Incidental Mutation 'R7326:Dnah14'
| ID |
568856 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dnah14
|
| Ensembl Gene |
ENSMUSG00000047369 |
| Gene Name |
dynein, axonemal, heavy chain 14 |
| Synonyms |
A230079K17Rik, Dnahc14, Gm980, LOC381311 |
| MMRRC Submission |
045378-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.074)
|
| Stock # |
R7326 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
181404158-181642306 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 181425968 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Valine
at position 171
(M171V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000146843
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000208001]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000208001
AA Change: M171V
PolyPhen 2
Score 0.016 (Sensitivity: 0.95; Specificity: 0.79)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. DNAH14 is an axonemal dynein heavy chain (DHC) (Vaughan et al., 1996 [PubMed 8812413]).[supplied by OMIM, Mar 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 112 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb4 |
T |
C |
5: 8,984,226 (GRCm39) |
V652A |
probably benign |
Het |
| Acvrl1 |
G |
T |
15: 101,038,953 (GRCm39) |
V417L |
probably damaging |
Het |
| Add1 |
A |
G |
5: 34,776,715 (GRCm39) |
R479G |
probably benign |
Het |
| Adgb |
A |
T |
10: 10,276,318 (GRCm39) |
L350Q |
possibly damaging |
Het |
| Adgrl2 |
A |
T |
3: 148,552,506 (GRCm39) |
S666T |
probably benign |
Het |
| Akap9 |
T |
A |
5: 4,095,930 (GRCm39) |
D2268E |
possibly damaging |
Het |
| Amigo3 |
C |
A |
9: 107,931,265 (GRCm39) |
H229Q |
probably benign |
Het |
| Ano6 |
G |
C |
15: 95,762,125 (GRCm39) |
Q31H |
possibly damaging |
Het |
| Ap4m1 |
G |
A |
5: 138,173,281 (GRCm39) |
D180N |
probably damaging |
Het |
| Apc2 |
A |
T |
10: 80,147,574 (GRCm39) |
D876V |
probably damaging |
Het |
| Apcdd1 |
T |
A |
18: 63,085,259 (GRCm39) |
Y485* |
probably null |
Het |
| Aqp1 |
G |
T |
6: 55,313,836 (GRCm39) |
D121Y |
probably benign |
Het |
| Bicd2 |
C |
A |
13: 49,523,085 (GRCm39) |
R141S |
probably benign |
Het |
| Brpf3 |
C |
A |
17: 29,025,267 (GRCm39) |
H113Q |
probably benign |
Het |
| Cacng2 |
A |
T |
15: 77,897,520 (GRCm39) |
Y96* |
probably null |
Het |
| Catsperg1 |
G |
T |
7: 28,910,184 (GRCm39) |
N52K |
possibly damaging |
Het |
| Celsr2 |
A |
C |
3: 108,302,311 (GRCm39) |
F2606V |
possibly damaging |
Het |
| Cerkl |
A |
T |
2: 79,162,949 (GRCm39) |
N516K |
probably benign |
Het |
| Ciita |
G |
A |
16: 10,330,152 (GRCm39) |
R812H |
probably damaging |
Het |
| Cldn3 |
T |
A |
5: 135,015,837 (GRCm39) |
L180Q |
probably damaging |
Het |
| Cnot6l |
T |
C |
5: 96,225,158 (GRCm39) |
I512V |
probably benign |
Het |
| Col5a2 |
A |
T |
1: 45,482,027 (GRCm39) |
D32E |
unknown |
Het |
| Coro7 |
A |
G |
16: 4,449,912 (GRCm39) |
V616A |
probably damaging |
Het |
| Cyp4f18 |
T |
C |
8: 72,742,498 (GRCm39) |
D494G |
probably benign |
Het |
| Ddx39a |
T |
A |
8: 84,449,100 (GRCm39) |
V296E |
probably benign |
Het |
| Dgkg |
A |
T |
16: 22,367,440 (GRCm39) |
H593Q |
probably damaging |
Het |
| Dhx16 |
T |
C |
17: 36,197,052 (GRCm39) |
L645P |
probably damaging |
Het |
| Dnhd1 |
G |
A |
7: 105,370,137 (GRCm39) |
V4521I |
probably damaging |
Het |
| Dok7 |
A |
T |
5: 35,221,866 (GRCm39) |
M60L |
probably benign |
Het |
| Donson |
A |
T |
16: 91,485,599 (GRCm39) |
M1K |
probably null |
Het |
| Dsp |
C |
T |
13: 38,376,859 (GRCm39) |
T1548M |
probably benign |
Het |
| Dyrk1a |
A |
G |
16: 94,492,902 (GRCm39) |
T712A |
probably damaging |
Het |
| Eef2 |
A |
G |
10: 81,017,116 (GRCm39) |
T708A |
probably benign |
Het |
| Epn3 |
G |
A |
11: 94,384,606 (GRCm39) |
T289I |
probably benign |
Het |
| Fam171a1 |
C |
T |
2: 3,227,509 (GRCm39) |
R881* |
probably null |
Het |
| Fat2 |
T |
A |
11: 55,173,130 (GRCm39) |
R2528W |
probably damaging |
Het |
| Fbxl9 |
T |
C |
8: 106,039,530 (GRCm39) |
D127G |
probably damaging |
Het |
| Fgfr1 |
T |
G |
8: 26,063,855 (GRCm39) |
F707C |
probably damaging |
Het |
| Frem2 |
G |
C |
3: 53,562,174 (GRCm39) |
P778A |
probably damaging |
Het |
| Ganc |
A |
G |
2: 120,261,080 (GRCm39) |
Y255C |
probably damaging |
Het |
| Garin4 |
G |
A |
1: 190,896,550 (GRCm39) |
T31M |
probably benign |
Het |
| Ginm1 |
A |
T |
10: 7,653,614 (GRCm39) |
Y65* |
probably null |
Het |
| Gm11559 |
T |
A |
11: 99,755,707 (GRCm39) |
C119S |
unknown |
Het |
| Gnai1 |
T |
A |
5: 18,494,549 (GRCm39) |
H188L |
|
Het |
| H2bc6 |
T |
C |
13: 23,769,906 (GRCm39) |
K12E |
probably benign |
Het |
| H6pd |
C |
T |
4: 150,080,807 (GRCm39) |
A13T |
probably benign |
Het |
| Hoxd12 |
A |
T |
2: 74,505,590 (GRCm39) |
T54S |
possibly damaging |
Het |
| Hs3st5 |
T |
A |
10: 36,709,190 (GRCm39) |
L242M |
probably damaging |
Het |
| Il9r |
C |
A |
11: 32,144,389 (GRCm39) |
V139L |
possibly damaging |
Het |
| Immt |
A |
G |
6: 71,823,353 (GRCm39) |
D68G |
probably damaging |
Het |
| Itsn2 |
A |
G |
12: 4,682,985 (GRCm39) |
I304V |
unknown |
Het |
| Lgr4 |
G |
A |
2: 109,826,974 (GRCm39) |
W159* |
probably null |
Het |
| Lin52 |
G |
A |
12: 84,504,728 (GRCm39) |
G38S |
probably damaging |
Het |
| Lpgat1 |
A |
T |
1: 191,451,565 (GRCm39) |
M64L |
probably benign |
Het |
| Lrrc10b |
G |
T |
19: 10,434,142 (GRCm39) |
R180S |
possibly damaging |
Het |
| Lrrc36 |
A |
T |
8: 106,176,401 (GRCm39) |
L258F |
possibly damaging |
Het |
| Ltbp4 |
T |
A |
7: 27,029,180 (GRCm39) |
Q235L |
unknown |
Het |
| Maml2 |
A |
G |
9: 13,532,903 (GRCm39) |
M706V |
|
Het |
| Mc5r |
G |
T |
18: 68,472,739 (GRCm39) |
C366F |
probably damaging |
Het |
| Mlip |
T |
C |
9: 77,072,124 (GRCm39) |
R244G |
probably benign |
Het |
| Muc16 |
T |
A |
9: 18,496,309 (GRCm39) |
R6658S |
probably benign |
Het |
| Mup4 |
G |
T |
4: 59,960,046 (GRCm39) |
H73N |
possibly damaging |
Het |
| Nf1 |
A |
G |
11: 79,455,769 (GRCm39) |
M565V |
probably benign |
Het |
| Nphp1 |
G |
A |
2: 127,603,137 (GRCm39) |
T382I |
possibly damaging |
Het |
| Nrcam |
C |
T |
12: 44,610,809 (GRCm39) |
T503I |
possibly damaging |
Het |
| Nwd2 |
A |
T |
5: 63,957,752 (GRCm39) |
N361Y |
probably damaging |
Het |
| Or10a3 |
A |
T |
7: 108,480,023 (GRCm39) |
H263Q |
probably damaging |
Het |
| Or4f15 |
A |
T |
2: 111,813,672 (GRCm39) |
L249* |
probably null |
Het |
| Or5ak23 |
A |
T |
2: 85,244,788 (GRCm39) |
V145E |
probably damaging |
Het |
| Or6f1 |
A |
G |
7: 85,970,782 (GRCm39) |
I126T |
probably damaging |
Het |
| Or7g21 |
A |
G |
9: 19,032,965 (GRCm39) |
Y235C |
probably benign |
Het |
| Or8j3 |
A |
G |
2: 86,028,917 (GRCm39) |
Y60H |
probably damaging |
Het |
| Or9a7 |
G |
T |
6: 40,521,829 (GRCm39) |
A28E |
probably damaging |
Het |
| Orc5 |
A |
G |
5: 22,728,582 (GRCm39) |
F308L |
probably benign |
Het |
| Padi1 |
T |
A |
4: 140,559,715 (GRCm39) |
Y54F |
probably benign |
Het |
| Parp1 |
A |
G |
1: 180,396,665 (GRCm39) |
K23E |
possibly damaging |
Het |
| Pate1 |
A |
T |
9: 35,597,268 (GRCm39) |
V79D |
possibly damaging |
Het |
| Pcdh18 |
T |
C |
3: 49,711,309 (GRCm39) |
H2R |
probably benign |
Het |
| Pcnx2 |
G |
A |
8: 126,613,822 (GRCm39) |
S543F |
probably damaging |
Het |
| Pcp4l1 |
G |
A |
1: 171,002,034 (GRCm39) |
A42V |
possibly damaging |
Het |
| Pnkp |
T |
A |
7: 44,509,158 (GRCm39) |
F169L |
probably damaging |
Het |
| Ppp6r3 |
A |
T |
19: 3,557,325 (GRCm39) |
N254K |
probably damaging |
Het |
| Psd |
A |
G |
19: 46,312,893 (GRCm39) |
L159P |
probably benign |
Het |
| Ptprf |
A |
G |
4: 118,088,866 (GRCm39) |
Y646H |
probably damaging |
Het |
| Rab3ip |
A |
T |
10: 116,773,538 (GRCm39) |
S92T |
probably benign |
Het |
| Rabgef1 |
A |
G |
5: 130,216,192 (GRCm39) |
|
probably benign |
Het |
| Ralgapa1 |
C |
A |
12: 55,755,789 (GRCm39) |
W1129L |
probably damaging |
Het |
| Rhpn2 |
T |
A |
7: 35,084,888 (GRCm39) |
L594Q |
probably benign |
Het |
| Rnf38 |
C |
A |
4: 44,158,989 (GRCm39) |
|
probably benign |
Het |
| Ryr2 |
T |
A |
13: 11,753,080 (GRCm39) |
H1747L |
possibly damaging |
Het |
| Sec16a |
A |
G |
2: 26,329,729 (GRCm39) |
L13P |
unknown |
Het |
| Spef1l |
A |
T |
7: 139,558,458 (GRCm39) |
|
probably null |
Het |
| Sppl3 |
C |
A |
5: 115,220,394 (GRCm39) |
T102K |
probably damaging |
Het |
| Srgap2 |
A |
T |
1: 131,219,351 (GRCm39) |
Y264* |
probably null |
Het |
| Stxbp2 |
T |
C |
8: 3,691,151 (GRCm39) |
M465T |
|
Het |
| Sumf2 |
A |
G |
5: 129,891,551 (GRCm39) |
K305R |
probably benign |
Het |
| Susd2 |
T |
A |
10: 75,478,399 (GRCm39) |
Y59F |
probably benign |
Het |
| Taco1 |
T |
C |
11: 105,963,443 (GRCm39) |
V198A |
probably benign |
Het |
| Tas2r136 |
A |
T |
6: 132,754,869 (GRCm39) |
M86K |
possibly damaging |
Het |
| Tbc1d10c |
T |
C |
19: 4,234,897 (GRCm39) |
E388G |
possibly damaging |
Het |
| Tmem132c |
C |
T |
5: 127,641,123 (GRCm39) |
T1098I |
possibly damaging |
Het |
| Trim3 |
G |
T |
7: 105,267,007 (GRCm39) |
Y457* |
probably null |
Het |
| Ttc38 |
A |
G |
15: 85,737,062 (GRCm39) |
T316A |
probably benign |
Het |
| Ubqln4 |
T |
A |
3: 88,463,217 (GRCm39) |
N127K |
probably benign |
Het |
| Wdr91 |
A |
T |
6: 34,881,561 (GRCm39) |
F262Y |
probably damaging |
Het |
| Zdhhc6 |
A |
T |
19: 55,291,187 (GRCm39) |
C343S |
possibly damaging |
Het |
| Zfp248 |
A |
G |
6: 118,407,170 (GRCm39) |
C140R |
probably damaging |
Het |
| Zfp266 |
T |
C |
9: 20,413,391 (GRCm39) |
T90A |
probably benign |
Het |
| Zfp407 |
A |
T |
18: 84,577,167 (GRCm39) |
D1315E |
possibly damaging |
Het |
| Zfp644 |
T |
C |
5: 106,786,143 (GRCm39) |
S135G |
probably benign |
Het |
| Zscan29 |
A |
T |
2: 120,991,469 (GRCm39) |
I773N |
probably damaging |
Het |
| Zswim5 |
T |
A |
4: 116,838,031 (GRCm39) |
V787E |
possibly damaging |
Het |
|
| Other mutations in Dnah14 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01086:Dnah14
|
APN |
1 |
181,579,611 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL01764:Dnah14
|
APN |
1 |
181,572,342 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03218:Dnah14
|
APN |
1 |
181,582,834 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03290:Dnah14
|
APN |
1 |
181,591,543 (GRCm39) |
splice site |
probably benign |
|
|
IGL03384:Dnah14
|
APN |
1 |
181,573,514 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0009:Dnah14
|
UTSW |
1 |
181,596,972 (GRCm39) |
splice site |
probably benign |
|
|
R0125:Dnah14
|
UTSW |
1 |
181,579,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0579:Dnah14
|
UTSW |
1 |
181,572,312 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R0973:Dnah14
|
UTSW |
1 |
181,579,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Dnah14
|
UTSW |
1 |
181,579,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0974:Dnah14
|
UTSW |
1 |
181,579,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1609:Dnah14
|
UTSW |
1 |
181,577,742 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1860:Dnah14
|
UTSW |
1 |
181,591,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2050:Dnah14
|
UTSW |
1 |
181,580,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2974:Dnah14
|
UTSW |
1 |
181,582,806 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4715:Dnah14
|
UTSW |
1 |
181,584,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5076:Dnah14
|
UTSW |
1 |
181,584,799 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5424:Dnah14
|
UTSW |
1 |
181,590,875 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5808:Dnah14
|
UTSW |
1 |
181,568,724 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R5997:Dnah14
|
UTSW |
1 |
181,597,670 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6052:Dnah14
|
UTSW |
1 |
181,494,052 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6061:Dnah14
|
UTSW |
1 |
181,536,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6089:Dnah14
|
UTSW |
1 |
181,577,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6092:Dnah14
|
UTSW |
1 |
181,449,398 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6145:Dnah14
|
UTSW |
1 |
181,493,982 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6163:Dnah14
|
UTSW |
1 |
181,493,926 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6246:Dnah14
|
UTSW |
1 |
181,508,453 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6302:Dnah14
|
UTSW |
1 |
181,428,771 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6306:Dnah14
|
UTSW |
1 |
181,412,589 (GRCm39) |
frame shift |
probably null |
|
|
R6326:Dnah14
|
UTSW |
1 |
181,611,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6348:Dnah14
|
UTSW |
1 |
181,454,285 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6367:Dnah14
|
UTSW |
1 |
181,582,951 (GRCm39) |
splice site |
probably null |
|
|
R6376:Dnah14
|
UTSW |
1 |
181,433,459 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R6389:Dnah14
|
UTSW |
1 |
181,478,767 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6433:Dnah14
|
UTSW |
1 |
181,479,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6454:Dnah14
|
UTSW |
1 |
181,611,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6476:Dnah14
|
UTSW |
1 |
181,572,333 (GRCm39) |
missense |
probably benign |
0.26 |
|
R6523:Dnah14
|
UTSW |
1 |
181,471,186 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6529:Dnah14
|
UTSW |
1 |
181,494,034 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6538:Dnah14
|
UTSW |
1 |
181,412,550 (GRCm39) |
missense |
unknown |
|
|
R6546:Dnah14
|
UTSW |
1 |
181,566,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6752:Dnah14
|
UTSW |
1 |
181,421,017 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6762:Dnah14
|
UTSW |
1 |
181,584,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6786:Dnah14
|
UTSW |
1 |
181,468,970 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6849:Dnah14
|
UTSW |
1 |
181,636,510 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6877:Dnah14
|
UTSW |
1 |
181,455,997 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6912:Dnah14
|
UTSW |
1 |
181,577,748 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6919:Dnah14
|
UTSW |
1 |
181,412,631 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6924:Dnah14
|
UTSW |
1 |
181,455,517 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6957:Dnah14
|
UTSW |
1 |
181,612,740 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6980:Dnah14
|
UTSW |
1 |
181,475,795 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7018:Dnah14
|
UTSW |
1 |
181,454,509 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R7046:Dnah14
|
UTSW |
1 |
181,450,568 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7058:Dnah14
|
UTSW |
1 |
181,525,614 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7068:Dnah14
|
UTSW |
1 |
181,597,355 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7115:Dnah14
|
UTSW |
1 |
181,547,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7130:Dnah14
|
UTSW |
1 |
181,573,523 (GRCm39) |
nonsense |
probably null |
|
|
R7165:Dnah14
|
UTSW |
1 |
181,532,100 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7169:Dnah14
|
UTSW |
1 |
181,529,930 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7184:Dnah14
|
UTSW |
1 |
181,532,094 (GRCm39) |
nonsense |
probably null |
|
|
R7232:Dnah14
|
UTSW |
1 |
181,584,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7260:Dnah14
|
UTSW |
1 |
181,534,309 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7276:Dnah14
|
UTSW |
1 |
181,513,372 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7290:Dnah14
|
UTSW |
1 |
181,455,739 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7314:Dnah14
|
UTSW |
1 |
181,612,819 (GRCm39) |
splice site |
probably null |
|
|
R7336:Dnah14
|
UTSW |
1 |
181,625,299 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7363:Dnah14
|
UTSW |
1 |
181,518,089 (GRCm39) |
splice site |
probably null |
|
|
R7371:Dnah14
|
UTSW |
1 |
181,454,450 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7376:Dnah14
|
UTSW |
1 |
181,590,967 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7418:Dnah14
|
UTSW |
1 |
181,444,307 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7473:Dnah14
|
UTSW |
1 |
181,579,704 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7514:Dnah14
|
UTSW |
1 |
181,455,632 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7555:Dnah14
|
UTSW |
1 |
181,597,619 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7641:Dnah14
|
UTSW |
1 |
181,535,098 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7663:Dnah14
|
UTSW |
1 |
181,579,720 (GRCm39) |
splice site |
probably null |
|
|
R7674:Dnah14
|
UTSW |
1 |
181,535,098 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7680:Dnah14
|
UTSW |
1 |
181,513,365 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7709:Dnah14
|
UTSW |
1 |
181,530,049 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7842:Dnah14
|
UTSW |
1 |
181,455,463 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7861:Dnah14
|
UTSW |
1 |
181,444,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7988:Dnah14
|
UTSW |
1 |
181,611,139 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8016:Dnah14
|
UTSW |
1 |
181,475,876 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8042:Dnah14
|
UTSW |
1 |
181,471,196 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8071:Dnah14
|
UTSW |
1 |
181,443,459 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8086:Dnah14
|
UTSW |
1 |
181,593,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8095:Dnah14
|
UTSW |
1 |
181,633,597 (GRCm39) |
nonsense |
probably null |
|
|
R8139:Dnah14
|
UTSW |
1 |
181,582,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8176:Dnah14
|
UTSW |
1 |
181,484,598 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8193:Dnah14
|
UTSW |
1 |
181,515,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8197:Dnah14
|
UTSW |
1 |
181,517,666 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8209:Dnah14
|
UTSW |
1 |
181,623,110 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R8226:Dnah14
|
UTSW |
1 |
181,623,110 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R8251:Dnah14
|
UTSW |
1 |
181,492,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8264:Dnah14
|
UTSW |
1 |
181,572,357 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8284:Dnah14
|
UTSW |
1 |
181,601,376 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8289:Dnah14
|
UTSW |
1 |
181,543,780 (GRCm39) |
nonsense |
probably null |
|
|
R8323:Dnah14
|
UTSW |
1 |
181,532,109 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8442:Dnah14
|
UTSW |
1 |
181,568,849 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8458:Dnah14
|
UTSW |
1 |
181,633,577 (GRCm39) |
missense |
|
|
|
R8507:Dnah14
|
UTSW |
1 |
181,468,979 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8509:Dnah14
|
UTSW |
1 |
181,642,220 (GRCm39) |
missense |
|
|
|
R8520:Dnah14
|
UTSW |
1 |
181,481,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8530:Dnah14
|
UTSW |
1 |
181,492,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8703:Dnah14
|
UTSW |
1 |
181,493,576 (GRCm39) |
nonsense |
probably null |
|
|
R8710:Dnah14
|
UTSW |
1 |
181,517,876 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8752:Dnah14
|
UTSW |
1 |
181,455,581 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8792:Dnah14
|
UTSW |
1 |
181,642,189 (GRCm39) |
missense |
|
|
|
R8797:Dnah14
|
UTSW |
1 |
181,465,412 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8821:Dnah14
|
UTSW |
1 |
181,619,569 (GRCm39) |
nonsense |
probably null |
|
|
R8834:Dnah14
|
UTSW |
1 |
181,444,315 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8913:Dnah14
|
UTSW |
1 |
181,553,063 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8925:Dnah14
|
UTSW |
1 |
181,508,321 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8927:Dnah14
|
UTSW |
1 |
181,508,321 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8934:Dnah14
|
UTSW |
1 |
181,450,288 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9090:Dnah14
|
UTSW |
1 |
181,597,325 (GRCm39) |
missense |
probably benign |
0.33 |
|
R9169:Dnah14
|
UTSW |
1 |
181,433,381 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9199:Dnah14
|
UTSW |
1 |
181,478,566 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R9212:Dnah14
|
UTSW |
1 |
181,628,852 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9213:Dnah14
|
UTSW |
1 |
181,444,205 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9271:Dnah14
|
UTSW |
1 |
181,597,325 (GRCm39) |
missense |
probably benign |
0.33 |
|
R9282:Dnah14
|
UTSW |
1 |
181,642,077 (GRCm39) |
missense |
|
|
|
R9350:Dnah14
|
UTSW |
1 |
181,562,369 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R9358:Dnah14
|
UTSW |
1 |
181,536,598 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9436:Dnah14
|
UTSW |
1 |
181,508,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9484:Dnah14
|
UTSW |
1 |
181,625,311 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9484:Dnah14
|
UTSW |
1 |
181,517,773 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9486:Dnah14
|
UTSW |
1 |
181,508,494 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9546:Dnah14
|
UTSW |
1 |
181,420,992 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9547:Dnah14
|
UTSW |
1 |
181,420,992 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9578:Dnah14
|
UTSW |
1 |
181,502,007 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9654:Dnah14
|
UTSW |
1 |
181,593,904 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9681:Dnah14
|
UTSW |
1 |
181,562,414 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9683:Dnah14
|
UTSW |
1 |
181,426,509 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9687:Dnah14
|
UTSW |
1 |
181,425,978 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9718:Dnah14
|
UTSW |
1 |
181,450,544 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9751:Dnah14
|
UTSW |
1 |
181,619,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9757:Dnah14
|
UTSW |
1 |
181,513,349 (GRCm39) |
missense |
probably benign |
0.03 |
|
RF007:Dnah14
|
UTSW |
1 |
181,513,374 (GRCm39) |
missense |
probably benign |
0.00 |
|
RF012:Dnah14
|
UTSW |
1 |
181,455,463 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Dnah14
|
UTSW |
1 |
181,584,916 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
Z1177:Dnah14
|
UTSW |
1 |
181,517,885 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1177:Dnah14
|
UTSW |
1 |
181,593,869 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Dnah14
|
UTSW |
1 |
181,590,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTTTCTGTAGAAGCACAAGAAAGC -3'
(R):5'- TCTGCTTGACTGCAACATCC -3'
Sequencing Primer
(F):5'- TGTAGAAGCACAAGAAAGCAAGCTG -3'
(R):5'- CATATACACGCGTTTCCT -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation