Incidental Mutation 'R7419:Plxna1'
| ID |
575521 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxna1
|
| Ensembl Gene |
ENSMUSG00000030084 |
| Gene Name |
plexin A1 |
| Synonyms |
NOV, PlexA1, Plxn1, 2600013D04Rik |
| MMRRC Submission |
045497-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.888)
|
| Stock # |
R7419 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
89293295-89339595 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 89334584 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 15
(L15P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000063066
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000049845]
[ENSMUST00000163139]
|
| AlphaFold |
P70206 |
| PDB Structure |
The Plexin A1 intracellular region in complex with Rac1 [X-RAY DIFFRACTION]
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000049845
AA Change: L15P
|
| SMART Domains |
Protein: ENSMUSP00000063066
Gene: ENSMUSG00000030084
AA Change: L15P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
Sema
|
49 |
494 |
7.43e-126 |
SMART |
|
PSI
|
512 |
562 |
6.4e-11 |
SMART |
|
PSI
|
658 |
705 |
9.78e-7 |
SMART |
|
low complexity region
|
759 |
772 |
N/A |
INTRINSIC |
|
PSI
|
806 |
860 |
7.24e-10 |
SMART |
|
IPT
|
861 |
957 |
3.2e-26 |
SMART |
|
IPT
|
958 |
1043 |
1.59e-21 |
SMART |
|
IPT
|
1045 |
1145 |
6.86e-26 |
SMART |
|
IPT
|
1147 |
1242 |
1.64e-5 |
SMART |
|
transmembrane domain
|
1243 |
1265 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1316 |
1864 |
8.8e-263 |
PFAM |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000163139
AA Change: L15P
|
| SMART Domains |
Protein: ENSMUSP00000131840
Gene: ENSMUSG00000030084
AA Change: L15P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
Sema
|
49 |
494 |
7.43e-126 |
SMART |
|
PSI
|
512 |
562 |
6.4e-11 |
SMART |
|
PSI
|
658 |
705 |
9.78e-7 |
SMART |
|
low complexity region
|
759 |
772 |
N/A |
INTRINSIC |
|
PSI
|
806 |
860 |
7.24e-10 |
SMART |
|
IPT
|
861 |
957 |
3.2e-26 |
SMART |
|
IPT
|
958 |
1043 |
1.59e-21 |
SMART |
|
IPT
|
1045 |
1145 |
6.86e-26 |
SMART |
|
IPT
|
1147 |
1242 |
1.64e-5 |
SMART |
|
transmembrane domain
|
1243 |
1265 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1315 |
1864 |
2.5e-264 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
99% (93/94) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele exhibit bone cellularity abnormalities, altered dendritic cell physiology, abnormal proprioceptive and oligodendrocyte morphology, and increased lymphatic branching complexity and LEC numbers. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca13 |
T |
C |
11: 9,226,959 (GRCm39) |
S572P |
probably damaging |
Het |
| Abca13 |
T |
C |
11: 9,247,833 (GRCm39) |
Y2527H |
probably damaging |
Het |
| Abcc5 |
A |
G |
16: 20,241,173 (GRCm39) |
I4T |
possibly damaging |
Het |
| Adamts12 |
C |
T |
15: 11,317,365 (GRCm39) |
T1355I |
probably benign |
Het |
| Aloxe3 |
A |
G |
11: 69,018,353 (GRCm39) |
T117A |
probably benign |
Het |
| Asb15 |
A |
G |
6: 24,556,555 (GRCm39) |
I17V |
probably benign |
Het |
| Atf2 |
A |
G |
2: 73,672,777 (GRCm39) |
V194A |
probably benign |
Het |
| Capn7 |
T |
C |
14: 31,071,779 (GRCm39) |
V221A |
probably benign |
Het |
| Ccdc107 |
A |
T |
4: 43,493,512 (GRCm39) |
S28C |
probably benign |
Het |
| Cct4 |
C |
T |
11: 22,946,420 (GRCm39) |
T162I |
probably benign |
Het |
| Cdc40 |
A |
T |
10: 40,717,439 (GRCm39) |
H417Q |
probably damaging |
Het |
| Celf1 |
A |
G |
2: 90,833,588 (GRCm39) |
I115V |
probably benign |
Het |
| Ces3a |
A |
G |
8: 105,783,056 (GRCm39) |
Y395C |
probably damaging |
Het |
| Cfh |
C |
A |
1: 140,033,204 (GRCm39) |
C798F |
probably damaging |
Het |
| Clstn3 |
T |
C |
6: 124,435,088 (GRCm39) |
T313A |
probably benign |
Het |
| Crmp1 |
T |
A |
5: 37,436,229 (GRCm39) |
M329K |
probably benign |
Het |
| Csf2ra |
C |
T |
19: 61,215,491 (GRCm39) |
A76T |
possibly damaging |
Het |
| Cspg4 |
T |
A |
9: 56,795,727 (GRCm39) |
V1154E |
possibly damaging |
Het |
| Cyp2a4 |
A |
T |
7: 26,014,188 (GRCm39) |
N455I |
probably benign |
Het |
| Cyp4a32 |
T |
G |
4: 115,468,234 (GRCm39) |
M268R |
probably benign |
Het |
| Dcaf13 |
T |
A |
15: 38,993,615 (GRCm39) |
I236N |
probably damaging |
Het |
| Dennd2a |
A |
G |
6: 39,500,397 (GRCm39) |
I56T |
probably damaging |
Het |
| Eif2d |
T |
A |
1: 131,098,793 (GRCm39) |
S530R |
probably benign |
Het |
| Ep300 |
T |
A |
15: 81,532,715 (GRCm39) |
M1651K |
unknown |
Het |
| Epha3 |
G |
A |
16: 63,418,657 (GRCm39) |
T596I |
probably damaging |
Het |
| Fam171a2 |
C |
T |
11: 102,329,628 (GRCm39) |
C377Y |
possibly damaging |
Het |
| Fat4 |
T |
A |
3: 39,054,385 (GRCm39) |
N4142K |
probably damaging |
Het |
| Galnt5 |
C |
A |
2: 57,904,937 (GRCm39) |
S500Y |
probably damaging |
Het |
| Gas6 |
A |
G |
8: 13,521,456 (GRCm39) |
V431A |
probably benign |
Het |
| Gm7544 |
C |
T |
1: 82,933,502 (GRCm39) |
C56Y |
unknown |
Het |
| Golgb1 |
T |
A |
16: 36,733,281 (GRCm39) |
L884I |
possibly damaging |
Het |
| Gpatch2l |
T |
G |
12: 86,312,025 (GRCm39) |
|
probably null |
Het |
| Gpr33 |
T |
C |
12: 52,070,050 (GRCm39) |
T330A |
probably benign |
Het |
| H2bw2 |
G |
A |
X: 135,828,471 (GRCm39) |
R120K |
unknown |
Het |
| Ifi205 |
A |
G |
1: 173,855,874 (GRCm39) |
M52T |
possibly damaging |
Het |
| Ino80 |
A |
T |
2: 119,210,495 (GRCm39) |
D1346E |
probably benign |
Het |
| Ino80c |
T |
C |
18: 24,241,836 (GRCm39) |
K183R |
unknown |
Het |
| Itgal |
G |
T |
7: 126,906,047 (GRCm39) |
R379L |
probably benign |
Het |
| Itih3 |
T |
A |
14: 30,636,730 (GRCm39) |
T582S |
probably benign |
Het |
| Kcnb2 |
T |
C |
1: 15,781,251 (GRCm39) |
S708P |
possibly damaging |
Het |
| Kcnt1 |
A |
T |
2: 25,806,011 (GRCm39) |
Y1200F |
probably benign |
Het |
| L3mbtl4 |
G |
A |
17: 68,948,537 (GRCm39) |
D473N |
probably benign |
Het |
| Lama1 |
T |
G |
17: 68,024,169 (GRCm39) |
I89R |
|
Het |
| Lama2 |
A |
G |
10: 27,142,630 (GRCm39) |
I616T |
probably benign |
Het |
| Lipm |
A |
C |
19: 34,093,881 (GRCm39) |
D266A |
probably benign |
Het |
| Lrrc4c |
A |
T |
2: 97,460,106 (GRCm39) |
H244L |
probably benign |
Het |
| Lrrtm3 |
T |
C |
10: 63,923,925 (GRCm39) |
E414G |
probably damaging |
Het |
| Ltbp4 |
A |
G |
7: 27,029,192 (GRCm39) |
V231A |
unknown |
Het |
| Me3 |
G |
T |
7: 89,385,927 (GRCm39) |
R92L |
probably damaging |
Het |
| Mroh7 |
T |
G |
4: 106,541,115 (GRCm39) |
I1175L |
probably benign |
Het |
| Muc16 |
A |
G |
9: 18,553,258 (GRCm39) |
M4345T |
probably benign |
Het |
| Mug2 |
A |
G |
6: 122,017,529 (GRCm39) |
Y422C |
possibly damaging |
Het |
| N6amt1 |
T |
G |
16: 87,164,454 (GRCm39) |
S214A |
possibly damaging |
Het |
| Ogfrl1 |
G |
A |
1: 23,422,063 (GRCm39) |
Q24* |
probably null |
Het |
| Or12e14 |
A |
T |
2: 87,677,406 (GRCm39) |
T264S |
probably benign |
Het |
| Or1ad6 |
T |
A |
11: 50,860,152 (GRCm39) |
Y102* |
probably null |
Het |
| Or2ag2b |
T |
C |
7: 106,417,551 (GRCm39) |
L87P |
possibly damaging |
Het |
| Or4f14 |
G |
A |
2: 111,742,435 (GRCm39) |
P280L |
probably damaging |
Het |
| Or4k6 |
A |
C |
14: 50,475,448 (GRCm39) |
V298G |
possibly damaging |
Het |
| Or4x13 |
A |
G |
2: 90,231,803 (GRCm39) |
D266G |
probably damaging |
Het |
| Or6b6 |
A |
G |
7: 106,571,353 (GRCm39) |
M66T |
probably benign |
Het |
| Or7g23 |
A |
C |
9: 19,086,642 (GRCm39) |
M110R |
possibly damaging |
Het |
| Or8g23 |
T |
A |
9: 38,971,465 (GRCm39) |
I166L |
probably benign |
Het |
| Or8k3 |
C |
T |
2: 86,058,557 (GRCm39) |
G253R |
probably damaging |
Het |
| Oser1 |
A |
T |
2: 163,253,364 (GRCm39) |
D48E |
probably benign |
Het |
| Piwil4 |
G |
A |
9: 14,613,691 (GRCm39) |
P867L |
probably damaging |
Het |
| Pla2g6 |
C |
T |
15: 79,189,898 (GRCm39) |
|
probably null |
Het |
| Ppan |
C |
T |
9: 20,803,140 (GRCm39) |
T404I |
probably benign |
Het |
| Pros1 |
C |
A |
16: 62,748,433 (GRCm39) |
Y635* |
probably null |
Het |
| Rabep2 |
G |
A |
7: 126,043,342 (GRCm39) |
R414Q |
probably benign |
Het |
| Rbms3 |
T |
A |
9: 116,651,894 (GRCm39) |
E201V |
probably damaging |
Het |
| Robo4 |
A |
C |
9: 37,314,105 (GRCm39) |
I119L |
probably benign |
Het |
| S100b |
A |
T |
10: 76,095,820 (GRCm39) |
D66V |
probably damaging |
Het |
| Serpina1f |
A |
G |
12: 103,656,101 (GRCm39) |
S376P |
probably damaging |
Het |
| Slc24a4 |
T |
C |
12: 102,193,350 (GRCm39) |
|
probably null |
Het |
| Slc30a6 |
T |
C |
17: 74,730,424 (GRCm39) |
V438A |
probably benign |
Het |
| Sobp |
A |
G |
10: 42,897,804 (GRCm39) |
S594P |
probably benign |
Het |
| Tcstv1b |
A |
G |
13: 120,634,994 (GRCm39) |
E92G |
probably damaging |
Het |
| Tmem45b |
T |
C |
9: 31,339,334 (GRCm39) |
D213G |
probably benign |
Het |
| Topbp1 |
T |
A |
9: 103,200,543 (GRCm39) |
D525E |
probably benign |
Het |
| Trim30c |
G |
T |
7: 104,037,472 (GRCm39) |
L165I |
probably benign |
Het |
| Unc13b |
A |
T |
4: 43,174,023 (GRCm39) |
D1617V |
unknown |
Het |
| Ush1c |
A |
G |
7: 45,878,679 (GRCm39) |
L112P |
probably damaging |
Het |
| Vipr1 |
T |
A |
9: 121,490,539 (GRCm39) |
I195N |
probably damaging |
Het |
| Vmn2r38 |
A |
C |
7: 9,078,354 (GRCm39) |
V676G |
probably damaging |
Het |
| Vmn2r87 |
A |
T |
10: 130,307,992 (GRCm39) |
Y749N |
probably damaging |
Het |
| Vps13d |
A |
T |
4: 144,842,073 (GRCm39) |
S2615R |
|
Het |
| Whrn |
A |
G |
4: 63,334,330 (GRCm39) |
V828A |
possibly damaging |
Het |
| Zbp1 |
A |
G |
2: 173,050,958 (GRCm39) |
V304A |
probably benign |
Het |
| Zeb2 |
A |
T |
2: 44,886,359 (GRCm39) |
N899K |
probably benign |
Het |
| Zfp148 |
T |
C |
16: 33,317,511 (GRCm39) |
S728P |
possibly damaging |
Het |
| Zfp518a |
T |
A |
19: 40,902,207 (GRCm39) |
I712N |
possibly damaging |
Het |
| Zfp683 |
T |
C |
4: 133,786,211 (GRCm39) |
V446A |
probably benign |
Het |
| Zranb3 |
A |
T |
1: 127,891,588 (GRCm39) |
V796D |
possibly damaging |
Het |
|
| Other mutations in Plxna1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00427:Plxna1
|
APN |
6 |
89,297,980 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01358:Plxna1
|
APN |
6 |
89,299,732 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01475:Plxna1
|
APN |
6 |
89,331,870 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL01480:Plxna1
|
APN |
6 |
89,321,078 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
IGL01585:Plxna1
|
APN |
6 |
89,306,538 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01804:Plxna1
|
APN |
6 |
89,306,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01909:Plxna1
|
APN |
6 |
89,309,066 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01989:Plxna1
|
APN |
6 |
89,306,396 (GRCm39) |
nonsense |
probably null |
|
|
IGL02015:Plxna1
|
APN |
6 |
89,319,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02023:Plxna1
|
APN |
6 |
89,334,314 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL02668:Plxna1
|
APN |
6 |
89,334,251 (GRCm39) |
nonsense |
probably null |
|
|
IGL02703:Plxna1
|
APN |
6 |
89,333,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02954:Plxna1
|
APN |
6 |
89,301,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03212:Plxna1
|
APN |
6 |
89,308,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4544001:Plxna1
|
UTSW |
6 |
89,334,411 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0055:Plxna1
|
UTSW |
6 |
89,306,721 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0055:Plxna1
|
UTSW |
6 |
89,306,721 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0147:Plxna1
|
UTSW |
6 |
89,297,692 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0149:Plxna1
|
UTSW |
6 |
89,297,595 (GRCm39) |
missense |
probably null |
0.95 |
|
R0166:Plxna1
|
UTSW |
6 |
89,310,001 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0200:Plxna1
|
UTSW |
6 |
89,300,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0415:Plxna1
|
UTSW |
6 |
89,334,318 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0841:Plxna1
|
UTSW |
6 |
89,309,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1018:Plxna1
|
UTSW |
6 |
89,319,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1240:Plxna1
|
UTSW |
6 |
89,298,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1355:Plxna1
|
UTSW |
6 |
89,297,748 (GRCm39) |
unclassified |
probably benign |
|
|
R1700:Plxna1
|
UTSW |
6 |
89,333,990 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1776:Plxna1
|
UTSW |
6 |
89,312,446 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1957:Plxna1
|
UTSW |
6 |
89,308,273 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2314:Plxna1
|
UTSW |
6 |
89,301,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2968:Plxna1
|
UTSW |
6 |
89,319,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3118:Plxna1
|
UTSW |
6 |
89,333,958 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3522:Plxna1
|
UTSW |
6 |
89,314,335 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3619:Plxna1
|
UTSW |
6 |
89,334,435 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3766:Plxna1
|
UTSW |
6 |
89,311,757 (GRCm39) |
unclassified |
probably benign |
|
|
R3847:Plxna1
|
UTSW |
6 |
89,333,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3849:Plxna1
|
UTSW |
6 |
89,333,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3872:Plxna1
|
UTSW |
6 |
89,309,674 (GRCm39) |
nonsense |
probably null |
|
|
R4555:Plxna1
|
UTSW |
6 |
89,300,310 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4709:Plxna1
|
UTSW |
6 |
89,311,733 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4726:Plxna1
|
UTSW |
6 |
89,299,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4739:Plxna1
|
UTSW |
6 |
89,309,657 (GRCm39) |
splice site |
probably null |
|
|
R5053:Plxna1
|
UTSW |
6 |
89,299,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5221:Plxna1
|
UTSW |
6 |
89,297,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5449:Plxna1
|
UTSW |
6 |
89,300,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5480:Plxna1
|
UTSW |
6 |
89,301,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5575:Plxna1
|
UTSW |
6 |
89,301,523 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5743:Plxna1
|
UTSW |
6 |
89,333,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5744:Plxna1
|
UTSW |
6 |
89,311,664 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5754:Plxna1
|
UTSW |
6 |
89,310,087 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5868:Plxna1
|
UTSW |
6 |
89,299,704 (GRCm39) |
splice site |
probably benign |
|
|
R5988:Plxna1
|
UTSW |
6 |
89,334,522 (GRCm39) |
nonsense |
probably null |
|
|
R6190:Plxna1
|
UTSW |
6 |
89,333,586 (GRCm39) |
nonsense |
probably null |
|
|
R6425:Plxna1
|
UTSW |
6 |
89,311,647 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6561:Plxna1
|
UTSW |
6 |
89,333,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6623:Plxna1
|
UTSW |
6 |
89,299,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6638:Plxna1
|
UTSW |
6 |
89,301,382 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6701:Plxna1
|
UTSW |
6 |
89,296,430 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6825:Plxna1
|
UTSW |
6 |
89,297,597 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6911:Plxna1
|
UTSW |
6 |
89,297,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7073:Plxna1
|
UTSW |
6 |
89,334,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7177:Plxna1
|
UTSW |
6 |
89,300,311 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7235:Plxna1
|
UTSW |
6 |
89,317,573 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7511:Plxna1
|
UTSW |
6 |
89,318,889 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7543:Plxna1
|
UTSW |
6 |
89,299,837 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7665:Plxna1
|
UTSW |
6 |
89,301,520 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7678:Plxna1
|
UTSW |
6 |
89,308,882 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7748:Plxna1
|
UTSW |
6 |
89,314,335 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7748:Plxna1
|
UTSW |
6 |
89,314,334 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7877:Plxna1
|
UTSW |
6 |
89,300,241 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8025:Plxna1
|
UTSW |
6 |
89,308,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Plxna1
|
UTSW |
6 |
89,334,102 (GRCm39) |
missense |
probably benign |
0.20 |
|
R8277:Plxna1
|
UTSW |
6 |
89,334,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8782:Plxna1
|
UTSW |
6 |
89,300,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8867:Plxna1
|
UTSW |
6 |
89,310,079 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9245:Plxna1
|
UTSW |
6 |
89,314,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9253:Plxna1
|
UTSW |
6 |
89,334,522 (GRCm39) |
nonsense |
probably null |
|
|
R9269:Plxna1
|
UTSW |
6 |
89,306,541 (GRCm39) |
missense |
probably null |
1.00 |
|
R9273:Plxna1
|
UTSW |
6 |
89,296,364 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9281:Plxna1
|
UTSW |
6 |
89,300,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9368:Plxna1
|
UTSW |
6 |
89,314,138 (GRCm39) |
missense |
probably benign |
|
|
R9440:Plxna1
|
UTSW |
6 |
89,318,912 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9526:Plxna1
|
UTSW |
6 |
89,319,633 (GRCm39) |
missense |
probably benign |
|
|
R9601:Plxna1
|
UTSW |
6 |
89,308,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9714:Plxna1
|
UTSW |
6 |
89,296,440 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9782:Plxna1
|
UTSW |
6 |
89,333,817 (GRCm39) |
missense |
probably benign |
0.01 |
|
S24628:Plxna1
|
UTSW |
6 |
89,334,318 (GRCm39) |
missense |
probably benign |
0.12 |
|
V8831:Plxna1
|
UTSW |
6 |
89,334,119 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Plxna1
|
UTSW |
6 |
89,298,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCTTGTAAATACGGTTCACAGC -3'
(R):5'- TTGGAGGCATCTGCATAGC -3'
Sequencing Primer
(F):5'- GGTTCACAGCGCCAACATATAC -3'
(R):5'- ATCTGCATAGCACGGCG -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation