Incidental Mutation 'R7365:Clca3a2'
| ID |
571690 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Clca3a2
|
| Ensembl Gene |
ENSMUSG00000028262 |
| Gene Name |
chloride channel accessory 3A2 |
| Synonyms |
Clca2 |
| MMRRC Submission |
045449-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.089)
|
| Stock # |
R7365 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
144502320-144525255 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 144804545 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 61
(I61F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000036029
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040465]
[ENSMUST00000198993]
|
| AlphaFold |
Q9EQR4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000040465
AA Change: I61F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000036029
Gene: ENSMUSG00000036960
AA Change: I61F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
29 |
N/A |
INTRINSIC |
|
VWA
|
309 |
485 |
3.55e-5 |
SMART |
|
low complexity region
|
739 |
754 |
N/A |
INTRINSIC |
|
Blast:FN3
|
765 |
875 |
5e-21 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000198993
AA Change: I61F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000143161
Gene: ENSMUSG00000036960
AA Change: I61F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:CLCA_N
|
7 |
265 |
1.7e-121 |
PFAM |
|
VWA
|
309 |
485 |
2.2e-7 |
SMART |
|
Pfam:DUF1973
|
494 |
674 |
7.8e-75 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
100% (96/96) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700123K08Rik |
T |
C |
5: 138,561,198 (GRCm39) |
S155G |
probably benign |
Het |
| Abcc4 |
T |
C |
14: 118,865,066 (GRCm39) |
N320S |
probably damaging |
Het |
| Akr1c19 |
G |
A |
13: 4,287,069 (GRCm39) |
R96H |
probably benign |
Het |
| Ankrd17 |
T |
C |
5: 90,439,010 (GRCm39) |
D451G |
possibly damaging |
Het |
| Ano8 |
T |
A |
8: 71,937,754 (GRCm39) |
D36V |
probably damaging |
Het |
| Aqp3 |
A |
G |
4: 41,098,003 (GRCm39) |
V36A |
probably benign |
Het |
| Atf7ip |
A |
G |
6: 136,537,708 (GRCm39) |
T314A |
probably benign |
Het |
| Atp2c1 |
A |
T |
9: 105,300,198 (GRCm39) |
D700E |
probably damaging |
Het |
| Axin2 |
G |
A |
11: 108,830,202 (GRCm39) |
V341M |
possibly damaging |
Het |
| Bin3 |
A |
G |
14: 70,371,976 (GRCm39) |
Q139R |
probably damaging |
Het |
| Brca2 |
A |
G |
5: 150,455,802 (GRCm39) |
D181G |
probably damaging |
Het |
| Capn3 |
A |
G |
2: 120,325,295 (GRCm39) |
E466G |
probably damaging |
Het |
| Ccdc14 |
T |
A |
16: 34,543,989 (GRCm39) |
Y830* |
probably null |
Het |
| Cdk12 |
T |
C |
11: 98,111,910 (GRCm39) |
F723L |
unknown |
Het |
| Cep89 |
G |
A |
7: 35,129,353 (GRCm39) |
R630H |
probably damaging |
Het |
| Cip2a |
T |
A |
16: 48,822,016 (GRCm39) |
S215T |
probably benign |
Het |
| Clca4b |
T |
C |
3: 144,628,529 (GRCm39) |
T393A |
not run |
Het |
| Cldn5 |
G |
A |
16: 18,595,845 (GRCm39) |
A34T |
probably damaging |
Het |
| Cobll1 |
A |
T |
2: 64,928,717 (GRCm39) |
S870T |
probably damaging |
Het |
| Col12a1 |
T |
C |
9: 79,613,642 (GRCm39) |
K68E |
probably damaging |
Het |
| Crnn |
A |
T |
3: 93,055,841 (GRCm39) |
Q209L |
probably damaging |
Het |
| Cwf19l1 |
A |
T |
19: 44,120,579 (GRCm39) |
F45I |
probably damaging |
Het |
| Cyfip2 |
T |
A |
11: 46,098,267 (GRCm39) |
K1052* |
probably null |
Het |
| D930020B18Rik |
G |
A |
10: 121,503,716 (GRCm39) |
|
probably null |
Het |
| Dcc |
G |
A |
18: 71,959,194 (GRCm39) |
P193S |
probably damaging |
Het |
| Dda1 |
T |
A |
8: 71,927,137 (GRCm39) |
C48S |
probably benign |
Het |
| Disc1 |
A |
G |
8: 125,881,780 (GRCm39) |
R572G |
probably damaging |
Het |
| Dnah7a |
A |
T |
1: 53,536,297 (GRCm39) |
M2582K |
probably benign |
Het |
| Dsel |
C |
T |
1: 111,789,303 (GRCm39) |
G411S |
probably damaging |
Het |
| Dynlrb2 |
T |
C |
8: 117,241,696 (GRCm39) |
V80A |
probably benign |
Het |
| Eif3a |
A |
T |
19: 60,755,082 (GRCm39) |
D1033E |
unknown |
Het |
| Enam |
C |
A |
5: 88,649,347 (GRCm39) |
H285Q |
possibly damaging |
Het |
| Ep400 |
T |
C |
5: 110,867,480 (GRCm39) |
D980G |
unknown |
Het |
| Epha7 |
C |
T |
4: 28,871,937 (GRCm39) |
S422L |
probably benign |
Het |
| Erc2 |
A |
C |
14: 27,762,346 (GRCm39) |
D703A |
probably damaging |
Het |
| Ezh2 |
G |
T |
6: 47,510,692 (GRCm39) |
S639* |
probably null |
Het |
| Fbn1 |
G |
A |
2: 125,193,969 (GRCm39) |
H1333Y |
probably damaging |
Het |
| Flad1 |
A |
G |
3: 89,315,972 (GRCm39) |
S197P |
possibly damaging |
Het |
| Foxl3 |
A |
G |
5: 138,806,736 (GRCm39) |
H82R |
probably damaging |
Het |
| Gfm2 |
G |
T |
13: 97,279,529 (GRCm39) |
C26F |
probably benign |
Het |
| Golga2 |
C |
T |
2: 32,193,013 (GRCm39) |
Q444* |
probably null |
Het |
| Gp5 |
A |
T |
16: 30,127,426 (GRCm39) |
V416D |
probably damaging |
Het |
| Gpat2 |
A |
G |
2: 127,268,901 (GRCm39) |
|
probably null |
Het |
| Gpr137c |
A |
G |
14: 45,516,471 (GRCm39) |
D353G |
probably damaging |
Het |
| Hoxa13 |
A |
C |
6: 52,236,862 (GRCm39) |
W133G |
probably damaging |
Het |
| Hydin |
A |
T |
8: 111,284,294 (GRCm39) |
I3189F |
probably damaging |
Het |
| Hydin |
A |
T |
8: 111,327,905 (GRCm39) |
K4804M |
probably damaging |
Het |
| Ice2 |
T |
C |
9: 69,307,794 (GRCm39) |
F26S |
probably damaging |
Het |
| Ints11 |
T |
C |
4: 155,956,687 (GRCm39) |
|
probably null |
Het |
| Ipo5 |
A |
G |
14: 121,157,497 (GRCm39) |
I112V |
probably benign |
Het |
| Itgax |
T |
A |
7: 127,734,481 (GRCm39) |
S346R |
probably damaging |
Het |
| Kcnj13 |
T |
A |
1: 87,316,739 (GRCm39) |
M125L |
probably damaging |
Het |
| Lmbrd1 |
T |
A |
1: 24,783,948 (GRCm39) |
V359E |
possibly damaging |
Het |
| Lrrc7 |
T |
G |
3: 157,903,798 (GRCm39) |
K287N |
probably damaging |
Het |
| Mau2 |
C |
T |
8: 70,481,884 (GRCm39) |
A191T |
possibly damaging |
Het |
| Mkx |
C |
A |
18: 7,000,747 (GRCm39) |
R65L |
possibly damaging |
Het |
| Mroh4 |
T |
A |
15: 74,482,220 (GRCm39) |
K746* |
probably null |
Het |
| Myh4 |
A |
G |
11: 67,133,674 (GRCm39) |
T238A |
probably damaging |
Het |
| Nlrp9c |
T |
A |
7: 26,070,822 (GRCm39) |
N920Y |
possibly damaging |
Het |
| Nr4a3 |
T |
G |
4: 48,051,290 (GRCm39) |
S15A |
possibly damaging |
Het |
| Ntn4 |
T |
C |
10: 93,480,666 (GRCm39) |
L130P |
probably damaging |
Het |
| Or2ag13 |
A |
G |
7: 106,313,171 (GRCm39) |
V239A |
probably benign |
Het |
| Or4a68 |
A |
G |
2: 89,270,542 (GRCm39) |
V27A |
probably benign |
Het |
| Or4f59 |
A |
T |
2: 111,873,359 (GRCm39) |
V6E |
possibly damaging |
Het |
| Or56a42-ps1 |
T |
A |
7: 104,777,552 (GRCm39) |
I21F |
probably benign |
Het |
| Or8d23 |
A |
T |
9: 38,842,072 (GRCm39) |
I202F |
probably damaging |
Het |
| Otog |
T |
C |
7: 45,947,732 (GRCm39) |
L110P |
probably damaging |
Het |
| Platr25 |
G |
A |
13: 62,848,719 (GRCm39) |
H48Y |
probably benign |
Het |
| Plcxd2 |
T |
C |
16: 45,800,789 (GRCm39) |
E145G |
probably damaging |
Het |
| Pltp |
A |
T |
2: 164,696,242 (GRCm39) |
N143K |
probably damaging |
Het |
| Pnpt1 |
T |
C |
11: 29,111,334 (GRCm39) |
Y735H |
probably damaging |
Het |
| Prom1 |
A |
G |
5: 44,178,173 (GRCm39) |
Y520H |
probably damaging |
Het |
| Rag2 |
A |
G |
2: 101,461,118 (GRCm39) |
Y476C |
probably damaging |
Het |
| Rdh16f2 |
A |
G |
10: 127,712,893 (GRCm39) |
Y297C |
probably damaging |
Het |
| Ryr1 |
T |
C |
7: 28,785,180 (GRCm39) |
E1844G |
probably benign |
Het |
| Ryr2 |
A |
G |
13: 11,655,161 (GRCm39) |
C3679R |
probably damaging |
Het |
| Sirt1 |
A |
G |
10: 63,157,782 (GRCm39) |
I544T |
probably benign |
Het |
| Slc26a10 |
A |
T |
10: 127,012,716 (GRCm39) |
I382N |
possibly damaging |
Het |
| Sox2 |
C |
A |
3: 34,705,121 (GRCm39) |
P186Q |
possibly damaging |
Het |
| Spata31e5 |
A |
T |
1: 28,819,233 (GRCm39) |
M16K |
probably benign |
Het |
| Tnpo3 |
A |
G |
6: 29,556,995 (GRCm39) |
L752P |
probably damaging |
Het |
| Top2b |
T |
A |
14: 16,416,649 (GRCm38) |
N1136K |
probably benign |
Het |
| Tpsg1 |
G |
T |
17: 25,592,184 (GRCm39) |
G86V |
probably damaging |
Het |
| Ttf2 |
C |
A |
3: 100,870,618 (GRCm39) |
D152Y |
possibly damaging |
Het |
| Txndc15 |
T |
C |
13: 55,862,601 (GRCm39) |
L4P |
unknown |
Het |
| Unc5a |
T |
C |
13: 55,144,386 (GRCm39) |
V237A |
possibly damaging |
Het |
| Urb1 |
CACTTAC |
CAC |
16: 90,569,461 (GRCm39) |
|
probably benign |
Het |
| Vav3 |
C |
A |
3: 109,535,415 (GRCm39) |
P616T |
possibly damaging |
Het |
| Vmn2r15 |
T |
A |
5: 109,441,105 (GRCm39) |
D251V |
probably benign |
Het |
| Vmn2r15 |
A |
G |
5: 109,445,388 (GRCm39) |
L12S |
probably benign |
Het |
| Wfs1 |
A |
C |
5: 37,125,076 (GRCm39) |
I605S |
probably benign |
Het |
| Wif1 |
G |
A |
10: 120,919,814 (GRCm39) |
R187Q |
possibly damaging |
Het |
| Yipf1 |
A |
G |
4: 107,207,738 (GRCm39) |
|
probably null |
Het |
| Zdhhc20 |
G |
T |
14: 58,111,377 (GRCm39) |
F74L |
possibly damaging |
Het |
| Zfp507 |
T |
C |
7: 35,475,843 (GRCm39) |
T303A |
unknown |
Het |
| Zfp763 |
A |
T |
17: 33,252,352 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Clca3a2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00419:Clca3a2
|
APN |
3 |
144,804,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01019:Clca3a2
|
APN |
3 |
144,519,388 (GRCm39) |
nonsense |
probably null |
|
|
IGL01337:Clca3a2
|
APN |
3 |
144,800,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01389:Clca3a2
|
APN |
3 |
144,783,629 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01595:Clca3a2
|
APN |
3 |
144,793,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01663:Clca3a2
|
APN |
3 |
144,522,916 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01704:Clca3a2
|
APN |
3 |
144,800,979 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01779:Clca3a2
|
APN |
3 |
144,525,139 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02066:Clca3a2
|
APN |
3 |
144,519,216 (GRCm39) |
missense |
probably benign |
|
|
IGL02301:Clca3a2
|
APN |
3 |
144,512,133 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02416:Clca3a2
|
APN |
3 |
144,790,777 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02455:Clca3a2
|
APN |
3 |
144,787,172 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02481:Clca3a2
|
APN |
3 |
144,790,701 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02526:Clca3a2
|
APN |
3 |
144,793,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02619:Clca3a2
|
APN |
3 |
144,512,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02797:Clca3a2
|
APN |
3 |
144,787,024 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02852:Clca3a2
|
APN |
3 |
144,512,104 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02901:Clca3a2
|
APN |
3 |
144,522,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03162:Clca3a2
|
APN |
3 |
144,512,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03253:Clca3a2
|
APN |
3 |
144,777,324 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL03256:Clca3a2
|
APN |
3 |
144,792,153 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL03294:Clca3a2
|
APN |
3 |
144,803,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3370:Clca3a2
|
UTSW |
3 |
144,783,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0032:Clca3a2
|
UTSW |
3 |
144,522,494 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0244:Clca3a2
|
UTSW |
3 |
144,519,659 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0479:Clca3a2
|
UTSW |
3 |
144,796,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0542:Clca3a2
|
UTSW |
3 |
144,781,571 (GRCm39) |
splice site |
probably benign |
|
|
R0629:Clca3a2
|
UTSW |
3 |
144,778,000 (GRCm39) |
missense |
probably benign |
|
|
R1249:Clca3a2
|
UTSW |
3 |
144,508,765 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1370:Clca3a2
|
UTSW |
3 |
144,519,624 (GRCm39) |
splice site |
probably benign |
|
|
R1488:Clca3a2
|
UTSW |
3 |
144,789,925 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1523:Clca3a2
|
UTSW |
3 |
144,777,405 (GRCm39) |
nonsense |
probably null |
|
|
R1568:Clca3a2
|
UTSW |
3 |
144,781,410 (GRCm39) |
nonsense |
probably null |
|
|
R1586:Clca3a2
|
UTSW |
3 |
144,516,477 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1650:Clca3a2
|
UTSW |
3 |
144,797,973 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1771:Clca3a2
|
UTSW |
3 |
144,787,171 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1776:Clca3a2
|
UTSW |
3 |
144,519,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1797:Clca3a2
|
UTSW |
3 |
144,503,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1869:Clca3a2
|
UTSW |
3 |
144,512,164 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1871:Clca3a2
|
UTSW |
3 |
144,503,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1919:Clca3a2
|
UTSW |
3 |
144,516,457 (GRCm39) |
missense |
probably benign |
|
|
R1923:Clca3a2
|
UTSW |
3 |
144,511,491 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2101:Clca3a2
|
UTSW |
3 |
144,783,699 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2200:Clca3a2
|
UTSW |
3 |
144,519,685 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2242:Clca3a2
|
UTSW |
3 |
144,796,551 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2324:Clca3a2
|
UTSW |
3 |
144,512,041 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2937:Clca3a2
|
UTSW |
3 |
144,519,679 (GRCm39) |
missense |
probably benign |
0.06 |
|
R3429:Clca3a2
|
UTSW |
3 |
144,512,088 (GRCm39) |
missense |
probably benign |
0.07 |
|
R3434:Clca3a2
|
UTSW |
3 |
144,514,522 (GRCm39) |
unclassified |
probably benign |
|
|
R3551:Clca3a2
|
UTSW |
3 |
144,508,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3751:Clca3a2
|
UTSW |
3 |
144,777,216 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3952:Clca3a2
|
UTSW |
3 |
144,508,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4120:Clca3a2
|
UTSW |
3 |
144,516,613 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4383:Clca3a2
|
UTSW |
3 |
144,512,081 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4496:Clca3a2
|
UTSW |
3 |
144,797,926 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4518:Clca3a2
|
UTSW |
3 |
144,514,466 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4598:Clca3a2
|
UTSW |
3 |
144,511,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4801:Clca3a2
|
UTSW |
3 |
144,513,112 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4802:Clca3a2
|
UTSW |
3 |
144,513,112 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4816:Clca3a2
|
UTSW |
3 |
144,516,613 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4934:Clca3a2
|
UTSW |
3 |
144,523,692 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Clca3a2
|
UTSW |
3 |
144,512,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4962:Clca3a2
|
UTSW |
3 |
144,783,640 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5123:Clca3a2
|
UTSW |
3 |
144,512,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5156:Clca3a2
|
UTSW |
3 |
144,511,599 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5275:Clca3a2
|
UTSW |
3 |
144,519,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5344:Clca3a2
|
UTSW |
3 |
144,793,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5372:Clca3a2
|
UTSW |
3 |
144,503,286 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5424:Clca3a2
|
UTSW |
3 |
144,789,942 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5656:Clca3a2
|
UTSW |
3 |
144,503,393 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5931:Clca3a2
|
UTSW |
3 |
144,797,886 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6059:Clca3a2
|
UTSW |
3 |
144,516,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6155:Clca3a2
|
UTSW |
3 |
144,525,118 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6181:Clca3a2
|
UTSW |
3 |
144,796,469 (GRCm39) |
nonsense |
probably null |
|
|
R6254:Clca3a2
|
UTSW |
3 |
144,507,895 (GRCm39) |
missense |
probably benign |
|
|
R6336:Clca3a2
|
UTSW |
3 |
144,512,239 (GRCm39) |
missense |
probably benign |
|
|
R6470:Clca3a2
|
UTSW |
3 |
144,510,024 (GRCm39) |
splice site |
probably null |
|
|
R6593:Clca3a2
|
UTSW |
3 |
144,514,338 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6598:Clca3a2
|
UTSW |
3 |
144,792,246 (GRCm39) |
nonsense |
probably null |
|
|
R6631:Clca3a2
|
UTSW |
3 |
144,519,405 (GRCm39) |
missense |
probably benign |
|
|
R6826:Clca3a2
|
UTSW |
3 |
144,523,815 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6836:Clca3a2
|
UTSW |
3 |
144,512,144 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6896:Clca3a2
|
UTSW |
3 |
144,514,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7167:Clca3a2
|
UTSW |
3 |
144,803,545 (GRCm39) |
missense |
probably benign |
0.40 |
|
R7211:Clca3a2
|
UTSW |
3 |
144,519,775 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7229:Clca3a2
|
UTSW |
3 |
144,789,869 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7256:Clca3a2
|
UTSW |
3 |
144,796,608 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7324:Clca3a2
|
UTSW |
3 |
144,514,372 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7411:Clca3a2
|
UTSW |
3 |
144,507,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7486:Clca3a2
|
UTSW |
3 |
144,503,362 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7491:Clca3a2
|
UTSW |
3 |
144,519,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7521:Clca3a2
|
UTSW |
3 |
144,507,674 (GRCm39) |
makesense |
probably null |
|
|
R7813:Clca3a2
|
UTSW |
3 |
144,790,726 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7889:Clca3a2
|
UTSW |
3 |
144,516,574 (GRCm39) |
nonsense |
probably null |
|
|
R7946:Clca3a2
|
UTSW |
3 |
144,513,075 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7991:Clca3a2
|
UTSW |
3 |
144,519,756 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8022:Clca3a2
|
UTSW |
3 |
144,511,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8077:Clca3a2
|
UTSW |
3 |
144,777,288 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R8169:Clca3a2
|
UTSW |
3 |
144,783,653 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8290:Clca3a2
|
UTSW |
3 |
144,793,719 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8300:Clca3a2
|
UTSW |
3 |
144,804,692 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8344:Clca3a2
|
UTSW |
3 |
144,511,703 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8350:Clca3a2
|
UTSW |
3 |
144,783,668 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8367:Clca3a2
|
UTSW |
3 |
144,523,508 (GRCm39) |
splice site |
probably null |
|
|
R8371:Clca3a2
|
UTSW |
3 |
144,513,114 (GRCm39) |
nonsense |
probably null |
|
|
R8814:Clca3a2
|
UTSW |
3 |
144,503,525 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8854:Clca3a2
|
UTSW |
3 |
144,783,852 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8876:Clca3a2
|
UTSW |
3 |
144,777,360 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8887:Clca3a2
|
UTSW |
3 |
144,790,810 (GRCm39) |
nonsense |
probably null |
|
|
R9006:Clca3a2
|
UTSW |
3 |
144,783,789 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9031:Clca3a2
|
UTSW |
3 |
144,511,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9069:Clca3a2
|
UTSW |
3 |
144,519,447 (GRCm39) |
splice site |
probably benign |
|
|
R9093:Clca3a2
|
UTSW |
3 |
144,781,481 (GRCm39) |
missense |
probably benign |
0.20 |
|
R9190:Clca3a2
|
UTSW |
3 |
144,796,599 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9201:Clca3a2
|
UTSW |
3 |
144,519,684 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9209:Clca3a2
|
UTSW |
3 |
144,778,005 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9261:Clca3a2
|
UTSW |
3 |
144,525,158 (GRCm39) |
missense |
probably benign |
|
|
R9469:Clca3a2
|
UTSW |
3 |
144,507,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9501:Clca3a2
|
UTSW |
3 |
144,777,322 (GRCm39) |
nonsense |
probably null |
|
|
R9515:Clca3a2
|
UTSW |
3 |
144,508,808 (GRCm39) |
nonsense |
probably null |
|
|
R9569:Clca3a2
|
UTSW |
3 |
144,513,075 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9664:Clca3a2
|
UTSW |
3 |
144,503,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0025:Clca3a2
|
UTSW |
3 |
144,792,265 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
Z1177:Clca3a2
|
UTSW |
3 |
144,792,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATCGATGTGATGTAGCCAGCATG -3'
(R):5'- AGGCTCCCCGTGAATAAACC -3'
Sequencing Primer
(F):5'- GATGTAGCCAGCATGCCCTTAAC -3'
(R):5'- GGTTTCACTGCAAGATGACC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation