Mutagenetix > Incidental Mutation

Incidental Mutation 'R7326:Dnhd1'

568908

Institutional Source

Beutler Lab

Gene Symbol

Dnhd1

Ensembl Gene

ENSMUSG00000030882

Gene Name

dynein heavy chain domain 1

Synonyms

8030491N06Rik

MMRRC Submission

045378-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.090) question?

Stock #

R7326 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

105300034-105371006 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 105370137 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Isoleucine at position 4521 (V4521I)

Ref Sequence

ENSEMBL: ENSMUSP00000121261 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000145988]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000145988
AA Change: V4521I

PolyPhen 2 Score 0.959 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000121261
Gene: ENSMUSG00000030882
AA Change: V4521I

Domain	Start	End	E-Value	Type
low complexity region	5	18	N/A	INTRINSIC
low complexity region	102	115	N/A	INTRINSIC
low complexity region	183	191	N/A	INTRINSIC
low complexity region	253	269	N/A	INTRINSIC
low complexity region	943	962	N/A	INTRINSIC
Pfam:DHC_N2	1018	1472	4.6e-50	PFAM
Pfam:AAA_6	1652	1875	2.7e-14	PFAM
low complexity region	1906	1918	N/A	INTRINSIC
Blast:AAA	1993	2196	1e-34	BLAST
Pfam:AAA_7	2362	2610	3.3e-11	PFAM
low complexity region	2697	2714	N/A	INTRINSIC
low complexity region	2722	2733	N/A	INTRINSIC
low complexity region	2800	2810	N/A	INTRINSIC
low complexity region	3116	3134	N/A	INTRINSIC
Pfam:MT	3178	3470	3.9e-16	PFAM
coiled coil region	3590	3642	N/A	INTRINSIC
coiled coil region	3816	3843	N/A	INTRINSIC
Pfam:Dynein_heavy	3976	4746	7.3e-97	PFAM

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.2%

Validation Efficiency

Allele List at MGI

All alleles(1) : Gene trapped(1)

Other mutations in this stock

Total: 112 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb4	T	C	5: 8,984,226 (GRCm39)	V652A	probably benign	Het
Acvrl1	G	T	15: 101,038,953 (GRCm39)	V417L	probably damaging	Het
Add1	A	G	5: 34,776,715 (GRCm39)	R479G	probably benign	Het
Adgb	A	T	10: 10,276,318 (GRCm39)	L350Q	possibly damaging	Het
Adgrl2	A	T	3: 148,552,506 (GRCm39)	S666T	probably benign	Het
Akap9	T	A	5: 4,095,930 (GRCm39)	D2268E	possibly damaging	Het
Amigo3	C	A	9: 107,931,265 (GRCm39)	H229Q	probably benign	Het
Ano6	G	C	15: 95,762,125 (GRCm39)	Q31H	possibly damaging	Het
Ap4m1	G	A	5: 138,173,281 (GRCm39)	D180N	probably damaging	Het
Apc2	A	T	10: 80,147,574 (GRCm39)	D876V	probably damaging	Het
Apcdd1	T	A	18: 63,085,259 (GRCm39)	Y485*	probably null	Het
Aqp1	G	T	6: 55,313,836 (GRCm39)	D121Y	probably benign	Het
Bicd2	C	A	13: 49,523,085 (GRCm39)	R141S	probably benign	Het
Brpf3	C	A	17: 29,025,267 (GRCm39)	H113Q	probably benign	Het
Cacng2	A	T	15: 77,897,520 (GRCm39)	Y96*	probably null	Het
Catsperg1	G	T	7: 28,910,184 (GRCm39)	N52K	possibly damaging	Het
Celsr2	A	C	3: 108,302,311 (GRCm39)	F2606V	possibly damaging	Het
Cerkl	A	T	2: 79,162,949 (GRCm39)	N516K	probably benign	Het
Ciita	G	A	16: 10,330,152 (GRCm39)	R812H	probably damaging	Het
Cldn3	T	A	5: 135,015,837 (GRCm39)	L180Q	probably damaging	Het
Cnot6l	T	C	5: 96,225,158 (GRCm39)	I512V	probably benign	Het
Col5a2	A	T	1: 45,482,027 (GRCm39)	D32E	unknown	Het
Coro7	A	G	16: 4,449,912 (GRCm39)	V616A	probably damaging	Het
Cyp4f18	T	C	8: 72,742,498 (GRCm39)	D494G	probably benign	Het
Ddx39a	T	A	8: 84,449,100 (GRCm39)	V296E	probably benign	Het
Dgkg	A	T	16: 22,367,440 (GRCm39)	H593Q	probably damaging	Het
Dhx16	T	C	17: 36,197,052 (GRCm39)	L645P	probably damaging	Het
Dnah14	A	G	1: 181,425,968 (GRCm39)	M171V	probably benign	Het
Dok7	A	T	5: 35,221,866 (GRCm39)	M60L	probably benign	Het
Donson	A	T	16: 91,485,599 (GRCm39)	M1K	probably null	Het
Dsp	C	T	13: 38,376,859 (GRCm39)	T1548M	probably benign	Het
Dyrk1a	A	G	16: 94,492,902 (GRCm39)	T712A	probably damaging	Het
Eef2	A	G	10: 81,017,116 (GRCm39)	T708A	probably benign	Het
Epn3	G	A	11: 94,384,606 (GRCm39)	T289I	probably benign	Het
Fam171a1	C	T	2: 3,227,509 (GRCm39)	R881*	probably null	Het
Fat2	T	A	11: 55,173,130 (GRCm39)	R2528W	probably damaging	Het
Fbxl9	T	C	8: 106,039,530 (GRCm39)	D127G	probably damaging	Het
Fgfr1	T	G	8: 26,063,855 (GRCm39)	F707C	probably damaging	Het
Frem2	G	C	3: 53,562,174 (GRCm39)	P778A	probably damaging	Het
Ganc	A	G	2: 120,261,080 (GRCm39)	Y255C	probably damaging	Het
Garin4	G	A	1: 190,896,550 (GRCm39)	T31M	probably benign	Het
Ginm1	A	T	10: 7,653,614 (GRCm39)	Y65*	probably null	Het
Gm11559	T	A	11: 99,755,707 (GRCm39)	C119S	unknown	Het
Gnai1	T	A	5: 18,494,549 (GRCm39)	H188L		Het
H2bc6	T	C	13: 23,769,906 (GRCm39)	K12E	probably benign	Het
H6pd	C	T	4: 150,080,807 (GRCm39)	A13T	probably benign	Het
Hoxd12	A	T	2: 74,505,590 (GRCm39)	T54S	possibly damaging	Het
Hs3st5	T	A	10: 36,709,190 (GRCm39)	L242M	probably damaging	Het
Il9r	C	A	11: 32,144,389 (GRCm39)	V139L	possibly damaging	Het
Immt	A	G	6: 71,823,353 (GRCm39)	D68G	probably damaging	Het
Itsn2	A	G	12: 4,682,985 (GRCm39)	I304V	unknown	Het
Lgr4	G	A	2: 109,826,974 (GRCm39)	W159*	probably null	Het
Lin52	G	A	12: 84,504,728 (GRCm39)	G38S	probably damaging	Het
Lpgat1	A	T	1: 191,451,565 (GRCm39)	M64L	probably benign	Het
Lrrc10b	G	T	19: 10,434,142 (GRCm39)	R180S	possibly damaging	Het
Lrrc36	A	T	8: 106,176,401 (GRCm39)	L258F	possibly damaging	Het
Ltbp4	T	A	7: 27,029,180 (GRCm39)	Q235L	unknown	Het
Maml2	A	G	9: 13,532,903 (GRCm39)	M706V		Het
Mc5r	G	T	18: 68,472,739 (GRCm39)	C366F	probably damaging	Het
Mlip	T	C	9: 77,072,124 (GRCm39)	R244G	probably benign	Het
Muc16	T	A	9: 18,496,309 (GRCm39)	R6658S	probably benign	Het
Mup4	G	T	4: 59,960,046 (GRCm39)	H73N	possibly damaging	Het
Nf1	A	G	11: 79,455,769 (GRCm39)	M565V	probably benign	Het
Nphp1	G	A	2: 127,603,137 (GRCm39)	T382I	possibly damaging	Het
Nrcam	C	T	12: 44,610,809 (GRCm39)	T503I	possibly damaging	Het
Nwd2	A	T	5: 63,957,752 (GRCm39)	N361Y	probably damaging	Het
Or10a3	A	T	7: 108,480,023 (GRCm39)	H263Q	probably damaging	Het
Or4f15	A	T	2: 111,813,672 (GRCm39)	L249*	probably null	Het
Or5ak23	A	T	2: 85,244,788 (GRCm39)	V145E	probably damaging	Het
Or6f1	A	G	7: 85,970,782 (GRCm39)	I126T	probably damaging	Het
Or7g21	A	G	9: 19,032,965 (GRCm39)	Y235C	probably benign	Het
Or8j3	A	G	2: 86,028,917 (GRCm39)	Y60H	probably damaging	Het
Or9a7	G	T	6: 40,521,829 (GRCm39)	A28E	probably damaging	Het
Orc5	A	G	5: 22,728,582 (GRCm39)	F308L	probably benign	Het
Padi1	T	A	4: 140,559,715 (GRCm39)	Y54F	probably benign	Het
Parp1	A	G	1: 180,396,665 (GRCm39)	K23E	possibly damaging	Het
Pate1	A	T	9: 35,597,268 (GRCm39)	V79D	possibly damaging	Het
Pcdh18	T	C	3: 49,711,309 (GRCm39)	H2R	probably benign	Het
Pcnx2	G	A	8: 126,613,822 (GRCm39)	S543F	probably damaging	Het
Pcp4l1	G	A	1: 171,002,034 (GRCm39)	A42V	possibly damaging	Het
Pnkp	T	A	7: 44,509,158 (GRCm39)	F169L	probably damaging	Het
Ppp6r3	A	T	19: 3,557,325 (GRCm39)	N254K	probably damaging	Het
Psd	A	G	19: 46,312,893 (GRCm39)	L159P	probably benign	Het
Ptprf	A	G	4: 118,088,866 (GRCm39)	Y646H	probably damaging	Het
Rab3ip	A	T	10: 116,773,538 (GRCm39)	S92T	probably benign	Het
Rabgef1	A	G	5: 130,216,192 (GRCm39)		probably benign	Het
Ralgapa1	C	A	12: 55,755,789 (GRCm39)	W1129L	probably damaging	Het
Rhpn2	T	A	7: 35,084,888 (GRCm39)	L594Q	probably benign	Het
Rnf38	C	A	4: 44,158,989 (GRCm39)		probably benign	Het
Ryr2	T	A	13: 11,753,080 (GRCm39)	H1747L	possibly damaging	Het
Sec16a	A	G	2: 26,329,729 (GRCm39)	L13P	unknown	Het
Spef1l	A	T	7: 139,558,458 (GRCm39)		probably null	Het
Sppl3	C	A	5: 115,220,394 (GRCm39)	T102K	probably damaging	Het
Srgap2	A	T	1: 131,219,351 (GRCm39)	Y264*	probably null	Het
Stxbp2	T	C	8: 3,691,151 (GRCm39)	M465T		Het
Sumf2	A	G	5: 129,891,551 (GRCm39)	K305R	probably benign	Het
Susd2	T	A	10: 75,478,399 (GRCm39)	Y59F	probably benign	Het
Taco1	T	C	11: 105,963,443 (GRCm39)	V198A	probably benign	Het
Tas2r136	A	T	6: 132,754,869 (GRCm39)	M86K	possibly damaging	Het
Tbc1d10c	T	C	19: 4,234,897 (GRCm39)	E388G	possibly damaging	Het
Tmem132c	C	T	5: 127,641,123 (GRCm39)	T1098I	possibly damaging	Het
Trim3	G	T	7: 105,267,007 (GRCm39)	Y457*	probably null	Het
Ttc38	A	G	15: 85,737,062 (GRCm39)	T316A	probably benign	Het
Ubqln4	T	A	3: 88,463,217 (GRCm39)	N127K	probably benign	Het
Wdr91	A	T	6: 34,881,561 (GRCm39)	F262Y	probably damaging	Het
Zdhhc6	A	T	19: 55,291,187 (GRCm39)	C343S	possibly damaging	Het
Zfp248	A	G	6: 118,407,170 (GRCm39)	C140R	probably damaging	Het
Zfp266	T	C	9: 20,413,391 (GRCm39)	T90A	probably benign	Het
Zfp407	A	T	18: 84,577,167 (GRCm39)	D1315E	possibly damaging	Het
Zfp644	T	C	5: 106,786,143 (GRCm39)	S135G	probably benign	Het
Zscan29	A	T	2: 120,991,469 (GRCm39)	I773N	probably damaging	Het
Zswim5	T	A	4: 116,838,031 (GRCm39)	V787E	possibly damaging	Het

Other mutations in Dnhd1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00321:Dnhd1	APN	7	105,327,202 (GRCm39)	missense	probably damaging	1.00
IGL00516:Dnhd1	APN	7	105,306,418 (GRCm39)	missense	possibly damaging	0.52
IGL00576:Dnhd1	APN	7	105,341,882 (GRCm39)	missense	probably damaging	1.00
IGL00990:Dnhd1	APN	7	105,370,895 (GRCm39)	missense	possibly damaging	0.85
IGL01346:Dnhd1	APN	7	105,363,116 (GRCm39)	missense	probably benign
IGL01714:Dnhd1	APN	7	105,370,149 (GRCm39)	missense	probably damaging	1.00
IGL01735:Dnhd1	APN	7	105,362,961 (GRCm39)	missense	probably benign	0.37
IGL01814:Dnhd1	APN	7	105,301,237 (GRCm39)	missense	probably benign
IGL01999:Dnhd1	APN	7	105,370,422 (GRCm39)	missense	possibly damaging	0.50
IGL02022:Dnhd1	APN	7	105,327,516 (GRCm39)	missense	probably damaging	1.00
IGL02131:Dnhd1	APN	7	105,370,009 (GRCm39)	missense	probably damaging	1.00
IGL02156:Dnhd1	APN	7	105,370,951 (GRCm39)	missense	probably damaging	1.00
IGL02674:Dnhd1	APN	7	105,370,688 (GRCm39)	missense	probably benign	0.00
IGL02966:Dnhd1	APN	7	105,369,948 (GRCm39)	missense	probably benign	0.00
IGL03066:Dnhd1	APN	7	105,369,089 (GRCm39)	missense	probably damaging	0.99
IGL03298:Dnhd1	APN	7	105,363,682 (GRCm39)	missense	probably damaging	0.98
IGL03378:Dnhd1	APN	7	105,362,940 (GRCm39)	missense	possibly damaging	0.87
IGL02802:Dnhd1	UTSW	7	105,304,930 (GRCm39)	missense	possibly damaging	0.83
R0060:Dnhd1	UTSW	7	105,317,721 (GRCm39)	missense	probably damaging	0.99
R0129:Dnhd1	UTSW	7	105,370,131 (GRCm39)	missense	probably benign	0.19
R0238:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0238:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0239:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0239:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0384:Dnhd1	UTSW	7	105,369,321 (GRCm39)	missense	possibly damaging	0.56
R0453:Dnhd1	UTSW	7	105,323,651 (GRCm39)	missense	probably benign	0.00
R0540:Dnhd1	UTSW	7	105,369,995 (GRCm39)	missense	probably benign	0.04
R0554:Dnhd1	UTSW	7	105,343,602 (GRCm39)	missense	probably benign	0.10
R0576:Dnhd1	UTSW	7	105,363,252 (GRCm39)	missense	probably damaging	1.00
R0607:Dnhd1	UTSW	7	105,369,995 (GRCm39)	missense	probably benign	0.04
R0631:Dnhd1	UTSW	7	105,300,831 (GRCm39)	missense	probably benign	0.17
R0639:Dnhd1	UTSW	7	105,345,671 (GRCm39)	missense	possibly damaging	0.95
R0668:Dnhd1	UTSW	7	105,344,958 (GRCm39)	missense	probably benign
R0669:Dnhd1	UTSW	7	105,342,911 (GRCm39)	missense	probably benign	0.01
R0670:Dnhd1	UTSW	7	105,345,671 (GRCm39)	missense	possibly damaging	0.95
R0699:Dnhd1	UTSW	7	105,301,113 (GRCm39)	missense	probably damaging	0.98
R1019:Dnhd1	UTSW	7	105,358,378 (GRCm39)	missense	probably damaging	1.00
R1144:Dnhd1	UTSW	7	105,362,238 (GRCm39)	missense	probably damaging	1.00
R1226:Dnhd1	UTSW	7	105,346,106 (GRCm39)	missense	probably damaging	1.00
R1257:Dnhd1	UTSW	7	105,343,360 (GRCm39)	missense	probably damaging	1.00
R1391:Dnhd1	UTSW	7	105,369,331 (GRCm39)	missense	probably damaging	1.00
R1453:Dnhd1	UTSW	7	105,370,480 (GRCm39)	critical splice donor site	probably null
R1501:Dnhd1	UTSW	7	105,317,670 (GRCm39)	missense	probably benign	0.00
R1503:Dnhd1	UTSW	7	105,342,867 (GRCm39)	missense	possibly damaging	0.67
R1515:Dnhd1	UTSW	7	105,353,355 (GRCm39)	missense	probably benign	0.11
R1615:Dnhd1	UTSW	7	105,362,913 (GRCm39)	missense	possibly damaging	0.74
R1615:Dnhd1	UTSW	7	105,352,413 (GRCm39)	missense	probably benign	0.00
R1656:Dnhd1	UTSW	7	105,363,488 (GRCm39)	missense	probably damaging	1.00
R1720:Dnhd1	UTSW	7	105,343,035 (GRCm39)	missense	probably benign
R1723:Dnhd1	UTSW	7	105,364,127 (GRCm39)	missense	possibly damaging	0.60
R1766:Dnhd1	UTSW	7	105,343,179 (GRCm39)	missense	possibly damaging	0.50
R1799:Dnhd1	UTSW	7	105,304,974 (GRCm39)	missense	probably benign	0.31
R1860:Dnhd1	UTSW	7	105,353,412 (GRCm39)	missense	probably benign
R1920:Dnhd1	UTSW	7	105,362,614 (GRCm39)	missense	probably benign	0.00
R1925:Dnhd1	UTSW	7	105,323,061 (GRCm39)	missense	probably damaging	0.96
R1925:Dnhd1	UTSW	7	105,301,459 (GRCm39)	missense	probably damaging	1.00
R1934:Dnhd1	UTSW	7	105,357,789 (GRCm39)	missense	probably benign	0.05
R1935:Dnhd1	UTSW	7	105,323,183 (GRCm39)	missense	probably benign	0.09
R1936:Dnhd1	UTSW	7	105,323,183 (GRCm39)	missense	probably benign	0.09
R2035:Dnhd1	UTSW	7	105,354,128 (GRCm39)	missense	probably damaging	0.99
R2125:Dnhd1	UTSW	7	105,327,178 (GRCm39)	missense	probably benign	0.35
R2127:Dnhd1	UTSW	7	105,342,928 (GRCm39)	missense	possibly damaging	0.56
R2254:Dnhd1	UTSW	7	105,352,979 (GRCm39)	missense	probably damaging	1.00
R2301:Dnhd1	UTSW	7	105,354,606 (GRCm39)	missense	probably damaging	1.00
R2316:Dnhd1	UTSW	7	105,323,628 (GRCm39)	missense	probably damaging	1.00
R2324:Dnhd1	UTSW	7	105,359,297 (GRCm39)	missense	probably damaging	1.00
R2337:Dnhd1	UTSW	7	105,352,674 (GRCm39)	missense	probably benign	0.07
R2381:Dnhd1	UTSW	7	105,342,871 (GRCm39)	missense	probably benign	0.42
R2394:Dnhd1	UTSW	7	105,369,438 (GRCm39)	missense	probably benign	0.19
R2862:Dnhd1	UTSW	7	105,361,766 (GRCm39)	missense	probably benign	0.01
R3038:Dnhd1	UTSW	7	105,369,436 (GRCm39)	missense	probably damaging	0.99
R3114:Dnhd1	UTSW	7	105,345,772 (GRCm39)	critical splice donor site	probably null
R3404:Dnhd1	UTSW	7	105,343,968 (GRCm39)	nonsense	probably null
R3405:Dnhd1	UTSW	7	105,343,968 (GRCm39)	nonsense	probably null
R3439:Dnhd1	UTSW	7	105,343,992 (GRCm39)	missense	probably damaging	1.00
R3959:Dnhd1	UTSW	7	105,362,329 (GRCm39)	missense	probably benign	0.21
R4014:Dnhd1	UTSW	7	105,364,045 (GRCm39)	missense	probably damaging	0.99
R4084:Dnhd1	UTSW	7	105,358,795 (GRCm39)	missense	probably damaging	1.00
R4181:Dnhd1	UTSW	7	105,343,161 (GRCm39)	missense	probably damaging	1.00
R4255:Dnhd1	UTSW	7	105,362,205 (GRCm39)	missense	probably damaging	1.00
R4302:Dnhd1	UTSW	7	105,343,161 (GRCm39)	missense	probably damaging	1.00
R4440:Dnhd1	UTSW	7	105,345,935 (GRCm39)	nonsense	probably null
R4565:Dnhd1	UTSW	7	105,301,163 (GRCm39)	missense	possibly damaging	0.92
R4569:Dnhd1	UTSW	7	105,306,373 (GRCm39)	splice site	probably null
R4584:Dnhd1	UTSW	7	105,327,256 (GRCm39)	missense	probably damaging	1.00
R4586:Dnhd1	UTSW	7	105,327,256 (GRCm39)	missense	probably damaging	1.00
R4590:Dnhd1	UTSW	7	105,363,237 (GRCm39)	missense	probably damaging	1.00
R4593:Dnhd1	UTSW	7	105,364,653 (GRCm39)	missense	probably benign	0.02
R4600:Dnhd1	UTSW	7	105,352,851 (GRCm39)	missense	probably damaging	1.00
R4705:Dnhd1	UTSW	7	105,304,948 (GRCm39)	missense	probably damaging	1.00
R4731:Dnhd1	UTSW	7	105,323,056 (GRCm39)	missense	probably benign	0.00
R4732:Dnhd1	UTSW	7	105,323,056 (GRCm39)	missense	probably benign	0.00
R4733:Dnhd1	UTSW	7	105,323,056 (GRCm39)	missense	probably benign	0.00
R4786:Dnhd1	UTSW	7	105,323,651 (GRCm39)	missense	probably benign	0.00
R4791:Dnhd1	UTSW	7	105,370,324 (GRCm39)	missense	probably damaging	1.00
R4811:Dnhd1	UTSW	7	105,363,488 (GRCm39)	missense	probably damaging	0.99
R4822:Dnhd1	UTSW	7	105,353,171 (GRCm39)	missense	probably benign	0.00
R4886:Dnhd1	UTSW	7	105,364,015 (GRCm39)	missense	probably benign	0.00
R4890:Dnhd1	UTSW	7	105,306,164 (GRCm39)	missense	possibly damaging	0.47
R4973:Dnhd1	UTSW	7	105,362,840 (GRCm39)	missense	probably benign	0.24
R5007:Dnhd1	UTSW	7	105,362,283 (GRCm39)	missense	probably damaging	1.00
R5048:Dnhd1	UTSW	7	105,342,904 (GRCm39)	missense	probably benign	0.01
R5151:Dnhd1	UTSW	7	105,362,647 (GRCm39)	missense	probably benign	0.22
R5179:Dnhd1	UTSW	7	105,363,759 (GRCm39)	missense	probably damaging	1.00
R5182:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5183:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5185:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5209:Dnhd1	UTSW	7	105,345,667 (GRCm39)	missense	probably benign	0.00
R5225:Dnhd1	UTSW	7	105,353,130 (GRCm39)	missense	possibly damaging	0.73
R5250:Dnhd1	UTSW	7	105,334,968 (GRCm39)	missense	probably damaging	1.00
R5257:Dnhd1	UTSW	7	105,323,244 (GRCm39)	missense	probably benign
R5258:Dnhd1	UTSW	7	105,323,244 (GRCm39)	missense	probably benign
R5273:Dnhd1	UTSW	7	105,363,689 (GRCm39)	missense	probably damaging	0.99
R5288:Dnhd1	UTSW	7	105,363,644 (GRCm39)	missense	possibly damaging	0.94
R5396:Dnhd1	UTSW	7	105,362,891 (GRCm39)	missense	probably benign	0.00
R5453:Dnhd1	UTSW	7	105,359,330 (GRCm39)	missense	probably damaging	1.00
R5511:Dnhd1	UTSW	7	105,363,363 (GRCm39)	missense	probably damaging	1.00
R5518:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5523:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5528:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5529:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5561:Dnhd1	UTSW	7	105,364,028 (GRCm39)	missense	probably damaging	0.99
R5681:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5682:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5683:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5684:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5686:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5697:Dnhd1	UTSW	7	105,323,395 (GRCm39)	missense	probably damaging	1.00
R5789:Dnhd1	UTSW	7	105,354,217 (GRCm39)	missense	possibly damaging	0.50
R5790:Dnhd1	UTSW	7	105,304,981 (GRCm39)	missense	probably damaging	1.00
R5814:Dnhd1	UTSW	7	105,369,102 (GRCm39)	missense	possibly damaging	0.69
R5828:Dnhd1	UTSW	7	105,369,388 (GRCm39)	missense	probably benign	0.00
R5852:Dnhd1	UTSW	7	105,344,955 (GRCm39)	missense	probably damaging	1.00
R5883:Dnhd1	UTSW	7	105,369,711 (GRCm39)	missense	probably damaging	0.98
R6115:Dnhd1	UTSW	7	105,363,194 (GRCm39)	missense	probably benign	0.00
R6119:Dnhd1	UTSW	7	105,358,647 (GRCm39)	missense	probably benign	0.18
R6212:Dnhd1	UTSW	7	105,353,255 (GRCm39)	missense	probably damaging	1.00
R6243:Dnhd1	UTSW	7	105,301,216 (GRCm39)	missense	probably damaging	1.00
R6265:Dnhd1	UTSW	7	105,342,577 (GRCm39)	missense	probably benign	0.07
R6332:Dnhd1	UTSW	7	105,343,273 (GRCm39)	missense	probably benign	0.02
R6344:Dnhd1	UTSW	7	105,343,817 (GRCm39)	missense	probably benign	0.38
R6477:Dnhd1	UTSW	7	105,327,093 (GRCm39)	missense	probably benign	0.05
R6642:Dnhd1	UTSW	7	105,353,006 (GRCm39)	missense	probably benign
R6663:Dnhd1	UTSW	7	105,334,899 (GRCm39)	splice site	probably null
R6730:Dnhd1	UTSW	7	105,353,082 (GRCm39)	missense	probably benign	0.00
R6748:Dnhd1	UTSW	7	105,369,844 (GRCm39)	missense	probably benign	0.03
R6833:Dnhd1	UTSW	7	105,352,580 (GRCm39)	missense	probably benign	0.01
R6850:Dnhd1	UTSW	7	105,369,137 (GRCm39)	missense	possibly damaging	0.68
R6853:Dnhd1	UTSW	7	105,352,935 (GRCm39)	missense	probably benign
R6860:Dnhd1	UTSW	7	105,327,473 (GRCm39)	missense	probably benign
R6898:Dnhd1	UTSW	7	105,336,584 (GRCm39)	missense	probably damaging	0.99
R6927:Dnhd1	UTSW	7	105,364,770 (GRCm39)	missense	probably damaging	1.00
R6952:Dnhd1	UTSW	7	105,362,895 (GRCm39)	missense	probably damaging	1.00
R6987:Dnhd1	UTSW	7	105,353,792 (GRCm39)	missense	probably damaging	0.98
R6988:Dnhd1	UTSW	7	105,363,417 (GRCm39)	missense	probably damaging	1.00
R7022:Dnhd1	UTSW	7	105,370,005 (GRCm39)	missense	probably benign	0.36
R7053:Dnhd1	UTSW	7	105,344,161 (GRCm39)	missense	probably damaging	1.00
R7085:Dnhd1	UTSW	7	105,364,468 (GRCm39)	missense	probably benign	0.26
R7086:Dnhd1	UTSW	7	105,357,739 (GRCm39)	missense	probably benign	0.03
R7112:Dnhd1	UTSW	7	105,363,192 (GRCm39)	missense	probably damaging	1.00
R7140:Dnhd1	UTSW	7	105,342,973 (GRCm39)	missense	probably benign	0.00
R7151:Dnhd1	UTSW	7	105,359,234 (GRCm39)	missense	probably benign	0.03
R7178:Dnhd1	UTSW	7	105,344,200 (GRCm39)	missense	probably damaging	0.98
R7345:Dnhd1	UTSW	7	105,353,174 (GRCm39)	missense	probably benign	0.17
R7349:Dnhd1	UTSW	7	105,359,330 (GRCm39)	missense	probably damaging	1.00
R7397:Dnhd1	UTSW	7	105,354,504 (GRCm39)	missense	possibly damaging	0.87
R7520:Dnhd1	UTSW	7	105,345,255 (GRCm39)	missense	probably benign	0.07
R7536:Dnhd1	UTSW	7	105,358,768 (GRCm39)	missense	probably damaging	1.00
R7539:Dnhd1	UTSW	7	105,370,119 (GRCm39)	missense	probably damaging	1.00
R7541:Dnhd1	UTSW	7	105,327,516 (GRCm39)	missense	probably damaging	1.00
R7619:Dnhd1	UTSW	7	105,323,475 (GRCm39)	missense	probably benign	0.01
R7676:Dnhd1	UTSW	7	105,333,294 (GRCm39)	missense	probably benign	0.09
R7689:Dnhd1	UTSW	7	105,363,170 (GRCm39)	missense	probably benign	0.07
R7712:Dnhd1	UTSW	7	105,300,831 (GRCm39)	missense	probably benign	0.17
R7729:Dnhd1	UTSW	7	105,354,472 (GRCm39)	missense	probably damaging	1.00
R7767:Dnhd1	UTSW	7	105,343,817 (GRCm39)	missense	probably benign	0.38
R7768:Dnhd1	UTSW	7	105,370,302 (GRCm39)	missense	possibly damaging	0.87
R7779:Dnhd1	UTSW	7	105,327,122 (GRCm39)	missense	probably benign	0.01
R7879:Dnhd1	UTSW	7	105,352,646 (GRCm39)	missense	probably benign	0.09
R7922:Dnhd1	UTSW	7	105,317,721 (GRCm39)	missense	probably damaging	1.00
R7951:Dnhd1	UTSW	7	105,327,211 (GRCm39)	missense	probably damaging	1.00
R8259:Dnhd1	UTSW	7	105,343,995 (GRCm39)	missense	probably benign	0.38
R8350:Dnhd1	UTSW	7	105,327,231 (GRCm39)	missense	probably damaging	0.99
R8380:Dnhd1	UTSW	7	105,327,073 (GRCm39)	missense	probably benign	0.31
R8392:Dnhd1	UTSW	7	105,352,550 (GRCm39)	missense	possibly damaging	0.84
R8478:Dnhd1	UTSW	7	105,332,001 (GRCm39)	missense	probably benign	0.00
R8708:Dnhd1	UTSW	7	105,343,487 (GRCm39)	nonsense	probably null
R8767:Dnhd1	UTSW	7	105,301,330 (GRCm39)	missense	probably damaging	1.00
R8825:Dnhd1	UTSW	7	105,343,174 (GRCm39)	missense	possibly damaging	0.95
R8849:Dnhd1	UTSW	7	105,370,723 (GRCm39)	missense	probably benign	0.00
R8903:Dnhd1	UTSW	7	105,362,855 (GRCm39)	nonsense	probably null
R8910:Dnhd1	UTSW	7	105,332,904 (GRCm39)	missense	possibly damaging	0.92
R8940:Dnhd1	UTSW	7	105,363,854 (GRCm39)	intron	probably benign
R8954:Dnhd1	UTSW	7	105,343,986 (GRCm39)	missense	probably benign	0.35
R8956:Dnhd1	UTSW	7	105,341,852 (GRCm39)	missense	probably damaging	0.99
R8971:Dnhd1	UTSW	7	105,358,528 (GRCm39)	nonsense	probably null
R8996:Dnhd1	UTSW	7	105,323,242 (GRCm39)	missense	probably damaging	1.00
R9051:Dnhd1	UTSW	7	105,341,933 (GRCm39)	missense	possibly damaging	0.54
R9058:Dnhd1	UTSW	7	105,333,270 (GRCm39)	missense	probably benign	0.01
R9109:Dnhd1	UTSW	7	105,333,173 (GRCm39)	missense	probably damaging	0.98
R9284:Dnhd1	UTSW	7	105,301,091 (GRCm39)	missense	probably damaging	1.00
R9295:Dnhd1	UTSW	7	105,363,348 (GRCm39)	missense	probably benign
R9298:Dnhd1	UTSW	7	105,333,173 (GRCm39)	missense	probably damaging	0.98
R9299:Dnhd1	UTSW	7	105,369,806 (GRCm39)	missense	probably benign	0.00
R9308:Dnhd1	UTSW	7	105,353,484 (GRCm39)	missense	probably damaging	1.00
R9337:Dnhd1	UTSW	7	105,369,806 (GRCm39)	missense	probably benign	0.00
R9385:Dnhd1	UTSW	7	105,361,972 (GRCm39)	missense	probably damaging	1.00
R9463:Dnhd1	UTSW	7	105,344,223 (GRCm39)	missense	probably benign
R9463:Dnhd1	UTSW	7	105,306,454 (GRCm39)	missense	probably benign	0.00
R9476:Dnhd1	UTSW	7	105,352,889 (GRCm39)	missense	possibly damaging	0.74
R9489:Dnhd1	UTSW	7	105,300,804 (GRCm39)	missense	probably benign
R9500:Dnhd1	UTSW	7	105,353,709 (GRCm39)	missense	probably benign
R9510:Dnhd1	UTSW	7	105,352,889 (GRCm39)	missense	possibly damaging	0.74
R9513:Dnhd1	UTSW	7	105,354,179 (GRCm39)	missense	probably damaging	1.00
R9537:Dnhd1	UTSW	7	105,344,740 (GRCm39)	missense	probably damaging	0.99
R9567:Dnhd1	UTSW	7	105,353,473 (GRCm39)	missense	probably benign	0.03
R9622:Dnhd1	UTSW	7	105,353,342 (GRCm39)	missense	probably benign
R9623:Dnhd1	UTSW	7	105,344,134 (GRCm39)	missense	probably damaging	1.00
R9623:Dnhd1	UTSW	7	105,335,773 (GRCm39)	missense	probably damaging	1.00
R9674:Dnhd1	UTSW	7	105,363,429 (GRCm39)	missense	probably damaging	1.00
R9756:Dnhd1	UTSW	7	105,353,135 (GRCm39)	missense	probably benign	0.19
R9777:Dnhd1	UTSW	7	105,369,456 (GRCm39)	missense	probably benign	0.14
R9778:Dnhd1	UTSW	7	105,353,240 (GRCm39)	missense	probably benign
R9781:Dnhd1	UTSW	7	105,352,917 (GRCm39)	missense	probably benign	0.31
R9796:Dnhd1	UTSW	7	105,342,537 (GRCm39)	missense	probably damaging	1.00
Z1088:Dnhd1	UTSW	7	105,361,934 (GRCm39)	missense	probably benign	0.00
Z1176:Dnhd1	UTSW	7	105,352,243 (GRCm39)	critical splice acceptor site	probably null
Z1176:Dnhd1	UTSW	7	105,327,506 (GRCm39)	missense	probably benign
Z1176:Dnhd1	UTSW	7	105,317,754 (GRCm39)	missense	probably damaging	0.98
Z1176:Dnhd1	UTSW	7	105,352,787 (GRCm39)	frame shift	probably null
Z1177:Dnhd1	UTSW	7	105,332,048 (GRCm39)	missense	possibly damaging	0.90

Predicted Primers

PCR Primer
(F):5'- CTTCAGGCTTTGCTAACCAACAAC -3'
(R):5'- CCGACAGGTGAAATATGCGC -3'

Sequencing Primer
(F):5'- AACCGTATTCGCTCAGGC -3'
(R):5'- CAGGTGAAATATGCGCTCTGG -3'

Posted On

2019-09-13