Incidental Mutation 'R7336:Nckap5'
| ID |
569465 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nckap5
|
| Ensembl Gene |
ENSMUSG00000049690 |
| Gene Name |
NCK-associated protein 5 |
| Synonyms |
LOC380609, D130011D22Rik, E030049G20Rik |
| MMRRC Submission |
045426-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7336 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
125841373-126758529 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 125953786 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Lysine
at position 922
(I922K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125624
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000057846]
[ENSMUST00000094609]
[ENSMUST00000094610]
[ENSMUST00000112583]
[ENSMUST00000161954]
[ENSMUST00000162877]
|
| AlphaFold |
E9QAE1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000057846
AA Change: I858K
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000062229
Gene: ENSMUSG00000049690
AA Change: I858K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
321 |
332 |
N/A |
INTRINSIC |
|
low complexity region
|
755 |
771 |
N/A |
INTRINSIC |
|
low complexity region
|
950 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
1070 |
1085 |
N/A |
INTRINSIC |
|
low complexity region
|
1181 |
1200 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1298 |
1602 |
1.8e-120 |
PFAM |
|
low complexity region
|
1728 |
1742 |
N/A |
INTRINSIC |
|
low complexity region
|
1757 |
1771 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094609
|
| SMART Domains |
Protein: ENSMUSP00000092192
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
113 |
364 |
3.6e-36 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094610
|
| SMART Domains |
Protein: ENSMUSP00000092193
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
1 |
101 |
8.8e-42 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112583
AA Change: I990K
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000108202
Gene: ENSMUSG00000049690
AA Change: I990K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
coiled coil region
|
176 |
254 |
N/A |
INTRINSIC |
|
low complexity region
|
301 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
453 |
464 |
N/A |
INTRINSIC |
|
low complexity region
|
887 |
903 |
N/A |
INTRINSIC |
|
low complexity region
|
1082 |
1103 |
N/A |
INTRINSIC |
|
low complexity region
|
1202 |
1217 |
N/A |
INTRINSIC |
|
low complexity region
|
1313 |
1332 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1431 |
1733 |
5.3e-119 |
PFAM |
|
low complexity region
|
1860 |
1874 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1903 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000161954
AA Change: I922K
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000125624
Gene: ENSMUSG00000049690
AA Change: I922K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
233 |
256 |
N/A |
INTRINSIC |
|
low complexity region
|
385 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
1014 |
1035 |
N/A |
INTRINSIC |
|
low complexity region
|
1134 |
1149 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1264 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1362 |
1666 |
2.1e-120 |
PFAM |
|
low complexity region
|
1792 |
1806 |
N/A |
INTRINSIC |
|
low complexity region
|
1821 |
1835 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162877
|
| SMART Domains |
Protein: ENSMUSP00000124748
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
9 |
296 |
6e-36 |
PFAM |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
99% (80/81) |
| Allele List at MGI |
All alleles(1) : Gene trapped(1) |
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl2fm1 |
G |
A |
3: 59,840,174 (GRCm39) |
|
probably null |
Het |
| Abca15 |
A |
T |
7: 119,987,456 (GRCm39) |
Q1247H |
possibly damaging |
Het |
| Acsf2 |
G |
C |
11: 94,462,476 (GRCm39) |
Q180E |
probably benign |
Het |
| Adamts8 |
A |
G |
9: 30,873,363 (GRCm39) |
D856G |
probably benign |
Het |
| Agrn |
A |
T |
4: 156,259,371 (GRCm39) |
C828* |
probably null |
Het |
| Ankub1 |
T |
C |
3: 57,573,108 (GRCm39) |
T205A |
probably benign |
Het |
| Atm |
A |
T |
9: 53,373,803 (GRCm39) |
Y2150N |
possibly damaging |
Het |
| Barhl1 |
A |
G |
2: 28,799,855 (GRCm39) |
F257L |
probably benign |
Het |
| Bcat2 |
T |
A |
7: 45,224,909 (GRCm39) |
C27S |
probably benign |
Het |
| Bod1l |
G |
A |
5: 41,978,867 (GRCm39) |
R816C |
probably damaging |
Het |
| Btg3 |
A |
G |
16: 78,161,695 (GRCm39) |
Y172H |
probably benign |
Het |
| Cacna1d |
T |
C |
14: 29,767,239 (GRCm39) |
D1940G |
probably benign |
Het |
| Catsperg2 |
T |
A |
7: 29,406,026 (GRCm39) |
N624I |
possibly damaging |
Het |
| Ccdc146 |
A |
G |
5: 21,508,110 (GRCm39) |
V646A |
probably benign |
Het |
| Ccp110 |
C |
T |
7: 118,321,433 (GRCm39) |
P363S |
probably damaging |
Het |
| Cct4 |
C |
A |
11: 22,951,564 (GRCm39) |
T377K |
possibly damaging |
Het |
| Cemip2 |
C |
A |
19: 21,803,509 (GRCm39) |
Y847* |
probably null |
Het |
| Cep350 |
T |
A |
1: 155,738,022 (GRCm39) |
H2607L |
probably benign |
Het |
| Cfap46 |
A |
G |
7: 139,200,020 (GRCm39) |
F1954L |
unknown |
Het |
| Chat |
C |
T |
14: 32,145,213 (GRCm39) |
|
probably null |
Het |
| Clasp2 |
A |
G |
9: 113,705,421 (GRCm39) |
|
probably null |
Het |
| Cldn9 |
T |
C |
17: 23,901,989 (GRCm39) |
D212G |
probably benign |
Het |
| Cp |
G |
A |
3: 20,018,696 (GRCm39) |
|
probably null |
Het |
| Cyfip1 |
T |
A |
7: 55,576,148 (GRCm39) |
I1108N |
possibly damaging |
Het |
| Dnah14 |
A |
G |
1: 181,625,299 (GRCm39) |
D4060G |
probably damaging |
Het |
| Dpyd |
A |
G |
3: 118,858,570 (GRCm39) |
T595A |
probably damaging |
Het |
| Eps8 |
G |
A |
6: 137,486,211 (GRCm39) |
R434C |
possibly damaging |
Het |
| Fasl |
A |
G |
1: 161,615,557 (GRCm39) |
Y100H |
probably damaging |
Het |
| Fkbp9 |
A |
T |
6: 56,826,712 (GRCm39) |
N104I |
probably damaging |
Het |
| Frmd4a |
A |
G |
2: 4,478,025 (GRCm39) |
T65A |
possibly damaging |
Het |
| Gm1110 |
T |
C |
9: 26,825,653 (GRCm39) |
N102S |
probably damaging |
Het |
| Gm2381 |
T |
C |
7: 42,471,804 (GRCm39) |
Q25R |
possibly damaging |
Het |
| Gtpbp2 |
A |
G |
17: 46,472,239 (GRCm39) |
Y58C |
probably damaging |
Het |
| H2-T3 |
C |
A |
17: 36,498,237 (GRCm39) |
K269N |
probably damaging |
Het |
| Icosl |
C |
A |
10: 77,909,707 (GRCm39) |
Y217* |
probably null |
Het |
| Il17rd |
G |
T |
14: 26,809,503 (GRCm39) |
R153L |
probably benign |
Het |
| Kif17 |
C |
A |
4: 138,025,617 (GRCm39) |
T973K |
possibly damaging |
Het |
| Klk1b16 |
A |
G |
7: 43,790,907 (GRCm39) |
I236M |
probably benign |
Het |
| Lgmn |
G |
A |
12: 102,389,998 (GRCm39) |
|
probably benign |
Het |
| Lmbr1l |
T |
C |
15: 98,811,468 (GRCm39) |
D54G |
possibly damaging |
Het |
| Lrrc49 |
A |
T |
9: 60,584,474 (GRCm39) |
I196N |
possibly damaging |
Het |
| Maml1 |
C |
T |
11: 50,157,276 (GRCm39) |
A300T |
possibly damaging |
Het |
| Mapkap1 |
A |
T |
2: 34,423,829 (GRCm39) |
Q293L |
possibly damaging |
Het |
| Mki67 |
T |
C |
7: 135,315,568 (GRCm39) |
T69A |
probably benign |
Het |
| Mlph |
G |
A |
1: 90,849,705 (GRCm39) |
|
probably null |
Het |
| Myh1 |
A |
T |
11: 67,111,435 (GRCm39) |
M1625L |
probably benign |
Het |
| Myh3 |
G |
T |
11: 66,981,847 (GRCm39) |
R781L |
probably benign |
Het |
| Nlrp5 |
T |
A |
7: 23,117,059 (GRCm39) |
M261K |
probably damaging |
Het |
| Or1e1d-ps1 |
G |
A |
11: 73,819,663 (GRCm39) |
M204I |
probably benign |
Het |
| Or4f47 |
A |
T |
2: 111,972,514 (GRCm39) |
S75C |
possibly damaging |
Het |
| Or5af1 |
T |
A |
11: 58,722,750 (GRCm39) |
Y257N |
probably damaging |
Het |
| Or8g52 |
A |
G |
9: 39,630,906 (GRCm39) |
N128D |
probably benign |
Het |
| Pak1 |
T |
A |
7: 97,538,179 (GRCm39) |
V262E |
probably benign |
Het |
| Pigw |
A |
T |
11: 84,767,930 (GRCm39) |
D466E |
probably damaging |
Het |
| Pira2 |
A |
T |
7: 3,847,344 (GRCm39) |
L115Q |
probably damaging |
Het |
| Rbm15 |
A |
C |
3: 107,240,432 (GRCm39) |
|
probably benign |
Het |
| Rfx1 |
A |
G |
8: 84,800,385 (GRCm39) |
|
probably benign |
Het |
| Rfx7 |
A |
G |
9: 72,500,639 (GRCm39) |
Y133C |
probably damaging |
Het |
| Serpinb9d |
T |
A |
13: 33,384,702 (GRCm39) |
D226E |
probably benign |
Het |
| Sgk3 |
G |
A |
1: 9,954,701 (GRCm39) |
A271T |
possibly damaging |
Het |
| Sh2d5 |
T |
A |
4: 137,984,150 (GRCm39) |
C173S |
probably benign |
Het |
| Skint8 |
T |
C |
4: 111,796,769 (GRCm39) |
V291A |
probably benign |
Het |
| Slc22a27 |
T |
A |
19: 7,904,054 (GRCm39) |
N28Y |
probably benign |
Het |
| Slc25a54 |
G |
A |
3: 109,023,751 (GRCm39) |
V449I |
probably benign |
Het |
| Slc39a9 |
T |
C |
12: 80,726,316 (GRCm39) |
F255S |
probably damaging |
Het |
| Spata31d1c |
C |
T |
13: 65,183,942 (GRCm39) |
H495Y |
probably damaging |
Het |
| Stab2 |
G |
A |
10: 86,805,049 (GRCm39) |
Q310* |
probably null |
Het |
| Supt16 |
C |
A |
14: 52,408,948 (GRCm39) |
A809S |
possibly damaging |
Het |
| Tenm3 |
A |
T |
8: 48,689,212 (GRCm39) |
M2125K |
possibly damaging |
Het |
| Tex2 |
G |
A |
11: 106,439,685 (GRCm39) |
T565M |
unknown |
Het |
| Tll1 |
G |
A |
8: 64,478,176 (GRCm39) |
A859V |
probably damaging |
Het |
| Tmem106c |
C |
T |
15: 97,867,512 (GRCm39) |
T232I |
possibly damaging |
Het |
| Trim65 |
T |
G |
11: 116,019,116 (GRCm39) |
D141A |
probably benign |
Het |
| Trim80 |
T |
C |
11: 115,332,042 (GRCm39) |
F78S |
probably damaging |
Het |
| Txnrd1 |
T |
A |
10: 82,709,051 (GRCm39) |
I83N |
probably benign |
Het |
| Vnn3 |
G |
A |
10: 23,727,806 (GRCm39) |
G72D |
probably benign |
Het |
| Wasl |
G |
T |
6: 24,619,686 (GRCm39) |
P278Q |
unknown |
Het |
| Wdr62 |
A |
T |
7: 29,943,342 (GRCm39) |
L951Q |
probably damaging |
Het |
| Zfp760 |
C |
T |
17: 21,942,814 (GRCm39) |
T663I |
unknown |
Het |
|
| Other mutations in Nckap5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00833:Nckap5
|
APN |
1 |
125,954,889 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00956:Nckap5
|
APN |
1 |
125,952,755 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01414:Nckap5
|
APN |
1 |
126,456,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01482:Nckap5
|
APN |
1 |
125,950,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01508:Nckap5
|
APN |
1 |
125,953,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02071:Nckap5
|
APN |
1 |
125,909,305 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02129:Nckap5
|
APN |
1 |
125,955,432 (GRCm39) |
nonsense |
probably null |
|
|
IGL02821:Nckap5
|
APN |
1 |
125,955,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03174:Nckap5
|
APN |
1 |
125,909,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
F5493:Nckap5
|
UTSW |
1 |
125,953,564 (GRCm39) |
missense |
probably benign |
|
|
G5030:Nckap5
|
UTSW |
1 |
125,953,591 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0033:Nckap5
|
UTSW |
1 |
125,867,979 (GRCm39) |
intron |
probably benign |
|
|
R0164:Nckap5
|
UTSW |
1 |
125,952,144 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0164:Nckap5
|
UTSW |
1 |
125,952,144 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0349:Nckap5
|
UTSW |
1 |
125,954,171 (GRCm39) |
missense |
probably benign |
|
|
R0482:Nckap5
|
UTSW |
1 |
125,954,102 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0508:Nckap5
|
UTSW |
1 |
125,909,121 (GRCm39) |
splice site |
probably null |
|
|
R0541:Nckap5
|
UTSW |
1 |
126,623,459 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0609:Nckap5
|
UTSW |
1 |
125,955,025 (GRCm39) |
nonsense |
probably null |
|
|
R0701:Nckap5
|
UTSW |
1 |
125,953,094 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0782:Nckap5
|
UTSW |
1 |
125,909,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1389:Nckap5
|
UTSW |
1 |
125,954,447 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1401:Nckap5
|
UTSW |
1 |
125,942,398 (GRCm39) |
splice site |
probably benign |
|
|
R1436:Nckap5
|
UTSW |
1 |
125,953,798 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1506:Nckap5
|
UTSW |
1 |
125,953,650 (GRCm39) |
nonsense |
probably null |
|
|
R1528:Nckap5
|
UTSW |
1 |
125,952,659 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1942:Nckap5
|
UTSW |
1 |
125,952,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1968:Nckap5
|
UTSW |
1 |
125,942,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2055:Nckap5
|
UTSW |
1 |
125,954,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2105:Nckap5
|
UTSW |
1 |
125,954,255 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2214:Nckap5
|
UTSW |
1 |
125,953,487 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R2311:Nckap5
|
UTSW |
1 |
126,456,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2403:Nckap5
|
UTSW |
1 |
125,955,146 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2430:Nckap5
|
UTSW |
1 |
125,842,494 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2914:Nckap5
|
UTSW |
1 |
125,954,274 (GRCm39) |
splice site |
probably null |
|
|
R3782:Nckap5
|
UTSW |
1 |
125,952,811 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4133:Nckap5
|
UTSW |
1 |
126,150,443 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4249:Nckap5
|
UTSW |
1 |
125,955,376 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4448:Nckap5
|
UTSW |
1 |
125,953,463 (GRCm39) |
nonsense |
probably null |
|
|
R4456:Nckap5
|
UTSW |
1 |
125,842,472 (GRCm39) |
unclassified |
probably benign |
|
|
R4682:Nckap5
|
UTSW |
1 |
126,030,279 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4817:Nckap5
|
UTSW |
1 |
125,954,952 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4907:Nckap5
|
UTSW |
1 |
125,953,889 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4908:Nckap5
|
UTSW |
1 |
125,955,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Nckap5
|
UTSW |
1 |
125,954,765 (GRCm39) |
nonsense |
probably null |
|
|
R4926:Nckap5
|
UTSW |
1 |
126,456,378 (GRCm39) |
intron |
probably benign |
|
|
R5032:Nckap5
|
UTSW |
1 |
125,904,786 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R5133:Nckap5
|
UTSW |
1 |
125,961,697 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5197:Nckap5
|
UTSW |
1 |
126,150,410 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5238:Nckap5
|
UTSW |
1 |
125,955,461 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5257:Nckap5
|
UTSW |
1 |
125,952,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5277:Nckap5
|
UTSW |
1 |
125,954,277 (GRCm39) |
nonsense |
probably null |
|
|
R5512:Nckap5
|
UTSW |
1 |
125,955,481 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5700:Nckap5
|
UTSW |
1 |
125,904,662 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5789:Nckap5
|
UTSW |
1 |
125,955,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6029:Nckap5
|
UTSW |
1 |
125,953,523 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6249:Nckap5
|
UTSW |
1 |
125,952,667 (GRCm39) |
missense |
probably benign |
|
|
R6292:Nckap5
|
UTSW |
1 |
125,842,752 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6521:Nckap5
|
UTSW |
1 |
126,309,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Nckap5
|
UTSW |
1 |
125,950,931 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7017:Nckap5
|
UTSW |
1 |
126,030,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7018:Nckap5
|
UTSW |
1 |
125,952,785 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7054:Nckap5
|
UTSW |
1 |
126,186,449 (GRCm39) |
splice site |
probably null |
|
|
R7204:Nckap5
|
UTSW |
1 |
125,954,104 (GRCm39) |
missense |
probably benign |
|
|
R7544:Nckap5
|
UTSW |
1 |
125,953,948 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7590:Nckap5
|
UTSW |
1 |
125,954,270 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7684:Nckap5
|
UTSW |
1 |
125,954,594 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7749:Nckap5
|
UTSW |
1 |
125,952,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7773:Nckap5
|
UTSW |
1 |
125,954,581 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7813:Nckap5
|
UTSW |
1 |
125,953,163 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7970:Nckap5
|
UTSW |
1 |
125,952,758 (GRCm39) |
nonsense |
probably null |
|
|
R7992:Nckap5
|
UTSW |
1 |
125,954,547 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8278:Nckap5
|
UTSW |
1 |
125,955,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8373:Nckap5
|
UTSW |
1 |
125,954,032 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8414:Nckap5
|
UTSW |
1 |
125,942,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8755:Nckap5
|
UTSW |
1 |
125,954,279 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8845:Nckap5
|
UTSW |
1 |
125,909,423 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9016:Nckap5
|
UTSW |
1 |
126,623,491 (GRCm39) |
start codon destroyed |
probably null |
0.01 |
|
R9209:Nckap5
|
UTSW |
1 |
125,867,928 (GRCm39) |
missense |
unknown |
|
|
R9214:Nckap5
|
UTSW |
1 |
125,942,376 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9300:Nckap5
|
UTSW |
1 |
125,909,423 (GRCm39) |
nonsense |
probably null |
|
|
R9464:Nckap5
|
UTSW |
1 |
125,952,494 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9572:Nckap5
|
UTSW |
1 |
125,955,454 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9721:Nckap5
|
UTSW |
1 |
125,955,017 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9748:Nckap5
|
UTSW |
1 |
125,953,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Nckap5
|
UTSW |
1 |
125,952,569 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
Z1176:Nckap5
|
UTSW |
1 |
126,456,418 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Nckap5
|
UTSW |
1 |
126,150,396 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCACTCCTGAGAAGGAAGGC -3'
(R):5'- TAAGTCCAGGGTTGAAATCCC -3'
Sequencing Primer
(F):5'- GACAGGCTTTTACAAGATGTCACCTC -3'
(R):5'- GTTGAAATCCCCGCTGTTGAAAG -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation