Mutagenetix > Incidental Mutation

Incidental Mutation 'R7310:Trank1'

567515

Institutional Source

Beutler Lab

Gene Symbol

Trank1

Ensembl Gene

ENSMUSG00000062296

Gene Name

tetratricopeptide repeat and ankyrin repeat containing 1

Synonyms

LOC235639, C030048J01Rik, A230061D21Rik, Lba1

MMRRC Submission

045409-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7310 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

111140807-111224843 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 111196194 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Serine at position 1406 (L1406S)

Ref Sequence

ENSEMBL: ENSMUSP00000077697 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000078626]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000078626
AA Change: L1406S

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000077697
Gene: ENSMUSG00000062296
AA Change: L1406S

Domain	Start	End	E-Value	Type
low complexity region	4	30	N/A	INTRINSIC
low complexity region	34	52	N/A	INTRINSIC
low complexity region	113	129	N/A	INTRINSIC
Blast:TPR	144	177	1e-15	BLAST
Blast:TPR	178	209	8e-13	BLAST
Blast:ANK	332	361	1e-6	BLAST
ANK	369	405	5.29e0	SMART
ANK	538	567	2.11e2	SMART
ANK	572	609	7.29e2	SMART
ANK	621	652	1.21e2	SMART
low complexity region	887	895	N/A	INTRINSIC
low complexity region	1152	1172	N/A	INTRINSIC
Blast:AAA	1351	1569	1e-6	BLAST
low complexity region	2166	2177	N/A	INTRINSIC
low complexity region	2395	2411	N/A	INTRINSIC
low complexity region	2636	2649	N/A	INTRINSIC
low complexity region	2966	2983	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.8%

Validation Efficiency

Allele List at MGI

All alleles(2) : Targeted, other(2)

Other mutations in this stock

Total: 86 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2810021J22Rik	A	T	11: 58,771,094 (GRCm39)	Q192L	possibly damaging	Het
Abat	G	A	16: 8,423,457 (GRCm39)	R250Q	probably null	Het
Abcg3	A	C	5: 105,114,632 (GRCm39)	F295C	probably benign	Het
Abl1	T	C	2: 31,690,604 (GRCm39)	S708P	possibly damaging	Het
Acap2	A	T	16: 30,926,972 (GRCm39)	Y489*	probably null	Het
Akr1c6	A	T	13: 4,486,354 (GRCm39)	M54L	probably benign	Het
Arhgap5	A	T	12: 52,589,270 (GRCm39)		probably null	Het
Asap1	A	G	15: 63,971,379 (GRCm39)		probably null	Het
Atrnl1	A	T	19: 57,630,856 (GRCm39)	N208Y	possibly damaging	Het
BC028528	CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT	CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT	3: 95,795,448 (GRCm39)		probably benign	Het
BC028528	GTTCTGTGGTCACTG	GTTCTGTGGTCACTGATTCTGTGGTCACTG	3: 95,795,485 (GRCm39)		probably benign	Het
BC028528	G	GGGGTCACTGGTTCTT	3: 95,795,460 (GRCm39)		probably benign	Het
BC028528	ACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTC	ACTGGTTCTGTGGTCCCTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTC	3: 95,795,451 (GRCm39)		probably benign	Het
Bmi1	T	C	2: 18,689,230 (GRCm39)	S305P	probably benign	Het
Bpifc	T	A	10: 85,798,891 (GRCm39)	I431F	probably damaging	Het
C130050O18Rik	A	T	5: 139,400,993 (GRCm39)	M349L	probably benign	Het
Cacna2d1	A	T	5: 16,519,914 (GRCm39)	D428V	probably damaging	Het
Card14	A	C	11: 119,217,005 (GRCm39)	Q363P	probably null	Het
Cdca2	A	T	14: 67,950,673 (GRCm39)	L86H	probably damaging	Het
Cdh22	G	T	2: 164,954,214 (GRCm39)	S769*	probably null	Het
Cdhr17	A	G	5: 17,075,246 (GRCm39)	Y872C	possibly damaging	Het
Cep164	T	C	9: 45,686,664 (GRCm39)	E690G	probably damaging	Het
Cluh	A	G	11: 74,560,285 (GRCm39)	H1304R	probably benign	Het
Daxx	C	A	17: 34,129,435 (GRCm39)	D5E	possibly damaging	Het
Dnah7c	A	G	1: 46,636,127 (GRCm39)	M1117V	possibly damaging	Het
Entpd3	T	A	9: 120,389,821 (GRCm39)		probably null	Het
Esr1	G	A	10: 4,889,259 (GRCm39)	A386T	probably damaging	Het
Etv5	G	A	16: 22,220,487 (GRCm39)	P300L	probably benign	Het
Exoc3l	A	T	8: 106,020,340 (GRCm39)	L195Q	probably damaging	Het
Exog	T	C	9: 119,274,069 (GRCm39)	L18P	unknown	Het
Fgfr1	T	A	8: 26,052,331 (GRCm39)	V219D	probably benign	Het
Gna14	A	T	19: 16,511,113 (GRCm39)	Q54L		Het
Gnb5	T	C	9: 75,221,570 (GRCm39)	L48P	probably benign	Het
Gpbp1	A	G	13: 111,589,924 (GRCm39)	I57T	probably benign	Het
Hnrnpa1	T	A	15: 103,149,884 (GRCm39)	D48E	probably damaging	Het
Hrc	T	A	7: 44,985,227 (GRCm39)	L126*	probably null	Het
Hspa8	T	G	9: 40,714,704 (GRCm39)	D333E	probably benign	Het
Igsf3	T	A	3: 101,338,895 (GRCm39)	V403D	probably benign	Het
Itga10	C	A	3: 96,555,475 (GRCm39)	A143D	probably damaging	Het
Kdr	T	A	5: 76,104,985 (GRCm39)	I1082F	probably damaging	Het
Klk1b11	A	T	7: 43,428,254 (GRCm39)	I242F	probably damaging	Het
Kng2	G	A	16: 22,806,522 (GRCm39)	T559I	probably benign	Het
Map1b	G	A	13: 99,570,163 (GRCm39)	P853S	unknown	Het
Mmp13	T	C	9: 7,280,880 (GRCm39)	I421T	possibly damaging	Het
Mpeg1	A	T	19: 12,439,615 (GRCm39)	T358S	probably damaging	Het
Msantd5l	A	C	11: 51,145,474 (GRCm39)	W38G	probably damaging	Het
Mttp	T	C	3: 137,800,783 (GRCm39)	D759G	probably damaging	Het
Mup17	T	A	4: 61,511,929 (GRCm39)	Y115F	possibly damaging	Het
Myo1a	G	T	10: 127,541,697 (GRCm39)	A79S	probably damaging	Het
Myo9a	T	A	9: 59,778,436 (GRCm39)	N1397K	probably benign	Het
Nadk2	T	C	15: 9,103,469 (GRCm39)		probably null	Het
Ncf1	A	T	5: 134,250,615 (GRCm39)	S402T	probably benign	Het
Ndufb10	T	C	17: 24,941,188 (GRCm39)	D145G	probably damaging	Het
Nlgn2	G	A	11: 69,721,409 (GRCm39)	T163M	possibly damaging	Het
Nol4	A	T	18: 22,903,801 (GRCm39)	H172Q		Het
Nup205	T	A	6: 35,202,904 (GRCm39)	D1370E	possibly damaging	Het
Or1e32	A	C	11: 73,705,112 (GRCm39)	N265K	probably damaging	Het
Or51ab3	T	A	7: 103,201,892 (GRCm39)	I300N	probably damaging	Het
Or5b97	A	G	19: 12,878,637 (GRCm39)	F169S	probably damaging	Het
Pkd1l2	A	G	8: 117,750,773 (GRCm39)	V1746A	probably benign	Het
Plin2	T	A	4: 86,586,628 (GRCm39)	I68F	probably benign	Het
Proc	A	T	18: 32,268,952 (GRCm39)	M11K	probably benign	Het
Rif1	T	C	2: 51,995,631 (GRCm39)	V950A	probably benign	Het
Rmc1	A	G	18: 12,317,972 (GRCm39)	K362E	probably benign	Het
Rnf208	C	A	2: 25,133,587 (GRCm39)	P94T	probably damaging	Het
Rundc3b	A	T	5: 8,571,011 (GRCm39)	Y269*	probably null	Het
Senp7	T	C	16: 56,006,445 (GRCm39)	V950A	probably benign	Het
Sipa1l1	T	C	12: 82,419,269 (GRCm39)	V649A	probably damaging	Het
Sipa1l3	G	T	7: 29,099,121 (GRCm39)	H383N	probably benign	Het
Slc12a5	G	A	2: 164,834,360 (GRCm39)	V794M	probably damaging	Het
Slc7a7	A	G	14: 54,616,482 (GRCm39)	I200T	probably damaging	Het
Spdye4b	A	C	5: 143,188,103 (GRCm39)	I199L	probably damaging	Het
Styxl2	G	A	1: 165,926,300 (GRCm39)	T1104I	possibly damaging	Het
Tle4	A	T	19: 14,495,155 (GRCm39)	H191Q	probably benign	Het
Tnfsf13b	C	A	8: 10,081,651 (GRCm39)	S271*	probably null	Het
Tnks2	G	A	19: 36,856,839 (GRCm39)	V855I	probably benign	Het
Trhde	T	C	10: 114,636,478 (GRCm39)	E243G	probably damaging	Het
Trim25	A	T	11: 88,906,608 (GRCm39)	N448I	probably benign	Het
Trim31	T	A	17: 37,218,194 (GRCm39)	M308K	probably benign	Het
Ugt2b36	A	T	5: 87,214,138 (GRCm39)	V502E	possibly damaging	Het
Usp10	A	C	8: 120,668,344 (GRCm39)	D215A	possibly damaging	Het
Usp33	T	G	3: 152,066,026 (GRCm39)	L102*	probably null	Het
Wdr12	A	T	1: 60,121,734 (GRCm39)	C272*	probably null	Het
Xndc1	A	C	7: 101,727,938 (GRCm39)		probably null	Het
Zkscan2	T	C	7: 123,089,276 (GRCm39)	I332V	possibly damaging	Het
Zswim5	A	T	4: 116,841,885 (GRCm39)	T822S	probably benign	Het

Other mutations in Trank1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00234:Trank1	APN	9	111,221,677 (GRCm39)	missense	probably damaging	1.00
IGL00467:Trank1	APN	9	111,193,734 (GRCm39)	splice site	probably benign
IGL00569:Trank1	APN	9	111,174,579 (GRCm39)	missense	possibly damaging	0.69
IGL00585:Trank1	APN	9	111,178,358 (GRCm39)	missense	possibly damaging	0.82
IGL01070:Trank1	APN	9	111,195,861 (GRCm39)	missense	probably damaging	1.00
IGL01134:Trank1	APN	9	111,220,849 (GRCm39)	missense	probably benign
IGL01154:Trank1	APN	9	111,215,468 (GRCm39)	missense	probably benign	0.00
IGL01355:Trank1	APN	9	111,194,588 (GRCm39)	missense	possibly damaging	0.94
IGL01407:Trank1	APN	9	111,193,790 (GRCm39)	missense	probably damaging	0.99
IGL01410:Trank1	APN	9	111,194,117 (GRCm39)	missense	probably benign	0.00
IGL01410:Trank1	APN	9	111,194,327 (GRCm39)	missense	probably benign	0.00
IGL01504:Trank1	APN	9	111,202,612 (GRCm39)	missense	probably damaging	1.00
IGL01744:Trank1	APN	9	111,178,431 (GRCm39)	missense	probably damaging	1.00
IGL02043:Trank1	APN	9	111,193,028 (GRCm39)	missense	probably damaging	0.98
IGL02104:Trank1	APN	9	111,219,780 (GRCm39)	missense	possibly damaging	0.85
IGL02193:Trank1	APN	9	111,196,344 (GRCm39)	missense	probably benign	0.43
IGL02581:Trank1	APN	9	111,212,193 (GRCm39)	missense	probably benign	0.00
IGL02630:Trank1	APN	9	111,202,143 (GRCm39)	missense	possibly damaging	0.70
IGL02839:Trank1	APN	9	111,193,824 (GRCm39)	missense	probably damaging	1.00
IGL02897:Trank1	APN	9	111,196,585 (GRCm39)	missense	probably damaging	0.99
IGL03065:Trank1	APN	9	111,219,361 (GRCm39)	missense	possibly damaging	0.64
IGL03123:Trank1	APN	9	111,196,475 (GRCm39)	missense	probably damaging	1.00
IGL03143:Trank1	APN	9	111,195,155 (GRCm39)	missense	probably damaging	1.00
IGL03323:Trank1	APN	9	111,181,184 (GRCm39)	missense	probably damaging	1.00
1mM(1):Trank1	UTSW	9	111,222,049 (GRCm39)	missense	probably damaging	1.00
PIT4486001:Trank1	UTSW	9	111,219,175 (GRCm39)	missense	probably damaging	1.00
PIT4812001:Trank1	UTSW	9	111,176,980 (GRCm39)	missense	probably damaging	1.00
R0035:Trank1	UTSW	9	111,195,844 (GRCm39)	missense	probably benign	0.00
R0064:Trank1	UTSW	9	111,172,263 (GRCm39)	missense	probably damaging	1.00
R0064:Trank1	UTSW	9	111,172,263 (GRCm39)	missense	probably damaging	1.00
R0089:Trank1	UTSW	9	111,221,978 (GRCm39)	missense	probably benign	0.00
R0207:Trank1	UTSW	9	111,195,321 (GRCm39)	missense	probably damaging	1.00
R0255:Trank1	UTSW	9	111,195,092 (GRCm39)	missense	possibly damaging	0.92
R0334:Trank1	UTSW	9	111,222,008 (GRCm39)	missense	probably damaging	1.00
R0334:Trank1	UTSW	9	111,194,421 (GRCm39)	missense	probably benign	0.00
R0383:Trank1	UTSW	9	111,220,545 (GRCm39)	missense	probably benign	0.08
R0421:Trank1	UTSW	9	111,220,907 (GRCm39)	missense	probably damaging	1.00
R0494:Trank1	UTSW	9	111,220,361 (GRCm39)	missense	probably benign	0.19
R0518:Trank1	UTSW	9	111,162,876 (GRCm39)	missense	probably damaging	1.00
R0560:Trank1	UTSW	9	111,220,154 (GRCm39)	missense	possibly damaging	0.88
R0637:Trank1	UTSW	9	111,219,509 (GRCm39)	missense	probably damaging	1.00
R0731:Trank1	UTSW	9	111,194,556 (GRCm39)	missense	probably damaging	1.00
R0761:Trank1	UTSW	9	111,195,681 (GRCm39)	missense	probably damaging	1.00
R0766:Trank1	UTSW	9	111,176,537 (GRCm39)	missense	probably benign	0.45
R0827:Trank1	UTSW	9	111,178,485 (GRCm39)	unclassified	probably benign
R1005:Trank1	UTSW	9	111,162,789 (GRCm39)	missense	probably benign	0.13
R1108:Trank1	UTSW	9	111,194,375 (GRCm39)	missense	probably benign	0.00
R1155:Trank1	UTSW	9	111,196,038 (GRCm39)	missense	possibly damaging	0.95
R1470:Trank1	UTSW	9	111,172,300 (GRCm39)	missense	possibly damaging	0.91
R1470:Trank1	UTSW	9	111,172,300 (GRCm39)	missense	possibly damaging	0.91
R1596:Trank1	UTSW	9	111,195,358 (GRCm39)	missense	possibly damaging	0.93
R1601:Trank1	UTSW	9	111,202,545 (GRCm39)	missense	probably damaging	1.00
R1751:Trank1	UTSW	9	111,220,547 (GRCm39)	missense	probably benign
R1754:Trank1	UTSW	9	111,221,939 (GRCm39)	missense	probably benign	0.00
R1767:Trank1	UTSW	9	111,220,547 (GRCm39)	missense	probably benign
R1768:Trank1	UTSW	9	111,221,995 (GRCm39)	missense	probably damaging	0.96
R1809:Trank1	UTSW	9	111,221,893 (GRCm39)	missense	probably benign	0.34
R1912:Trank1	UTSW	9	111,219,777 (GRCm39)	missense	probably benign	0.00
R1920:Trank1	UTSW	9	111,176,996 (GRCm39)	critical splice donor site	probably null
R1960:Trank1	UTSW	9	111,220,696 (GRCm39)	missense	probably damaging	1.00
R1993:Trank1	UTSW	9	111,207,900 (GRCm39)	missense	probably benign	0.20
R2012:Trank1	UTSW	9	111,194,096 (GRCm39)	missense	probably benign
R2025:Trank1	UTSW	9	111,221,107 (GRCm39)	missense	probably benign	0.01
R2050:Trank1	UTSW	9	111,193,856 (GRCm39)	missense	probably damaging	1.00
R2857:Trank1	UTSW	9	111,196,001 (GRCm39)	missense	probably benign	0.00
R2912:Trank1	UTSW	9	111,221,551 (GRCm39)	missense	probably damaging	0.98
R2962:Trank1	UTSW	9	111,181,148 (GRCm39)	missense	probably damaging	1.00
R3030:Trank1	UTSW	9	111,220,598 (GRCm39)	missense	possibly damaging	0.63
R3821:Trank1	UTSW	9	111,207,887 (GRCm39)	missense	probably damaging	1.00
R3822:Trank1	UTSW	9	111,207,887 (GRCm39)	missense	probably damaging	1.00
R3892:Trank1	UTSW	9	111,193,827 (GRCm39)	missense	probably benign	0.03
R4105:Trank1	UTSW	9	111,181,265 (GRCm39)	missense	probably damaging	1.00
R4166:Trank1	UTSW	9	111,202,592 (GRCm39)	nonsense	probably null
R4237:Trank1	UTSW	9	111,196,103 (GRCm39)	missense	probably benign	0.04
R4239:Trank1	UTSW	9	111,196,103 (GRCm39)	missense	probably benign	0.04
R4394:Trank1	UTSW	9	111,194,265 (GRCm39)	missense	possibly damaging	0.86
R4417:Trank1	UTSW	9	111,195,036 (GRCm39)	missense	probably benign	0.17
R4611:Trank1	UTSW	9	111,191,329 (GRCm39)	missense	probably damaging	1.00
R4694:Trank1	UTSW	9	111,221,129 (GRCm39)	missense	probably benign	0.40
R4731:Trank1	UTSW	9	111,219,478 (GRCm39)	missense	probably damaging	1.00
R4843:Trank1	UTSW	9	111,195,146 (GRCm39)	missense	probably benign	0.00
R4852:Trank1	UTSW	9	111,220,963 (GRCm39)	missense	possibly damaging	0.68
R4859:Trank1	UTSW	9	111,194,078 (GRCm39)	missense	probably benign	0.17
R4868:Trank1	UTSW	9	111,194,709 (GRCm39)	missense	probably damaging	1.00
R5080:Trank1	UTSW	9	111,218,289 (GRCm39)	missense	probably damaging	0.99
R5156:Trank1	UTSW	9	111,219,762 (GRCm39)	missense	probably damaging	1.00
R5174:Trank1	UTSW	9	111,194,627 (GRCm39)	missense	probably benign	0.00
R5234:Trank1	UTSW	9	111,215,535 (GRCm39)	missense	probably damaging	1.00
R5386:Trank1	UTSW	9	111,191,470 (GRCm39)	missense	probably benign	0.12
R5419:Trank1	UTSW	9	111,220,369 (GRCm39)	missense	probably damaging	1.00
R5435:Trank1	UTSW	9	111,220,958 (GRCm39)	missense	probably benign	0.00
R5444:Trank1	UTSW	9	111,222,026 (GRCm39)	missense	probably benign	0.04
R5543:Trank1	UTSW	9	111,195,180 (GRCm39)	missense	probably damaging	0.97
R5560:Trank1	UTSW	9	111,219,635 (GRCm39)	missense	probably damaging	1.00
R5772:Trank1	UTSW	9	111,195,744 (GRCm39)	missense	possibly damaging	0.86
R5774:Trank1	UTSW	9	111,220,294 (GRCm39)	missense	probably damaging	1.00
R5843:Trank1	UTSW	9	111,194,928 (GRCm39)	missense	possibly damaging	0.59
R5858:Trank1	UTSW	9	111,221,604 (GRCm39)	missense	probably benign
R5878:Trank1	UTSW	9	111,195,753 (GRCm39)	missense	possibly damaging	0.93
R5900:Trank1	UTSW	9	111,220,784 (GRCm39)	missense	probably damaging	1.00
R5917:Trank1	UTSW	9	111,191,485 (GRCm39)	missense	probably benign	0.38
R5954:Trank1	UTSW	9	111,194,201 (GRCm39)	missense	probably benign	0.13
R6041:Trank1	UTSW	9	111,206,864 (GRCm39)	missense	possibly damaging	0.94
R6112:Trank1	UTSW	9	111,220,805 (GRCm39)	missense	probably damaging	1.00
R6165:Trank1	UTSW	9	111,220,940 (GRCm39)	missense	probably benign	0.00
R6255:Trank1	UTSW	9	111,181,314 (GRCm39)	critical splice donor site	probably null
R6395:Trank1	UTSW	9	111,196,268 (GRCm39)	missense	probably damaging	1.00
R6567:Trank1	UTSW	9	111,176,589 (GRCm39)	missense	probably benign	0.02
R6644:Trank1	UTSW	9	111,193,902 (GRCm39)	missense	possibly damaging	0.85
R6724:Trank1	UTSW	9	111,194,984 (GRCm39)	missense	probably damaging	1.00
R6788:Trank1	UTSW	9	111,219,747 (GRCm39)	missense	probably damaging	1.00
R6831:Trank1	UTSW	9	111,206,967 (GRCm39)	missense	probably benign	0.00
R6934:Trank1	UTSW	9	111,202,158 (GRCm39)	missense	probably damaging	0.99
R7127:Trank1	UTSW	9	111,194,864 (GRCm39)	missense	possibly damaging	0.85
R7206:Trank1	UTSW	9	111,174,583 (GRCm39)	critical splice donor site	probably null
R7236:Trank1	UTSW	9	111,202,142 (GRCm39)	missense	possibly damaging	0.93
R7247:Trank1	UTSW	9	111,196,580 (GRCm39)	missense	probably damaging	1.00
R7292:Trank1	UTSW	9	111,206,938 (GRCm39)	missense	probably benign	0.02
R7431:Trank1	UTSW	9	111,191,470 (GRCm39)	missense	probably benign	0.12
R7448:Trank1	UTSW	9	111,195,417 (GRCm39)	missense	probably benign	0.01
R7477:Trank1	UTSW	9	111,194,025 (GRCm39)	missense	probably benign	0.00
R7514:Trank1	UTSW	9	111,193,824 (GRCm39)	missense	probably damaging	1.00
R7595:Trank1	UTSW	9	111,195,059 (GRCm39)	missense	probably damaging	1.00
R7637:Trank1	UTSW	9	111,194,364 (GRCm39)	missense	possibly damaging	0.71
R7648:Trank1	UTSW	9	111,220,753 (GRCm39)	missense	probably benign
R7737:Trank1	UTSW	9	111,195,080 (GRCm39)	nonsense	probably null
R7784:Trank1	UTSW	9	111,193,171 (GRCm39)	missense	probably damaging	1.00
R7884:Trank1	UTSW	9	111,221,584 (GRCm39)	missense	probably benign
R7912:Trank1	UTSW	9	111,220,596 (GRCm39)	missense	probably benign	0.04
R7938:Trank1	UTSW	9	111,194,096 (GRCm39)	missense	probably benign
R7979:Trank1	UTSW	9	111,206,967 (GRCm39)	missense	probably benign	0.00
R8064:Trank1	UTSW	9	111,181,144 (GRCm39)	nonsense	probably null
R8100:Trank1	UTSW	9	111,221,861 (GRCm39)	missense	probably damaging	1.00
R8124:Trank1	UTSW	9	111,207,995 (GRCm39)	missense	probably benign	0.31
R8198:Trank1	UTSW	9	111,219,880 (GRCm39)	missense	probably benign	0.09
R8219:Trank1	UTSW	9	111,193,977 (GRCm39)	missense	probably damaging	1.00
R8223:Trank1	UTSW	9	111,194,957 (GRCm39)	missense	probably damaging	1.00
R8316:Trank1	UTSW	9	111,178,370 (GRCm39)	missense	probably benign	0.38
R8347:Trank1	UTSW	9	111,196,317 (GRCm39)	missense	probably damaging	1.00
R8436:Trank1	UTSW	9	111,220,450 (GRCm39)	missense	possibly damaging	0.86
R8489:Trank1	UTSW	9	111,219,343 (GRCm39)	missense	probably benign	0.01
R8682:Trank1	UTSW	9	111,194,412 (GRCm39)	missense	probably benign	0.01
R8768:Trank1	UTSW	9	111,218,344 (GRCm39)	missense	probably benign	0.00
R8770:Trank1	UTSW	9	111,219,892 (GRCm39)	missense	probably benign	0.00
R8829:Trank1	UTSW	9	111,176,591 (GRCm39)	missense	probably benign
R8838:Trank1	UTSW	9	111,193,973 (GRCm39)	missense	probably benign	0.03
R8855:Trank1	UTSW	9	111,141,289 (GRCm39)	missense	unknown
R8929:Trank1	UTSW	9	111,208,003 (GRCm39)	missense	possibly damaging	0.93
R9047:Trank1	UTSW	9	111,191,500 (GRCm39)	missense	probably damaging	0.99
R9090:Trank1	UTSW	9	111,174,547 (GRCm39)	missense	probably damaging	1.00
R9114:Trank1	UTSW	9	111,162,843 (GRCm39)	missense	probably damaging	1.00
R9133:Trank1	UTSW	9	111,220,770 (GRCm39)	missense	possibly damaging	0.93
R9177:Trank1	UTSW	9	111,221,579 (GRCm39)	missense	probably benign	0.00
R9178:Trank1	UTSW	9	111,196,268 (GRCm39)	missense	probably damaging	1.00
R9271:Trank1	UTSW	9	111,174,547 (GRCm39)	missense	probably damaging	1.00
R9314:Trank1	UTSW	9	111,195,049 (GRCm39)	missense	probably damaging	1.00
R9373:Trank1	UTSW	9	111,194,259 (GRCm39)	missense	probably benign	0.25
R9380:Trank1	UTSW	9	111,221,738 (GRCm39)	missense	probably benign	0.07
R9435:Trank1	UTSW	9	111,193,890 (GRCm39)	missense	probably benign	0.04
R9501:Trank1	UTSW	9	111,176,943 (GRCm39)	missense	probably benign	0.00
R9593:Trank1	UTSW	9	111,191,365 (GRCm39)	missense	probably benign	0.30
R9601:Trank1	UTSW	9	111,202,193 (GRCm39)	missense	probably benign	0.18
R9729:Trank1	UTSW	9	111,220,537 (GRCm39)	missense	probably damaging	1.00
X0064:Trank1	UTSW	9	111,172,304 (GRCm39)	missense	possibly damaging	0.57
Z1088:Trank1	UTSW	9	111,193,778 (GRCm39)	missense	probably damaging	0.99
Z1177:Trank1	UTSW	9	111,221,938 (GRCm39)	missense	possibly damaging	0.47
Z1177:Trank1	UTSW	9	111,196,445 (GRCm39)	missense	possibly damaging	0.83
Z1177:Trank1	UTSW	9	111,140,970 (GRCm39)	missense	unknown

Predicted Primers

PCR Primer
(F):5'- CAAACAGGGGACAGTGATCC -3'
(R):5'- TTGGGTGAAGTCCTGAATCTCATC -3'

Sequencing Primer
(F):5'- ACAGTGATCCCCGGGTGTATG -3'
(R):5'- TCACCATAAAGCTCATGGATGG -3'

Posted On

2019-06-26