Incidental Mutation 'R7422:Tanc1'
| ID |
575704 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tanc1
|
| Ensembl Gene |
ENSMUSG00000035168 |
| Gene Name |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 |
| Synonyms |
1200003E16Rik |
| MMRRC Submission |
045500-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7422 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
59442386-59676493 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 59636688 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Threonine
at position 857
(M857T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000123345
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037526]
[ENSMUST00000112568]
[ENSMUST00000139863]
|
| AlphaFold |
Q0VGY8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000037526
AA Change: M857T
PolyPhen 2
Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000036003
Gene: ENSMUSG00000035168
AA Change: M857T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
439 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
475 |
N/A |
INTRINSIC |
|
ANK
|
893 |
925 |
1.06e3 |
SMART |
|
ANK
|
929 |
960 |
2.43e3 |
SMART |
|
ANK
|
964 |
993 |
1.12e-3 |
SMART |
|
Blast:ANK
|
997 |
1028 |
7e-12 |
BLAST |
|
ANK
|
1037 |
1066 |
1.78e3 |
SMART |
|
ANK
|
1075 |
1104 |
2.34e-1 |
SMART |
|
ANK
|
1108 |
1137 |
3.71e-4 |
SMART |
|
ANK
|
1141 |
1170 |
1.51e-4 |
SMART |
|
ANK
|
1174 |
1203 |
4.89e-4 |
SMART |
|
ANK
|
1207 |
1236 |
3.01e-4 |
SMART |
|
ANK
|
1240 |
1269 |
1.99e2 |
SMART |
|
TPR
|
1286 |
1319 |
7.49e1 |
SMART |
|
TPR
|
1333 |
1366 |
2.35e-1 |
SMART |
|
TPR
|
1367 |
1400 |
6.29e-2 |
SMART |
|
low complexity region
|
1416 |
1432 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1483 |
N/A |
INTRINSIC |
|
low complexity region
|
1656 |
1686 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112568
AA Change: M850T
PolyPhen 2
Score 0.011 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000108187
Gene: ENSMUSG00000035168
AA Change: M850T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
444 |
N/A |
INTRINSIC |
|
low complexity region
|
448 |
468 |
N/A |
INTRINSIC |
|
ANK
|
886 |
918 |
1.06e3 |
SMART |
|
ANK
|
922 |
953 |
2.43e3 |
SMART |
|
ANK
|
957 |
986 |
1.12e-3 |
SMART |
|
Blast:ANK
|
990 |
1021 |
7e-12 |
BLAST |
|
ANK
|
1030 |
1059 |
1.78e3 |
SMART |
|
ANK
|
1068 |
1097 |
2.34e-1 |
SMART |
|
ANK
|
1101 |
1130 |
3.71e-4 |
SMART |
|
ANK
|
1134 |
1163 |
1.51e-4 |
SMART |
|
ANK
|
1167 |
1196 |
4.89e-4 |
SMART |
|
ANK
|
1200 |
1229 |
3.01e-4 |
SMART |
|
ANK
|
1233 |
1262 |
1.99e2 |
SMART |
|
TPR
|
1279 |
1312 |
7.49e1 |
SMART |
|
TPR
|
1326 |
1359 |
2.35e-1 |
SMART |
|
TPR
|
1360 |
1393 |
6.29e-2 |
SMART |
|
low complexity region
|
1409 |
1425 |
N/A |
INTRINSIC |
|
low complexity region
|
1447 |
1476 |
N/A |
INTRINSIC |
|
low complexity region
|
1649 |
1679 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000139863
AA Change: M857T
PolyPhen 2
Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000123345
Gene: ENSMUSG00000035168
AA Change: M857T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
60 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
171 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
439 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
475 |
N/A |
INTRINSIC |
|
ANK
|
893 |
925 |
1.06e3 |
SMART |
|
ANK
|
929 |
960 |
2.43e3 |
SMART |
|
ANK
|
964 |
993 |
1.12e-3 |
SMART |
|
Blast:ANK
|
997 |
1028 |
7e-12 |
BLAST |
|
ANK
|
1037 |
1066 |
1.78e3 |
SMART |
|
ANK
|
1075 |
1104 |
2.34e-1 |
SMART |
|
ANK
|
1108 |
1137 |
3.71e-4 |
SMART |
|
ANK
|
1141 |
1170 |
1.51e-4 |
SMART |
|
ANK
|
1174 |
1203 |
4.89e-4 |
SMART |
|
ANK
|
1207 |
1236 |
3.01e-4 |
SMART |
|
ANK
|
1240 |
1269 |
1.99e2 |
SMART |
|
TPR
|
1286 |
1319 |
7.49e1 |
SMART |
|
TPR
|
1333 |
1366 |
2.35e-1 |
SMART |
|
TPR
|
1367 |
1400 |
6.29e-2 |
SMART |
|
low complexity region
|
1416 |
1432 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1483 |
N/A |
INTRINSIC |
|
low complexity region
|
1656 |
1686 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.1%
- 20x: 96.9%
|
| Validation Efficiency |
97% (98/101) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap vector exhibit decreased spine density in the CA3 region and impaired spatial memory. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 99 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810021J22Rik |
T |
A |
11: 58,771,885 (GRCm39) |
C456S |
probably damaging |
Het |
| 4930524J08Rik |
T |
C |
5: 100,127,068 (GRCm39) |
|
probably benign |
Het |
| Adam28 |
T |
G |
14: 68,864,326 (GRCm39) |
R492S |
probably damaging |
Het |
| Adarb2 |
G |
A |
13: 8,807,313 (GRCm39) |
A705T |
possibly damaging |
Het |
| Adprhl1 |
T |
C |
8: 13,272,873 (GRCm39) |
D1295G |
probably benign |
Het |
| Aldh3b3 |
A |
G |
19: 4,016,476 (GRCm39) |
I365V |
probably benign |
Het |
| Aldh8a1 |
T |
C |
10: 21,264,996 (GRCm39) |
F208L |
possibly damaging |
Het |
| Ap3b1 |
G |
A |
13: 94,664,673 (GRCm39) |
V871I |
unknown |
Het |
| Apol7e |
A |
T |
15: 77,598,552 (GRCm39) |
R6* |
probably null |
Het |
| Arfgap3 |
T |
C |
15: 83,191,150 (GRCm39) |
E456G |
probably damaging |
Het |
| Arhgef1 |
T |
C |
7: 24,615,461 (GRCm39) |
L285P |
probably benign |
Het |
| Arhgef7 |
T |
A |
8: 11,850,861 (GRCm39) |
C315S |
probably benign |
Het |
| Atp9a |
A |
T |
2: 168,490,513 (GRCm39) |
L829Q |
probably damaging |
Het |
| Babam2 |
T |
A |
5: 31,888,393 (GRCm39) |
|
probably null |
Het |
| Bptf |
C |
T |
11: 106,951,384 (GRCm39) |
R2185H |
probably damaging |
Het |
| Brd9 |
A |
C |
13: 74,102,697 (GRCm39) |
M473L |
probably benign |
Het |
| C7 |
T |
C |
15: 5,041,538 (GRCm39) |
H456R |
probably benign |
Het |
| Cabp7 |
C |
A |
11: 4,688,856 (GRCm39) |
A205S |
probably damaging |
Het |
| Catsperb |
A |
G |
12: 101,554,293 (GRCm39) |
I662M |
probably damaging |
Het |
| Ccl21a |
T |
C |
4: 42,773,906 (GRCm39) |
M5V |
probably benign |
Het |
| Cdyl |
G |
T |
13: 36,042,177 (GRCm39) |
R405L |
possibly damaging |
Het |
| Cep89 |
T |
C |
7: 35,127,672 (GRCm39) |
L538P |
probably damaging |
Het |
| Cercam |
A |
G |
2: 29,762,892 (GRCm39) |
M209V |
possibly damaging |
Het |
| Chfr |
T |
A |
5: 110,310,571 (GRCm39) |
|
probably null |
Het |
| Cntnap5c |
T |
A |
17: 58,717,226 (GRCm39) |
Y1269* |
probably null |
Het |
| Col6a2 |
G |
T |
10: 76,439,170 (GRCm39) |
C833* |
probably null |
Het |
| Cpeb3 |
T |
A |
19: 37,151,900 (GRCm39) |
I159F |
probably benign |
Het |
| Cplx2 |
G |
A |
13: 54,526,663 (GRCm39) |
E24K |
possibly damaging |
Het |
| Ctsb |
A |
G |
14: 63,379,752 (GRCm39) |
T332A |
probably benign |
Het |
| Cyp2j12 |
T |
A |
4: 96,029,222 (GRCm39) |
T20S |
probably benign |
Het |
| Dcst2 |
T |
A |
3: 89,273,993 (GRCm39) |
H181Q |
probably damaging |
Het |
| Dnm1l |
T |
C |
16: 16,136,338 (GRCm39) |
I411V |
probably benign |
Het |
| Dock5 |
T |
A |
14: 68,046,479 (GRCm39) |
I768F |
probably benign |
Het |
| Ecel1 |
A |
G |
1: 87,077,334 (GRCm39) |
Y625H |
probably damaging |
Het |
| Efl1 |
T |
G |
7: 82,330,587 (GRCm39) |
S253R |
probably damaging |
Het |
| Elmod1 |
T |
A |
9: 53,820,127 (GRCm39) |
D287V |
probably damaging |
Het |
| Fam171a2 |
T |
C |
11: 102,329,491 (GRCm39) |
S423G |
probably benign |
Het |
| Fbxo8 |
A |
T |
8: 57,022,317 (GRCm39) |
|
probably null |
Het |
| Flnc |
G |
T |
6: 29,455,470 (GRCm39) |
G2040W |
probably damaging |
Het |
| Fras1 |
C |
T |
5: 96,821,458 (GRCm39) |
A1405V |
probably benign |
Het |
| Frem3 |
A |
C |
8: 81,342,392 (GRCm39) |
I1562L |
probably benign |
Het |
| Fxr1 |
C |
T |
3: 34,103,369 (GRCm39) |
A233V |
probably damaging |
Het |
| H1f9 |
A |
G |
11: 94,859,184 (GRCm39) |
R160G |
possibly damaging |
Het |
| Helb |
A |
G |
10: 119,944,799 (GRCm39) |
F246L |
probably damaging |
Het |
| Hoxb6 |
G |
T |
11: 96,183,510 (GRCm39) |
|
probably benign |
Het |
| Hspa2 |
A |
G |
12: 76,452,884 (GRCm39) |
E526G |
probably damaging |
Het |
| Hyal5 |
A |
T |
6: 24,875,983 (GRCm39) |
|
probably benign |
Het |
| Ints6 |
A |
T |
14: 62,942,224 (GRCm39) |
V503E |
probably benign |
Het |
| Ints9 |
C |
T |
14: 65,269,747 (GRCm39) |
T479I |
possibly damaging |
Het |
| Jag1 |
C |
T |
2: 136,926,975 (GRCm39) |
R928H |
probably benign |
Het |
| Lman2 |
A |
T |
13: 55,499,338 (GRCm39) |
I179N |
probably damaging |
Het |
| Lta |
T |
C |
17: 35,422,805 (GRCm39) |
S173G |
probably benign |
Het |
| Mki67 |
G |
A |
7: 135,300,099 (GRCm39) |
P1645L |
probably damaging |
Het |
| Mrc2 |
A |
T |
11: 105,183,609 (GRCm39) |
|
probably benign |
Het |
| Muc4 |
T |
A |
16: 32,754,689 (GRCm38) |
M1521K |
probably benign |
Het |
| Mucl3 |
T |
A |
17: 35,949,312 (GRCm39) |
T96S |
probably benign |
Het |
| Mylk3 |
T |
G |
8: 86,081,873 (GRCm39) |
D438A |
probably benign |
Het |
| Myo7a |
T |
A |
7: 97,700,833 (GRCm39) |
|
probably null |
Het |
| Nsmce4a |
G |
T |
7: 130,135,547 (GRCm39) |
Q342K |
probably benign |
Het |
| Or10ac1 |
A |
G |
6: 42,515,053 (GRCm39) |
I301T |
possibly damaging |
Het |
| Or4c124 |
T |
A |
2: 89,156,423 (GRCm39) |
I34F |
probably benign |
Het |
| Or5p60 |
A |
G |
7: 107,724,068 (GRCm39) |
L134P |
probably damaging |
Het |
| Or6c65 |
A |
T |
10: 129,604,136 (GRCm39) |
Y257F |
possibly damaging |
Het |
| Osbpl6 |
T |
A |
2: 76,423,730 (GRCm39) |
F864L |
probably damaging |
Het |
| Pla2g4a |
A |
G |
1: 149,808,438 (GRCm39) |
S2P |
probably benign |
Het |
| Plce1 |
T |
C |
19: 38,640,329 (GRCm39) |
L525P |
probably damaging |
Het |
| Por |
A |
T |
5: 135,763,773 (GRCm39) |
M667L |
probably benign |
Het |
| Psma4 |
T |
C |
9: 54,862,166 (GRCm39) |
Y97H |
probably benign |
Het |
| Qtrt1 |
A |
T |
9: 21,323,753 (GRCm39) |
H126L |
probably benign |
Het |
| Rab3a |
A |
T |
8: 71,209,170 (GRCm39) |
Y102F |
possibly damaging |
Het |
| Rnf212 |
T |
A |
5: 108,879,555 (GRCm39) |
H87L |
probably benign |
Het |
| Rnf216 |
A |
G |
5: 143,076,591 (GRCm39) |
S98P |
probably benign |
Het |
| Ryr1 |
G |
T |
7: 28,785,295 (GRCm39) |
R1806S |
probably benign |
Het |
| Scgb1b3 |
A |
T |
7: 31,075,262 (GRCm39) |
L37F |
probably benign |
Het |
| Sds |
T |
C |
5: 120,617,254 (GRCm39) |
S37P |
probably damaging |
Het |
| Senp6 |
A |
G |
9: 80,021,159 (GRCm39) |
R280G |
probably damaging |
Het |
| She |
T |
A |
3: 89,761,864 (GRCm39) |
I441K |
possibly damaging |
Het |
| Slc6a20b |
A |
G |
9: 123,436,682 (GRCm39) |
S244P |
possibly damaging |
Het |
| Slc9a3 |
A |
T |
13: 74,299,004 (GRCm39) |
Y141F |
probably damaging |
Het |
| Slco6c1 |
A |
T |
1: 97,009,207 (GRCm39) |
H426Q |
probably benign |
Het |
| Smc2 |
C |
A |
4: 52,440,301 (GRCm39) |
Q16K |
probably benign |
Het |
| Sphkap |
A |
C |
1: 83,241,547 (GRCm39) |
V1535G |
probably benign |
Het |
| Stard9 |
C |
A |
2: 120,532,633 (GRCm39) |
N2963K |
probably benign |
Het |
| Sycp2 |
C |
T |
2: 178,035,944 (GRCm39) |
A248T |
probably damaging |
Het |
| Taar8a |
T |
C |
10: 23,952,762 (GRCm39) |
L122P |
probably damaging |
Het |
| Tab1 |
T |
A |
15: 80,044,445 (GRCm39) |
V491E |
probably benign |
Het |
| Tcirg1 |
C |
A |
19: 3,949,008 (GRCm39) |
R427L |
possibly damaging |
Het |
| Tmem109 |
A |
C |
19: 10,849,124 (GRCm39) |
*244G |
probably null |
Het |
| Tox2 |
A |
G |
2: 163,163,435 (GRCm39) |
Y136C |
|
Het |
| Tubb1 |
T |
C |
2: 174,298,825 (GRCm39) |
V169A |
possibly damaging |
Het |
| Ubr3 |
T |
C |
2: 69,783,886 (GRCm39) |
|
probably null |
Het |
| Vmn1r225 |
T |
A |
17: 20,723,059 (GRCm39) |
F167I |
probably benign |
Het |
| Vmn2r65 |
A |
C |
7: 84,595,569 (GRCm39) |
W372G |
probably damaging |
Het |
| Vps13a |
A |
T |
19: 16,727,537 (GRCm39) |
D188E |
probably damaging |
Het |
| Vsnl1 |
G |
T |
12: 11,376,439 (GRCm39) |
Q149K |
probably benign |
Het |
| Wdr35 |
A |
G |
12: 9,054,105 (GRCm39) |
N466S |
probably benign |
Het |
| Ywhae |
T |
A |
11: 75,650,169 (GRCm39) |
S210R |
probably damaging |
Het |
| Zfp28 |
T |
A |
7: 6,397,748 (GRCm39) |
S728T |
probably damaging |
Het |
| Zfpm1 |
A |
G |
8: 123,063,698 (GRCm39) |
D919G |
unknown |
Het |
|
| Other mutations in Tanc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00340:Tanc1
|
APN |
2 |
59,621,185 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL00484:Tanc1
|
APN |
2 |
59,623,520 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00688:Tanc1
|
APN |
2 |
59,645,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00765:Tanc1
|
APN |
2 |
59,636,645 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01576:Tanc1
|
APN |
2 |
59,628,079 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01590:Tanc1
|
APN |
2 |
59,615,817 (GRCm39) |
missense |
probably benign |
|
|
IGL02016:Tanc1
|
APN |
2 |
59,673,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02373:Tanc1
|
APN |
2 |
59,626,372 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02539:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02540:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02541:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02543:Tanc1
|
APN |
2 |
59,663,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02559:Tanc1
|
APN |
2 |
59,554,998 (GRCm39) |
splice site |
probably benign |
|
|
IGL02626:Tanc1
|
APN |
2 |
59,630,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02669:Tanc1
|
APN |
2 |
59,630,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02902:Tanc1
|
APN |
2 |
59,623,431 (GRCm39) |
splice site |
probably benign |
|
|
Oreja
|
UTSW |
2 |
59,622,148 (GRCm39) |
synonymous |
silent |
|
|
R0178:Tanc1
|
UTSW |
2 |
59,665,791 (GRCm39) |
nonsense |
probably null |
|
|
R0347:Tanc1
|
UTSW |
2 |
59,673,335 (GRCm39) |
missense |
probably benign |
|
|
R0570:Tanc1
|
UTSW |
2 |
59,626,382 (GRCm39) |
splice site |
probably benign |
|
|
R0660:Tanc1
|
UTSW |
2 |
59,674,228 (GRCm39) |
nonsense |
probably null |
|
|
R0664:Tanc1
|
UTSW |
2 |
59,674,228 (GRCm39) |
nonsense |
probably null |
|
|
R0898:Tanc1
|
UTSW |
2 |
59,621,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1333:Tanc1
|
UTSW |
2 |
59,673,835 (GRCm39) |
missense |
probably benign |
|
|
R1575:Tanc1
|
UTSW |
2 |
59,621,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1608:Tanc1
|
UTSW |
2 |
59,628,038 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1616:Tanc1
|
UTSW |
2 |
59,615,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1703:Tanc1
|
UTSW |
2 |
59,673,365 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1727:Tanc1
|
UTSW |
2 |
59,621,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1809:Tanc1
|
UTSW |
2 |
59,630,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1812:Tanc1
|
UTSW |
2 |
59,622,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1925:Tanc1
|
UTSW |
2 |
59,555,095 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R1951:Tanc1
|
UTSW |
2 |
59,622,156 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2174:Tanc1
|
UTSW |
2 |
59,674,177 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2228:Tanc1
|
UTSW |
2 |
59,555,068 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2267:Tanc1
|
UTSW |
2 |
59,667,563 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4191:Tanc1
|
UTSW |
2 |
59,669,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4476:Tanc1
|
UTSW |
2 |
59,672,340 (GRCm39) |
splice site |
probably null |
|
|
R4632:Tanc1
|
UTSW |
2 |
59,626,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4825:Tanc1
|
UTSW |
2 |
59,529,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4982:Tanc1
|
UTSW |
2 |
59,630,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5338:Tanc1
|
UTSW |
2 |
59,626,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5657:Tanc1
|
UTSW |
2 |
59,665,051 (GRCm39) |
splice site |
probably null |
|
|
R5672:Tanc1
|
UTSW |
2 |
59,602,697 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5703:Tanc1
|
UTSW |
2 |
59,626,341 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5707:Tanc1
|
UTSW |
2 |
59,588,874 (GRCm39) |
missense |
probably benign |
|
|
R5778:Tanc1
|
UTSW |
2 |
59,529,691 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5795:Tanc1
|
UTSW |
2 |
59,637,926 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R5831:Tanc1
|
UTSW |
2 |
59,615,685 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5849:Tanc1
|
UTSW |
2 |
59,630,248 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5912:Tanc1
|
UTSW |
2 |
59,622,030 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5944:Tanc1
|
UTSW |
2 |
59,667,564 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6057:Tanc1
|
UTSW |
2 |
59,647,837 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6142:Tanc1
|
UTSW |
2 |
59,663,566 (GRCm39) |
nonsense |
probably null |
|
|
R6179:Tanc1
|
UTSW |
2 |
59,673,320 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6185:Tanc1
|
UTSW |
2 |
59,621,929 (GRCm39) |
splice site |
probably null |
|
|
R6192:Tanc1
|
UTSW |
2 |
59,669,305 (GRCm39) |
splice site |
probably null |
|
|
R6196:Tanc1
|
UTSW |
2 |
59,674,366 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6197:Tanc1
|
UTSW |
2 |
59,674,366 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6230:Tanc1
|
UTSW |
2 |
59,672,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6275:Tanc1
|
UTSW |
2 |
59,673,854 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6415:Tanc1
|
UTSW |
2 |
59,667,458 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6480:Tanc1
|
UTSW |
2 |
59,637,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6578:Tanc1
|
UTSW |
2 |
59,626,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6786:Tanc1
|
UTSW |
2 |
59,622,150 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7006:Tanc1
|
UTSW |
2 |
59,626,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7133:Tanc1
|
UTSW |
2 |
59,627,953 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7381:Tanc1
|
UTSW |
2 |
59,615,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8392:Tanc1
|
UTSW |
2 |
59,636,651 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8692:Tanc1
|
UTSW |
2 |
59,673,989 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8730:Tanc1
|
UTSW |
2 |
59,601,590 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8731:Tanc1
|
UTSW |
2 |
59,673,596 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8813:Tanc1
|
UTSW |
2 |
59,630,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8815:Tanc1
|
UTSW |
2 |
59,621,185 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8933:Tanc1
|
UTSW |
2 |
59,615,800 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9015:Tanc1
|
UTSW |
2 |
59,622,224 (GRCm39) |
missense |
probably benign |
|
|
R9042:Tanc1
|
UTSW |
2 |
59,673,766 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9154:Tanc1
|
UTSW |
2 |
59,630,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9269:Tanc1
|
UTSW |
2 |
59,630,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9283:Tanc1
|
UTSW |
2 |
59,630,174 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9380:Tanc1
|
UTSW |
2 |
59,665,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9422:Tanc1
|
UTSW |
2 |
59,637,933 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9428:Tanc1
|
UTSW |
2 |
59,601,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9694:Tanc1
|
UTSW |
2 |
59,626,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF028:Tanc1
|
UTSW |
2 |
59,673,613 (GRCm39) |
small deletion |
probably benign |
|
|
RF049:Tanc1
|
UTSW |
2 |
59,673,613 (GRCm39) |
small deletion |
probably benign |
|
|
X0063:Tanc1
|
UTSW |
2 |
59,674,324 (GRCm39) |
nonsense |
probably null |
|
|
X0064:Tanc1
|
UTSW |
2 |
59,674,456 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tanc1
|
UTSW |
2 |
59,602,873 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Tanc1
|
UTSW |
2 |
59,622,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Tanc1
|
UTSW |
2 |
59,621,231 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CTCCCACAGATGACAGTTCAGG -3'
(R):5'- TCACGCATCACTTTGAGACAAGG -3'
Sequencing Primer
(F):5'- GGGCACAGTGGGATGTCCTTATC -3'
(R):5'- GGCGATATGAAACTATATGCCCATG -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation