Incidental Mutation 'R7324:Mmrn1'
| ID |
568738 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mmrn1
|
| Ensembl Gene |
ENSMUSG00000054641 |
| Gene Name |
multimerin 1 |
| Synonyms |
Emilin4, 4921530G03Rik |
| MMRRC Submission |
045418-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7324 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
60921301-60966362 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
G to T
at 60921917 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Stop codon
at position 125
(G125*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000119609
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000129603]
[ENSMUST00000204333]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably null
Transcript: ENSMUST00000129603
AA Change: G125*
|
| SMART Domains |
Protein: ENSMUSP00000119609
Gene: ENSMUSG00000054641
AA Change: G125*
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
80 |
92 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
193 |
262 |
3.3e-12 |
PFAM |
|
coiled coil region
|
303 |
338 |
N/A |
INTRINSIC |
|
coiled coil region
|
658 |
688 |
N/A |
INTRINSIC |
|
coiled coil region
|
808 |
846 |
N/A |
INTRINSIC |
|
low complexity region
|
981 |
992 |
N/A |
INTRINSIC |
|
EGF
|
1026 |
1059 |
1.62e-5 |
SMART |
|
C1Q
|
1076 |
1210 |
6.74e-49 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000204333
AA Change: G125*
|
| SMART Domains |
Protein: ENSMUSP00000145156
Gene: ENSMUSG00000054641
AA Change: G125*
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
80 |
92 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
193 |
262 |
7.7e-13 |
PFAM |
|
coiled coil region
|
303 |
338 |
N/A |
INTRINSIC |
|
coiled coil region
|
658 |
688 |
N/A |
INTRINSIC |
|
coiled coil region
|
808 |
846 |
N/A |
INTRINSIC |
|
low complexity region
|
981 |
992 |
N/A |
INTRINSIC |
|
EGF
|
1025 |
1058 |
1.62e-5 |
SMART |
|
C1Q
|
1075 |
1209 |
6.74e-49 |
SMART |
|
| Meta Mutation Damage Score |
0.9406 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
99% (81/82) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcg5 |
T |
C |
17: 84,983,667 (GRCm39) |
D124G |
possibly damaging |
Het |
| Ackr3 |
C |
G |
1: 90,141,923 (GRCm39) |
N127K |
probably damaging |
Het |
| AL732309.1 |
A |
C |
2: 25,136,151 (GRCm39) |
M21R |
possibly damaging |
Het |
| Ankrd52 |
C |
A |
10: 128,222,032 (GRCm39) |
T552K |
possibly damaging |
Het |
| Arhgap28 |
T |
C |
17: 68,202,879 (GRCm39) |
|
probably null |
Het |
| Arid5b |
A |
T |
10: 67,964,752 (GRCm39) |
N306K |
probably benign |
Het |
| C1qtnf3 |
A |
C |
15: 10,952,707 (GRCm39) |
K56N |
probably benign |
Het |
| C2 |
C |
T |
17: 35,100,664 (GRCm39) |
G52D |
probably benign |
Het |
| Casz1 |
C |
T |
4: 149,031,490 (GRCm39) |
T1247M |
probably damaging |
Het |
| Cc2d2b |
A |
G |
19: 40,797,552 (GRCm39) |
D778G |
unknown |
Het |
| Cdh5 |
A |
G |
8: 104,869,425 (GRCm39) |
D717G |
probably damaging |
Het |
| Clca3a2 |
G |
A |
3: 144,514,372 (GRCm39) |
A445V |
probably damaging |
Het |
| Clca3b |
T |
A |
3: 144,547,181 (GRCm39) |
M319L |
possibly damaging |
Het |
| Csmd1 |
G |
A |
8: 16,108,721 (GRCm39) |
S1894L |
probably damaging |
Het |
| Csnk1g3 |
A |
G |
18: 54,052,090 (GRCm39) |
T220A |
probably damaging |
Het |
| Cyp2d10 |
T |
G |
15: 82,287,961 (GRCm39) |
T381P |
probably damaging |
Het |
| Ddb2 |
G |
A |
2: 91,067,229 (GRCm39) |
|
probably benign |
Het |
| Ddx24 |
C |
A |
12: 103,382,518 (GRCm39) |
L688F |
probably damaging |
Het |
| Dennd4c |
T |
C |
4: 86,747,975 (GRCm39) |
L1615P |
unknown |
Het |
| Dnah8 |
T |
A |
17: 31,003,099 (GRCm39) |
D3599E |
probably benign |
Het |
| Dst |
T |
C |
1: 34,045,305 (GRCm39) |
S13P |
possibly damaging |
Het |
| Efcab12 |
T |
C |
6: 115,800,555 (GRCm39) |
D156G |
probably benign |
Het |
| Enpp2 |
A |
G |
15: 54,741,170 (GRCm39) |
|
probably null |
Het |
| Ephx2 |
A |
G |
14: 66,322,803 (GRCm39) |
V490A |
probably damaging |
Het |
| Etnppl |
A |
G |
3: 130,423,224 (GRCm39) |
N308D |
probably damaging |
Het |
| F5 |
TCAGAAGACCTCCTCCCCAGACCTGGGCCAGGTGCCCCTTTCTCCAGATGACAACCAGAAGACCTCCTCCCCAGACCTGGGTCAGGTGTCCCTTTCTCCAGATGATAACCAGAAGACCTCCTCCCCAGACCTGGGTCAGGTGCCCCTTTCTCTAGATGACAACCAGAAGACGACCTCCCCAGACCTGGGTCAGGTGCCCCTTTCTCCAGATGACAACCAGA |
TCAGAAGACCTCCTCCCCAGACCTGGGTCAGGTGTCCCTTTCTCCAGATGATAACCAGAAGACCTCCTCCCCAGACCTGGGTCAGGTGCCCCTTTCTCTAGATGACAACCAGAAGACGACCTCCCCAGACCTGGGTCAGGTGCCCCTTTCTCCAGATGACAACCAGA |
1: 164,021,150 (GRCm39) |
|
probably benign |
Het |
| Fam162b |
A |
T |
10: 51,466,282 (GRCm39) |
|
probably null |
Het |
| Fancl |
A |
G |
11: 26,353,362 (GRCm39) |
E86G |
probably damaging |
Het |
| Flii |
G |
A |
11: 60,609,866 (GRCm39) |
T615I |
probably benign |
Het |
| Fndc7 |
G |
T |
3: 108,779,537 (GRCm39) |
Q336K |
probably benign |
Het |
| Gm26661 |
T |
C |
14: 7,791,911 (GRCm38) |
C109R |
unknown |
Het |
| H2-DMb1 |
T |
C |
17: 34,378,436 (GRCm39) |
|
probably null |
Het |
| H2-T10 |
C |
T |
17: 36,430,189 (GRCm39) |
G251R |
probably damaging |
Het |
| Harbi1 |
T |
C |
2: 91,551,044 (GRCm39) |
I339T |
probably benign |
Het |
| Hsp90aa1 |
A |
G |
12: 110,661,659 (GRCm39) |
M119T |
unknown |
Het |
| Ighe |
T |
A |
12: 113,235,954 (GRCm39) |
Y124F |
|
Het |
| Ighv7-1 |
T |
C |
12: 113,860,149 (GRCm39) |
Y81C |
probably damaging |
Het |
| Ilkap |
A |
T |
1: 91,313,115 (GRCm39) |
|
probably null |
Het |
| Inpp5a |
A |
G |
7: 139,105,586 (GRCm39) |
D179G |
probably damaging |
Het |
| Itgad |
A |
T |
7: 127,788,979 (GRCm39) |
D510V |
probably damaging |
Het |
| Kcnn2 |
A |
T |
18: 45,693,138 (GRCm39) |
H238L |
probably benign |
Het |
| Kctd17 |
T |
A |
15: 78,319,842 (GRCm39) |
C189S |
probably damaging |
Het |
| Larp4b |
C |
A |
13: 9,208,616 (GRCm39) |
A423E |
probably benign |
Het |
| Llgl2 |
A |
G |
11: 115,741,556 (GRCm39) |
E562G |
possibly damaging |
Het |
| Macf1 |
T |
C |
4: 123,268,218 (GRCm39) |
T6734A |
probably benign |
Het |
| Maz |
G |
A |
7: 126,623,765 (GRCm39) |
T377M |
probably damaging |
Het |
| Mvp |
A |
G |
7: 126,592,781 (GRCm39) |
S377P |
probably benign |
Het |
| Nin |
C |
T |
12: 70,090,508 (GRCm39) |
R969Q |
|
Het |
| Nktr |
C |
T |
9: 121,556,427 (GRCm39) |
T35I |
probably damaging |
Het |
| Nktr |
T |
A |
9: 121,577,357 (GRCm39) |
M475K |
possibly damaging |
Het |
| Nod2 |
T |
A |
8: 89,379,694 (GRCm39) |
V65D |
probably damaging |
Het |
| Opa1 |
A |
T |
16: 29,405,799 (GRCm39) |
E121D |
probably benign |
Het |
| Or10w3 |
C |
T |
19: 13,704,270 (GRCm39) |
A215V |
probably benign |
Het |
| Or1r1 |
A |
G |
11: 73,874,669 (GRCm39) |
V255A |
probably benign |
Het |
| Or2n1c |
T |
C |
17: 38,519,607 (GRCm39) |
V157A |
probably benign |
Het |
| Or4a76 |
A |
T |
2: 89,460,447 (GRCm39) |
I265N |
possibly damaging |
Het |
| Or5ac21 |
T |
C |
16: 59,123,611 (GRCm39) |
F32L |
probably benign |
Het |
| Or5b123 |
A |
G |
19: 13,596,942 (GRCm39) |
I96V |
probably benign |
Het |
| Or6c88 |
T |
A |
10: 129,406,718 (GRCm39) |
S65T |
probably damaging |
Het |
| Or7e174 |
A |
T |
9: 20,012,726 (GRCm39) |
I224F |
possibly damaging |
Het |
| Osbpl2 |
A |
G |
2: 179,791,994 (GRCm39) |
T233A |
probably benign |
Het |
| Pcp4l1 |
G |
A |
1: 171,002,034 (GRCm39) |
A42V |
possibly damaging |
Het |
| Plekhh3 |
T |
A |
11: 101,061,600 (GRCm39) |
D38V |
possibly damaging |
Het |
| Prtg |
C |
T |
9: 72,798,122 (GRCm39) |
A696V |
probably damaging |
Het |
| Ptpn14 |
T |
G |
1: 189,595,621 (GRCm39) |
V748G |
possibly damaging |
Het |
| Reg2 |
A |
T |
6: 78,383,137 (GRCm39) |
D28V |
probably benign |
Het |
| Rhpn1 |
A |
T |
15: 75,576,246 (GRCm39) |
I2F |
possibly damaging |
Het |
| Rundc3a |
A |
G |
11: 102,290,799 (GRCm39) |
E294G |
possibly damaging |
Het |
| Scara3 |
T |
A |
14: 66,168,865 (GRCm39) |
I251L |
probably benign |
Het |
| Slc23a2 |
G |
A |
2: 131,931,043 (GRCm39) |
T152I |
probably damaging |
Het |
| Slc39a2 |
T |
G |
14: 52,131,650 (GRCm39) |
S74A |
possibly damaging |
Het |
| Tmprss15 |
T |
C |
16: 78,758,907 (GRCm39) |
Y937C |
probably damaging |
Het |
| Tpp2 |
T |
C |
1: 44,017,938 (GRCm39) |
L779S |
probably damaging |
Het |
| Tssk2 |
T |
C |
16: 17,717,227 (GRCm39) |
V210A |
possibly damaging |
Het |
| Ttn |
T |
A |
2: 76,725,937 (GRCm39) |
T6100S |
unknown |
Het |
| Tufm |
G |
A |
7: 126,088,759 (GRCm39) |
E317K |
possibly damaging |
Het |
| Vinac1 |
T |
C |
2: 128,879,772 (GRCm39) |
D718G |
unknown |
Het |
| Wdfy4 |
A |
G |
14: 32,769,271 (GRCm39) |
S2219P |
|
Het |
| Wtap |
T |
C |
17: 13,199,833 (GRCm39) |
N50S |
possibly damaging |
Het |
|
| Other mutations in Mmrn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00640:Mmrn1
|
APN |
6 |
60,954,497 (GRCm39) |
missense |
probably benign |
|
|
IGL00742:Mmrn1
|
APN |
6 |
60,935,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00917:Mmrn1
|
APN |
6 |
60,952,894 (GRCm39) |
nonsense |
probably null |
|
|
IGL01121:Mmrn1
|
APN |
6 |
60,952,928 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL01393:Mmrn1
|
APN |
6 |
60,937,692 (GRCm39) |
splice site |
probably benign |
|
|
IGL01697:Mmrn1
|
APN |
6 |
60,953,477 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL01737:Mmrn1
|
APN |
6 |
60,954,145 (GRCm39) |
missense |
probably benign |
|
|
IGL01944:Mmrn1
|
APN |
6 |
60,948,167 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01987:Mmrn1
|
APN |
6 |
60,921,557 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02005:Mmrn1
|
APN |
6 |
60,937,728 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02190:Mmrn1
|
APN |
6 |
60,964,177 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02335:Mmrn1
|
APN |
6 |
60,954,131 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL02421:Mmrn1
|
APN |
6 |
60,921,806 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02530:Mmrn1
|
APN |
6 |
60,935,160 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL02709:Mmrn1
|
APN |
6 |
60,950,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03139:Mmrn1
|
APN |
6 |
60,953,324 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03228:Mmrn1
|
APN |
6 |
60,921,876 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03272:Mmrn1
|
APN |
6 |
60,965,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03410:Mmrn1
|
APN |
6 |
60,952,819 (GRCm39) |
missense |
probably benign |
0.36 |
|
H8562:Mmrn1
|
UTSW |
6 |
60,935,164 (GRCm39) |
missense |
probably damaging |
0.98 |
|
K2124:Mmrn1
|
UTSW |
6 |
60,953,017 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0145:Mmrn1
|
UTSW |
6 |
60,949,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0164:Mmrn1
|
UTSW |
6 |
60,952,799 (GRCm39) |
splice site |
probably benign |
|
|
R0352:Mmrn1
|
UTSW |
6 |
60,921,955 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0400:Mmrn1
|
UTSW |
6 |
60,954,099 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0538:Mmrn1
|
UTSW |
6 |
60,953,453 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0907:Mmrn1
|
UTSW |
6 |
60,950,103 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1117:Mmrn1
|
UTSW |
6 |
60,953,309 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1383:Mmrn1
|
UTSW |
6 |
60,953,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1542:Mmrn1
|
UTSW |
6 |
60,922,102 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1591:Mmrn1
|
UTSW |
6 |
60,921,755 (GRCm39) |
nonsense |
probably null |
|
|
R1599:Mmrn1
|
UTSW |
6 |
60,922,021 (GRCm39) |
missense |
probably benign |
|
|
R1733:Mmrn1
|
UTSW |
6 |
60,954,085 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2005:Mmrn1
|
UTSW |
6 |
60,953,068 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2056:Mmrn1
|
UTSW |
6 |
60,921,789 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2144:Mmrn1
|
UTSW |
6 |
60,922,059 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R2299:Mmrn1
|
UTSW |
6 |
60,953,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3836:Mmrn1
|
UTSW |
6 |
60,921,831 (GRCm39) |
missense |
probably benign |
|
|
R3837:Mmrn1
|
UTSW |
6 |
60,921,831 (GRCm39) |
missense |
probably benign |
|
|
R4206:Mmrn1
|
UTSW |
6 |
60,935,164 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4414:Mmrn1
|
UTSW |
6 |
60,921,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4590:Mmrn1
|
UTSW |
6 |
60,937,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4707:Mmrn1
|
UTSW |
6 |
60,965,457 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4820:Mmrn1
|
UTSW |
6 |
60,950,027 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4880:Mmrn1
|
UTSW |
6 |
60,953,423 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5166:Mmrn1
|
UTSW |
6 |
60,953,474 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5324:Mmrn1
|
UTSW |
6 |
60,953,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5887:Mmrn1
|
UTSW |
6 |
60,964,058 (GRCm39) |
missense |
probably benign |
|
|
R5917:Mmrn1
|
UTSW |
6 |
60,950,134 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6108:Mmrn1
|
UTSW |
6 |
60,952,960 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6539:Mmrn1
|
UTSW |
6 |
60,964,168 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6996:Mmrn1
|
UTSW |
6 |
60,954,367 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7064:Mmrn1
|
UTSW |
6 |
60,965,524 (GRCm39) |
nonsense |
probably null |
|
|
R7073:Mmrn1
|
UTSW |
6 |
60,965,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7213:Mmrn1
|
UTSW |
6 |
60,921,527 (GRCm39) |
start gained |
probably benign |
|
|
R7256:Mmrn1
|
UTSW |
6 |
60,953,098 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7350:Mmrn1
|
UTSW |
6 |
60,953,320 (GRCm39) |
nonsense |
probably null |
|
|
R7388:Mmrn1
|
UTSW |
6 |
60,953,236 (GRCm39) |
missense |
probably benign |
0.43 |
|
R7652:Mmrn1
|
UTSW |
6 |
60,954,490 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7664:Mmrn1
|
UTSW |
6 |
60,953,689 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7810:Mmrn1
|
UTSW |
6 |
60,953,309 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7832:Mmrn1
|
UTSW |
6 |
60,964,044 (GRCm39) |
splice site |
probably null |
|
|
R7979:Mmrn1
|
UTSW |
6 |
60,952,961 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8071:Mmrn1
|
UTSW |
6 |
60,921,508 (GRCm39) |
start gained |
probably benign |
|
|
R8130:Mmrn1
|
UTSW |
6 |
60,937,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8277:Mmrn1
|
UTSW |
6 |
60,954,220 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8353:Mmrn1
|
UTSW |
6 |
60,965,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8453:Mmrn1
|
UTSW |
6 |
60,965,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8472:Mmrn1
|
UTSW |
6 |
60,965,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8758:Mmrn1
|
UTSW |
6 |
60,964,193 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R8803:Mmrn1
|
UTSW |
6 |
60,965,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8879:Mmrn1
|
UTSW |
6 |
60,953,513 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8907:Mmrn1
|
UTSW |
6 |
60,953,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8983:Mmrn1
|
UTSW |
6 |
60,953,042 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9200:Mmrn1
|
UTSW |
6 |
60,953,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9287:Mmrn1
|
UTSW |
6 |
60,952,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9387:Mmrn1
|
UTSW |
6 |
60,935,176 (GRCm39) |
nonsense |
probably null |
|
|
R9612:Mmrn1
|
UTSW |
6 |
60,953,408 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9674:Mmrn1
|
UTSW |
6 |
60,948,072 (GRCm39) |
nonsense |
probably null |
|
|
X0026:Mmrn1
|
UTSW |
6 |
60,952,997 (GRCm39) |
missense |
probably benign |
0.09 |
|
Z1176:Mmrn1
|
UTSW |
6 |
60,922,018 (GRCm39) |
missense |
probably benign |
0.37 |
|
Z1177:Mmrn1
|
UTSW |
6 |
60,964,082 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
| Predicted Primers |
PCR Primer
(F):5'- AATACTGAGCCTCCAAGTGCTC -3'
(R):5'- CCCTCTAGTTGTTTCAAAACTGGG -3'
Sequencing Primer
(F):5'- AAGTGCTCTCGGCCACTCAG -3'
(R):5'- CAAAACTGGGTTTTTGATAGCTGG -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation