Incidental Mutation 'R7395:Dip2c'
| ID |
573769 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dip2c
|
| Ensembl Gene |
ENSMUSG00000048264 |
| Gene Name |
disco interacting protein 2 homolog C |
| Synonyms |
2900024P20Rik |
| MMRRC Submission |
045477-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.589)
|
| Stock # |
R7395 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
9326564-9718964 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 9664413 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Threonine
at position 942
(N942T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133806
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000166299]
[ENSMUST00000169960]
[ENSMUST00000174552]
|
| AlphaFold |
E9PWR4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000166299
AA Change: N943T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000126827
Gene: ENSMUSG00000048264
AA Change: N943T
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
120 |
3.55e-43 |
SMART |
|
low complexity region
|
170 |
187 |
N/A |
INTRINSIC |
|
low complexity region
|
275 |
287 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
324 |
801 |
3.6e-23 |
PFAM |
|
Pfam:AMP-binding
|
977 |
1451 |
1.5e-72 |
PFAM |
|
low complexity region
|
1514 |
1526 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000169960
AA Change: N913T
PolyPhen 2
Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000131238
Gene: ENSMUSG00000048264
AA Change: N913T
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
176 |
3.02e-37 |
SMART |
|
low complexity region
|
226 |
243 |
N/A |
INTRINSIC |
|
low complexity region
|
331 |
343 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
380 |
637 |
5.9e-10 |
PFAM |
|
SCOP:d1lci__
|
675 |
875 |
2e-8 |
SMART |
|
Pfam:AMP-binding
|
947 |
1421 |
1.2e-56 |
PFAM |
|
low complexity region
|
1484 |
1496 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000174552
AA Change: N942T
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000133806
Gene: ENSMUSG00000048264
AA Change: N942T
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
120 |
3.55e-43 |
SMART |
|
low complexity region
|
170 |
187 |
N/A |
INTRINSIC |
|
low complexity region
|
275 |
287 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
324 |
800 |
2.7e-20 |
PFAM |
|
Pfam:AMP-binding
|
976 |
1450 |
1.3e-56 |
PFAM |
|
low complexity region
|
1513 |
1525 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
99% (92/93) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the disco-interacting protein homolog 2 family. The protein shares strong similarity with a Drosophila protein which interacts with the transcription factor disco and is expressed in the nervous system. [provided by RefSeq, Oct 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3830403N18Rik |
G |
T |
X: 55,184,140 (GRCm39) |
|
probably null |
Het |
| 4930433I11Rik |
A |
T |
7: 40,639,102 (GRCm39) |
T13S |
probably damaging |
Het |
| Abca13 |
A |
G |
11: 9,241,658 (GRCm39) |
I1174V |
probably benign |
Het |
| Acoxl |
G |
A |
2: 127,726,336 (GRCm39) |
V237M |
probably damaging |
Het |
| Adam33 |
A |
C |
2: 130,903,089 (GRCm39) |
W52G |
probably benign |
Het |
| Adgrv1 |
T |
C |
13: 81,707,467 (GRCm39) |
H1313R |
probably damaging |
Het |
| Ap3d1 |
T |
C |
10: 80,566,716 (GRCm39) |
T89A |
probably benign |
Het |
| Armc8 |
T |
C |
9: 99,415,185 (GRCm39) |
E165G |
probably damaging |
Het |
| Atp6v1c1 |
T |
C |
15: 38,691,949 (GRCm39) |
*383Q |
probably null |
Het |
| Atp8b4 |
A |
T |
2: 126,217,614 (GRCm39) |
L634Q |
possibly damaging |
Het |
| B3glct |
A |
G |
5: 149,649,069 (GRCm39) |
|
probably null |
Het |
| Bhlhe40 |
TG |
TGG |
6: 108,641,818 (GRCm39) |
254 |
probably null |
Het |
| Bicd2 |
A |
G |
13: 49,531,706 (GRCm39) |
D316G |
possibly damaging |
Het |
| Bop1 |
A |
T |
15: 76,338,041 (GRCm39) |
S610T |
probably damaging |
Het |
| Car11 |
T |
A |
7: 45,350,745 (GRCm39) |
Y80* |
probably null |
Het |
| Ccdc121rt2 |
A |
T |
5: 112,598,035 (GRCm39) |
E194V |
possibly damaging |
Het |
| Ccdc96 |
T |
C |
5: 36,642,609 (GRCm39) |
I205T |
probably benign |
Het |
| Ces2a |
A |
G |
8: 105,466,273 (GRCm39) |
E390G |
probably benign |
Het |
| Cfap54 |
C |
A |
10: 92,720,565 (GRCm39) |
V2630L |
unknown |
Het |
| Chek2 |
G |
T |
5: 111,019,974 (GRCm39) |
|
probably null |
Het |
| Cntn3 |
C |
T |
6: 102,314,355 (GRCm39) |
|
probably null |
Het |
| Cpne3 |
A |
T |
4: 19,528,239 (GRCm39) |
D339E |
probably damaging |
Het |
| Crocc2 |
C |
T |
1: 93,143,829 (GRCm39) |
Q1403* |
probably null |
Het |
| Crppa |
A |
T |
12: 36,551,994 (GRCm39) |
I283F |
possibly damaging |
Het |
| Csnka2ip |
G |
A |
16: 64,299,803 (GRCm39) |
T187I |
|
Het |
| Ctu1 |
A |
G |
7: 43,326,019 (GRCm39) |
H226R |
possibly damaging |
Het |
| Cubn |
G |
T |
2: 13,291,875 (GRCm39) |
Q3317K |
probably damaging |
Het |
| Cyp17a1 |
A |
G |
19: 46,659,134 (GRCm39) |
L169P |
probably benign |
Het |
| Dcc |
T |
A |
18: 71,507,640 (GRCm39) |
K911* |
probably null |
Het |
| Dcun1d2 |
G |
A |
8: 13,328,675 (GRCm39) |
R75* |
probably null |
Het |
| Defb19 |
A |
T |
2: 152,421,943 (GRCm39) |
|
probably null |
Het |
| Dffb |
A |
T |
4: 154,053,570 (GRCm39) |
S257R |
probably damaging |
Het |
| Dnah3 |
T |
A |
7: 119,565,474 (GRCm39) |
I169F |
|
Het |
| Dnah3 |
T |
C |
7: 119,660,183 (GRCm39) |
M830V |
probably benign |
Het |
| Dnajc5g |
G |
A |
5: 31,269,009 (GRCm39) |
S130N |
possibly damaging |
Het |
| Dscaml1 |
C |
A |
9: 45,613,703 (GRCm39) |
Q939K |
possibly damaging |
Het |
| Evpl |
G |
C |
11: 116,117,905 (GRCm39) |
N761K |
possibly damaging |
Het |
| Fbxw8 |
A |
T |
5: 118,206,280 (GRCm39) |
I556N |
probably damaging |
Het |
| Fry |
G |
T |
5: 150,304,348 (GRCm39) |
M579I |
possibly damaging |
Het |
| Ggt7 |
A |
T |
2: 155,337,800 (GRCm39) |
M488K |
probably benign |
Het |
| Gnpnat1 |
T |
A |
14: 45,619,038 (GRCm39) |
H107L |
probably benign |
Het |
| Golga2 |
C |
A |
2: 32,195,599 (GRCm39) |
P798Q |
possibly damaging |
Het |
| Gpr35 |
G |
A |
1: 92,910,929 (GRCm39) |
A214T |
probably damaging |
Het |
| Greb1 |
A |
T |
12: 16,759,431 (GRCm39) |
|
probably null |
Het |
| Hdac10 |
G |
A |
15: 89,012,487 (GRCm39) |
T32I |
probably benign |
Het |
| Hkdc1 |
G |
A |
10: 62,221,478 (GRCm39) |
T860I |
probably damaging |
Het |
| Icam5 |
C |
A |
9: 20,946,738 (GRCm39) |
P422Q |
possibly damaging |
Het |
| Ist1 |
A |
C |
8: 110,404,159 (GRCm39) |
S238A |
probably benign |
Het |
| Lrig2 |
T |
C |
3: 104,404,836 (GRCm39) |
N91D |
probably benign |
Het |
| Mapt |
A |
C |
11: 104,218,949 (GRCm39) |
D352A |
probably damaging |
Het |
| Micall2 |
G |
A |
5: 139,702,124 (GRCm39) |
P373L |
possibly damaging |
Het |
| Mocs1 |
A |
G |
17: 49,761,585 (GRCm39) |
S560G |
possibly damaging |
Het |
| Mpo |
A |
G |
11: 87,691,950 (GRCm39) |
D461G |
probably damaging |
Het |
| Myo1a |
G |
T |
10: 127,546,309 (GRCm39) |
V271L |
probably damaging |
Het |
| Ncoa1 |
G |
A |
12: 4,345,188 (GRCm39) |
P720S |
not run |
Het |
| Ncr1 |
T |
A |
7: 4,341,150 (GRCm39) |
I47N |
probably damaging |
Het |
| Ndufb6 |
G |
A |
4: 40,277,730 (GRCm39) |
R66C |
probably damaging |
Het |
| Obox5 |
A |
T |
7: 15,492,668 (GRCm39) |
S208C |
probably damaging |
Het |
| Or10q1 |
T |
C |
19: 13,726,502 (GRCm39) |
S11P |
probably damaging |
Het |
| Or2n1d |
A |
T |
17: 38,646,755 (GRCm39) |
K236* |
probably null |
Het |
| Or5p75-ps1 |
T |
A |
7: 108,107,611 (GRCm39) |
F116Y |
unknown |
Het |
| Or7d9 |
T |
A |
9: 20,197,826 (GRCm39) |
M285K |
probably damaging |
Het |
| Padi4 |
A |
C |
4: 140,488,983 (GRCm39) |
V152G |
probably damaging |
Het |
| Pdzd7 |
A |
T |
19: 45,025,450 (GRCm39) |
D348E |
probably damaging |
Het |
| Pdzph1 |
T |
A |
17: 59,186,154 (GRCm39) |
K1212N |
possibly damaging |
Het |
| Piezo2 |
C |
T |
18: 63,160,634 (GRCm39) |
G2341R |
probably damaging |
Het |
| Plb1 |
A |
G |
5: 32,511,028 (GRCm39) |
K1298E |
probably benign |
Het |
| Prr14l |
A |
G |
5: 32,985,982 (GRCm39) |
L1171P |
probably benign |
Het |
| Rab11fip5 |
T |
C |
6: 85,318,850 (GRCm39) |
T680A |
probably benign |
Het |
| Rev1 |
A |
T |
1: 38,127,146 (GRCm39) |
N371K |
possibly damaging |
Het |
| Rsf1 |
CGGCGGCGG |
CGGCGGCGGGGGCGGCGG |
7: 97,229,133 (GRCm39) |
|
probably benign |
Het |
| Ryr2 |
A |
G |
13: 11,799,997 (GRCm39) |
C917R |
probably damaging |
Het |
| Sall1 |
A |
T |
8: 89,757,549 (GRCm39) |
S852T |
possibly damaging |
Het |
| Serpine2 |
A |
G |
1: 79,779,272 (GRCm39) |
F296L |
probably damaging |
Het |
| Slc12a6 |
A |
T |
2: 112,182,887 (GRCm39) |
N754I |
probably damaging |
Het |
| Slc39a6 |
A |
T |
18: 24,718,332 (GRCm39) |
L575Q |
probably damaging |
Het |
| Smarcc2 |
T |
A |
10: 128,321,475 (GRCm39) |
L890Q |
probably damaging |
Het |
| Smg5 |
T |
A |
3: 88,268,378 (GRCm39) |
V1006D |
probably damaging |
Het |
| Ssh2 |
T |
C |
11: 77,283,899 (GRCm39) |
V51A |
probably damaging |
Het |
| St14 |
T |
C |
9: 31,008,195 (GRCm39) |
K547E |
probably benign |
Het |
| Stag1 |
T |
G |
9: 100,678,781 (GRCm39) |
V234G |
probably damaging |
Het |
| Stag3 |
A |
T |
5: 138,280,207 (GRCm39) |
Q24L |
probably benign |
Het |
| Stra6 |
T |
C |
9: 58,048,380 (GRCm39) |
Y158H |
probably damaging |
Het |
| Tcstv1a |
A |
T |
13: 120,355,666 (GRCm39) |
|
probably null |
Het |
| Tmem196 |
G |
A |
12: 119,975,002 (GRCm39) |
C62Y |
probably damaging |
Het |
| Tmem265 |
T |
A |
7: 127,164,039 (GRCm39) |
F84L |
|
Het |
| Tph1 |
C |
T |
7: 46,306,627 (GRCm39) |
|
probably null |
Het |
| Ttn |
A |
G |
2: 76,776,834 (GRCm39) |
I1522T |
unknown |
Het |
| Ulk4 |
T |
A |
9: 121,084,178 (GRCm39) |
Q129L |
probably benign |
Het |
| Usp17la |
T |
A |
7: 104,510,792 (GRCm39) |
S466T |
probably benign |
Het |
| Vmn2r31 |
A |
T |
7: 7,387,744 (GRCm39) |
V609E |
probably damaging |
Het |
| Vmn2r52 |
C |
T |
7: 9,904,744 (GRCm39) |
C365Y |
probably benign |
Het |
| Zbtb4 |
A |
T |
11: 69,666,937 (GRCm39) |
T81S |
possibly damaging |
Het |
| Zfp605 |
A |
T |
5: 110,259,885 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Dip2c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00392:Dip2c
|
APN |
13 |
9,543,144 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL00426:Dip2c
|
APN |
13 |
9,656,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00503:Dip2c
|
APN |
13 |
9,617,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00586:Dip2c
|
APN |
13 |
9,660,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01306:Dip2c
|
APN |
13 |
9,625,179 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL01580:Dip2c
|
APN |
13 |
9,687,124 (GRCm39) |
splice site |
probably null |
|
|
IGL01985:Dip2c
|
APN |
13 |
9,603,303 (GRCm39) |
splice site |
probably benign |
|
|
IGL02060:Dip2c
|
APN |
13 |
9,672,666 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02122:Dip2c
|
APN |
13 |
9,556,695 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL02170:Dip2c
|
APN |
13 |
9,656,371 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02211:Dip2c
|
APN |
13 |
9,660,883 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02755:Dip2c
|
APN |
13 |
9,600,356 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02836:Dip2c
|
APN |
13 |
9,660,826 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02935:Dip2c
|
APN |
13 |
9,712,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03032:Dip2c
|
APN |
13 |
9,601,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ANU23:Dip2c
|
UTSW |
13 |
9,625,179 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
P0038:Dip2c
|
UTSW |
13 |
9,697,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0009:Dip2c
|
UTSW |
13 |
9,671,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0268:Dip2c
|
UTSW |
13 |
9,687,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0271:Dip2c
|
UTSW |
13 |
9,665,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0306:Dip2c
|
UTSW |
13 |
9,654,635 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0415:Dip2c
|
UTSW |
13 |
9,618,325 (GRCm39) |
splice site |
probably benign |
|
|
R0519:Dip2c
|
UTSW |
13 |
9,613,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0557:Dip2c
|
UTSW |
13 |
9,603,495 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0964:Dip2c
|
UTSW |
13 |
9,618,699 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0973:Dip2c
|
UTSW |
13 |
9,626,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0973:Dip2c
|
UTSW |
13 |
9,626,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0974:Dip2c
|
UTSW |
13 |
9,626,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1101:Dip2c
|
UTSW |
13 |
9,684,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1171:Dip2c
|
UTSW |
13 |
9,543,162 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1403:Dip2c
|
UTSW |
13 |
9,603,300 (GRCm39) |
splice site |
probably null |
|
|
R1403:Dip2c
|
UTSW |
13 |
9,603,300 (GRCm39) |
splice site |
probably null |
|
|
R1432:Dip2c
|
UTSW |
13 |
9,603,340 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1481:Dip2c
|
UTSW |
13 |
9,601,902 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1588:Dip2c
|
UTSW |
13 |
9,715,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1721:Dip2c
|
UTSW |
13 |
9,709,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1726:Dip2c
|
UTSW |
13 |
9,625,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1867:Dip2c
|
UTSW |
13 |
9,671,985 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R1909:Dip2c
|
UTSW |
13 |
9,583,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2013:Dip2c
|
UTSW |
13 |
9,617,882 (GRCm39) |
nonsense |
probably null |
|
|
R2022:Dip2c
|
UTSW |
13 |
9,601,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2517:Dip2c
|
UTSW |
13 |
9,659,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3746:Dip2c
|
UTSW |
13 |
9,651,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3794:Dip2c
|
UTSW |
13 |
9,654,597 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3884:Dip2c
|
UTSW |
13 |
9,601,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4019:Dip2c
|
UTSW |
13 |
9,664,401 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4110:Dip2c
|
UTSW |
13 |
9,687,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4111:Dip2c
|
UTSW |
13 |
9,687,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4113:Dip2c
|
UTSW |
13 |
9,687,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4256:Dip2c
|
UTSW |
13 |
9,659,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4300:Dip2c
|
UTSW |
13 |
9,660,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4494:Dip2c
|
UTSW |
13 |
9,621,098 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4739:Dip2c
|
UTSW |
13 |
9,583,375 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4812:Dip2c
|
UTSW |
13 |
9,687,166 (GRCm39) |
nonsense |
probably null |
|
|
R4814:Dip2c
|
UTSW |
13 |
9,586,896 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4816:Dip2c
|
UTSW |
13 |
9,625,186 (GRCm39) |
missense |
probably benign |
0.37 |
|
R4828:Dip2c
|
UTSW |
13 |
9,610,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4915:Dip2c
|
UTSW |
13 |
9,671,905 (GRCm39) |
splice site |
probably null |
|
|
R4917:Dip2c
|
UTSW |
13 |
9,671,905 (GRCm39) |
splice site |
probably null |
|
|
R4932:Dip2c
|
UTSW |
13 |
9,674,008 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4993:Dip2c
|
UTSW |
13 |
9,625,259 (GRCm39) |
nonsense |
probably null |
|
|
R5043:Dip2c
|
UTSW |
13 |
9,601,863 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5349:Dip2c
|
UTSW |
13 |
9,672,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5744:Dip2c
|
UTSW |
13 |
9,618,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5840:Dip2c
|
UTSW |
13 |
9,556,712 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6110:Dip2c
|
UTSW |
13 |
9,673,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6160:Dip2c
|
UTSW |
13 |
9,583,290 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6161:Dip2c
|
UTSW |
13 |
9,697,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6477:Dip2c
|
UTSW |
13 |
9,673,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6522:Dip2c
|
UTSW |
13 |
9,625,264 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6603:Dip2c
|
UTSW |
13 |
9,704,624 (GRCm39) |
splice site |
probably null |
|
|
R6658:Dip2c
|
UTSW |
13 |
9,543,213 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6672:Dip2c
|
UTSW |
13 |
9,617,866 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6697:Dip2c
|
UTSW |
13 |
9,671,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6991:Dip2c
|
UTSW |
13 |
9,684,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6991:Dip2c
|
UTSW |
13 |
9,601,896 (GRCm39) |
nonsense |
probably null |
|
|
R7018:Dip2c
|
UTSW |
13 |
9,709,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7053:Dip2c
|
UTSW |
13 |
9,660,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7102:Dip2c
|
UTSW |
13 |
9,654,572 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7171:Dip2c
|
UTSW |
13 |
9,556,684 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7371:Dip2c
|
UTSW |
13 |
9,642,785 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7489:Dip2c
|
UTSW |
13 |
9,583,348 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7575:Dip2c
|
UTSW |
13 |
9,678,048 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7642:Dip2c
|
UTSW |
13 |
9,672,741 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7687:Dip2c
|
UTSW |
13 |
9,654,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7699:Dip2c
|
UTSW |
13 |
9,709,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7700:Dip2c
|
UTSW |
13 |
9,709,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7715:Dip2c
|
UTSW |
13 |
9,664,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7842:Dip2c
|
UTSW |
13 |
9,656,569 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7845:Dip2c
|
UTSW |
13 |
9,659,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8354:Dip2c
|
UTSW |
13 |
9,671,918 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8685:Dip2c
|
UTSW |
13 |
9,687,161 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8779:Dip2c
|
UTSW |
13 |
9,660,845 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8786:Dip2c
|
UTSW |
13 |
9,665,830 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8815:Dip2c
|
UTSW |
13 |
9,673,834 (GRCm39) |
nonsense |
probably null |
|
|
R8833:Dip2c
|
UTSW |
13 |
9,625,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8868:Dip2c
|
UTSW |
13 |
9,625,503 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8873:Dip2c
|
UTSW |
13 |
9,625,182 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8887:Dip2c
|
UTSW |
13 |
9,673,989 (GRCm39) |
splice site |
probably benign |
|
|
R8923:Dip2c
|
UTSW |
13 |
9,673,901 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9112:Dip2c
|
UTSW |
13 |
9,660,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9424:Dip2c
|
UTSW |
13 |
9,709,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9474:Dip2c
|
UTSW |
13 |
9,544,963 (GRCm39) |
missense |
unknown |
|
|
R9527:Dip2c
|
UTSW |
13 |
9,544,875 (GRCm39) |
missense |
unknown |
|
|
R9593:Dip2c
|
UTSW |
13 |
9,704,683 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9615:Dip2c
|
UTSW |
13 |
9,625,191 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9801:Dip2c
|
UTSW |
13 |
9,626,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCATTTTGGCCATCACAAGCTC -3'
(R):5'- GACTCAGTTAAGACTCAGGACAG -3'
Sequencing Primer
(F):5'- ATTTTGGCCATCACAAGCTCATCAG -3'
(R):5'- GTTAAGACTCAGGACAGTCACTCTG -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation