Incidental Mutation 'R7387:Pcnx3'
| ID |
573221 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcnx3
|
| Ensembl Gene |
ENSMUSG00000054874 |
| Gene Name |
pecanex homolog 3 |
| Synonyms |
Pcnxl3 |
| MMRRC Submission |
045469-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7387 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
19 |
| Chromosomal Location |
5714663-5738936 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 5723364 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 1277
(L1277P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109245
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068169]
[ENSMUST00000113615]
|
| AlphaFold |
Q8VI59 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000068169
AA Change: L869P
PolyPhen 2
Score 0.905 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000063786
Gene: ENSMUSG00000054874
AA Change: L869P
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
53 |
N/A |
INTRINSIC |
|
transmembrane domain
|
57 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
370 |
376 |
N/A |
INTRINSIC |
|
transmembrane domain
|
385 |
407 |
N/A |
INTRINSIC |
|
transmembrane domain
|
411 |
428 |
N/A |
INTRINSIC |
|
transmembrane domain
|
441 |
463 |
N/A |
INTRINSIC |
|
transmembrane domain
|
473 |
492 |
N/A |
INTRINSIC |
|
transmembrane domain
|
501 |
523 |
N/A |
INTRINSIC |
|
transmembrane domain
|
538 |
560 |
N/A |
INTRINSIC |
|
transmembrane domain
|
573 |
592 |
N/A |
INTRINSIC |
|
transmembrane domain
|
645 |
667 |
N/A |
INTRINSIC |
|
transmembrane domain
|
669 |
691 |
N/A |
INTRINSIC |
|
low complexity region
|
1011 |
1025 |
N/A |
INTRINSIC |
|
Pfam:Pecanex_C
|
1159 |
1389 |
7.5e-124 |
PFAM |
|
low complexity region
|
1462 |
1479 |
N/A |
INTRINSIC |
|
low complexity region
|
1481 |
1510 |
N/A |
INTRINSIC |
|
low complexity region
|
1525 |
1538 |
N/A |
INTRINSIC |
|
low complexity region
|
1558 |
1569 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113615
AA Change: L1277P
PolyPhen 2
Score 0.330 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000109245
Gene: ENSMUSG00000054874
AA Change: L1277P
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
53 |
N/A |
INTRINSIC |
|
transmembrane domain
|
57 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
438 |
459 |
N/A |
INTRINSIC |
|
low complexity region
|
778 |
784 |
N/A |
INTRINSIC |
|
transmembrane domain
|
793 |
815 |
N/A |
INTRINSIC |
|
transmembrane domain
|
819 |
836 |
N/A |
INTRINSIC |
|
transmembrane domain
|
849 |
871 |
N/A |
INTRINSIC |
|
transmembrane domain
|
881 |
900 |
N/A |
INTRINSIC |
|
transmembrane domain
|
909 |
931 |
N/A |
INTRINSIC |
|
transmembrane domain
|
946 |
968 |
N/A |
INTRINSIC |
|
transmembrane domain
|
981 |
1000 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1053 |
1075 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1077 |
1099 |
N/A |
INTRINSIC |
|
low complexity region
|
1419 |
1433 |
N/A |
INTRINSIC |
|
Pfam:Pecanex_C
|
1570 |
1796 |
5.9e-116 |
PFAM |
|
low complexity region
|
1870 |
1887 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1918 |
N/A |
INTRINSIC |
|
low complexity region
|
1933 |
1946 |
N/A |
INTRINSIC |
|
low complexity region
|
1966 |
1977 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000137313
|
| SMART Domains |
Protein: ENSMUSP00000115217
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
transmembrane domain
|
44 |
66 |
N/A |
INTRINSIC |
|
transmembrane domain
|
79 |
98 |
N/A |
INTRINSIC |
|
transmembrane domain
|
151 |
173 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000116493
Gene: ENSMUSG00000054874
AA Change: L697P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
199 |
205 |
N/A |
INTRINSIC |
|
transmembrane domain
|
214 |
236 |
N/A |
INTRINSIC |
|
transmembrane domain
|
240 |
257 |
N/A |
INTRINSIC |
|
transmembrane domain
|
270 |
292 |
N/A |
INTRINSIC |
|
transmembrane domain
|
302 |
321 |
N/A |
INTRINSIC |
|
transmembrane domain
|
330 |
352 |
N/A |
INTRINSIC |
|
transmembrane domain
|
367 |
389 |
N/A |
INTRINSIC |
|
transmembrane domain
|
402 |
421 |
N/A |
INTRINSIC |
|
transmembrane domain
|
474 |
496 |
N/A |
INTRINSIC |
|
transmembrane domain
|
498 |
520 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930522H14Rik |
A |
G |
4: 109,362,774 (GRCm39) |
Y182H |
probably damaging |
Het |
| Abca6 |
A |
G |
11: 110,093,246 (GRCm39) |
V1009A |
probably benign |
Het |
| Abcg2 |
A |
T |
6: 58,666,609 (GRCm39) |
I573F |
possibly damaging |
Het |
| Adck1 |
A |
G |
12: 88,427,822 (GRCm39) |
T480A |
probably benign |
Het |
| Adcy5 |
T |
C |
16: 35,092,460 (GRCm39) |
I607T |
probably damaging |
Het |
| Add2 |
A |
G |
6: 86,062,997 (GRCm39) |
K52E |
probably damaging |
Het |
| Arid4a |
T |
A |
12: 71,134,270 (GRCm39) |
S1191T |
probably damaging |
Het |
| Atg2a |
G |
T |
19: 6,305,198 (GRCm39) |
C1207F |
possibly damaging |
Het |
| Atg2b |
T |
C |
12: 105,589,034 (GRCm39) |
D1875G |
probably damaging |
Het |
| B3gntl1 |
A |
G |
11: 121,520,741 (GRCm39) |
L224P |
possibly damaging |
Het |
| BC035947 |
A |
G |
1: 78,475,098 (GRCm39) |
V478A |
possibly damaging |
Het |
| Cachd1 |
T |
C |
4: 100,634,375 (GRCm39) |
V17A |
unknown |
Het |
| Cad |
T |
C |
5: 31,219,284 (GRCm39) |
Y669H |
probably damaging |
Het |
| Ccdc110 |
A |
T |
8: 46,395,233 (GRCm39) |
M375L |
probably benign |
Het |
| Cdc6 |
C |
T |
11: 98,799,042 (GRCm39) |
|
probably benign |
Het |
| Cdhr4 |
T |
A |
9: 107,874,111 (GRCm39) |
Y72* |
probably null |
Het |
| Cenpe |
T |
G |
3: 134,952,798 (GRCm39) |
M1496R |
probably benign |
Het |
| Clec4a1 |
T |
G |
6: 122,899,016 (GRCm39) |
C28W |
possibly damaging |
Het |
| Cma2 |
A |
G |
14: 56,210,505 (GRCm39) |
N120S |
probably benign |
Het |
| Cped1 |
A |
T |
6: 22,059,933 (GRCm39) |
I200L |
probably benign |
Het |
| Cpsf1 |
A |
T |
15: 76,486,766 (GRCm39) |
S257T |
possibly damaging |
Het |
| Dnah6 |
G |
A |
6: 73,189,595 (GRCm39) |
Q18* |
probably null |
Het |
| Dpp10 |
T |
C |
1: 123,268,869 (GRCm39) |
E720G |
probably benign |
Het |
| Dus2 |
G |
A |
8: 106,772,619 (GRCm39) |
R243Q |
probably damaging |
Het |
| Dync2h1 |
T |
C |
9: 7,157,932 (GRCm39) |
N769S |
possibly damaging |
Het |
| Ece1 |
T |
A |
4: 137,666,095 (GRCm39) |
I313N |
possibly damaging |
Het |
| Ern1 |
A |
T |
11: 106,312,778 (GRCm39) |
V201E |
probably damaging |
Het |
| Exoc3l |
A |
G |
8: 106,021,605 (GRCm39) |
L141P |
probably damaging |
Het |
| Fam168b |
G |
A |
1: 34,858,789 (GRCm39) |
T131M |
probably damaging |
Het |
| Fez1 |
T |
C |
9: 36,779,108 (GRCm39) |
F262L |
probably damaging |
Het |
| H2-DMa |
T |
C |
17: 34,357,101 (GRCm39) |
Y200H |
probably damaging |
Het |
| H2-Eb1 |
T |
A |
17: 34,533,207 (GRCm39) |
V143D |
probably damaging |
Het |
| Ighv1-39 |
G |
A |
12: 114,878,488 (GRCm39) |
P28S |
probably benign |
Het |
| Inka1 |
C |
T |
9: 107,861,626 (GRCm39) |
R230H |
probably damaging |
Het |
| Iqgap1 |
C |
T |
7: 80,370,738 (GRCm39) |
V1544I |
probably benign |
Het |
| Itga10 |
A |
T |
3: 96,560,094 (GRCm39) |
Q536L |
probably benign |
Het |
| Itih2 |
C |
T |
2: 10,135,319 (GRCm39) |
E24K |
possibly damaging |
Het |
| Itsn2 |
A |
T |
12: 4,689,781 (GRCm39) |
N618I |
probably damaging |
Het |
| Kcnd2 |
T |
A |
6: 21,216,777 (GRCm39) |
S160R |
probably benign |
Het |
| Kif11 |
T |
A |
19: 37,398,204 (GRCm39) |
F677I |
probably damaging |
Het |
| Ldlrad2 |
C |
T |
4: 137,301,828 (GRCm39) |
C18Y |
probably damaging |
Het |
| Lrp4 |
T |
C |
2: 91,306,959 (GRCm39) |
V360A |
probably benign |
Het |
| Lrrtm2 |
T |
C |
18: 35,346,025 (GRCm39) |
T426A |
probably damaging |
Het |
| Mcidas |
T |
C |
13: 113,130,622 (GRCm39) |
F40L |
probably benign |
Het |
| Med27 |
T |
A |
2: 29,303,419 (GRCm39) |
L123Q |
possibly damaging |
Het |
| Mettl2 |
T |
C |
11: 105,023,364 (GRCm39) |
V249A |
probably benign |
Het |
| Mllt6 |
C |
A |
11: 97,565,426 (GRCm39) |
A592D |
probably benign |
Het |
| Mrps5 |
C |
T |
2: 127,442,804 (GRCm39) |
T291I |
probably damaging |
Het |
| Muc16 |
T |
A |
9: 18,553,016 (GRCm39) |
T4426S |
probably benign |
Het |
| Myh1 |
A |
T |
11: 67,099,715 (GRCm39) |
M542L |
probably benign |
Het |
| Nlrp12 |
G |
T |
7: 3,289,831 (GRCm39) |
A227D |
probably damaging |
Het |
| Nlrp14 |
T |
C |
7: 106,782,314 (GRCm39) |
Y504H |
probably damaging |
Het |
| Nr1i2 |
T |
C |
16: 38,086,442 (GRCm39) |
S8G |
probably benign |
Het |
| Ntrk2 |
A |
G |
13: 59,133,793 (GRCm39) |
K524R |
probably damaging |
Het |
| Nup210 |
C |
T |
6: 90,998,378 (GRCm39) |
|
probably null |
Het |
| Ogfr |
GGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGG |
GGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGG |
2: 180,237,059 (GRCm39) |
|
probably benign |
Het |
| Or4c100 |
T |
A |
2: 88,356,744 (GRCm39) |
Y272* |
probably null |
Het |
| Or52e4 |
T |
A |
7: 104,706,297 (GRCm39) |
Y281* |
probably null |
Het |
| Or5h27 |
A |
T |
16: 59,006,699 (GRCm39) |
I49N |
probably damaging |
Het |
| Patl1 |
A |
G |
19: 11,911,094 (GRCm39) |
I525M |
probably benign |
Het |
| Pelp1 |
G |
A |
11: 70,287,425 (GRCm39) |
T461I |
probably damaging |
Het |
| Phf20 |
T |
C |
2: 156,136,160 (GRCm39) |
C660R |
probably damaging |
Het |
| Pkd1l1 |
T |
A |
11: 8,851,203 (GRCm39) |
Y1193F |
|
Het |
| Pknox2 |
G |
T |
9: 36,868,364 (GRCm39) |
|
probably benign |
Het |
| Pml |
T |
C |
9: 58,137,177 (GRCm39) |
T541A |
probably benign |
Het |
| Prss35 |
C |
T |
9: 86,637,974 (GRCm39) |
T248I |
probably damaging |
Het |
| Rccd1 |
T |
A |
7: 79,970,350 (GRCm39) |
N89I |
probably benign |
Het |
| Rcor3 |
T |
C |
1: 191,821,824 (GRCm39) |
|
probably benign |
Het |
| Rreb1 |
A |
G |
13: 38,131,040 (GRCm39) |
E16G |
unknown |
Het |
| Scgb2b12 |
T |
A |
7: 32,026,060 (GRCm39) |
H44L |
probably benign |
Het |
| Sec23ip |
C |
T |
7: 128,346,727 (GRCm39) |
|
probably benign |
Het |
| Sgsm1 |
A |
C |
5: 113,411,566 (GRCm39) |
F720C |
probably damaging |
Het |
| Slc25a51 |
A |
T |
4: 45,399,841 (GRCm39) |
F116L |
possibly damaging |
Het |
| Spats2l |
T |
C |
1: 57,941,293 (GRCm39) |
V253A |
probably damaging |
Het |
| Spopl |
A |
T |
2: 23,427,521 (GRCm39) |
F204I |
probably benign |
Het |
| Sqle |
G |
A |
15: 59,202,603 (GRCm39) |
R519Q |
probably benign |
Het |
| Stil |
T |
G |
4: 114,881,233 (GRCm39) |
H592Q |
probably benign |
Het |
| Strip1 |
T |
A |
3: 107,533,046 (GRCm39) |
S201C |
probably damaging |
Het |
| Tcp11l1 |
C |
A |
2: 104,530,275 (GRCm39) |
A70S |
possibly damaging |
Het |
| Tmem163 |
T |
C |
1: 127,447,180 (GRCm39) |
|
probably null |
Het |
| Tmem184c |
A |
T |
8: 78,324,559 (GRCm39) |
Y310* |
probably null |
Het |
| Tmem30c |
T |
C |
16: 57,090,386 (GRCm39) |
N274D |
probably benign |
Het |
| Trim30c |
T |
A |
7: 104,039,397 (GRCm39) |
I133F |
probably damaging |
Het |
| Vars1 |
C |
T |
17: 35,223,768 (GRCm39) |
Q228* |
probably null |
Het |
| Zdbf2 |
G |
A |
1: 63,343,198 (GRCm39) |
V526I |
possibly damaging |
Het |
| Zfp819 |
T |
G |
7: 43,262,065 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Pcnx3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01616:Pcnx3
|
APN |
19 |
5,717,287 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01667:Pcnx3
|
APN |
19 |
5,736,658 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01704:Pcnx3
|
APN |
19 |
5,717,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01752:Pcnx3
|
APN |
19 |
5,715,365 (GRCm39) |
nonsense |
probably null |
|
|
IGL01791:Pcnx3
|
APN |
19 |
5,723,295 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL01937:Pcnx3
|
APN |
19 |
5,727,691 (GRCm39) |
missense |
probably benign |
|
|
IGL01987:Pcnx3
|
APN |
19 |
5,727,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02073:Pcnx3
|
APN |
19 |
5,729,414 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02417:Pcnx3
|
APN |
19 |
5,736,509 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03143:Pcnx3
|
APN |
19 |
5,735,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
buns
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
Pastries
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
pie
|
UTSW |
19 |
5,717,186 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7096_pcnx3_526
|
UTSW |
19 |
5,722,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
swirls
|
UTSW |
19 |
5,722,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
tip
|
UTSW |
19 |
5,733,808 (GRCm39) |
splice site |
probably benign |
|
|
PIT4453001:Pcnx3
|
UTSW |
19 |
5,722,784 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0234:Pcnx3
|
UTSW |
19 |
5,722,646 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0234:Pcnx3
|
UTSW |
19 |
5,722,646 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0360:Pcnx3
|
UTSW |
19 |
5,715,611 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0687:Pcnx3
|
UTSW |
19 |
5,734,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0718:Pcnx3
|
UTSW |
19 |
5,727,756 (GRCm39) |
splice site |
probably benign |
|
|
R0840:Pcnx3
|
UTSW |
19 |
5,735,729 (GRCm39) |
splice site |
probably null |
|
|
R0907:Pcnx3
|
UTSW |
19 |
5,721,553 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1251:Pcnx3
|
UTSW |
19 |
5,727,210 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1373:Pcnx3
|
UTSW |
19 |
5,715,544 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1467:Pcnx3
|
UTSW |
19 |
5,724,922 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1467:Pcnx3
|
UTSW |
19 |
5,724,922 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1572:Pcnx3
|
UTSW |
19 |
5,735,375 (GRCm39) |
nonsense |
probably null |
|
|
R1602:Pcnx3
|
UTSW |
19 |
5,722,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1628:Pcnx3
|
UTSW |
19 |
5,736,093 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1635:Pcnx3
|
UTSW |
19 |
5,715,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1670:Pcnx3
|
UTSW |
19 |
5,723,343 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:Pcnx3
|
UTSW |
19 |
5,722,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1898:Pcnx3
|
UTSW |
19 |
5,722,615 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2113:Pcnx3
|
UTSW |
19 |
5,721,584 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2147:Pcnx3
|
UTSW |
19 |
5,717,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2358:Pcnx3
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
R2358:Pcnx3
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
R2871:Pcnx3
|
UTSW |
19 |
5,733,774 (GRCm39) |
intron |
probably benign |
|
|
R3699:Pcnx3
|
UTSW |
19 |
5,722,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3712:Pcnx3
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
R3712:Pcnx3
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
R3798:Pcnx3
|
UTSW |
19 |
5,728,696 (GRCm39) |
nonsense |
probably null |
|
|
R3856:Pcnx3
|
UTSW |
19 |
5,728,995 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3953:Pcnx3
|
UTSW |
19 |
5,733,808 (GRCm39) |
splice site |
probably benign |
|
|
R4613:Pcnx3
|
UTSW |
19 |
5,717,247 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4781:Pcnx3
|
UTSW |
19 |
5,737,158 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4816:Pcnx3
|
UTSW |
19 |
5,738,023 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5338:Pcnx3
|
UTSW |
19 |
5,722,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5770:Pcnx3
|
UTSW |
19 |
5,731,607 (GRCm39) |
intron |
probably benign |
|
|
R5950:Pcnx3
|
UTSW |
19 |
5,717,186 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5951:Pcnx3
|
UTSW |
19 |
5,721,708 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5969:Pcnx3
|
UTSW |
19 |
5,735,563 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6543:Pcnx3
|
UTSW |
19 |
5,715,275 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6704:Pcnx3
|
UTSW |
19 |
5,736,515 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R7096:Pcnx3
|
UTSW |
19 |
5,722,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7177:Pcnx3
|
UTSW |
19 |
5,737,527 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7308:Pcnx3
|
UTSW |
19 |
5,736,175 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7488:Pcnx3
|
UTSW |
19 |
5,717,487 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7670:Pcnx3
|
UTSW |
19 |
5,727,210 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7831:Pcnx3
|
UTSW |
19 |
5,735,989 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7850:Pcnx3
|
UTSW |
19 |
5,728,960 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R8120:Pcnx3
|
UTSW |
19 |
5,717,574 (GRCm39) |
missense |
probably benign |
|
|
R8139:Pcnx3
|
UTSW |
19 |
5,715,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8258:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8259:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8261:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8262:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8350:Pcnx3
|
UTSW |
19 |
5,723,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8411:Pcnx3
|
UTSW |
19 |
5,729,618 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8429:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8431:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8443:Pcnx3
|
UTSW |
19 |
5,736,670 (GRCm39) |
missense |
probably benign |
|
|
R8450:Pcnx3
|
UTSW |
19 |
5,723,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8494:Pcnx3
|
UTSW |
19 |
5,725,404 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8790:Pcnx3
|
UTSW |
19 |
5,735,206 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8939:Pcnx3
|
UTSW |
19 |
5,730,347 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9065:Pcnx3
|
UTSW |
19 |
5,717,582 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9070:Pcnx3
|
UTSW |
19 |
5,715,601 (GRCm39) |
missense |
probably benign |
0.33 |
|
X0028:Pcnx3
|
UTSW |
19 |
5,734,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0053:Pcnx3
|
UTSW |
19 |
5,736,650 (GRCm39) |
splice site |
probably null |
|
|
Z1176:Pcnx3
|
UTSW |
19 |
5,737,248 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1177:Pcnx3
|
UTSW |
19 |
5,721,654 (GRCm39) |
missense |
probably benign |
0.17 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTTTCTGGCTAGGACACCAAG -3'
(R):5'- CTGACCTACATTGCACCATGG -3'
Sequencing Primer
(F):5'- TGGCTAGGACACCAAGGCTTC -3'
(R):5'- TACATTGCACCATGGCAGATC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation