm38)	missense	probably benign	0.13
R1108:Trank1	UTSW	9	111,365,307 (GRCm38)	missense	probably benign	0.00
R1155:Trank1	UTSW	9	111,366,970 (GRCm38)	missense	possibly damaging	0.95
R1470:Trank1	UTSW	9	111,343,232 (GRCm38)	missense	possibly damaging	0.91
R1470:Trank1	UTSW	9	111,343,232 (GRCm38)	missense	possibly damaging	0.91
R1596:Trank1	UTSW	9	111,366,290 (GRCm38)	missense	possibly damaging	0.93
R1601:Trank1	UTSW	9	111,373,477 (GRCm38)	missense	probably damaging	1.00
R1751:Trank1	UTSW	9	111,391,479 (GRCm38)	missense	probably benign
R1754:Trank1	UTSW	9	111,392,871 (GRCm38)	missense	probably benign	0.00
R1767:Trank1	UTSW	9	111,391,479 (GRCm38)	missense	probably benign
R1768:Trank1	UTSW	9	111,392,927 (GRCm38)	missense	probably damaging	0.96
R1809:Trank1	UTSW	9	111,392,825 (GRCm38)	missense	probably benign	0.34
R1912:Trank1	UTSW	9	111,390,709 (GRCm38)	missense	probably benign	0.00
R1920:Trank1	UTSW	9	111,347,928 (GRCm38)	critical splice donor site	probably null
R1960:Trank1	UTSW	9	111,391,628 (GRCm38)	missense	probably damaging	1.00
R1993:Trank1	UTSW	9	111,378,832 (GRCm38)	missense	probably benign	0.20
R2012:Trank1	UTSW	9	111,365,028 (GRCm38)	missense	probably benign
R2025:Trank1	UTSW	9	111,392,039 (GRCm38)	missense	probably benign	0.01
R2050:Trank1	UTSW	9	111,364,788 (GRCm38)	missense	probably damaging	1.00
R2857:Trank1	UTSW	9	111,366,933 (GRCm38)	missense	probably benign	0.00
R2912:Trank1	UTSW	9	111,392,483 (GRCm38)	missense	probably damaging	0.98
R2962:Trank1	UTSW	9	111,352,080 (GRCm38)	missense	probably damaging	1.00
R3030:Trank1	UTSW	9	111,391,530 (GRCm38)	missense	possibly damaging	0.63
R3821:Trank1	UTSW	9	111,378,819 (GRCm38)	missense	probably damaging	1.00
R3822:Trank1	UTSW	9	111,378,819 (GRCm38)	missense	probably damaging	1.00
R3892:Trank1	UTSW	9	111,364,759 (GRCm38)	missense	probably benign	0.03
R4105:Trank1	UTSW	9	111,352,197 (GRCm38)	missense	probably damaging	1.00
R4166:Trank1	UTSW	9	111,373,524 (GRCm38)	nonsense	probably null
R4237:Trank1	UTSW	9	111,367,035 (GRCm38)	missense	probably benign	0.04
R4239:Trank1	UTSW	9	111,367,035 (GRCm38)	missense	probably benign	0.04
R4394:Trank1	UTSW	9	111,365,197 (GRCm38)	missense	possibly damaging	0.86
R4417:Trank1	UTSW	9	111,365,968 (GRCm38)	missense	probably benign	0.17
R4611:Trank1	UTSW	9	111,362,261 (GRCm38)	missense	probably damaging	1.00
R4694:Trank1	UTSW	9	111,392,061 (GRCm38)	missense	probably benign	0.40
R4731:Trank1	UTSW	9	111,390,410 (GRCm38)	missense	probably damaging	1.00
R4843:Trank1	UTSW	9	111,366,078 (GRCm38)	missense	probably benign	0.00
R4852:Trank1	UTSW	9	111,391,895 (GRCm38)	missense	possibly damaging	0.68
R4859:Trank1	UTSW	9	111,365,010 (GRCm38)	missense	probably benign	0.17
R4868:Trank1	UTSW	9	111,365,641 (GRCm38)	missense	probably damaging	1.00
R5080:Trank1	UTSW	9	111,389,221 (GRCm38)	missense	probably damaging	0.99
R5156:Trank1	UTSW	9	111,390,694 (GRCm38)	missense	probably damaging	1.00
R5174:Trank1	UTSW	9	111,365,559 (GRCm38)	missense	probably benign	0.00
R5234:Trank1	UTSW	9	111,386,467 (GRCm38)	missense	probably damaging	1.00
R5386:Trank1	UTSW	9	111,362,402 (GRCm38)	missense	probably benign	0.12
R5419:Trank1	UTSW	9	111,391,301 (GRCm38)	missense	probably damaging	1.00
R5435:Trank1	UTSW	9	111,391,890 (GRCm38)	missense	probably benign	0.00
R5444:Trank1	UTSW	9	111,392,958 (GRCm38)	missense	probably benign	0.04
R5543:Trank1	UTSW	9	111,366,112 (GRCm38)	missense	probably damaging	0.97
R5560:Trank1	UTSW	9	111,390,567 (GRCm38)	missense	probably damaging	1.00
R5772:Trank1	UTSW	9	111,366,676 (GRCm38)	missense	possibly damaging	0.86
R5774:Trank1	UTSW	9	111,391,226 (GRCm38)	missense	probably damaging	1.00
R5843:Trank1	UTSW	9	111,365,860 (GRCm38)	missense	possibly damaging	0.59
R5858:Trank1	UTSW	9	111,392,536 (GRCm38)	missense	probably benign
R5878:Trank1	UTSW	9	111,366,685 (GRCm38)	missense	possibly damaging	0.93
R5900:Trank1	UTSW	9	111,391,716 (GRCm38)	missense	probably damaging	1.00
R5917:Trank1	UTSW	9	111,362,417 (GRCm38)	missense	probably benign	0.38
R5954:Trank1	UTSW	9	111,365,133 (GRCm38)	missense	probably benign	0.13
R6041:Trank1	UTSW	9	111,377,796 (GRCm38)	missense	possibly damaging	0.94
R6112:Trank1	UTSW	9	111,391,737 (GRCm38)	missense	probably damaging	1.00
R6165:Trank1	UTSW	9	111,391,872 (GRCm38)	missense	probably benign	0.00
R6255:Trank1	UTSW	9	111,352,246 (GRCm38)	critical splice donor site	probably null
R6395:Trank1	UTSW	9	111,367,200 (GRCm38)	missense	probably damaging	1.00
R6567:Trank1	UTSW	9	111,347,521 (GRCm38)	missense	probably benign	0.02
R6644:Trank1	UTSW	9	111,364,834 (GRCm38)	missense	possibly damaging	0.85
R6724:Trank1	UTSW	9	111,365,916 (GRCm38)	missense	probably damaging	1.00
R6788:Trank1	UTSW	9	111,390,679 (GRCm38)	missense	probably damaging	1.00
R6831:Trank1	UTSW	9	111,377,899 (GRCm38)	missense	probably benign	0.00
R6934:Trank1	UTSW	9	111,373,090 (GRCm38)	missense	probably damaging	0.99
R7127:Trank1	UTSW	9	111,365,796 (GRCm38)	missense	possibly damaging	0.85
R7206:Trank1	UTSW	9	111,345,515 (GRCm38)	critical splice donor site	probably null
R7236:Trank1	UTSW	9	111,373,074 (GRCm38)	missense	possibly damaging	0.93
R7247:Trank1	UTSW	9	111,367,512 (GRCm38)	missense	probably damaging	1.00
R7292:Trank1	UTSW	9	111,377,870 (GRCm38)	missense	probably benign	0.02
R7431:Trank1	UTSW	9	111,362,402 (GRCm38)	missense	probably benign	0.12
R7448:Trank1	UTSW	9	111,366,349 (GRCm38)	missense	probably benign	0.01
R7477:Trank1	UTSW	9	111,364,957 (GRCm38)	missense	probably benign	0.00
R7514:Trank1	UTSW	9	111,364,756 (GRCm38)	missense	probably damaging	1.00
R7595:Trank1	UTSW	9	111,365,991 (GRCm38)	missense	probably damaging	1.00
R7637:Trank1	UTSW	9	111,365,296 (GRCm38)	missense	possibly damaging	0.71
R7648:Trank1	UTSW	9	111,391,685 (GRCm38)	missense	probably benign
R7737:Trank1	UTSW	9	111,366,012 (GRCm38)	nonsense	probably null
R7784:Trank1	UTSW	9	111,364,103 (GRCm38)	missense	probably damaging	1.00
R7884:Trank1	UTSW	9	111,392,516 (GRCm38)	missense	probably benign
R7912:Trank1	UTSW	9	111,391,528 (GRCm38)	missense	probably benign	0.04
R7938:Trank1	UTSW	9	111,365,028 (GRCm38)	missense	probably benign
R7979:Trank1	UTSW	9	111,377,899 (GRCm38)	missense	probably benign	0.00
R8064:Trank1	UTSW	9	111,352,076 (GRCm38)	nonsense	probably null
R8100:Trank1	UTSW	9	111,392,793 (GRCm38)	missense	probably damaging	1.00
R8124:Trank1	UTSW	9	111,378,927 (GRCm38)	missense	probably benign	0.31
R8198:Trank1	UTSW	9	111,390,812 (GRCm38)	missense	probably benign	0.09
R8219:Trank1	UTSW	9	111,364,909 (GRCm38)	missense	probably damaging	1.00
R8223:Trank1	UTSW	9	111,365,889 (GRCm38)	missense	probably damaging	1.00
R8316:Trank1	UTSW	9	111,349,302 (GRCm38)	missense	probably benign	0.38
R8347:Trank1	UTSW	9	111,367,249 (GRCm38)	missense	probably damaging	1.00
R8436:Trank1	UTSW	9	111,391,382 (GRCm38)	missense	possibly damaging	0.86
R8489:Trank1	UTSW	9	111,390,275 (GRCm38)	missense	probably benign	0.01
R8682:Trank1	UTSW	9	111,365,344 (GRCm38)	missense	probably benign	0.01
R8768:Trank1	UTSW	9	111,389,276 (GRCm38)	missense	probably benign	0.00
R8770:Trank1	UTSW	9	111,390,824 (GRCm38)	missense	probably benign	0.00
R8829:Trank1	UTSW	9	111,347,523 (GRCm38)	missense	probably benign
R8838:Trank1	UTSW	9	111,364,905 (GRCm38)	missense	probably benign	0.03
R8855:Trank1	UTSW	9	111,312,221 (GRCm38)	missense	unknown
R8929:Trank1	UTSW	9	111,378,935 (GRCm38)	missense	possibly damaging	0.93
R9047:Trank1	UTSW	9	111,362,432 (GRCm38)	missense	probably damaging	0.99
R9090:Trank1	UTSW	9	111,345,479 (GRCm38)	missense	probably damaging	1.00
R9114:Trank1	UTSW	9	111,333,775 (GRCm38)	missense	probably damaging	1.00
R9133:Trank1	UTSW	9	111,391,702 (GRCm38)	missense	possibly damaging	0.93
R9177:Trank1	UTSW	9	111,392,511 (GRCm38)	missense	probably benign	0.00
R9178:Trank1	UTSW	9	111,367,200 (GRCm38)	missense	probably damaging	1.00
R9271:Trank1	UTSW	9	111,345,479 (GRCm38)	missense	probably damaging	1.00
R9314:Trank1	UTSW	9	111,365,981 (GRCm38)	missense	probably damaging	1.00
R9373:Trank1	UTSW	9	111,365,191 (GRCm38)	missense	probably benign	0.25
R9380:Trank1	UTSW	9	111,392,670 (GRCm38)	missense	probably benign	0.07
R9435:Trank1	UTSW	9	111,364,822 (GRCm38)	missense	probably benign	0.04
R9501:Trank1	UTSW	9	111,347,875 (GRCm38)	missense	probably benign	0.00
R9593:Trank1	UTSW	9	111,362,297 (GRCm38)	missense	probably benign	0.30
R9601:Trank1	UTSW	9	111,373,125 (GRCm38)	missense	probably benign	0.18
R9729:Trank1	UTSW	9	111,391,469 (GRCm38)	missense	probably damaging	1.00
X0064:Trank1	UTSW	9	111,343,236 (GRCm38)	missense	possibly damaging	0.57
Z1088:Trank1	UTSW	9	111,364,710 (GRCm38)	missense	probably damaging	0.99
Z1177:Trank1	UTSW	9	111,392,870 (GRCm38)	missense	possibly damaging	0.47
Z1177:Trank1	UTSW	9	111,367,377 (GRCm38)	missense	possibly damaging	0.83
Z1177:Trank1	UTSW	9	111,311,902 (GRCm38)	missense	unknown

Predicted Primers

PCR Primer
(F):5'- CAAACAGGGGACAGTGATCC -3'
(R):5'- TTGGGTGAAGTCCTGAATCTCATC -3'

Sequencing Primer
(F):5'- ACAGTGATCCCCGGGTGTATG -3'
(R):5'- TCACCATAAAGCTCATGGATGG -3'

Posted On

2019-06-26