Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00429:F830016B08Rik'

5709

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

F830016B08Rik

Ensembl Gene

ENSMUSG00000090942

Gene Name

RIKEN cDNA F830016B08 gene

Synonyms

Ifgga4

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.059) question?

Stock #

IGL00429

Quality Score

Status

Chromosome

Chromosomal Location

60426452-60436088 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 60433340 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Glutamine at position 141 (L141Q)

Ref Sequence

ENSEMBL: ENSMUSP00000131437 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000171297]

AlphaFold

G3UWE2

Predicted Effect

probably damaging
Transcript: ENSMUST00000171297
AA Change: L141Q

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000131437
Gene: ENSMUSG00000090942
AA Change: L141Q

Domain	Start	End	E-Value	Type
Pfam:IIGP	35	405	1.1e-131	PFAM
Pfam:ABC_tran	68	214	7.3e-7	PFAM
Pfam:MMR_HSR1	71	197	2.2e-10	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 44 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700009J07Rik	G	A	10: 77,729,673 (GRCm39)		probably benign	Het
4933411K16Rik	T	C	19: 42,040,983 (GRCm39)	L38P	probably damaging	Het
Abca1	A	G	4: 53,059,255 (GRCm39)		probably null	Het
Abca15	T	A	7: 119,996,277 (GRCm39)	I1401N	probably damaging	Het
Adam3	A	C	8: 25,184,294 (GRCm39)	Y569D	probably damaging	Het
Ap2a1	T	C	7: 44,555,192 (GRCm39)	S458G	probably damaging	Het
Asxl3	C	T	18: 22,658,280 (GRCm39)	P2097S	probably benign	Het
AW551984	T	C	9: 39,504,145 (GRCm39)	D607G	probably benign	Het
Ccdc158	C	A	5: 92,805,740 (GRCm39)	M338I	probably benign	Het
Cdh23	A	G	10: 60,256,920 (GRCm39)	S735P	probably damaging	Het
Cdh9	T	C	15: 16,828,448 (GRCm39)	V180A	probably damaging	Het
Cyp4a31	A	T	4: 115,432,171 (GRCm39)		probably benign	Het
Dus4l	A	G	12: 31,691,668 (GRCm39)	V180A	probably benign	Het
Dysf	A	T	6: 84,166,826 (GRCm39)	T1672S	probably damaging	Het
Fhod3	A	G	18: 25,127,597 (GRCm39)	E313G	probably damaging	Het
Gm4884	A	G	7: 40,693,809 (GRCm39)	T593A	probably benign	Het
H2bc14	T	C	13: 21,906,310 (GRCm39)	S15P	possibly damaging	Het
Il18r1	G	A	1: 40,537,812 (GRCm39)	E526K	possibly damaging	Het
Lama4	A	T	10: 38,887,022 (GRCm39)	H109L	possibly damaging	Het
Mab21l1	A	C	3: 55,690,557 (GRCm39)	Q48P	probably damaging	Het
Magi3	T	A	3: 103,922,294 (GRCm39)	K1474N	probably damaging	Het
Mre11a	T	C	9: 14,714,109 (GRCm39)	F237L	probably damaging	Het
Mst1r	A	T	9: 107,790,449 (GRCm39)		probably benign	Het
Mtcl2	A	C	2: 156,872,784 (GRCm39)	F909C	probably damaging	Het
Myh2	C	T	11: 67,071,616 (GRCm39)	Q478*	probably null	Het
Mylip	C	A	13: 45,562,043 (GRCm39)	P282T	probably benign	Het
Mymk	T	C	2: 26,952,799 (GRCm39)	Y103C	probably damaging	Het
Necab1	A	T	4: 15,052,656 (GRCm39)	N107K	probably damaging	Het
Pclo	T	C	5: 14,730,753 (GRCm39)		probably benign	Het
Phgdh	T	C	3: 98,235,631 (GRCm39)	K129E	probably damaging	Het
Plxna4	T	C	6: 32,139,026 (GRCm39)	Y1714C	probably damaging	Het
Pm20d2	A	G	4: 33,187,205 (GRCm39)		probably benign	Het
Ppfibp2	A	G	7: 107,296,801 (GRCm39)	T172A	probably benign	Het
Prkca	T	C	11: 108,234,334 (GRCm39)	T54A	probably benign	Het
Prlr	A	G	15: 10,328,410 (GRCm39)	D295G	probably benign	Het
Rdh12	A	G	12: 79,258,176 (GRCm39)	I68V	probably benign	Het
Slc14a2	A	G	18: 78,193,653 (GRCm39)	F850L	possibly damaging	Het
Smad2	A	T	18: 76,431,566 (GRCm39)	S185C	possibly damaging	Het
Trav13n-4	T	A	14: 53,601,288 (GRCm39)	L19Q	probably benign	Het
Ush2a	T	A	1: 188,132,311 (GRCm39)	C844*	probably null	Het
Vwce	T	A	19: 10,641,875 (GRCm39)		probably null	Het
Wdr95	T	C	5: 149,518,709 (GRCm39)		probably benign	Het
Zfp143	T	C	7: 109,690,979 (GRCm39)	I510T	probably damaging	Het
Zfp930	G	T	8: 69,680,634 (GRCm39)	K90N	probably damaging	Het

Other mutations in F830016B08Rik

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02642:F830016B08Rik	APN	18	60,433,058 (GRCm39)	missense	probably benign	0.00
FR4342:F830016B08Rik	UTSW	18	60,433,013 (GRCm39)	small insertion	probably benign
R0172:F830016B08Rik	UTSW	18	60,433,036 (GRCm39)	missense	possibly damaging	0.64
R0375:F830016B08Rik	UTSW	18	60,433,265 (GRCm39)	missense	probably damaging	1.00
R1517:F830016B08Rik	UTSW	18	60,433,970 (GRCm39)	nonsense	probably null
R1791:F830016B08Rik	UTSW	18	60,433,589 (GRCm39)	missense	probably benign	0.01
R2413:F830016B08Rik	UTSW	18	60,433,365 (GRCm39)	nonsense	probably null
R2696:F830016B08Rik	UTSW	18	60,433,808 (GRCm39)	missense	possibly damaging	0.75
R3607:F830016B08Rik	UTSW	18	60,433,780 (GRCm39)	nonsense	probably null
R4612:F830016B08Rik	UTSW	18	60,434,087 (GRCm39)	missense	probably benign	0.42
R4621:F830016B08Rik	UTSW	18	60,433,939 (GRCm39)	missense	probably benign	0.01
R4752:F830016B08Rik	UTSW	18	60,434,153 (GRCm39)	missense	probably benign	0.00
R5755:F830016B08Rik	UTSW	18	60,433,878 (GRCm39)	missense	probably damaging	1.00
R5909:F830016B08Rik	UTSW	18	60,433,091 (GRCm39)	missense	probably damaging	1.00
R6183:F830016B08Rik	UTSW	18	60,432,949 (GRCm39)	missense	probably benign	0.00
R6272:F830016B08Rik	UTSW	18	60,433,150 (GRCm39)	missense	probably damaging	1.00
R7076:F830016B08Rik	UTSW	18	60,433,543 (GRCm39)	missense	probably damaging	1.00
R8130:F830016B08Rik	UTSW	18	60,433,052 (GRCm39)	missense	probably benign	0.00
R8171:F830016B08Rik	UTSW	18	60,433,150 (GRCm39)	missense	possibly damaging	0.94
R8289:F830016B08Rik	UTSW	18	60,433,360 (GRCm39)	missense	probably benign	0.45
R9034:F830016B08Rik	UTSW	18	60,433,141 (GRCm39)	missense	probably damaging	0.96
R9600:F830016B08Rik	UTSW	18	60,433,237 (GRCm39)	missense	probably damaging	0.99
R9614:F830016B08Rik	UTSW	18	60,433,379 (GRCm39)	missense	probably damaging	1.00
R9633:F830016B08Rik	UTSW	18	60,432,965 (GRCm39)	missense	probably damaging	0.99
R9638:F830016B08Rik	UTSW	18	60,432,956 (GRCm39)	missense	probably benign	0.00
R9684:F830016B08Rik	UTSW	18	60,433,043 (GRCm39)	missense	probably damaging	0.97
R9729:F830016B08Rik	UTSW	18	60,433,558 (GRCm39)	missense	possibly damaging	0.88
RF044:F830016B08Rik	UTSW	18	60,433,010 (GRCm39)	small insertion	probably benign
RF054:F830016B08Rik	UTSW	18	60,433,010 (GRCm39)	small insertion	probably benign

Posted On

2012-04-20