Incidental Mutation 'R7348:Copa'
| ID |
570319 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Copa
|
| Ensembl Gene |
ENSMUSG00000026553 |
| Gene Name |
coatomer protein complex subunit alpha |
| Synonyms |
xenin |
| MMRRC Submission |
045380-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.971)
|
| Stock # |
R7348 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
171910096-171949897 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 171929790 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 286
(T286A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000118179
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000027833]
[ENSMUST00000124289]
[ENSMUST00000135192]
|
| AlphaFold |
Q8CIE6 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000027833
AA Change: T286A
PolyPhen 2
Score 0.978 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000027833
Gene: ENSMUSG00000026553
AA Change: T286A
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
2 |
37 |
2.86e0 |
SMART |
|
WD40
|
40 |
79 |
1.11e-6 |
SMART |
|
WD40
|
82 |
121 |
4.76e-6 |
SMART |
|
WD40
|
124 |
163 |
2.24e-11 |
SMART |
|
WD40
|
194 |
233 |
2.98e-7 |
SMART |
|
WD40
|
238 |
277 |
8.42e-7 |
SMART |
|
WD40
|
280 |
318 |
1.38e1 |
SMART |
|
Pfam:Coatomer_WDAD
|
338 |
776 |
5.4e-144 |
PFAM |
|
Pfam:COPI_C
|
824 |
1233 |
1.4e-190 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000124289
|
| SMART Domains |
Protein: ENSMUSP00000118899
Gene: ENSMUSG00000026553
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:WD40
|
1 |
37 |
2e-19 |
BLAST |
|
PDB:4J8G|B
|
1 |
52 |
2e-23 |
PDB |
|
SCOP:d1erja_
|
1 |
52 |
1e-6 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000135192
AA Change: T286A
PolyPhen 2
Score 0.956 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000118179
Gene: ENSMUSG00000026553
AA Change: T286A
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
2 |
37 |
2.86e0 |
SMART |
|
WD40
|
40 |
79 |
1.11e-6 |
SMART |
|
WD40
|
82 |
121 |
4.76e-6 |
SMART |
|
WD40
|
124 |
163 |
2.24e-11 |
SMART |
|
WD40
|
194 |
233 |
2.98e-7 |
SMART |
|
WD40
|
238 |
277 |
8.42e-7 |
SMART |
|
WD40
|
280 |
318 |
1.38e1 |
SMART |
|
Pfam:Coatomer_WDAD
|
338 |
767 |
1.1e-148 |
PFAM |
|
Pfam:COPI_C
|
815 |
1224 |
3.6e-216 |
PFAM |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000123214
Gene: ENSMUSG00000026553
AA Change: T61A
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
14 |
53 |
8.42e-7 |
SMART |
|
WD40
|
56 |
94 |
1.38e1 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 98.8%
|
| Validation Efficiency |
99% (80/81) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
All alleles(6) : Gene trapped(6)
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abra |
G |
A |
15: 41,729,555 (GRCm39) |
R282C |
probably damaging |
Het |
| Adcy2 |
T |
A |
13: 68,882,794 (GRCm39) |
E314D |
possibly damaging |
Het |
| Adgrl2 |
A |
T |
3: 148,523,402 (GRCm39) |
I274N |
|
Het |
| Adpgk |
A |
G |
9: 59,221,069 (GRCm39) |
I292V |
probably benign |
Het |
| Agtrap |
G |
T |
4: 148,165,054 (GRCm39) |
F124L |
probably benign |
Het |
| Ankrd26 |
A |
G |
6: 118,485,525 (GRCm39) |
Y1450H |
probably damaging |
Het |
| Ap4e1 |
A |
T |
2: 126,903,896 (GRCm39) |
S933C |
probably damaging |
Het |
| Ap4e1 |
G |
T |
2: 126,903,897 (GRCm39) |
S933I |
possibly damaging |
Het |
| Ap5s1 |
A |
T |
2: 131,054,572 (GRCm39) |
T128S |
possibly damaging |
Het |
| Arih1 |
T |
C |
9: 59,393,341 (GRCm39) |
Y97C |
probably damaging |
Het |
| Atp1a3 |
A |
G |
7: 24,678,251 (GRCm39) |
F1034S |
unknown |
Het |
| Bmp6 |
T |
C |
13: 38,669,879 (GRCm39) |
S388P |
probably benign |
Het |
| Ccdc39 |
A |
G |
3: 33,886,825 (GRCm39) |
V261A |
possibly damaging |
Het |
| Ccdc66 |
C |
T |
14: 27,222,293 (GRCm39) |
C150Y |
probably damaging |
Het |
| Cep89 |
G |
A |
7: 35,129,353 (GRCm39) |
R630H |
probably damaging |
Het |
| Cln6 |
A |
G |
9: 62,756,458 (GRCm39) |
S201G |
probably benign |
Het |
| Cntnap4 |
T |
C |
8: 113,391,909 (GRCm39) |
Y125H |
probably damaging |
Het |
| Cul9 |
A |
T |
17: 46,821,919 (GRCm39) |
I1852K |
possibly damaging |
Het |
| Cyp2j8 |
C |
A |
4: 96,332,877 (GRCm39) |
A490S |
probably benign |
Het |
| Cyp2t4 |
A |
G |
7: 26,856,676 (GRCm39) |
I239V |
probably benign |
Het |
| Dpcd |
A |
G |
19: 45,560,905 (GRCm39) |
Y111C |
probably damaging |
Het |
| E2f7 |
C |
T |
10: 110,616,836 (GRCm39) |
T692I |
probably damaging |
Het |
| Fastkd5 |
A |
G |
2: 130,457,055 (GRCm39) |
Y512H |
probably damaging |
Het |
| Fastkd5 |
A |
C |
2: 130,458,359 (GRCm39) |
M77R |
probably benign |
Het |
| Fhod3 |
A |
G |
18: 25,223,524 (GRCm39) |
R957G |
possibly damaging |
Het |
| H6pd |
C |
A |
4: 150,068,359 (GRCm39) |
|
probably null |
Het |
| Haus5 |
G |
T |
7: 30,356,391 (GRCm39) |
P544Q |
possibly damaging |
Het |
| Ifi207 |
CTGTTGATGAAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATACAGTTGCTTGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATAGAGTTGCATATGGAGCCAGGAGGATGCTATATGTTGTTGATGAAGTTGCATGTGGAGCCAGGAG |
CTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGTTGTTGATAGAGTTGCATGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATACAGTTGCTTGTGGAGCCAGGAGGTTGCTAGATGCTGTTGATAGAGTTGCATATGGAGCCAGGAGGATGCTATATGTTGTTGATGAAGTTGCATGTGGAGCCAGGAG |
1: 173,556,762 (GRCm39) |
|
probably benign |
Het |
| Igf2r |
A |
G |
17: 12,922,371 (GRCm39) |
Y1248H |
probably damaging |
Het |
| Izumo3 |
T |
C |
4: 92,035,455 (GRCm39) |
N6S |
possibly damaging |
Het |
| Lrp6 |
G |
T |
6: 134,427,781 (GRCm39) |
P1604T |
probably damaging |
Het |
| Map3k8 |
T |
A |
18: 4,340,561 (GRCm39) |
H251L |
probably damaging |
Het |
| Mapre3 |
T |
C |
5: 31,019,173 (GRCm39) |
Y6H |
probably benign |
Het |
| Mlh3 |
G |
T |
12: 85,314,215 (GRCm39) |
P657Q |
probably damaging |
Het |
| Mrgpra1 |
T |
C |
7: 46,985,157 (GRCm39) |
Y174C |
probably benign |
Het |
| Ms4a6d |
G |
A |
19: 11,567,437 (GRCm39) |
Q155* |
probably null |
Het |
| Myh1 |
C |
A |
11: 67,093,365 (GRCm39) |
P152Q |
probably damaging |
Het |
| Myh6 |
A |
T |
14: 55,189,716 (GRCm39) |
L1110Q |
probably damaging |
Het |
| Nf1 |
T |
A |
11: 79,427,676 (GRCm39) |
S1778T |
probably benign |
Het |
| Nkpd1 |
G |
A |
7: 19,258,341 (GRCm39) |
E707K |
probably damaging |
Het |
| Nlrp4a |
A |
G |
7: 26,143,698 (GRCm39) |
E21G |
probably damaging |
Het |
| Nr4a3 |
T |
G |
4: 48,051,290 (GRCm39) |
S15A |
possibly damaging |
Het |
| Or2f1 |
T |
C |
6: 42,721,790 (GRCm39) |
L273S |
possibly damaging |
Het |
| Or5p1 |
T |
C |
7: 107,916,920 (GRCm39) |
V273A |
possibly damaging |
Het |
| Or5p64 |
T |
C |
7: 107,855,330 (GRCm39) |
D5G |
probably benign |
Het |
| Or7a38 |
A |
G |
10: 78,753,396 (GRCm39) |
T241A |
probably damaging |
Het |
| Parg |
G |
A |
14: 31,972,036 (GRCm39) |
R677Q |
possibly damaging |
Het |
| Pcsk5 |
A |
T |
19: 17,434,182 (GRCm39) |
C1395* |
probably null |
Het |
| Psd2 |
G |
A |
18: 36,113,389 (GRCm39) |
S287N |
possibly damaging |
Het |
| Psd3 |
T |
C |
8: 68,243,583 (GRCm39) |
N685S |
possibly damaging |
Het |
| Pygb |
C |
T |
2: 150,628,903 (GRCm39) |
T39M |
probably benign |
Het |
| Rbfox1 |
C |
A |
16: 7,225,888 (GRCm39) |
Y351* |
probably null |
Het |
| Rftn1 |
A |
G |
17: 50,311,351 (GRCm39) |
L396P |
probably damaging |
Het |
| S1pr1 |
A |
G |
3: 115,505,710 (GRCm39) |
Y295H |
probably damaging |
Het |
| Scn5a |
T |
C |
9: 119,364,899 (GRCm39) |
M440V |
probably benign |
Het |
| Sel1l2 |
T |
C |
2: 140,107,644 (GRCm39) |
N240S |
probably benign |
Het |
| Skic3 |
T |
C |
13: 76,331,003 (GRCm39) |
F1478L |
possibly damaging |
Het |
| Skint1 |
T |
C |
4: 111,878,770 (GRCm39) |
L234P |
probably damaging |
Het |
| Skint11 |
T |
A |
4: 114,101,919 (GRCm39) |
Y311N |
probably benign |
Het |
| Slc6a5 |
A |
T |
7: 49,559,915 (GRCm39) |
|
probably benign |
Het |
| Tas2r134 |
T |
C |
2: 51,518,414 (GRCm39) |
S298P |
possibly damaging |
Het |
| Tbcd |
C |
A |
11: 121,485,137 (GRCm39) |
A773D |
probably benign |
Het |
| Tgoln1 |
G |
C |
6: 72,593,261 (GRCm39) |
T73R |
probably benign |
Het |
| Tmem184a |
T |
C |
5: 139,799,809 (GRCm39) |
E24G |
probably null |
Het |
| Tmem207 |
C |
A |
16: 26,335,577 (GRCm39) |
W53C |
possibly damaging |
Het |
| Tns1 |
T |
A |
1: 73,956,076 (GRCm39) |
H549L |
possibly damaging |
Het |
| Ttc41 |
G |
T |
10: 86,586,212 (GRCm39) |
E839* |
probably null |
Het |
| Ufd1 |
T |
G |
16: 18,634,635 (GRCm39) |
|
probably benign |
Het |
| Usp28 |
A |
G |
9: 48,942,177 (GRCm39) |
E713G |
probably benign |
Het |
| Utrn |
A |
G |
10: 12,623,762 (GRCm39) |
W159R |
probably damaging |
Het |
| Vcl |
C |
T |
14: 21,053,218 (GRCm39) |
A411V |
probably benign |
Het |
| Vcl |
T |
A |
14: 21,059,020 (GRCm39) |
C545* |
probably null |
Het |
| Vmn1r120 |
A |
T |
7: 20,787,377 (GRCm39) |
S111R |
probably damaging |
Het |
| Wwox |
T |
A |
8: 115,199,392 (GRCm39) |
C146S |
probably benign |
Het |
| Zbtb2 |
T |
C |
10: 4,324,574 (GRCm39) |
T57A |
possibly damaging |
Het |
| Zfp362 |
T |
C |
4: 128,671,010 (GRCm39) |
D336G |
possibly damaging |
Het |
| Zfp628 |
G |
A |
7: 4,924,817 (GRCm39) |
G1013E |
probably damaging |
Het |
| Zfp704 |
A |
G |
3: 9,539,658 (GRCm39) |
S231P |
probably damaging |
Het |
| Zhx3 |
G |
T |
2: 160,624,038 (GRCm39) |
S43* |
probably null |
Het |
|
| Other mutations in Copa |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00848:Copa
|
APN |
1 |
171,938,255 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01360:Copa
|
APN |
1 |
171,915,155 (GRCm39) |
splice site |
probably null |
|
|
IGL01434:Copa
|
APN |
1 |
171,947,128 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01744:Copa
|
APN |
1 |
171,940,756 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01837:Copa
|
APN |
1 |
171,946,419 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01988:Copa
|
APN |
1 |
171,945,831 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02059:Copa
|
APN |
1 |
171,927,320 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02123:Copa
|
APN |
1 |
171,939,695 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02731:Copa
|
APN |
1 |
171,929,785 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL03114:Copa
|
APN |
1 |
171,946,835 (GRCm39) |
nonsense |
probably null |
|
|
P0027:Copa
|
UTSW |
1 |
171,939,515 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
PIT4434001:Copa
|
UTSW |
1 |
171,933,742 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0233:Copa
|
UTSW |
1 |
171,915,234 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0465:Copa
|
UTSW |
1 |
171,945,872 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0547:Copa
|
UTSW |
1 |
171,949,254 (GRCm39) |
splice site |
probably benign |
|
|
R0568:Copa
|
UTSW |
1 |
171,939,704 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0628:Copa
|
UTSW |
1 |
171,918,592 (GRCm39) |
splice site |
probably benign |
|
|
R1328:Copa
|
UTSW |
1 |
171,949,258 (GRCm39) |
splice site |
probably benign |
|
|
R1494:Copa
|
UTSW |
1 |
171,931,694 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1728:Copa
|
UTSW |
1 |
171,939,554 (GRCm39) |
missense |
probably benign |
|
|
R1758:Copa
|
UTSW |
1 |
171,931,711 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1784:Copa
|
UTSW |
1 |
171,939,554 (GRCm39) |
missense |
probably benign |
|
|
R1942:Copa
|
UTSW |
1 |
171,939,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2054:Copa
|
UTSW |
1 |
171,946,524 (GRCm39) |
nonsense |
probably null |
|
|
R2299:Copa
|
UTSW |
1 |
171,949,292 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2518:Copa
|
UTSW |
1 |
171,947,468 (GRCm39) |
missense |
probably benign |
|
|
R2680:Copa
|
UTSW |
1 |
171,948,971 (GRCm39) |
nonsense |
probably null |
|
|
R3080:Copa
|
UTSW |
1 |
171,940,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3160:Copa
|
UTSW |
1 |
171,918,800 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3161:Copa
|
UTSW |
1 |
171,918,800 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3162:Copa
|
UTSW |
1 |
171,918,800 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3162:Copa
|
UTSW |
1 |
171,918,800 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3973:Copa
|
UTSW |
1 |
171,948,812 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3975:Copa
|
UTSW |
1 |
171,948,812 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4031:Copa
|
UTSW |
1 |
171,935,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4155:Copa
|
UTSW |
1 |
171,928,992 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4227:Copa
|
UTSW |
1 |
171,945,682 (GRCm39) |
intron |
probably benign |
|
|
R4244:Copa
|
UTSW |
1 |
171,938,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4254:Copa
|
UTSW |
1 |
171,929,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4291:Copa
|
UTSW |
1 |
171,919,964 (GRCm39) |
intron |
probably benign |
|
|
R4323:Copa
|
UTSW |
1 |
171,946,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4402:Copa
|
UTSW |
1 |
171,929,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4711:Copa
|
UTSW |
1 |
171,947,555 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4721:Copa
|
UTSW |
1 |
171,931,841 (GRCm39) |
splice site |
probably benign |
|
|
R4773:Copa
|
UTSW |
1 |
171,932,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4794:Copa
|
UTSW |
1 |
171,946,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4887:Copa
|
UTSW |
1 |
171,919,843 (GRCm39) |
missense |
probably benign |
0.39 |
|
R4953:Copa
|
UTSW |
1 |
171,910,453 (GRCm39) |
unclassified |
probably benign |
|
|
R5139:Copa
|
UTSW |
1 |
171,948,896 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5152:Copa
|
UTSW |
1 |
171,945,628 (GRCm39) |
missense |
probably benign |
0.34 |
|
R5297:Copa
|
UTSW |
1 |
171,940,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5586:Copa
|
UTSW |
1 |
171,932,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5698:Copa
|
UTSW |
1 |
171,946,511 (GRCm39) |
nonsense |
probably null |
|
|
R6283:Copa
|
UTSW |
1 |
171,946,415 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R6921:Copa
|
UTSW |
1 |
171,939,491 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6934:Copa
|
UTSW |
1 |
171,938,253 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R7009:Copa
|
UTSW |
1 |
171,918,567 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7194:Copa
|
UTSW |
1 |
171,947,511 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7710:Copa
|
UTSW |
1 |
171,937,411 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7745:Copa
|
UTSW |
1 |
171,939,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7893:Copa
|
UTSW |
1 |
171,947,132 (GRCm39) |
nonsense |
probably null |
|
|
R8168:Copa
|
UTSW |
1 |
171,927,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8273:Copa
|
UTSW |
1 |
171,946,546 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8704:Copa
|
UTSW |
1 |
171,931,693 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8754:Copa
|
UTSW |
1 |
171,935,926 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8757:Copa
|
UTSW |
1 |
171,947,081 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8759:Copa
|
UTSW |
1 |
171,947,081 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8885:Copa
|
UTSW |
1 |
171,925,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8891:Copa
|
UTSW |
1 |
171,946,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8927:Copa
|
UTSW |
1 |
171,931,737 (GRCm39) |
missense |
probably null |
0.03 |
|
R8928:Copa
|
UTSW |
1 |
171,931,737 (GRCm39) |
missense |
probably null |
0.03 |
|
R8956:Copa
|
UTSW |
1 |
171,937,480 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9063:Copa
|
UTSW |
1 |
171,944,529 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9295:Copa
|
UTSW |
1 |
171,939,823 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9364:Copa
|
UTSW |
1 |
171,944,831 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9437:Copa
|
UTSW |
1 |
171,931,712 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9673:Copa
|
UTSW |
1 |
171,945,648 (GRCm39) |
missense |
probably benign |
0.11 |
|
T0722:Copa
|
UTSW |
1 |
171,939,515 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
Z1177:Copa
|
UTSW |
1 |
171,933,690 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GTTAGTGTGAAGCCTTCCCTCC -3'
(R):5'- GGCTCTGAAAACTCTGCTTCTC -3'
Sequencing Primer
(F):5'- CCCACTGTGTTCCTTGTGGG -3'
(R):5'- GAAAACTCTGCTTCTCTTTGTTTTC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation