Incidental Mutation 'R7422:Sycp2'
| ID |
575713 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sycp2
|
| Ensembl Gene |
ENSMUSG00000060445 |
| Gene Name |
synaptonemal complex protein 2 |
| Synonyms |
3830402K23Rik, 4930518F03Rik |
| MMRRC Submission |
045500-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7422 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
177987086-178049478 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 178035944 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Threonine
at position 248
(A248T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000079909
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000081134]
[ENSMUST00000138175]
|
| AlphaFold |
Q9CUU3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000081134
AA Change: A248T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000079909
Gene: ENSMUSG00000060445
AA Change: A248T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
945 |
960 |
N/A |
INTRINSIC |
|
low complexity region
|
1006 |
1019 |
N/A |
INTRINSIC |
|
low complexity region
|
1076 |
1091 |
N/A |
INTRINSIC |
|
low complexity region
|
1195 |
1204 |
N/A |
INTRINSIC |
|
low complexity region
|
1273 |
1293 |
N/A |
INTRINSIC |
|
low complexity region
|
1355 |
1364 |
N/A |
INTRINSIC |
|
coiled coil region
|
1387 |
1429 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000138175
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.1%
- 20x: 96.9%
|
| Validation Efficiency |
97% (98/101) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex. [provided by RefSeq, Jul 2008]
PHENOTYPE: Male mice homozygous for a knock-out allele are sterile due to lack of axial element formation and subsequent failure of chromosome synapsis in prophase I spermatocytes, while females are subfertile with a sharply reduced litter size. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 99 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810021J22Rik |
T |
A |
11: 58,771,885 (GRCm39) |
C456S |
probably damaging |
Het |
| 4930524J08Rik |
T |
C |
5: 100,127,068 (GRCm39) |
|
probably benign |
Het |
| Adam28 |
T |
G |
14: 68,864,326 (GRCm39) |
R492S |
probably damaging |
Het |
| Adarb2 |
G |
A |
13: 8,807,313 (GRCm39) |
A705T |
possibly damaging |
Het |
| Adprhl1 |
T |
C |
8: 13,272,873 (GRCm39) |
D1295G |
probably benign |
Het |
| Aldh3b3 |
A |
G |
19: 4,016,476 (GRCm39) |
I365V |
probably benign |
Het |
| Aldh8a1 |
T |
C |
10: 21,264,996 (GRCm39) |
F208L |
possibly damaging |
Het |
| Ap3b1 |
G |
A |
13: 94,664,673 (GRCm39) |
V871I |
unknown |
Het |
| Apol7e |
A |
T |
15: 77,598,552 (GRCm39) |
R6* |
probably null |
Het |
| Arfgap3 |
T |
C |
15: 83,191,150 (GRCm39) |
E456G |
probably damaging |
Het |
| Arhgef1 |
T |
C |
7: 24,615,461 (GRCm39) |
L285P |
probably benign |
Het |
| Arhgef7 |
T |
A |
8: 11,850,861 (GRCm39) |
C315S |
probably benign |
Het |
| Atp9a |
A |
T |
2: 168,490,513 (GRCm39) |
L829Q |
probably damaging |
Het |
| Babam2 |
T |
A |
5: 31,888,393 (GRCm39) |
|
probably null |
Het |
| Bptf |
C |
T |
11: 106,951,384 (GRCm39) |
R2185H |
probably damaging |
Het |
| Brd9 |
A |
C |
13: 74,102,697 (GRCm39) |
M473L |
probably benign |
Het |
| C7 |
T |
C |
15: 5,041,538 (GRCm39) |
H456R |
probably benign |
Het |
| Cabp7 |
C |
A |
11: 4,688,856 (GRCm39) |
A205S |
probably damaging |
Het |
| Catsperb |
A |
G |
12: 101,554,293 (GRCm39) |
I662M |
probably damaging |
Het |
| Ccl21a |
T |
C |
4: 42,773,906 (GRCm39) |
M5V |
probably benign |
Het |
| Cdyl |
G |
T |
13: 36,042,177 (GRCm39) |
R405L |
possibly damaging |
Het |
| Cep89 |
T |
C |
7: 35,127,672 (GRCm39) |
L538P |
probably damaging |
Het |
| Cercam |
A |
G |
2: 29,762,892 (GRCm39) |
M209V |
possibly damaging |
Het |
| Chfr |
T |
A |
5: 110,310,571 (GRCm39) |
|
probably null |
Het |
| Cntnap5c |
T |
A |
17: 58,717,226 (GRCm39) |
Y1269* |
probably null |
Het |
| Col6a2 |
G |
T |
10: 76,439,170 (GRCm39) |
C833* |
probably null |
Het |
| Cpeb3 |
T |
A |
19: 37,151,900 (GRCm39) |
I159F |
probably benign |
Het |
| Cplx2 |
G |
A |
13: 54,526,663 (GRCm39) |
E24K |
possibly damaging |
Het |
| Ctsb |
A |
G |
14: 63,379,752 (GRCm39) |
T332A |
probably benign |
Het |
| Cyp2j12 |
T |
A |
4: 96,029,222 (GRCm39) |
T20S |
probably benign |
Het |
| Dcst2 |
T |
A |
3: 89,273,993 (GRCm39) |
H181Q |
probably damaging |
Het |
| Dnm1l |
T |
C |
16: 16,136,338 (GRCm39) |
I411V |
probably benign |
Het |
| Dock5 |
T |
A |
14: 68,046,479 (GRCm39) |
I768F |
probably benign |
Het |
| Ecel1 |
A |
G |
1: 87,077,334 (GRCm39) |
Y625H |
probably damaging |
Het |
| Efl1 |
T |
G |
7: 82,330,587 (GRCm39) |
S253R |
probably damaging |
Het |
| Elmod1 |
T |
A |
9: 53,820,127 (GRCm39) |
D287V |
probably damaging |
Het |
| Fam171a2 |
T |
C |
11: 102,329,491 (GRCm39) |
S423G |
probably benign |
Het |
| Fbxo8 |
A |
T |
8: 57,022,317 (GRCm39) |
|
probably null |
Het |
| Flnc |
G |
T |
6: 29,455,470 (GRCm39) |
G2040W |
probably damaging |
Het |
| Fras1 |
C |
T |
5: 96,821,458 (GRCm39) |
A1405V |
probably benign |
Het |
| Frem3 |
A |
C |
8: 81,342,392 (GRCm39) |
I1562L |
probably benign |
Het |
| Fxr1 |
C |
T |
3: 34,103,369 (GRCm39) |
A233V |
probably damaging |
Het |
| H1f9 |
A |
G |
11: 94,859,184 (GRCm39) |
R160G |
possibly damaging |
Het |
| Helb |
A |
G |
10: 119,944,799 (GRCm39) |
F246L |
probably damaging |
Het |
| Hoxb6 |
G |
T |
11: 96,183,510 (GRCm39) |
|
probably benign |
Het |
| Hspa2 |
A |
G |
12: 76,452,884 (GRCm39) |
E526G |
probably damaging |
Het |
| Hyal5 |
A |
T |
6: 24,875,983 (GRCm39) |
|
probably benign |
Het |
| Ints6 |
A |
T |
14: 62,942,224 (GRCm39) |
V503E |
probably benign |
Het |
| Ints9 |
C |
T |
14: 65,269,747 (GRCm39) |
T479I |
possibly damaging |
Het |
| Jag1 |
C |
T |
2: 136,926,975 (GRCm39) |
R928H |
probably benign |
Het |
| Lman2 |
A |
T |
13: 55,499,338 (GRCm39) |
I179N |
probably damaging |
Het |
| Lta |
T |
C |
17: 35,422,805 (GRCm39) |
S173G |
probably benign |
Het |
| Mki67 |
G |
A |
7: 135,300,099 (GRCm39) |
P1645L |
probably damaging |
Het |
| Mrc2 |
A |
T |
11: 105,183,609 (GRCm39) |
|
probably benign |
Het |
| Muc4 |
T |
A |
16: 32,754,689 (GRCm38) |
M1521K |
probably benign |
Het |
| Mucl3 |
T |
A |
17: 35,949,312 (GRCm39) |
T96S |
probably benign |
Het |
| Mylk3 |
T |
G |
8: 86,081,873 (GRCm39) |
D438A |
probably benign |
Het |
| Myo7a |
T |
A |
7: 97,700,833 (GRCm39) |
|
probably null |
Het |
| Nsmce4a |
G |
T |
7: 130,135,547 (GRCm39) |
Q342K |
probably benign |
Het |
| Or10ac1 |
A |
G |
6: 42,515,053 (GRCm39) |
I301T |
possibly damaging |
Het |
| Or4c124 |
T |
A |
2: 89,156,423 (GRCm39) |
I34F |
probably benign |
Het |
| Or5p60 |
A |
G |
7: 107,724,068 (GRCm39) |
L134P |
probably damaging |
Het |
| Or6c65 |
A |
T |
10: 129,604,136 (GRCm39) |
Y257F |
possibly damaging |
Het |
| Osbpl6 |
T |
A |
2: 76,423,730 (GRCm39) |
F864L |
probably damaging |
Het |
| Pla2g4a |
A |
G |
1: 149,808,438 (GRCm39) |
S2P |
probably benign |
Het |
| Plce1 |
T |
C |
19: 38,640,329 (GRCm39) |
L525P |
probably damaging |
Het |
| Por |
A |
T |
5: 135,763,773 (GRCm39) |
M667L |
probably benign |
Het |
| Psma4 |
T |
C |
9: 54,862,166 (GRCm39) |
Y97H |
probably benign |
Het |
| Qtrt1 |
A |
T |
9: 21,323,753 (GRCm39) |
H126L |
probably benign |
Het |
| Rab3a |
A |
T |
8: 71,209,170 (GRCm39) |
Y102F |
possibly damaging |
Het |
| Rnf212 |
T |
A |
5: 108,879,555 (GRCm39) |
H87L |
probably benign |
Het |
| Rnf216 |
A |
G |
5: 143,076,591 (GRCm39) |
S98P |
probably benign |
Het |
| Ryr1 |
G |
T |
7: 28,785,295 (GRCm39) |
R1806S |
probably benign |
Het |
| Scgb1b3 |
A |
T |
7: 31,075,262 (GRCm39) |
L37F |
probably benign |
Het |
| Sds |
T |
C |
5: 120,617,254 (GRCm39) |
S37P |
probably damaging |
Het |
| Senp6 |
A |
G |
9: 80,021,159 (GRCm39) |
R280G |
probably damaging |
Het |
| She |
T |
A |
3: 89,761,864 (GRCm39) |
I441K |
possibly damaging |
Het |
| Slc6a20b |
A |
G |
9: 123,436,682 (GRCm39) |
S244P |
possibly damaging |
Het |
| Slc9a3 |
A |
T |
13: 74,299,004 (GRCm39) |
Y141F |
probably damaging |
Het |
| Slco6c1 |
A |
T |
1: 97,009,207 (GRCm39) |
H426Q |
probably benign |
Het |
| Smc2 |
C |
A |
4: 52,440,301 (GRCm39) |
Q16K |
probably benign |
Het |
| Sphkap |
A |
C |
1: 83,241,547 (GRCm39) |
V1535G |
probably benign |
Het |
| Stard9 |
C |
A |
2: 120,532,633 (GRCm39) |
N2963K |
probably benign |
Het |
| Taar8a |
T |
C |
10: 23,952,762 (GRCm39) |
L122P |
probably damaging |
Het |
| Tab1 |
T |
A |
15: 80,044,445 (GRCm39) |
V491E |
probably benign |
Het |
| Tanc1 |
T |
C |
2: 59,636,688 (GRCm39) |
M857T |
probably benign |
Het |
| Tcirg1 |
C |
A |
19: 3,949,008 (GRCm39) |
R427L |
possibly damaging |
Het |
| Tmem109 |
A |
C |
19: 10,849,124 (GRCm39) |
*244G |
probably null |
Het |
| Tox2 |
A |
G |
2: 163,163,435 (GRCm39) |
Y136C |
|
Het |
| Tubb1 |
T |
C |
2: 174,298,825 (GRCm39) |
V169A |
possibly damaging |
Het |
| Ubr3 |
T |
C |
2: 69,783,886 (GRCm39) |
|
probably null |
Het |
| Vmn1r225 |
T |
A |
17: 20,723,059 (GRCm39) |
F167I |
probably benign |
Het |
| Vmn2r65 |
A |
C |
7: 84,595,569 (GRCm39) |
W372G |
probably damaging |
Het |
| Vps13a |
A |
T |
19: 16,727,537 (GRCm39) |
D188E |
probably damaging |
Het |
| Vsnl1 |
G |
T |
12: 11,376,439 (GRCm39) |
Q149K |
probably benign |
Het |
| Wdr35 |
A |
G |
12: 9,054,105 (GRCm39) |
N466S |
probably benign |
Het |
| Ywhae |
T |
A |
11: 75,650,169 (GRCm39) |
S210R |
probably damaging |
Het |
| Zfp28 |
T |
A |
7: 6,397,748 (GRCm39) |
S728T |
probably damaging |
Het |
| Zfpm1 |
A |
G |
8: 123,063,698 (GRCm39) |
D919G |
unknown |
Het |
|
| Other mutations in Sycp2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00484:Sycp2
|
APN |
2 |
178,024,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00578:Sycp2
|
APN |
2 |
177,992,615 (GRCm39) |
splice site |
probably benign |
|
|
IGL00646:Sycp2
|
APN |
2 |
178,016,252 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01309:Sycp2
|
APN |
2 |
177,999,904 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01464:Sycp2
|
APN |
2 |
178,043,425 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01539:Sycp2
|
APN |
2 |
178,016,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01670:Sycp2
|
APN |
2 |
178,019,843 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02138:Sycp2
|
APN |
2 |
178,043,783 (GRCm39) |
nonsense |
probably null |
|
|
IGL02138:Sycp2
|
APN |
2 |
178,000,047 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02630:Sycp2
|
APN |
2 |
178,043,712 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02673:Sycp2
|
APN |
2 |
178,036,004 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
IGL02961:Sycp2
|
APN |
2 |
178,022,655 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03084:Sycp2
|
APN |
2 |
178,033,584 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03123:Sycp2
|
APN |
2 |
177,994,272 (GRCm39) |
nonsense |
probably null |
|
|
IGL03167:Sycp2
|
APN |
2 |
178,021,291 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0043:Sycp2
|
UTSW |
2 |
178,006,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0050:Sycp2
|
UTSW |
2 |
178,006,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0096:Sycp2
|
UTSW |
2 |
178,045,528 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0096:Sycp2
|
UTSW |
2 |
178,045,528 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0310:Sycp2
|
UTSW |
2 |
178,023,648 (GRCm39) |
missense |
probably benign |
0.44 |
|
R0363:Sycp2
|
UTSW |
2 |
177,988,204 (GRCm39) |
splice site |
probably benign |
|
|
R0456:Sycp2
|
UTSW |
2 |
178,023,648 (GRCm39) |
missense |
probably benign |
0.44 |
|
R0597:Sycp2
|
UTSW |
2 |
177,998,373 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R0608:Sycp2
|
UTSW |
2 |
178,024,197 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1112:Sycp2
|
UTSW |
2 |
177,994,329 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1127:Sycp2
|
UTSW |
2 |
178,016,159 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R1208:Sycp2
|
UTSW |
2 |
177,998,421 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1208:Sycp2
|
UTSW |
2 |
177,998,421 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1323:Sycp2
|
UTSW |
2 |
177,989,414 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1323:Sycp2
|
UTSW |
2 |
177,989,414 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1413:Sycp2
|
UTSW |
2 |
177,989,590 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1557:Sycp2
|
UTSW |
2 |
178,037,009 (GRCm39) |
unclassified |
probably benign |
|
|
R1562:Sycp2
|
UTSW |
2 |
178,024,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1585:Sycp2
|
UTSW |
2 |
177,993,461 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1932:Sycp2
|
UTSW |
2 |
178,023,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1950:Sycp2
|
UTSW |
2 |
178,044,593 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2001:Sycp2
|
UTSW |
2 |
178,019,848 (GRCm39) |
missense |
probably benign |
0.05 |
|
R2105:Sycp2
|
UTSW |
2 |
177,991,931 (GRCm39) |
splice site |
probably null |
|
|
R2382:Sycp2
|
UTSW |
2 |
178,019,811 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2403:Sycp2
|
UTSW |
2 |
178,045,528 (GRCm39) |
nonsense |
probably null |
|
|
R2483:Sycp2
|
UTSW |
2 |
178,016,388 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3003:Sycp2
|
UTSW |
2 |
177,999,916 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3418:Sycp2
|
UTSW |
2 |
178,043,446 (GRCm39) |
splice site |
probably benign |
|
|
R3686:Sycp2
|
UTSW |
2 |
178,016,177 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4038:Sycp2
|
UTSW |
2 |
178,022,720 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4039:Sycp2
|
UTSW |
2 |
178,022,720 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4272:Sycp2
|
UTSW |
2 |
178,000,017 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4343:Sycp2
|
UTSW |
2 |
178,022,740 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4491:Sycp2
|
UTSW |
2 |
178,016,778 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4534:Sycp2
|
UTSW |
2 |
177,996,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4720:Sycp2
|
UTSW |
2 |
178,016,225 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4805:Sycp2
|
UTSW |
2 |
178,035,754 (GRCm39) |
unclassified |
probably benign |
|
|
R4807:Sycp2
|
UTSW |
2 |
178,035,754 (GRCm39) |
unclassified |
probably benign |
|
|
R4808:Sycp2
|
UTSW |
2 |
178,035,754 (GRCm39) |
unclassified |
probably benign |
|
|
R4906:Sycp2
|
UTSW |
2 |
178,045,450 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4910:Sycp2
|
UTSW |
2 |
178,000,017 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5282:Sycp2
|
UTSW |
2 |
178,045,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5285:Sycp2
|
UTSW |
2 |
178,034,191 (GRCm39) |
splice site |
probably null |
|
|
R5316:Sycp2
|
UTSW |
2 |
177,998,296 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5389:Sycp2
|
UTSW |
2 |
178,019,495 (GRCm39) |
splice site |
probably null |
|
|
R5621:Sycp2
|
UTSW |
2 |
178,023,711 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5652:Sycp2
|
UTSW |
2 |
178,000,498 (GRCm39) |
splice site |
probably null |
|
|
R5880:Sycp2
|
UTSW |
2 |
178,016,263 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6114:Sycp2
|
UTSW |
2 |
177,990,038 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6115:Sycp2
|
UTSW |
2 |
177,990,038 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6186:Sycp2
|
UTSW |
2 |
178,025,353 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6351:Sycp2
|
UTSW |
2 |
178,005,209 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6509:Sycp2
|
UTSW |
2 |
178,037,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6536:Sycp2
|
UTSW |
2 |
177,993,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6679:Sycp2
|
UTSW |
2 |
178,022,721 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6687:Sycp2
|
UTSW |
2 |
177,996,753 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6761:Sycp2
|
UTSW |
2 |
178,016,144 (GRCm39) |
splice site |
probably null |
|
|
R6786:Sycp2
|
UTSW |
2 |
178,025,345 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7357:Sycp2
|
UTSW |
2 |
178,045,597 (GRCm39) |
splice site |
probably null |
|
|
R7519:Sycp2
|
UTSW |
2 |
177,988,126 (GRCm39) |
makesense |
probably null |
|
|
R7805:Sycp2
|
UTSW |
2 |
178,022,651 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7960:Sycp2
|
UTSW |
2 |
178,046,453 (GRCm39) |
missense |
probably null |
0.90 |
|
R8022:Sycp2
|
UTSW |
2 |
177,996,855 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8037:Sycp2
|
UTSW |
2 |
178,045,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8038:Sycp2
|
UTSW |
2 |
178,045,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8039:Sycp2
|
UTSW |
2 |
178,016,378 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8159:Sycp2
|
UTSW |
2 |
177,996,770 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8233:Sycp2
|
UTSW |
2 |
177,998,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8436:Sycp2
|
UTSW |
2 |
178,004,761 (GRCm39) |
missense |
probably benign |
0.44 |
|
R8437:Sycp2
|
UTSW |
2 |
178,006,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8528:Sycp2
|
UTSW |
2 |
178,016,326 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8679:Sycp2
|
UTSW |
2 |
177,992,768 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8711:Sycp2
|
UTSW |
2 |
177,990,088 (GRCm39) |
missense |
probably benign |
0.41 |
|
R8843:Sycp2
|
UTSW |
2 |
177,990,052 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9044:Sycp2
|
UTSW |
2 |
177,989,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9067:Sycp2
|
UTSW |
2 |
177,989,214 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9203:Sycp2
|
UTSW |
2 |
177,996,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9263:Sycp2
|
UTSW |
2 |
178,035,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9301:Sycp2
|
UTSW |
2 |
178,023,650 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9596:Sycp2
|
UTSW |
2 |
177,990,212 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9633:Sycp2
|
UTSW |
2 |
177,998,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9715:Sycp2
|
UTSW |
2 |
178,035,957 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9748:Sycp2
|
UTSW |
2 |
178,025,304 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Sycp2
|
UTSW |
2 |
178,023,727 (GRCm39) |
missense |
probably benign |
0.17 |
|
Z1088:Sycp2
|
UTSW |
2 |
178,016,160 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Sycp2
|
UTSW |
2 |
178,006,674 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Sycp2
|
UTSW |
2 |
178,022,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1191:Sycp2
|
UTSW |
2 |
177,992,662 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACCTTCTTTTATCACCAAGAATGCC -3'
(R):5'- GTGTGCCCACCTAGTGATAGTTAG -3'
Sequencing Primer
(F):5'- CCAAGAATGCCATTTACCAAGTTGAG -3'
(R):5'- TGTTTTTATGCCTTACGAAATGGAG -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation