Mutagenetix > Incidental Mutation

Incidental Mutation 'R7323:Dnah1'

568308

Institutional Source

Beutler Lab

Gene Symbol

Dnah1

Ensembl Gene

ENSMUSG00000019027

Gene Name

dynein, axonemal, heavy chain 1

Synonyms

MDHC7, B230373P09Rik, ferf1, G1-415-19, E030034C22Rik, Dnahc1

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7323 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

30982332-31045853 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 31020664 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Threonine at position 1235 (I1235T)

Ref Sequence

ENSEMBL: ENSMUSP00000043281 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000048603]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000048603
AA Change: I1235T

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000043281
Gene: ENSMUSG00000019027
AA Change: I1235T

Domain	Start	End	E-Value	Type
low complexity region	43	59	N/A	INTRINSIC
Pfam:DHC_N2	998	1404	6.3e-146	PFAM
AAA	1558	1697	6.02e-1	SMART
AAA	1839	2077	4.66e0	SMART
low complexity region	2149	2157	N/A	INTRINSIC
AAA	2204	2353	2.35e-1	SMART
Pfam:AAA_8	2533	2803	7.7e-84	PFAM
Pfam:MT	2815	3165	9.9e-57	PFAM
Pfam:AAA_9	3185	3410	1.1e-93	PFAM
Pfam:Dynein_heavy	3545	4246	2.7e-275	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.8%

Validation Efficiency

100% (73/73)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes an inner dynein arm heavy chain that provides structural support between the radial spokes and the outer doublet of the sperm tail. Naturally occurring mutations in this gene are associated with primary ciliary dyskinesia and multiple morphological anomalies of the flagella that result in asthenozoospermia and male infertility. Mice with a homozygous knockout of the orthologous gene are viable but have reduced sperm motility and are infertile. [provided by RefSeq, Feb 2017]
PHENOTYPE: Homozygous mutants are male sterile, and show impaired ciliary and flagellar motility that is also observed in the tracheal cilia. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 72 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930524J08Rik	C	A	5: 100,126,945 (GRCm39)	A9E	unknown	Het
6030452D12Rik	A	T	8: 107,227,411 (GRCm39)		probably null	Het
Abcb11	C	A	2: 69,117,979 (GRCm39)	Q466H	probably damaging	Het
Adam20	A	G	8: 41,248,421 (GRCm39)	D177G	probably benign	Het
Ampd1	A	T	3: 102,992,696 (GRCm39)	Q150L	probably benign	Het
Angpt2	A	C	8: 18,755,840 (GRCm39)	M209R	probably benign	Het
Aoc2	G	A	11: 101,219,371 (GRCm39)	R598Q	probably damaging	Het
Arap1	A	G	7: 101,049,418 (GRCm39)	D960G	probably damaging	Het
Bhlhe40	G	C	6: 108,642,242 (GRCm39)	L395F	probably benign	Het
Cacna1i	T	C	15: 80,275,854 (GRCm39)	C1882R	possibly damaging	Het
Ccr6	A	G	17: 8,475,611 (GRCm39)	N272S	possibly damaging	Het
Ces1f	A	T	8: 93,998,472 (GRCm39)	W175R	probably damaging	Het
Ces3a	A	C	8: 105,782,239 (GRCm39)	H364P	possibly damaging	Het
Cfap54	T	C	10: 92,637,000 (GRCm39)	M3130V	probably benign	Het
Clca3b	G	A	3: 144,531,681 (GRCm39)	P708S	possibly damaging	Het
Cps1	A	T	1: 67,197,028 (GRCm39)	T360S	probably benign	Het
Cramp1	A	T	17: 25,201,379 (GRCm39)	M701K	possibly damaging	Het
Efcab3	T	C	11: 104,920,837 (GRCm39)	L4676P	probably benign	Het
Ergic1	A	G	17: 26,860,644 (GRCm39)	E244G	probably damaging	Het
Fignl2	C	A	15: 100,951,382 (GRCm39)	R300L	unknown	Het
Fry	T	C	5: 150,419,814 (GRCm39)	M628T		Het
Fscn3	A	G	6: 28,431,544 (GRCm39)	T292A	possibly damaging	Het
Fsip2	A	T	2: 82,819,860 (GRCm39)	I5198L	probably benign	Het
Gm4181	T	A	14: 51,869,990 (GRCm39)	R104W	probably damaging	Het
Gnl1	G	A	17: 36,294,305 (GRCm39)	R308H	probably benign	Het
Gtf2h4	G	T	17: 35,980,857 (GRCm39)	L271I	probably damaging	Het
Helq	GTTT	GTT	5: 100,931,051 (GRCm39)		probably null	Het
Hhatl	A	T	9: 121,618,652 (GRCm39)	W117R	probably benign	Het
Hlx	A	G	1: 184,462,993 (GRCm39)	F220L	probably benign	Het
Il31ra	T	C	13: 112,688,497 (GRCm39)	I27V	probably damaging	Het
Itga8	T	G	2: 12,266,940 (GRCm39)	D165A	probably damaging	Het
Krt33a	A	C	11: 99,902,801 (GRCm39)	V341G	probably benign	Het
Lrrc3c	A	G	11: 98,490,266 (GRCm39)	M208V	possibly damaging	Het
Mapk8ip3	A	T	17: 25,120,135 (GRCm39)	S947T	probably benign	Het
Muc5b	A	G	7: 141,412,444 (GRCm39)	I1797V	unknown	Het
Myh2	A	T	11: 67,088,191 (GRCm39)	T1936S	probably benign	Het
Nr1h2	T	C	7: 44,199,746 (GRCm39)	Y391C	possibly damaging	Het
Or1l8	T	A	2: 36,817,986 (GRCm39)	I47F	probably damaging	Het
Or4c114	A	T	2: 88,904,811 (GRCm39)	I208K	probably damaging	Het
Or4e2	A	G	14: 52,688,670 (GRCm39)	I267V	probably benign	Het
Or5d40	A	G	2: 88,015,952 (GRCm39)	T244A	possibly damaging	Het
Phf3	A	G	1: 30,852,211 (GRCm39)	M1064T	probably benign	Het
Pkd1	A	G	17: 24,794,025 (GRCm39)	E1904G	probably benign	Het
Polrmt	A	G	10: 79,576,483 (GRCm39)	V491A	probably benign	Het
Ppm1j	C	A	3: 104,691,429 (GRCm39)	R306S	probably damaging	Het
Prkd2	T	C	7: 16,581,547 (GRCm39)	F134S	probably benign	Het
Prpf8	C	A	11: 75,382,610 (GRCm39)	Q439K	probably benign	Het
Prss50	A	T	9: 110,692,800 (GRCm39)	I307F	possibly damaging	Het
Rgs20	A	G	1: 4,982,535 (GRCm39)		probably null	Het
Rnf144b	A	G	13: 47,393,258 (GRCm39)	E199G	probably damaging	Het
Slc12a4	C	T	8: 106,682,347 (GRCm39)	G121S	probably damaging	Het
Slc22a26	A	T	19: 7,768,259 (GRCm39)	V233E	probably damaging	Het
Slc27a2	T	G	2: 126,395,124 (GRCm39)	L17R	probably benign	Het
Slc6a17	A	G	3: 107,398,794 (GRCm39)	V269A	probably benign	Het
Srp54c	T	C	12: 55,304,237 (GRCm39)	V395A	probably benign	Het
Sspo	A	T	6: 48,438,581 (GRCm39)	S1550C	possibly damaging	Het
Tet1	A	G	10: 62,715,818 (GRCm39)		probably benign	Het
Themis	A	T	10: 28,609,497 (GRCm39)	H88L	probably benign	Het
Tmem63b	G	A	17: 45,971,773 (GRCm39)	T814M	possibly damaging	Het
Tnc	G	A	4: 63,889,469 (GRCm39)	T1679I	probably damaging	Het
Tnfrsf11a	A	G	1: 105,772,456 (GRCm39)	D581G	probably damaging	Het
Trim30d	A	C	7: 104,132,555 (GRCm39)	V244G	probably benign	Het
Trpv1	T	C	11: 73,151,163 (GRCm39)	S784P	possibly damaging	Het
Tulp1	G	A	17: 28,575,398 (GRCm39)	T103M	probably damaging	Het
Ubap2l	A	C	3: 89,922,713 (GRCm39)	V775G	unknown	Het
Vmn2r69	A	C	7: 85,060,972 (GRCm39)	I204R	possibly damaging	Het
Vmn2r72	T	A	7: 85,399,771 (GRCm39)	D426V	probably benign	Het
Vmn2r93	G	A	17: 18,533,497 (GRCm39)	W467*	probably null	Het
Wbp2nl	T	C	15: 82,198,542 (GRCm39)	*360Q	probably null	Het
Xylt1	G	A	7: 117,191,274 (GRCm39)		probably null	Het
Zc3h6	T	G	2: 128,835,331 (GRCm39)	N123K	unknown	Het
Zfp853	T	C	5: 143,275,110 (GRCm39)	Q185R	unknown	Het

Other mutations in Dnah1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00090:Dnah1	APN	14	31,009,830 (GRCm39)	missense	probably benign	0.01
IGL00227:Dnah1	APN	14	31,008,853 (GRCm39)	missense	probably damaging	1.00
IGL00491:Dnah1	APN	14	30,983,796 (GRCm39)	missense	probably damaging	1.00
IGL00787:Dnah1	APN	14	31,022,020 (GRCm39)	missense	possibly damaging	0.91
IGL00809:Dnah1	APN	14	31,022,766 (GRCm39)	nonsense	probably null
IGL00911:Dnah1	APN	14	31,026,391 (GRCm39)	splice site	probably null
IGL00949:Dnah1	APN	14	31,029,047 (GRCm39)	missense	probably benign	0.00
IGL00976:Dnah1	APN	14	31,000,095 (GRCm39)	missense	probably damaging	1.00
IGL01484:Dnah1	APN	14	31,021,897 (GRCm39)	missense	probably damaging	0.98
IGL01629:Dnah1	APN	14	31,014,277 (GRCm39)	missense	probably damaging	1.00
IGL01716:Dnah1	APN	14	30,985,335 (GRCm39)	missense	probably benign	0.34
IGL01893:Dnah1	APN	14	30,988,427 (GRCm39)	missense	probably damaging	1.00
IGL01933:Dnah1	APN	14	31,032,872 (GRCm39)	missense	probably benign	0.40
IGL01938:Dnah1	APN	14	31,005,844 (GRCm39)	missense	probably benign
IGL02032:Dnah1	APN	14	30,996,326 (GRCm39)	missense	probably benign
IGL02052:Dnah1	APN	14	30,990,743 (GRCm39)	missense	probably damaging	0.99
IGL02097:Dnah1	APN	14	31,026,958 (GRCm39)	missense	possibly damaging	0.92
IGL02127:Dnah1	APN	14	31,026,885 (GRCm39)	missense	probably benign	0.00
IGL02143:Dnah1	APN	14	31,005,246 (GRCm39)	missense	probably damaging	1.00
IGL02158:Dnah1	APN	14	31,022,924 (GRCm39)	missense	probably benign	0.00
IGL02442:Dnah1	APN	14	31,009,835 (GRCm39)	missense	probably damaging	1.00
IGL02525:Dnah1	APN	14	31,027,790 (GRCm39)	missense	probably benign	0.05
IGL02558:Dnah1	APN	14	30,996,336 (GRCm39)	missense	possibly damaging	0.96
IGL02633:Dnah1	APN	14	31,006,772 (GRCm39)	missense	probably benign	0.05
IGL02720:Dnah1	APN	14	30,984,177 (GRCm39)	missense	probably damaging	0.96
IGL02728:Dnah1	APN	14	31,005,955 (GRCm39)	missense	probably benign	0.44
IGL02738:Dnah1	APN	14	31,014,597 (GRCm39)	missense	probably benign	0.27
IGL02863:Dnah1	APN	14	31,017,250 (GRCm39)	missense	probably damaging	0.99
IGL02944:Dnah1	APN	14	31,022,828 (GRCm39)	missense	possibly damaging	0.88
IGL03110:Dnah1	APN	14	30,988,674 (GRCm39)	missense	probably benign	0.40
IGL03201:Dnah1	APN	14	31,022,906 (GRCm39)	missense	probably benign	0.13
IGL03215:Dnah1	APN	14	30,996,348 (GRCm39)	missense	probably damaging	1.00
IGL03230:Dnah1	APN	14	30,992,023 (GRCm39)	missense	probably damaging	1.00
IGL03248:Dnah1	APN	14	30,991,846 (GRCm39)	missense	probably damaging	1.00
IGL03267:Dnah1	APN	14	31,008,545 (GRCm39)	missense	probably benign	0.00
IGL03299:Dnah1	APN	14	31,037,079 (GRCm39)	nonsense	probably null
IGL03301:Dnah1	APN	14	31,014,649 (GRCm39)	missense	probably damaging	1.00
ergonomic	UTSW	14	31,022,705 (GRCm39)	missense	possibly damaging	0.91
Faraday	UTSW	14	31,032,839 (GRCm39)	missense	probably null	0.05
K3955:Dnah1	UTSW	14	30,988,416 (GRCm39)	missense	probably benign
PIT1430001:Dnah1	UTSW	14	30,984,537 (GRCm39)	missense	probably damaging	1.00
PIT4382001:Dnah1	UTSW	14	31,006,412 (GRCm39)	missense	probably damaging	1.00
R0043:Dnah1	UTSW	14	30,996,362 (GRCm39)	missense	probably damaging	0.97
R0092:Dnah1	UTSW	14	30,993,566 (GRCm39)	missense	probably benign	0.00
R0100:Dnah1	UTSW	14	30,984,109 (GRCm39)	critical splice donor site	probably null
R0100:Dnah1	UTSW	14	30,984,109 (GRCm39)	critical splice donor site	probably null
R0101:Dnah1	UTSW	14	31,005,856 (GRCm39)	missense	probably damaging	1.00
R0119:Dnah1	UTSW	14	30,998,115 (GRCm39)	missense	probably damaging	1.00
R0136:Dnah1	UTSW	14	30,998,115 (GRCm39)	missense	probably damaging	1.00
R0144:Dnah1	UTSW	14	30,989,831 (GRCm39)	splice site	probably benign
R0279:Dnah1	UTSW	14	31,024,332 (GRCm39)	missense	possibly damaging	0.94
R0299:Dnah1	UTSW	14	30,998,115 (GRCm39)	missense	probably damaging	1.00
R0316:Dnah1	UTSW	14	31,000,108 (GRCm39)	missense	probably benign	0.00
R0739:Dnah1	UTSW	14	30,987,872 (GRCm39)	nonsense	probably null
R0789:Dnah1	UTSW	14	31,026,548 (GRCm39)	missense	probably benign
R0826:Dnah1	UTSW	14	31,025,864 (GRCm39)	missense	probably benign	0.02
R1102:Dnah1	UTSW	14	31,018,414 (GRCm39)	nonsense	probably null
R1116:Dnah1	UTSW	14	31,029,824 (GRCm39)	missense	probably benign	0.13
R1229:Dnah1	UTSW	14	31,032,808 (GRCm39)	missense	probably benign	0.11
R1447:Dnah1	UTSW	14	31,028,855 (GRCm39)	missense	probably benign	0.06
R1449:Dnah1	UTSW	14	30,985,908 (GRCm39)	missense	probably damaging	1.00
R1462:Dnah1	UTSW	14	30,990,738 (GRCm39)	splice site	probably benign
R1482:Dnah1	UTSW	14	31,016,831 (GRCm39)	missense	probably damaging	1.00
R1500:Dnah1	UTSW	14	31,038,715 (GRCm39)	missense	probably benign
R1512:Dnah1	UTSW	14	31,014,994 (GRCm39)	missense	probably damaging	1.00
R1591:Dnah1	UTSW	14	30,994,289 (GRCm39)	missense	probably benign	0.01
R1598:Dnah1	UTSW	14	31,023,219 (GRCm39)	missense	probably benign	0.07
R1644:Dnah1	UTSW	14	31,024,249 (GRCm39)	splice site	probably benign
R1672:Dnah1	UTSW	14	30,998,157 (GRCm39)	missense	probably damaging	1.00
R1713:Dnah1	UTSW	14	31,001,139 (GRCm39)	missense	probably damaging	1.00
R1769:Dnah1	UTSW	14	31,032,839 (GRCm39)	missense	probably null	0.05
R1796:Dnah1	UTSW	14	30,983,050 (GRCm39)	missense	probably benign	0.00
R1902:Dnah1	UTSW	14	31,041,716 (GRCm39)	missense	probably damaging	0.99
R1903:Dnah1	UTSW	14	31,041,716 (GRCm39)	missense	probably damaging	0.99
R1905:Dnah1	UTSW	14	30,986,587 (GRCm39)	missense	probably benign	0.06
R1908:Dnah1	UTSW	14	30,984,515 (GRCm39)	missense	probably damaging	1.00
R1972:Dnah1	UTSW	14	30,987,348 (GRCm39)	nonsense	probably null
R1973:Dnah1	UTSW	14	30,987,348 (GRCm39)	nonsense	probably null
R2004:Dnah1	UTSW	14	31,023,813 (GRCm39)	missense	possibly damaging	0.79
R2051:Dnah1	UTSW	14	31,001,080 (GRCm39)	missense	probably damaging	1.00
R2062:Dnah1	UTSW	14	30,993,086 (GRCm39)	missense	probably damaging	1.00
R2188:Dnah1	UTSW	14	31,001,121 (GRCm39)	missense	probably damaging	0.98
R2240:Dnah1	UTSW	14	31,021,931 (GRCm39)	missense	probably benign	0.00
R2862:Dnah1	UTSW	14	31,006,719 (GRCm39)	missense	probably benign	0.21
R2894:Dnah1	UTSW	14	31,020,718 (GRCm39)	missense	possibly damaging	0.67
R3120:Dnah1	UTSW	14	30,988,779 (GRCm39)	nonsense	probably null
R3410:Dnah1	UTSW	14	30,991,774 (GRCm39)	missense	possibly damaging	0.55
R3411:Dnah1	UTSW	14	30,991,774 (GRCm39)	missense	possibly damaging	0.55
R3435:Dnah1	UTSW	14	31,038,631 (GRCm39)	missense	probably damaging	0.96
R3615:Dnah1	UTSW	14	31,037,105 (GRCm39)	missense	possibly damaging	0.92
R3616:Dnah1	UTSW	14	31,037,105 (GRCm39)	missense	possibly damaging	0.92
R3741:Dnah1	UTSW	14	30,987,424 (GRCm39)	splice site	probably benign
R3805:Dnah1	UTSW	14	31,016,720 (GRCm39)	missense	possibly damaging	0.67
R3894:Dnah1	UTSW	14	31,028,985 (GRCm39)	missense	probably benign
R4007:Dnah1	UTSW	14	31,025,741 (GRCm39)	splice site	probably benign
R4201:Dnah1	UTSW	14	30,984,227 (GRCm39)	missense	probably benign	0.00
R4232:Dnah1	UTSW	14	31,026,873 (GRCm39)	missense	probably benign
R4372:Dnah1	UTSW	14	31,026,879 (GRCm39)	missense	probably damaging	1.00
R4391:Dnah1	UTSW	14	31,016,792 (GRCm39)	missense	probably damaging	1.00
R4423:Dnah1	UTSW	14	31,006,718 (GRCm39)	missense	probably benign	0.00
R4526:Dnah1	UTSW	14	31,007,955 (GRCm39)	missense	probably benign	0.05
R4650:Dnah1	UTSW	14	31,006,844 (GRCm39)	splice site	probably null
R4723:Dnah1	UTSW	14	30,994,899 (GRCm39)	missense	probably damaging	1.00
R4748:Dnah1	UTSW	14	31,041,902 (GRCm39)	missense	probably benign
R4783:Dnah1	UTSW	14	30,985,436 (GRCm39)	missense	probably damaging	1.00
R4784:Dnah1	UTSW	14	30,985,436 (GRCm39)	missense	probably damaging	1.00
R4785:Dnah1	UTSW	14	30,985,436 (GRCm39)	missense	probably damaging	1.00
R4843:Dnah1	UTSW	14	30,986,920 (GRCm39)	missense	probably damaging	1.00
R4879:Dnah1	UTSW	14	31,022,705 (GRCm39)	missense	possibly damaging	0.91
R4897:Dnah1	UTSW	14	30,989,496 (GRCm39)	missense	probably damaging	1.00
R4911:Dnah1	UTSW	14	31,017,280 (GRCm39)	missense	probably damaging	1.00
R4985:Dnah1	UTSW	14	31,008,855 (GRCm39)	missense	probably null	1.00
R5070:Dnah1	UTSW	14	31,004,375 (GRCm39)	missense	probably benign	0.05
R5128:Dnah1	UTSW	14	31,018,152 (GRCm39)	splice site	probably null
R5409:Dnah1	UTSW	14	30,985,212 (GRCm39)	missense	probably damaging	1.00
R5436:Dnah1	UTSW	14	31,038,704 (GRCm39)	missense	probably benign
R5481:Dnah1	UTSW	14	31,030,828 (GRCm39)	missense	possibly damaging	0.55
R5550:Dnah1	UTSW	14	31,038,665 (GRCm39)	missense	probably benign	0.00
R5555:Dnah1	UTSW	14	31,012,776 (GRCm39)	missense	probably damaging	0.99
R5566:Dnah1	UTSW	14	30,996,323 (GRCm39)	missense	probably benign	0.35
R5623:Dnah1	UTSW	14	31,007,980 (GRCm39)	missense	possibly damaging	0.62
R5701:Dnah1	UTSW	14	30,996,001 (GRCm39)	missense	probably damaging	1.00
R5751:Dnah1	UTSW	14	31,032,863 (GRCm39)	missense	probably benign	0.00
R5823:Dnah1	UTSW	14	30,988,375 (GRCm39)	missense	possibly damaging	0.92
R6030:Dnah1	UTSW	14	30,989,984 (GRCm39)	missense	probably damaging	1.00
R6030:Dnah1	UTSW	14	30,989,984 (GRCm39)	missense	probably damaging	1.00
R6090:Dnah1	UTSW	14	30,991,382 (GRCm39)	missense	possibly damaging	0.83
R6139:Dnah1	UTSW	14	31,007,984 (GRCm39)	missense	probably benign	0.02
R6145:Dnah1	UTSW	14	31,022,927 (GRCm39)	missense	probably benign	0.07
R6306:Dnah1	UTSW	14	31,026,544 (GRCm39)	missense	probably damaging	0.97
R6376:Dnah1	UTSW	14	30,997,565 (GRCm39)	missense	probably damaging	1.00
R6451:Dnah1	UTSW	14	31,022,765 (GRCm39)	missense	probably benign	0.08
R6549:Dnah1	UTSW	14	30,991,340 (GRCm39)	missense	probably damaging	1.00
R6748:Dnah1	UTSW	14	31,021,945 (GRCm39)	missense	probably damaging	0.99
R6826:Dnah1	UTSW	14	31,008,247 (GRCm39)	missense	probably benign	0.00
R6870:Dnah1	UTSW	14	30,993,018 (GRCm39)	nonsense	probably null
R6932:Dnah1	UTSW	14	31,009,733 (GRCm39)	missense	probably damaging	1.00
R6944:Dnah1	UTSW	14	30,990,861 (GRCm39)	missense	probably damaging	1.00
R7033:Dnah1	UTSW	14	30,986,882 (GRCm39)	missense	probably damaging	1.00
R7078:Dnah1	UTSW	14	31,019,067 (GRCm39)	missense	probably damaging	1.00
R7133:Dnah1	UTSW	14	31,008,033 (GRCm39)	missense	probably benign
R7136:Dnah1	UTSW	14	31,020,613 (GRCm39)	missense	probably damaging	1.00
R7203:Dnah1	UTSW	14	30,996,339 (GRCm39)	missense	probably benign
R7241:Dnah1	UTSW	14	30,986,896 (GRCm39)	missense	probably benign	0.00
R7260:Dnah1	UTSW	14	30,991,343 (GRCm39)	missense	probably damaging	1.00
R7264:Dnah1	UTSW	14	30,991,851 (GRCm39)	missense	probably benign
R7291:Dnah1	UTSW	14	31,020,662 (GRCm39)	missense	probably damaging	1.00
R7293:Dnah1	UTSW	14	31,009,820 (GRCm39)	missense	probably damaging	1.00
R7300:Dnah1	UTSW	14	30,991,798 (GRCm39)	missense	probably benign	0.05
R7319:Dnah1	UTSW	14	31,018,551 (GRCm39)	missense	probably benign	0.02
R7472:Dnah1	UTSW	14	31,022,748 (GRCm39)	missense	possibly damaging	0.80
R7472:Dnah1	UTSW	14	30,983,547 (GRCm39)	missense	probably damaging	1.00
R7499:Dnah1	UTSW	14	31,037,079 (GRCm39)	nonsense	probably null
R7526:Dnah1	UTSW	14	31,009,833 (GRCm39)	missense	possibly damaging	0.49
R7560:Dnah1	UTSW	14	31,026,940 (GRCm39)	missense	probably benign
R7574:Dnah1	UTSW	14	31,041,865 (GRCm39)	missense	probably benign	0.00
R7617:Dnah1	UTSW	14	31,006,739 (GRCm39)	missense	possibly damaging	0.80
R7620:Dnah1	UTSW	14	31,025,863 (GRCm39)	missense	possibly damaging	0.47
R7692:Dnah1	UTSW	14	31,014,295 (GRCm39)	missense	probably benign	0.00
R7702:Dnah1	UTSW	14	31,032,866 (GRCm39)	missense	probably benign
R7786:Dnah1	UTSW	14	30,984,478 (GRCm39)	missense	probably damaging	1.00
R7984:Dnah1	UTSW	14	30,989,772 (GRCm39)	missense	probably damaging	1.00
R8002:Dnah1	UTSW	14	31,020,679 (GRCm39)	missense	probably damaging	1.00
R8022:Dnah1	UTSW	14	30,986,971 (GRCm39)	missense	probably damaging	1.00
R8032:Dnah1	UTSW	14	30,993,505 (GRCm39)	missense	probably damaging	1.00
R8099:Dnah1	UTSW	14	31,024,321 (GRCm39)	missense	probably benign	0.00
R8171:Dnah1	UTSW	14	31,019,067 (GRCm39)	missense	probably damaging	1.00
R8263:Dnah1	UTSW	14	31,015,134 (GRCm39)	missense	probably damaging	1.00
R8274:Dnah1	UTSW	14	31,017,531 (GRCm39)	missense	probably benign	0.00
R8345:Dnah1	UTSW	14	30,986,551 (GRCm39)	missense	probably damaging	1.00
R8348:Dnah1	UTSW	14	31,015,682 (GRCm39)	missense	probably damaging	1.00
R8353:Dnah1	UTSW	14	31,005,159 (GRCm39)	missense	probably benign
R8356:Dnah1	UTSW	14	30,994,972 (GRCm39)	missense	probably benign	0.00
R8376:Dnah1	UTSW	14	31,023,303 (GRCm39)	missense	probably damaging	1.00
R8448:Dnah1	UTSW	14	31,015,682 (GRCm39)	missense	probably damaging	1.00
R8461:Dnah1	UTSW	14	31,027,915 (GRCm39)	missense	probably benign	0.00
R8534:Dnah1	UTSW	14	31,023,805 (GRCm39)	missense	probably benign	0.16
R8544:Dnah1	UTSW	14	30,990,861 (GRCm39)	missense	probably damaging	1.00
R8679:Dnah1	UTSW	14	30,989,767 (GRCm39)	missense	possibly damaging	0.77
R8716:Dnah1	UTSW	14	30,989,941 (GRCm39)	critical splice donor site	probably benign
R8750:Dnah1	UTSW	14	31,026,924 (GRCm39)	missense	probably benign	0.30
R8790:Dnah1	UTSW	14	31,018,232 (GRCm39)	missense	possibly damaging	0.89
R8808:Dnah1	UTSW	14	31,008,771 (GRCm39)	missense	probably benign
R8821:Dnah1	UTSW	14	31,018,455 (GRCm39)	missense	probably benign
R8887:Dnah1	UTSW	14	31,032,997 (GRCm39)	missense	probably damaging	1.00
R8948:Dnah1	UTSW	14	31,012,396 (GRCm39)	missense	probably damaging	1.00
R8950:Dnah1	UTSW	14	31,012,396 (GRCm39)	missense	probably damaging	1.00
R8955:Dnah1	UTSW	14	31,007,950 (GRCm39)	missense	probably benign
R8987:Dnah1	UTSW	14	31,033,704 (GRCm39)	missense	possibly damaging	0.93
R8998:Dnah1	UTSW	14	31,018,235 (GRCm39)	missense	probably benign	0.12
R8999:Dnah1	UTSW	14	31,018,235 (GRCm39)	missense	probably benign	0.12
R9015:Dnah1	UTSW	14	30,986,316 (GRCm39)	missense	probably damaging	0.96
R9031:Dnah1	UTSW	14	31,001,128 (GRCm39)	missense	probably benign
R9088:Dnah1	UTSW	14	30,987,970 (GRCm39)	missense	probably benign	0.04
R9096:Dnah1	UTSW	14	30,983,027 (GRCm39)	missense	probably damaging	0.99
R9117:Dnah1	UTSW	14	31,033,581 (GRCm39)	splice site	probably benign
R9157:Dnah1	UTSW	14	30,987,970 (GRCm39)	missense	probably damaging	0.97
R9296:Dnah1	UTSW	14	30,996,011 (GRCm39)	critical splice acceptor site	probably null
R9313:Dnah1	UTSW	14	30,987,970 (GRCm39)	missense	probably damaging	0.97
R9325:Dnah1	UTSW	14	30,998,160 (GRCm39)	missense	possibly damaging	0.69
R9352:Dnah1	UTSW	14	31,038,620 (GRCm39)	missense	probably benign	0.00
R9411:Dnah1	UTSW	14	31,018,256 (GRCm39)	missense	probably damaging	1.00
R9429:Dnah1	UTSW	14	30,997,499 (GRCm39)	nonsense	probably null
R9452:Dnah1	UTSW	14	31,018,448 (GRCm39)	missense	probably benign	0.35
R9562:Dnah1	UTSW	14	30,986,394 (GRCm39)	missense	probably damaging	1.00
R9565:Dnah1	UTSW	14	30,986,394 (GRCm39)	missense	probably damaging	1.00
R9616:Dnah1	UTSW	14	31,026,400 (GRCm39)	missense	probably null	0.20
R9621:Dnah1	UTSW	14	31,016,772 (GRCm39)	missense	probably damaging	1.00
R9677:Dnah1	UTSW	14	31,029,821 (GRCm39)	missense	probably benign	0.00
R9723:Dnah1	UTSW	14	30,987,946 (GRCm39)	missense	probably damaging	1.00
R9758:Dnah1	UTSW	14	30,985,395 (GRCm39)	missense	probably damaging	0.98
RF006:Dnah1	UTSW	14	31,029,832 (GRCm39)	missense	probably benign	0.08
Z1088:Dnah1	UTSW	14	31,026,768 (GRCm39)	missense	probably benign	0.17

Predicted Primers

PCR Primer
(F):5'- CCAGCAATGTGATCAGGACC -3'
(R):5'- AAGCCCCAAGTGCAGAATTGG -3'

Sequencing Primer
(F):5'- CAATGTGATCAGGACCTTGGG -3'
(R):5'- CGCTACCTAGTAGATGCTGATGC -3'

Posted On

2019-06-26