Incidental Mutation 'R7424:Mtus1'
| ID |
575925 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mtus1
|
| Ensembl Gene |
ENSMUSG00000045636 |
| Gene Name |
mitochondrial tumor suppressor 1 |
| Synonyms |
MTSG1, B430305I03Rik, MD44, Atip1 |
| MMRRC Submission |
045502-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.241)
|
| Stock # |
R7424 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
8 |
| Chromosomal Location |
41443951-41586763 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 41475443 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Phenylalanine
at position 184
(V184F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091252
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000051379]
[ENSMUST00000059115]
[ENSMUST00000093534]
[ENSMUST00000118835]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000051379
AA Change: V104F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000053554
Gene: ENSMUSG00000045636
AA Change: V104F
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
106 |
168 |
N/A |
INTRINSIC |
|
coiled coil region
|
193 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
425 |
439 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000059115
AA Change: V874F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000059503
Gene: ENSMUSG00000045636
AA Change: V874F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
524 |
539 |
N/A |
INTRINSIC |
|
coiled coil region
|
876 |
938 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
1021 |
1156 |
3e-7 |
SMART |
|
low complexity region
|
1195 |
1209 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000093534
AA Change: V184F
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000091252
Gene: ENSMUSG00000045636
AA Change: V184F
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
186 |
248 |
N/A |
INTRINSIC |
|
coiled coil region
|
273 |
455 |
N/A |
INTRINSIC |
|
low complexity region
|
505 |
519 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000118835
AA Change: V874F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000112626
Gene: ENSMUSG00000045636
AA Change: V874F
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
524 |
539 |
N/A |
INTRINSIC |
|
coiled coil region
|
876 |
938 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
1021 |
1156 |
3e-7 |
SMART |
|
low complexity region
|
1195 |
1209 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.6552 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
99% (76/77) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit spontaneous heart hypertrophy and SLE-like lymphoproliferative disease. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 6430548M08Rik |
C |
T |
8: 120,872,284 (GRCm39) |
R71C |
probably damaging |
Het |
| Aanat |
A |
T |
11: 116,486,455 (GRCm39) |
|
probably benign |
Het |
| Ahrr |
G |
T |
13: 74,405,664 (GRCm39) |
S91* |
probably null |
Het |
| Ampd1 |
A |
T |
3: 102,995,758 (GRCm39) |
N223Y |
probably benign |
Het |
| Ankar |
T |
G |
1: 72,719,217 (GRCm39) |
N544T |
probably damaging |
Het |
| Ankk1 |
A |
G |
9: 49,330,050 (GRCm39) |
S302P |
possibly damaging |
Het |
| Bcr |
T |
C |
10: 74,992,932 (GRCm39) |
V809A |
probably benign |
Het |
| Bpifb2 |
A |
G |
2: 153,732,460 (GRCm39) |
N353S |
possibly damaging |
Het |
| Cyth1 |
A |
T |
11: 118,074,835 (GRCm39) |
|
probably null |
Het |
| Ddx5 |
A |
T |
11: 106,673,006 (GRCm39) |
N506K |
probably benign |
Het |
| Dnaja1 |
A |
T |
4: 40,730,244 (GRCm39) |
I239F |
probably benign |
Het |
| Ethe1 |
C |
T |
7: 24,305,676 (GRCm39) |
T141I |
probably damaging |
Het |
| Fhip2b |
T |
C |
14: 70,831,447 (GRCm39) |
H29R |
probably damaging |
Het |
| Gdap2 |
A |
T |
3: 100,109,382 (GRCm39) |
I36F |
unknown |
Het |
| Gm13030 |
A |
T |
4: 138,598,577 (GRCm39) |
D115E |
unknown |
Het |
| Gm17019 |
A |
T |
5: 15,079,386 (GRCm39) |
L227Q |
probably damaging |
Het |
| Gm9195 |
T |
A |
14: 72,673,217 (GRCm39) |
E2517D |
possibly damaging |
Het |
| Gramd2a |
T |
A |
9: 59,615,354 (GRCm39) |
V39D |
possibly damaging |
Het |
| Hmcn1 |
C |
T |
1: 150,506,017 (GRCm39) |
W3836* |
probably null |
Het |
| Hspa14 |
C |
T |
2: 3,490,078 (GRCm39) |
D494N |
possibly damaging |
Het |
| Ifit2 |
A |
G |
19: 34,550,598 (GRCm39) |
N46S |
probably benign |
Het |
| Ifna6 |
A |
T |
4: 88,746,044 (GRCm39) |
E131V |
possibly damaging |
Het |
| Ift140 |
T |
C |
17: 25,256,010 (GRCm39) |
V504A |
possibly damaging |
Het |
| Irgc |
T |
C |
7: 24,131,653 (GRCm39) |
N388S |
probably damaging |
Het |
| Itgal |
T |
A |
7: 126,916,537 (GRCm39) |
V743E |
probably benign |
Het |
| Itih5 |
T |
C |
2: 10,250,448 (GRCm39) |
S716P |
probably damaging |
Het |
| Kcnab1 |
A |
T |
3: 65,173,924 (GRCm39) |
K78N |
possibly damaging |
Het |
| Kif1a |
A |
T |
1: 92,982,039 (GRCm39) |
V787E |
possibly damaging |
Het |
| Krt15 |
A |
T |
11: 100,026,386 (GRCm39) |
V100E |
possibly damaging |
Het |
| Krt39 |
A |
T |
11: 99,408,917 (GRCm39) |
V293E |
probably damaging |
Het |
| Lrrn4 |
A |
G |
2: 132,711,663 (GRCm39) |
F720S |
possibly damaging |
Het |
| Map2 |
G |
A |
1: 66,453,983 (GRCm39) |
A958T |
possibly damaging |
Het |
| Map3k9 |
A |
G |
12: 81,770,871 (GRCm39) |
S906P |
probably benign |
Het |
| Mdc1 |
T |
C |
17: 36,164,201 (GRCm39) |
S1250P |
probably benign |
Het |
| Meltf |
G |
A |
16: 31,703,764 (GRCm39) |
V164I |
probably damaging |
Het |
| Mtap |
T |
G |
4: 89,097,699 (GRCm39) |
|
probably null |
Het |
| Myh1 |
A |
T |
11: 67,104,489 (GRCm39) |
D1015V |
probably damaging |
Het |
| Ndrg1 |
T |
C |
15: 66,816,787 (GRCm39) |
|
probably null |
Het |
| Nkd1 |
G |
T |
8: 89,311,803 (GRCm39) |
V130L |
probably benign |
Het |
| Nsfl1c |
A |
G |
2: 151,342,673 (GRCm39) |
D81G |
probably benign |
Het |
| Nt5c1b |
T |
A |
12: 10,431,391 (GRCm39) |
|
probably null |
Het |
| Nucb1 |
T |
C |
7: 45,148,202 (GRCm39) |
K204E |
possibly damaging |
Het |
| Nwd1 |
T |
G |
8: 73,401,801 (GRCm39) |
M774R |
possibly damaging |
Het |
| Or2m13 |
A |
T |
16: 19,225,944 (GRCm39) |
V274E |
probably damaging |
Het |
| Or52u1 |
G |
C |
7: 104,237,907 (GRCm39) |
E299Q |
probably damaging |
Het |
| Or5an1c |
A |
T |
19: 12,218,318 (GRCm39) |
S236T |
possibly damaging |
Het |
| Pan3 |
T |
A |
5: 147,473,082 (GRCm39) |
|
probably null |
Het |
| Pcdh15 |
A |
T |
10: 74,342,317 (GRCm39) |
T1135S |
probably benign |
Het |
| Pfas |
A |
G |
11: 68,890,918 (GRCm39) |
I331T |
probably damaging |
Het |
| Plxna2 |
T |
A |
1: 194,488,647 (GRCm39) |
I1641N |
probably damaging |
Het |
| Pramel27 |
C |
T |
4: 143,579,779 (GRCm39) |
P455S |
probably benign |
Het |
| Ptar1 |
A |
T |
19: 23,695,465 (GRCm39) |
R311W |
probably damaging |
Het |
| Ranbp2 |
T |
G |
10: 58,315,016 (GRCm39) |
M1912R |
probably damaging |
Het |
| Rbm12 |
A |
G |
2: 155,939,223 (GRCm39) |
F350L |
possibly damaging |
Het |
| Sdhaf1 |
T |
C |
7: 30,021,468 (GRCm39) |
D96G |
probably benign |
Het |
| Serpinb6b |
T |
A |
13: 33,152,650 (GRCm39) |
M53K |
probably damaging |
Het |
| Sh2d6 |
A |
T |
6: 72,494,147 (GRCm39) |
L147Q |
probably benign |
Het |
| Slc19a2 |
T |
A |
1: 164,088,445 (GRCm39) |
C298S |
probably benign |
Het |
| Son |
AGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCG |
AGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCG |
16: 91,457,222 (GRCm39) |
|
probably benign |
Het |
| St8sia2 |
T |
A |
7: 73,610,650 (GRCm39) |
Q211L |
possibly damaging |
Het |
| Sult2a2 |
T |
C |
7: 13,468,822 (GRCm39) |
I96T |
possibly damaging |
Het |
| Tab2 |
G |
T |
10: 7,783,247 (GRCm39) |
H678Q |
probably damaging |
Het |
| Tnfaip6 |
A |
G |
2: 51,928,228 (GRCm39) |
E14G |
probably benign |
Het |
| Trip11 |
A |
T |
12: 101,851,457 (GRCm39) |
L869H |
probably damaging |
Het |
| Tslp |
T |
C |
18: 32,952,133 (GRCm39) |
Y133H |
not run |
Het |
| Ttn |
T |
C |
2: 76,571,334 (GRCm39) |
I26520V |
probably damaging |
Het |
| Ttn |
A |
G |
2: 76,762,487 (GRCm39) |
V3374A |
unknown |
Het |
| Tubgcp2 |
T |
A |
7: 139,587,837 (GRCm39) |
I263F |
possibly damaging |
Het |
| Uaca |
A |
G |
9: 60,777,392 (GRCm39) |
E593G |
probably damaging |
Het |
| Unc13b |
C |
T |
4: 43,172,235 (GRCm39) |
T1021I |
unknown |
Het |
| Ush1c |
T |
A |
7: 45,874,979 (GRCm39) |
I131F |
probably benign |
Het |
| Usp24 |
C |
A |
4: 106,236,304 (GRCm39) |
D997E |
probably benign |
Het |
| Usp54 |
T |
C |
14: 20,627,108 (GRCm39) |
T517A |
probably benign |
Het |
| Vmn1r151 |
A |
T |
7: 22,198,505 (GRCm39) |
M200K |
possibly damaging |
Het |
| Vmn2r43 |
T |
C |
7: 8,258,328 (GRCm39) |
D295G |
probably damaging |
Het |
| Vmn2r70 |
G |
A |
7: 85,213,076 (GRCm39) |
P444S |
probably damaging |
Het |
| Vmn2r85 |
G |
T |
10: 130,254,849 (GRCm39) |
P612T |
probably damaging |
Het |
| Vps13d |
A |
T |
4: 144,875,317 (GRCm39) |
V1736D |
|
Het |
| Zbtb11 |
A |
T |
16: 55,810,850 (GRCm39) |
H336L |
probably benign |
Het |
|
| Other mutations in Mtus1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00708:Mtus1
|
APN |
8 |
41,537,386 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01377:Mtus1
|
APN |
8 |
41,536,172 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01472:Mtus1
|
APN |
8 |
41,455,449 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01995:Mtus1
|
APN |
8 |
41,537,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02027:Mtus1
|
APN |
8 |
41,446,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02381:Mtus1
|
APN |
8 |
41,536,156 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02571:Mtus1
|
APN |
8 |
41,536,519 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02936:Mtus1
|
APN |
8 |
41,452,554 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0116:Mtus1
|
UTSW |
8 |
41,451,514 (GRCm39) |
unclassified |
probably benign |
|
|
R0139:Mtus1
|
UTSW |
8 |
41,469,233 (GRCm39) |
splice site |
probably benign |
|
|
R0178:Mtus1
|
UTSW |
8 |
41,455,398 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0179:Mtus1
|
UTSW |
8 |
41,455,398 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0220:Mtus1
|
UTSW |
8 |
41,447,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0324:Mtus1
|
UTSW |
8 |
41,537,432 (GRCm39) |
missense |
probably benign |
|
|
R0355:Mtus1
|
UTSW |
8 |
41,535,965 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0357:Mtus1
|
UTSW |
8 |
41,536,563 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R0464:Mtus1
|
UTSW |
8 |
41,455,511 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0681:Mtus1
|
UTSW |
8 |
41,446,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1016:Mtus1
|
UTSW |
8 |
41,503,063 (GRCm39) |
missense |
probably benign |
0.43 |
|
R1570:Mtus1
|
UTSW |
8 |
41,529,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1579:Mtus1
|
UTSW |
8 |
41,535,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1607:Mtus1
|
UTSW |
8 |
41,468,446 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1869:Mtus1
|
UTSW |
8 |
41,529,267 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1888:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1888:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1891:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1894:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2063:Mtus1
|
UTSW |
8 |
41,535,745 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2111:Mtus1
|
UTSW |
8 |
41,475,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2112:Mtus1
|
UTSW |
8 |
41,475,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2224:Mtus1
|
UTSW |
8 |
41,535,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2226:Mtus1
|
UTSW |
8 |
41,535,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2227:Mtus1
|
UTSW |
8 |
41,535,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2516:Mtus1
|
UTSW |
8 |
41,535,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3414:Mtus1
|
UTSW |
8 |
41,501,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3899:Mtus1
|
UTSW |
8 |
41,536,166 (GRCm39) |
missense |
probably benign |
|
|
R4096:Mtus1
|
UTSW |
8 |
41,537,284 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4831:Mtus1
|
UTSW |
8 |
41,536,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4850:Mtus1
|
UTSW |
8 |
41,537,507 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4916:Mtus1
|
UTSW |
8 |
41,453,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4940:Mtus1
|
UTSW |
8 |
41,494,515 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R4988:Mtus1
|
UTSW |
8 |
41,537,578 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5133:Mtus1
|
UTSW |
8 |
41,536,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5468:Mtus1
|
UTSW |
8 |
41,537,615 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5598:Mtus1
|
UTSW |
8 |
41,475,592 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5782:Mtus1
|
UTSW |
8 |
41,535,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5860:Mtus1
|
UTSW |
8 |
41,529,303 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5900:Mtus1
|
UTSW |
8 |
41,536,534 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5943:Mtus1
|
UTSW |
8 |
41,537,302 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6019:Mtus1
|
UTSW |
8 |
41,536,077 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6125:Mtus1
|
UTSW |
8 |
41,537,576 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6197:Mtus1
|
UTSW |
8 |
41,537,074 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6488:Mtus1
|
UTSW |
8 |
41,494,545 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R6869:Mtus1
|
UTSW |
8 |
41,535,691 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7117:Mtus1
|
UTSW |
8 |
41,536,621 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7126:Mtus1
|
UTSW |
8 |
41,468,439 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7213:Mtus1
|
UTSW |
8 |
41,537,524 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7308:Mtus1
|
UTSW |
8 |
41,535,965 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7481:Mtus1
|
UTSW |
8 |
41,537,652 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7485:Mtus1
|
UTSW |
8 |
41,537,590 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7660:Mtus1
|
UTSW |
8 |
41,469,248 (GRCm39) |
missense |
probably benign |
|
|
R7699:Mtus1
|
UTSW |
8 |
41,537,006 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7700:Mtus1
|
UTSW |
8 |
41,537,006 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7709:Mtus1
|
UTSW |
8 |
41,507,687 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7791:Mtus1
|
UTSW |
8 |
41,536,417 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8196:Mtus1
|
UTSW |
8 |
41,509,689 (GRCm39) |
missense |
probably benign |
|
|
R8463:Mtus1
|
UTSW |
8 |
41,536,271 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8724:Mtus1
|
UTSW |
8 |
41,451,500 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9047:Mtus1
|
UTSW |
8 |
41,536,760 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9092:Mtus1
|
UTSW |
8 |
41,455,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9283:Mtus1
|
UTSW |
8 |
41,536,519 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9313:Mtus1
|
UTSW |
8 |
41,535,923 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9329:Mtus1
|
UTSW |
8 |
41,537,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9603:Mtus1
|
UTSW |
8 |
41,536,795 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9711:Mtus1
|
UTSW |
8 |
41,536,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAATTATAGTTTGGGGCATGGC -3'
(R):5'- ATCCCAGGAGCCTATGCATC -3'
Sequencing Primer
(F):5'- TTCGTGCTAGTGAGAAACCC -3'
(R):5'- GGAGCCTATGCATCCAGAC -3'
|
| Posted On |
2019-10-07 |
Incidental Mutation