Incidental Mutation 'R7315:Tnrc6c'
| ID |
567904 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnrc6c
|
| Ensembl Gene |
ENSMUSG00000025571 |
| Gene Name |
trinucleotide repeat containing 6C |
| Synonyms |
9930033H14Rik |
| MMRRC Submission |
045368-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7315 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
117654289-117763439 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 117723528 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 837
(N837K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000115221
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000026658]
[ENSMUST00000106344]
[ENSMUST00000138299]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000026658
AA Change: N997K
PolyPhen 2
Score 0.210 (Sensitivity: 0.92; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000026658
Gene: ENSMUSG00000025571
AA Change: N997K
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
32 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
248 |
257 |
N/A |
INTRINSIC |
|
low complexity region
|
298 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
394 |
408 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
457 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
472 |
573 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
594 |
614 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
632 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
639 |
704 |
5.49e-5 |
PROSPERO |
|
internal_repeat_1
|
799 |
902 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
964 |
981 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
991 |
1051 |
5.49e-5 |
PROSPERO |
|
low complexity region
|
1063 |
1079 |
N/A |
INTRINSIC |
|
low complexity region
|
1111 |
1125 |
N/A |
INTRINSIC |
|
UBA
|
1145 |
1182 |
3.68e-4 |
SMART |
|
Pfam:M_domain
|
1232 |
1459 |
6.8e-77 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1468 |
1646 |
4.1e-75 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1643 |
1722 |
3.7e-33 |
PFAM |
|
RRM
|
1725 |
1792 |
1.81e-2 |
SMART |
|
low complexity region
|
1813 |
1823 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106344
AA Change: N997K
PolyPhen 2
Score 0.210 (Sensitivity: 0.92; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000101951
Gene: ENSMUSG00000025571
AA Change: N997K
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
32 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
248 |
257 |
N/A |
INTRINSIC |
|
low complexity region
|
298 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
394 |
408 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
457 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
472 |
573 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
594 |
614 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
632 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
639 |
704 |
5.49e-5 |
PROSPERO |
|
internal_repeat_1
|
799 |
902 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
964 |
981 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
991 |
1051 |
5.49e-5 |
PROSPERO |
|
low complexity region
|
1063 |
1079 |
N/A |
INTRINSIC |
|
low complexity region
|
1111 |
1125 |
N/A |
INTRINSIC |
|
UBA
|
1145 |
1182 |
3.68e-4 |
SMART |
|
Pfam:M_domain
|
1232 |
1459 |
6.8e-77 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1468 |
1646 |
4.1e-75 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1643 |
1722 |
3.7e-33 |
PFAM |
|
RRM
|
1725 |
1792 |
1.81e-2 |
SMART |
|
low complexity region
|
1813 |
1823 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000138299
AA Change: N837K
PolyPhen 2
Score 0.112 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000115221
Gene: ENSMUSG00000025571
AA Change: N837K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
88 |
97 |
N/A |
INTRINSIC |
|
low complexity region
|
138 |
158 |
N/A |
INTRINSIC |
|
low complexity region
|
234 |
248 |
N/A |
INTRINSIC |
|
low complexity region
|
280 |
297 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
312 |
413 |
9.45e-5 |
PROSPERO |
|
low complexity region
|
434 |
454 |
N/A |
INTRINSIC |
|
low complexity region
|
461 |
472 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
639 |
742 |
9.45e-5 |
PROSPERO |
|
low complexity region
|
804 |
821 |
N/A |
INTRINSIC |
|
low complexity region
|
903 |
919 |
N/A |
INTRINSIC |
|
low complexity region
|
951 |
965 |
N/A |
INTRINSIC |
|
UBA
|
985 |
1022 |
3.68e-4 |
SMART |
|
Pfam:M_domain
|
1036 |
1293 |
1.7e-53 |
PFAM |
|
low complexity region
|
1397 |
1406 |
N/A |
INTRINSIC |
|
PDB:3KTP|B
|
1422 |
1443 |
7e-7 |
PDB |
|
low complexity region
|
1507 |
1518 |
N/A |
INTRINSIC |
|
low complexity region
|
1531 |
1552 |
N/A |
INTRINSIC |
|
RRM
|
1557 |
1624 |
1.81e-2 |
SMART |
|
low complexity region
|
1645 |
1655 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap allele exhibit complete neonatal lethality with cyanosis, respiratory distress and thickened mesenchyme in air sacs. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 74 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca14 |
A |
C |
7: 120,294,118 (GRCm38) |
I1264L |
probably benign |
Het |
| Abcg8 |
C |
A |
17: 84,696,714 (GRCm38) |
D484E |
probably damaging |
Het |
| Abhd13 |
T |
A |
8: 9,987,970 (GRCm38) |
L189H |
probably damaging |
Het |
| Acox2 |
T |
C |
14: 8,256,139 (GRCm38) |
D60G |
probably damaging |
Het |
| Acpp |
A |
G |
9: 104,316,224 (GRCm38) |
|
probably null |
Het |
| Agpat4 |
C |
T |
17: 12,210,298 (GRCm38) |
R146C |
probably damaging |
Het |
| Antxrl |
T |
C |
14: 34,071,547 (GRCm38) |
S411P |
unknown |
Het |
| B4galt5 |
A |
G |
2: 167,301,376 (GRCm38) |
V376A |
probably damaging |
Het |
| BB287469 |
A |
G |
12: 87,819,703 (GRCm38) |
E128G |
unknown |
Het |
| Camk1d |
T |
C |
2: 5,339,230 (GRCm38) |
Y198C |
probably damaging |
Het |
| Cd1d1 |
C |
T |
3: 86,998,113 (GRCm38) |
R191H |
possibly damaging |
Het |
| Cd93 |
A |
G |
2: 148,442,541 (GRCm38) |
V295A |
probably damaging |
Het |
| Cdc27 |
G |
A |
11: 104,515,444 (GRCm38) |
T615I |
possibly damaging |
Het |
| Cfap74 |
T |
C |
4: 155,463,019 (GRCm38) |
Y1221H |
unknown |
Het |
| Col24a1 |
G |
A |
3: 145,431,870 (GRCm38) |
S896N |
possibly damaging |
Het |
| Cst7 |
C |
A |
2: 150,570,583 (GRCm38) |
P22Q |
probably benign |
Het |
| Dnah6 |
C |
T |
6: 73,084,760 (GRCm38) |
A2781T |
probably damaging |
Het |
| Dscaml1 |
G |
A |
9: 45,745,125 (GRCm38) |
A1588T |
probably benign |
Het |
| Dsg2 |
A |
T |
18: 20,579,160 (GRCm38) |
I118F |
probably damaging |
Het |
| Eme2 |
G |
A |
17: 24,894,866 (GRCm38) |
R62W |
probably damaging |
Het |
| Epha3 |
A |
T |
16: 63,552,609 (GRCm38) |
D910E |
probably benign |
Het |
| Ext1 |
T |
C |
15: 53,073,387 (GRCm38) |
D654G |
probably damaging |
Het |
| Fam46b |
C |
T |
4: 133,487,084 (GRCm38) |
T422I |
probably damaging |
Het |
| Fnip2 |
A |
G |
3: 79,506,205 (GRCm38) |
|
probably null |
Het |
| Gon4l |
T |
A |
3: 88,895,179 (GRCm38) |
H1032Q |
probably benign |
Het |
| Ispd |
A |
G |
12: 36,390,374 (GRCm38) |
T94A |
probably benign |
Het |
| Kitl |
G |
A |
10: 100,016,112 (GRCm38) |
R31H |
unknown |
Het |
| Lcp2 |
G |
A |
11: 34,069,906 (GRCm38) |
|
probably null |
Het |
| Lrp2 |
T |
C |
2: 69,491,822 (GRCm38) |
H1921R |
probably damaging |
Het |
| Lvrn |
A |
G |
18: 46,876,984 (GRCm38) |
T400A |
probably benign |
Het |
| Mak16 |
G |
A |
8: 31,164,738 (GRCm38) |
R143* |
probably null |
Het |
| Mettl23 |
A |
G |
11: 116,849,102 (GRCm38) |
I159V |
probably benign |
Het |
| Mr1 |
T |
C |
1: 155,129,290 (GRCm38) |
N335D |
probably benign |
Het |
| Muc2 |
T |
C |
7: 141,690,402 (GRCm38) |
C12R |
probably damaging |
Het |
| Myom1 |
T |
C |
17: 71,080,897 (GRCm38) |
|
probably null |
Het |
| Nav2 |
A |
G |
7: 49,548,289 (GRCm38) |
N33S |
possibly damaging |
Het |
| Ninl |
A |
G |
2: 150,950,050 (GRCm38) |
V851A |
probably benign |
Het |
| Nmt1 |
A |
G |
11: 103,060,183 (GRCm38) |
N367D |
probably benign |
Het |
| Noc2l |
T |
G |
4: 156,241,360 (GRCm38) |
S354R |
probably damaging |
Het |
| Olfr104-ps |
G |
T |
17: 37,362,660 (GRCm38) |
C181F |
probably damaging |
Het |
| Olfr1302 |
T |
C |
2: 111,780,659 (GRCm38) |
V113A |
probably damaging |
Het |
| Olfr151 |
T |
C |
9: 37,730,576 (GRCm38) |
M136V |
probably benign |
Het |
| Olfr198 |
A |
G |
16: 59,202,133 (GRCm38) |
F98L |
probably benign |
Het |
| Olfr293 |
T |
C |
7: 86,664,237 (GRCm38) |
S192P |
probably damaging |
Het |
| Olfr70 |
T |
A |
4: 43,696,961 (GRCm38) |
I71F |
probably damaging |
Het |
| Olfr860 |
G |
T |
9: 19,845,835 (GRCm38) |
S261R |
probably damaging |
Het |
| Olfr877 |
A |
T |
9: 37,855,247 (GRCm38) |
Y143F |
probably benign |
Het |
| Opn1sw |
A |
T |
6: 29,379,363 (GRCm38) |
I214N |
probably damaging |
Het |
| Papss2 |
T |
C |
19: 32,639,225 (GRCm38) |
V217A |
possibly damaging |
Het |
| Pes1 |
A |
G |
11: 3,976,085 (GRCm38) |
I291M |
probably benign |
Het |
| Pqlc2 |
G |
A |
4: 139,301,870 (GRCm38) |
T101M |
probably damaging |
Het |
| Ptprb |
T |
A |
10: 116,362,379 (GRCm38) |
I1660N |
possibly damaging |
Het |
| Rapgef1 |
C |
A |
2: 29,734,492 (GRCm38) |
T1030K |
probably damaging |
Het |
| Rassf8 |
A |
G |
6: 145,815,751 (GRCm38) |
M268V |
probably benign |
Het |
| Rbl2 |
A |
T |
8: 91,076,012 (GRCm38) |
T154S |
probably damaging |
Het |
| Rgs1 |
A |
G |
1: 144,248,899 (GRCm38) |
|
probably null |
Het |
| Rpgrip1 |
C |
T |
14: 52,121,001 (GRCm38) |
T188I |
not run |
Het |
| Rrp1b |
T |
A |
17: 32,058,571 (GRCm38) |
F608L |
probably benign |
Het |
| Sbp |
C |
T |
17: 23,945,306 (GRCm38) |
A154V |
probably benign |
Het |
| Scara3 |
C |
T |
14: 65,931,440 (GRCm38) |
E243K |
probably damaging |
Het |
| Serpinb6b |
A |
T |
13: 32,972,257 (GRCm38) |
D110V |
probably benign |
Het |
| Skiv2l |
T |
A |
17: 34,841,169 (GRCm38) |
D875V |
probably benign |
Het |
| Slc2a4 |
G |
C |
11: 69,946,433 (GRCm38) |
T59R |
probably damaging |
Het |
| Slc4a1 |
A |
G |
11: 102,356,484 (GRCm38) |
S462P |
probably damaging |
Het |
| Snx33 |
C |
T |
9: 56,925,867 (GRCm38) |
R306H |
probably damaging |
Het |
| Srf |
T |
C |
17: 46,551,794 (GRCm38) |
|
probably null |
Het |
| Steap3 |
A |
G |
1: 120,227,912 (GRCm38) |
V439A |
probably benign |
Het |
| Syt10 |
C |
T |
15: 89,814,338 (GRCm38) |
D268N |
probably damaging |
Het |
| Terf2 |
T |
C |
8: 107,081,217 (GRCm38) |
N242S |
probably benign |
Het |
| Tex15 |
A |
G |
8: 33,581,516 (GRCm38) |
T2364A |
probably benign |
Het |
| Tgfbr2 |
A |
T |
9: 116,109,738 (GRCm38) |
H365Q |
possibly damaging |
Het |
| Trim67 |
T |
A |
8: 124,794,330 (GRCm38) |
S144T |
probably benign |
Het |
| Zc3hav1l |
T |
G |
6: 38,295,147 (GRCm38) |
D229A |
possibly damaging |
Het |
| Zmym4 |
A |
T |
4: 126,882,592 (GRCm38) |
V1184E |
probably benign |
Het |
|
| Other mutations in Tnrc6c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00839:Tnrc6c
|
APN |
11 |
117,714,185 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
IGL01013:Tnrc6c
|
APN |
11 |
117,722,029 (GRCm38) |
missense |
probably benign |
0.44 |
|
IGL01092:Tnrc6c
|
APN |
11 |
117,721,985 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01383:Tnrc6c
|
APN |
11 |
117,714,257 (GRCm38) |
missense |
probably benign |
0.37 |
|
IGL01395:Tnrc6c
|
APN |
11 |
117,723,113 (GRCm38) |
missense |
probably benign |
0.08 |
|
IGL01726:Tnrc6c
|
APN |
11 |
117,749,335 (GRCm38) |
splice site |
probably benign |
|
|
IGL01869:Tnrc6c
|
APN |
11 |
117,755,448 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
IGL02108:Tnrc6c
|
APN |
11 |
117,721,199 (GRCm38) |
missense |
probably benign |
0.29 |
|
IGL02457:Tnrc6c
|
APN |
11 |
117,722,977 (GRCm38) |
missense |
probably benign |
0.28 |
|
IGL02612:Tnrc6c
|
APN |
11 |
117,743,000 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
IGL02748:Tnrc6c
|
APN |
11 |
117,732,170 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03160:Tnrc6c
|
APN |
11 |
117,749,825 (GRCm38) |
splice site |
probably benign |
|
|
rodion
|
UTSW |
11 |
117,738,350 (GRCm38) |
critical splice donor site |
probably null |
|
|
F5770:Tnrc6c
|
UTSW |
11 |
117,723,326 (GRCm38) |
missense |
probably damaging |
1.00 |
|
K3955:Tnrc6c
|
UTSW |
11 |
117,760,738 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0015:Tnrc6c
|
UTSW |
11 |
117,721,458 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0143:Tnrc6c
|
UTSW |
11 |
117,752,985 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0277:Tnrc6c
|
UTSW |
11 |
117,739,881 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0323:Tnrc6c
|
UTSW |
11 |
117,739,881 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0464:Tnrc6c
|
UTSW |
11 |
117,760,549 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0699:Tnrc6c
|
UTSW |
11 |
117,722,621 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1015:Tnrc6c
|
UTSW |
11 |
117,721,922 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R1201:Tnrc6c
|
UTSW |
11 |
117,721,674 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1297:Tnrc6c
|
UTSW |
11 |
117,733,703 (GRCm38) |
missense |
possibly damaging |
0.52 |
|
R1560:Tnrc6c
|
UTSW |
11 |
117,759,637 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1596:Tnrc6c
|
UTSW |
11 |
117,758,041 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1758:Tnrc6c
|
UTSW |
11 |
117,760,730 (GRCm38) |
missense |
probably benign |
0.09 |
|
R1892:Tnrc6c
|
UTSW |
11 |
117,714,362 (GRCm38) |
missense |
probably benign |
|
|
R1901:Tnrc6c
|
UTSW |
11 |
117,723,005 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1935:Tnrc6c
|
UTSW |
11 |
117,756,023 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R1936:Tnrc6c
|
UTSW |
11 |
117,756,023 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R1937:Tnrc6c
|
UTSW |
11 |
117,756,023 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R1940:Tnrc6c
|
UTSW |
11 |
117,756,023 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R3622:Tnrc6c
|
UTSW |
11 |
117,749,625 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3711:Tnrc6c
|
UTSW |
11 |
117,723,124 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3725:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3775:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3776:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3836:Tnrc6c
|
UTSW |
11 |
117,723,229 (GRCm38) |
missense |
probably benign |
0.20 |
|
R3844:Tnrc6c
|
UTSW |
11 |
117,755,483 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3852:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3928:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3929:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3937:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3943:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4501:Tnrc6c
|
UTSW |
11 |
117,722,498 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4510:Tnrc6c
|
UTSW |
11 |
117,742,958 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R4511:Tnrc6c
|
UTSW |
11 |
117,742,958 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R4654:Tnrc6c
|
UTSW |
11 |
117,720,971 (GRCm38) |
missense |
probably benign |
|
|
R4765:Tnrc6c
|
UTSW |
11 |
117,742,927 (GRCm38) |
missense |
probably benign |
0.09 |
|
R4824:Tnrc6c
|
UTSW |
11 |
117,722,905 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5004:Tnrc6c
|
UTSW |
11 |
117,721,046 (GRCm38) |
missense |
probably benign |
0.44 |
|
R5094:Tnrc6c
|
UTSW |
11 |
117,721,046 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5130:Tnrc6c
|
UTSW |
11 |
117,738,350 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5234:Tnrc6c
|
UTSW |
11 |
117,760,729 (GRCm38) |
missense |
probably benign |
0.42 |
|
R5235:Tnrc6c
|
UTSW |
11 |
117,760,729 (GRCm38) |
missense |
probably benign |
0.42 |
|
R5345:Tnrc6c
|
UTSW |
11 |
117,723,287 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R5359:Tnrc6c
|
UTSW |
11 |
117,758,905 (GRCm38) |
splice site |
silent |
|
|
R5428:Tnrc6c
|
UTSW |
11 |
117,700,762 (GRCm38) |
start codon destroyed |
probably null |
|
|
R5548:Tnrc6c
|
UTSW |
11 |
117,760,843 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
R5587:Tnrc6c
|
UTSW |
11 |
117,749,271 (GRCm38) |
nonsense |
probably null |
|
|
R5875:Tnrc6c
|
UTSW |
11 |
117,759,708 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5947:Tnrc6c
|
UTSW |
11 |
117,722,519 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6135:Tnrc6c
|
UTSW |
11 |
117,736,005 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R6354:Tnrc6c
|
UTSW |
11 |
117,749,614 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R6389:Tnrc6c
|
UTSW |
11 |
117,722,741 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7027:Tnrc6c
|
UTSW |
11 |
117,733,618 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7048:Tnrc6c
|
UTSW |
11 |
117,721,974 (GRCm38) |
missense |
probably benign |
0.41 |
|
R7098:Tnrc6c
|
UTSW |
11 |
117,714,126 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7378:Tnrc6c
|
UTSW |
11 |
117,741,780 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7386:Tnrc6c
|
UTSW |
11 |
117,721,954 (GRCm38) |
missense |
probably benign |
|
|
R7515:Tnrc6c
|
UTSW |
11 |
117,741,681 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7665:Tnrc6c
|
UTSW |
11 |
117,720,951 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R7755:Tnrc6c
|
UTSW |
11 |
117,758,086 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8679:Tnrc6c
|
UTSW |
11 |
117,714,135 (GRCm38) |
missense |
probably benign |
|
|
R8824:Tnrc6c
|
UTSW |
11 |
117,739,854 (GRCm38) |
splice site |
probably benign |
|
|
R8971:Tnrc6c
|
UTSW |
11 |
117,749,263 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R9261:Tnrc6c
|
UTSW |
11 |
117,714,279 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9283:Tnrc6c
|
UTSW |
11 |
117,700,804 (GRCm38) |
missense |
unknown |
|
|
R9342:Tnrc6c
|
UTSW |
11 |
117,739,894 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9633:Tnrc6c
|
UTSW |
11 |
117,747,183 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9761:Tnrc6c
|
UTSW |
11 |
117,732,310 (GRCm38) |
missense |
probably benign |
|
|
V7580:Tnrc6c
|
UTSW |
11 |
117,723,326 (GRCm38) |
missense |
probably damaging |
1.00 |
|
V7581:Tnrc6c
|
UTSW |
11 |
117,723,326 (GRCm38) |
missense |
probably damaging |
1.00 |
|
V7582:Tnrc6c
|
UTSW |
11 |
117,723,326 (GRCm38) |
missense |
probably damaging |
1.00 |
|
V7583:Tnrc6c
|
UTSW |
11 |
117,723,326 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Tnrc6c
|
UTSW |
11 |
117,732,177 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGATGGTACCTCAGCTTGGG -3'
(R):5'- CCTCACTGTTGGAAGCATGATG -3'
Sequencing Primer
(F):5'- ATCCAGTCATCCAGAGCA -3'
(R):5'- TGGCAGTACTGAGCACACC -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation