Incidental Mutation 'R7340:Tnn'
| ID |
569740 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnn
|
| Ensembl Gene |
ENSMUSG00000026725 |
| Gene Name |
tenascin N |
| Synonyms |
tenascin-W, Tnw |
| MMRRC Submission |
045430-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.396)
|
| Stock # |
R7340 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
159912599-159981150 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 159973592 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 258
(D258E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000039452
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039178]
[ENSMUST00000131919]
|
| AlphaFold |
Q80Z71 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000039178
AA Change: D258E
PolyPhen 2
Score 0.977 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000039452
Gene: ENSMUSG00000026725
AA Change: D258E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
100 |
132 |
N/A |
INTRINSIC |
|
EGF_like
|
170 |
198 |
3.5e1 |
SMART |
|
EGF
|
201 |
229 |
2.29e1 |
SMART |
|
EGF_like
|
232 |
260 |
2.86e1 |
SMART |
|
FN3
|
262 |
341 |
1.81e-8 |
SMART |
|
FN3
|
351 |
432 |
1.08e-6 |
SMART |
|
FN3
|
443 |
521 |
1.19e-8 |
SMART |
|
FN3
|
531 |
608 |
2.64e-10 |
SMART |
|
FN3
|
619 |
696 |
1.6e-9 |
SMART |
|
FN3
|
707 |
784 |
9.04e-9 |
SMART |
|
FN3
|
795 |
872 |
7.34e-9 |
SMART |
|
FN3
|
883 |
960 |
9.04e-9 |
SMART |
|
FN3
|
971 |
1048 |
1.07e-10 |
SMART |
|
FN3
|
1059 |
1136 |
7.57e-11 |
SMART |
|
FN3
|
1147 |
1224 |
4.59e-10 |
SMART |
|
FN3
|
1235 |
1312 |
1.95e-4 |
SMART |
|
FBG
|
1327 |
1539 |
1.16e-114 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000131919
AA Change: D258E
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000115685
Gene: ENSMUSG00000026725
AA Change: D258E
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
100 |
132 |
N/A |
INTRINSIC |
|
EGF_like
|
170 |
198 |
3.5e1 |
SMART |
|
EGF
|
201 |
229 |
2.29e1 |
SMART |
|
EGF_like
|
232 |
260 |
2.86e1 |
SMART |
|
FN3
|
262 |
341 |
1.81e-8 |
SMART |
|
FN3
|
351 |
432 |
1.08e-6 |
SMART |
|
FN3
|
443 |
521 |
1.19e-8 |
SMART |
|
FN3
|
531 |
608 |
2.64e-10 |
SMART |
|
FN3
|
619 |
696 |
1.6e-9 |
SMART |
|
FN3
|
707 |
784 |
9.04e-9 |
SMART |
|
FN3
|
795 |
872 |
7.57e-11 |
SMART |
|
FN3
|
883 |
960 |
4.59e-10 |
SMART |
|
FN3
|
971 |
1048 |
1.95e-4 |
SMART |
|
FBG
|
1063 |
1275 |
1.16e-114 |
SMART |
|
| Meta Mutation Damage Score |
0.5003 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
99% (83/84) |
| Allele List at MGI |
All alleles(2) : Targeted, other(2)
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb11 |
C |
T |
2: 69,130,211 (GRCm39) |
D282N |
probably damaging |
Het |
| Adam30 |
A |
T |
3: 98,069,637 (GRCm39) |
N490I |
probably benign |
Het |
| Ankrd55 |
A |
T |
13: 112,492,497 (GRCm39) |
I223F |
probably damaging |
Het |
| Ano8 |
T |
A |
8: 71,935,655 (GRCm39) |
E321V |
probably damaging |
Het |
| Apc2 |
A |
G |
10: 80,149,316 (GRCm39) |
K1457E |
probably benign |
Het |
| Asb15 |
T |
A |
6: 24,558,513 (GRCm39) |
V38E |
probably benign |
Het |
| Atp4a |
T |
C |
7: 30,416,155 (GRCm39) |
S417P |
possibly damaging |
Het |
| AY358078 |
A |
G |
14: 52,063,716 (GRCm39) |
N454S |
probably damaging |
Het |
| Cables2 |
A |
G |
2: 179,903,450 (GRCm39) |
Y245H |
|
Het |
| Cactin |
CCGGAGTCGGAGTCGGAGTCGGAGTCGGAGTCGGAG |
CCGGAGTCGGAGTCGGAGTCGGAGTCGGAGTCGGAGTCGGAG |
10: 81,157,152 (GRCm39) |
|
probably benign |
Het |
| Camsap3 |
G |
A |
8: 3,637,960 (GRCm39) |
|
probably null |
Het |
| Ccdc178 |
A |
T |
18: 22,150,518 (GRCm39) |
V705E |
probably benign |
Het |
| Ccdc47 |
T |
C |
11: 106,091,799 (GRCm39) |
Q472R |
possibly damaging |
Het |
| Ccdc62 |
A |
G |
5: 124,089,283 (GRCm39) |
D307G |
probably damaging |
Het |
| Cdcp3 |
A |
G |
7: 130,879,344 (GRCm39) |
T1788A |
unknown |
Het |
| Cdh23 |
A |
G |
10: 60,366,775 (GRCm39) |
I235T |
probably benign |
Het |
| Cep89 |
G |
A |
7: 35,129,353 (GRCm39) |
R630H |
probably damaging |
Het |
| Cfap65 |
T |
C |
1: 74,960,742 (GRCm39) |
N743D |
probably benign |
Het |
| Cimap1b |
T |
A |
15: 89,262,610 (GRCm39) |
T116S |
probably benign |
Het |
| Clec16a |
A |
G |
16: 10,398,827 (GRCm39) |
N329S |
probably null |
Het |
| Col25a1 |
A |
G |
3: 130,340,006 (GRCm39) |
|
probably null |
Het |
| Daam1 |
T |
G |
12: 72,035,713 (GRCm39) |
D969E |
probably benign |
Het |
| Dntt |
A |
C |
19: 41,047,004 (GRCm39) |
|
probably null |
Het |
| Dsel |
C |
T |
1: 111,789,303 (GRCm39) |
G411S |
probably damaging |
Het |
| Dst |
T |
A |
1: 34,229,810 (GRCm39) |
Y2468N |
probably benign |
Het |
| Exosc9 |
A |
G |
3: 36,615,297 (GRCm39) |
T262A |
possibly damaging |
Het |
| Exph5 |
G |
A |
9: 53,288,309 (GRCm39) |
A1797T |
probably damaging |
Het |
| Fbp2 |
A |
T |
13: 62,985,061 (GRCm39) |
Y287N |
probably damaging |
Het |
| Fmn2 |
CCCTCCTCTCCCTGGAATGGGAATACCTCCCCCACCTCCTCTCCCTGGAATGGGAATACCTCCCCCACCTCCTCTCCCTGGAATGGGAATATCTCCCCTACCTCCTCTCCCTGGAATGGGAATACCTCC |
CCCTCCTCTCCCTGGAATGGGAATACCTCCCCCACCTCCTCTCCCTGGAATGGGAATATCTCCCCTACCTCCTCTCCCTGGAATGGGAATACCTCC |
1: 174,436,769 (GRCm39) |
|
probably benign |
Het |
| Fus |
T |
A |
7: 127,581,123 (GRCm39) |
|
probably null |
Het |
| Galnt9 |
T |
A |
5: 110,762,054 (GRCm39) |
N397K |
probably damaging |
Het |
| Gdi1 |
G |
A |
X: 73,350,461 (GRCm39) |
R55H |
probably benign |
Het |
| Gga1 |
A |
G |
15: 78,775,651 (GRCm39) |
T369A |
probably benign |
Het |
| Gp1ba |
T |
C |
11: 70,531,119 (GRCm39) |
I295T |
unknown |
Het |
| Hk2 |
T |
C |
6: 82,705,873 (GRCm39) |
E810G |
probably benign |
Het |
| Igsf10 |
A |
G |
3: 59,233,189 (GRCm39) |
V1848A |
probably damaging |
Het |
| Insrr |
G |
A |
3: 87,721,623 (GRCm39) |
|
probably null |
Het |
| Ip6k3 |
T |
A |
17: 27,367,504 (GRCm39) |
M231L |
probably benign |
Het |
| Itgb8 |
T |
C |
12: 119,155,939 (GRCm39) |
N171S |
probably benign |
Het |
| Ldlrad3 |
T |
C |
2: 101,897,184 (GRCm39) |
|
probably null |
Het |
| Ltbp1 |
T |
A |
17: 75,634,223 (GRCm39) |
C886* |
probably null |
Het |
| Mettl13 |
T |
C |
1: 162,366,547 (GRCm39) |
D444G |
probably benign |
Het |
| Mns1 |
A |
G |
9: 72,356,025 (GRCm39) |
Y224C |
probably damaging |
Het |
| Mri1 |
C |
T |
8: 84,983,525 (GRCm39) |
R122Q |
probably benign |
Het |
| Ms4a6d |
G |
A |
19: 11,567,437 (GRCm39) |
Q155* |
probably null |
Het |
| Myo5c |
A |
C |
9: 75,196,423 (GRCm39) |
K1290Q |
probably benign |
Het |
| Nlrp12 |
T |
G |
7: 3,281,755 (GRCm39) |
Q842H |
possibly damaging |
Het |
| Oga |
G |
A |
19: 45,755,895 (GRCm39) |
Q583* |
probably null |
Het |
| Or14c44 |
T |
C |
7: 86,061,957 (GRCm39) |
L129P |
possibly damaging |
Het |
| Or14j8 |
T |
A |
17: 38,263,413 (GRCm39) |
R167S |
probably benign |
Het |
| Or2t1 |
A |
T |
14: 14,328,401 (GRCm38) |
T97S |
possibly damaging |
Het |
| Or5d39 |
T |
C |
2: 87,979,620 (GRCm39) |
T248A |
possibly damaging |
Het |
| Otoa |
A |
G |
7: 120,729,288 (GRCm39) |
T554A |
probably benign |
Het |
| Per1 |
A |
G |
11: 68,994,008 (GRCm39) |
D438G |
probably damaging |
Het |
| Phactr3 |
G |
A |
2: 177,975,854 (GRCm39) |
R533H |
probably damaging |
Het |
| Phykpl |
T |
C |
11: 51,490,370 (GRCm39) |
F417S |
probably damaging |
Het |
| Pole |
A |
T |
5: 110,482,330 (GRCm39) |
T2057S |
probably benign |
Het |
| Polq |
A |
G |
16: 36,881,288 (GRCm39) |
T1151A |
probably benign |
Het |
| Polr1g |
T |
C |
7: 19,093,073 (GRCm39) |
T36A |
probably benign |
Het |
| Rbm26 |
A |
T |
14: 105,389,976 (GRCm39) |
V216E |
possibly damaging |
Het |
| Ryk |
T |
C |
9: 102,775,737 (GRCm39) |
I449T |
probably damaging |
Het |
| Sap25 |
A |
G |
5: 137,640,935 (GRCm39) |
T225A |
probably benign |
Het |
| Sart3 |
A |
G |
5: 113,882,728 (GRCm39) |
M864T |
probably benign |
Het |
| Sec31b |
T |
C |
19: 44,517,161 (GRCm39) |
S280G |
probably benign |
Het |
| Sema4d |
A |
T |
13: 51,877,598 (GRCm39) |
I78N |
probably damaging |
Het |
| Sgip1 |
G |
C |
4: 102,778,661 (GRCm39) |
R419S |
unknown |
Het |
| Slc13a3 |
T |
C |
2: 165,272,210 (GRCm39) |
I278V |
probably benign |
Het |
| Slc2a5 |
A |
G |
4: 150,224,439 (GRCm39) |
D312G |
probably benign |
Het |
| Slc39a2 |
A |
T |
14: 52,131,660 (GRCm39) |
Q77L |
possibly damaging |
Het |
| Srbd1 |
A |
T |
17: 86,443,782 (GRCm39) |
V148E |
probably benign |
Het |
| Syngr2 |
A |
G |
11: 117,703,322 (GRCm39) |
E46G |
probably damaging |
Het |
| Taok1 |
A |
G |
11: 77,470,643 (GRCm39) |
V54A |
possibly damaging |
Het |
| Tas2r106 |
T |
A |
6: 131,655,185 (GRCm39) |
H222L |
probably damaging |
Het |
| Tcaf3 |
A |
G |
6: 42,566,848 (GRCm39) |
I747T |
probably benign |
Het |
| Tmem151b |
G |
T |
17: 45,856,195 (GRCm39) |
P415Q |
probably benign |
Het |
| Tmf1 |
T |
C |
6: 97,145,061 (GRCm39) |
D659G |
possibly damaging |
Het |
| Traj33 |
A |
G |
14: 54,422,862 (GRCm39) |
I16V |
unknown |
Het |
| Ttll13 |
G |
T |
7: 79,906,772 (GRCm39) |
C480F |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,714,415 (GRCm39) |
N8137S |
unknown |
Het |
| Vmn1r85 |
T |
C |
7: 12,819,073 (GRCm39) |
N24D |
probably damaging |
Het |
| Wdr81 |
T |
C |
11: 75,335,525 (GRCm39) |
Q649R |
probably null |
Het |
| Zan |
T |
C |
5: 137,382,092 (GRCm39) |
T5152A |
unknown |
Het |
| Zc3h6 |
A |
G |
2: 128,835,110 (GRCm39) |
D82G |
possibly damaging |
Het |
|
| Other mutations in Tnn |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00095:Tnn
|
APN |
1 |
159,953,021 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL00433:Tnn
|
APN |
1 |
159,925,776 (GRCm39) |
splice site |
probably benign |
|
|
IGL00858:Tnn
|
APN |
1 |
159,915,962 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00939:Tnn
|
APN |
1 |
159,975,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01569:Tnn
|
APN |
1 |
159,948,124 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01591:Tnn
|
APN |
1 |
159,953,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01628:Tnn
|
APN |
1 |
159,975,172 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL01811:Tnn
|
APN |
1 |
159,934,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01813:Tnn
|
APN |
1 |
159,916,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02340:Tnn
|
APN |
1 |
159,972,775 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02488:Tnn
|
APN |
1 |
159,968,163 (GRCm39) |
missense |
probably benign |
0.21 |
|
IGL02535:Tnn
|
APN |
1 |
159,950,222 (GRCm39) |
splice site |
probably null |
|
|
IGL02563:Tnn
|
APN |
1 |
159,942,123 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02572:Tnn
|
APN |
1 |
159,913,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02740:Tnn
|
APN |
1 |
159,968,347 (GRCm39) |
splice site |
probably benign |
|
|
IGL02818:Tnn
|
APN |
1 |
159,943,848 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03284:Tnn
|
APN |
1 |
159,953,022 (GRCm39) |
missense |
probably benign |
0.01 |
|
1mM(1):Tnn
|
UTSW |
1 |
159,924,911 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4305001:Tnn
|
UTSW |
1 |
159,913,647 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0023:Tnn
|
UTSW |
1 |
159,932,498 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0234:Tnn
|
UTSW |
1 |
159,916,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Tnn
|
UTSW |
1 |
159,916,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0316:Tnn
|
UTSW |
1 |
159,948,137 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0492:Tnn
|
UTSW |
1 |
159,948,327 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0547:Tnn
|
UTSW |
1 |
159,943,907 (GRCm39) |
intron |
probably benign |
|
|
R1067:Tnn
|
UTSW |
1 |
159,952,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1563:Tnn
|
UTSW |
1 |
159,952,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1565:Tnn
|
UTSW |
1 |
159,924,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1615:Tnn
|
UTSW |
1 |
159,945,978 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1637:Tnn
|
UTSW |
1 |
159,975,170 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1707:Tnn
|
UTSW |
1 |
159,972,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Tnn
|
UTSW |
1 |
159,975,154 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1797:Tnn
|
UTSW |
1 |
159,968,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1847:Tnn
|
UTSW |
1 |
159,943,752 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1925:Tnn
|
UTSW |
1 |
159,924,799 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2182:Tnn
|
UTSW |
1 |
159,968,170 (GRCm39) |
splice site |
probably null |
|
|
R2196:Tnn
|
UTSW |
1 |
159,924,798 (GRCm39) |
nonsense |
probably null |
|
|
R2225:Tnn
|
UTSW |
1 |
159,975,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2227:Tnn
|
UTSW |
1 |
159,975,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2286:Tnn
|
UTSW |
1 |
159,938,079 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R2850:Tnn
|
UTSW |
1 |
159,966,857 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3110:Tnn
|
UTSW |
1 |
159,943,856 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R3111:Tnn
|
UTSW |
1 |
159,934,625 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3112:Tnn
|
UTSW |
1 |
159,943,856 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R3729:Tnn
|
UTSW |
1 |
159,973,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4183:Tnn
|
UTSW |
1 |
159,924,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4439:Tnn
|
UTSW |
1 |
159,943,650 (GRCm39) |
missense |
probably benign |
|
|
R4441:Tnn
|
UTSW |
1 |
159,943,650 (GRCm39) |
missense |
probably benign |
|
|
R4588:Tnn
|
UTSW |
1 |
159,972,681 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4646:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4647:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4648:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4701:Tnn
|
UTSW |
1 |
159,975,338 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4703:Tnn
|
UTSW |
1 |
159,943,815 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4737:Tnn
|
UTSW |
1 |
159,973,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4801:Tnn
|
UTSW |
1 |
159,972,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4802:Tnn
|
UTSW |
1 |
159,972,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4868:Tnn
|
UTSW |
1 |
159,958,443 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4977:Tnn
|
UTSW |
1 |
159,948,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5011:Tnn
|
UTSW |
1 |
159,953,949 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5026:Tnn
|
UTSW |
1 |
159,973,707 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5027:Tnn
|
UTSW |
1 |
159,972,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5049:Tnn
|
UTSW |
1 |
159,968,308 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5119:Tnn
|
UTSW |
1 |
159,948,122 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5128:Tnn
|
UTSW |
1 |
159,950,464 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5234:Tnn
|
UTSW |
1 |
159,972,569 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5398:Tnn
|
UTSW |
1 |
159,975,092 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5424:Tnn
|
UTSW |
1 |
159,950,272 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5452:Tnn
|
UTSW |
1 |
159,937,831 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5466:Tnn
|
UTSW |
1 |
159,948,106 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6022:Tnn
|
UTSW |
1 |
159,937,928 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6062:Tnn
|
UTSW |
1 |
159,925,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6086:Tnn
|
UTSW |
1 |
159,913,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6132:Tnn
|
UTSW |
1 |
159,973,641 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6324:Tnn
|
UTSW |
1 |
159,972,774 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6455:Tnn
|
UTSW |
1 |
159,942,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6563:Tnn
|
UTSW |
1 |
159,915,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6650:Tnn
|
UTSW |
1 |
159,942,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6806:Tnn
|
UTSW |
1 |
159,948,278 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6810:Tnn
|
UTSW |
1 |
159,932,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7157:Tnn
|
UTSW |
1 |
159,953,947 (GRCm39) |
nonsense |
probably null |
|
|
R7243:Tnn
|
UTSW |
1 |
159,934,687 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7472:Tnn
|
UTSW |
1 |
159,937,917 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7502:Tnn
|
UTSW |
1 |
159,937,929 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7527:Tnn
|
UTSW |
1 |
159,946,074 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R7608:Tnn
|
UTSW |
1 |
159,915,984 (GRCm39) |
nonsense |
probably null |
|
|
R7746:Tnn
|
UTSW |
1 |
159,942,255 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8096:Tnn
|
UTSW |
1 |
159,950,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8136:Tnn
|
UTSW |
1 |
159,934,630 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8191:Tnn
|
UTSW |
1 |
159,953,088 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8334:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8335:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8337:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8338:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8427:Tnn
|
UTSW |
1 |
159,958,256 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8433:Tnn
|
UTSW |
1 |
159,924,790 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8479:Tnn
|
UTSW |
1 |
159,950,397 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8505:Tnn
|
UTSW |
1 |
159,973,593 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8554:Tnn
|
UTSW |
1 |
159,937,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8717:Tnn
|
UTSW |
1 |
159,943,846 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8850:Tnn
|
UTSW |
1 |
159,937,814 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8928:Tnn
|
UTSW |
1 |
159,953,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9209:Tnn
|
UTSW |
1 |
159,953,986 (GRCm39) |
missense |
probably benign |
0.02 |
|
X0019:Tnn
|
UTSW |
1 |
159,913,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tnn
|
UTSW |
1 |
159,973,863 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Tnn
|
UTSW |
1 |
159,954,097 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCATTCTATCAGAATCAGGACCA -3'
(R):5'- TGTGTGACGCGCCCTATGT -3'
Sequencing Primer
(F):5'- GCAGGAGACCCAGGACTTTATTC -3'
(R):5'- CCTATGTGGGGGTCGACTGC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation