Incidental Mutation 'R7404:Dnah7c'
| ID |
574387 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dnah7c
|
| Ensembl Gene |
ENSMUSG00000101337 |
| Gene Name |
dynein, axonemal, heavy chain 7C |
| Synonyms |
Dnahc7c |
| MMRRC Submission |
045486-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.340)
|
| Stock # |
R7404 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
46464752-46846636 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 46705223 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 2412
(V2412A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000140430
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000189749]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000189749
AA Change: V2412A
PolyPhen 2
Score 0.516 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000140430
Gene: ENSMUSG00000101337
AA Change: V2412A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
15 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
714 |
746 |
N/A |
INTRINSIC |
|
Pfam:DHC_N2
|
754 |
1167 |
2.2e-138 |
PFAM |
|
AAA
|
1320 |
1459 |
4e-3 |
SMART |
|
Blast:AAA
|
1601 |
1829 |
4e-87 |
BLAST |
|
AAA
|
1968 |
2116 |
8.7e-4 |
SMART |
|
Pfam:AAA_8
|
2303 |
2574 |
6.2e-73 |
PFAM |
|
Pfam:MT
|
2586 |
2935 |
5.4e-52 |
PFAM |
|
Pfam:AAA_9
|
2953 |
3183 |
7.4e-63 |
PFAM |
|
Pfam:Dynein_heavy
|
3312 |
4021 |
1.3e-250 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
99% (92/93) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ablim3 |
C |
T |
18: 61,955,099 (GRCm39) |
A297T |
probably damaging |
Het |
| Adprhl1 |
T |
A |
8: 13,275,118 (GRCm39) |
S547C |
probably damaging |
Het |
| Ankrd63 |
G |
C |
2: 118,533,793 (GRCm39) |
R43G |
unknown |
Het |
| Asah2 |
T |
C |
19: 32,035,254 (GRCm39) |
T24A |
probably benign |
Het |
| Asb17 |
G |
A |
3: 153,550,447 (GRCm39) |
|
probably null |
Het |
| Atp8b5 |
C |
T |
4: 43,342,640 (GRCm39) |
T437I |
probably benign |
Het |
| Bbs2 |
T |
C |
8: 94,808,992 (GRCm39) |
D311G |
probably damaging |
Het |
| Birc6 |
C |
T |
17: 74,946,789 (GRCm39) |
T2851I |
possibly damaging |
Het |
| Bnip5 |
G |
A |
17: 29,124,298 (GRCm39) |
R335W |
probably damaging |
Het |
| Cchcr1 |
T |
C |
17: 35,835,693 (GRCm39) |
W266R |
probably benign |
Het |
| Col14a1 |
C |
A |
15: 55,252,024 (GRCm39) |
S560* |
probably null |
Het |
| Crocc |
G |
A |
4: 140,753,497 (GRCm39) |
T1317M |
possibly damaging |
Het |
| Cxxc1 |
T |
A |
18: 74,352,278 (GRCm39) |
V334E |
possibly damaging |
Het |
| Cyp3a25 |
T |
A |
5: 145,923,635 (GRCm39) |
D336V |
probably damaging |
Het |
| Dapk1 |
A |
G |
13: 60,867,455 (GRCm39) |
T221A |
probably benign |
Het |
| Dnah11 |
G |
T |
12: 118,068,543 (GRCm39) |
T1605K |
probably benign |
Het |
| Ect2l |
T |
A |
10: 18,035,529 (GRCm39) |
D524V |
probably damaging |
Het |
| Ehbp1l1 |
T |
C |
19: 5,770,872 (GRCm39) |
E223G |
possibly damaging |
Het |
| Ephb2 |
A |
T |
4: 136,498,524 (GRCm39) |
M185K |
probably damaging |
Het |
| Fcer1a |
T |
C |
1: 173,049,083 (GRCm39) |
K243E |
probably damaging |
Het |
| Fcgbp |
T |
A |
7: 27,800,932 (GRCm39) |
I1326N |
probably damaging |
Het |
| Fgfr1 |
T |
C |
8: 26,045,566 (GRCm39) |
V45A |
probably benign |
Het |
| Filip1 |
T |
A |
9: 79,727,380 (GRCm39) |
E413V |
possibly damaging |
Het |
| Frs3 |
T |
C |
17: 48,013,651 (GRCm39) |
|
probably null |
Het |
| Fstl4 |
A |
G |
11: 53,024,898 (GRCm39) |
T257A |
probably benign |
Het |
| Golga5 |
A |
T |
12: 102,450,778 (GRCm39) |
K477M |
probably damaging |
Het |
| Gpr171 |
A |
T |
3: 59,005,622 (GRCm39) |
I51K |
probably damaging |
Het |
| H1f0 |
T |
A |
15: 78,913,080 (GRCm39) |
Y53* |
probably null |
Het |
| Hephl1 |
A |
G |
9: 14,981,047 (GRCm39) |
V795A |
possibly damaging |
Het |
| Hmcn1 |
A |
T |
1: 150,596,510 (GRCm39) |
D1775E |
probably benign |
Het |
| Hs3st2 |
A |
G |
7: 121,100,168 (GRCm39) |
D338G |
possibly damaging |
Het |
| Hsd3b6 |
T |
A |
3: 98,713,534 (GRCm39) |
Y255F |
probably benign |
Het |
| Hspa9 |
T |
C |
18: 35,076,329 (GRCm39) |
N328D |
possibly damaging |
Het |
| Hvcn1 |
T |
A |
5: 122,375,748 (GRCm39) |
I100N |
probably damaging |
Het |
| Ifi207 |
C |
T |
1: 173,556,494 (GRCm39) |
S748N |
possibly damaging |
Het |
| Katnip |
A |
T |
7: 125,464,434 (GRCm39) |
N1267I |
probably damaging |
Het |
| Kcnma1 |
G |
T |
14: 24,052,902 (GRCm39) |
T180K |
unknown |
Het |
| Kctd16 |
A |
G |
18: 40,391,826 (GRCm39) |
D138G |
probably damaging |
Het |
| Kifc3 |
A |
G |
8: 95,830,092 (GRCm39) |
Y605H |
probably benign |
Het |
| Kmt2d |
T |
A |
15: 98,743,376 (GRCm39) |
Q3928L |
unknown |
Het |
| Lamb2 |
C |
T |
9: 108,364,782 (GRCm39) |
R1179C |
probably damaging |
Het |
| Layn |
T |
A |
9: 50,968,670 (GRCm39) |
I358F |
possibly damaging |
Het |
| Lrig1 |
G |
A |
6: 94,603,452 (GRCm39) |
T232M |
probably damaging |
Het |
| Lrp1 |
T |
C |
10: 127,418,577 (GRCm39) |
T38A |
|
Het |
| Map3k14 |
A |
G |
11: 103,129,918 (GRCm39) |
V333A |
probably benign |
Het |
| Med13 |
T |
C |
11: 86,177,272 (GRCm39) |
D1608G |
possibly damaging |
Het |
| Mrps31 |
T |
G |
8: 22,911,429 (GRCm39) |
S224A |
probably benign |
Het |
| Msh6 |
G |
T |
17: 88,282,548 (GRCm39) |
|
|
Het |
| Ncapd3 |
A |
G |
9: 26,978,315 (GRCm39) |
D838G |
probably benign |
Het |
| Nlrp1a |
C |
A |
11: 70,987,919 (GRCm39) |
E1184* |
probably null |
Het |
| Npat |
T |
A |
9: 53,466,233 (GRCm39) |
|
probably null |
Het |
| Nup210 |
A |
T |
6: 91,050,227 (GRCm39) |
I414N |
probably benign |
Het |
| Or1e19 |
A |
T |
11: 73,316,419 (GRCm39) |
L130H |
probably damaging |
Het |
| Or52n2 |
A |
T |
7: 104,542,181 (GRCm39) |
V218E |
possibly damaging |
Het |
| Or5b122 |
T |
A |
19: 13,562,752 (GRCm39) |
I28N |
possibly damaging |
Het |
| Or5h19 |
T |
C |
16: 58,856,603 (GRCm39) |
T166A |
possibly damaging |
Het |
| Or6z5 |
T |
C |
7: 6,477,163 (GRCm39) |
L18P |
probably damaging |
Het |
| Or8b12c |
A |
T |
9: 37,715,257 (GRCm39) |
T17S |
possibly damaging |
Het |
| Or8h7 |
A |
C |
2: 86,721,217 (GRCm39) |
L101V |
probably benign |
Het |
| Otud7b |
G |
C |
3: 96,043,936 (GRCm39) |
|
probably null |
Het |
| Phf11d |
A |
C |
14: 59,596,942 (GRCm39) |
W86G |
probably benign |
Het |
| Pik3c2b |
T |
A |
1: 133,018,444 (GRCm39) |
S964T |
probably damaging |
Het |
| Pira1 |
T |
C |
7: 3,742,344 (GRCm39) |
Y61C |
probably damaging |
Het |
| Plod3 |
G |
A |
5: 137,023,901 (GRCm39) |
V687I |
probably benign |
Het |
| Poglut1 |
T |
G |
16: 38,358,284 (GRCm39) |
Y208S |
possibly damaging |
Het |
| Pou1f1 |
T |
A |
16: 65,330,749 (GRCm39) |
L253H |
probably damaging |
Het |
| Pou2f1 |
C |
T |
1: 165,738,955 (GRCm39) |
A166T |
unknown |
Het |
| Rhbdl3 |
C |
T |
11: 80,237,659 (GRCm39) |
S297L |
probably damaging |
Het |
| Rxra |
A |
T |
2: 27,631,866 (GRCm39) |
N179I |
probably damaging |
Het |
| Ryr2 |
C |
T |
13: 11,750,506 (GRCm39) |
E1922K |
probably damaging |
Het |
| Scube1 |
T |
C |
15: 83,499,211 (GRCm39) |
Y668C |
probably damaging |
Het |
| Sec16b |
A |
G |
1: 157,358,927 (GRCm39) |
Y120C |
probably damaging |
Het |
| Sec61b |
G |
T |
4: 47,483,047 (GRCm39) |
K92N |
probably damaging |
Het |
| Skic3 |
T |
A |
13: 76,296,866 (GRCm39) |
Y1074* |
probably null |
Het |
| Slc13a3 |
T |
C |
2: 165,275,984 (GRCm39) |
N254S |
possibly damaging |
Het |
| Slc17a7 |
T |
A |
7: 44,822,354 (GRCm39) |
Y397N |
probably benign |
Het |
| Slc25a3 |
A |
G |
10: 90,952,902 (GRCm39) |
V333A |
possibly damaging |
Het |
| Slc7a8 |
A |
T |
14: 54,964,283 (GRCm39) |
V390E |
probably damaging |
Het |
| Sorbs2 |
G |
A |
8: 46,212,233 (GRCm39) |
|
probably null |
Het |
| Srgap1 |
T |
C |
10: 121,621,650 (GRCm39) |
N948D |
probably benign |
Het |
| Tacc2 |
A |
T |
7: 130,225,066 (GRCm39) |
T584S |
probably benign |
Het |
| Tec |
A |
T |
5: 72,920,961 (GRCm39) |
D471E |
probably damaging |
Het |
| Tecpr2 |
C |
T |
12: 110,898,038 (GRCm39) |
A430V |
probably benign |
Het |
| Tmcc2 |
A |
T |
1: 132,288,759 (GRCm39) |
D309E |
probably damaging |
Het |
| Tmem82 |
G |
A |
4: 141,344,742 (GRCm39) |
A67V |
possibly damaging |
Het |
| Ttc23l |
T |
C |
15: 10,551,663 (GRCm39) |
Q21R |
probably damaging |
Het |
| Ubl3 |
A |
G |
5: 148,448,764 (GRCm39) |
F26L |
probably damaging |
Het |
| Upf2 |
A |
G |
2: 6,045,014 (GRCm39) |
E1088G |
unknown |
Het |
| Usp9y |
T |
A |
Y: 1,341,780 (GRCm39) |
I1362F |
probably benign |
Het |
| Wnk4 |
T |
A |
11: 101,159,318 (GRCm39) |
|
probably null |
Het |
| Wrn |
C |
G |
8: 33,738,994 (GRCm39) |
W1278S |
probably benign |
Het |
| Zfc3h1 |
T |
A |
10: 115,251,153 (GRCm39) |
V1248D |
probably damaging |
Het |
| Zfp12 |
T |
A |
5: 143,226,099 (GRCm39) |
V56D |
probably damaging |
Het |
|
| Other mutations in Dnah7c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00559:Dnah7c
|
APN |
1 |
46,846,449 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL02958:Dnah7c
|
APN |
1 |
46,696,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03035:Dnah7c
|
APN |
1 |
46,563,277 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL03161:Dnah7c
|
APN |
1 |
46,506,456 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL03178:Dnah7c
|
APN |
1 |
46,506,525 (GRCm39) |
missense |
probably benign |
|
|
IGL03052:Dnah7c
|
UTSW |
1 |
46,671,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0751:Dnah7c
|
UTSW |
1 |
46,505,065 (GRCm39) |
missense |
probably benign |
|
|
R1029:Dnah7c
|
UTSW |
1 |
46,651,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3104:Dnah7c
|
UTSW |
1 |
46,837,439 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3977:Dnah7c
|
UTSW |
1 |
46,668,071 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4003:Dnah7c
|
UTSW |
1 |
46,720,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4133:Dnah7c
|
UTSW |
1 |
46,705,150 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4303:Dnah7c
|
UTSW |
1 |
46,787,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4329:Dnah7c
|
UTSW |
1 |
46,688,441 (GRCm39) |
missense |
probably benign |
0.33 |
|
R4434:Dnah7c
|
UTSW |
1 |
46,705,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4457:Dnah7c
|
UTSW |
1 |
46,779,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4470:Dnah7c
|
UTSW |
1 |
46,787,795 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4507:Dnah7c
|
UTSW |
1 |
46,805,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4527:Dnah7c
|
UTSW |
1 |
46,572,091 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4571:Dnah7c
|
UTSW |
1 |
46,572,376 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4589:Dnah7c
|
UTSW |
1 |
46,553,743 (GRCm39) |
nonsense |
probably null |
|
|
R4731:Dnah7c
|
UTSW |
1 |
46,809,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4732:Dnah7c
|
UTSW |
1 |
46,809,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4733:Dnah7c
|
UTSW |
1 |
46,809,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4747:Dnah7c
|
UTSW |
1 |
46,572,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4845:Dnah7c
|
UTSW |
1 |
46,832,692 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4873:Dnah7c
|
UTSW |
1 |
46,728,085 (GRCm39) |
missense |
probably benign |
|
|
R4875:Dnah7c
|
UTSW |
1 |
46,728,085 (GRCm39) |
missense |
probably benign |
|
|
R4916:Dnah7c
|
UTSW |
1 |
46,634,168 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5241:Dnah7c
|
UTSW |
1 |
46,569,660 (GRCm39) |
missense |
probably benign |
|
|
R5279:Dnah7c
|
UTSW |
1 |
46,558,429 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5327:Dnah7c
|
UTSW |
1 |
46,704,728 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5546:Dnah7c
|
UTSW |
1 |
46,705,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5605:Dnah7c
|
UTSW |
1 |
46,837,395 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R5637:Dnah7c
|
UTSW |
1 |
46,799,521 (GRCm39) |
splice site |
probably null |
|
|
R5639:Dnah7c
|
UTSW |
1 |
46,778,828 (GRCm39) |
missense |
probably benign |
|
|
R5663:Dnah7c
|
UTSW |
1 |
46,574,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5718:Dnah7c
|
UTSW |
1 |
46,787,826 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R5759:Dnah7c
|
UTSW |
1 |
46,654,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5771:Dnah7c
|
UTSW |
1 |
46,678,825 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5784:Dnah7c
|
UTSW |
1 |
46,563,228 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5800:Dnah7c
|
UTSW |
1 |
46,686,175 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5933:Dnah7c
|
UTSW |
1 |
46,558,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5948:Dnah7c
|
UTSW |
1 |
46,711,657 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6034:Dnah7c
|
UTSW |
1 |
46,496,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6034:Dnah7c
|
UTSW |
1 |
46,496,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6487:Dnah7c
|
UTSW |
1 |
46,808,284 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6536:Dnah7c
|
UTSW |
1 |
46,697,450 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6614:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6614:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dnah7c
|
UTSW |
1 |
46,554,599 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6615:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6649:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6649:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6650:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6650:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6651:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6651:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6653:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6653:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6714:Dnah7c
|
UTSW |
1 |
46,779,966 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6729:Dnah7c
|
UTSW |
1 |
46,711,681 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6760:Dnah7c
|
UTSW |
1 |
46,688,500 (GRCm39) |
missense |
probably benign |
|
|
R6760:Dnah7c
|
UTSW |
1 |
46,688,511 (GRCm39) |
missense |
probably benign |
|
|
R6763:Dnah7c
|
UTSW |
1 |
46,668,050 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6866:Dnah7c
|
UTSW |
1 |
46,696,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6880:Dnah7c
|
UTSW |
1 |
46,566,831 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6988:Dnah7c
|
UTSW |
1 |
46,705,373 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6995:Dnah7c
|
UTSW |
1 |
46,494,973 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7007:Dnah7c
|
UTSW |
1 |
46,571,910 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7086:Dnah7c
|
UTSW |
1 |
46,789,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7128:Dnah7c
|
UTSW |
1 |
46,566,645 (GRCm39) |
missense |
probably benign |
|
|
R7131:Dnah7c
|
UTSW |
1 |
46,720,932 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7135:Dnah7c
|
UTSW |
1 |
46,572,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7171:Dnah7c
|
UTSW |
1 |
46,719,898 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7176:Dnah7c
|
UTSW |
1 |
46,469,969 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7221:Dnah7c
|
UTSW |
1 |
46,494,937 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7310:Dnah7c
|
UTSW |
1 |
46,636,127 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7319:Dnah7c
|
UTSW |
1 |
46,823,608 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7319:Dnah7c
|
UTSW |
1 |
46,819,935 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7452:Dnah7c
|
UTSW |
1 |
46,686,196 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7515:Dnah7c
|
UTSW |
1 |
46,496,450 (GRCm39) |
missense |
probably benign |
|
|
R7534:Dnah7c
|
UTSW |
1 |
46,809,227 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7542:Dnah7c
|
UTSW |
1 |
46,823,658 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7605:Dnah7c
|
UTSW |
1 |
46,671,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7643:Dnah7c
|
UTSW |
1 |
46,641,973 (GRCm39) |
missense |
probably benign |
|
|
R7770:Dnah7c
|
UTSW |
1 |
46,665,460 (GRCm39) |
splice site |
probably null |
|
|
R7884:Dnah7c
|
UTSW |
1 |
46,830,929 (GRCm39) |
missense |
probably benign |
0.23 |
|
R7899:Dnah7c
|
UTSW |
1 |
46,553,861 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8025:Dnah7c
|
UTSW |
1 |
46,496,456 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8057:Dnah7c
|
UTSW |
1 |
46,728,112 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8191:Dnah7c
|
UTSW |
1 |
46,646,618 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R8255:Dnah7c
|
UTSW |
1 |
46,698,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8428:Dnah7c
|
UTSW |
1 |
46,711,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8441:Dnah7c
|
UTSW |
1 |
46,572,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8485:Dnah7c
|
UTSW |
1 |
46,719,952 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8559:Dnah7c
|
UTSW |
1 |
46,764,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8752:Dnah7c
|
UTSW |
1 |
46,711,701 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8869:Dnah7c
|
UTSW |
1 |
46,671,504 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9058:Dnah7c
|
UTSW |
1 |
46,805,816 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9121:Dnah7c
|
UTSW |
1 |
46,816,896 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9121:Dnah7c
|
UTSW |
1 |
46,704,650 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9246:Dnah7c
|
UTSW |
1 |
46,571,934 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R9319:Dnah7c
|
UTSW |
1 |
46,521,168 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9388:Dnah7c
|
UTSW |
1 |
46,779,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,654,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,506,462 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,799,476 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
Z1176:Dnah7c
|
UTSW |
1 |
46,686,152 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1176:Dnah7c
|
UTSW |
1 |
46,678,825 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Dnah7c
|
UTSW |
1 |
46,693,263 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAGACTTGCTGCACACATGG -3'
(R):5'- AATCCGAAATGCGTCTCCAATGG -3'
Sequencing Primer
(F):5'- GCACACATGGCTGATTATTCAC -3'
(R):5'- GAAATGCGTCTCCAATGGGACTC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation