Incidental Mutation 'R7320:Slmap'
| ID |
568164 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Slmap
|
| Ensembl Gene |
ENSMUSG00000021870 |
| Gene Name |
sarcolemma associated protein |
| Synonyms |
Slap, D330001L02Rik, Miranda |
| MMRRC Submission |
045370-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7320 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
14 |
| Chromosomal Location |
26134323-26256086 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 26181227 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 369
(F369L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000117816
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038522]
[ENSMUST00000090359]
[ENSMUST00000102956]
[ENSMUST00000112330]
[ENSMUST00000112331]
[ENSMUST00000139075]
|
| AlphaFold |
Q3URD3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000038522
AA Change: F369L
PolyPhen 2
Score 0.393 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000046956
Gene: ENSMUSG00000021870
AA Change: F369L
| Domain | Start | End | E-Value | Type |
|---|
|
FHA
|
27 |
85 |
1.05e-8 |
SMART |
|
coiled coil region
|
167 |
199 |
N/A |
INTRINSIC |
|
coiled coil region
|
230 |
390 |
N/A |
INTRINSIC |
|
coiled coil region
|
486 |
568 |
N/A |
INTRINSIC |
|
coiled coil region
|
595 |
794 |
N/A |
INTRINSIC |
|
transmembrane domain
|
796 |
818 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000090359
AA Change: F369L
PolyPhen 2
Score 0.845 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000087836
Gene: ENSMUSG00000021870
AA Change: F369L
| Domain | Start | End | E-Value | Type |
|---|
|
FHA
|
27 |
85 |
1.05e-8 |
SMART |
|
coiled coil region
|
167 |
199 |
N/A |
INTRINSIC |
|
coiled coil region
|
230 |
390 |
N/A |
INTRINSIC |
|
coiled coil region
|
490 |
572 |
N/A |
INTRINSIC |
|
coiled coil region
|
599 |
799 |
N/A |
INTRINSIC |
|
transmembrane domain
|
801 |
823 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102956
AA Change: F369L
PolyPhen 2
Score 0.393 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000100021
Gene: ENSMUSG00000021870
AA Change: F369L
| Domain | Start | End | E-Value | Type |
|---|
|
FHA
|
27 |
85 |
1.05e-8 |
SMART |
|
coiled coil region
|
167 |
199 |
N/A |
INTRINSIC |
|
coiled coil region
|
230 |
390 |
N/A |
INTRINSIC |
|
coiled coil region
|
486 |
568 |
N/A |
INTRINSIC |
|
coiled coil region
|
595 |
794 |
N/A |
INTRINSIC |
|
transmembrane domain
|
796 |
818 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000112330
AA Change: F369L
PolyPhen 2
Score 0.644 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000107949
Gene: ENSMUSG00000021870
AA Change: F369L
| Domain | Start | End | E-Value | Type |
|---|
|
FHA
|
27 |
85 |
1.05e-8 |
SMART |
|
coiled coil region
|
167 |
199 |
N/A |
INTRINSIC |
|
coiled coil region
|
230 |
383 |
N/A |
INTRINSIC |
|
coiled coil region
|
452 |
534 |
N/A |
INTRINSIC |
|
coiled coil region
|
561 |
761 |
N/A |
INTRINSIC |
|
transmembrane domain
|
763 |
785 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000112331
AA Change: F248L
PolyPhen 2
Score 0.766 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000107950
Gene: ENSMUSG00000021870
AA Change: F248L
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
46 |
78 |
N/A |
INTRINSIC |
|
coiled coil region
|
109 |
260 |
N/A |
INTRINSIC |
|
coiled coil region
|
352 |
434 |
N/A |
INTRINSIC |
|
coiled coil region
|
461 |
661 |
N/A |
INTRINSIC |
|
transmembrane domain
|
663 |
685 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000139075
AA Change: F369L
PolyPhen 2
Score 0.532 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000117816
Gene: ENSMUSG00000021870
AA Change: F369L
| Domain | Start | End | E-Value | Type |
|---|
|
FHA
|
27 |
85 |
1.05e-8 |
SMART |
|
coiled coil region
|
167 |
199 |
N/A |
INTRINSIC |
|
coiled coil region
|
230 |
390 |
N/A |
INTRINSIC |
|
coiled coil region
|
507 |
589 |
N/A |
INTRINSIC |
|
coiled coil region
|
616 |
816 |
N/A |
INTRINSIC |
|
transmembrane domain
|
818 |
840 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000123072
Gene: ENSMUSG00000021870
AA Change: F34L
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
52 |
N/A |
INTRINSIC |
|
coiled coil region
|
97 |
179 |
N/A |
INTRINSIC |
|
coiled coil region
|
206 |
405 |
N/A |
INTRINSIC |
|
transmembrane domain
|
408 |
430 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000117276
Gene: ENSMUSG00000021870
AA Change: F38L
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
59 |
N/A |
INTRINSIC |
|
coiled coil region
|
138 |
220 |
N/A |
INTRINSIC |
|
coiled coil region
|
247 |
447 |
N/A |
INTRINSIC |
|
transmembrane domain
|
450 |
472 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000123344
Gene: ENSMUSG00000021870
AA Change: F132L
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
17 |
142 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a component of a conserved striatin-interacting phosphatase and kinase complex. Striatin family complexes participate in a variety of cellular processes including signaling, cell cycle control, cell migration, Golgi assembly, and apoptosis. The protein encoded by this gene is a coiled-coil, tail-anchored membrane protein with a single C-terminal transmembrane domain that is posttranslationally inserted into membranes. Mutations in this gene are associated with Brugada syndrome, a cardiac channelopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
PHENOTYPE: Homozygous inactivation in this locus affects T cell development. Mice homozygous for a transposon induced allele exhibit cleft palate. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc3 |
A |
G |
11: 94,258,471 (GRCm39) |
I458T |
probably benign |
Het |
| Adam29 |
A |
G |
8: 56,325,749 (GRCm39) |
I235T |
possibly damaging |
Het |
| Afap1 |
G |
A |
5: 36,105,567 (GRCm39) |
V174I |
probably damaging |
Het |
| Ak8 |
A |
T |
2: 28,703,004 (GRCm39) |
D456V |
probably damaging |
Het |
| Alb |
T |
C |
5: 90,612,846 (GRCm39) |
|
probably null |
Het |
| Alox12 |
C |
T |
11: 70,145,298 (GRCm39) |
A92T |
probably benign |
Het |
| Arhgap23 |
T |
C |
11: 97,342,371 (GRCm39) |
S218P |
probably benign |
Het |
| Blm |
G |
A |
7: 80,105,102 (GRCm39) |
Q1389* |
probably null |
Het |
| C1ql4 |
A |
T |
15: 98,985,605 (GRCm39) |
V2E |
unknown |
Het |
| Casp12 |
A |
G |
9: 5,348,897 (GRCm39) |
|
probably null |
Het |
| Ccdc73 |
A |
T |
2: 104,829,521 (GRCm39) |
I1065F |
possibly damaging |
Het |
| Ccdc83 |
C |
T |
7: 89,873,242 (GRCm39) |
G371D |
probably damaging |
Het |
| Cfap65 |
A |
G |
1: 74,965,763 (GRCm39) |
S416P |
probably damaging |
Het |
| Cftr |
T |
A |
6: 18,319,012 (GRCm39) |
C1351S |
probably damaging |
Het |
| Clcn4 |
A |
T |
7: 7,294,827 (GRCm39) |
H311Q |
probably benign |
Het |
| Cldn13 |
T |
G |
5: 134,943,874 (GRCm39) |
I104L |
probably benign |
Het |
| Cul9 |
A |
G |
17: 46,821,835 (GRCm39) |
V1880A |
possibly damaging |
Het |
| Ddx17 |
A |
T |
15: 79,416,105 (GRCm39) |
D407E |
probably damaging |
Het |
| Ddx28 |
G |
A |
8: 106,737,957 (GRCm39) |
P34S |
probably damaging |
Het |
| Dnah5 |
A |
T |
15: 28,270,616 (GRCm39) |
N973Y |
probably null |
Het |
| Dnai4 |
A |
T |
4: 102,907,384 (GRCm39) |
I634N |
possibly damaging |
Het |
| Dock10 |
A |
G |
1: 80,527,421 (GRCm39) |
|
probably null |
Het |
| Dock3 |
T |
C |
9: 106,772,723 (GRCm39) |
D510G |
probably benign |
Het |
| Dst |
T |
A |
1: 34,230,175 (GRCm39) |
D2589E |
probably benign |
Het |
| E2f7 |
T |
C |
10: 110,599,991 (GRCm39) |
Y249H |
not run |
Het |
| Eef2kmt |
T |
C |
16: 5,068,373 (GRCm39) |
Y69C |
possibly damaging |
Het |
| Elapor1 |
T |
A |
3: 108,371,619 (GRCm39) |
K650* |
probably null |
Het |
| Erlin1 |
T |
C |
19: 44,047,504 (GRCm39) |
Y139C |
probably damaging |
Het |
| Exog |
G |
T |
9: 119,291,544 (GRCm39) |
V274L |
possibly damaging |
Het |
| Fam83e |
G |
A |
7: 45,371,896 (GRCm39) |
V98M |
probably benign |
Het |
| Fras1 |
C |
T |
5: 96,857,745 (GRCm39) |
T2013I |
probably benign |
Het |
| Gart |
G |
T |
16: 91,418,569 (GRCm39) |
A970E |
probably benign |
Het |
| Gga2 |
T |
A |
7: 121,601,326 (GRCm39) |
H259L |
probably benign |
Het |
| Glis3 |
C |
A |
19: 28,508,998 (GRCm39) |
V329F |
probably damaging |
Het |
| Gm6356 |
T |
A |
14: 6,972,923 (GRCm38) |
N53I |
probably damaging |
Het |
| Golgb1 |
C |
A |
16: 36,736,313 (GRCm39) |
C1894* |
probably null |
Het |
| Ifi203 |
T |
C |
1: 173,756,733 (GRCm39) |
N350S |
unknown |
Het |
| Isy1 |
T |
A |
6: 87,810,688 (GRCm39) |
R55S |
unknown |
Het |
| Itsn1 |
A |
T |
16: 91,636,587 (GRCm39) |
D678V |
unknown |
Het |
| Lhcgr |
T |
A |
17: 89,049,506 (GRCm39) |
R673S |
probably benign |
Het |
| Lnx2 |
C |
A |
5: 146,956,943 (GRCm39) |
R601L |
possibly damaging |
Het |
| Map4 |
A |
G |
9: 109,910,585 (GRCm39) |
T1093A |
probably benign |
Het |
| Minar1 |
A |
G |
9: 89,483,679 (GRCm39) |
S573P |
probably benign |
Het |
| Mink1 |
A |
G |
11: 70,489,899 (GRCm39) |
K92E |
probably benign |
Het |
| Moxd1 |
A |
G |
10: 24,177,363 (GRCm39) |
I560V |
probably benign |
Het |
| Mrc2 |
C |
A |
11: 105,220,061 (GRCm39) |
D327E |
possibly damaging |
Het |
| Notch2 |
A |
G |
3: 98,038,643 (GRCm39) |
E1262G |
possibly damaging |
Het |
| Or2g1 |
T |
A |
17: 38,107,248 (GRCm39) |
N304K |
probably benign |
Het |
| Or4k48 |
A |
G |
2: 111,476,297 (GRCm39) |
L15S |
probably benign |
Het |
| Or52d3 |
C |
A |
7: 104,229,645 (GRCm39) |
S264* |
probably null |
Het |
| Or5an1 |
G |
A |
19: 12,261,180 (GRCm39) |
G256D |
possibly damaging |
Het |
| Or5b120 |
T |
A |
19: 13,480,544 (GRCm39) |
M279K |
possibly damaging |
Het |
| Or5j3 |
GTACTTTTT |
GT |
2: 86,128,338 (GRCm39) |
|
probably null |
Het |
| Or5m13 |
A |
T |
2: 85,748,718 (GRCm39) |
I150F |
probably benign |
Het |
| Or6c5b |
A |
T |
10: 129,245,654 (GRCm39) |
T140S |
possibly damaging |
Het |
| Pcbp2 |
T |
A |
15: 102,381,782 (GRCm39) |
V5E |
probably damaging |
Het |
| Pcp4l1 |
G |
A |
1: 171,002,034 (GRCm39) |
A42V |
possibly damaging |
Het |
| Pgghg |
A |
T |
7: 140,522,953 (GRCm39) |
Y104F |
probably benign |
Het |
| Plscr2 |
T |
C |
9: 92,173,193 (GRCm39) |
|
probably null |
Het |
| Ppfibp1 |
C |
T |
6: 146,879,551 (GRCm39) |
A25V |
probably damaging |
Het |
| Ptgfr |
C |
T |
3: 151,541,034 (GRCm39) |
G158D |
probably benign |
Het |
| Ptgs2 |
T |
C |
1: 149,978,446 (GRCm39) |
F186S |
probably damaging |
Het |
| Ptpn14 |
A |
G |
1: 189,564,956 (GRCm39) |
E181G |
probably benign |
Het |
| Rpgrip1 |
A |
G |
14: 52,368,673 (GRCm39) |
K291E |
possibly damaging |
Het |
| Rtn4rl1 |
T |
C |
11: 75,085,122 (GRCm39) |
|
probably null |
Het |
| Sema3b |
T |
A |
9: 107,478,141 (GRCm39) |
M415L |
probably benign |
Het |
| Sh3bp4 |
A |
G |
1: 89,073,216 (GRCm39) |
E688G |
probably damaging |
Het |
| Slco6c1 |
G |
A |
1: 97,055,887 (GRCm39) |
R5C |
possibly damaging |
Het |
| Sphk2 |
T |
C |
7: 45,361,894 (GRCm39) |
N181S |
possibly damaging |
Het |
| Sqor |
A |
G |
2: 122,641,730 (GRCm39) |
T235A |
probably benign |
Het |
| St13 |
A |
G |
15: 81,273,854 (GRCm39) |
L80P |
probably damaging |
Het |
| St3gal6 |
A |
G |
16: 58,314,074 (GRCm39) |
Y20H |
probably benign |
Het |
| Sun1 |
T |
G |
5: 139,234,239 (GRCm39) |
Y899D |
probably damaging |
Het |
| Synm |
C |
T |
7: 67,385,128 (GRCm39) |
E845K |
possibly damaging |
Het |
| Tg |
A |
T |
15: 66,566,633 (GRCm39) |
D1227V |
possibly damaging |
Het |
| Thbs1 |
A |
G |
2: 117,945,438 (GRCm39) |
N306D |
possibly damaging |
Het |
| Tmcc3 |
A |
T |
10: 94,414,357 (GRCm39) |
N51Y |
possibly damaging |
Het |
| Usp4 |
A |
G |
9: 108,265,505 (GRCm39) |
D856G |
probably benign |
Het |
| Vil1 |
G |
A |
1: 74,457,603 (GRCm39) |
A79T |
probably damaging |
Het |
| Vmn1r119 |
T |
A |
7: 20,746,271 (GRCm39) |
H37L |
probably damaging |
Het |
| Vmn2r110 |
A |
T |
17: 20,816,316 (GRCm39) |
M69K |
probably benign |
Het |
| Ywhaq |
A |
G |
12: 21,444,982 (GRCm39) |
L221P |
probably damaging |
Het |
| Zfp142 |
G |
A |
1: 74,609,167 (GRCm39) |
Q1543* |
probably null |
Het |
| Zfp384 |
T |
A |
6: 125,001,793 (GRCm39) |
M146K |
possibly damaging |
Het |
|
| Other mutations in Slmap |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02402:Slmap
|
APN |
14 |
26,184,865 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02612:Slmap
|
APN |
14 |
26,180,621 (GRCm39) |
splice site |
probably benign |
|
|
IGL02630:Slmap
|
APN |
14 |
26,143,586 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02798:Slmap
|
APN |
14 |
26,191,533 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
PIT4382001:Slmap
|
UTSW |
14 |
26,254,586 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0433:Slmap
|
UTSW |
14 |
26,174,749 (GRCm39) |
nonsense |
probably null |
|
|
R0963:Slmap
|
UTSW |
14 |
26,189,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1721:Slmap
|
UTSW |
14 |
26,181,373 (GRCm39) |
splice site |
probably benign |
|
|
R1848:Slmap
|
UTSW |
14 |
26,143,729 (GRCm39) |
missense |
probably benign |
|
|
R2151:Slmap
|
UTSW |
14 |
26,139,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2152:Slmap
|
UTSW |
14 |
26,139,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2153:Slmap
|
UTSW |
14 |
26,139,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2154:Slmap
|
UTSW |
14 |
26,139,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3725:Slmap
|
UTSW |
14 |
26,148,397 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3726:Slmap
|
UTSW |
14 |
26,148,397 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3935:Slmap
|
UTSW |
14 |
26,180,570 (GRCm39) |
missense |
probably benign |
|
|
R4118:Slmap
|
UTSW |
14 |
26,204,027 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4594:Slmap
|
UTSW |
14 |
26,186,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4731:Slmap
|
UTSW |
14 |
26,189,690 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4732:Slmap
|
UTSW |
14 |
26,189,690 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4733:Slmap
|
UTSW |
14 |
26,189,690 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4817:Slmap
|
UTSW |
14 |
26,183,507 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4847:Slmap
|
UTSW |
14 |
26,147,763 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4860:Slmap
|
UTSW |
14 |
26,181,364 (GRCm39) |
missense |
probably benign |
0.22 |
|
R4860:Slmap
|
UTSW |
14 |
26,181,364 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5092:Slmap
|
UTSW |
14 |
26,184,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5211:Slmap
|
UTSW |
14 |
26,204,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5387:Slmap
|
UTSW |
14 |
26,181,088 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5821:Slmap
|
UTSW |
14 |
26,183,435 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6404:Slmap
|
UTSW |
14 |
26,143,566 (GRCm39) |
splice site |
probably null |
|
|
R6856:Slmap
|
UTSW |
14 |
26,151,247 (GRCm39) |
splice site |
probably null |
|
|
R6977:Slmap
|
UTSW |
14 |
26,254,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7108:Slmap
|
UTSW |
14 |
26,143,676 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7470:Slmap
|
UTSW |
14 |
26,148,575 (GRCm39) |
missense |
probably benign |
|
|
R7520:Slmap
|
UTSW |
14 |
26,148,575 (GRCm39) |
missense |
probably benign |
|
|
R7540:Slmap
|
UTSW |
14 |
26,181,346 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7544:Slmap
|
UTSW |
14 |
26,151,003 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7544:Slmap
|
UTSW |
14 |
26,151,001 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8112:Slmap
|
UTSW |
14 |
26,143,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8153:Slmap
|
UTSW |
14 |
26,254,488 (GRCm39) |
missense |
probably benign |
|
|
R8196:Slmap
|
UTSW |
14 |
26,189,646 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8300:Slmap
|
UTSW |
14 |
26,139,374 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R8523:Slmap
|
UTSW |
14 |
26,150,965 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9039:Slmap
|
UTSW |
14 |
26,254,519 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9094:Slmap
|
UTSW |
14 |
26,137,355 (GRCm39) |
intron |
probably benign |
|
|
R9504:Slmap
|
UTSW |
14 |
26,136,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Slmap
|
UTSW |
14 |
26,151,013 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9695:Slmap
|
UTSW |
14 |
26,183,496 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9763:Slmap
|
UTSW |
14 |
26,204,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9801:Slmap
|
UTSW |
14 |
26,143,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Slmap
|
UTSW |
14 |
26,254,605 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GTGACACCTACCTAAGCTGC -3'
(R):5'- AAATGAATGGGGTCAGTTCTGG -3'
Sequencing Primer
(F):5'- ACCTAAGCTGCTGCATTCTTTAAGG -3'
(R):5'- CTGGCTTTCAGCTAGCTAAAGCAAG -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation