Incidental Mutation 'R7402:Lrriq1'
| ID |
574280 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Lrriq1
|
| Ensembl Gene |
ENSMUSG00000019892 |
| Gene Name |
leucine-rich repeats and IQ motif containing 1 |
| Synonyms |
Gm1557, LOC380658, 4930503E15Rik |
| MMRRC Submission |
045484-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.073)
|
| Stock # |
R7402 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
102881892-103072183 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 103057185 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Arginine
at position 205
(K205R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000020043
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000020043]
[ENSMUST00000123364]
[ENSMUST00000166240]
|
| AlphaFold |
Q0P5X1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000020043
AA Change: K205R
PolyPhen 2
Score 0.869 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000020043
Gene: ENSMUSG00000019892
AA Change: K205R
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
11 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
35 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
183 |
286 |
N/A |
INTRINSIC |
|
Blast:IQ
|
290 |
312 |
1e-6 |
BLAST |
|
coiled coil region
|
314 |
390 |
N/A |
INTRINSIC |
|
low complexity region
|
550 |
559 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000123364
AA Change: K205R
PolyPhen 2
Score 0.670 (Sensitivity: 0.86; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000119783
Gene: ENSMUSG00000019892
AA Change: K205R
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
11 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
35 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
183 |
286 |
N/A |
INTRINSIC |
|
Blast:IQ
|
290 |
312 |
6e-6 |
BLAST |
|
coiled coil region
|
314 |
390 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000166240
AA Change: K205R
PolyPhen 2
Score 0.670 (Sensitivity: 0.86; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000131419
Gene: ENSMUSG00000019892
AA Change: K205R
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
11 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
35 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
183 |
286 |
N/A |
INTRINSIC |
|
IQ
|
290 |
312 |
9.78e1 |
SMART |
|
coiled coil region
|
314 |
390 |
N/A |
INTRINSIC |
|
low complexity region
|
550 |
559 |
N/A |
INTRINSIC |
|
LRR
|
873 |
894 |
2.14e1 |
SMART |
|
LRR
|
895 |
917 |
4.45e1 |
SMART |
|
LRR
|
984 |
1005 |
2.03e2 |
SMART |
|
LRR
|
1029 |
1052 |
3.65e0 |
SMART |
|
low complexity region
|
1244 |
1258 |
N/A |
INTRINSIC |
|
IQ
|
1279 |
1301 |
5.61e1 |
SMART |
|
IQ
|
1339 |
1361 |
6.7e-3 |
SMART |
|
low complexity region
|
1369 |
1394 |
N/A |
INTRINSIC |
|
low complexity region
|
1502 |
1518 |
N/A |
INTRINSIC |
|
low complexity region
|
1528 |
1543 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc4 |
G |
T |
14: 118,943,487 (GRCm39) |
P12Q |
probably damaging |
Het |
| Acsf3 |
A |
G |
8: 123,507,163 (GRCm39) |
Y152C |
probably damaging |
Het |
| Adam22 |
T |
A |
5: 8,145,049 (GRCm39) |
Q803L |
possibly damaging |
Het |
| Adamtsl3 |
G |
A |
7: 82,227,825 (GRCm39) |
V1337I |
probably damaging |
Het |
| Adra1b |
T |
C |
11: 43,666,845 (GRCm39) |
D464G |
possibly damaging |
Het |
| Alpk3 |
T |
A |
7: 80,726,660 (GRCm39) |
I115K |
probably benign |
Het |
| Amdhd2 |
A |
G |
17: 24,380,657 (GRCm39) |
S96P |
|
Het |
| Ankib1 |
T |
G |
5: 3,819,586 (GRCm39) |
D111A |
probably benign |
Het |
| Arhgef2 |
A |
G |
3: 88,540,873 (GRCm39) |
D216G |
probably damaging |
Het |
| Astn1 |
A |
T |
1: 158,380,425 (GRCm39) |
|
probably benign |
Het |
| Atosa |
C |
A |
9: 74,913,668 (GRCm39) |
Y107* |
probably null |
Het |
| Atrn |
T |
A |
2: 130,789,520 (GRCm39) |
W328R |
probably damaging |
Het |
| Atxn7 |
A |
T |
14: 14,095,427 (GRCm38) |
H375L |
probably damaging |
Het |
| Btaf1 |
A |
T |
19: 36,980,915 (GRCm39) |
N1579Y |
probably damaging |
Het |
| Cacna1b |
A |
T |
2: 24,497,671 (GRCm39) |
L2079Q |
probably benign |
Het |
| Ccdc102a |
T |
C |
8: 95,629,981 (GRCm39) |
K520R |
probably damaging |
Het |
| Cd2ap |
T |
C |
17: 43,116,054 (GRCm39) |
H602R |
possibly damaging |
Het |
| Cdkn2aip |
A |
G |
8: 48,164,408 (GRCm39) |
V435A |
possibly damaging |
Het |
| Cenpf |
A |
T |
1: 189,391,575 (GRCm39) |
Y735* |
probably null |
Het |
| Cep350 |
T |
A |
1: 155,803,961 (GRCm39) |
I1041L |
probably benign |
Het |
| Ckap4 |
A |
G |
10: 84,363,863 (GRCm39) |
V400A |
probably damaging |
Het |
| Comp |
T |
A |
8: 70,829,854 (GRCm39) |
D359E |
probably benign |
Het |
| Coq10b |
A |
C |
1: 55,100,500 (GRCm39) |
K61N |
probably benign |
Het |
| Csmd2 |
G |
A |
4: 128,215,889 (GRCm39) |
S548N |
|
Het |
| Csmd2 |
A |
C |
4: 128,215,888 (GRCm39) |
S548R |
|
Het |
| Ctif |
A |
G |
18: 75,744,807 (GRCm39) |
I99T |
probably benign |
Het |
| Ctns |
T |
G |
11: 73,083,903 (GRCm39) |
T40P |
possibly damaging |
Het |
| Cyp11b1 |
C |
T |
15: 74,712,674 (GRCm39) |
R129H |
probably damaging |
Het |
| Cyp2c68 |
A |
T |
19: 39,729,318 (GRCm39) |
N56K |
probably benign |
Het |
| D6Wsu163e |
A |
G |
6: 126,938,968 (GRCm39) |
K401R |
probably damaging |
Het |
| Dstn |
T |
A |
2: 143,780,368 (GRCm39) |
C23S |
probably benign |
Het |
| Fam72a |
A |
T |
1: 131,466,613 (GRCm39) |
E132D |
probably damaging |
Het |
| Fam72a |
G |
T |
1: 131,466,614 (GRCm39) |
E133* |
probably null |
Het |
| Gbp8 |
T |
A |
5: 105,179,161 (GRCm39) |
I113F |
probably damaging |
Het |
| Gm3095 |
A |
T |
14: 15,170,332 (GRCm39) |
R60S |
possibly damaging |
Het |
| Gpa33 |
A |
T |
1: 165,980,263 (GRCm39) |
M109L |
probably damaging |
Het |
| Grik2 |
A |
G |
10: 49,411,493 (GRCm39) |
L215P |
probably damaging |
Het |
| Gucy2g |
A |
C |
19: 55,194,725 (GRCm39) |
F897L |
probably damaging |
Het |
| Hinfp |
A |
G |
9: 44,209,314 (GRCm39) |
L295P |
probably damaging |
Het |
| Ift122 |
T |
C |
6: 115,871,283 (GRCm39) |
V526A |
probably benign |
Het |
| Ighv5-12 |
T |
C |
12: 113,665,853 (GRCm39) |
T82A |
probably benign |
Het |
| Il18rap |
T |
A |
1: 40,564,111 (GRCm39) |
S76R |
probably benign |
Het |
| Itga6 |
A |
T |
2: 71,683,897 (GRCm39) |
N1045I |
probably benign |
Het |
| Kctd21 |
A |
T |
7: 96,996,970 (GRCm39) |
I148F |
possibly damaging |
Het |
| Kif28 |
T |
A |
1: 179,567,644 (GRCm39) |
H42L |
probably benign |
Het |
| Kmt2c |
A |
C |
5: 25,600,418 (GRCm39) |
C326W |
probably damaging |
Het |
| Knl1 |
T |
A |
2: 118,925,707 (GRCm39) |
L1912* |
probably null |
Het |
| Lrfn1 |
A |
T |
7: 28,158,947 (GRCm39) |
I289F |
probably damaging |
Het |
| Mbd5 |
A |
T |
2: 49,147,566 (GRCm39) |
N592I |
probably damaging |
Het |
| Mbl2 |
A |
G |
19: 30,216,802 (GRCm39) |
N205D |
possibly damaging |
Het |
| Mcm4 |
C |
A |
16: 15,455,042 (GRCm39) |
M1I |
probably null |
Het |
| Mgat4a |
T |
A |
1: 37,493,865 (GRCm39) |
H327L |
probably damaging |
Het |
| Miox |
A |
G |
15: 89,219,206 (GRCm39) |
D16G |
probably benign |
Het |
| Mvk |
C |
A |
5: 114,594,039 (GRCm39) |
P298Q |
possibly damaging |
Het |
| Nol6 |
A |
G |
4: 41,118,699 (GRCm39) |
L726P |
probably damaging |
Het |
| Nos1 |
T |
C |
5: 118,087,880 (GRCm39) |
I1381T |
probably benign |
Het |
| Nup98 |
A |
T |
7: 101,784,144 (GRCm39) |
S1063T |
probably benign |
Het |
| Obscn |
T |
G |
11: 58,886,275 (GRCm39) |
M7862L |
unknown |
Het |
| Obsl1 |
T |
C |
1: 75,464,348 (GRCm39) |
T1653A |
probably benign |
Het |
| Odr4 |
A |
G |
1: 150,262,107 (GRCm39) |
|
probably null |
Het |
| Or4c105 |
G |
T |
2: 88,647,687 (GRCm39) |
M57I |
probably damaging |
Het |
| Or8g53 |
T |
A |
9: 39,683,260 (GRCm39) |
T279S |
probably benign |
Het |
| Or8u9 |
A |
G |
2: 86,001,546 (GRCm39) |
I205T |
probably benign |
Het |
| Or9q2 |
C |
T |
19: 13,772,358 (GRCm39) |
V206I |
probably damaging |
Het |
| Pcdhb20 |
A |
G |
18: 37,638,005 (GRCm39) |
Y177C |
probably benign |
Het |
| Pcdhb3 |
A |
C |
18: 37,434,657 (GRCm39) |
I208L |
probably benign |
Het |
| Phlpp1 |
G |
T |
1: 106,317,420 (GRCm39) |
G1214W |
probably damaging |
Het |
| Ppp4r3a |
A |
T |
12: 101,025,053 (GRCm39) |
S149T |
possibly damaging |
Het |
| Pxdn |
T |
C |
12: 30,052,438 (GRCm39) |
C872R |
probably damaging |
Het |
| Rarb |
A |
G |
14: 16,548,419 (GRCm38) |
C101R |
probably damaging |
Het |
| Rcor3 |
A |
C |
1: 191,812,283 (GRCm39) |
V114G |
probably benign |
Het |
| Rnpepl1 |
A |
G |
1: 92,847,372 (GRCm39) |
Q653R |
probably benign |
Het |
| Rpap2 |
T |
A |
5: 107,768,324 (GRCm39) |
Y387* |
probably null |
Het |
| Rttn |
C |
T |
18: 89,004,035 (GRCm39) |
T343M |
possibly damaging |
Het |
| Samd11 |
T |
C |
4: 156,333,230 (GRCm39) |
T333A |
probably benign |
Het |
| Six5 |
T |
C |
7: 18,828,968 (GRCm39) |
L136P |
probably damaging |
Het |
| Slc12a5 |
T |
A |
2: 164,824,852 (GRCm39) |
M419K |
probably benign |
Het |
| Slc22a21 |
T |
C |
11: 53,851,226 (GRCm39) |
M179V |
probably benign |
Het |
| Slc35a4 |
A |
G |
18: 36,813,570 (GRCm39) |
D6G |
unknown |
Het |
| Spdye4c |
A |
T |
2: 128,434,261 (GRCm39) |
M1L |
probably benign |
Het |
| Svep1 |
A |
T |
4: 58,069,699 (GRCm39) |
C2696S |
possibly damaging |
Het |
| Tceanc2 |
T |
C |
4: 107,004,893 (GRCm39) |
N85S |
probably benign |
Het |
| Teddm2 |
G |
C |
1: 153,726,344 (GRCm39) |
L124V |
probably benign |
Het |
| Teddm2 |
A |
T |
1: 153,726,343 (GRCm39) |
L124Q |
probably damaging |
Het |
| Tgfbr1 |
T |
A |
4: 47,405,623 (GRCm39) |
W409R |
probably damaging |
Het |
| Tkt |
A |
G |
14: 30,280,755 (GRCm39) |
D62G |
probably damaging |
Het |
| Tnrc6b |
T |
A |
15: 80,768,501 (GRCm39) |
V1054D |
probably damaging |
Het |
| Trpm7 |
C |
A |
2: 126,641,126 (GRCm39) |
L1564F |
probably damaging |
Het |
| Vmn1r43 |
A |
T |
6: 89,846,803 (GRCm39) |
C228S |
probably benign |
Het |
| Vmn2r106 |
T |
C |
17: 20,487,883 (GRCm39) |
R839G |
probably damaging |
Het |
| Vmn2r5 |
G |
A |
3: 64,403,176 (GRCm39) |
T523I |
probably benign |
Het |
| Vwa3b |
C |
T |
1: 37,153,678 (GRCm39) |
Q507* |
probably null |
Het |
| Wrn |
C |
G |
8: 33,738,994 (GRCm39) |
W1278S |
probably benign |
Het |
| Zfp281 |
T |
G |
1: 136,553,190 (GRCm39) |
L56R |
probably damaging |
Het |
| Zfp407 |
G |
A |
18: 84,579,661 (GRCm39) |
T484I |
probably benign |
Het |
| Zfp451 |
T |
C |
1: 33,852,843 (GRCm39) |
T24A |
probably benign |
Het |
| Zfp607b |
T |
A |
7: 27,392,919 (GRCm39) |
F16I |
probably damaging |
Het |
| Zfp638 |
T |
A |
6: 83,905,670 (GRCm39) |
V41E |
possibly damaging |
Het |
|
| Other mutations in Lrriq1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00988:Lrriq1
|
APN |
10 |
102,997,757 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01523:Lrriq1
|
APN |
10 |
103,053,977 (GRCm39) |
nonsense |
probably null |
|
|
IGL01637:Lrriq1
|
APN |
10 |
103,051,489 (GRCm39) |
missense |
probably benign |
|
|
IGL02019:Lrriq1
|
APN |
10 |
103,014,661 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02153:Lrriq1
|
APN |
10 |
103,006,340 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02341:Lrriq1
|
APN |
10 |
103,060,802 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02343:Lrriq1
|
APN |
10 |
103,070,024 (GRCm39) |
splice site |
probably benign |
|
|
IGL02408:Lrriq1
|
APN |
10 |
102,982,142 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02431:Lrriq1
|
APN |
10 |
103,036,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02540:Lrriq1
|
APN |
10 |
103,050,880 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02558:Lrriq1
|
APN |
10 |
102,982,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02613:Lrriq1
|
APN |
10 |
102,980,409 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02642:Lrriq1
|
APN |
10 |
103,057,322 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03027:Lrriq1
|
APN |
10 |
103,063,057 (GRCm39) |
missense |
probably benign |
0.35 |
|
PIT4362001:Lrriq1
|
UTSW |
10 |
102,907,055 (GRCm39) |
missense |
probably benign |
0.26 |
|
R0050:Lrriq1
|
UTSW |
10 |
102,904,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0050:Lrriq1
|
UTSW |
10 |
102,904,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0068:Lrriq1
|
UTSW |
10 |
102,899,279 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0068:Lrriq1
|
UTSW |
10 |
102,899,279 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0124:Lrriq1
|
UTSW |
10 |
103,006,281 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0244:Lrriq1
|
UTSW |
10 |
103,051,634 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0323:Lrriq1
|
UTSW |
10 |
103,057,150 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0515:Lrriq1
|
UTSW |
10 |
102,904,829 (GRCm39) |
splice site |
probably null |
|
|
R0522:Lrriq1
|
UTSW |
10 |
102,997,638 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0701:Lrriq1
|
UTSW |
10 |
103,069,905 (GRCm39) |
missense |
probably benign |
|
|
R1220:Lrriq1
|
UTSW |
10 |
102,906,990 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1261:Lrriq1
|
UTSW |
10 |
103,069,998 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1262:Lrriq1
|
UTSW |
10 |
103,069,998 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1451:Lrriq1
|
UTSW |
10 |
103,038,376 (GRCm39) |
splice site |
probably benign |
|
|
R1642:Lrriq1
|
UTSW |
10 |
103,050,317 (GRCm39) |
missense |
probably benign |
0.13 |
|
R1643:Lrriq1
|
UTSW |
10 |
103,050,685 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1647:Lrriq1
|
UTSW |
10 |
103,006,509 (GRCm39) |
nonsense |
probably null |
|
|
R1830:Lrriq1
|
UTSW |
10 |
102,997,620 (GRCm39) |
missense |
probably benign |
|
|
R1843:Lrriq1
|
UTSW |
10 |
103,063,034 (GRCm39) |
splice site |
probably null |
|
|
R2128:Lrriq1
|
UTSW |
10 |
103,050,718 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2129:Lrriq1
|
UTSW |
10 |
103,050,718 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2199:Lrriq1
|
UTSW |
10 |
102,904,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2354:Lrriq1
|
UTSW |
10 |
103,025,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2495:Lrriq1
|
UTSW |
10 |
103,038,242 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2897:Lrriq1
|
UTSW |
10 |
103,063,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2898:Lrriq1
|
UTSW |
10 |
103,063,111 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2922:Lrriq1
|
UTSW |
10 |
103,050,536 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2939:Lrriq1
|
UTSW |
10 |
102,980,750 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2965:Lrriq1
|
UTSW |
10 |
103,050,761 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2966:Lrriq1
|
UTSW |
10 |
103,050,761 (GRCm39) |
missense |
probably benign |
0.07 |
|
R3081:Lrriq1
|
UTSW |
10 |
102,980,750 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3115:Lrriq1
|
UTSW |
10 |
103,006,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3745:Lrriq1
|
UTSW |
10 |
103,006,717 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3813:Lrriq1
|
UTSW |
10 |
103,051,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3814:Lrriq1
|
UTSW |
10 |
103,051,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3885:Lrriq1
|
UTSW |
10 |
103,051,967 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4378:Lrriq1
|
UTSW |
10 |
103,038,225 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4632:Lrriq1
|
UTSW |
10 |
103,057,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4633:Lrriq1
|
UTSW |
10 |
103,036,424 (GRCm39) |
nonsense |
probably null |
|
|
R4663:Lrriq1
|
UTSW |
10 |
102,899,273 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4702:Lrriq1
|
UTSW |
10 |
103,051,610 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R4793:Lrriq1
|
UTSW |
10 |
103,006,327 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4801:Lrriq1
|
UTSW |
10 |
103,057,179 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4802:Lrriq1
|
UTSW |
10 |
103,057,179 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4815:Lrriq1
|
UTSW |
10 |
102,980,739 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4872:Lrriq1
|
UTSW |
10 |
103,014,649 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4877:Lrriq1
|
UTSW |
10 |
103,069,899 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4894:Lrriq1
|
UTSW |
10 |
102,997,613 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4990:Lrriq1
|
UTSW |
10 |
103,036,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4991:Lrriq1
|
UTSW |
10 |
103,036,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5011:Lrriq1
|
UTSW |
10 |
103,025,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5013:Lrriq1
|
UTSW |
10 |
103,025,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5122:Lrriq1
|
UTSW |
10 |
103,023,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5282:Lrriq1
|
UTSW |
10 |
103,051,206 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5311:Lrriq1
|
UTSW |
10 |
103,050,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5567:Lrriq1
|
UTSW |
10 |
103,006,457 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R5643:Lrriq1
|
UTSW |
10 |
103,051,301 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5683:Lrriq1
|
UTSW |
10 |
103,009,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5916:Lrriq1
|
UTSW |
10 |
103,057,243 (GRCm39) |
nonsense |
probably null |
|
|
R6008:Lrriq1
|
UTSW |
10 |
103,006,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6022:Lrriq1
|
UTSW |
10 |
103,051,395 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6224:Lrriq1
|
UTSW |
10 |
103,051,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6254:Lrriq1
|
UTSW |
10 |
103,051,312 (GRCm39) |
missense |
probably benign |
0.15 |
|
R6311:Lrriq1
|
UTSW |
10 |
103,009,254 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6460:Lrriq1
|
UTSW |
10 |
103,036,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6502:Lrriq1
|
UTSW |
10 |
103,063,045 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6637:Lrriq1
|
UTSW |
10 |
103,057,293 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6719:Lrriq1
|
UTSW |
10 |
102,906,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6736:Lrriq1
|
UTSW |
10 |
103,017,750 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6928:Lrriq1
|
UTSW |
10 |
103,050,800 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6991:Lrriq1
|
UTSW |
10 |
103,023,319 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7174:Lrriq1
|
UTSW |
10 |
103,060,826 (GRCm39) |
missense |
probably benign |
|
|
R7241:Lrriq1
|
UTSW |
10 |
103,051,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7248:Lrriq1
|
UTSW |
10 |
103,059,611 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7287:Lrriq1
|
UTSW |
10 |
103,051,877 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7439:Lrriq1
|
UTSW |
10 |
103,050,380 (GRCm39) |
missense |
probably benign |
0.21 |
|
R7585:Lrriq1
|
UTSW |
10 |
103,050,807 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7611:Lrriq1
|
UTSW |
10 |
103,036,432 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7634:Lrriq1
|
UTSW |
10 |
103,036,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7767:Lrriq1
|
UTSW |
10 |
103,051,815 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7809:Lrriq1
|
UTSW |
10 |
103,051,678 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7910:Lrriq1
|
UTSW |
10 |
103,051,055 (GRCm39) |
nonsense |
probably null |
|
|
R8131:Lrriq1
|
UTSW |
10 |
103,051,572 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R8156:Lrriq1
|
UTSW |
10 |
102,992,196 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8211:Lrriq1
|
UTSW |
10 |
103,006,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8304:Lrriq1
|
UTSW |
10 |
103,069,929 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R8487:Lrriq1
|
UTSW |
10 |
103,050,914 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8500:Lrriq1
|
UTSW |
10 |
102,882,016 (GRCm39) |
missense |
|
|
|
R9013:Lrriq1
|
UTSW |
10 |
103,050,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9099:Lrriq1
|
UTSW |
10 |
103,051,864 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9155:Lrriq1
|
UTSW |
10 |
103,050,640 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9320:Lrriq1
|
UTSW |
10 |
103,057,144 (GRCm39) |
missense |
probably benign |
|
|
R9384:Lrriq1
|
UTSW |
10 |
103,006,458 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9469:Lrriq1
|
UTSW |
10 |
103,050,761 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9585:Lrriq1
|
UTSW |
10 |
103,051,250 (GRCm39) |
missense |
probably benign |
|
|
R9706:Lrriq1
|
UTSW |
10 |
102,881,902 (GRCm39) |
missense |
|
|
|
R9780:Lrriq1
|
UTSW |
10 |
103,025,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0026:Lrriq1
|
UTSW |
10 |
103,051,565 (GRCm39) |
nonsense |
probably null |
|
|
Z1088:Lrriq1
|
UTSW |
10 |
103,038,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Lrriq1
|
UTSW |
10 |
103,069,946 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Lrriq1
|
UTSW |
10 |
103,038,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Lrriq1
|
UTSW |
10 |
103,038,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TACTCCATGAGCAGATACTTCCC -3'
(R):5'- AGGATTGATCTCAAGAGCACCAC -3'
Sequencing Primer
(F):5'- TGAGCAGATACTTCCCTCATCAAGAG -3'
(R):5'- ACGCTTGTTTCTCTGAACGAATG -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation