Mutagenetix > Incidental Mutation

Incidental Mutation 'R7400:Ahnak'

574137

Institutional Source

Beutler Lab

Gene Symbol

Ahnak

Ensembl Gene

ENSMUSG00000069833

Gene Name

AHNAK nucleoprotein (desmoyokin)

Synonyms

1110004P15Rik, 2310047C17Rik, DY6

MMRRC Submission

045482-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.368) question?

Stock #

R7400 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

8989284-9076919 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 9014613 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glutamic Acid at position 4420 (D4420E)

Ref Sequence

ENSEMBL: ENSMUSP00000090633 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092955] [ENSMUST00000092956]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000092955

SMART Domains

Protein: ENSMUSP00000090632
Gene: ENSMUSG00000069833

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000092956
AA Change: D4420E

PolyPhen 2 Score 0.986 (Sensitivity: 0.74; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000090633
Gene: ENSMUSG00000069833
AA Change: D4420E

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART
internal_repeat_2	163	1515	5.22e-182	PROSPERO
internal_repeat_1	224	2314	N/A	PROSPERO
internal_repeat_2	1532	3028	5.22e-182	PROSPERO
internal_repeat_1	2660	5095	N/A	PROSPERO
low complexity region	5336	5353	N/A	INTRINSIC
low complexity region	5493	5504	N/A	INTRINSIC
low complexity region	5580	5600	N/A	INTRINSIC
low complexity region	5620	5636	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.0%

Validation Efficiency

97% (69/71)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016]
PHENOTYPE: Mice homozygous for one knock-out allele exhibit decreased T cell proliferation and increased susceptibility to parasitic infection. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 71 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1300017J02Rik	T	A	9: 103,250,662 (GRCm38)	E690V	probably benign	Het
4932414N04Rik	T	C	2: 68,666,203 (GRCm38)	S118P	unknown	Het
Atp5g2	C	T	15: 102,665,112 (GRCm38)	A90T	possibly damaging	Het
Batf2	A	G	19: 6,171,508 (GRCm38)	Y116C	probably damaging	Het
Cd48	G	A	1: 171,695,925 (GRCm38)	R112H	probably benign	Het
Cdh8	A	T	8: 99,279,560 (GRCm38)	Y132N	probably damaging	Het
Cfap70	A	C	14: 20,408,267 (GRCm38)	S793A	probably benign	Het
Cmip	A	G	8: 117,257,405 (GRCm38)		probably null	Het
Cyp1a2	T	C	9: 57,681,940 (GRCm38)	N197S	probably benign	Het
Diaph1	T	C	18: 37,854,502 (GRCm38)	D1067G	probably damaging	Het
Disp2	T	C	2: 118,791,886 (GRCm38)	L1033P	probably damaging	Het
Dock6	G	T	9: 21,801,807 (GRCm38)	A1981D	possibly damaging	Het
Eci3	T	C	13: 34,959,977 (GRCm38)	D55G	probably benign	Het
Eea1	T	A	10: 95,995,570 (GRCm38)	D174E	probably benign	Het
Ehd2	T	C	7: 15,950,656 (GRCm38)	E406G	possibly damaging	Het
Erich3	A	G	3: 154,762,577 (GRCm38)	K889E		Het
Fat4	C	A	3: 38,887,924 (GRCm38)	T322K	probably damaging	Het
Fitm1	A	T	14: 55,576,769 (GRCm38)	I241F	possibly damaging	Het
Fscb	C	A	12: 64,471,617 (GRCm38)	S1025I	unknown	Het
Gm4070	T	A	7: 105,902,040 (GRCm38)	I602F	probably benign	Het
Gpsm2	T	A	3: 108,679,688 (GRCm38)	D644V	probably damaging	Het
Gucy2d	C	A	7: 98,443,640 (GRCm38)	L75M	possibly damaging	Het
Hmcn1	T	C	1: 150,674,430 (GRCm38)	I2668V	probably damaging	Het
Hoxa7	A	G	6: 52,217,053 (GRCm38)	I118T	possibly damaging	Het
Hsp90ab1	A	G	17: 45,569,284 (GRCm38)	V473A	probably benign	Het
Ica1l	T	C	1: 60,042,642 (GRCm38)		probably null	Het
Ighv1-72	A	G	12: 115,758,217 (GRCm38)	S40P	probably damaging	Het
Kif28	A	C	1: 179,700,274 (GRCm38)	W771G	probably damaging	Het
Klf13	G	C	7: 63,938,248 (GRCm38)	A100G	probably benign	Het
Klhl5	A	G	5: 65,148,590 (GRCm38)	E300G	possibly damaging	Het
Krt40	A	G	11: 99,543,143 (GRCm38)	S6P	probably benign	Het
Map3k13	C	T	16: 21,922,322 (GRCm38)	R800W	probably damaging	Het
Mef2d	T	C	3: 88,167,731 (GRCm38)	L408P	possibly damaging	Het
Mmp10	T	A	9: 7,503,300 (GRCm38)	M87K	probably damaging	Het
Mrgprd	T	A	7: 145,321,906 (GRCm38)	H171Q	probably benign	Het
Muc1	C	T	3: 89,230,646 (GRCm38)	T265I	possibly damaging	Het
Myo15b	A	G	11: 115,860,113 (GRCm38)	N570D		Het
Nfs1	T	A	2: 156,126,323 (GRCm38)	I408F	probably damaging	Het
Npdc1	G	T	2: 25,406,245 (GRCm38)	C48F	probably damaging	Het
Olfr137	A	T	17: 38,305,331 (GRCm38)	N43K	possibly damaging	Het
Olfr459	A	T	6: 41,771,744 (GRCm38)	L185H	probably damaging	Het
Olfr592	T	C	7: 103,187,380 (GRCm38)	S260P	probably damaging	Het
Olfr676	T	C	7: 105,035,210 (GRCm38)	I4T	probably benign	Het
Osbpl2	T	C	2: 180,153,321 (GRCm38)	M332T	probably benign	Het
Ostm1	T	A	10: 42,698,217 (GRCm38)	V302D	probably damaging	Het
Otof	T	C	5: 30,385,188 (GRCm38)	D672G	probably benign	Het
Plekha6	A	T	1: 133,274,024 (GRCm38)	K392*	probably null	Het
Pnpla1	A	T	17: 28,858,976 (GRCm38)	D37V	probably damaging	Het
Rasgrp1	A	G	2: 117,298,545 (GRCm38)	S198P	probably damaging	Het
Reln	A	T	5: 21,971,934 (GRCm38)	N1911K	probably damaging	Het
Ripply3	C	A	16: 94,335,900 (GRCm38)	A140E	probably benign	Het
Siglec1	A	G	2: 131,086,095 (GRCm38)	C8R	possibly damaging	Het
Slamf6	T	C	1: 171,919,793 (GRCm38)	S41P	unknown	Het
Slc15a5	A	G	6: 138,073,057 (GRCm38)	M120T	probably benign	Het
Slc25a20	T	G	9: 108,681,973 (GRCm38)	D179E	possibly damaging	Het
Sltm	T	A	9: 70,586,070 (GRCm38)	V783E	probably damaging	Het
Smc1b	C	A	15: 85,069,720 (GRCm38)	R1116L	probably damaging	Het
Smim23	A	G	11: 32,824,471 (GRCm38)	V16A	probably benign	Het
Spata20	A	G	11: 94,483,400 (GRCm38)	V348A	probably benign	Het
Spen	T	C	4: 141,473,741 (GRCm38)	D2525G	probably damaging	Het
St14	A	C	9: 31,108,275 (GRCm38)	N83K	probably benign	Het
Stab1	T	C	14: 31,157,384 (GRCm38)	N713S	probably null	Het
Syne1	A	T	10: 5,218,580 (GRCm38)	L5267H	probably benign	Het
Tenm4	T	C	7: 96,694,803 (GRCm38)	L271P	probably damaging	Het
Tfap2d	C	T	1: 19,142,926 (GRCm38)	H325Y	possibly damaging	Het
Trav23	A	G	14: 53,977,563 (GRCm38)	R78G	probably benign	Het
Ttc39c	A	T	18: 12,643,799 (GRCm38)		probably benign	Het
Unc79	A	G	12: 103,104,630 (GRCm38)	D1228G	probably damaging	Het
Vmn1r66	T	A	7: 10,274,947 (GRCm38)	H53L	probably damaging	Het
Vps13b	A	T	15: 35,378,900 (GRCm38)	L53F	probably damaging	Het
Zfp532	C	T	18: 65,638,913 (GRCm38)	T834M	possibly damaging	Het

Other mutations in Ahnak

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00467:Ahnak	APN	19	9,007,223 (GRCm38)	missense	probably damaging	0.99
IGL00509:Ahnak	APN	19	9,009,951 (GRCm38)	missense	possibly damaging	0.94
IGL00539:Ahnak	APN	19	9,007,908 (GRCm38)	missense	possibly damaging	0.50
IGL00558:Ahnak	APN	19	9,004,307 (GRCm38)	missense	possibly damaging	0.93
IGL00567:Ahnak	APN	19	9,013,383 (GRCm38)	missense	probably benign	0.24
IGL00706:Ahnak	APN	19	9,013,730 (GRCm38)	nonsense	probably null
IGL00807:Ahnak	APN	19	9,008,522 (GRCm38)	missense	possibly damaging	0.92
IGL00870:Ahnak	APN	19	9,013,698 (GRCm38)	missense	probably damaging	1.00
IGL01101:Ahnak	APN	19	9,012,887 (GRCm38)	intron	probably benign
IGL01118:Ahnak	APN	19	9,012,578 (GRCm38)	missense	probably damaging	1.00
IGL01288:Ahnak	APN	19	9,002,494 (GRCm38)	missense	possibly damaging	0.94
IGL01324:Ahnak	APN	19	9,003,032 (GRCm38)	missense	probably damaging	1.00
IGL01341:Ahnak	APN	19	9,011,703 (GRCm38)	missense	probably benign
IGL01541:Ahnak	APN	19	9,007,879 (GRCm38)	missense	possibly damaging	0.95
IGL01580:Ahnak	APN	19	9,002,839 (GRCm38)	missense	probably benign	0.02
IGL01595:Ahnak	APN	19	9,003,501 (GRCm38)	nonsense	probably null
IGL01746:Ahnak	APN	19	9,004,912 (GRCm38)	missense	possibly damaging	0.89
IGL01766:Ahnak	APN	19	9,000,118 (GRCm38)	missense	unknown
IGL01821:Ahnak	APN	19	9,012,118 (GRCm38)	missense	probably benign
IGL01913:Ahnak	APN	19	9,006,064 (GRCm38)	nonsense	probably null
IGL01934:Ahnak	APN	19	9,002,657 (GRCm38)	missense	probably damaging	1.00
IGL01940:Ahnak	APN	19	9,006,557 (GRCm38)	missense	probably benign	0.14
IGL01958:Ahnak	APN	19	9,014,909 (GRCm38)	missense	possibly damaging	0.59
IGL02145:Ahnak	APN	19	9,002,855 (GRCm38)	missense	probably benign	0.11
IGL02246:Ahnak	APN	19	9,008,268 (GRCm38)	missense	probably damaging	1.00
IGL02282:Ahnak	APN	19	9,005,987 (GRCm38)	missense	probably damaging	1.00
IGL02428:Ahnak	APN	19	9,014,833 (GRCm38)	missense	possibly damaging	0.83
IGL02442:Ahnak	APN	19	9,004,016 (GRCm38)	missense	probably damaging	1.00
IGL02474:Ahnak	APN	19	9,004,933 (GRCm38)	missense	probably benign	0.13
IGL02483:Ahnak	APN	19	9,003,308 (GRCm38)	missense	probably benign	0.01
IGL02616:Ahnak	APN	19	9,005,627 (GRCm38)	missense	probably benign	0.03
IGL02630:Ahnak	APN	19	9,012,077 (GRCm38)	missense	probably damaging	1.00
IGL02690:Ahnak	APN	19	9,012,584 (GRCm38)	nonsense	probably null
IGL02717:Ahnak	APN	19	9,002,387 (GRCm38)	missense	probably benign	0.00
IGL02721:Ahnak	APN	19	9,009,707 (GRCm38)	missense	probably benign	0.07
IGL02737:Ahnak	APN	19	9,004,593 (GRCm38)	missense	probably benign	0.17
IGL02850:Ahnak	APN	19	9,002,596 (GRCm38)	missense	probably benign	0.00
IGL03071:Ahnak	APN	19	9,011,918 (GRCm38)	missense	possibly damaging	0.63
IGL03072:Ahnak	APN	19	9,006,508 (GRCm38)	missense	probably benign	0.11
IGL03094:Ahnak	APN	19	9,003,547 (GRCm38)	missense	possibly damaging	0.64
IGL03140:Ahnak	APN	19	9,005,212 (GRCm38)	intron	probably benign
IGL03176:Ahnak	APN	19	9,002,449 (GRCm38)	missense	probably damaging	1.00
IGL03176:Ahnak	APN	19	9,008,166 (GRCm38)	missense	possibly damaging	0.56
IGL03189:Ahnak	APN	19	9,011,239 (GRCm38)	missense	possibly damaging	0.65
IGL03357:Ahnak	APN	19	9,009,325 (GRCm38)	intron	probably benign
IGL03371:Ahnak	APN	19	9,004,228 (GRCm38)	missense	possibly damaging	0.91
Eskimo	UTSW	19	9,009,574 (GRCm38)	missense	probably benign	0.31
Nanook	UTSW	19	9,003,231 (GRCm38)	missense	probably benign	0.42
Netsilik	UTSW	19	9,002,321 (GRCm38)	missense	probably benign	0.00
IGL03097:Ahnak	UTSW	19	9,002,387 (GRCm38)	missense	probably benign	0.00
PIT4403001:Ahnak	UTSW	19	9,006,176 (GRCm38)	missense	possibly damaging	0.87
R0054:Ahnak	UTSW	19	9,012,056 (GRCm38)	missense	probably damaging	1.00
R0094:Ahnak	UTSW	19	9,013,893 (GRCm38)	missense	probably benign	0.12
R0110:Ahnak	UTSW	19	9,018,232 (GRCm38)	nonsense	probably null
R0141:Ahnak	UTSW	19	9,006,680 (GRCm38)	missense	probably damaging	1.00
R0166:Ahnak	UTSW	19	9,005,725 (GRCm38)	missense	probably damaging	1.00
R0309:Ahnak	UTSW	19	9,002,495 (GRCm38)	missense	probably damaging	1.00
R0368:Ahnak	UTSW	19	9,008,350 (GRCm38)	nonsense	probably null
R0386:Ahnak	UTSW	19	9,011,144 (GRCm38)	missense	possibly damaging	0.94
R0401:Ahnak	UTSW	19	9,015,116 (GRCm38)	missense	probably benign	0.24
R0415:Ahnak	UTSW	19	9,012,871 (GRCm38)	intron	probably benign
R0463:Ahnak	UTSW	19	9,009,407 (GRCm38)	intron	probably benign
R0469:Ahnak	UTSW	19	9,018,232 (GRCm38)	nonsense	probably null
R0470:Ahnak	UTSW	19	9,008,967 (GRCm38)	missense	probably benign	0.29
R0487:Ahnak	UTSW	19	9,014,120 (GRCm38)	missense	probably damaging	0.99
R0487:Ahnak	UTSW	19	9,007,151 (GRCm38)	missense	probably benign	0.00
R0499:Ahnak	UTSW	19	9,000,264 (GRCm38)	splice site	probably benign
R0506:Ahnak	UTSW	19	9,009,128 (GRCm38)	missense	probably damaging	1.00
R0510:Ahnak	UTSW	19	9,018,232 (GRCm38)	nonsense	probably null
R0557:Ahnak	UTSW	19	9,001,944 (GRCm38)	missense	probably benign	0.10
R0570:Ahnak	UTSW	19	9,013,698 (GRCm38)	missense	probably damaging	1.00
R0610:Ahnak	UTSW	19	9,007,878 (GRCm38)	missense	probably benign	0.08
R0646:Ahnak	UTSW	19	9,013,402 (GRCm38)	nonsense	probably null
R0659:Ahnak	UTSW	19	9,015,002 (GRCm38)	missense	possibly damaging	0.60
R0791:Ahnak	UTSW	19	9,016,734 (GRCm38)	missense	probably benign	0.01
R0792:Ahnak	UTSW	19	9,016,734 (GRCm38)	missense	probably benign	0.01
R0840:Ahnak	UTSW	19	9,005,063 (GRCm38)	missense	probably damaging	1.00
R0847:Ahnak	UTSW	19	9,006,433 (GRCm38)	nonsense	probably null
R0941:Ahnak	UTSW	19	9,009,914 (GRCm38)	missense	probably damaging	1.00
R0962:Ahnak	UTSW	19	9,012,848 (GRCm38)	intron	probably benign
R1017:Ahnak	UTSW	19	9,010,543 (GRCm38)	missense	probably damaging	0.99
R1037:Ahnak	UTSW	19	9,007,618 (GRCm38)	missense	probably benign	0.27
R1085:Ahnak	UTSW	19	9,013,125 (GRCm38)	missense	possibly damaging	0.50
R1113:Ahnak	UTSW	19	9,005,620 (GRCm38)	missense	probably benign	0.29
R1140:Ahnak	UTSW	19	9,004,245 (GRCm38)	missense	probably damaging	1.00
R1158:Ahnak	UTSW	19	9,013,926 (GRCm38)	missense	probably benign	0.00
R1218:Ahnak	UTSW	19	9,015,619 (GRCm38)	missense	probably damaging	1.00
R1225:Ahnak	UTSW	19	9,002,883 (GRCm38)	missense	probably damaging	1.00
R1245:Ahnak	UTSW	19	9,004,169 (GRCm38)	missense	probably benign	0.44
R1421:Ahnak	UTSW	19	9,015,631 (GRCm38)	missense	possibly damaging	0.95
R1447:Ahnak	UTSW	19	9,007,082 (GRCm38)	missense	probably damaging	0.98
R1464:Ahnak	UTSW	19	9,004,896 (GRCm38)	missense	probably damaging	1.00
R1464:Ahnak	UTSW	19	9,004,896 (GRCm38)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	9,015,875 (GRCm38)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	9,015,875 (GRCm38)	missense	probably damaging	1.00
R1471:Ahnak	UTSW	19	9,012,932 (GRCm38)	intron	probably benign
R1507:Ahnak	UTSW	19	9,010,077 (GRCm38)	missense	probably damaging	1.00
R1521:Ahnak	UTSW	19	9,004,728 (GRCm38)	missense	probably benign	0.11
R1568:Ahnak	UTSW	19	9,002,375 (GRCm38)	missense	probably damaging	0.98
R1569:Ahnak	UTSW	19	9,004,094 (GRCm38)	missense	possibly damaging	0.78
R1616:Ahnak	UTSW	19	9,008,987 (GRCm38)	missense	possibly damaging	0.94
R1638:Ahnak	UTSW	19	9,009,449 (GRCm38)	missense	probably benign	0.01
R1680:Ahnak	UTSW	19	9,009,963 (GRCm38)	missense	probably benign	0.05
R1713:Ahnak	UTSW	19	9,011,809 (GRCm38)	missense	possibly damaging	0.95
R1722:Ahnak	UTSW	19	9,010,655 (GRCm38)	missense	probably damaging	0.99
R1771:Ahnak	UTSW	19	9,013,753 (GRCm38)	missense	probably benign	0.24
R1795:Ahnak	UTSW	19	9,002,438 (GRCm38)	missense	possibly damaging	0.79
R1823:Ahnak	UTSW	19	9,004,905 (GRCm38)	missense	probably damaging	0.99
R1842:Ahnak	UTSW	19	9,005,867 (GRCm38)	missense	probably damaging	0.99
R1854:Ahnak	UTSW	19	9,013,832 (GRCm38)	missense	possibly damaging	0.61
R1856:Ahnak	UTSW	19	9,002,048 (GRCm38)	missense	possibly damaging	0.86
R1886:Ahnak	UTSW	19	9,015,979 (GRCm38)	missense	probably damaging	0.98
R1888:Ahnak	UTSW	19	9,007,088 (GRCm38)	missense	probably damaging	1.00
R1888:Ahnak	UTSW	19	9,007,088 (GRCm38)	missense	probably damaging	1.00
R1912:Ahnak	UTSW	19	9,017,881 (GRCm38)	missense	probably damaging	1.00
R1913:Ahnak	UTSW	19	9,007,922 (GRCm38)	missense	probably damaging	0.99
R1942:Ahnak	UTSW	19	9,015,083 (GRCm38)	missense	probably damaging	0.98
R1987:Ahnak	UTSW	19	9,015,251 (GRCm38)	missense	probably damaging	1.00
R2006:Ahnak	UTSW	19	9,007,075 (GRCm38)	missense	probably damaging	1.00
R2013:Ahnak	UTSW	19	9,014,573 (GRCm38)	missense	probably damaging	0.98
R2014:Ahnak	UTSW	19	9,013,181 (GRCm38)	missense	probably damaging	0.99
R2047:Ahnak	UTSW	19	9,014,300 (GRCm38)	missense	possibly damaging	0.67
R2048:Ahnak	UTSW	19	9,007,056 (GRCm38)	missense	probably damaging	0.99
R2060:Ahnak	UTSW	19	9,008,041 (GRCm38)	missense	probably benign	0.08
R2083:Ahnak	UTSW	19	9,011,557 (GRCm38)	missense	probably damaging	1.00
R2157:Ahnak	UTSW	19	9,000,684 (GRCm38)	missense	possibly damaging	0.92
R2167:Ahnak	UTSW	19	9,011,494 (GRCm38)	nonsense	probably null
R2208:Ahnak	UTSW	19	9,017,732 (GRCm38)	missense	probably benign	0.00
R2224:Ahnak	UTSW	19	9,012,991 (GRCm38)	intron	probably benign
R2268:Ahnak	UTSW	19	9,010,574 (GRCm38)	missense	possibly damaging	0.66
R2420:Ahnak	UTSW	19	9,009,256 (GRCm38)	missense	possibly damaging	0.89
R2426:Ahnak	UTSW	19	9,002,851 (GRCm38)	missense	possibly damaging	0.81
R2910:Ahnak	UTSW	19	9,011,654 (GRCm38)	missense	probably damaging	0.99
R2911:Ahnak	UTSW	19	9,011,654 (GRCm38)	missense	probably damaging	0.99
R2981:Ahnak	UTSW	19	9,000,148 (GRCm38)	missense	probably damaging	0.97
R3151:Ahnak	UTSW	19	9,009,944 (GRCm38)	missense	probably benign	0.12
R3155:Ahnak	UTSW	19	9,010,177 (GRCm38)	missense	possibly damaging	0.49
R3422:Ahnak	UTSW	19	9,006,752 (GRCm38)	missense	probably benign	0.05
R3422:Ahnak	UTSW	19	9,005,708 (GRCm38)	missense	probably benign	0.39
R3430:Ahnak	UTSW	19	9,006,958 (GRCm38)	missense	probably benign	0.42
R3433:Ahnak	UTSW	19	9,009,994 (GRCm38)	missense	probably benign	0.01
R3711:Ahnak	UTSW	19	9,007,898 (GRCm38)	missense	probably benign
R3723:Ahnak	UTSW	19	9,016,853 (GRCm38)	missense	possibly damaging	0.79
R3775:Ahnak	UTSW	19	9,009,023 (GRCm38)	missense	possibly damaging	0.91
R3858:Ahnak	UTSW	19	9,010,859 (GRCm38)	missense	possibly damaging	0.82
R3859:Ahnak	UTSW	19	9,010,859 (GRCm38)	missense	possibly damaging	0.82
R3922:Ahnak	UTSW	19	9,006,328 (GRCm38)	missense	probably benign	0.20
R3924:Ahnak	UTSW	19	9,006,328 (GRCm38)	missense	probably benign	0.20
R3926:Ahnak	UTSW	19	9,006,328 (GRCm38)	missense	probably benign	0.20
R4026:Ahnak	UTSW	19	9,011,299 (GRCm38)	missense	probably damaging	0.97
R4051:Ahnak	UTSW	19	9,014,327 (GRCm38)	missense	probably damaging	1.00
R4209:Ahnak	UTSW	19	9,002,600 (GRCm38)	missense	probably damaging	1.00
R4234:Ahnak	UTSW	19	9,000,786 (GRCm38)	nonsense	probably null
R4237:Ahnak	UTSW	19	9,001,783 (GRCm38)	missense	probably benign	0.02
R4285:Ahnak	UTSW	19	9,016,839 (GRCm38)	nonsense	probably null
R4331:Ahnak	UTSW	19	9,015,820 (GRCm38)	missense	probably damaging	1.00
R4342:Ahnak	UTSW	19	9,012,083 (GRCm38)	missense	possibly damaging	0.79
R4430:Ahnak	UTSW	19	9,003,040 (GRCm38)	missense	probably benign	0.00
R4554:Ahnak	UTSW	19	9,014,930 (GRCm38)	missense	probably damaging	1.00
R4602:Ahnak	UTSW	19	9,010,825 (GRCm38)	missense	possibly damaging	0.66
R4612:Ahnak	UTSW	19	9,003,724 (GRCm38)	missense	probably benign	0.44
R4655:Ahnak	UTSW	19	9,008,701 (GRCm38)	missense	probably damaging	1.00
R4656:Ahnak	UTSW	19	9,004,855 (GRCm38)	missense	possibly damaging	0.80
R4700:Ahnak	UTSW	19	9,004,681 (GRCm38)	missense	probably benign	0.02
R4704:Ahnak	UTSW	19	9,012,258 (GRCm38)	intron	probably benign
R4704:Ahnak	UTSW	19	9,013,181 (GRCm38)	missense	probably damaging	0.99
R4705:Ahnak	UTSW	19	9,016,906 (GRCm38)	missense	probably benign	0.07
R4707:Ahnak	UTSW	19	9,016,735 (GRCm38)	missense	probably benign	0.03
R4732:Ahnak	UTSW	19	9,007,301 (GRCm38)	missense	probably damaging	1.00
R4733:Ahnak	UTSW	19	9,007,301 (GRCm38)	missense	probably damaging	1.00
R4778:Ahnak	UTSW	19	9,011,975 (GRCm38)	missense	possibly damaging	0.79
R4782:Ahnak	UTSW	19	9,012,499 (GRCm38)	intron	probably benign
R4832:Ahnak	UTSW	19	9,012,460 (GRCm38)	intron	probably benign
R4882:Ahnak	UTSW	19	9,005,897 (GRCm38)	missense	probably damaging	0.98
R4884:Ahnak	UTSW	19	9,012,754 (GRCm38)	intron	probably benign
R4895:Ahnak	UTSW	19	9,017,441 (GRCm38)	missense	probably benign	0.43
R4930:Ahnak	UTSW	19	9,010,967 (GRCm38)	missense	possibly damaging	0.79
R4951:Ahnak	UTSW	19	9,017,835 (GRCm38)	missense	probably damaging	1.00
R4968:Ahnak	UTSW	19	9,015,100 (GRCm38)	missense	probably damaging	1.00
R5026:Ahnak	UTSW	19	9,010,631 (GRCm38)	missense	possibly damaging	0.46
R5050:Ahnak	UTSW	19	9,012,458 (GRCm38)	intron	probably benign
R5073:Ahnak	UTSW	19	9,003,231 (GRCm38)	missense	probably benign	0.42
R5110:Ahnak	UTSW	19	9,014,759 (GRCm38)	missense	probably damaging	1.00
R5119:Ahnak	UTSW	19	9,013,644 (GRCm38)	missense	probably benign	0.00
R5128:Ahnak	UTSW	19	9,017,087 (GRCm38)	missense	probably damaging	1.00
R5139:Ahnak	UTSW	19	9,004,655 (GRCm38)	missense	probably damaging	1.00
R5150:Ahnak	UTSW	19	9,010,904 (GRCm38)	missense	possibly damaging	0.46
R5151:Ahnak	UTSW	19	9,017,569 (GRCm38)	missense	probably benign	0.03
R5165:Ahnak	UTSW	19	9,015,665 (GRCm38)	missense	possibly damaging	0.95
R5236:Ahnak	UTSW	19	9,000,684 (GRCm38)	missense	possibly damaging	0.92
R5361:Ahnak	UTSW	19	9,015,341 (GRCm38)	missense	possibly damaging	0.92
R5366:Ahnak	UTSW	19	9,016,735 (GRCm38)	missense	possibly damaging	0.65
R5387:Ahnak	UTSW	19	9,003,691 (GRCm38)	missense	probably damaging	1.00
R5396:Ahnak	UTSW	19	9,007,175 (GRCm38)	missense	probably damaging	0.99
R5583:Ahnak	UTSW	19	9,006,917 (GRCm38)	missense	probably damaging	0.99
R5587:Ahnak	UTSW	19	9,009,476 (GRCm38)	missense	possibly damaging	0.88
R5620:Ahnak	UTSW	19	9,013,094 (GRCm38)	nonsense	probably null
R5643:Ahnak	UTSW	19	9,010,657 (GRCm38)	missense	possibly damaging	0.66
R5644:Ahnak	UTSW	19	9,010,657 (GRCm38)	missense	possibly damaging	0.66
R5657:Ahnak	UTSW	19	9,014,615 (GRCm38)	missense	probably damaging	0.99
R5688:Ahnak	UTSW	19	9,002,519 (GRCm38)	missense	probably benign	0.01
R5702:Ahnak	UTSW	19	9,001,840 (GRCm38)	missense	probably damaging	1.00
R5727:Ahnak	UTSW	19	9,016,747 (GRCm38)	missense	probably damaging	0.99
R5730:Ahnak	UTSW	19	9,010,253 (GRCm38)	missense	possibly damaging	0.81
R5755:Ahnak	UTSW	19	9,001,732 (GRCm38)	missense	probably benign	0.06
R5760:Ahnak	UTSW	19	9,013,562 (GRCm38)	missense	probably damaging	1.00
R5789:Ahnak	UTSW	19	9,002,321 (GRCm38)	missense	probably benign	0.00
R5790:Ahnak	UTSW	19	9,015,248 (GRCm38)	missense	probably damaging	0.99
R5795:Ahnak	UTSW	19	9,012,382 (GRCm38)	nonsense	probably null
R5808:Ahnak	UTSW	19	9,010,235 (GRCm38)	missense	possibly damaging	0.91
R5867:Ahnak	UTSW	19	9,010,052 (GRCm38)	missense	probably damaging	0.99
R5878:Ahnak	UTSW	19	9,008,342 (GRCm38)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	9,018,211 (GRCm38)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	9,013,767 (GRCm38)	missense	possibly damaging	0.63
R5912:Ahnak	UTSW	19	9,011,903 (GRCm38)	missense	probably damaging	0.99
R5935:Ahnak	UTSW	19	9,015,182 (GRCm38)	missense	possibly damaging	0.91
R5969:Ahnak	UTSW	19	9,016,585 (GRCm38)	missense	probably damaging	1.00
R5988:Ahnak	UTSW	19	9,009,347 (GRCm38)	intron	probably benign
R6000:Ahnak	UTSW	19	9,013,111 (GRCm38)	nonsense	probably null
R6005:Ahnak	UTSW	19	9,015,161 (GRCm38)	missense	possibly damaging	0.61
R6101:Ahnak	UTSW	19	9,004,099 (GRCm38)	missense	probably benign	0.20
R6105:Ahnak	UTSW	19	9,004,099 (GRCm38)	missense	probably benign	0.20
R6116:Ahnak	UTSW	19	9,012,963 (GRCm38)	intron	probably benign
R6209:Ahnak	UTSW	19	9,012,566 (GRCm38)	missense	probably damaging	1.00
R6240:Ahnak	UTSW	19	9,013,583 (GRCm38)	missense	probably damaging	1.00
R6255:Ahnak	UTSW	19	9,008,025 (GRCm38)	missense	possibly damaging	0.95
R6263:Ahnak	UTSW	19	9,018,277 (GRCm38)	missense	probably benign	0.03
R6287:Ahnak	UTSW	19	9,015,003 (GRCm38)	missense	probably benign	0.02
R6296:Ahnak	UTSW	19	9,003,305 (GRCm38)	missense	probably damaging	0.99
R6315:Ahnak	UTSW	19	9,006,626 (GRCm38)	missense	probably damaging	0.99
R6328:Ahnak	UTSW	19	9,007,148 (GRCm38)	missense	probably benign	0.11
R6331:Ahnak	UTSW	19	9,006,625 (GRCm38)	missense	probably benign	0.18
R6355:Ahnak	UTSW	19	9,008,762 (GRCm38)	missense	probably benign	0.02
R6409:Ahnak	UTSW	19	9,009,574 (GRCm38)	missense	probably benign	0.31
R6567:Ahnak	UTSW	19	9,008,806 (GRCm38)	missense	probably benign	0.27
R6572:Ahnak	UTSW	19	9,007,976 (GRCm38)	missense	probably damaging	0.99
R6574:Ahnak	UTSW	19	9,017,047 (GRCm38)	missense	probably benign	0.04
R6590:Ahnak	UTSW	19	9,009,581 (GRCm38)	missense	probably benign	0.29
R6620:Ahnak	UTSW	19	9,015,310 (GRCm38)	missense	possibly damaging	0.95
R6690:Ahnak	UTSW	19	9,009,581 (GRCm38)	missense	probably benign	0.29
R6731:Ahnak	UTSW	19	9,011,562 (GRCm38)	missense	possibly damaging	0.85
R6756:Ahnak	UTSW	19	9,007,561 (GRCm38)	missense	possibly damaging	0.59
R6846:Ahnak	UTSW	19	9,011,857 (GRCm38)	missense	possibly damaging	0.66
R6854:Ahnak	UTSW	19	9,015,235 (GRCm38)	missense	probably damaging	1.00
R6857:Ahnak	UTSW	19	9,037,168 (GRCm38)	nonsense	probably null
R6863:Ahnak	UTSW	19	9,012,365 (GRCm38)	intron	probably benign
R6876:Ahnak	UTSW	19	9,014,120 (GRCm38)	missense	probably damaging	0.99
R6958:Ahnak	UTSW	19	9,015,215 (GRCm38)	missense	possibly damaging	0.88
R7126:Ahnak	UTSW	19	9,002,359 (GRCm38)	missense	possibly damaging	0.61
R7181:Ahnak	UTSW	19	9,013,488 (GRCm38)	missense	probably damaging	1.00
R7183:Ahnak	UTSW	19	9,017,668 (GRCm38)	missense	probably damaging	1.00
R7202:Ahnak	UTSW	19	9,017,799 (GRCm38)	missense	probably damaging	1.00
R7235:Ahnak	UTSW	19	9,012,488 (GRCm38)	missense	unknown
R7241:Ahnak	UTSW	19	9,009,031 (GRCm38)	missense	possibly damaging	0.65
R7269:Ahnak	UTSW	19	9,006,617 (GRCm38)	missense	probably damaging	1.00
R7311:Ahnak	UTSW	19	9,002,143 (GRCm38)	missense	probably benign	0.04
R7311:Ahnak	UTSW	19	9,009,827 (GRCm38)	missense	possibly damaging	0.56
R7329:Ahnak	UTSW	19	9,001,792 (GRCm38)	missense	probably damaging	0.99
R7339:Ahnak	UTSW	19	9,008,165 (GRCm38)	missense	possibly damaging	0.75
R7390:Ahnak	UTSW	19	9,003,205 (GRCm38)	missense	probably benign	0.02
R7444:Ahnak	UTSW	19	9,007,423 (GRCm38)	missense	probably benign	0.08
R7483:Ahnak	UTSW	19	9,004,822 (GRCm38)	missense	probably damaging	1.00
R7498:Ahnak	UTSW	19	9,012,019 (GRCm38)	missense	probably benign	0.14
R7521:Ahnak	UTSW	19	9,002,351 (GRCm38)	missense	possibly damaging	0.89
R7522:Ahnak	UTSW	19	9,002,322 (GRCm38)	missense	probably benign	0.01
R7552:Ahnak	UTSW	19	9,006,824 (GRCm38)	missense	probably benign	0.18
R7563:Ahnak	UTSW	19	9,011,165 (GRCm38)	missense	probably damaging	0.99
R7565:Ahnak	UTSW	19	9,016,156 (GRCm38)	missense	probably benign	0.05
R7571:Ahnak	UTSW	19	9,000,786 (GRCm38)	nonsense	probably null
R7583:Ahnak	UTSW	19	9,006,093 (GRCm38)	missense	possibly damaging	0.90
R7600:Ahnak	UTSW	19	9,004,574 (GRCm38)	missense	possibly damaging	0.89
R7771:Ahnak	UTSW	19	9,015,047 (GRCm38)	missense	probably damaging	0.99
R7787:Ahnak	UTSW	19	9,009,315 (GRCm38)	missense	unknown
R7827:Ahnak	UTSW	19	9,005,344 (GRCm38)	nonsense	probably null
R7857:Ahnak	UTSW	19	9,007,468 (GRCm38)	missense	probably damaging	0.97
R7916:Ahnak	UTSW	19	9,005,832 (GRCm38)	missense	possibly damaging	0.66
R7939:Ahnak	UTSW	19	9,014,084 (GRCm38)	nonsense	probably null
R7959:Ahnak	UTSW	19	9,010,649 (GRCm38)	missense	possibly damaging	0.46
R7962:Ahnak	UTSW	19	9,012,800 (GRCm38)	missense	unknown
R7979:Ahnak	UTSW	19	9,011,432 (GRCm38)	missense	probably damaging	1.00
R8006:Ahnak	UTSW	19	9,012,083 (GRCm38)	missense	possibly damaging	0.79
R8013:Ahnak	UTSW	19	9,009,335 (GRCm38)	missense	unknown
R8033:Ahnak	UTSW	19	9,003,710 (GRCm38)	missense	probably benign	0.10
R8124:Ahnak	UTSW	19	9,007,123 (GRCm38)	missense	probably damaging	0.99
R8125:Ahnak	UTSW	19	9,011,876 (GRCm38)	missense	possibly damaging	0.95
R8129:Ahnak	UTSW	19	9,000,100 (GRCm38)	start codon destroyed	not run
R8151:Ahnak	UTSW	19	9,004,679 (GRCm38)	missense	possibly damaging	0.59
R8190:Ahnak	UTSW	19	9,002,255 (GRCm38)	missense	probably benign	0.01
R8221:Ahnak	UTSW	19	9,010,436 (GRCm38)	nonsense	probably null
R8241:Ahnak	UTSW	19	9,007,295 (GRCm38)	missense	probably benign	0.15
R8244:Ahnak	UTSW	19	9,015,673 (GRCm38)	missense	probably benign	0.44
R8248:Ahnak	UTSW	19	9,001,946 (GRCm38)	missense	probably damaging	1.00
R8261:Ahnak	UTSW	19	9,005,453 (GRCm38)	missense	probably damaging	1.00
R8330:Ahnak	UTSW	19	9,009,662 (GRCm38)	missense	possibly damaging	0.86
R8380:Ahnak	UTSW	19	9,017,855 (GRCm38)	missense	probably benign	0.05
R8407:Ahnak	UTSW	19	9,015,673 (GRCm38)	missense	probably benign	0.44
R8409:Ahnak	UTSW	19	9,015,673 (GRCm38)	missense	probably benign	0.44
R8463:Ahnak	UTSW	19	9,008,749 (GRCm38)	missense	probably benign	0.07
R8511:Ahnak	UTSW	19	9,012,355 (GRCm38)	missense	unknown
R8528:Ahnak	UTSW	19	9,007,728 (GRCm38)	missense	probably damaging	1.00
R8549:Ahnak	UTSW	19	9,011,483 (GRCm38)	missense	probably damaging	1.00
R8674:Ahnak	UTSW	19	9,005,996 (GRCm38)	missense	probably damaging	0.98
R8716:Ahnak	UTSW	19	9,009,074 (GRCm38)	missense	probably damaging	1.00
R8722:Ahnak	UTSW	19	9,013,346 (GRCm38)	nonsense	probably null
R8751:Ahnak	UTSW	19	9,010,145 (GRCm38)	missense	probably damaging	1.00
R8752:Ahnak	UTSW	19	9,015,537 (GRCm38)	missense	probably damaging	1.00
R8783:Ahnak	UTSW	19	9,011,473 (GRCm38)	missense	probably damaging	1.00
R8844:Ahnak	UTSW	19	9,006,890 (GRCm38)	missense	probably damaging	1.00
R8859:Ahnak	UTSW	19	9,007,203 (GRCm38)	missense	probably damaging	1.00
R8882:Ahnak	UTSW	19	9,000,742 (GRCm38)	missense	probably damaging	1.00
R8907:Ahnak	UTSW	19	9,009,088 (GRCm38)	missense	probably benign	0.24
R8938:Ahnak	UTSW	19	9,011,735 (GRCm38)	missense	probably benign	0.00
R8975:Ahnak	UTSW	19	9,012,737 (GRCm38)	missense	probably damaging	1.00
R8983:Ahnak	UTSW	19	9,004,113 (GRCm38)	missense	possibly damaging	0.75
R9017:Ahnak	UTSW	19	9,010,123 (GRCm38)	missense	probably damaging	1.00
R9027:Ahnak	UTSW	19	9,007,253 (GRCm38)	missense	possibly damaging	0.94
R9081:Ahnak	UTSW	19	9,008,526 (GRCm38)	missense	possibly damaging	0.81
R9104:Ahnak	UTSW	19	9,010,347 (GRCm38)	missense	probably benign	0.01
R9112:Ahnak	UTSW	19	9,009,785 (GRCm38)	missense	probably damaging	0.98
R9145:Ahnak	UTSW	19	9,014,923 (GRCm38)	missense	probably benign	0.38
R9189:Ahnak	UTSW	19	9,010,883 (GRCm38)	missense	possibly damaging	0.92
R9221:Ahnak	UTSW	19	9,012,579 (GRCm38)	missense	probably damaging	1.00
R9261:Ahnak	UTSW	19	9,016,139 (GRCm38)	missense	possibly damaging	0.63
R9299:Ahnak	UTSW	19	9,012,460 (GRCm38)	intron	probably benign
R9325:Ahnak	UTSW	19	9,013,893 (GRCm38)	missense	probably benign	0.12
R9337:Ahnak	UTSW	19	9,012,460 (GRCm38)	intron	probably benign
R9340:Ahnak	UTSW	19	9,017,047 (GRCm38)	missense	probably benign	0.04
R9351:Ahnak	UTSW	19	9,007,868 (GRCm38)	missense	probably damaging	1.00
R9416:Ahnak	UTSW	19	9,012,902 (GRCm38)	missense	unknown
R9462:Ahnak	UTSW	19	9,003,935 (GRCm38)	missense	probably damaging	0.96
R9469:Ahnak	UTSW	19	9,010,861 (GRCm38)	missense	probably damaging	1.00
R9485:Ahnak	UTSW	19	9,002,074 (GRCm38)	missense	probably benign	0.16
R9503:Ahnak	UTSW	19	9,010,094 (GRCm38)	missense	probably damaging	1.00
R9524:Ahnak	UTSW	19	9,037,253 (GRCm38)	missense
R9534:Ahnak	UTSW	19	9,003,612 (GRCm38)	missense	probably benign	0.20
R9598:Ahnak	UTSW	19	9,003,785 (GRCm38)	missense	probably benign	0.42
R9611:Ahnak	UTSW	19	9,011,798 (GRCm38)	missense	probably damaging	0.99
R9624:Ahnak	UTSW	19	9,012,482 (GRCm38)	missense	unknown
R9649:Ahnak	UTSW	19	9,008,422 (GRCm38)	nonsense	probably null
R9683:Ahnak	UTSW	19	9,007,355 (GRCm38)	missense	possibly damaging	0.94
R9691:Ahnak	UTSW	19	9,011,726 (GRCm38)	missense	possibly damaging	0.49
R9712:Ahnak	UTSW	19	9,007,029 (GRCm38)	small deletion	probably benign
R9712:Ahnak	UTSW	19	9,007,028 (GRCm38)	small deletion	probably benign
R9713:Ahnak	UTSW	19	9,007,029 (GRCm38)	small deletion	probably benign
R9715:Ahnak	UTSW	19	9,007,029 (GRCm38)	small deletion	probably benign
R9725:Ahnak	UTSW	19	9,014,243 (GRCm38)	missense	probably damaging	1.00
R9725:Ahnak	UTSW	19	9,004,169 (GRCm38)	missense	probably benign	0.44
R9747:Ahnak	UTSW	19	9,010,177 (GRCm38)	missense	possibly damaging	0.49
R9798:Ahnak	UTSW	19	9,013,619 (GRCm38)	missense	probably damaging	0.99
RF007:Ahnak	UTSW	19	9,013,601 (GRCm38)	missense	possibly damaging	0.45
X0021:Ahnak	UTSW	19	9,013,619 (GRCm38)	missense	probably damaging	0.99
X0027:Ahnak	UTSW	19	9,012,037 (GRCm38)	missense	probably damaging	1.00
Z1088:Ahnak	UTSW	19	9,016,082 (GRCm38)	missense	probably damaging	0.99
Z1176:Ahnak	UTSW	19	9,008,856 (GRCm38)	missense	probably damaging	0.97
Z1177:Ahnak	UTSW	19	9,017,468 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AGGGCCCTAAATTTAAAATGCCTG -3'
(R):5'- TTGAACTTGGGGCCCTTCAG -3'

Sequencing Primer
(F):5'- TGCCTGATCTACACCTCAAGG -3'
(R):5'- GGGGCCCTTCAGTTTTGCATC -3'

Posted On

2019-09-13