Incidental Mutation 'R7417:Sipa1l2'
| ID |
575391 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sipa1l2
|
| Ensembl Gene |
ENSMUSG00000001995 |
| Gene Name |
signal-induced proliferation-associated 1 like 2 |
| Synonyms |
|
| MMRRC Submission |
045495-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.324)
|
| Stock # |
R7417 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
8 |
| Chromosomal Location |
125418063-125569808 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 125482106 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 521
(D521G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000104405
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000108775]
[ENSMUST00000212168]
[ENSMUST00000212987]
|
| AlphaFold |
Q80TE4 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000108775
AA Change: D521G
PolyPhen 2
Score 0.925 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000104405
Gene: ENSMUSG00000001995
AA Change: D521G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
53 |
64 |
N/A |
INTRINSIC |
|
low complexity region
|
163 |
172 |
N/A |
INTRINSIC |
|
low complexity region
|
261 |
272 |
N/A |
INTRINSIC |
|
low complexity region
|
427 |
449 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
625 |
807 |
2.6e-67 |
PFAM |
|
PDZ
|
960 |
1026 |
6.47e-9 |
SMART |
|
low complexity region
|
1091 |
1103 |
N/A |
INTRINSIC |
|
low complexity region
|
1120 |
1138 |
N/A |
INTRINSIC |
|
low complexity region
|
1220 |
1238 |
N/A |
INTRINSIC |
|
low complexity region
|
1299 |
1312 |
N/A |
INTRINSIC |
|
low complexity region
|
1321 |
1329 |
N/A |
INTRINSIC |
|
low complexity region
|
1334 |
1355 |
N/A |
INTRINSIC |
|
low complexity region
|
1404 |
1418 |
N/A |
INTRINSIC |
|
Pfam:SPAR_C
|
1421 |
1666 |
2.5e-76 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000212168
AA Change: D521G
PolyPhen 2
Score 0.955 (Sensitivity: 0.79; Specificity: 0.95)
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000212987
AA Change: D521G
PolyPhen 2
Score 0.925 (Sensitivity: 0.81; Specificity: 0.94)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.2%
|
| Validation Efficiency |
100% (79/79) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the signal-induced proliferation-associated 1 like family. Members of this family contain a GTPase activating domain, a PDZ domain and a C-terminal coiled-coil domain with a leucine zipper. A similar protein in rat acts as a GTPases for the small GTPase Rap. [provided by RefSeq, Sep 2015]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A530064D06Rik |
G |
A |
17: 48,152,889 (GRCm38) |
T213I |
probably damaging |
Het |
| Akr1b7 |
G |
A |
6: 34,417,365 (GRCm38) |
|
probably null |
Het |
| Aldh6a1 |
T |
C |
12: 84,441,782 (GRCm38) |
Q110R |
probably benign |
Het |
| Alg11 |
A |
T |
8: 22,062,028 (GRCm38) |
T63S |
probably benign |
Het |
| Ankrd13b |
A |
G |
11: 77,476,194 (GRCm38) |
Y271H |
probably damaging |
Het |
| Ano8 |
T |
A |
8: 71,480,833 (GRCm38) |
D605V |
unknown |
Het |
| Best2 |
C |
T |
8: 85,009,666 (GRCm38) |
|
probably null |
Het |
| Brca1 |
A |
G |
11: 101,524,981 (GRCm38) |
S776P |
probably damaging |
Het |
| Capn7 |
T |
C |
14: 31,370,706 (GRCm38) |
Y737H |
probably damaging |
Het |
| Cblc |
A |
T |
7: 19,788,974 (GRCm38) |
S333T |
probably benign |
Het |
| Ccm2 |
T |
A |
11: 6,593,091 (GRCm38) |
M257K |
probably benign |
Het |
| Cd320 |
T |
A |
17: 33,847,556 (GRCm38) |
C103* |
probably null |
Het |
| Cd53 |
A |
G |
3: 106,768,919 (GRCm38) |
F44S |
probably benign |
Het |
| Col9a2 |
G |
A |
4: 121,054,292 (GRCm38) |
R610H |
not run |
Het |
| Cubn |
T |
C |
2: 13,426,967 (GRCm38) |
I1272V |
probably benign |
Het |
| Cyp2j7 |
C |
T |
4: 96,201,988 (GRCm38) |
|
probably null |
Het |
| Dmrt2 |
A |
T |
19: 25,678,598 (GRCm38) |
R520S |
probably benign |
Het |
| Dnai3 |
A |
T |
3: 146,093,080 (GRCm38) |
|
probably null |
Het |
| Drg2 |
A |
G |
11: 60,454,680 (GRCm38) |
M1V |
probably null |
Het |
| Ect2 |
A |
G |
3: 27,098,419 (GRCm38) |
S908P |
probably damaging |
Het |
| Eipr1 |
A |
G |
12: 28,866,955 (GRCm38) |
T341A |
probably benign |
Het |
| Ell3 |
A |
C |
2: 121,440,410 (GRCm38) |
I214R |
probably benign |
Het |
| Emsy |
A |
T |
7: 98,615,486 (GRCm38) |
L568Q |
probably damaging |
Het |
| Foxd4 |
T |
C |
19: 24,900,462 (GRCm38) |
T125A |
probably damaging |
Het |
| Fthl17b |
C |
T |
X: 8,962,808 (GRCm38) |
V8M |
possibly damaging |
Het |
| Fthl17b |
C |
T |
X: 8,962,804 (GRCm38) |
R9Q |
possibly damaging |
Het |
| Gcsam |
C |
A |
16: 45,619,877 (GRCm38) |
H94Q |
probably damaging |
Het |
| Ginm1 |
T |
A |
10: 7,774,080 (GRCm38) |
I150F |
probably damaging |
Het |
| H2bw2 |
G |
A |
X: 136,927,722 (GRCm38) |
R120K |
unknown |
Het |
| Hk2 |
G |
A |
6: 82,743,345 (GRCm38) |
A205V |
probably damaging |
Het |
| Il3ra |
A |
T |
14: 14,349,345 (GRCm38) |
H147L |
probably benign |
Het |
| Map3k6 |
T |
A |
4: 133,248,396 (GRCm38) |
S732T |
probably benign |
Het |
| Masp2 |
A |
G |
4: 148,605,721 (GRCm38) |
E229G |
probably benign |
Het |
| Mccc2 |
A |
G |
13: 99,971,777 (GRCm38) |
|
probably null |
Het |
| Mia3 |
A |
G |
1: 183,327,653 (GRCm38) |
V359A |
|
Het |
| Mob1a |
A |
T |
6: 83,332,510 (GRCm38) |
T80S |
probably benign |
Het |
| Msantd2 |
G |
A |
9: 37,523,294 (GRCm38) |
G478S |
probably damaging |
Het |
| Mtf1 |
A |
G |
4: 124,825,181 (GRCm38) |
E329G |
probably null |
Het |
| Myh9 |
T |
A |
15: 77,763,865 (GRCm38) |
K1804* |
probably null |
Het |
| Ndst3 |
A |
G |
3: 123,671,664 (GRCm38) |
W220R |
probably damaging |
Het |
| Nln |
A |
G |
13: 104,036,970 (GRCm38) |
L576P |
probably damaging |
Het |
| Nlrc4 |
A |
G |
17: 74,446,488 (GRCm38) |
M300T |
probably benign |
Het |
| Obscn |
G |
T |
11: 59,129,577 (GRCm38) |
D880E |
possibly damaging |
Het |
| Oprd1 |
T |
C |
4: 132,117,452 (GRCm38) |
T82A |
probably damaging |
Het |
| Or2n1d |
T |
A |
17: 38,335,292 (GRCm38) |
I45N |
probably damaging |
Het |
| Or4f60 |
A |
C |
2: 112,072,100 (GRCm38) |
V161G |
probably benign |
Het |
| Orc3 |
A |
G |
4: 34,595,136 (GRCm38) |
C278R |
probably damaging |
Het |
| Pde4d |
T |
A |
13: 109,632,788 (GRCm38) |
|
probably null |
Het |
| Pms1 |
T |
C |
1: 53,197,072 (GRCm38) |
E683G |
probably benign |
Het |
| Prdm2 |
A |
T |
4: 143,179,299 (GRCm38) |
Y73N |
probably damaging |
Het |
| Prkaa2 |
T |
C |
4: 105,075,543 (GRCm38) |
Q36R |
probably benign |
Het |
| Psg22 |
A |
G |
7: 18,722,966 (GRCm38) |
E258G |
probably damaging |
Het |
| Ptprf |
T |
C |
4: 118,212,172 (GRCm38) |
D1566G |
probably damaging |
Het |
| Rfwd3 |
T |
A |
8: 111,273,069 (GRCm38) |
Y759F |
probably benign |
Het |
| Ripor2 |
A |
G |
13: 24,696,550 (GRCm38) |
D411G |
probably damaging |
Het |
| Ryr2 |
A |
C |
13: 11,556,748 (GRCm38) |
|
probably null |
Het |
| Sdr42e1 |
T |
C |
8: 117,662,751 (GRCm38) |
T384A |
probably benign |
Het |
| Sec1 |
A |
T |
7: 45,684,725 (GRCm38) |
|
probably null |
Het |
| Sec16a |
A |
T |
2: 26,421,397 (GRCm38) |
F616I |
|
Het |
| Smc1b |
T |
A |
15: 85,097,542 (GRCm38) |
Q759L |
probably benign |
Het |
| Snph |
A |
T |
2: 151,600,343 (GRCm38) |
S57R |
probably damaging |
Het |
| Sqor |
A |
T |
2: 122,787,530 (GRCm38) |
T103S |
probably benign |
Het |
| Srbd1 |
A |
G |
17: 86,136,321 (GRCm38) |
V159A |
probably benign |
Het |
| Srsf2 |
A |
T |
11: 116,852,901 (GRCm38) |
V10E |
probably damaging |
Het |
| Swap70 |
T |
A |
7: 110,264,109 (GRCm38) |
|
probably null |
Het |
| Synm |
A |
C |
7: 67,733,206 (GRCm38) |
*675G |
probably null |
Het |
| Tek |
A |
G |
4: 94,811,345 (GRCm38) |
E320G |
probably benign |
Het |
| Tenm3 |
T |
C |
8: 48,236,183 (GRCm38) |
D2123G |
probably damaging |
Het |
| Tmod4 |
A |
G |
3: 95,125,863 (GRCm38) |
K56R |
possibly damaging |
Het |
| Top3b |
G |
A |
16: 16,877,850 (GRCm38) |
|
probably benign |
Het |
| Tssc4 |
G |
T |
7: 143,070,688 (GRCm38) |
E244D |
possibly damaging |
Het |
| Twnk |
G |
A |
19: 45,010,564 (GRCm38) |
|
probably null |
Het |
| Ube4a |
A |
C |
9: 44,956,713 (GRCm38) |
I45S |
probably benign |
Het |
| Unc79 |
A |
T |
12: 103,088,758 (GRCm38) |
M954L |
possibly damaging |
Het |
| Vcpip1 |
A |
T |
1: 9,746,315 (GRCm38) |
D614E |
probably benign |
Het |
| Vmn1r45 |
T |
A |
6: 89,933,053 (GRCm38) |
I312L |
probably benign |
Het |
| Vmn1r77 |
A |
G |
7: 12,041,684 (GRCm38) |
Y129C |
probably damaging |
Het |
| Zer1 |
A |
G |
2: 30,102,822 (GRCm38) |
L600P |
probably damaging |
Het |
| Zfp266 |
T |
C |
9: 20,500,936 (GRCm38) |
T114A |
probably benign |
Het |
| Zrsr2-ps1 |
T |
C |
11: 22,974,662 (GRCm38) |
|
probably null |
Het |
|
| Other mutations in Sipa1l2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00534:Sipa1l2
|
APN |
8 |
125,491,806 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00939:Sipa1l2
|
APN |
8 |
125,464,435 (GRCm38) |
splice site |
probably benign |
|
|
IGL00965:Sipa1l2
|
APN |
8 |
125,447,874 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL01321:Sipa1l2
|
APN |
8 |
125,491,518 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01450:Sipa1l2
|
APN |
8 |
125,422,577 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL01753:Sipa1l2
|
APN |
8 |
125,453,292 (GRCm38) |
splice site |
probably benign |
|
|
IGL01930:Sipa1l2
|
APN |
8 |
125,419,239 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02041:Sipa1l2
|
APN |
8 |
125,491,819 (GRCm38) |
missense |
probably benign |
0.03 |
|
IGL02215:Sipa1l2
|
APN |
8 |
125,447,837 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
IGL02272:Sipa1l2
|
APN |
8 |
125,492,011 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02370:Sipa1l2
|
APN |
8 |
125,480,269 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02538:Sipa1l2
|
APN |
8 |
125,451,977 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02633:Sipa1l2
|
APN |
8 |
125,447,768 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03394:Sipa1l2
|
APN |
8 |
125,491,659 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
Rebellious
|
UTSW |
8 |
125,468,339 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0144:Sipa1l2
|
UTSW |
8 |
125,449,876 (GRCm38) |
splice site |
probably null |
|
|
R0153:Sipa1l2
|
UTSW |
8 |
125,421,898 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0276:Sipa1l2
|
UTSW |
8 |
125,421,940 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0318:Sipa1l2
|
UTSW |
8 |
125,447,697 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R0373:Sipa1l2
|
UTSW |
8 |
125,464,410 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0427:Sipa1l2
|
UTSW |
8 |
125,480,332 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0634:Sipa1l2
|
UTSW |
8 |
125,422,624 (GRCm38) |
nonsense |
probably null |
|
|
R1377:Sipa1l2
|
UTSW |
8 |
125,491,977 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1404:Sipa1l2
|
UTSW |
8 |
125,449,973 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1404:Sipa1l2
|
UTSW |
8 |
125,449,973 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1435:Sipa1l2
|
UTSW |
8 |
125,468,725 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1523:Sipa1l2
|
UTSW |
8 |
125,447,613 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R1577:Sipa1l2
|
UTSW |
8 |
125,492,262 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1581:Sipa1l2
|
UTSW |
8 |
125,491,617 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1583:Sipa1l2
|
UTSW |
8 |
125,421,895 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R1719:Sipa1l2
|
UTSW |
8 |
125,444,535 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1730:Sipa1l2
|
UTSW |
8 |
125,480,141 (GRCm38) |
splice site |
probably null |
|
|
R1940:Sipa1l2
|
UTSW |
8 |
125,480,148 (GRCm38) |
splice site |
probably benign |
|
|
R2007:Sipa1l2
|
UTSW |
8 |
125,439,437 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2141:Sipa1l2
|
UTSW |
8 |
125,491,491 (GRCm38) |
missense |
probably benign |
0.07 |
|
R2203:Sipa1l2
|
UTSW |
8 |
125,491,627 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2764:Sipa1l2
|
UTSW |
8 |
125,492,374 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R3722:Sipa1l2
|
UTSW |
8 |
125,473,584 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3787:Sipa1l2
|
UTSW |
8 |
125,450,383 (GRCm38) |
missense |
possibly damaging |
0.52 |
|
R3787:Sipa1l2
|
UTSW |
8 |
125,423,205 (GRCm38) |
missense |
probably benign |
|
|
R4106:Sipa1l2
|
UTSW |
8 |
125,492,308 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4117:Sipa1l2
|
UTSW |
8 |
125,468,510 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4194:Sipa1l2
|
UTSW |
8 |
125,491,672 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4237:Sipa1l2
|
UTSW |
8 |
125,491,656 (GRCm38) |
missense |
probably benign |
0.44 |
|
R4240:Sipa1l2
|
UTSW |
8 |
125,491,656 (GRCm38) |
missense |
probably benign |
0.44 |
|
R4448:Sipa1l2
|
UTSW |
8 |
125,492,355 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4515:Sipa1l2
|
UTSW |
8 |
125,492,226 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4519:Sipa1l2
|
UTSW |
8 |
125,492,226 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4523:Sipa1l2
|
UTSW |
8 |
125,492,424 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4557:Sipa1l2
|
UTSW |
8 |
125,464,415 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4667:Sipa1l2
|
UTSW |
8 |
125,453,470 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R4687:Sipa1l2
|
UTSW |
8 |
125,491,245 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4854:Sipa1l2
|
UTSW |
8 |
125,473,601 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4890:Sipa1l2
|
UTSW |
8 |
125,491,867 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5065:Sipa1l2
|
UTSW |
8 |
125,491,585 (GRCm38) |
missense |
probably benign |
0.19 |
|
R5194:Sipa1l2
|
UTSW |
8 |
125,439,273 (GRCm38) |
missense |
possibly damaging |
0.48 |
|
R5266:Sipa1l2
|
UTSW |
8 |
125,492,126 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5475:Sipa1l2
|
UTSW |
8 |
125,491,595 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5718:Sipa1l2
|
UTSW |
8 |
125,491,248 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5910:Sipa1l2
|
UTSW |
8 |
125,491,684 (GRCm38) |
missense |
probably benign |
0.42 |
|
R5916:Sipa1l2
|
UTSW |
8 |
125,468,573 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5941:Sipa1l2
|
UTSW |
8 |
125,473,536 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6083:Sipa1l2
|
UTSW |
8 |
125,468,473 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R6185:Sipa1l2
|
UTSW |
8 |
125,468,253 (GRCm38) |
nonsense |
probably null |
|
|
R6235:Sipa1l2
|
UTSW |
8 |
125,474,871 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6274:Sipa1l2
|
UTSW |
8 |
125,469,872 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6299:Sipa1l2
|
UTSW |
8 |
125,453,464 (GRCm38) |
missense |
possibly damaging |
0.75 |
|
R6374:Sipa1l2
|
UTSW |
8 |
125,444,630 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6459:Sipa1l2
|
UTSW |
8 |
125,444,484 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6462:Sipa1l2
|
UTSW |
8 |
125,491,230 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6496:Sipa1l2
|
UTSW |
8 |
125,449,894 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6543:Sipa1l2
|
UTSW |
8 |
125,450,362 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R7154:Sipa1l2
|
UTSW |
8 |
125,468,339 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7192:Sipa1l2
|
UTSW |
8 |
125,422,609 (GRCm38) |
missense |
probably benign |
0.09 |
|
R7240:Sipa1l2
|
UTSW |
8 |
125,469,860 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7361:Sipa1l2
|
UTSW |
8 |
125,453,332 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7383:Sipa1l2
|
UTSW |
8 |
125,447,646 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7604:Sipa1l2
|
UTSW |
8 |
125,419,272 (GRCm38) |
missense |
probably benign |
0.45 |
|
R7658:Sipa1l2
|
UTSW |
8 |
125,492,290 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7743:Sipa1l2
|
UTSW |
8 |
125,464,233 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7781:Sipa1l2
|
UTSW |
8 |
125,491,827 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R7812:Sipa1l2
|
UTSW |
8 |
125,491,595 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7829:Sipa1l2
|
UTSW |
8 |
125,451,988 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7880:Sipa1l2
|
UTSW |
8 |
125,464,393 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7884:Sipa1l2
|
UTSW |
8 |
125,447,598 (GRCm38) |
missense |
probably benign |
|
|
R8057:Sipa1l2
|
UTSW |
8 |
125,468,530 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8082:Sipa1l2
|
UTSW |
8 |
125,491,809 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R8092:Sipa1l2
|
UTSW |
8 |
125,419,168 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8247:Sipa1l2
|
UTSW |
8 |
125,422,633 (GRCm38) |
missense |
probably benign |
0.29 |
|
R8252:Sipa1l2
|
UTSW |
8 |
125,468,671 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8386:Sipa1l2
|
UTSW |
8 |
125,492,093 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8466:Sipa1l2
|
UTSW |
8 |
125,492,246 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8697:Sipa1l2
|
UTSW |
8 |
125,482,116 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8725:Sipa1l2
|
UTSW |
8 |
125,450,386 (GRCm38) |
missense |
probably benign |
0.28 |
|
R8727:Sipa1l2
|
UTSW |
8 |
125,450,386 (GRCm38) |
missense |
probably benign |
0.28 |
|
R9048:Sipa1l2
|
UTSW |
8 |
125,447,726 (GRCm38) |
missense |
possibly damaging |
0.59 |
|
R9224:Sipa1l2
|
UTSW |
8 |
125,491,977 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9279:Sipa1l2
|
UTSW |
8 |
125,482,157 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9392:Sipa1l2
|
UTSW |
8 |
125,468,221 (GRCm38) |
missense |
probably benign |
|
|
R9574:Sipa1l2
|
UTSW |
8 |
125,442,714 (GRCm38) |
missense |
probably benign |
|
|
R9591:Sipa1l2
|
UTSW |
8 |
125,492,373 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9614:Sipa1l2
|
UTSW |
8 |
125,469,826 (GRCm38) |
missense |
probably null |
0.01 |
|
R9690:Sipa1l2
|
UTSW |
8 |
125,492,257 (GRCm38) |
missense |
probably benign |
|
|
X0027:Sipa1l2
|
UTSW |
8 |
125,492,136 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1177:Sipa1l2
|
UTSW |
8 |
125,447,556 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGGATGGGACCACATAACC -3'
(R):5'- AGATCCCAAGCCAGAGGATC -3'
Sequencing Primer
(F):5'- ACATAACCGCCTCTCAGTGTC -3'
(R):5'- AGAGGATCCCAGCCGTG -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation