Incidental Mutation 'R7391:Mical2'
| ID |
573441 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mical2
|
| Ensembl Gene |
ENSMUSG00000038244 |
| Gene Name |
microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| Synonyms |
4921517J23Rik, Ebitein1, 5330438E18Rik, Micalcl |
| MMRRC Submission |
045473-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.242)
|
| Stock # |
R7391 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
111825063-112012313 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 111919816 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Valine
at position 442
(E442V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000047639
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037991]
[ENSMUST00000050149]
|
| AlphaFold |
Q8BML1
Q9D5U9 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000037991
AA Change: E442V
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000047639
Gene: ENSMUSG00000038244
AA Change: E442V
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
1e-8 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
3.2e-6 |
PFAM |
|
low complexity region
|
175 |
188 |
N/A |
INTRINSIC |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
low complexity region
|
894 |
925 |
N/A |
INTRINSIC |
|
LIM
|
979 |
1033 |
9.91e-10 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000050149
AA Change: E442V
PolyPhen 2
Score 0.982 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000051163
Gene: ENSMUSG00000038244
AA Change: E442V
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:FAD_binding_3
|
86 |
143 |
1.1e-8 |
PFAM |
|
Pfam:FAD_binding_2
|
88 |
127 |
1.5e-6 |
PFAM |
|
Pfam:Pyr_redox_2
|
88 |
259 |
1.3e-6 |
PFAM |
|
low complexity region
|
500 |
515 |
N/A |
INTRINSIC |
|
CH
|
518 |
617 |
4.14e-17 |
SMART |
|
low complexity region
|
691 |
700 |
N/A |
INTRINSIC |
|
LIM
|
752 |
806 |
9.91e-10 |
SMART |
|
low complexity region
|
918 |
926 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
99% (79/80) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a monooxygenase that enhances depolymerization of F-actin and is therefore involved in cytoskeletal dynamics. The encoded protein is a regulator of the SRF signaling pathway. Increased expression of this gene has been associated with cancer progression and metastasis. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Arfgef3 |
A |
T |
10: 18,522,007 (GRCm39) |
I673K |
probably benign |
Het |
| Arhgap32 |
C |
A |
9: 32,093,235 (GRCm39) |
T196K |
probably benign |
Het |
| Azi2 |
T |
A |
9: 117,879,960 (GRCm39) |
|
probably null |
Het |
| B3gnt2 |
A |
T |
11: 22,786,482 (GRCm39) |
C235* |
probably null |
Het |
| Capn5 |
C |
T |
7: 97,780,426 (GRCm39) |
V315M |
probably benign |
Het |
| Ccl24 |
T |
A |
5: 135,599,676 (GRCm39) |
R111S |
possibly damaging |
Het |
| Cdk9 |
A |
G |
2: 32,602,083 (GRCm39) |
V45A |
probably damaging |
Het |
| Cep162 |
G |
T |
9: 87,130,547 (GRCm39) |
S21* |
probably null |
Het |
| Chil3 |
T |
A |
3: 106,071,496 (GRCm39) |
Y56F |
probably damaging |
Het |
| Ctr9 |
T |
A |
7: 110,642,378 (GRCm39) |
L368* |
probably null |
Het |
| Ctss |
A |
G |
3: 95,436,852 (GRCm39) |
E45G |
probably benign |
Het |
| Cyp2c29 |
A |
T |
19: 39,296,211 (GRCm39) |
Q214L |
probably null |
Het |
| Cyp2d34 |
T |
A |
15: 82,502,587 (GRCm39) |
N183I |
probably benign |
Het |
| Dhx29 |
T |
A |
13: 113,099,393 (GRCm39) |
N1139K |
probably benign |
Het |
| Elp1 |
C |
A |
4: 56,781,211 (GRCm39) |
Q487H |
possibly damaging |
Het |
| Elp1 |
T |
G |
4: 56,781,212 (GRCm39) |
Q487P |
probably benign |
Het |
| Ermp1 |
C |
A |
19: 29,604,468 (GRCm39) |
|
probably null |
Het |
| Ermp1 |
T |
A |
19: 29,604,469 (GRCm39) |
|
probably null |
Het |
| Evi2 |
A |
G |
11: 79,406,493 (GRCm39) |
S361P |
probably benign |
Het |
| Ext2 |
T |
A |
2: 93,560,612 (GRCm39) |
K518M |
probably damaging |
Het |
| Fgl1 |
A |
C |
8: 41,663,483 (GRCm39) |
M15R |
probably benign |
Het |
| Fsip2 |
T |
G |
2: 82,820,663 (GRCm39) |
D5465E |
possibly damaging |
Het |
| Hdlbp |
A |
T |
1: 93,358,783 (GRCm39) |
I256N |
possibly damaging |
Het |
| Hmmr |
G |
T |
11: 40,598,613 (GRCm39) |
|
probably null |
Het |
| Hnrnpu |
T |
C |
1: 178,164,643 (GRCm39) |
Q165R |
unknown |
Het |
| Homer3 |
G |
A |
8: 70,742,134 (GRCm39) |
A132T |
probably benign |
Het |
| Ift70a1 |
T |
C |
2: 75,810,359 (GRCm39) |
K575E |
probably benign |
Het |
| Kcnb1 |
T |
C |
2: 166,947,370 (GRCm39) |
R493G |
probably damaging |
Het |
| Kcnn3 |
A |
T |
3: 89,516,778 (GRCm39) |
T396S |
probably benign |
Het |
| Krt15 |
A |
T |
11: 100,026,386 (GRCm39) |
V100E |
possibly damaging |
Het |
| Krtap4-1 |
A |
G |
11: 99,518,810 (GRCm39) |
S67P |
unknown |
Het |
| Lama4 |
G |
T |
10: 38,963,383 (GRCm39) |
|
probably null |
Het |
| Lrrtm2 |
T |
A |
18: 35,345,818 (GRCm39) |
I495F |
possibly damaging |
Het |
| Muc16 |
C |
T |
9: 18,550,832 (GRCm39) |
V5154I |
probably benign |
Het |
| Nav3 |
A |
T |
10: 109,539,317 (GRCm39) |
M2028K |
probably benign |
Het |
| Ncr1 |
T |
A |
7: 4,347,470 (GRCm39) |
W249R |
possibly damaging |
Het |
| Neurod6 |
T |
C |
6: 55,656,616 (GRCm39) |
D7G |
probably damaging |
Het |
| Nwd1 |
A |
G |
8: 73,389,046 (GRCm39) |
E158G |
probably damaging |
Het |
| Or10ak7 |
A |
T |
4: 118,791,198 (GRCm39) |
N282K |
possibly damaging |
Het |
| Or2h15 |
A |
T |
17: 38,441,941 (GRCm39) |
F47L |
probably benign |
Het |
| Or2t26 |
A |
G |
11: 49,039,806 (GRCm39) |
T241A |
probably damaging |
Het |
| Or2y11 |
T |
C |
11: 49,443,371 (GRCm39) |
S266P |
probably damaging |
Het |
| Or51a39 |
T |
C |
7: 102,363,189 (GRCm39) |
N144D |
probably benign |
Het |
| Padi2 |
A |
G |
4: 140,665,266 (GRCm39) |
D457G |
probably benign |
Het |
| Parn |
C |
A |
16: 13,485,870 (GRCm39) |
|
probably null |
Het |
| Pcdh1 |
C |
T |
18: 38,335,838 (GRCm39) |
E266K |
possibly damaging |
Het |
| Pigr |
A |
G |
1: 130,777,303 (GRCm39) |
D703G |
probably damaging |
Het |
| Ppm1f |
T |
A |
16: 16,732,098 (GRCm39) |
S183T |
probably benign |
Het |
| Ppp2r5b |
T |
A |
19: 6,278,544 (GRCm39) |
Q455L |
probably benign |
Het |
| Pramel20 |
T |
A |
4: 143,298,876 (GRCm39) |
L273H |
probably damaging |
Het |
| Ptpn13 |
C |
T |
5: 103,688,847 (GRCm39) |
S880L |
probably damaging |
Het |
| R3hdm4 |
T |
C |
10: 79,746,943 (GRCm39) |
K240R |
probably benign |
Het |
| Rin1 |
T |
C |
19: 5,100,888 (GRCm39) |
M1T |
probably null |
Het |
| Rundc3b |
T |
A |
5: 8,609,455 (GRCm39) |
M170L |
probably benign |
Het |
| Ryr3 |
A |
T |
2: 112,611,322 (GRCm39) |
|
probably null |
Het |
| Scn11a |
T |
C |
9: 119,624,783 (GRCm39) |
D513G |
probably damaging |
Het |
| Slc27a2 |
C |
A |
2: 126,395,082 (GRCm39) |
P3Q |
unknown |
Het |
| Slc4a8 |
A |
G |
15: 100,682,743 (GRCm39) |
I187M |
probably damaging |
Het |
| Slc6a11 |
A |
T |
6: 114,215,422 (GRCm39) |
I441F |
probably benign |
Het |
| Stx2 |
C |
T |
5: 129,065,867 (GRCm39) |
R263Q |
probably damaging |
Het |
| Svep1 |
A |
T |
4: 58,145,185 (GRCm39) |
W427R |
probably damaging |
Het |
| Tes |
T |
A |
6: 17,096,166 (GRCm39) |
H51Q |
probably damaging |
Het |
| Thnsl2 |
T |
C |
6: 71,108,914 (GRCm39) |
D299G |
probably damaging |
Het |
| Tmem30b |
T |
C |
12: 73,592,702 (GRCm39) |
S138G |
probably benign |
Het |
| Tmprss11c |
T |
A |
5: 86,385,650 (GRCm39) |
H274L |
probably damaging |
Het |
| Trim10 |
G |
A |
17: 37,180,773 (GRCm39) |
M1I |
probably null |
Het |
| Unc13b |
A |
G |
4: 43,216,459 (GRCm39) |
I253V |
probably benign |
Het |
| Unc80 |
A |
G |
1: 66,734,687 (GRCm39) |
S3305G |
probably benign |
Het |
| Ush2a |
TCACC |
TC |
1: 188,694,205 (GRCm39) |
|
probably benign |
Het |
| Virma |
A |
G |
4: 11,508,099 (GRCm39) |
D267G |
probably damaging |
Het |
| Vmn1r46 |
C |
T |
6: 89,953,607 (GRCm39) |
S152L |
probably benign |
Het |
| Wdr90 |
T |
C |
17: 26,065,502 (GRCm39) |
N1621S |
probably benign |
Het |
| Zfhx3 |
G |
A |
8: 109,674,475 (GRCm39) |
A1842T |
probably damaging |
Het |
| Zfp583 |
A |
G |
7: 6,319,498 (GRCm39) |
S505P |
probably damaging |
Het |
| Zfp608 |
T |
C |
18: 55,030,619 (GRCm39) |
Y1107C |
possibly damaging |
Het |
| Zfp616 |
A |
G |
11: 73,976,155 (GRCm39) |
H808R |
probably benign |
Het |
| Zfp677 |
T |
C |
17: 21,618,653 (GRCm39) |
F570S |
possibly damaging |
Het |
| Zfp85 |
A |
T |
13: 67,897,410 (GRCm39) |
Y221N |
probably damaging |
Het |
|
| Other mutations in Mical2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Mical2
|
APN |
7 |
111,981,352 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00886:Mical2
|
APN |
7 |
111,914,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00934:Mical2
|
APN |
7 |
111,948,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00941:Mical2
|
APN |
7 |
111,920,652 (GRCm39) |
splice site |
probably benign |
|
|
IGL01020:Mical2
|
APN |
7 |
111,914,283 (GRCm39) |
splice site |
probably benign |
|
|
IGL01395:Mical2
|
APN |
7 |
111,922,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01658:Mical2
|
APN |
7 |
111,914,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01775:Mical2
|
APN |
7 |
111,981,269 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02040:Mical2
|
APN |
7 |
111,910,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02051:Mical2
|
APN |
7 |
111,980,597 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02388:Mical2
|
APN |
7 |
111,934,620 (GRCm39) |
missense |
probably benign |
|
|
IGL02551:Mical2
|
APN |
7 |
111,923,197 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02578:Mical2
|
APN |
7 |
111,950,580 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02751:Mical2
|
APN |
7 |
111,931,243 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL03114:Mical2
|
APN |
7 |
111,996,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0091:Mical2
|
UTSW |
7 |
111,980,503 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0101:Mical2
|
UTSW |
7 |
111,936,074 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0415:Mical2
|
UTSW |
7 |
111,980,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0504:Mical2
|
UTSW |
7 |
111,870,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0594:Mical2
|
UTSW |
7 |
111,917,657 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0609:Mical2
|
UTSW |
7 |
111,920,647 (GRCm39) |
splice site |
probably null |
|
|
R0962:Mical2
|
UTSW |
7 |
111,979,624 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1521:Mical2
|
UTSW |
7 |
111,980,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1542:Mical2
|
UTSW |
7 |
111,908,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1611:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1740:Mical2
|
UTSW |
7 |
111,933,043 (GRCm39) |
missense |
probably benign |
|
|
R1815:Mical2
|
UTSW |
7 |
112,012,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1855:Mical2
|
UTSW |
7 |
111,944,489 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1958:Mical2
|
UTSW |
7 |
111,980,311 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1962:Mical2
|
UTSW |
7 |
112,012,051 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2086:Mical2
|
UTSW |
7 |
111,917,810 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2136:Mical2
|
UTSW |
7 |
111,870,722 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2418:Mical2
|
UTSW |
7 |
111,919,941 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2439:Mical2
|
UTSW |
7 |
111,994,002 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3053:Mical2
|
UTSW |
7 |
111,910,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3979:Mical2
|
UTSW |
7 |
112,006,885 (GRCm39) |
splice site |
probably null |
|
|
R4308:Mical2
|
UTSW |
7 |
111,931,199 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4551:Mical2
|
UTSW |
7 |
111,981,123 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4583:Mical2
|
UTSW |
7 |
112,012,154 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4663:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4868:Mical2
|
UTSW |
7 |
111,917,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4902:Mical2
|
UTSW |
7 |
111,936,107 (GRCm39) |
missense |
probably benign |
|
|
R5112:Mical2
|
UTSW |
7 |
111,919,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5459:Mical2
|
UTSW |
7 |
111,981,444 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5487:Mical2
|
UTSW |
7 |
111,919,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5563:Mical2
|
UTSW |
7 |
111,914,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5763:Mical2
|
UTSW |
7 |
111,973,861 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5817:Mical2
|
UTSW |
7 |
111,922,866 (GRCm39) |
missense |
probably benign |
|
|
R5987:Mical2
|
UTSW |
7 |
111,934,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6042:Mical2
|
UTSW |
7 |
111,979,619 (GRCm39) |
missense |
probably benign |
0.40 |
|
R6087:Mical2
|
UTSW |
7 |
111,917,692 (GRCm39) |
nonsense |
probably null |
|
|
R6189:Mical2
|
UTSW |
7 |
112,012,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Mical2
|
UTSW |
7 |
111,923,293 (GRCm39) |
splice site |
probably null |
|
|
R6311:Mical2
|
UTSW |
7 |
111,922,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6319:Mical2
|
UTSW |
7 |
111,927,884 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6578:Mical2
|
UTSW |
7 |
111,910,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6750:Mical2
|
UTSW |
7 |
111,981,046 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6782:Mical2
|
UTSW |
7 |
111,945,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6798:Mical2
|
UTSW |
7 |
111,975,266 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R7061:Mical2
|
UTSW |
7 |
111,946,008 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7147:Mical2
|
UTSW |
7 |
111,922,810 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7260:Mical2
|
UTSW |
7 |
111,919,001 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7266:Mical2
|
UTSW |
7 |
111,902,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7347:Mical2
|
UTSW |
7 |
111,981,358 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7724:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7747:Mical2
|
UTSW |
7 |
111,933,046 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7783:Mical2
|
UTSW |
7 |
112,012,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7818:Mical2
|
UTSW |
7 |
111,944,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7824:Mical2
|
UTSW |
7 |
112,006,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7995:Mical2
|
UTSW |
7 |
111,980,975 (GRCm39) |
missense |
probably benign |
0.31 |
|
R8022:Mical2
|
UTSW |
7 |
111,902,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Mical2
|
UTSW |
7 |
111,944,460 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8505:Mical2
|
UTSW |
7 |
111,919,007 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8532:Mical2
|
UTSW |
7 |
111,917,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8830:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8862:Mical2
|
UTSW |
7 |
111,910,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8906:Mical2
|
UTSW |
7 |
111,980,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8988:Mical2
|
UTSW |
7 |
111,910,661 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9006:Mical2
|
UTSW |
7 |
111,981,323 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9123:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9127:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9128:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9129:Mical2
|
UTSW |
7 |
111,870,589 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9140:Mical2
|
UTSW |
7 |
112,006,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9187:Mical2
|
UTSW |
7 |
111,902,797 (GRCm39) |
nonsense |
probably null |
|
|
R9233:Mical2
|
UTSW |
7 |
111,981,399 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9304:Mical2
|
UTSW |
7 |
111,980,974 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9310:Mical2
|
UTSW |
7 |
111,950,920 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9377:Mical2
|
UTSW |
7 |
111,981,246 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9399:Mical2
|
UTSW |
7 |
111,946,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Mical2
|
UTSW |
7 |
112,010,665 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9500:Mical2
|
UTSW |
7 |
111,936,054 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9620:Mical2
|
UTSW |
7 |
111,980,403 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9652:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Mical2
|
UTSW |
7 |
111,921,806 (GRCm39) |
missense |
probably benign |
0.37 |
|
R9756:Mical2
|
UTSW |
7 |
111,902,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9789:Mical2
|
UTSW |
7 |
111,945,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF008:Mical2
|
UTSW |
7 |
111,922,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0062:Mical2
|
UTSW |
7 |
111,946,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCACATGGATGCTTTGCCTC -3'
(R):5'- GCCTCAGTTCCAGGAATGTG -3'
Sequencing Primer
(F):5'- ACATGGATGCTTTGCCTCTCTCC -3'
(R):5'- CCAGGAATGTGACAATTTATGAGACC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation