Incidental Mutation 'R7395:Stag1'
| ID |
573753 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Stag1
|
| Ensembl Gene |
ENSMUSG00000037286 |
| Gene Name |
STAG1 cohesin complex component |
| Synonyms |
SA-1, Scc3 |
| MMRRC Submission |
045477-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7395 (G1)
|
| Quality Score |
216.009 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
100479762-100840597 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 100678781 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glycine
at position 234
(V234G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000116205
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041418]
[ENSMUST00000123302]
[ENSMUST00000129269]
[ENSMUST00000138405]
[ENSMUST00000146312]
[ENSMUST00000155108]
|
| AlphaFold |
Q9D3E6 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000041418
AA Change: V234G
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000040724
Gene: ENSMUSG00000037286
AA Change: V234G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
59 |
72 |
N/A |
INTRINSIC |
|
Pfam:STAG
|
157 |
276 |
1.5e-50 |
PFAM |
|
SCOP:d1qbkb_
|
279 |
850 |
4e-5 |
SMART |
|
low complexity region
|
1062 |
1081 |
N/A |
INTRINSIC |
|
low complexity region
|
1107 |
1120 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000123302
AA Change: V234G
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000117879
Gene: ENSMUSG00000037286
AA Change: V234G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
59 |
72 |
N/A |
INTRINSIC |
|
Pfam:STAG
|
157 |
276 |
2.9e-51 |
PFAM |
|
low complexity region
|
303 |
315 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000129269
AA Change: V234G
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000116205
Gene: ENSMUSG00000037286
AA Change: V234G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
59 |
72 |
N/A |
INTRINSIC |
|
Pfam:STAG
|
160 |
274 |
3.8e-41 |
PFAM |
|
SCOP:d1qbkb_
|
279 |
850 |
3e-5 |
SMART |
|
low complexity region
|
1062 |
1081 |
N/A |
INTRINSIC |
|
low complexity region
|
1107 |
1120 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000138405
AA Change: V234G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000116322
Gene: ENSMUSG00000037286
AA Change: V234G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
59 |
72 |
N/A |
INTRINSIC |
|
Pfam:STAG
|
157 |
276 |
1.5e-51 |
PFAM |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000146312
AA Change: V176G
|
| SMART Domains |
Protein: ENSMUSP00000116597
Gene: ENSMUSG00000037286
AA Change: V176G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
59 |
72 |
N/A |
INTRINSIC |
|
Pfam:STAG
|
99 |
196 |
4.2e-46 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155108
|
| SMART Domains |
Protein: ENSMUSP00000118952
Gene: ENSMUSG00000037286
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
59 |
72 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
99% (92/93) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mouse embryos homozygous for a null mutation show developmental delay and die before birth. Heterozygous animals have shorter lifespan and earlier onset of tumourigenesis. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3830403N18Rik |
G |
T |
X: 55,184,140 (GRCm39) |
|
probably null |
Het |
| 4930433I11Rik |
A |
T |
7: 40,639,102 (GRCm39) |
T13S |
probably damaging |
Het |
| Abca13 |
A |
G |
11: 9,241,658 (GRCm39) |
I1174V |
probably benign |
Het |
| Acoxl |
G |
A |
2: 127,726,336 (GRCm39) |
V237M |
probably damaging |
Het |
| Adam33 |
A |
C |
2: 130,903,089 (GRCm39) |
W52G |
probably benign |
Het |
| Adgrv1 |
T |
C |
13: 81,707,467 (GRCm39) |
H1313R |
probably damaging |
Het |
| Ap3d1 |
T |
C |
10: 80,566,716 (GRCm39) |
T89A |
probably benign |
Het |
| Armc8 |
T |
C |
9: 99,415,185 (GRCm39) |
E165G |
probably damaging |
Het |
| Atp6v1c1 |
T |
C |
15: 38,691,949 (GRCm39) |
*383Q |
probably null |
Het |
| Atp8b4 |
A |
T |
2: 126,217,614 (GRCm39) |
L634Q |
possibly damaging |
Het |
| B3glct |
A |
G |
5: 149,649,069 (GRCm39) |
|
probably null |
Het |
| Bhlhe40 |
TG |
TGG |
6: 108,641,818 (GRCm39) |
254 |
probably null |
Het |
| Bicd2 |
A |
G |
13: 49,531,706 (GRCm39) |
D316G |
possibly damaging |
Het |
| Bop1 |
A |
T |
15: 76,338,041 (GRCm39) |
S610T |
probably damaging |
Het |
| Car11 |
T |
A |
7: 45,350,745 (GRCm39) |
Y80* |
probably null |
Het |
| Ccdc121rt2 |
A |
T |
5: 112,598,035 (GRCm39) |
E194V |
possibly damaging |
Het |
| Ccdc96 |
T |
C |
5: 36,642,609 (GRCm39) |
I205T |
probably benign |
Het |
| Ces2a |
A |
G |
8: 105,466,273 (GRCm39) |
E390G |
probably benign |
Het |
| Cfap54 |
C |
A |
10: 92,720,565 (GRCm39) |
V2630L |
unknown |
Het |
| Chek2 |
G |
T |
5: 111,019,974 (GRCm39) |
|
probably null |
Het |
| Cntn3 |
C |
T |
6: 102,314,355 (GRCm39) |
|
probably null |
Het |
| Cpne3 |
A |
T |
4: 19,528,239 (GRCm39) |
D339E |
probably damaging |
Het |
| Crocc2 |
C |
T |
1: 93,143,829 (GRCm39) |
Q1403* |
probably null |
Het |
| Crppa |
A |
T |
12: 36,551,994 (GRCm39) |
I283F |
possibly damaging |
Het |
| Csnka2ip |
G |
A |
16: 64,299,803 (GRCm39) |
T187I |
|
Het |
| Ctu1 |
A |
G |
7: 43,326,019 (GRCm39) |
H226R |
possibly damaging |
Het |
| Cubn |
G |
T |
2: 13,291,875 (GRCm39) |
Q3317K |
probably damaging |
Het |
| Cyp17a1 |
A |
G |
19: 46,659,134 (GRCm39) |
L169P |
probably benign |
Het |
| Dcc |
T |
A |
18: 71,507,640 (GRCm39) |
K911* |
probably null |
Het |
| Dcun1d2 |
G |
A |
8: 13,328,675 (GRCm39) |
R75* |
probably null |
Het |
| Defb19 |
A |
T |
2: 152,421,943 (GRCm39) |
|
probably null |
Het |
| Dffb |
A |
T |
4: 154,053,570 (GRCm39) |
S257R |
probably damaging |
Het |
| Dip2c |
A |
C |
13: 9,664,413 (GRCm39) |
N942T |
probably damaging |
Het |
| Dnah3 |
T |
A |
7: 119,565,474 (GRCm39) |
I169F |
|
Het |
| Dnah3 |
T |
C |
7: 119,660,183 (GRCm39) |
M830V |
probably benign |
Het |
| Dnajc5g |
G |
A |
5: 31,269,009 (GRCm39) |
S130N |
possibly damaging |
Het |
| Dscaml1 |
C |
A |
9: 45,613,703 (GRCm39) |
Q939K |
possibly damaging |
Het |
| Evpl |
G |
C |
11: 116,117,905 (GRCm39) |
N761K |
possibly damaging |
Het |
| Fbxw8 |
A |
T |
5: 118,206,280 (GRCm39) |
I556N |
probably damaging |
Het |
| Fry |
G |
T |
5: 150,304,348 (GRCm39) |
M579I |
possibly damaging |
Het |
| Ggt7 |
A |
T |
2: 155,337,800 (GRCm39) |
M488K |
probably benign |
Het |
| Gnpnat1 |
T |
A |
14: 45,619,038 (GRCm39) |
H107L |
probably benign |
Het |
| Golga2 |
C |
A |
2: 32,195,599 (GRCm39) |
P798Q |
possibly damaging |
Het |
| Gpr35 |
G |
A |
1: 92,910,929 (GRCm39) |
A214T |
probably damaging |
Het |
| Greb1 |
A |
T |
12: 16,759,431 (GRCm39) |
|
probably null |
Het |
| Hdac10 |
G |
A |
15: 89,012,487 (GRCm39) |
T32I |
probably benign |
Het |
| Hkdc1 |
G |
A |
10: 62,221,478 (GRCm39) |
T860I |
probably damaging |
Het |
| Icam5 |
C |
A |
9: 20,946,738 (GRCm39) |
P422Q |
possibly damaging |
Het |
| Ist1 |
A |
C |
8: 110,404,159 (GRCm39) |
S238A |
probably benign |
Het |
| Lrig2 |
T |
C |
3: 104,404,836 (GRCm39) |
N91D |
probably benign |
Het |
| Mapt |
A |
C |
11: 104,218,949 (GRCm39) |
D352A |
probably damaging |
Het |
| Micall2 |
G |
A |
5: 139,702,124 (GRCm39) |
P373L |
possibly damaging |
Het |
| Mocs1 |
A |
G |
17: 49,761,585 (GRCm39) |
S560G |
possibly damaging |
Het |
| Mpo |
A |
G |
11: 87,691,950 (GRCm39) |
D461G |
probably damaging |
Het |
| Myo1a |
G |
T |
10: 127,546,309 (GRCm39) |
V271L |
probably damaging |
Het |
| Ncoa1 |
G |
A |
12: 4,345,188 (GRCm39) |
P720S |
not run |
Het |
| Ncr1 |
T |
A |
7: 4,341,150 (GRCm39) |
I47N |
probably damaging |
Het |
| Ndufb6 |
G |
A |
4: 40,277,730 (GRCm39) |
R66C |
probably damaging |
Het |
| Obox5 |
A |
T |
7: 15,492,668 (GRCm39) |
S208C |
probably damaging |
Het |
| Or10q1 |
T |
C |
19: 13,726,502 (GRCm39) |
S11P |
probably damaging |
Het |
| Or2n1d |
A |
T |
17: 38,646,755 (GRCm39) |
K236* |
probably null |
Het |
| Or5p75-ps1 |
T |
A |
7: 108,107,611 (GRCm39) |
F116Y |
unknown |
Het |
| Or7d9 |
T |
A |
9: 20,197,826 (GRCm39) |
M285K |
probably damaging |
Het |
| Padi4 |
A |
C |
4: 140,488,983 (GRCm39) |
V152G |
probably damaging |
Het |
| Pdzd7 |
A |
T |
19: 45,025,450 (GRCm39) |
D348E |
probably damaging |
Het |
| Pdzph1 |
T |
A |
17: 59,186,154 (GRCm39) |
K1212N |
possibly damaging |
Het |
| Piezo2 |
C |
T |
18: 63,160,634 (GRCm39) |
G2341R |
probably damaging |
Het |
| Plb1 |
A |
G |
5: 32,511,028 (GRCm39) |
K1298E |
probably benign |
Het |
| Prr14l |
A |
G |
5: 32,985,982 (GRCm39) |
L1171P |
probably benign |
Het |
| Rab11fip5 |
T |
C |
6: 85,318,850 (GRCm39) |
T680A |
probably benign |
Het |
| Rev1 |
A |
T |
1: 38,127,146 (GRCm39) |
N371K |
possibly damaging |
Het |
| Rsf1 |
CGGCGGCGG |
CGGCGGCGGGGGCGGCGG |
7: 97,229,133 (GRCm39) |
|
probably benign |
Het |
| Ryr2 |
A |
G |
13: 11,799,997 (GRCm39) |
C917R |
probably damaging |
Het |
| Sall1 |
A |
T |
8: 89,757,549 (GRCm39) |
S852T |
possibly damaging |
Het |
| Serpine2 |
A |
G |
1: 79,779,272 (GRCm39) |
F296L |
probably damaging |
Het |
| Slc12a6 |
A |
T |
2: 112,182,887 (GRCm39) |
N754I |
probably damaging |
Het |
| Slc39a6 |
A |
T |
18: 24,718,332 (GRCm39) |
L575Q |
probably damaging |
Het |
| Smarcc2 |
T |
A |
10: 128,321,475 (GRCm39) |
L890Q |
probably damaging |
Het |
| Smg5 |
T |
A |
3: 88,268,378 (GRCm39) |
V1006D |
probably damaging |
Het |
| Ssh2 |
T |
C |
11: 77,283,899 (GRCm39) |
V51A |
probably damaging |
Het |
| St14 |
T |
C |
9: 31,008,195 (GRCm39) |
K547E |
probably benign |
Het |
| Stag3 |
A |
T |
5: 138,280,207 (GRCm39) |
Q24L |
probably benign |
Het |
| Stra6 |
T |
C |
9: 58,048,380 (GRCm39) |
Y158H |
probably damaging |
Het |
| Tcstv1a |
A |
T |
13: 120,355,666 (GRCm39) |
|
probably null |
Het |
| Tmem196 |
G |
A |
12: 119,975,002 (GRCm39) |
C62Y |
probably damaging |
Het |
| Tmem265 |
T |
A |
7: 127,164,039 (GRCm39) |
F84L |
|
Het |
| Tph1 |
C |
T |
7: 46,306,627 (GRCm39) |
|
probably null |
Het |
| Ttn |
A |
G |
2: 76,776,834 (GRCm39) |
I1522T |
unknown |
Het |
| Ulk4 |
T |
A |
9: 121,084,178 (GRCm39) |
Q129L |
probably benign |
Het |
| Usp17la |
T |
A |
7: 104,510,792 (GRCm39) |
S466T |
probably benign |
Het |
| Vmn2r31 |
A |
T |
7: 7,387,744 (GRCm39) |
V609E |
probably damaging |
Het |
| Vmn2r52 |
C |
T |
7: 9,904,744 (GRCm39) |
C365Y |
probably benign |
Het |
| Zbtb4 |
A |
T |
11: 69,666,937 (GRCm39) |
T81S |
possibly damaging |
Het |
| Zfp605 |
A |
T |
5: 110,259,885 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Stag1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00649:Stag1
|
APN |
9 |
100,658,861 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01010:Stag1
|
APN |
9 |
100,827,986 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01012:Stag1
|
APN |
9 |
100,737,912 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL01025:Stag1
|
APN |
9 |
100,833,710 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01307:Stag1
|
APN |
9 |
100,833,841 (GRCm39) |
intron |
probably benign |
|
|
IGL02149:Stag1
|
APN |
9 |
100,769,442 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02608:Stag1
|
APN |
9 |
100,639,822 (GRCm39) |
missense |
probably null |
0.99 |
|
IGL03008:Stag1
|
APN |
9 |
100,658,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03210:Stag1
|
APN |
9 |
100,727,129 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
eto_o
|
UTSW |
9 |
100,678,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4280001:Stag1
|
UTSW |
9 |
100,824,769 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0070:Stag1
|
UTSW |
9 |
100,838,461 (GRCm39) |
missense |
probably null |
1.00 |
|
R0070:Stag1
|
UTSW |
9 |
100,838,461 (GRCm39) |
missense |
probably null |
1.00 |
|
R0349:Stag1
|
UTSW |
9 |
100,658,837 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0479:Stag1
|
UTSW |
9 |
100,810,144 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0531:Stag1
|
UTSW |
9 |
100,836,300 (GRCm39) |
makesense |
probably null |
|
|
R0962:Stag1
|
UTSW |
9 |
100,678,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0976:Stag1
|
UTSW |
9 |
100,812,069 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0976:Stag1
|
UTSW |
9 |
100,658,877 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1170:Stag1
|
UTSW |
9 |
100,770,506 (GRCm39) |
intron |
probably benign |
|
|
R1499:Stag1
|
UTSW |
9 |
100,769,426 (GRCm39) |
intron |
probably benign |
|
|
R1499:Stag1
|
UTSW |
9 |
100,737,885 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1644:Stag1
|
UTSW |
9 |
100,762,953 (GRCm39) |
intron |
probably benign |
|
|
R1747:Stag1
|
UTSW |
9 |
100,770,353 (GRCm39) |
missense |
probably benign |
|
|
R1799:Stag1
|
UTSW |
9 |
100,835,515 (GRCm39) |
splice site |
probably null |
|
|
R1807:Stag1
|
UTSW |
9 |
100,790,719 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1978:Stag1
|
UTSW |
9 |
100,770,139 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2029:Stag1
|
UTSW |
9 |
100,668,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2161:Stag1
|
UTSW |
9 |
100,771,648 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2300:Stag1
|
UTSW |
9 |
100,594,553 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2327:Stag1
|
UTSW |
9 |
100,668,666 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R2426:Stag1
|
UTSW |
9 |
100,727,169 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2448:Stag1
|
UTSW |
9 |
100,770,462 (GRCm39) |
missense |
probably benign |
0.42 |
|
R2504:Stag1
|
UTSW |
9 |
100,748,263 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3713:Stag1
|
UTSW |
9 |
100,771,671 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3835:Stag1
|
UTSW |
9 |
100,620,035 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3862:Stag1
|
UTSW |
9 |
100,826,838 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4398:Stag1
|
UTSW |
9 |
100,838,659 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4568:Stag1
|
UTSW |
9 |
100,730,722 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4651:Stag1
|
UTSW |
9 |
100,678,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4652:Stag1
|
UTSW |
9 |
100,678,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4653:Stag1
|
UTSW |
9 |
100,678,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4675:Stag1
|
UTSW |
9 |
100,730,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4709:Stag1
|
UTSW |
9 |
100,620,092 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4924:Stag1
|
UTSW |
9 |
100,678,808 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5018:Stag1
|
UTSW |
9 |
100,833,672 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5435:Stag1
|
UTSW |
9 |
100,835,603 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5460:Stag1
|
UTSW |
9 |
100,838,506 (GRCm39) |
splice site |
probably null |
|
|
R5805:Stag1
|
UTSW |
9 |
100,678,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6127:Stag1
|
UTSW |
9 |
100,833,750 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6313:Stag1
|
UTSW |
9 |
100,639,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6597:Stag1
|
UTSW |
9 |
100,769,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6807:Stag1
|
UTSW |
9 |
100,826,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7099:Stag1
|
UTSW |
9 |
100,826,879 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7167:Stag1
|
UTSW |
9 |
100,827,942 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7504:Stag1
|
UTSW |
9 |
100,770,381 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7663:Stag1
|
UTSW |
9 |
100,620,191 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7769:Stag1
|
UTSW |
9 |
100,826,880 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8245:Stag1
|
UTSW |
9 |
100,811,946 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8343:Stag1
|
UTSW |
9 |
100,639,819 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8473:Stag1
|
UTSW |
9 |
100,762,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8709:Stag1
|
UTSW |
9 |
100,772,975 (GRCm39) |
intron |
probably benign |
|
|
R8925:Stag1
|
UTSW |
9 |
100,587,298 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8927:Stag1
|
UTSW |
9 |
100,587,298 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8951:Stag1
|
UTSW |
9 |
100,762,854 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9138:Stag1
|
UTSW |
9 |
100,829,335 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9233:Stag1
|
UTSW |
9 |
100,812,024 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9246:Stag1
|
UTSW |
9 |
100,770,329 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9419:Stag1
|
UTSW |
9 |
100,811,967 (GRCm39) |
missense |
probably benign |
|
|
R9442:Stag1
|
UTSW |
9 |
100,836,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9694:Stag1
|
UTSW |
9 |
100,810,151 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9740:Stag1
|
UTSW |
9 |
100,587,288 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTGAGATTAGTCTATTCCTGTCAG -3'
(R):5'- GACCCGTATGAATTTTCTATTGTCC -3'
Sequencing Primer
(F):5'- AGATTAGTCTATTCCTGTCAGTTACC -3'
(R):5'- AACTTTCTGTGCAGCCAAGG -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation