Incidental Mutation 'R7392:Umodl1'
| ID |
573553 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Umodl1
|
| Ensembl Gene |
ENSMUSG00000054134 |
| Gene Name |
uromodulin-like 1 |
| Synonyms |
D17Ertd488e |
| MMRRC Submission |
045474-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7392 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
30954679-31010708 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 30982332 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Arginine
at position 412
(S412R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000067443
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066554]
[ENSMUST00000066981]
[ENSMUST00000114555]
|
| AlphaFold |
Q5DID3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066554
AA Change: S412R
PolyPhen 2
Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000067443
Gene: ENSMUSG00000054134
AA Change: S412R
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066981
AA Change: S412R
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000065470
Gene: ENSMUSG00000054134
AA Change: S412R
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
8.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
8.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
619 |
632 |
N/A |
INTRINSIC |
|
SEA
|
706 |
821 |
8.88e-2 |
SMART |
|
EGF
|
818 |
859 |
4.26e0 |
SMART |
|
ZP
|
909 |
1152 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1186 |
1208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000114555
AA Change: S412R
PolyPhen 2
Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000110202
Gene: ENSMUSG00000054134
AA Change: S412R
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
9.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
9.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.8%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610021A01Rik |
T |
A |
7: 41,626,566 (GRCm38) |
F564L |
probably damaging |
Het |
| Abcc2 |
T |
C |
19: 43,808,687 (GRCm38) |
I499T |
probably damaging |
Het |
| Adamts13 |
C |
T |
2: 26,989,324 (GRCm38) |
R630C |
probably damaging |
Het |
| Adgrv1 |
A |
T |
13: 81,560,689 (GRCm38) |
F1199I |
probably damaging |
Het |
| Agbl5 |
G |
A |
5: 30,890,771 (GRCm38) |
|
probably null |
Het |
| Anks1b |
A |
G |
10: 90,680,786 (GRCm38) |
D881G |
possibly damaging |
Het |
| Arap2 |
A |
T |
5: 62,698,385 (GRCm38) |
S569R |
possibly damaging |
Het |
| Arhgap15 |
T |
C |
2: 44,063,774 (GRCm38) |
S171P |
possibly damaging |
Het |
| Arhgef11 |
G |
A |
3: 87,717,175 (GRCm38) |
|
probably null |
Het |
| Baz1a |
C |
A |
12: 54,898,765 (GRCm38) |
L1271F |
probably damaging |
Het |
| Bdnf |
A |
C |
2: 109,723,930 (GRCm38) |
K216N |
probably benign |
Het |
| Bmp7 |
C |
T |
2: 172,870,205 (GRCm38) |
D409N |
probably damaging |
Het |
| Bnip5 |
A |
T |
17: 28,908,377 (GRCm38) |
D219E |
probably benign |
Het |
| Cacna1c |
T |
A |
6: 118,741,920 (GRCm38) |
I390F |
|
Het |
| Chd8 |
A |
G |
14: 52,232,855 (GRCm38) |
S433P |
probably benign |
Het |
| Clrn2 |
A |
G |
5: 45,463,909 (GRCm38) |
E215G |
possibly damaging |
Het |
| Col19a1 |
T |
G |
1: 24,534,034 (GRCm38) |
D219A |
unknown |
Het |
| Col2a1 |
G |
A |
15: 97,980,151 (GRCm38) |
R1036* |
probably null |
Het |
| Copg1 |
T |
A |
6: 87,890,275 (GRCm38) |
V110D |
probably benign |
Het |
| Cpd |
C |
T |
11: 76,801,779 (GRCm38) |
G744D |
probably damaging |
Het |
| Crygs |
G |
A |
16: 22,806,502 (GRCm38) |
P63L |
probably benign |
Het |
| Dcn |
A |
G |
10: 97,509,998 (GRCm38) |
D224G |
probably damaging |
Het |
| Dnah7a |
T |
C |
1: 53,501,661 (GRCm38) |
E2518G |
probably benign |
Het |
| Efcab6 |
C |
A |
15: 83,988,951 (GRCm38) |
R197L |
probably benign |
Het |
| Efr3b |
T |
A |
12: 3,969,588 (GRCm38) |
Y723F |
probably benign |
Het |
| Enam |
A |
G |
5: 88,501,664 (GRCm38) |
N344S |
probably damaging |
Het |
| Erich4 |
A |
G |
7: 25,615,676 (GRCm38) |
I58T |
possibly damaging |
Het |
| Esrp1 |
A |
G |
4: 11,338,809 (GRCm38) |
V665A |
probably benign |
Het |
| Etf1 |
G |
A |
18: 34,906,050 (GRCm38) |
T388I |
probably benign |
Het |
| Faf1 |
A |
G |
4: 109,794,843 (GRCm38) |
T244A |
probably benign |
Het |
| Fbn1 |
T |
C |
2: 125,343,924 (GRCm38) |
D1610G |
probably damaging |
Het |
| Fcgbpl1 |
C |
T |
7: 28,164,372 (GRCm38) |
T2523M |
possibly damaging |
Het |
| Frem1 |
G |
T |
4: 83,013,827 (GRCm38) |
F212L |
probably benign |
Het |
| Fuom |
T |
A |
7: 140,101,160 (GRCm38) |
D85V |
probably damaging |
Het |
| Gcfc2 |
T |
C |
6: 81,943,012 (GRCm38) |
|
probably null |
Het |
| Gpr37 |
C |
T |
6: 25,688,787 (GRCm38) |
A104T |
probably benign |
Het |
| Hsp90ab1 |
G |
C |
17: 45,569,048 (GRCm38) |
T514S |
probably benign |
Het |
| Ifnl2 |
A |
G |
7: 28,509,669 (GRCm38) |
F74L |
probably benign |
Het |
| Ipo11 |
G |
A |
13: 106,891,691 (GRCm38) |
R367* |
probably null |
Het |
| Itpr2 |
T |
C |
6: 146,359,340 (GRCm38) |
D963G |
possibly damaging |
Het |
| Krt15 |
A |
T |
11: 100,135,560 (GRCm38) |
V100E |
possibly damaging |
Het |
| Lrch3 |
T |
A |
16: 32,986,755 (GRCm38) |
L466* |
probably null |
Het |
| Lrfn5 |
A |
T |
12: 61,840,304 (GRCm38) |
T293S |
probably benign |
Het |
| Lrp5 |
A |
G |
19: 3,610,199 (GRCm38) |
I955T |
probably damaging |
Het |
| Lrrc4b |
C |
T |
7: 44,462,015 (GRCm38) |
T437M |
probably damaging |
Het |
| Man1a |
A |
G |
10: 53,919,187 (GRCm38) |
Y657H |
probably damaging |
Het |
| Mapkap1 |
G |
T |
2: 34,435,154 (GRCm38) |
R94L |
probably damaging |
Het |
| Mtmr4 |
T |
A |
11: 87,604,557 (GRCm38) |
L480Q |
probably damaging |
Het |
| Mycbp2 |
A |
T |
14: 103,243,128 (GRCm38) |
C1169S |
probably damaging |
Het |
| Mycbp2 |
T |
C |
14: 103,152,191 (GRCm38) |
I3504M |
probably damaging |
Het |
| Myo15a |
T |
C |
11: 60,505,976 (GRCm38) |
S1455P |
|
Het |
| Niban1 |
A |
G |
1: 151,696,224 (GRCm38) |
T307A |
probably damaging |
Het |
| Nid2 |
A |
G |
14: 19,768,656 (GRCm38) |
D406G |
probably benign |
Het |
| Nrip2 |
A |
G |
6: 128,404,950 (GRCm38) |
I69V |
probably benign |
Het |
| Nthl1 |
G |
A |
17: 24,638,624 (GRCm38) |
V266I |
probably benign |
Het |
| Or2ag16 |
T |
C |
7: 106,753,382 (GRCm38) |
E2G |
possibly damaging |
Het |
| Or5an6 |
G |
T |
19: 12,394,465 (GRCm38) |
L67F |
probably damaging |
Het |
| Or5b21 |
A |
G |
19: 12,862,587 (GRCm38) |
T271A |
probably benign |
Het |
| Or5g23 |
A |
C |
2: 85,608,488 (GRCm38) |
C141G |
possibly damaging |
Het |
| Or5p75-ps1 |
C |
A |
7: 108,508,084 (GRCm38) |
H9Q |
possibly damaging |
Het |
| Or8k25 |
A |
G |
2: 86,413,152 (GRCm38) |
V300A |
probably benign |
Het |
| Or8s5 |
A |
G |
15: 98,340,311 (GRCm38) |
V226A |
probably benign |
Het |
| Pcdhb1 |
A |
C |
18: 37,265,118 (GRCm38) |
S41R |
possibly damaging |
Het |
| Pdcd11 |
T |
A |
19: 47,127,997 (GRCm38) |
F1529I |
probably damaging |
Het |
| Plcd3 |
C |
A |
11: 103,101,557 (GRCm38) |
|
probably benign |
Het |
| Qdpr |
T |
C |
5: 45,439,376 (GRCm38) |
M149V |
probably benign |
Het |
| R3hcc1 |
T |
A |
14: 69,705,880 (GRCm38) |
|
probably null |
Het |
| Rasgrf2 |
T |
C |
13: 91,893,737 (GRCm38) |
Y392C |
|
Het |
| Slc8a3 |
A |
C |
12: 81,314,803 (GRCm38) |
V414G |
probably damaging |
Het |
| Slco1a6 |
A |
G |
6: 142,157,277 (GRCm38) |
S54P |
probably benign |
Het |
| Sos1 |
C |
A |
17: 80,424,200 (GRCm38) |
V624F |
probably damaging |
Het |
| Spdef |
T |
C |
17: 27,717,288 (GRCm38) |
D227G |
probably benign |
Het |
| Sptb |
G |
T |
12: 76,624,229 (GRCm38) |
Q447K |
probably damaging |
Het |
| Srsf12 |
A |
T |
4: 33,209,265 (GRCm38) |
R62W |
unknown |
Het |
| Stag3 |
T |
C |
5: 138,291,366 (GRCm38) |
L266P |
probably damaging |
Het |
| Sult2b1 |
T |
C |
7: 45,742,438 (GRCm38) |
|
probably benign |
Het |
| Taf1a |
A |
G |
1: 183,409,276 (GRCm38) |
T66A |
|
Het |
| Tfg |
A |
T |
16: 56,712,609 (GRCm38) |
|
probably null |
Het |
| Trim34b |
A |
G |
7: 104,336,397 (GRCm38) |
N413S |
probably benign |
Het |
| Txndc15 |
T |
A |
13: 55,721,586 (GRCm38) |
M184K |
probably damaging |
Het |
| Zbtb8b |
T |
A |
4: 129,432,890 (GRCm38) |
M161L |
probably benign |
Het |
| Zfp597 |
A |
T |
16: 3,866,505 (GRCm38) |
V129E |
probably benign |
Het |
| Zfp790 |
T |
C |
7: 29,828,625 (GRCm38) |
I245T |
possibly damaging |
Het |
|
| Other mutations in Umodl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00915:Umodl1
|
APN |
17 |
31,008,750 (GRCm38) |
utr 3 prime |
probably benign |
|
|
IGL01344:Umodl1
|
APN |
17 |
30,996,264 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01529:Umodl1
|
APN |
17 |
30,996,259 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL01609:Umodl1
|
APN |
17 |
30,998,826 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
IGL01625:Umodl1
|
APN |
17 |
30,996,255 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01877:Umodl1
|
APN |
17 |
30,982,320 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01977:Umodl1
|
APN |
17 |
30,973,768 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02063:Umodl1
|
APN |
17 |
30,987,914 (GRCm38) |
missense |
probably benign |
0.07 |
|
IGL02160:Umodl1
|
APN |
17 |
30,986,117 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL02252:Umodl1
|
APN |
17 |
30,994,815 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02427:Umodl1
|
APN |
17 |
30,968,441 (GRCm38) |
splice site |
probably benign |
|
|
IGL02496:Umodl1
|
APN |
17 |
30,998,654 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02633:Umodl1
|
APN |
17 |
30,989,488 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03271:Umodl1
|
APN |
17 |
30,986,499 (GRCm38) |
nonsense |
probably null |
|
|
IGL03392:Umodl1
|
APN |
17 |
30,996,355 (GRCm38) |
missense |
probably damaging |
0.98 |
|
Disquieting
|
UTSW |
17 |
30,959,155 (GRCm38) |
missense |
probably damaging |
1.00 |
|
floored
|
UTSW |
17 |
30,988,057 (GRCm38) |
nonsense |
probably null |
|
|
R7231_umodl1_507
|
UTSW |
17 |
30,986,116 (GRCm38) |
missense |
probably damaging |
1.00 |
|
surprising
|
UTSW |
17 |
30,986,465 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
unsettling
|
UTSW |
17 |
30,986,554 (GRCm38) |
nonsense |
probably null |
|
|
G1citation:Umodl1
|
UTSW |
17 |
30,986,554 (GRCm38) |
nonsense |
probably null |
|
|
PIT4468001:Umodl1
|
UTSW |
17 |
30,959,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
30,968,477 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
30,968,477 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0653:Umodl1
|
UTSW |
17 |
30,984,028 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0831:Umodl1
|
UTSW |
17 |
30,996,351 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1078:Umodl1
|
UTSW |
17 |
30,959,373 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1166:Umodl1
|
UTSW |
17 |
31,002,798 (GRCm38) |
splice site |
probably benign |
|
|
R1231:Umodl1
|
UTSW |
17 |
30,959,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1459:Umodl1
|
UTSW |
17 |
30,986,504 (GRCm38) |
missense |
probably benign |
0.05 |
|
R1459:Umodl1
|
UTSW |
17 |
30,982,258 (GRCm38) |
splice site |
probably benign |
|
|
R1510:Umodl1
|
UTSW |
17 |
30,959,229 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1654:Umodl1
|
UTSW |
17 |
30,987,968 (GRCm38) |
missense |
probably benign |
|
|
R1757:Umodl1
|
UTSW |
17 |
31,008,700 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1781:Umodl1
|
UTSW |
17 |
30,968,550 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1873:Umodl1
|
UTSW |
17 |
30,982,264 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1911:Umodl1
|
UTSW |
17 |
30,992,154 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
R1917:Umodl1
|
UTSW |
17 |
30,984,043 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1918:Umodl1
|
UTSW |
17 |
30,984,043 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2057:Umodl1
|
UTSW |
17 |
31,008,766 (GRCm38) |
critical splice donor site |
probably null |
|
|
R2058:Umodl1
|
UTSW |
17 |
31,008,766 (GRCm38) |
critical splice donor site |
probably null |
|
|
R2089:Umodl1
|
UTSW |
17 |
30,971,919 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
30,971,919 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
30,971,919 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2431:Umodl1
|
UTSW |
17 |
30,992,088 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R2903:Umodl1
|
UTSW |
17 |
30,992,173 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3032:Umodl1
|
UTSW |
17 |
30,989,528 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3956:Umodl1
|
UTSW |
17 |
31,002,863 (GRCm38) |
missense |
probably benign |
0.10 |
|
R3975:Umodl1
|
UTSW |
17 |
30,984,789 (GRCm38) |
nonsense |
probably null |
|
|
R4207:Umodl1
|
UTSW |
17 |
30,959,367 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4287:Umodl1
|
UTSW |
17 |
30,988,065 (GRCm38) |
missense |
probably benign |
0.11 |
|
R4452:Umodl1
|
UTSW |
17 |
30,994,815 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4684:Umodl1
|
UTSW |
17 |
30,998,114 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4769:Umodl1
|
UTSW |
17 |
30,984,002 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4887:Umodl1
|
UTSW |
17 |
31,008,665 (GRCm38) |
missense |
probably benign |
0.06 |
|
R4888:Umodl1
|
UTSW |
17 |
30,999,201 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4978:Umodl1
|
UTSW |
17 |
30,986,081 (GRCm38) |
missense |
probably benign |
|
|
R4993:Umodl1
|
UTSW |
17 |
30,986,485 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5241:Umodl1
|
UTSW |
17 |
30,984,092 (GRCm38) |
missense |
probably benign |
0.18 |
|
R5254:Umodl1
|
UTSW |
17 |
30,980,359 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R5454:Umodl1
|
UTSW |
17 |
30,986,465 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R5456:Umodl1
|
UTSW |
17 |
30,982,289 (GRCm38) |
missense |
probably benign |
0.04 |
|
R5754:Umodl1
|
UTSW |
17 |
30,994,787 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R6189:Umodl1
|
UTSW |
17 |
30,996,282 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R6222:Umodl1
|
UTSW |
17 |
31,002,892 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6289:Umodl1
|
UTSW |
17 |
30,982,351 (GRCm38) |
missense |
probably benign |
0.16 |
|
R6432:Umodl1
|
UTSW |
17 |
30,986,147 (GRCm38) |
missense |
probably benign |
0.38 |
|
R6478:Umodl1
|
UTSW |
17 |
30,959,155 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6702:Umodl1
|
UTSW |
17 |
30,986,299 (GRCm38) |
splice site |
probably null |
|
|
R6822:Umodl1
|
UTSW |
17 |
30,986,554 (GRCm38) |
nonsense |
probably null |
|
|
R6999:Umodl1
|
UTSW |
17 |
30,999,123 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7067:Umodl1
|
UTSW |
17 |
30,982,272 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7123:Umodl1
|
UTSW |
17 |
30,982,344 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R7219:Umodl1
|
UTSW |
17 |
30,982,262 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7231:Umodl1
|
UTSW |
17 |
30,986,116 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7234:Umodl1
|
UTSW |
17 |
30,986,621 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R7297:Umodl1
|
UTSW |
17 |
31,008,665 (GRCm38) |
missense |
probably benign |
0.06 |
|
R7401:Umodl1
|
UTSW |
17 |
30,998,148 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7461:Umodl1
|
UTSW |
17 |
30,988,057 (GRCm38) |
nonsense |
probably null |
|
|
R7594:Umodl1
|
UTSW |
17 |
30,954,805 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7613:Umodl1
|
UTSW |
17 |
30,988,057 (GRCm38) |
nonsense |
probably null |
|
|
R7763:Umodl1
|
UTSW |
17 |
30,986,456 (GRCm38) |
missense |
probably benign |
0.24 |
|
R7797:Umodl1
|
UTSW |
17 |
30,959,151 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7832:Umodl1
|
UTSW |
17 |
30,973,692 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7954:Umodl1
|
UTSW |
17 |
30,986,387 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8088:Umodl1
|
UTSW |
17 |
30,973,796 (GRCm38) |
missense |
probably benign |
0.29 |
|
R8111:Umodl1
|
UTSW |
17 |
30,971,818 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8314:Umodl1
|
UTSW |
17 |
30,984,832 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8826:Umodl1
|
UTSW |
17 |
30,983,984 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R9067:Umodl1
|
UTSW |
17 |
30,973,703 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9091:Umodl1
|
UTSW |
17 |
30,966,704 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9099:Umodl1
|
UTSW |
17 |
30,959,173 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9270:Umodl1
|
UTSW |
17 |
30,966,704 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9341:Umodl1
|
UTSW |
17 |
30,998,727 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R9343:Umodl1
|
UTSW |
17 |
30,998,727 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R9400:Umodl1
|
UTSW |
17 |
30,996,393 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9569:Umodl1
|
UTSW |
17 |
30,998,169 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9615:Umodl1
|
UTSW |
17 |
30,998,178 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R9787:Umodl1
|
UTSW |
17 |
30,959,350 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGAGCAAGTGTCAGTGTTACC -3'
(R):5'- CTTTGCCCAACCACAAGGAG -3'
Sequencing Primer
(F):5'- GAGCAAGTGTCAGTGTTACCATTCC -3'
(R):5'- GGAGCCAGATTGATGATATACACTTG -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation