Incidental Mutation 'R7402:Obsl1'
| ID |
574217 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Obsl1
|
| Ensembl Gene |
ENSMUSG00000026211 |
| Gene Name |
obscurin-like 1 |
| Synonyms |
|
| MMRRC Submission |
045484-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.205)
|
| Stock # |
R7402 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
75462469-75483134 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 75464348 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 1653
(T1653A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109197
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000050899]
[ENSMUST00000113567]
[ENSMUST00000113575]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000050899
|
| SMART Domains |
Protein: ENSMUSP00000057865
Gene: ENSMUSG00000051703
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF4203
|
40 |
236 |
7.2e-51 |
PFAM |
|
low complexity region
|
252 |
302 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113567
AA Change: T1653A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000109197
Gene: ENSMUSG00000026211
AA Change: T1653A
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
24 |
91 |
1.23e-12 |
SMART |
|
IGc2
|
140 |
216 |
2.33e-13 |
SMART |
|
IGc2
|
258 |
326 |
1.48e-6 |
SMART |
|
IG
|
347 |
427 |
9.49e-5 |
SMART |
|
IG
|
435 |
511 |
1.04e-1 |
SMART |
|
FN3
|
518 |
601 |
6.6e-2 |
SMART |
|
PDB:2E6Q|A
|
608 |
714 |
8e-57 |
PDB |
|
Blast:IG_like
|
622 |
711 |
3e-50 |
BLAST |
|
IG
|
723 |
804 |
3.79e-4 |
SMART |
|
IG
|
814 |
893 |
2.58e-6 |
SMART |
|
IGc2
|
911 |
977 |
1.12e-6 |
SMART |
|
IG
|
996 |
1075 |
1.27e-5 |
SMART |
|
IGc2
|
1094 |
1160 |
4.07e-4 |
SMART |
|
IGc2
|
1186 |
1252 |
9.49e-5 |
SMART |
|
IG
|
1274 |
1353 |
7.41e-7 |
SMART |
|
IG
|
1363 |
1444 |
1.15e-3 |
SMART |
|
IG
|
1454 |
1533 |
8.33e-1 |
SMART |
|
IGc2
|
1549 |
1615 |
8.72e-4 |
SMART |
|
IG
|
1633 |
1712 |
1e-3 |
SMART |
|
IG
|
1723 |
1802 |
3.82e-9 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113575
|
| SMART Domains |
Protein: ENSMUSP00000109205
Gene: ENSMUSG00000051703
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF4203
|
39 |
237 |
2.2e-59 |
PFAM |
|
low complexity region
|
252 |
302 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132252
|
| SMART Domains |
Protein: ENSMUSP00000117420
Gene: ENSMUSG00000026211
| Domain | Start | End | E-Value | Type |
|---|
|
IG_like
|
1 |
59 |
2.8e-1 |
SMART |
|
IGc2
|
85 |
151 |
9.49e-5 |
SMART |
|
IG
|
175 |
254 |
2.64e-3 |
SMART |
|
IG
|
265 |
344 |
7.41e-7 |
SMART |
|
Blast:IG
|
354 |
417 |
4e-35 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155084
|
| SMART Domains |
Protein: ENSMUSP00000114553
Gene: ENSMUSG00000026211
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1g1ca_
|
2 |
32 |
1e-3 |
SMART |
|
IGc2
|
64 |
132 |
1.48e-6 |
SMART |
|
IG
|
153 |
233 |
9.49e-5 |
SMART |
|
IG
|
241 |
317 |
1.04e-1 |
SMART |
|
FN3
|
324 |
407 |
6.6e-2 |
SMART |
|
PDB:2E6Q|A
|
414 |
520 |
4e-57 |
PDB |
|
Blast:IG_like
|
428 |
517 |
2e-50 |
BLAST |
|
IG
|
529 |
610 |
3.79e-4 |
SMART |
|
IG
|
620 |
699 |
2.58e-6 |
SMART |
|
IGc2
|
717 |
783 |
1.12e-6 |
SMART |
|
IG
|
802 |
881 |
1.27e-5 |
SMART |
|
IGc2
|
900 |
966 |
4.07e-4 |
SMART |
|
IGc2
|
992 |
1058 |
9.49e-5 |
SMART |
|
IG
|
1080 |
1159 |
7.41e-7 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc4 |
G |
T |
14: 118,943,487 (GRCm39) |
P12Q |
probably damaging |
Het |
| Acsf3 |
A |
G |
8: 123,507,163 (GRCm39) |
Y152C |
probably damaging |
Het |
| Adam22 |
T |
A |
5: 8,145,049 (GRCm39) |
Q803L |
possibly damaging |
Het |
| Adamtsl3 |
G |
A |
7: 82,227,825 (GRCm39) |
V1337I |
probably damaging |
Het |
| Adra1b |
T |
C |
11: 43,666,845 (GRCm39) |
D464G |
possibly damaging |
Het |
| Alpk3 |
T |
A |
7: 80,726,660 (GRCm39) |
I115K |
probably benign |
Het |
| Amdhd2 |
A |
G |
17: 24,380,657 (GRCm39) |
S96P |
|
Het |
| Ankib1 |
T |
G |
5: 3,819,586 (GRCm39) |
D111A |
probably benign |
Het |
| Arhgef2 |
A |
G |
3: 88,540,873 (GRCm39) |
D216G |
probably damaging |
Het |
| Astn1 |
A |
T |
1: 158,380,425 (GRCm39) |
|
probably benign |
Het |
| Atosa |
C |
A |
9: 74,913,668 (GRCm39) |
Y107* |
probably null |
Het |
| Atrn |
T |
A |
2: 130,789,520 (GRCm39) |
W328R |
probably damaging |
Het |
| Atxn7 |
A |
T |
14: 14,095,427 (GRCm38) |
H375L |
probably damaging |
Het |
| Btaf1 |
A |
T |
19: 36,980,915 (GRCm39) |
N1579Y |
probably damaging |
Het |
| Cacna1b |
A |
T |
2: 24,497,671 (GRCm39) |
L2079Q |
probably benign |
Het |
| Ccdc102a |
T |
C |
8: 95,629,981 (GRCm39) |
K520R |
probably damaging |
Het |
| Cd2ap |
T |
C |
17: 43,116,054 (GRCm39) |
H602R |
possibly damaging |
Het |
| Cdkn2aip |
A |
G |
8: 48,164,408 (GRCm39) |
V435A |
possibly damaging |
Het |
| Cenpf |
A |
T |
1: 189,391,575 (GRCm39) |
Y735* |
probably null |
Het |
| Cep350 |
T |
A |
1: 155,803,961 (GRCm39) |
I1041L |
probably benign |
Het |
| Ckap4 |
A |
G |
10: 84,363,863 (GRCm39) |
V400A |
probably damaging |
Het |
| Comp |
T |
A |
8: 70,829,854 (GRCm39) |
D359E |
probably benign |
Het |
| Coq10b |
A |
C |
1: 55,100,500 (GRCm39) |
K61N |
probably benign |
Het |
| Csmd2 |
G |
A |
4: 128,215,889 (GRCm39) |
S548N |
|
Het |
| Csmd2 |
A |
C |
4: 128,215,888 (GRCm39) |
S548R |
|
Het |
| Ctif |
A |
G |
18: 75,744,807 (GRCm39) |
I99T |
probably benign |
Het |
| Ctns |
T |
G |
11: 73,083,903 (GRCm39) |
T40P |
possibly damaging |
Het |
| Cyp11b1 |
C |
T |
15: 74,712,674 (GRCm39) |
R129H |
probably damaging |
Het |
| Cyp2c68 |
A |
T |
19: 39,729,318 (GRCm39) |
N56K |
probably benign |
Het |
| D6Wsu163e |
A |
G |
6: 126,938,968 (GRCm39) |
K401R |
probably damaging |
Het |
| Dstn |
T |
A |
2: 143,780,368 (GRCm39) |
C23S |
probably benign |
Het |
| Fam72a |
A |
T |
1: 131,466,613 (GRCm39) |
E132D |
probably damaging |
Het |
| Fam72a |
G |
T |
1: 131,466,614 (GRCm39) |
E133* |
probably null |
Het |
| Gbp8 |
T |
A |
5: 105,179,161 (GRCm39) |
I113F |
probably damaging |
Het |
| Gm3095 |
A |
T |
14: 15,170,332 (GRCm39) |
R60S |
possibly damaging |
Het |
| Gpa33 |
A |
T |
1: 165,980,263 (GRCm39) |
M109L |
probably damaging |
Het |
| Grik2 |
A |
G |
10: 49,411,493 (GRCm39) |
L215P |
probably damaging |
Het |
| Gucy2g |
A |
C |
19: 55,194,725 (GRCm39) |
F897L |
probably damaging |
Het |
| Hinfp |
A |
G |
9: 44,209,314 (GRCm39) |
L295P |
probably damaging |
Het |
| Ift122 |
T |
C |
6: 115,871,283 (GRCm39) |
V526A |
probably benign |
Het |
| Ighv5-12 |
T |
C |
12: 113,665,853 (GRCm39) |
T82A |
probably benign |
Het |
| Il18rap |
T |
A |
1: 40,564,111 (GRCm39) |
S76R |
probably benign |
Het |
| Itga6 |
A |
T |
2: 71,683,897 (GRCm39) |
N1045I |
probably benign |
Het |
| Kctd21 |
A |
T |
7: 96,996,970 (GRCm39) |
I148F |
possibly damaging |
Het |
| Kif28 |
T |
A |
1: 179,567,644 (GRCm39) |
H42L |
probably benign |
Het |
| Kmt2c |
A |
C |
5: 25,600,418 (GRCm39) |
C326W |
probably damaging |
Het |
| Knl1 |
T |
A |
2: 118,925,707 (GRCm39) |
L1912* |
probably null |
Het |
| Lrfn1 |
A |
T |
7: 28,158,947 (GRCm39) |
I289F |
probably damaging |
Het |
| Lrriq1 |
T |
C |
10: 103,057,185 (GRCm39) |
K205R |
possibly damaging |
Het |
| Mbd5 |
A |
T |
2: 49,147,566 (GRCm39) |
N592I |
probably damaging |
Het |
| Mbl2 |
A |
G |
19: 30,216,802 (GRCm39) |
N205D |
possibly damaging |
Het |
| Mcm4 |
C |
A |
16: 15,455,042 (GRCm39) |
M1I |
probably null |
Het |
| Mgat4a |
T |
A |
1: 37,493,865 (GRCm39) |
H327L |
probably damaging |
Het |
| Miox |
A |
G |
15: 89,219,206 (GRCm39) |
D16G |
probably benign |
Het |
| Mvk |
C |
A |
5: 114,594,039 (GRCm39) |
P298Q |
possibly damaging |
Het |
| Nol6 |
A |
G |
4: 41,118,699 (GRCm39) |
L726P |
probably damaging |
Het |
| Nos1 |
T |
C |
5: 118,087,880 (GRCm39) |
I1381T |
probably benign |
Het |
| Nup98 |
A |
T |
7: 101,784,144 (GRCm39) |
S1063T |
probably benign |
Het |
| Obscn |
T |
G |
11: 58,886,275 (GRCm39) |
M7862L |
unknown |
Het |
| Odr4 |
A |
G |
1: 150,262,107 (GRCm39) |
|
probably null |
Het |
| Or4c105 |
G |
T |
2: 88,647,687 (GRCm39) |
M57I |
probably damaging |
Het |
| Or8g53 |
T |
A |
9: 39,683,260 (GRCm39) |
T279S |
probably benign |
Het |
| Or8u9 |
A |
G |
2: 86,001,546 (GRCm39) |
I205T |
probably benign |
Het |
| Or9q2 |
C |
T |
19: 13,772,358 (GRCm39) |
V206I |
probably damaging |
Het |
| Pcdhb20 |
A |
G |
18: 37,638,005 (GRCm39) |
Y177C |
probably benign |
Het |
| Pcdhb3 |
A |
C |
18: 37,434,657 (GRCm39) |
I208L |
probably benign |
Het |
| Phlpp1 |
G |
T |
1: 106,317,420 (GRCm39) |
G1214W |
probably damaging |
Het |
| Ppp4r3a |
A |
T |
12: 101,025,053 (GRCm39) |
S149T |
possibly damaging |
Het |
| Pxdn |
T |
C |
12: 30,052,438 (GRCm39) |
C872R |
probably damaging |
Het |
| Rarb |
A |
G |
14: 16,548,419 (GRCm38) |
C101R |
probably damaging |
Het |
| Rcor3 |
A |
C |
1: 191,812,283 (GRCm39) |
V114G |
probably benign |
Het |
| Rnpepl1 |
A |
G |
1: 92,847,372 (GRCm39) |
Q653R |
probably benign |
Het |
| Rpap2 |
T |
A |
5: 107,768,324 (GRCm39) |
Y387* |
probably null |
Het |
| Rttn |
C |
T |
18: 89,004,035 (GRCm39) |
T343M |
possibly damaging |
Het |
| Samd11 |
T |
C |
4: 156,333,230 (GRCm39) |
T333A |
probably benign |
Het |
| Six5 |
T |
C |
7: 18,828,968 (GRCm39) |
L136P |
probably damaging |
Het |
| Slc12a5 |
T |
A |
2: 164,824,852 (GRCm39) |
M419K |
probably benign |
Het |
| Slc22a21 |
T |
C |
11: 53,851,226 (GRCm39) |
M179V |
probably benign |
Het |
| Slc35a4 |
A |
G |
18: 36,813,570 (GRCm39) |
D6G |
unknown |
Het |
| Spdye4c |
A |
T |
2: 128,434,261 (GRCm39) |
M1L |
probably benign |
Het |
| Svep1 |
A |
T |
4: 58,069,699 (GRCm39) |
C2696S |
possibly damaging |
Het |
| Tceanc2 |
T |
C |
4: 107,004,893 (GRCm39) |
N85S |
probably benign |
Het |
| Teddm2 |
G |
C |
1: 153,726,344 (GRCm39) |
L124V |
probably benign |
Het |
| Teddm2 |
A |
T |
1: 153,726,343 (GRCm39) |
L124Q |
probably damaging |
Het |
| Tgfbr1 |
T |
A |
4: 47,405,623 (GRCm39) |
W409R |
probably damaging |
Het |
| Tkt |
A |
G |
14: 30,280,755 (GRCm39) |
D62G |
probably damaging |
Het |
| Tnrc6b |
T |
A |
15: 80,768,501 (GRCm39) |
V1054D |
probably damaging |
Het |
| Trpm7 |
C |
A |
2: 126,641,126 (GRCm39) |
L1564F |
probably damaging |
Het |
| Vmn1r43 |
A |
T |
6: 89,846,803 (GRCm39) |
C228S |
probably benign |
Het |
| Vmn2r106 |
T |
C |
17: 20,487,883 (GRCm39) |
R839G |
probably damaging |
Het |
| Vmn2r5 |
G |
A |
3: 64,403,176 (GRCm39) |
T523I |
probably benign |
Het |
| Vwa3b |
C |
T |
1: 37,153,678 (GRCm39) |
Q507* |
probably null |
Het |
| Wrn |
C |
G |
8: 33,738,994 (GRCm39) |
W1278S |
probably benign |
Het |
| Zfp281 |
T |
G |
1: 136,553,190 (GRCm39) |
L56R |
probably damaging |
Het |
| Zfp407 |
G |
A |
18: 84,579,661 (GRCm39) |
T484I |
probably benign |
Het |
| Zfp451 |
T |
C |
1: 33,852,843 (GRCm39) |
T24A |
probably benign |
Het |
| Zfp607b |
T |
A |
7: 27,392,919 (GRCm39) |
F16I |
probably damaging |
Het |
| Zfp638 |
T |
A |
6: 83,905,670 (GRCm39) |
V41E |
possibly damaging |
Het |
|
| Other mutations in Obsl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Obsl1
|
APN |
1 |
75,467,518 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01111:Obsl1
|
APN |
1 |
75,473,789 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL01140:Obsl1
|
APN |
1 |
75,466,400 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02149:Obsl1
|
APN |
1 |
75,480,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02225:Obsl1
|
APN |
1 |
75,480,442 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02269:Obsl1
|
APN |
1 |
75,464,357 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02296:Obsl1
|
APN |
1 |
75,474,793 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02386:Obsl1
|
APN |
1 |
75,469,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02408:Obsl1
|
APN |
1 |
75,481,890 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02601:Obsl1
|
APN |
1 |
75,466,264 (GRCm39) |
missense |
probably benign |
|
|
IGL03053:Obsl1
|
APN |
1 |
75,469,723 (GRCm39) |
missense |
probably benign |
|
|
IGL03181:Obsl1
|
APN |
1 |
75,469,228 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03402:Obsl1
|
APN |
1 |
75,463,443 (GRCm39) |
missense |
probably benign |
0.00 |
|
Jude
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT1430001:Obsl1
|
UTSW |
1 |
75,482,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4382001:Obsl1
|
UTSW |
1 |
75,464,607 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0281:Obsl1
|
UTSW |
1 |
75,469,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1343:Obsl1
|
UTSW |
1 |
75,469,223 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1394:Obsl1
|
UTSW |
1 |
75,469,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1395:Obsl1
|
UTSW |
1 |
75,469,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1439:Obsl1
|
UTSW |
1 |
75,463,428 (GRCm39) |
nonsense |
probably null |
|
|
R1456:Obsl1
|
UTSW |
1 |
75,464,300 (GRCm39) |
nonsense |
probably null |
|
|
R1728:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1729:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1730:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1739:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1757:Obsl1
|
UTSW |
1 |
75,470,527 (GRCm39) |
missense |
probably benign |
|
|
R1762:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1783:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1784:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1785:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1851:Obsl1
|
UTSW |
1 |
75,469,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1864:Obsl1
|
UTSW |
1 |
75,469,753 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1873:Obsl1
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1875:Obsl1
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1980:Obsl1
|
UTSW |
1 |
75,482,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1985:Obsl1
|
UTSW |
1 |
75,482,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2049:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2069:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2122:Obsl1
|
UTSW |
1 |
75,470,527 (GRCm39) |
missense |
probably benign |
|
|
R2141:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2142:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2184:Obsl1
|
UTSW |
1 |
75,478,861 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2267:Obsl1
|
UTSW |
1 |
75,482,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2883:Obsl1
|
UTSW |
1 |
75,473,155 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R3079:Obsl1
|
UTSW |
1 |
75,467,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3749:Obsl1
|
UTSW |
1 |
75,474,890 (GRCm39) |
missense |
probably benign |
|
|
R4002:Obsl1
|
UTSW |
1 |
75,476,743 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4365:Obsl1
|
UTSW |
1 |
75,464,693 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4366:Obsl1
|
UTSW |
1 |
75,464,693 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4414:Obsl1
|
UTSW |
1 |
75,467,546 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4700:Obsl1
|
UTSW |
1 |
75,480,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4799:Obsl1
|
UTSW |
1 |
75,466,145 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5081:Obsl1
|
UTSW |
1 |
75,464,607 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R5389:Obsl1
|
UTSW |
1 |
75,479,905 (GRCm39) |
intron |
probably benign |
|
|
R5757:Obsl1
|
UTSW |
1 |
75,469,699 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5890:Obsl1
|
UTSW |
1 |
75,470,503 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5946:Obsl1
|
UTSW |
1 |
75,467,851 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6005:Obsl1
|
UTSW |
1 |
75,468,859 (GRCm39) |
splice site |
probably null |
|
|
R6118:Obsl1
|
UTSW |
1 |
75,468,722 (GRCm39) |
intron |
probably benign |
|
|
R6154:Obsl1
|
UTSW |
1 |
75,476,788 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6317:Obsl1
|
UTSW |
1 |
75,466,273 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6379:Obsl1
|
UTSW |
1 |
75,479,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6387:Obsl1
|
UTSW |
1 |
75,468,006 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7084:Obsl1
|
UTSW |
1 |
75,464,394 (GRCm39) |
missense |
probably benign |
|
|
R7123:Obsl1
|
UTSW |
1 |
75,466,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7202:Obsl1
|
UTSW |
1 |
75,466,360 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7291:Obsl1
|
UTSW |
1 |
75,466,161 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7305:Obsl1
|
UTSW |
1 |
75,470,590 (GRCm39) |
nonsense |
probably null |
|
|
R7366:Obsl1
|
UTSW |
1 |
75,479,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7474:Obsl1
|
UTSW |
1 |
75,474,828 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7611:Obsl1
|
UTSW |
1 |
75,482,024 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7672:Obsl1
|
UTSW |
1 |
75,469,365 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7715:Obsl1
|
UTSW |
1 |
75,478,680 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7762:Obsl1
|
UTSW |
1 |
75,480,167 (GRCm39) |
missense |
probably benign |
|
|
R8005:Obsl1
|
UTSW |
1 |
75,482,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8012:Obsl1
|
UTSW |
1 |
75,469,317 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8379:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8381:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8383:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8396:Obsl1
|
UTSW |
1 |
75,480,350 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8465:Obsl1
|
UTSW |
1 |
75,480,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8506:Obsl1
|
UTSW |
1 |
75,482,300 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8710:Obsl1
|
UTSW |
1 |
75,469,326 (GRCm39) |
missense |
probably benign |
|
|
R8877:Obsl1
|
UTSW |
1 |
75,473,167 (GRCm39) |
nonsense |
probably null |
|
|
R8903:Obsl1
|
UTSW |
1 |
75,463,917 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8913:Obsl1
|
UTSW |
1 |
75,467,892 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8924:Obsl1
|
UTSW |
1 |
75,482,841 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8955:Obsl1
|
UTSW |
1 |
75,480,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9008:Obsl1
|
UTSW |
1 |
75,482,027 (GRCm39) |
missense |
probably benign |
|
|
R9121:Obsl1
|
UTSW |
1 |
75,482,636 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9295:Obsl1
|
UTSW |
1 |
75,476,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9362:Obsl1
|
UTSW |
1 |
75,482,391 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9367:Obsl1
|
UTSW |
1 |
75,466,177 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9459:Obsl1
|
UTSW |
1 |
75,474,884 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9496:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9497:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9498:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9502:Obsl1
|
UTSW |
1 |
75,466,267 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9546:Obsl1
|
UTSW |
1 |
75,482,030 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9550:Obsl1
|
UTSW |
1 |
75,474,910 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9561:Obsl1
|
UTSW |
1 |
75,480,157 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9687:Obsl1
|
UTSW |
1 |
75,479,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V8831:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
X0061:Obsl1
|
UTSW |
1 |
75,463,412 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1176:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Obsl1
|
UTSW |
1 |
75,467,656 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
Z1177:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Obsl1
|
UTSW |
1 |
75,480,436 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TAGGCAGAACTCAGAGCTGG -3'
(R):5'- TTTAACCCACTTCTAGGGAGGGG -3'
Sequencing Primer
(F):5'- CCGGGAGACACCAGCAGTAG -3'
(R):5'- CTTCTAGGGAGGGGGCGTG -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation