Incidental Mutation 'R7402:Obscn'
ID 574283
Institutional Source Beutler Lab
Gene Symbol Obscn
Ensembl Gene ENSMUSG00000061462
Gene Name obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms OTTMUSG00000005786, LOC380698
MMRRC Submission
Accession Numbers

Genbank: NM_001171512.1, NM_199152.2; MGI: 2681862
Is this an essential gene? Possibly essential (E-score: 0.732) question?
Stock # R7402 (G1)
Quality Score 225.009
Status Not validated
Chromosome 11
Chromosomal Location 58994256-59136402 bp(-) (GRCm38)
Type of Mutation missense
DNA Base Change (assembly) T to G at 58995449 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Methionine to Leucine at position 7862 (M7862L)
Ref Sequence ENSEMBL: ENSMUSP00000038264 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000047441] [ENSMUST00000093061] [ENSMUST00000108809] [ENSMUST00000108810]
AlphaFold no structure available at present
Predicted Effect unknown
Transcript: ENSMUST00000047441
AA Change: M7862L
SMART Domains Protein: ENSMUSP00000038264
Gene: ENSMUSG00000061462
AA Change: M7862L

DomainStartEndE-ValueType
IGc2 21 88 8e-12 SMART
IGc2 121 190 8.31e-10 SMART
low complexity region 191 207 N/A INTRINSIC
IGc2 248 316 4.63e-8 SMART
IG 337 417 5.32e-8 SMART
IG_like 425 506 1.5e2 SMART
FN3 510 596 2.11e-9 SMART
IG 711 790 2.39e-1 SMART
IGc2 876 942 2.54e-5 SMART
IGc2 968 1034 2.54e-5 SMART
IGc2 1060 1126 4.49e-6 SMART
IGc2 1152 1218 7.82e-6 SMART
IGc2 1244 1310 5.16e-6 SMART
IGc2 1336 1402 1.93e-5 SMART
IGc2 1428 1494 1.93e-5 SMART
IGc2 1520 1586 1.93e-5 SMART
IGc2 1612 1678 1.93e-5 SMART
IGc2 1704 1770 1.93e-5 SMART
IGc2 1796 1862 7.94e-7 SMART
IG 1882 1962 5.37e-4 SMART
IG 1972 2051 9.93e-8 SMART
IG 2062 2141 2.48e-8 SMART
IG 2151 2230 3.89e-1 SMART
IG 2240 2319 1.92e0 SMART
IG 2329 2407 6.45e-7 SMART
IG 2452 2531 1.22e-7 SMART
IGc2 2637 2703 9.93e-8 SMART
low complexity region 2705 2716 N/A INTRINSIC
IG 2720 2799 2.44e0 SMART
IGc2 2815 2881 2.1e-6 SMART
IG 2898 2979 2.86e0 SMART
IGc2 2995 3061 8.38e-6 SMART
IG 3078 3157 1.2e-6 SMART
IG 3167 3248 1.42e-3 SMART
IGc2 3264 3330 3.85e-5 SMART
IGc2 3353 3419 3.13e-5 SMART
IGc2 3442 3507 3.3e-4 SMART
IGc2 3530 3595 5.84e-5 SMART
IGc2 3618 3683 1.29e-6 SMART
IG_like 3706 3771 3.16e-1 SMART
IGc2 3779 3844 1.46e-5 SMART
IGc2 3867 3932 1.56e-5 SMART
IGc2 3955 4020 1.19e-5 SMART
IGc2 4043 4108 1.93e-5 SMART
IG 4125 4203 1.85e-7 SMART
IGc2 4219 4285 5.08e-5 SMART
IGc2 4308 4374 1.11e-5 SMART
IGc2 4397 4465 6.71e-5 SMART
IG 4482 4564 2.06e-5 SMART
IG 4574 4655 5.01e-4 SMART
IG 4664 4746 1.04e-1 SMART
FN3 4749 4831 2.44e-14 SMART
IG 4858 4940 3.68e-2 SMART
IQ 5100 5122 3.65e-4 SMART
IGc2 5139 5207 8.72e-4 SMART
low complexity region 5215 5231 N/A INTRINSIC
low complexity region 5232 5248 N/A INTRINSIC
low complexity region 5251 5274 N/A INTRINSIC
IGc2 5369 5437 3.25e-12 SMART
low complexity region 5450 5466 N/A INTRINSIC
IG 5496 5580 1.55e0 SMART
IGc2 5612 5685 1.82e-6 SMART
low complexity region 5799 5829 N/A INTRINSIC
SH3 5832 5895 1.22e0 SMART
Pfam:RhoGEF 5926 6104 4.5e-21 PFAM
PH 6125 6235 2.74e-11 SMART
IGc2 6255 6323 3.73e-12 SMART
IGc2 6349 6418 1.18e-14 SMART
IGc2 6464 6531 1.7e-6 SMART
S_TKc 6562 6815 1.66e-79 SMART
Blast:STYKc 6843 6935 5e-39 BLAST
low complexity region 6939 6954 N/A INTRINSIC
low complexity region 7013 7029 N/A INTRINSIC
low complexity region 7146 7161 N/A INTRINSIC
low complexity region 7199 7219 N/A INTRINSIC
low complexity region 7499 7514 N/A INTRINSIC
IGc2 7538 7606 6.3e-10 SMART
FN3 7620 7698 9.33e-2 SMART
STYKc 7736 7988 8.55e-41 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000093061
SMART Domains Protein: ENSMUSP00000090749
Gene: ENSMUSG00000020455

DomainStartEndE-ValueType
RING 16 56 3.05e-9 SMART
BBOX 87 127 5.81e-6 SMART
coiled coil region 137 207 N/A INTRINSIC
PRY 285 337 4.1e-24 SMART
SPRY 338 457 2.58e-22 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000108809
SMART Domains Protein: ENSMUSP00000104437
Gene: ENSMUSG00000020455

DomainStartEndE-ValueType
RING 16 56 3.05e-9 SMART
BBOX 87 127 5.81e-6 SMART
coiled coil region 137 207 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000108810
SMART Domains Protein: ENSMUSP00000104438
Gene: ENSMUSG00000020455

DomainStartEndE-ValueType
RING 16 56 3.05e-9 SMART
BBOX 87 127 5.81e-6 SMART
coiled coil region 137 207 N/A INTRINSIC
PRY 301 353 4.1e-24 SMART
SPRY 354 473 2.58e-22 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000138587
AA Change: M2382L

PolyPhen 2 Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)
SMART Domains Protein: ENSMUSP00000121092
Gene: ENSMUSG00000061462
AA Change: M2382L

DomainStartEndE-ValueType
IG 2 83 1.28e-1 SMART
low complexity region 186 216 N/A INTRINSIC
SH3 219 282 1.22e0 SMART
Pfam:RhoGEF 313 491 6.1e-22 PFAM
PH 512 622 2.74e-11 SMART
IGc2 642 710 3.73e-12 SMART
IGc2 736 805 1.18e-14 SMART
low complexity region 843 857 N/A INTRINSIC
IGc2 985 1052 1.7e-6 SMART
S_TKc 1083 1336 1.66e-79 SMART
Blast:STYKc 1364 1456 1e-38 BLAST
low complexity region 1460 1475 N/A INTRINSIC
low complexity region 1534 1550 N/A INTRINSIC
low complexity region 1667 1682 N/A INTRINSIC
low complexity region 1720 1740 N/A INTRINSIC
low complexity region 2020 2035 N/A INTRINSIC
IGc2 2059 2127 6.3e-10 SMART
FN3 2141 2219 9.33e-2 SMART
STYKc 2257 2509 8.55e-41 SMART
Coding Region Coverage
  • 1x: 100.0%
  • 3x: 100.0%
  • 10x: 99.8%
  • 20x: 99.3%
Validation Efficiency
MGI Phenotype FUNCTION: The obscurin gene spans more than 150 kb, contains over 80 exons and encodes a protein of approximately 800 kDa. The encoded protein contains 68 Ig domains, 2 fibronectin domains, 1 calcium/calmodulin-binding domain, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. This protein is one of three giant sacromeric signaling proteins that includes titin and nebulin. It may have a role in the organization of myofibrils during assembly and also may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been described although the full-length nature is not known for all splicing variants. [provided by RefSeq, Jan 2010]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit centrally localized nuclei in muscle fibers and mild myopathy in aged mice. [provided by MGI curators]
Allele List at MGI

All alleles(1) : Targeted, other(1)
Other mutations in this stock
Total: 98 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcc4 G T 14: 118,706,075 P12Q probably damaging Het
Acsf3 A G 8: 122,780,424 Y152C probably damaging Het
Adam22 T A 5: 8,095,049 Q803L possibly damaging Het
Adamtsl3 G A 7: 82,578,617 V1337I probably damaging Het
Adra1b T C 11: 43,776,018 D464G possibly damaging Het
Alpk3 T A 7: 81,076,912 I115K probably benign Het
Amdhd2 A G 17: 24,161,683 S96P Het
Ankib1 T G 5: 3,769,586 D111A probably benign Het
Arhgef2 A G 3: 88,633,566 D216G probably damaging Het
Astn1 A T 1: 158,552,855 probably benign Het
Atrn T A 2: 130,947,600 W328R probably damaging Het
Atxn7 A T 14: 14,095,427 H375L probably damaging Het
BC003331 A G 1: 150,386,356 probably null Het
Btaf1 A T 19: 37,003,515 N1579Y probably damaging Het
Cacna1b A T 2: 24,607,659 L2079Q probably benign Het
Ccdc102a T C 8: 94,903,353 K520R probably damaging Het
Cd2ap T C 17: 42,805,163 H602R possibly damaging Het
Cdkn2aip A G 8: 47,711,373 V435A possibly damaging Het
Cenpf A T 1: 189,659,378 Y735* probably null Het
Cep350 T A 1: 155,928,215 I1041L probably benign Het
Ckap4 A G 10: 84,527,999 V400A probably damaging Het
Comp T A 8: 70,377,204 D359E probably benign Het
Coq10b A C 1: 55,061,341 K61N probably benign Het
Csmd2 A C 4: 128,322,095 S548R Het
Csmd2 G A 4: 128,322,096 S548N Het
Ctif A G 18: 75,611,736 I99T probably benign Het
Ctns T G 11: 73,193,077 T40P possibly damaging Het
Cyp11b1 C T 15: 74,840,825 R129H probably damaging Het
Cyp2c68 A T 19: 39,740,874 N56K probably benign Het
D6Wsu163e A G 6: 126,962,005 K401R probably damaging Het
Dstn T A 2: 143,938,448 C23S probably benign Het
Fam214a C A 9: 75,006,386 Y107* probably null Het
Fam72a A T 1: 131,538,875 E132D probably damaging Het
Fam72a G T 1: 131,538,876 E133* probably null Het
Gbp8 T A 5: 105,031,295 I113F probably damaging Het
Gm3095 A T 14: 3,964,463 R60S possibly damaging Het
Gpa33 A T 1: 166,152,694 M109L probably damaging Het
Grik2 A G 10: 49,535,397 L215P probably damaging Het
Gucy2g A C 19: 55,206,293 F897L probably damaging Het
Hinfp A G 9: 44,298,017 L295P probably damaging Het
Ift122 T C 6: 115,894,322 V526A probably benign Het
Ighv5-12 T C 12: 113,702,233 T82A probably benign Het
Il18rap T A 1: 40,524,951 S76R probably benign Het
Itga6 A T 2: 71,853,553 N1045I probably benign Het
Kctd21 A T 7: 97,347,763 I148F possibly damaging Het
Kif28 T A 1: 179,740,079 H42L probably benign Het
Kmt2c A C 5: 25,395,420 C326W probably damaging Het
Knl1 T A 2: 119,095,226 L1912* probably null Het
Lrfn1 A T 7: 28,459,522 I289F probably damaging Het
Lrriq1 T C 10: 103,221,324 K205R possibly damaging Het
Mbd5 A T 2: 49,257,554 N592I probably damaging Het
Mbl2 A G 19: 30,239,402 N205D possibly damaging Het
Mcm4 C A 16: 15,637,178 M1I probably null Het
Mgat4a T A 1: 37,454,784 H327L probably damaging Het
Miox A G 15: 89,335,003 D16G probably benign Het
Mvk C A 5: 114,455,978 P298Q possibly damaging Het
Nol6 A G 4: 41,118,699 L726P probably damaging Het
Nos1 T C 5: 117,949,815 I1381T probably benign Het
Nup98 A T 7: 102,134,937 S1063T probably benign Het
Obsl1 T C 1: 75,487,704 T1653A probably benign Het
Olfr1044 A G 2: 86,171,202 I205T probably benign Het
Olfr1202 G T 2: 88,817,343 M57I probably damaging Het
Olfr1497 C T 19: 13,794,994 V206I probably damaging Het
Olfr968 T A 9: 39,771,964 T279S probably benign Het
Pcdhb20 A G 18: 37,504,952 Y177C probably benign Het
Pcdhb3 A C 18: 37,301,604 I208L probably benign Het
Phlpp1 G T 1: 106,389,690 G1214W probably damaging Het
Ppp4r3a A T 12: 101,058,794 S149T possibly damaging Het
Pxdn T C 12: 30,002,439 C872R probably damaging Het
Rarb A G 14: 16,548,419 C101R probably damaging Het
Rcor3 A C 1: 192,127,983 V114G probably benign Het
Rnpepl1 A G 1: 92,919,650 Q653R probably benign Het
Rpap2 T A 5: 107,620,458 Y387* probably null Het
Rttn C T 18: 88,985,911 T343M possibly damaging Het
Samd11 T C 4: 156,248,773 T333A probably benign Het
Six5 T C 7: 19,095,043 L136P probably damaging Het
Slc12a5 T A 2: 164,982,932 M419K probably benign Het
Slc22a21 T C 11: 53,960,400 M179V probably benign Het
Slc35a4 A G 18: 36,680,517 D6G unknown Het
Spdye4c A T 2: 128,592,341 M1L probably benign Het
Svep1 A T 4: 58,069,699 C2696S possibly damaging Het
Tceanc2 T C 4: 107,147,696 N85S probably benign Het
Teddm2 A T 1: 153,850,597 L124Q probably damaging Het
Teddm2 G C 1: 153,850,598 L124V probably benign Het
Tgfbr1 T A 4: 47,405,623 W409R probably damaging Het
Tkt A G 14: 30,558,798 D62G probably damaging Het
Tnrc6b T A 15: 80,884,300 V1054D probably damaging Het
Trpm7 C A 2: 126,799,206 L1564F probably damaging Het
Vmn1r43 A T 6: 89,869,821 C228S probably benign Het
Vmn2r106 T C 17: 20,267,621 R839G probably damaging Het
Vmn2r5 G A 3: 64,495,755 T523I probably benign Het
Vwa3b C T 1: 37,114,597 Q507* probably null Het
Wrn C G 8: 33,248,966 W1278S probably benign Het
Zfp281 T G 1: 136,625,452 L56R probably damaging Het
Zfp407 G A 18: 84,561,536 T484I probably benign Het
Zfp451 T C 1: 33,813,762 T24A probably benign Het
Zfp607b T A 7: 27,693,494 F16I probably damaging Het
Zfp638 T A 6: 83,928,688 V41E possibly damaging Het
Other mutations in Obscn
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00160:Obscn APN 11 59002057 missense probably benign 0.01
IGL00417:Obscn APN 11 59006788 missense unknown
IGL01018:Obscn APN 11 59128069 missense probably damaging 0.99
IGL01083:Obscn APN 11 59036093 missense probably damaging 0.99
IGL01109:Obscn APN 11 59133762 missense probably damaging 1.00
IGL01139:Obscn APN 11 59078352 missense probably damaging 1.00
IGL01361:Obscn APN 11 59028889 missense probably damaging 0.99
IGL01370:Obscn APN 11 58995563 critical splice acceptor site probably null
IGL01409:Obscn APN 11 59031058 missense probably damaging 1.00
IGL01432:Obscn APN 11 59033757 missense probably benign 0.27
IGL01527:Obscn APN 11 59064417 missense possibly damaging 0.83
IGL01543:Obscn APN 11 59042117 missense probably benign 0.01
IGL01578:Obscn APN 11 58999680 missense unknown
IGL01603:Obscn APN 11 59037805 missense probably damaging 1.00
IGL01750:Obscn APN 11 59031639 missense probably damaging 1.00
IGL01765:Obscn APN 11 59115784 missense possibly damaging 0.58
IGL01805:Obscn APN 11 59132596 missense probably damaging 0.99
IGL01816:Obscn APN 11 58995779 splice site probably benign
IGL01885:Obscn APN 11 59074968 missense possibly damaging 0.60
IGL01911:Obscn APN 11 59008595 nonsense probably null
IGL01963:Obscn APN 11 59020541 missense probably benign 0.16
IGL02012:Obscn APN 11 59076507 missense probably benign 0.03
IGL02096:Obscn APN 11 59080704 missense probably damaging 0.98
IGL02125:Obscn APN 11 59093326 missense possibly damaging 0.95
IGL02125:Obscn APN 11 59022362 missense probably damaging 1.00
IGL02203:Obscn APN 11 59082308 missense probably damaging 1.00
IGL02232:Obscn APN 11 59038978 missense probably damaging 0.97
IGL02262:Obscn APN 11 59028533 missense possibly damaging 0.88
IGL02304:Obscn APN 11 59076622 missense probably damaging 1.00
IGL02306:Obscn APN 11 58999671 missense unknown
IGL02323:Obscn APN 11 59008522 missense possibly damaging 0.51
IGL02341:Obscn APN 11 59135825 missense probably benign 0.09
IGL02342:Obscn APN 11 59001088 missense probably benign 0.00
IGL02352:Obscn APN 11 59001027 missense probably benign 0.10
IGL02397:Obscn APN 11 59076899 missense possibly damaging 0.67
IGL02405:Obscn APN 11 59132602 missense probably damaging 0.96
IGL02427:Obscn APN 11 59067162 missense probably damaging 1.00
IGL02479:Obscn APN 11 59056227 splice site probably benign
IGL02512:Obscn APN 11 59028517 missense probably damaging 1.00
IGL02566:Obscn APN 11 59068147 missense probably damaging 1.00
IGL02613:Obscn APN 11 59002132 missense probably benign 0.03
IGL02634:Obscn APN 11 59054785 missense probably damaging 1.00
IGL02680:Obscn APN 11 59000020 missense unknown
IGL02715:Obscn APN 11 59080311 missense probably benign 0.25
IGL02718:Obscn APN 11 59077858 missense probably damaging 1.00
IGL02723:Obscn APN 11 59124620 missense probably benign 0.17
IGL02735:Obscn APN 11 59093349 missense probably damaging 1.00
IGL02951:Obscn APN 11 58994513 splice site probably benign
IGL03004:Obscn APN 11 59028587 missense probably damaging 1.00
IGL03078:Obscn APN 11 59078798 splice site probably null
IGL03114:Obscn APN 11 59000539 missense unknown
IGL03125:Obscn APN 11 59061648 missense probably damaging 1.00
IGL03150:Obscn APN 11 59051723 missense probably damaging 1.00
IGL03156:Obscn APN 11 59054896 missense probably damaging 1.00
IGL03169:Obscn APN 11 59073296 missense probably damaging 1.00
IGL03297:Obscn APN 11 59060886 missense possibly damaging 0.83
IGL03326:Obscn APN 11 59032902 missense probably damaging 1.00
IGL03345:Obscn APN 11 58995482 unclassified probably benign
IGL03348:Obscn APN 11 59050362 missense probably damaging 1.00
IGL03355:Obscn APN 11 59037792 missense probably damaging 1.00
IGL03377:Obscn APN 11 58999873 missense probably damaging 1.00
IGL03396:Obscn APN 11 59073578 missense probably benign 0.12
IGL03405:Obscn APN 11 59000124 missense unknown
boeuf UTSW 11 59133194 missense probably benign 0.37
Bull UTSW 11 59032918 missense possibly damaging 0.85
Deluge UTSW 11 59007614 missense unknown
ducking UTSW 11 59080969 unclassified probably benign
Goose UTSW 11 59050480 missense probably benign 0.23
Obscurity UTSW 11 58994700 nonsense probably null
Tallow UTSW 11 59076993 missense possibly damaging 0.95
Turducken UTSW 11 59051521 splice site probably benign
BB001:Obscn UTSW 11 59112555 missense probably benign 0.27
BB002:Obscn UTSW 11 59112555 missense probably benign 0.27
BB011:Obscn UTSW 11 59112555 missense probably benign 0.27
BB012:Obscn UTSW 11 59112555 missense probably benign 0.27
IGL02802:Obscn UTSW 11 59000484 missense unknown
N/A - 535:Obscn UTSW 11 59000308 missense possibly damaging 0.67
PIT4131001:Obscn UTSW 11 59067064 critical splice donor site probably null
PIT4453001:Obscn UTSW 11 59060976 missense probably damaging 1.00
PIT4453001:Obscn UTSW 11 59069834 missense possibly damaging 0.76
PIT4504001:Obscn UTSW 11 59133122 missense probably damaging 1.00
PIT4651001:Obscn UTSW 11 59041681 missense probably damaging 0.99
R0033:Obscn UTSW 11 58994746 unclassified probably benign
R0041:Obscn UTSW 11 59043977 missense probably damaging 1.00
R0042:Obscn UTSW 11 59052585 missense probably damaging 1.00
R0064:Obscn UTSW 11 59027466 missense probably damaging 1.00
R0064:Obscn UTSW 11 59027466 missense probably damaging 1.00
R0071:Obscn UTSW 11 59064201 missense possibly damaging 0.85
R0077:Obscn UTSW 11 59051521 splice site probably benign
R0083:Obscn UTSW 11 59022374 missense probably damaging 1.00
R0089:Obscn UTSW 11 59000062 missense unknown
R0092:Obscn UTSW 11 59051247 missense possibly damaging 0.96
R0103:Obscn UTSW 11 59062696 nonsense probably null
R0103:Obscn UTSW 11 59062696 nonsense probably null
R0108:Obscn UTSW 11 59022374 missense probably damaging 1.00
R0152:Obscn UTSW 11 59052576 missense probably benign 0.06
R0268:Obscn UTSW 11 59067272 missense possibly damaging 0.78
R0271:Obscn UTSW 11 59056742 intron probably benign
R0281:Obscn UTSW 11 59038615 missense probably damaging 1.00
R0329:Obscn UTSW 11 59040441 missense probably damaging 1.00
R0329:Obscn UTSW 11 59052506 missense probably damaging 1.00
R0360:Obscn UTSW 11 59128281 missense probably benign 0.22
R0364:Obscn UTSW 11 59128281 missense probably benign 0.22
R0382:Obscn UTSW 11 59040306 missense probably damaging 1.00
R0386:Obscn UTSW 11 59136339 missense probably damaging 1.00
R0403:Obscn UTSW 11 59076540 missense probably damaging 1.00
R0413:Obscn UTSW 11 59002997 missense probably benign 0.03
R0437:Obscn UTSW 11 58995088 unclassified probably benign
R0442:Obscn UTSW 11 59002174 splice site probably benign
R0445:Obscn UTSW 11 58999335 missense unknown
R0446:Obscn UTSW 11 58995412 unclassified probably benign
R0454:Obscn UTSW 11 58999623 missense unknown
R0463:Obscn UTSW 11 59061530 missense probably benign 0.07
R0479:Obscn UTSW 11 59112707 missense probably damaging 1.00
R0480:Obscn UTSW 11 59133946 nonsense probably null
R0504:Obscn UTSW 11 59008507 critical splice donor site probably null
R0507:Obscn UTSW 11 59029341 missense probably damaging 1.00
R0513:Obscn UTSW 11 59061522 missense possibly damaging 0.81
R0541:Obscn UTSW 11 59081984 missense probably damaging 1.00
R0551:Obscn UTSW 11 59107862 nonsense probably null
R0573:Obscn UTSW 11 59036079 missense probably damaging 1.00
R0599:Obscn UTSW 11 59073696 missense probably damaging 1.00
R0637:Obscn UTSW 11 59051644 missense probably damaging 1.00
R0637:Obscn UTSW 11 59082776 missense probably damaging 0.96
R0653:Obscn UTSW 11 59007708 unclassified probably benign
R0712:Obscn UTSW 11 59049445 missense possibly damaging 0.72
R0715:Obscn UTSW 11 59050480 missense probably benign 0.23
R0729:Obscn UTSW 11 59032709 missense probably damaging 1.00
R0741:Obscn UTSW 11 59063453 frame shift probably null
R0745:Obscn UTSW 11 59082239 missense probably benign 0.14
R0751:Obscn UTSW 11 59081819 missense probably damaging 1.00
R0834:Obscn UTSW 11 59133278 missense probably benign 0.25
R0863:Obscn UTSW 11 58995415 unclassified probably benign
R0909:Obscn UTSW 11 59075064 missense probably damaging 1.00
R0965:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R0969:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R0980:Obscn UTSW 11 58998061 missense possibly damaging 0.92
R1017:Obscn UTSW 11 58998353 missense unknown
R1103:Obscn UTSW 11 59021483 missense probably damaging 1.00
R1107:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R1128:Obscn UTSW 11 59028943 missense probably null 0.71
R1164:Obscn UTSW 11 59036087 missense possibly damaging 0.65
R1192:Obscn UTSW 11 59067199 missense probably benign 0.33
R1298:Obscn UTSW 11 59054897 missense possibly damaging 0.65
R1331:Obscn UTSW 11 59086928 missense probably benign 0.09
R1333:Obscn UTSW 11 59080317 missense probably damaging 0.99
R1341:Obscn UTSW 11 59029372 splice site probably benign
R1385:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R1386:Obscn UTSW 11 59133853 missense probably damaging 1.00
R1390:Obscn UTSW 11 59093448 missense probably damaging 1.00
R1460:Obscn UTSW 11 59055966 missense probably damaging 1.00
R1495:Obscn UTSW 11 59080160 missense probably damaging 0.99
R1496:Obscn UTSW 11 59031036 missense probably benign 0.01
R1524:Obscn UTSW 11 59115855 missense probably damaging 1.00
R1526:Obscn UTSW 11 59028586 missense probably damaging 1.00
R1537:Obscn UTSW 11 59000749 missense unknown
R1554:Obscn UTSW 11 59003648 missense unknown
R1561:Obscn UTSW 11 59036073 missense probably damaging 1.00
R1589:Obscn UTSW 11 59036075 missense possibly damaging 0.89
R1615:Obscn UTSW 11 59099825 missense probably benign 0.09
R1627:Obscn UTSW 11 59112638 missense probably benign 0.14
R1634:Obscn UTSW 11 59076896 missense probably damaging 1.00
R1636:Obscn UTSW 11 59122637 missense probably damaging 1.00
R1681:Obscn UTSW 11 59103325 missense probably damaging 1.00
R1686:Obscn UTSW 11 59106287 splice site probably benign
R1713:Obscn UTSW 11 59079886 missense probably damaging 1.00
R1730:Obscn UTSW 11 59073633 missense probably damaging 1.00
R1781:Obscn UTSW 11 59106337 missense probably damaging 1.00
R1783:Obscn UTSW 11 59073633 missense probably damaging 1.00
R1793:Obscn UTSW 11 59077780 missense probably damaging 1.00
R1796:Obscn UTSW 11 59029337 missense possibly damaging 0.94
R1801:Obscn UTSW 11 58998321 missense unknown
R1824:Obscn UTSW 11 58994832 unclassified probably benign
R1856:Obscn UTSW 11 59040296 missense probably damaging 1.00
R1866:Obscn UTSW 11 59060915 missense probably benign 0.34
R1878:Obscn UTSW 11 58995553 missense probably damaging 0.99
R1883:Obscn UTSW 11 59078203 missense probably damaging 1.00
R1926:Obscn UTSW 11 59063474 missense
R1967:Obscn UTSW 11 59135709 nonsense probably null
R1975:Obscn UTSW 11 59067729 missense probably damaging 1.00
R1992:Obscn UTSW 11 58995827 unclassified probably benign
R2021:Obscn UTSW 11 59067174 missense probably benign 0.40
R2066:Obscn UTSW 11 59135732 missense possibly damaging 0.59
R2074:Obscn UTSW 11 59069281 missense probably damaging 0.99
R2074:Obscn UTSW 11 59132652 missense probably damaging 1.00
R2081:Obscn UTSW 11 59034182 missense possibly damaging 0.90
R2083:Obscn UTSW 11 59073631 nonsense probably null
R2086:Obscn UTSW 11 59078256 missense probably damaging 0.99
R2095:Obscn UTSW 11 59093584 splice site probably null
R2098:Obscn UTSW 11 59069991 missense probably damaging 1.00
R2114:Obscn UTSW 11 59131658 missense probably damaging 0.99
R2138:Obscn UTSW 11 59003665 nonsense probably null
R2193:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2194:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2210:Obscn UTSW 11 59068087 missense probably damaging 1.00
R2233:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2234:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2287:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2288:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2351:Obscn UTSW 11 59112612 missense probably damaging 0.99
R2376:Obscn UTSW 11 59069124 missense probably damaging 1.00
R2384:Obscn UTSW 11 59042837 critical splice donor site probably null
R2401:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2402:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2403:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2424:Obscn UTSW 11 58994451 unclassified probably benign
R2433:Obscn UTSW 11 59039086 splice site probably null
R2445:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2446:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2447:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2449:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2483:Obscn UTSW 11 59080146 missense probably damaging 1.00
R2484:Obscn UTSW 11 59007540 unclassified probably benign
R2496:Obscn UTSW 11 59103442 missense probably damaging 1.00
R2510:Obscn UTSW 11 59042314 splice site probably benign
R2851:Obscn UTSW 11 59030018 critical splice donor site probably null
R2878:Obscn UTSW 11 59056188 missense possibly damaging 0.94
R2879:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2885:Obscn UTSW 11 59086748 missense probably damaging 1.00
R2885:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2886:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R2985:Obscn UTSW 11 59133089 missense probably damaging 1.00
R3013:Obscn UTSW 11 59060918 missense probably damaging 1.00
R3118:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R3236:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R3237:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R3432:Obscn UTSW 11 59031177 missense probably damaging 1.00
R3694:Obscn UTSW 11 59078395 missense probably damaging 1.00
R3716:Obscn UTSW 11 59082661 missense probably damaging 1.00
R3717:Obscn UTSW 11 59082661 missense probably damaging 1.00
R3743:Obscn UTSW 11 59079085 missense probably damaging 0.99
R3760:Obscn UTSW 11 59028580 missense probably damaging 1.00
R3795:Obscn UTSW 11 59031841 missense probably damaging 1.00
R3857:Obscn UTSW 11 59080969 unclassified probably benign
R3858:Obscn UTSW 11 59080969 unclassified probably benign
R3862:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R3863:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R3864:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R3881:Obscn UTSW 11 59056949 missense probably damaging 1.00
R3890:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R3903:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R3923:Obscn UTSW 11 59060928 missense possibly damaging 0.96
R3944:Obscn UTSW 11 59132547 missense probably damaging 1.00
R3947:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R3948:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R3955:Obscn UTSW 11 59036768 missense probably damaging 1.00
R3970:Obscn UTSW 11 59051662 missense probably damaging 1.00
R3971:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R4001:Obscn UTSW 11 59134569 missense probably damaging 1.00
R4005:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R4017:Obscn UTSW 11 59132622 missense probably damaging 1.00
R4028:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R4029:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R4041:Obscn UTSW 11 59051531 nonsense probably null
R4061:Obscn UTSW 11 59008532 missense probably damaging 1.00
R4062:Obscn UTSW 11 59082710 missense probably damaging 0.99
R4072:Obscn UTSW 11 58997183 missense unknown
R4078:Obscn UTSW 11 59038363 missense probably benign 0.41
R4079:Obscn UTSW 11 59038363 missense probably benign 0.41
R4092:Obscn UTSW 11 59056060 missense probably benign 0.12
R4106:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R4108:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R4403:Obscn UTSW 11 59069093 missense possibly damaging 0.95
R4477:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R4478:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R4480:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R4489:Obscn UTSW 11 59031591 missense possibly damaging 0.74
R4531:Obscn UTSW 11 59007874 unclassified probably benign
R4551:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R4552:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R4553:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R4558:Obscn UTSW 11 59131646 missense possibly damaging 0.90
R4570:Obscn UTSW 11 59006828 splice site probably null
R4575:Obscn UTSW 11 59122772 missense probably damaging 0.99
R4593:Obscn UTSW 11 59133249 missense probably damaging 1.00
R4604:Obscn UTSW 11 59080205 missense probably damaging 1.00
R4604:Obscn UTSW 11 59122746 missense probably damaging 0.96
R4625:Obscn UTSW 11 59067258 missense probably damaging 1.00
R4646:Obscn UTSW 11 59124570 nonsense probably null
R4651:Obscn UTSW 11 59038877 missense probably damaging 1.00
R4652:Obscn UTSW 11 59038877 missense probably damaging 1.00
R4657:Obscn UTSW 11 59042290 missense probably damaging 1.00
R4658:Obscn UTSW 11 59054288 nonsense probably null
R4662:Obscn UTSW 11 58999596 missense unknown
R4665:Obscn UTSW 11 59124752 missense probably damaging 1.00
R4718:Obscn UTSW 11 59021954 missense probably damaging 1.00
R4736:Obscn UTSW 11 59063536 missense probably damaging 1.00
R4746:Obscn UTSW 11 59079808 critical splice donor site probably null
R4754:Obscn UTSW 11 59036043 missense possibly damaging 0.81
R4758:Obscn UTSW 11 59003363 missense unknown
R4758:Obscn UTSW 11 59135917 missense probably damaging 0.98
R4766:Obscn UTSW 11 59012742 missense probably damaging 1.00
R4798:Obscn UTSW 11 59069859 missense probably damaging 0.99
R4810:Obscn UTSW 11 59031591 missense possibly damaging 0.74
R4819:Obscn UTSW 11 59038848 missense probably damaging 0.97
R4821:Obscn UTSW 11 59006826 splice site probably benign
R4821:Obscn UTSW 11 59040467 missense probably damaging 1.00
R4822:Obscn UTSW 11 59022333 missense probably benign 0.11
R4828:Obscn UTSW 11 59086670 missense possibly damaging 0.93
R4829:Obscn UTSW 11 59054246 missense probably null 0.53
R4830:Obscn UTSW 11 59067607 missense probably damaging 1.00
R4859:Obscn UTSW 11 59082023 missense possibly damaging 0.89
R4870:Obscn UTSW 11 59136206 missense probably damaging 1.00
R4909:Obscn UTSW 11 59061465 missense possibly damaging 0.52
R4955:Obscn UTSW 11 59069172 missense probably benign 0.31
R4973:Obscn UTSW 11 59132466 missense probably damaging 1.00
R4993:Obscn UTSW 11 59124761 missense possibly damaging 0.48
R5034:Obscn UTSW 11 59061676 nonsense probably null
R5054:Obscn UTSW 11 59073617 missense probably damaging 1.00
R5077:Obscn UTSW 11 59044057 missense probably damaging 0.98
R5126:Obscn UTSW 11 59077063 missense probably damaging 1.00
R5135:Obscn UTSW 11 59129653 missense probably damaging 1.00
R5161:Obscn UTSW 11 59028604 missense probably damaging 1.00
R5161:Obscn UTSW 11 59064310 missense possibly damaging 0.60
R5195:Obscn UTSW 11 59060850 missense possibly damaging 0.78
R5222:Obscn UTSW 11 59044145 missense possibly damaging 0.80
R5260:Obscn UTSW 11 59003369 missense probably damaging 1.00
R5301:Obscn UTSW 11 59135408 missense probably damaging 1.00
R5305:Obscn UTSW 11 59012715 missense possibly damaging 0.83
R5323:Obscn UTSW 11 58996877 missense probably benign
R5333:Obscn UTSW 11 59062692 missense probably damaging 1.00
R5366:Obscn UTSW 11 59080260 missense probably damaging 1.00
R5368:Obscn UTSW 11 59069026 critical splice donor site probably null
R5408:Obscn UTSW 11 59051611 missense probably damaging 1.00
R5439:Obscn UTSW 11 59000128 nonsense probably null
R5536:Obscn UTSW 11 59107871 missense probably damaging 1.00
R5561:Obscn UTSW 11 59036093 missense probably damaging 0.99
R5573:Obscn UTSW 11 59034705 missense possibly damaging 0.94
R5582:Obscn UTSW 11 59099976 splice site probably null
R5586:Obscn UTSW 11 59001468 nonsense probably null
R5607:Obscn UTSW 11 59122848 missense probably benign 0.22
R5700:Obscn UTSW 11 59133194 missense probably benign 0.37
R5706:Obscn UTSW 11 59076256 missense probably damaging 1.00
R5718:Obscn UTSW 11 59036808 missense probably damaging 1.00
R5771:Obscn UTSW 11 59000707 missense unknown
R5772:Obscn UTSW 11 59056144 missense probably damaging 0.99
R5786:Obscn UTSW 11 59032691 missense probably damaging 1.00
R5807:Obscn UTSW 11 59079650 missense probably damaging 1.00
R5815:Obscn UTSW 11 59082189 splice site probably null
R5835:Obscn UTSW 11 59002081 missense probably benign 0.03
R5835:Obscn UTSW 11 59042127 missense probably damaging 1.00
R5846:Obscn UTSW 11 59038609 missense probably damaging 1.00
R5851:Obscn UTSW 11 58994700 nonsense probably null
R5933:Obscn UTSW 11 58998505 missense unknown
R5935:Obscn UTSW 11 59006813 missense unknown
R5974:Obscn UTSW 11 59076547 missense probably damaging 1.00
R5975:Obscn UTSW 11 59122619 critical splice donor site probably null
R6014:Obscn UTSW 11 59038864 missense probably damaging 1.00
R6026:Obscn UTSW 11 59067090 missense probably damaging 0.98
R6082:Obscn UTSW 11 58999567 missense unknown
R6124:Obscn UTSW 11 59079044 missense probably benign 0.45
R6130:Obscn UTSW 11 59077945 missense possibly damaging 0.90
R6160:Obscn UTSW 11 59051785 missense probably damaging 1.00
R6169:Obscn UTSW 11 59000499 missense unknown
R6177:Obscn UTSW 11 59032664 missense probably damaging 1.00
R6189:Obscn UTSW 11 59069934 missense probably benign 0.00
R6192:Obscn UTSW 11 58998038 missense unknown
R6195:Obscn UTSW 11 58997207 missense probably damaging 0.98
R6208:Obscn UTSW 11 59067648 missense possibly damaging 0.81
R6232:Obscn UTSW 11 59052511 nonsense probably null
R6233:Obscn UTSW 11 58997207 missense probably damaging 0.98
R6273:Obscn UTSW 11 59076993 missense possibly damaging 0.95
R6280:Obscn UTSW 11 59063683 missense possibly damaging 0.82
R6317:Obscn UTSW 11 59069895 missense probably damaging 1.00
R6345:Obscn UTSW 11 59053696 missense probably damaging 0.99
R6378:Obscn UTSW 11 59073746 missense probably damaging 1.00
R6382:Obscn UTSW 11 58999413 missense unknown
R6382:Obscn UTSW 11 59042208 missense probably damaging 0.99
R6415:Obscn UTSW 11 59035130 missense probably damaging 0.99
R6433:Obscn UTSW 11 59051558 missense probably benign 0.14
R6457:Obscn UTSW 11 59080771 missense probably damaging 0.99
R6508:Obscn UTSW 11 59054147 splice site probably null
R6611:Obscn UTSW 11 59064230 splice site probably null
R6614:Obscn UTSW 11 59012801 missense probably benign 0.01
R6645:Obscn UTSW 11 59085262 missense probably damaging 0.97
R6646:Obscn UTSW 11 59082718 missense possibly damaging 0.72
R6659:Obscn UTSW 11 59039009 missense probably damaging 1.00
R6723:Obscn UTSW 11 59054998 missense probably damaging 0.99
R6733:Obscn UTSW 11 59028595 missense probably damaging 0.99
R6755:Obscn UTSW 11 59103326 missense probably damaging 1.00
R6770:Obscn UTSW 11 59044036 missense possibly damaging 0.88
R6820:Obscn UTSW 11 59051193 missense probably damaging 1.00
R6823:Obscn UTSW 11 59067943 critical splice donor site probably null
R6850:Obscn UTSW 11 59002129 missense possibly damaging 0.92
R6850:Obscn UTSW 11 59068124 missense possibly damaging 0.93
R6862:Obscn UTSW 11 58995453 unclassified probably benign
R6884:Obscn UTSW 11 59078302 missense probably damaging 1.00
R6894:Obscn UTSW 11 59132682 missense probably benign 0.43
R6906:Obscn UTSW 11 59032918 missense possibly damaging 0.85
R6944:Obscn UTSW 11 59038930 missense probably damaging 1.00
R6948:Obscn UTSW 11 59106316 missense probably damaging 1.00
R6959:Obscn UTSW 11 59037585 missense probably damaging 1.00
R7000:Obscn UTSW 11 59136038 missense probably damaging 1.00
R7028:Obscn UTSW 11 59079133 missense probably damaging 1.00
R7037:Obscn UTSW 11 59043929 missense probably damaging 1.00
R7037:Obscn UTSW 11 59052604 missense probably damaging 0.98
R7056:Obscn UTSW 11 58996296 unclassified probably benign
R7112:Obscn UTSW 11 59029325 missense
R7121:Obscn UTSW 11 59013252 nonsense probably null
R7123:Obscn UTSW 11 59013651 missense probably benign
R7182:Obscn UTSW 11 59035101 missense probably damaging 0.99
R7199:Obscn UTSW 11 59012846 missense probably benign 0.09
R7209:Obscn UTSW 11 59085107 nonsense probably null
R7235:Obscn UTSW 11 59080840 missense probably damaging 0.98
R7247:Obscn UTSW 11 59103318 nonsense probably null
R7262:Obscn UTSW 11 59115889 missense probably damaging 0.99
R7269:Obscn UTSW 11 59043012 missense probably damaging 0.99
R7270:Obscn UTSW 11 59029486 missense
R7274:Obscn UTSW 11 59133227 missense probably damaging 1.00
R7312:Obscn UTSW 11 59055616 missense probably benign 0.00
R7313:Obscn UTSW 11 59007588 missense unknown
R7360:Obscn UTSW 11 59082359 missense probably damaging 1.00
R7380:Obscn UTSW 11 59056914 missense
R7389:Obscn UTSW 11 59036400 missense probably benign 0.02
R7417:Obscn UTSW 11 59129577 missense possibly damaging 0.93
R7432:Obscn UTSW 11 59028907 missense
R7456:Obscn UTSW 11 59008558 missense probably benign 0.01
R7459:Obscn UTSW 11 59131657 missense probably benign 0.00
R7463:Obscn UTSW 11 59122860 missense probably benign 0.02
R7478:Obscn UTSW 11 59093416 missense probably damaging 1.00
R7498:Obscn UTSW 11 59082713 missense probably damaging 1.00
R7502:Obscn UTSW 11 58994809 missense unknown
R7509:Obscn UTSW 11 59051629 missense probably benign 0.36
R7516:Obscn UTSW 11 59124590 nonsense probably null
R7545:Obscn UTSW 11 59038899 missense probably damaging 1.00
R7549:Obscn UTSW 11 59042838 critical splice donor site probably null
R7582:Obscn UTSW 11 59061427 nonsense probably null
R7607:Obscn UTSW 11 58998265 missense unknown
R7609:Obscn UTSW 11 59000299 missense unknown
R7647:Obscn UTSW 11 58997287 critical splice acceptor site probably null
R7650:Obscn UTSW 11 59060994 missense probably benign 0.01
R7673:Obscn UTSW 11 59027437 missense
R7743:Obscn UTSW 11 59099777 missense probably damaging 1.00
R7745:Obscn UTSW 11 59060855 missense probably damaging 1.00
R7823:Obscn UTSW 11 59107940 missense probably damaging 1.00
R7840:Obscn UTSW 11 59077950 missense possibly damaging 0.88
R7854:Obscn UTSW 11 59090712 missense probably benign 0.14
R7867:Obscn UTSW 11 59000826 missense unknown
R7874:Obscn UTSW 11 59133276 missense probably damaging 1.00
R7877:Obscn UTSW 11 59133762 missense probably damaging 1.00
R7883:Obscn UTSW 11 59070009 nonsense probably null
R7903:Obscn UTSW 11 59079116 missense probably benign 0.15
R7924:Obscn UTSW 11 59112555 missense probably benign 0.27
R7925:Obscn UTSW 11 59112555 missense probably benign 0.27
R7936:Obscn UTSW 11 59050508 missense possibly damaging 0.46
R7944:Obscn UTSW 11 59093409 missense probably damaging 1.00
R7945:Obscn UTSW 11 59093409 missense probably damaging 1.00
R7984:Obscn UTSW 11 59106325 missense possibly damaging 0.91
R8042:Obscn UTSW 11 59040317 missense possibly damaging 0.61
R8073:Obscn UTSW 11 59135690 missense probably benign 0.25
R8079:Obscn UTSW 11 59081905 missense possibly damaging 0.84
R8108:Obscn UTSW 11 59061634 missense probably benign 0.17
R8117:Obscn UTSW 11 59042154 missense possibly damaging 0.91
R8130:Obscn UTSW 11 59124613 missense probably damaging 1.00
R8135:Obscn UTSW 11 59031877 missense possibly damaging 0.60
R8175:Obscn UTSW 11 58995960 missense unknown
R8205:Obscn UTSW 11 59007871 missense unknown
R8211:Obscn UTSW 11 59115794 missense probably damaging 0.99
R8219:Obscn UTSW 11 59122748 missense probably benign 0.03
R8245:Obscn UTSW 11 59022240 missense
R8290:Obscn UTSW 11 59062710 missense probably damaging 1.00
R8290:Obscn UTSW 11 59124574 missense probably damaging 0.99
R8300:Obscn UTSW 11 59043070 missense probably benign 0.02
R8346:Obscn UTSW 11 59085181 missense possibly damaging 0.80
R8384:Obscn UTSW 11 59085109 missense probably damaging 0.98
R8390:Obscn UTSW 11 59002044 missense probably benign 0.03
R8396:Obscn UTSW 11 59003003 missense probably benign 0.03
R8443:Obscn UTSW 11 59038874 missense probably damaging 0.99
R8469:Obscn UTSW 11 59128237 missense probably damaging 1.00
R8503:Obscn UTSW 11 59000617 missense unknown
R8683:Obscn UTSW 11 59076879 missense probably benign 0.45
R8688:Obscn UTSW 11 59056083 missense probably damaging 1.00
R8711:Obscn UTSW 11 59061068 missense probably damaging 0.96
R8713:Obscn UTSW 11 59135966 missense probably benign 0.03
R8803:Obscn UTSW 11 59054403 missense probably benign
R8807:Obscn UTSW 11 59079644 missense probably damaging 0.99
R8812:Obscn UTSW 11 59035095 missense probably damaging 1.00
R8842:Obscn UTSW 11 59002035 missense possibly damaging 0.56
R8852:Obscn UTSW 11 59007614 missense unknown
R8860:Obscn UTSW 11 59007614 missense unknown
R8878:Obscn UTSW 11 58999812 missense unknown
R8902:Obscn UTSW 11 59135936 missense probably benign 0.03
R8905:Obscn UTSW 11 59069958 missense probably damaging 0.96
R8925:Obscn UTSW 11 59086869 missense possibly damaging 0.90
R8927:Obscn UTSW 11 59086869 missense possibly damaging 0.90
R8934:Obscn UTSW 11 58998259 critical splice donor site probably null
R8936:Obscn UTSW 11 59002032 missense probably benign 0.36
R8950:Obscn UTSW 11 59056183 missense probably damaging 0.99
R8952:Obscn UTSW 11 59136134 missense probably damaging 1.00
R8958:Obscn UTSW 11 59073332 missense probably damaging 0.99
R8960:Obscn UTSW 11 59031612 missense probably damaging 1.00
R8967:Obscn UTSW 11 59081914 missense probably benign 0.11
R8972:Obscn UTSW 11 59052616 missense probably benign 0.15
R8997:Obscn UTSW 11 59043803 intron probably benign
R9012:Obscn UTSW 11 59130597 missense probably benign 0.01
R9053:Obscn UTSW 11 59081810 missense probably benign 0.45
R9064:Obscn UTSW 11 59009109 missense
R9070:Obscn UTSW 11 59122631 missense probably damaging 1.00
R9082:Obscn UTSW 11 59012786 missense probably benign 0.05
R9090:Obscn UTSW 11 59115817 missense probably damaging 0.99
R9144:Obscn UTSW 11 59069277 missense possibly damaging 0.65
R9171:Obscn UTSW 11 59061503 missense possibly damaging 0.47
R9195:Obscn UTSW 11 59051214 missense probably damaging 1.00
R9211:Obscn UTSW 11 59135867 missense probably benign 0.00
R9243:Obscn UTSW 11 59132566 missense probably benign 0.01
R9271:Obscn UTSW 11 59115817 missense probably damaging 0.99
R9288:Obscn UTSW 11 59085223 missense probably benign 0.00
R9297:Obscn UTSW 11 59007533 missense unknown
R9309:Obscn UTSW 11 59052511 missense probably damaging 0.98
R9330:Obscn UTSW 11 59080221 missense possibly damaging 0.95
R9357:Obscn UTSW 11 59038766 missense probably damaging 1.00
R9360:Obscn UTSW 11 59082824 missense probably benign 0.04
R9365:Obscn UTSW 11 58994511 critical splice acceptor site probably null
R9374:Obscn UTSW 11 59031961 missense possibly damaging 0.90
R9388:Obscn UTSW 11 59052663 missense probably damaging 1.00
R9391:Obscn UTSW 11 59073582 missense probably damaging 1.00
R9395:Obscn UTSW 11 59056045 missense probably damaging 0.99
R9406:Obscn UTSW 11 59056979 missense
R9452:Obscn UTSW 11 59034136 critical splice donor site probably null
R9472:Obscn UTSW 11 59003669 missense
R9486:Obscn UTSW 11 59027446 missense
R9515:Obscn UTSW 11 59103514 missense probably benign 0.01
R9585:Obscn UTSW 11 59075005 missense probably benign 0.09
R9597:Obscn UTSW 11 59136183 missense probably benign 0.14
R9602:Obscn UTSW 11 59090559 missense probably damaging 0.99
R9630:Obscn UTSW 11 59052571 missense probably benign 0.16
R9632:Obscn UTSW 11 59052571 missense probably benign 0.16
R9635:Obscn UTSW 11 59081860 missense possibly damaging 0.77
R9710:Obscn UTSW 11 59052571 missense probably benign 0.16
R9750:Obscn UTSW 11 59133856 missense probably benign 0.22
R9757:Obscn UTSW 11 59001512 missense probably benign 0.04
R9779:Obscn UTSW 11 59135615 missense probably benign 0.19
R9788:Obscn UTSW 11 59078852 missense possibly damaging 0.68
R9802:Obscn UTSW 11 58994363 missense unknown
X0010:Obscn UTSW 11 58995553 unclassified probably benign
X0012:Obscn UTSW 11 59006776 missense unknown
X0021:Obscn UTSW 11 59077906 missense probably damaging 0.96
X0058:Obscn UTSW 11 59035968 missense probably damaging 1.00
X0061:Obscn UTSW 11 59077830 missense probably damaging 1.00
X0063:Obscn UTSW 11 59000056 missense unknown
X0067:Obscn UTSW 11 59131801 missense probably benign 0.19
Y4336:Obscn UTSW 11 59131646 missense possibly damaging 0.90
Y4337:Obscn UTSW 11 59131646 missense possibly damaging 0.90
Y4338:Obscn UTSW 11 59131646 missense possibly damaging 0.90
Y5407:Obscn UTSW 11 59021943 missense probably damaging 0.97
Z1176:Obscn UTSW 11 58994372 missense unknown
Z1176:Obscn UTSW 11 58995530 missense unknown
Z1176:Obscn UTSW 11 59038807 missense probably damaging 1.00
Z1176:Obscn UTSW 11 59040347 missense probably benign 0.39
Z1176:Obscn UTSW 11 59049725 missense probably benign 0.01
Z1176:Obscn UTSW 11 59082823 missense probably benign 0.25
Z1176:Obscn UTSW 11 59136286 missense probably benign 0.39
Z1177:Obscn UTSW 11 59000955 missense probably benign 0.04
Z1177:Obscn UTSW 11 59010444 missense
Z1177:Obscn UTSW 11 59051543 missense probably damaging 0.98
Z1177:Obscn UTSW 11 59055490 missense probably damaging 1.00
Z1177:Obscn UTSW 11 59056039 missense probably damaging 1.00
Z1177:Obscn UTSW 11 59061015 missense possibly damaging 0.68
Z1177:Obscn UTSW 11 59062087 missense probably damaging 1.00
Z1177:Obscn UTSW 11 59062887 missense probably damaging 1.00
Z1177:Obscn UTSW 11 59135466 missense possibly damaging 0.50
Z1186:Obscn UTSW 11 59000889 missense probably benign 0.35
Z1186:Obscn UTSW 11 59009193 missense probably benign 0.01
Z1186:Obscn UTSW 11 59013188 missense probably benign 0.07
Z1186:Obscn UTSW 11 59031108 missense probably damaging 0.97
Z1186:Obscn UTSW 11 59039150 missense probably benign 0.43
Z1186:Obscn UTSW 11 59039164 missense probably damaging 0.97
Z1186:Obscn UTSW 11 59041775 missense probably benign 0.00
Z1186:Obscn UTSW 11 59042950 missense probably benign 0.00
Z1186:Obscn UTSW 11 59043027 missense probably benign 0.13
Z1186:Obscn UTSW 11 59043052 missense probably benign 0.00
Z1186:Obscn UTSW 11 59049480 missense
Z1186:Obscn UTSW 11 59049788 missense possibly damaging 0.89
Z1186:Obscn UTSW 11 59049797 missense
Z1186:Obscn UTSW 11 59051557 missense probably benign 0.11
Z1186:Obscn UTSW 11 59052613 missense probably benign 0.01
Z1186:Obscn UTSW 11 59053768 missense probably benign 0.00
Z1186:Obscn UTSW 11 59053825 missense probably benign
Z1186:Obscn UTSW 11 59054218 missense probably benign
Z1186:Obscn UTSW 11 59054350 missense probably benign 0.00
Z1186:Obscn UTSW 11 59055505 missense probably damaging 0.99
Z1186:Obscn UTSW 11 59055514 missense probably benign 0.00
Z1186:Obscn UTSW 11 59056110 missense possibly damaging 0.85
Z1186:Obscn UTSW 11 59056769 missense
Z1186:Obscn UTSW 11 59061562 missense probably benign 0.01
Z1186:Obscn UTSW 11 59063453 frame shift probably null
Z1186:Obscn UTSW 11 59063474 missense
Z1186:Obscn UTSW 11 59063576 missense probably damaging 1.00
Z1186:Obscn UTSW 11 59067147 missense probably benign 0.00
Z1186:Obscn UTSW 11 59067829 missense probably benign 0.01
Z1186:Obscn UTSW 11 59069931 missense probably benign 0.00
Z1186:Obscn UTSW 11 59076508 missense possibly damaging 0.71
Z1186:Obscn UTSW 11 59079158 missense probably damaging 1.00
Z1186:Obscn UTSW 11 59079896 missense probably benign 0.00
Z1186:Obscn UTSW 11 59081872 missense possibly damaging 0.96
Z1186:Obscn UTSW 11 59086679 missense probably benign 0.04
Z1186:Obscn UTSW 11 59086701 missense probably benign
Z1186:Obscn UTSW 11 59086739 missense probably benign 0.00
Z1186:Obscn UTSW 11 59093316 missense probably benign
Z1186:Obscn UTSW 11 59093413 missense possibly damaging 0.82
Z1186:Obscn UTSW 11 59093508 missense possibly damaging 0.95
Z1186:Obscn UTSW 11 59093509 missense probably benign 0.29
Z1186:Obscn UTSW 11 59093559 missense probably benign 0.00
Z1186:Obscn UTSW 11 59099909 missense possibly damaging 0.66
Z1186:Obscn UTSW 11 59099929 missense probably benign 0.00
Z1186:Obscn UTSW 11 59103341 missense probably damaging 1.00
Z1186:Obscn UTSW 11 59103514 missense probably benign 0.00
Z1186:Obscn UTSW 11 59103538 missense probably benign 0.00
Z1186:Obscn UTSW 11 59112554 missense probably benign 0.00
Z1186:Obscn UTSW 11 59122737 missense probably benign 0.01
Z1186:Obscn UTSW 11 59128066 missense probably benign 0.06
Z1186:Obscn UTSW 11 59128069 missense probably damaging 0.99
Z1186:Obscn UTSW 11 59130623 missense probably damaging 0.98
Z1186:Obscn UTSW 11 59133111 missense possibly damaging 0.48
Z1186:Obscn UTSW 11 59133240 missense probably damaging 1.00
Z1186:Obscn UTSW 11 59133246 missense probably benign 0.01
Z1186:Obscn UTSW 11 59135679 missense probably benign 0.05
Z1187:Obscn UTSW 11 59000889 missense probably benign 0.35
Z1187:Obscn UTSW 11 59009193 missense probably benign 0.01
Z1187:Obscn UTSW 11 59013188 missense probably benign 0.07
Z1187:Obscn UTSW 11 59031108 missense probably damaging 0.97
Z1187:Obscn UTSW 11 59039150 missense probably benign 0.43
Z1187:Obscn UTSW 11 59039164 missense probably damaging 0.97
Z1187:Obscn UTSW 11 59041775 missense probably benign 0.00
Z1187:Obscn UTSW 11 59042950 missense probably benign 0.00
Z1187:Obscn UTSW 11 59043027 missense probably benign 0.13
Z1187:Obscn UTSW 11 59043052 missense probably benign 0.00
Z1187:Obscn UTSW 11 59049480 missense
Z1187:Obscn UTSW 11 59049788 missense possibly damaging 0.89
Z1187:Obscn UTSW 11 59049797 missense
Z1187:Obscn UTSW 11 59051557 missense probably benign 0.11
Z1187:Obscn UTSW 11 59052613 missense probably benign 0.01
Z1187:Obscn UTSW 11 59053768 missense probably benign 0.00
Z1187:Obscn UTSW 11 59053825 missense probably benign
Z1187:Obscn UTSW 11 59054218 missense probably benign
Z1187:Obscn UTSW 11 59054350 missense probably benign 0.00
Z1187:Obscn UTSW 11 59055505 missense probably damaging 0.99
Z1187:Obscn UTSW 11 59055514 missense probably benign 0.00
Z1187:Obscn UTSW 11 59056110 missense possibly damaging 0.85
Z1187:Obscn UTSW 11 59056769 missense
Z1187:Obscn UTSW 11 59060997 missense probably damaging 1.00
Z1187:Obscn UTSW 11 59061562 missense probably benign 0.01
Z1187:Obscn UTSW 11 59063453 frame shift probably null
Z1187:Obscn UTSW 11 59063474 missense
Z1187:Obscn UTSW 11 59063576 missense probably damaging 1.00
Z1187:Obscn UTSW 11 59067147 missense probably benign 0.00
Z1187:Obscn UTSW 11 59067829 missense probably benign 0.01
Z1187:Obscn UTSW 11 59069833 synonymous silent
Z1187:Obscn UTSW 11 59069931 missense probably benign 0.00
Z1187:Obscn UTSW 11 59076508 missense possibly damaging 0.71
Z1187:Obscn UTSW 11 59079158 missense probably damaging 1.00
Z1187:Obscn UTSW 11 59079896 missense probably benign 0.00
Z1187:Obscn UTSW 11 59081872 missense possibly damaging 0.96
Z1187:Obscn UTSW 11 59086679 missense probably benign 0.04
Z1187:Obscn UTSW 11 59086701 missense probably benign
Z1187:Obscn UTSW 11 59086739 missense probably benign 0.00
Z1187:Obscn UTSW 11 59093316 missense probably benign
Z1187:Obscn UTSW 11 59093413 missense possibly damaging 0.82
Z1187:Obscn UTSW 11 59093508 missense possibly damaging 0.95
Z1187:Obscn UTSW 11 59093509 missense probably benign 0.29
Z1187:Obscn UTSW 11 59093559 missense probably benign 0.00
Z1187:Obscn UTSW 11 59099909 missense possibly damaging 0.66
Z1187:Obscn UTSW 11 59099929 missense probably benign 0.00
Z1187:Obscn UTSW 11 59103341 missense probably damaging 1.00
Z1187:Obscn UTSW 11 59103514 missense probably benign 0.00
Z1187:Obscn UTSW 11 59103538 missense probably benign 0.00
Z1187:Obscn UTSW 11 59112554 missense probably benign 0.00
Z1187:Obscn UTSW 11 59122737 missense probably benign 0.01
Z1187:Obscn UTSW 11 59128066 missense probably benign 0.06
Z1187:Obscn UTSW 11 59128069 missense probably damaging 0.99
Z1187:Obscn UTSW 11 59129837 missense probably benign 0.11
Z1187:Obscn UTSW 11 59130623 missense probably damaging 0.98
Z1187:Obscn UTSW 11 59133111 missense possibly damaging 0.48
Z1187:Obscn UTSW 11 59133240 missense probably damaging 1.00
Z1187:Obscn UTSW 11 59133246 missense probably benign 0.01
Z1187:Obscn UTSW 11 59135679 missense probably benign 0.05
Z1188:Obscn UTSW 11 59000889 missense probably benign 0.35
Z1188:Obscn UTSW 11 59009193 missense probably benign 0.01
Z1188:Obscn UTSW 11 59013188 missense probably benign 0.07
Z1188:Obscn UTSW 11 59031108 missense probably damaging 0.97
Z1188:Obscn UTSW 11 59039150 missense probably benign 0.43
Z1188:Obscn UTSW 11 59039164 missense probably damaging 0.97
Z1188:Obscn UTSW 11 59041775 missense probably benign 0.00
Z1188:Obscn UTSW 11 59042950 missense probably benign 0.00
Z1188:Obscn UTSW 11 59043027 missense probably benign 0.13
Z1188:Obscn UTSW 11 59043052 missense probably benign 0.00
Z1188:Obscn UTSW 11 59049480 missense
Z1188:Obscn UTSW 11 59049788 missense possibly damaging 0.89
Z1188:Obscn UTSW 11 59049797 missense
Z1188:Obscn UTSW 11 59051557 missense probably benign 0.11
Z1188:Obscn UTSW 11 59052613 missense probably benign 0.01
Z1188:Obscn UTSW 11 59053768 missense probably benign 0.00
Z1188:Obscn UTSW 11 59053825 missense probably benign
Z1188:Obscn UTSW 11 59054218 missense probably benign
Z1188:Obscn UTSW 11 59054350 missense probably benign 0.00
Z1188:Obscn UTSW 11 59054834 missense probably benign 0.04
Z1188:Obscn UTSW 11 59055457 missense probably damaging 1.00
Z1188:Obscn UTSW 11 59055505 missense probably damaging 0.99
Z1188:Obscn UTSW 11 59055514 missense probably benign 0.00
Z1188:Obscn UTSW 11 59056110 missense possibly damaging 0.85
Z1188:Obscn UTSW 11 59056769 missense
Z1188:Obscn UTSW 11 59060997 missense probably damaging 1.00
Z1188:Obscn UTSW 11 59061562 missense probably benign 0.01
Z1188:Obscn UTSW 11 59061582 missense probably benign 0.37
Z1188:Obscn UTSW 11 59062133 missense probably benign
Z1188:Obscn UTSW 11 59062139 missense probably damaging 0.97
Z1188:Obscn UTSW 11 59063453 frame shift probably null
Z1188:Obscn UTSW 11 59063474 missense
Z1188:Obscn UTSW 11 59063576 missense probably damaging 1.00
Z1188:Obscn UTSW 11 59067147 missense probably benign 0.00
Z1188:Obscn UTSW 11 59067829 missense probably benign 0.01
Z1188:Obscn UTSW 11 59069931 missense probably benign 0.00
Z1188:Obscn UTSW 11 59076508 missense possibly damaging 0.71
Z1188:Obscn UTSW 11 59079158 missense probably damaging 1.00
Z1188:Obscn UTSW 11 59079896 missense probably benign 0.00
Z1188:Obscn UTSW 11 59081872 missense possibly damaging 0.96
Z1188:Obscn UTSW 11 59086679 missense probably benign 0.04
Z1188:Obscn UTSW 11 59086701 missense probably benign
Z1188:Obscn UTSW 11 59086739 missense probably benign 0.00
Z1188:Obscn UTSW 11 59090747 missense probably benign
Z1188:Obscn UTSW 11 59093316 missense probably benign
Z1188:Obscn UTSW 11 59093413 missense possibly damaging 0.82
Z1188:Obscn UTSW 11 59093508 missense possibly damaging 0.95
Z1188:Obscn UTSW 11 59093509 missense probably benign 0.29
Z1188:Obscn UTSW 11 59093559 missense probably benign 0.00
Z1188:Obscn UTSW 11 59099909 missense possibly damaging 0.66
Z1188:Obscn UTSW 11 59099929 missense probably benign 0.00
Z1188:Obscn UTSW 11 59103341 missense probably damaging 1.00
Z1188:Obscn UTSW 11 59103514 missense probably benign 0.00
Z1188:Obscn UTSW 11 59103538 missense probably benign 0.00
Z1188:Obscn UTSW 11 59112554 missense probably benign 0.00
Z1188:Obscn UTSW 11 59112636 missense probably benign 0.01
Z1188:Obscn UTSW 11 59122737 missense probably benign 0.01
Z1188:Obscn UTSW 11 59128066 missense probably benign 0.06
Z1188:Obscn UTSW 11 59128069 missense probably damaging 0.99
Z1188:Obscn UTSW 11 59129687 missense probably benign 0.00
Z1188:Obscn UTSW 11 59129837 missense probably benign 0.11
Z1188:Obscn UTSW 11 59130623 missense probably damaging 0.98
Z1188:Obscn UTSW 11 59133111 missense possibly damaging 0.48
Z1188:Obscn UTSW 11 59133240 missense probably damaging 1.00
Z1188:Obscn UTSW 11 59133246 missense probably benign 0.01
Z1188:Obscn UTSW 11 59135679 missense probably benign 0.05
Z1189:Obscn UTSW 11 59000889 missense probably benign 0.35
Z1189:Obscn UTSW 11 59009193 missense probably benign 0.01
Z1189:Obscn UTSW 11 59013188 missense probably benign 0.07
Z1189:Obscn UTSW 11 59031108 missense probably damaging 0.97
Z1189:Obscn UTSW 11 59039150 missense probably benign 0.43
Z1189:Obscn UTSW 11 59039164 missense probably damaging 0.97
Z1189:Obscn UTSW 11 59042950 missense probably benign 0.00
Z1189:Obscn UTSW 11 59043027 missense probably benign 0.13
Z1189:Obscn UTSW 11 59043052 missense probably benign 0.00
Z1189:Obscn UTSW 11 59049480 missense
Z1189:Obscn UTSW 11 59049788 missense possibly damaging 0.89
Z1189:Obscn UTSW 11 59049797 missense
Z1189:Obscn UTSW 11 59051557 missense probably benign 0.11
Z1189:Obscn UTSW 11 59052613 missense probably benign 0.01
Z1189:Obscn UTSW 11 59053768 missense probably benign 0.00
Z1189:Obscn UTSW 11 59053825 missense probably benign
Z1189:Obscn UTSW 11 59054218 missense probably benign
Z1189:Obscn UTSW 11 59054350 missense probably benign 0.00
Z1189:Obscn UTSW 11 59055505 missense probably damaging 0.99
Z1189:Obscn UTSW 11 59056110 missense possibly damaging 0.85
Z1189:Obscn UTSW 11 59056769 missense
Z1189:Obscn UTSW 11 59063474 missense
Z1189:Obscn UTSW 11 59063576 missense probably damaging 1.00
Z1189:Obscn UTSW 11 59067147 missense probably benign 0.00
Z1189:Obscn UTSW 11 59067829 missense probably benign 0.01
Z1189:Obscn UTSW 11 59069931 missense probably benign 0.00
Z1189:Obscn UTSW 11 59076508 missense possibly damaging 0.71
Z1189:Obscn UTSW 11 59079158 missense probably damaging 1.00
Z1189:Obscn UTSW 11 59079896 missense probably benign 0.00
Z1189:Obscn UTSW 11 59081872 missense possibly damaging 0.96
Z1189:Obscn UTSW 11 59086679 missense probably benign 0.04
Z1189:Obscn UTSW 11 59086701 missense probably benign
Z1189:Obscn UTSW 11 59093316 missense probably benign
Z1189:Obscn UTSW 11 59093413 missense possibly damaging 0.82
Z1189:Obscn UTSW 11 59093508 missense possibly damaging 0.95
Z1189:Obscn UTSW 11 59093509 missense probably benign 0.29
Z1189:Obscn UTSW 11 59093559 missense probably benign 0.00
Z1189:Obscn UTSW 11 59103341 missense probably damaging 1.00
Z1189:Obscn UTSW 11 59103538 missense probably benign 0.00
Z1189:Obscn UTSW 11 59112554 missense probably benign 0.00
Z1189:Obscn UTSW 11 59122737 missense probably benign 0.01
Z1189:Obscn UTSW 11 59130623 missense probably damaging 0.98
Z1189:Obscn UTSW 11 59133111 missense possibly damaging 0.48
Z1189:Obscn UTSW 11 59133240 missense probably damaging 1.00
Z1189:Obscn UTSW 11 59133246 missense probably benign 0.01
Z1189:Obscn UTSW 11 59135679 missense probably benign 0.05
Z1190:Obscn UTSW 11 59000889 missense probably benign 0.35
Z1190:Obscn UTSW 11 59009193 missense probably benign 0.01
Z1190:Obscn UTSW 11 59013188 missense probably benign 0.07
Z1190:Obscn UTSW 11 59031108 missense probably damaging 0.97
Z1190:Obscn UTSW 11 59039150 missense probably benign 0.43
Z1190:Obscn UTSW 11 59039164 missense probably damaging 0.97
Z1190:Obscn UTSW 11 59042950 missense probably benign 0.00
Z1190:Obscn UTSW 11 59043027 missense probably benign 0.13
Z1190:Obscn UTSW 11 59043052 missense probably benign 0.00
Z1190:Obscn UTSW 11 59049480 missense
Z1190:Obscn UTSW 11 59049788 missense possibly damaging 0.89
Z1190:Obscn UTSW 11 59049797 missense
Z1190:Obscn UTSW 11 59051557 missense probably benign 0.11
Z1190:Obscn UTSW 11 59052613 missense probably benign 0.01
Z1190:Obscn UTSW 11 59053768 missense probably benign 0.00
Z1190:Obscn UTSW 11 59053825 missense probably benign
Z1190:Obscn UTSW 11 59054218 missense probably benign
Z1190:Obscn UTSW 11 59054350 missense probably benign 0.00
Z1190:Obscn UTSW 11 59054834 missense probably benign 0.04
Z1190:Obscn UTSW 11 59055457 missense probably damaging 1.00
Z1190:Obscn UTSW 11 59055505 missense probably damaging 0.99
Z1190:Obscn UTSW 11 59055514 missense probably benign 0.00
Z1190:Obscn UTSW 11 59056110 missense possibly damaging 0.85
Z1190:Obscn UTSW 11 59056769 missense
Z1190:Obscn UTSW 11 59060997 missense probably damaging 1.00
Z1190:Obscn UTSW 11 59061562 missense probably benign 0.01
Z1190:Obscn UTSW 11 59061582 missense probably benign 0.37
Z1190:Obscn UTSW 11 59062139 missense probably damaging 0.97
Z1190:Obscn UTSW 11 59063453 frame shift probably null
Z1190:Obscn UTSW 11 59063474 missense
Z1190:Obscn UTSW 11 59063576 missense probably damaging 1.00
Z1190:Obscn UTSW 11 59067147 missense probably benign 0.00
Z1190:Obscn UTSW 11 59067829 missense probably benign 0.01
Z1190:Obscn UTSW 11 59069931 missense probably benign 0.00
Z1190:Obscn UTSW 11 59076508 missense possibly damaging 0.71
Z1190:Obscn UTSW 11 59079158 missense probably damaging 1.00
Z1190:Obscn UTSW 11 59079896 missense probably benign 0.00
Z1190:Obscn UTSW 11 59081872 missense possibly damaging 0.96
Z1190:Obscn UTSW 11 59086679 missense probably benign 0.04
Z1190:Obscn UTSW 11 59086701 missense probably benign
Z1190:Obscn UTSW 11 59086739 missense probably benign 0.00
Z1190:Obscn UTSW 11 59086929 missense probably benign 0.15
Z1190:Obscn UTSW 11 59093316 missense probably benign
Z1190:Obscn UTSW 11 59093413 missense possibly damaging 0.82
Z1190:Obscn UTSW 11 59093508 missense possibly damaging 0.95
Z1190:Obscn UTSW 11 59093509 missense probably benign 0.29
Z1190:Obscn UTSW 11 59093559 missense probably benign 0.00
Z1190:Obscn UTSW 11 59099909 missense possibly damaging 0.66
Z1190:Obscn UTSW 11 59099929 missense probably benign 0.00
Z1190:Obscn UTSW 11 59103341 missense probably damaging 1.00
Z1190:Obscn UTSW 11 59103514 missense probably benign 0.00
Z1190:Obscn UTSW 11 59103538 missense probably benign 0.00
Z1190:Obscn UTSW 11 59112554 missense probably benign 0.00
Z1190:Obscn UTSW 11 59122737 missense probably benign 0.01
Z1190:Obscn UTSW 11 59122838 missense probably benign
Z1190:Obscn UTSW 11 59128066 missense probably benign 0.06
Z1190:Obscn UTSW 11 59128069 missense probably damaging 0.99
Z1190:Obscn UTSW 11 59129837 missense probably benign 0.11
Z1190:Obscn UTSW 11 59130623 missense probably damaging 0.98
Z1190:Obscn UTSW 11 59133111 missense possibly damaging 0.48
Z1190:Obscn UTSW 11 59133240 missense probably damaging 1.00
Z1190:Obscn UTSW 11 59133246 missense probably benign 0.01
Z1190:Obscn UTSW 11 59135679 missense probably benign 0.05
Z1191:Obscn UTSW 11 59000889 missense probably benign 0.35
Z1191:Obscn UTSW 11 59009193 missense probably benign 0.01
Z1191:Obscn UTSW 11 59013188 missense probably benign 0.07
Z1191:Obscn UTSW 11 59031108 missense probably damaging 0.97
Z1191:Obscn UTSW 11 59039150 missense probably benign 0.43
Z1191:Obscn UTSW 11 59039164 missense probably damaging 0.97
Z1191:Obscn UTSW 11 59041775 missense probably benign 0.00
Z1191:Obscn UTSW 11 59041848 critical splice acceptor site probably null
Z1191:Obscn UTSW 11 59042950 missense probably benign 0.00
Z1191:Obscn UTSW 11 59043027 missense probably benign 0.13
Z1191:Obscn UTSW 11 59043052 missense probably benign 0.00
Z1191:Obscn UTSW 11 59049480 missense
Z1191:Obscn UTSW 11 59049788 missense possibly damaging 0.89
Z1191:Obscn UTSW 11 59049797 missense
Z1191:Obscn UTSW 11 59051557 missense probably benign 0.11
Z1191:Obscn UTSW 11 59052613 missense probably benign 0.01
Z1191:Obscn UTSW 11 59053768 missense probably benign 0.00
Z1191:Obscn UTSW 11 59053825 missense probably benign
Z1191:Obscn UTSW 11 59054218 missense probably benign
Z1191:Obscn UTSW 11 59054350 missense probably benign 0.00
Z1191:Obscn UTSW 11 59054834 missense probably benign 0.04
Z1191:Obscn UTSW 11 59055457 missense probably damaging 1.00
Z1191:Obscn UTSW 11 59055505 missense probably damaging 0.99
Z1191:Obscn UTSW 11 59055514 missense probably benign 0.00
Z1191:Obscn UTSW 11 59056110 missense possibly damaging 0.85
Z1191:Obscn UTSW 11 59056769 missense
Z1191:Obscn UTSW 11 59060997 missense probably damaging 1.00
Z1191:Obscn UTSW 11 59061562 missense probably benign 0.01
Z1191:Obscn UTSW 11 59061582 missense probably benign 0.37
Z1191:Obscn UTSW 11 59062133 missense probably benign
Z1191:Obscn UTSW 11 59062139 missense probably damaging 0.97
Z1191:Obscn UTSW 11 59063453 frame shift probably null
Z1191:Obscn UTSW 11 59063474 missense
Z1191:Obscn UTSW 11 59063576 missense probably damaging 1.00
Z1191:Obscn UTSW 11 59067147 missense probably benign 0.00
Z1191:Obscn UTSW 11 59067829 missense probably benign 0.01
Z1191:Obscn UTSW 11 59069931 missense probably benign 0.00
Z1191:Obscn UTSW 11 59076508 missense possibly damaging 0.71
Z1191:Obscn UTSW 11 59079158 missense probably damaging 1.00
Z1191:Obscn UTSW 11 59079896 missense probably benign 0.00
Z1191:Obscn UTSW 11 59081872 missense possibly damaging 0.96
Z1191:Obscn UTSW 11 59086679 missense probably benign 0.04
Z1191:Obscn UTSW 11 59086701 missense probably benign
Z1191:Obscn UTSW 11 59086739 missense probably benign 0.00
Z1191:Obscn UTSW 11 59090747 missense probably benign
Z1191:Obscn UTSW 11 59093316 missense probably benign
Z1191:Obscn UTSW 11 59093413 missense possibly damaging 0.82
Z1191:Obscn UTSW 11 59093508 missense possibly damaging 0.95
Z1191:Obscn UTSW 11 59093509 missense probably benign 0.29
Z1191:Obscn UTSW 11 59093559 missense probably benign 0.00
Z1191:Obscn UTSW 11 59099909 missense possibly damaging 0.66
Z1191:Obscn UTSW 11 59099929 missense probably benign 0.00
Z1191:Obscn UTSW 11 59103341 missense probably damaging 1.00
Z1191:Obscn UTSW 11 59103514 missense probably benign 0.00
Z1191:Obscn UTSW 11 59103538 missense probably benign 0.00
Z1191:Obscn UTSW 11 59112554 missense probably benign 0.00
Z1191:Obscn UTSW 11 59112636 missense probably benign 0.01
Z1191:Obscn UTSW 11 59122737 missense probably benign 0.01
Z1191:Obscn UTSW 11 59122838 missense probably benign
Z1191:Obscn UTSW 11 59128066 missense probably benign 0.06
Z1191:Obscn UTSW 11 59128069 missense probably damaging 0.99
Z1191:Obscn UTSW 11 59128249 missense probably damaging 1.00
Z1191:Obscn UTSW 11 59129687 missense probably benign 0.00
Z1191:Obscn UTSW 11 59129837 missense probably benign 0.11
Z1191:Obscn UTSW 11 59130623 missense probably damaging 0.98
Z1191:Obscn UTSW 11 59133111 missense possibly damaging 0.48
Z1191:Obscn UTSW 11 59133240 missense probably damaging 1.00
Z1191:Obscn UTSW 11 59133246 missense probably benign 0.01
Z1191:Obscn UTSW 11 59135679 missense probably benign 0.05
Z1192:Obscn UTSW 11 59000889 missense probably benign 0.35
Z1192:Obscn UTSW 11 59009193 missense probably benign 0.01
Z1192:Obscn UTSW 11 59013188 missense probably benign 0.07
Z1192:Obscn UTSW 11 59031108 missense probably damaging 0.97
Z1192:Obscn UTSW 11 59039150 missense probably benign 0.43
Z1192:Obscn UTSW 11 59039164 missense probably damaging 0.97
Z1192:Obscn UTSW 11 59041775 missense probably benign 0.00
Z1192:Obscn UTSW 11 59042950 missense probably benign 0.00
Z1192:Obscn UTSW 11 59043027 missense probably benign 0.13
Z1192:Obscn UTSW 11 59043052 missense probably benign 0.00
Z1192:Obscn UTSW 11 59049480 missense
Z1192:Obscn UTSW 11 59049788 missense possibly damaging 0.89
Z1192:Obscn UTSW 11 59049797 missense
Z1192:Obscn UTSW 11 59051557 missense probably benign 0.11
Z1192:Obscn UTSW 11 59052613 missense probably benign 0.01
Z1192:Obscn UTSW 11 59053768 missense probably benign 0.00
Z1192:Obscn UTSW 11 59053825 missense probably benign
Z1192:Obscn UTSW 11 59054218 missense probably benign
Z1192:Obscn UTSW 11 59054350 missense probably benign 0.00
Z1192:Obscn UTSW 11 59055505 missense probably damaging 0.99
Z1192:Obscn UTSW 11 59055514 missense probably benign 0.00
Z1192:Obscn UTSW 11 59056110 missense possibly damaging 0.85
Z1192:Obscn UTSW 11 59056769 missense
Z1192:Obscn UTSW 11 59061562 missense probably benign 0.01
Z1192:Obscn UTSW 11 59063576 missense probably damaging 1.00
Z1192:Obscn UTSW 11 59067147 missense probably benign 0.00
Z1192:Obscn UTSW 11 59067829 missense probably benign 0.01
Z1192:Obscn UTSW 11 59069931 missense probably benign 0.00
Z1192:Obscn UTSW 11 59076508 missense possibly damaging 0.71
Z1192:Obscn UTSW 11 59079158 missense probably damaging 1.00
Z1192:Obscn UTSW 11 59079896 missense probably benign 0.00
Z1192:Obscn UTSW 11 59081872 missense possibly damaging 0.96
Z1192:Obscn UTSW 11 59086679 missense probably benign 0.04
Z1192:Obscn UTSW 11 59086701 missense probably benign
Z1192:Obscn UTSW 11 59086739 missense probably benign 0.00
Z1192:Obscn UTSW 11 59093316 missense probably benign
Z1192:Obscn UTSW 11 59093413 missense possibly damaging 0.82
Z1192:Obscn UTSW 11 59093508 missense possibly damaging 0.95
Z1192:Obscn UTSW 11 59093509 missense probably benign 0.29
Z1192:Obscn UTSW 11 59093559 missense probably benign 0.00
Z1192:Obscn UTSW 11 59099909 missense possibly damaging 0.66
Z1192:Obscn UTSW 11 59099929 missense probably benign 0.00
Z1192:Obscn UTSW 11 59103341 missense probably damaging 1.00
Z1192:Obscn UTSW 11 59103538 missense probably benign 0.00
Z1192:Obscn UTSW 11 59112554 missense probably benign 0.00
Z1192:Obscn UTSW 11 59122737 missense probably benign 0.01
Z1192:Obscn UTSW 11 59128066 missense probably benign 0.06
Z1192:Obscn UTSW 11 59128069 missense probably damaging 0.99
Z1192:Obscn UTSW 11 59130623 missense probably damaging 0.98
Z1192:Obscn UTSW 11 59133111 missense possibly damaging 0.48
Z1192:Obscn UTSW 11 59133240 missense probably damaging 1.00
Z1192:Obscn UTSW 11 59133246 missense probably benign 0.01
Z1192:Obscn UTSW 11 59135679 missense probably benign 0.05
Predicted Primers PCR Primer
(F):5'- GCCCAAGTGAATAGAGCCAAGC -3'
(R):5'- TGCTAGGATACCCATTCTACCTG -3'

Sequencing Primer
(F):5'- TGGCCCTAGTGAGAGGCTG -3'
(R):5'- GCCTTGGGCCTGTTCTGAAC -3'
Posted On 2019-09-13