Mutagenetix > Incidental Mutation

Incidental Mutation 'R7424:Ranbp2'

575933

Institutional Source

Beutler Lab

Gene Symbol

Ranbp2

Ensembl Gene

ENSMUSG00000003226

Gene Name

RAN binding protein 2

Synonyms

A430087B05Rik

MMRRC Submission

045502-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R7424 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

58446920-58494356 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to G at 58479194 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Methionine to Arginine at position 1912 (M1912R)

Ref Sequence

ENSEMBL: ENSMUSP00000003310 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000003310]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000003310
AA Change: M1912R

PolyPhen 2 Score 0.977 (Sensitivity: 0.76; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000003310
Gene: ENSMUSG00000003226
AA Change: M1912R

Domain	Start	End	E-Value	Type
Pfam:TPR_1	60	93	1.8e-7	PFAM
Pfam:TPR_8	60	93	8.9e-6	PFAM
low complexity region	235	247	N/A	INTRINSIC
low complexity region	778	801	N/A	INTRINSIC
coiled coil region	808	832	N/A	INTRINSIC
RanBD	1166	1295	6.47e-64	SMART
ZnF_RBZ	1348	1372	5.49e-2	SMART
ZnF_RBZ	1412	1436	3.06e-6	SMART
ZnF_RBZ	1471	1495	4.16e-8	SMART
ZnF_RBZ	1500	1524	4.57e-5	SMART
ZnF_RBZ	1560	1584	3.52e-6	SMART
ZnF_RBZ	1619	1643	1.35e-7	SMART
RanBD	1850	1979	2.84e-60	SMART
low complexity region	2034	2048	N/A	INTRINSIC
low complexity region	2069	2090	N/A	INTRINSIC
low complexity region	2106	2121	N/A	INTRINSIC
RanBD	2147	2276	4.96e-83	SMART
low complexity region	2310	2317	N/A	INTRINSIC
low complexity region	2328	2342	N/A	INTRINSIC
Pfam:IR1-M	2468	2530	2.5e-27	PFAM
Pfam:IR1-M	2544	2604	7e-30	PFAM
low complexity region	2673	2684	N/A	INTRINSIC
low complexity region	2722	2732	N/A	INTRINSIC
RanBD	2741	2869	5e-79	SMART
Pfam:Pro_isomerase	2896	3052	4.5e-45	PFAM

Meta Mutation Damage Score

0.7516

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.4%

Validation Efficiency

99% (76/77)

MGI Phenotype

PHENOTYPE: Mice homozygous for a gene trap allele display embryonic lethality. Heterozygous mice on some backgrounds display reduced ATP levels in the CNS, decreased glucose clearance, decreased weight gain on a high fat diet, and reduced scotopic responses. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 79 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
6430548M08Rik	C	T	8: 120,145,545 (GRCm38)	R71C	probably damaging	Het
Aanat	A	T	11: 116,595,629 (GRCm38)		probably benign	Het
Ahrr	G	T	13: 74,257,545 (GRCm38)	S91*	probably null	Het
Ampd1	A	T	3: 103,088,442 (GRCm38)	N223Y	probably benign	Het
Ankar	T	G	1: 72,680,058 (GRCm38)	N544T	probably damaging	Het
Ankk1	A	G	9: 49,418,750 (GRCm38)	S302P	possibly damaging	Het
Bcr	T	C	10: 75,157,100 (GRCm38)	V809A	probably benign	Het
Bpifb2	A	G	2: 153,890,540 (GRCm38)	N353S	possibly damaging	Het
Cyth1	A	T	11: 118,184,009 (GRCm38)		probably null	Het
Ddx5	A	T	11: 106,782,180 (GRCm38)	N506K	probably benign	Het
Dnaja1	A	T	4: 40,730,244 (GRCm38)	I239F	probably benign	Het
Ethe1	C	T	7: 24,606,251 (GRCm38)	T141I	probably damaging	Het
Fhip2b	T	C	14: 70,594,007 (GRCm38)	H29R	probably damaging	Het
Gdap2	A	T	3: 100,202,066 (GRCm38)	I36F	unknown	Het
Gm13030	A	T	4: 138,871,266 (GRCm38)	D115E	unknown	Het
Gm17019	A	T	5: 15,029,372 (GRCm38)	L227Q	probably damaging	Het
Gm9195	T	A	14: 72,435,777 (GRCm38)	E2517D	possibly damaging	Het
Gramd2a	T	A	9: 59,708,071 (GRCm38)	V39D	possibly damaging	Het
Hmcn1	C	T	1: 150,630,266 (GRCm38)	W3836*	probably null	Het
Hspa14	C	T	2: 3,489,041 (GRCm38)	D494N	possibly damaging	Het
Ifit2	A	G	19: 34,573,198 (GRCm38)	N46S	probably benign	Het
Ifna6	A	T	4: 88,827,807 (GRCm38)	E131V	possibly damaging	Het
Ift140	T	C	17: 25,037,036 (GRCm38)	V504A	possibly damaging	Het
Irgc	T	C	7: 24,432,228 (GRCm38)	N388S	probably damaging	Het
Itgal	T	A	7: 127,317,365 (GRCm38)	V743E	probably benign	Het
Itih5	T	C	2: 10,245,637 (GRCm38)	S716P	probably damaging	Het
Kcnab1	A	T	3: 65,266,503 (GRCm38)	K78N	possibly damaging	Het
Kif1a	A	T	1: 93,054,317 (GRCm38)	V787E	possibly damaging	Het
Krt15	A	T	11: 100,135,560 (GRCm38)	V100E	possibly damaging	Het
Krt39	A	T	11: 99,518,091 (GRCm38)	V293E	probably damaging	Het
Lrrn4	A	G	2: 132,869,743 (GRCm38)	F720S	possibly damaging	Het
Map2	G	A	1: 66,414,824 (GRCm38)	A958T	possibly damaging	Het
Map3k9	A	G	12: 81,724,097 (GRCm38)	S906P	probably benign	Het
Mdc1	T	C	17: 35,853,309 (GRCm38)	S1250P	probably benign	Het
Meltf	G	A	16: 31,884,946 (GRCm38)	V164I	probably damaging	Het
Mtap	T	G	4: 89,179,462 (GRCm38)		probably null	Het
Mtus1	C	A	8: 41,022,406 (GRCm38)	V184F	probably damaging	Het
Myh1	A	T	11: 67,213,663 (GRCm38)	D1015V	probably damaging	Het
Ndrg1	T	C	15: 66,944,938 (GRCm38)		probably null	Het
Nkd1	G	T	8: 88,585,175 (GRCm38)	V130L	probably benign	Het
Nsfl1c	A	G	2: 151,500,753 (GRCm38)	D81G	probably benign	Het
Nt5c1b	T	A	12: 10,381,391 (GRCm38)		probably null	Het
Nucb1	T	C	7: 45,498,778 (GRCm38)	K204E	possibly damaging	Het
Nwd1	T	G	8: 72,675,173 (GRCm38)	M774R	possibly damaging	Het
Or2m13	A	T	16: 19,407,194 (GRCm38)	V274E	probably damaging	Het
Or52u1	G	C	7: 104,588,700 (GRCm38)	E299Q	probably damaging	Het
Or5an1c	A	T	19: 12,240,954 (GRCm38)	S236T	possibly damaging	Het
Pan3	T	A	5: 147,536,272 (GRCm38)		probably null	Het
Pcdh15	A	T	10: 74,506,485 (GRCm38)	T1135S	probably benign	Het
Pfas	A	G	11: 69,000,092 (GRCm38)	I331T	probably damaging	Het
Plxna2	T	A	1: 194,806,339 (GRCm38)	I1641N	probably damaging	Het
Pramel27	C	T	4: 143,853,209 (GRCm38)	P455S	probably benign	Het
Ptar1	A	T	19: 23,718,101 (GRCm38)	R311W	probably damaging	Het
Rbm12	A	G	2: 156,097,303 (GRCm38)	F350L	possibly damaging	Het
Sdhaf1	T	C	7: 30,322,043 (GRCm38)	D96G	probably benign	Het
Serpinb6b	T	A	13: 32,968,667 (GRCm38)	M53K	probably damaging	Het
Sh2d6	A	T	6: 72,517,164 (GRCm38)	L147Q	probably benign	Het
Slc19a2	T	A	1: 164,260,876 (GRCm38)	C298S	probably benign	Het
Son	AGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCG	AGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCGCAGGAGCCGAACCCCCAGCCG	16: 91,660,334 (GRCm38)		probably benign	Het
St8sia2	T	A	7: 73,960,902 (GRCm38)	Q211L	possibly damaging	Het
Sult2a2	T	C	7: 13,734,897 (GRCm38)	I96T	possibly damaging	Het
Tab2	G	T	10: 7,907,483 (GRCm38)	H678Q	probably damaging	Het
Tnfaip6	A	G	2: 52,038,216 (GRCm38)	E14G	probably benign	Het
Trip11	A	T	12: 101,885,198 (GRCm38)	L869H	probably damaging	Het
Tslp	T	C	18: 32,819,080 (GRCm38)	Y133H	not run	Het
Ttn	A	G	2: 76,932,143 (GRCm38)	V3374A	unknown	Het
Ttn	T	C	2: 76,740,990 (GRCm38)	I26520V	probably damaging	Het
Tubgcp2	T	A	7: 140,007,924 (GRCm38)	I263F	possibly damaging	Het
Uaca	A	G	9: 60,870,110 (GRCm38)	E593G	probably damaging	Het
Unc13b	C	T	4: 43,172,235 (GRCm38)	T1021I	unknown	Het
Ush1c	T	A	7: 46,225,555 (GRCm38)	I131F	probably benign	Het
Usp24	C	A	4: 106,379,107 (GRCm38)	D997E	probably benign	Het
Usp54	T	C	14: 20,577,040 (GRCm38)	T517A	probably benign	Het
Vmn1r151	A	T	7: 22,499,080 (GRCm38)	M200K	possibly damaging	Het
Vmn2r43	T	C	7: 8,255,329 (GRCm38)	D295G	probably damaging	Het
Vmn2r70	G	A	7: 85,563,868 (GRCm38)	P444S	probably damaging	Het
Vmn2r85	G	T	10: 130,418,980 (GRCm38)	P612T	probably damaging	Het
Vps13d	A	T	4: 145,148,747 (GRCm38)	V1736D		Het
Zbtb11	A	T	16: 55,990,487 (GRCm38)	H336L	probably benign	Het

Other mutations in Ranbp2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00229:Ranbp2	APN	10	58,477,256 (GRCm38)	missense	probably damaging	1.00
IGL00336:Ranbp2	APN	10	58,451,984 (GRCm38)	missense	probably damaging	1.00
IGL00486:Ranbp2	APN	10	58,477,612 (GRCm38)	missense	probably benign	0.06
IGL00800:Ranbp2	APN	10	58,490,704 (GRCm38)	missense	probably benign
IGL00834:Ranbp2	APN	10	58,453,323 (GRCm38)	missense	possibly damaging	0.94
IGL00852:Ranbp2	APN	10	58,477,901 (GRCm38)	missense	probably benign
IGL00984:Ranbp2	APN	10	58,461,964 (GRCm38)	nonsense	probably null
IGL01299:Ranbp2	APN	10	58,492,817 (GRCm38)	missense	probably damaging	1.00
IGL01325:Ranbp2	APN	10	58,476,298 (GRCm38)	missense	probably damaging	0.99
IGL01444:Ranbp2	APN	10	58,475,300 (GRCm38)	missense	possibly damaging	0.79
IGL01545:Ranbp2	APN	10	58,478,881 (GRCm38)	missense	possibly damaging	0.48
IGL01619:Ranbp2	APN	10	58,464,078 (GRCm38)	splice site	probably null
IGL01782:Ranbp2	APN	10	58,478,309 (GRCm38)	missense	probably damaging	0.97
IGL02020:Ranbp2	APN	10	58,479,947 (GRCm38)	missense	probably damaging	1.00
IGL02096:Ranbp2	APN	10	58,461,967 (GRCm38)	missense	probably damaging	1.00
IGL02182:Ranbp2	APN	10	58,485,760 (GRCm38)	nonsense	probably null
IGL02211:Ranbp2	APN	10	58,478,242 (GRCm38)	missense	probably benign
IGL02249:Ranbp2	APN	10	58,480,078 (GRCm38)	missense	possibly damaging	0.89
IGL02268:Ranbp2	APN	10	58,493,653 (GRCm38)	unclassified	probably benign
IGL02421:Ranbp2	APN	10	58,480,554 (GRCm38)	missense	probably damaging	1.00
IGL03080:Ranbp2	APN	10	58,476,791 (GRCm38)	missense	probably benign	0.01
IGL03119:Ranbp2	APN	10	58,452,003 (GRCm38)	missense	probably damaging	1.00
IGL03206:Ranbp2	APN	10	58,465,547 (GRCm38)	missense	probably damaging	1.00
IGL03237:Ranbp2	APN	10	58,492,961 (GRCm38)	missense	probably damaging	0.98
En_passant	UTSW	10	58,452,017 (GRCm38)	missense	probably damaging	1.00
red_river	UTSW	10	58,465,667 (GRCm38)	missense	probably damaging	1.00
IGL02799:Ranbp2	UTSW	10	58,480,264 (GRCm38)	missense	probably damaging	1.00
R0058:Ranbp2	UTSW	10	58,480,531 (GRCm38)	missense	probably damaging	0.98
R0058:Ranbp2	UTSW	10	58,480,531 (GRCm38)	missense	probably damaging	0.98
R0145:Ranbp2	UTSW	10	58,480,046 (GRCm38)	missense	probably damaging	1.00
R0309:Ranbp2	UTSW	10	58,479,868 (GRCm38)	missense	probably benign	0.04
R0375:Ranbp2	UTSW	10	58,477,283 (GRCm38)	missense	probably damaging	1.00
R0441:Ranbp2	UTSW	10	58,485,768 (GRCm38)	missense	probably benign	0.40
R0494:Ranbp2	UTSW	10	58,467,432 (GRCm38)	missense	possibly damaging	0.53
R0542:Ranbp2	UTSW	10	58,478,414 (GRCm38)	missense	probably benign	0.02
R0565:Ranbp2	UTSW	10	58,476,336 (GRCm38)	missense	probably benign	0.41
R0608:Ranbp2	UTSW	10	58,493,898 (GRCm38)	missense	probably damaging	1.00
R0661:Ranbp2	UTSW	10	58,478,733 (GRCm38)	missense	probably benign
R0670:Ranbp2	UTSW	10	58,480,698 (GRCm38)	missense	probably benign	0.01
R0760:Ranbp2	UTSW	10	58,476,791 (GRCm38)	missense	possibly damaging	0.70
R0811:Ranbp2	UTSW	10	58,465,529 (GRCm38)	missense	probably benign	0.01
R0812:Ranbp2	UTSW	10	58,465,529 (GRCm38)	missense	probably benign	0.01
R1180:Ranbp2	UTSW	10	58,465,463 (GRCm38)	missense	probably damaging	1.00
R1196:Ranbp2	UTSW	10	58,477,053 (GRCm38)	missense	probably damaging	1.00
R1216:Ranbp2	UTSW	10	58,483,212 (GRCm38)	splice site	probably benign
R1374:Ranbp2	UTSW	10	58,485,893 (GRCm38)	splice site	probably benign
R1541:Ranbp2	UTSW	10	58,483,094 (GRCm38)	missense	possibly damaging	0.90
R1589:Ranbp2	UTSW	10	58,463,986 (GRCm38)	missense	probably benign	0.01
R1711:Ranbp2	UTSW	10	58,460,519 (GRCm38)	missense	probably benign	0.11
R1761:Ranbp2	UTSW	10	58,485,741 (GRCm38)	missense	probably benign	0.02
R1831:Ranbp2	UTSW	10	58,479,222 (GRCm38)	nonsense	probably null
R1840:Ranbp2	UTSW	10	58,478,766 (GRCm38)	missense	probably benign	0.41
R1869:Ranbp2	UTSW	10	58,492,561 (GRCm38)	missense	probably damaging	1.00
R1871:Ranbp2	UTSW	10	58,492,561 (GRCm38)	missense	probably damaging	1.00
R1892:Ranbp2	UTSW	10	58,464,099 (GRCm38)	missense	probably benign	0.36
R2270:Ranbp2	UTSW	10	58,455,927 (GRCm38)	missense	probably benign	0.06
R2363:Ranbp2	UTSW	10	58,478,936 (GRCm38)	missense	possibly damaging	0.79
R3844:Ranbp2	UTSW	10	58,477,895 (GRCm38)	missense	possibly damaging	0.87
R3937:Ranbp2	UTSW	10	58,476,472 (GRCm38)	missense	probably benign	0.00
R3938:Ranbp2	UTSW	10	58,476,472 (GRCm38)	missense	probably benign	0.00
R4025:Ranbp2	UTSW	10	58,480,556 (GRCm38)	missense	probably benign	0.23
R4183:Ranbp2	UTSW	10	58,465,666 (GRCm38)	missense	possibly damaging	0.53
R4247:Ranbp2	UTSW	10	58,478,864 (GRCm38)	missense	possibly damaging	0.79
R4334:Ranbp2	UTSW	10	58,463,994 (GRCm38)	missense	probably damaging	1.00
R4656:Ranbp2	UTSW	10	58,453,422 (GRCm38)	missense	possibly damaging	0.82
R4746:Ranbp2	UTSW	10	58,492,670 (GRCm38)	missense	probably damaging	1.00
R4852:Ranbp2	UTSW	10	58,477,056 (GRCm38)	missense	possibly damaging	0.94
R4863:Ranbp2	UTSW	10	58,492,421 (GRCm38)	missense	probably damaging	0.99
R5011:Ranbp2	UTSW	10	58,461,895 (GRCm38)	missense	probably benign	0.36
R5014:Ranbp2	UTSW	10	58,464,120 (GRCm38)	missense	probably benign	0.40
R5145:Ranbp2	UTSW	10	58,480,038 (GRCm38)	missense	probably damaging	1.00
R5178:Ranbp2	UTSW	10	58,476,785 (GRCm38)	missense	probably benign	0.01
R5199:Ranbp2	UTSW	10	58,464,443 (GRCm38)	missense	probably benign
R5294:Ranbp2	UTSW	10	58,478,668 (GRCm38)	missense	probably benign	0.23
R5508:Ranbp2	UTSW	10	58,480,005 (GRCm38)	missense	probably damaging	0.97
R5511:Ranbp2	UTSW	10	58,493,739 (GRCm38)	missense	probably benign	0.29
R5575:Ranbp2	UTSW	10	58,492,583 (GRCm38)	missense	probably damaging	1.00
R5617:Ranbp2	UTSW	10	58,465,667 (GRCm38)	missense	probably damaging	1.00
R5630:Ranbp2	UTSW	10	58,479,076 (GRCm38)	missense	probably damaging	1.00
R5733:Ranbp2	UTSW	10	58,485,836 (GRCm38)	missense	probably damaging	1.00
R5751:Ranbp2	UTSW	10	58,464,264 (GRCm38)	splice site	probably null
R5767:Ranbp2	UTSW	10	58,476,825 (GRCm38)	missense	probably benign	0.02
R6122:Ranbp2	UTSW	10	58,465,529 (GRCm38)	missense	probably benign	0.02
R6147:Ranbp2	UTSW	10	58,479,428 (GRCm38)	missense	probably damaging	1.00
R6286:Ranbp2	UTSW	10	58,479,572 (GRCm38)	missense	probably benign	0.02
R6344:Ranbp2	UTSW	10	58,483,886 (GRCm38)	splice site	probably null
R6452:Ranbp2	UTSW	10	58,478,157 (GRCm38)	missense	probably benign	0.00
R6487:Ranbp2	UTSW	10	58,485,741 (GRCm38)	missense	probably benign	0.02
R6620:Ranbp2	UTSW	10	58,455,807 (GRCm38)	critical splice acceptor site	probably null
R6759:Ranbp2	UTSW	10	58,457,737 (GRCm38)	nonsense	probably null
R7010:Ranbp2	UTSW	10	58,454,571 (GRCm38)	critical splice acceptor site	probably null
R7071:Ranbp2	UTSW	10	58,492,837 (GRCm38)	missense	probably damaging	1.00
R7083:Ranbp2	UTSW	10	58,479,230 (GRCm38)	missense	probably damaging	1.00
R7088:Ranbp2	UTSW	10	58,463,906 (GRCm38)	missense	probably damaging	1.00
R7102:Ranbp2	UTSW	10	58,463,950 (GRCm38)	missense	probably damaging	1.00
R7194:Ranbp2	UTSW	10	58,476,769 (GRCm38)	missense	probably benign	0.05
R7217:Ranbp2	UTSW	10	58,452,017 (GRCm38)	missense	probably damaging	1.00
R7318:Ranbp2	UTSW	10	58,483,087 (GRCm38)	nonsense	probably null
R7341:Ranbp2	UTSW	10	58,485,797 (GRCm38)	missense	possibly damaging	0.72
R7398:Ranbp2	UTSW	10	58,467,277 (GRCm38)	missense	probably damaging	1.00
R7727:Ranbp2	UTSW	10	58,455,438 (GRCm38)	missense	probably benign	0.09
R7795:Ranbp2	UTSW	10	58,483,907 (GRCm38)	nonsense	probably null
R7812:Ranbp2	UTSW	10	58,467,402 (GRCm38)	missense	probably benign
R7845:Ranbp2	UTSW	10	58,447,022 (GRCm38)	missense	probably damaging	1.00
R7875:Ranbp2	UTSW	10	58,478,455 (GRCm38)	nonsense	probably null
R7934:Ranbp2	UTSW	10	58,476,475 (GRCm38)	missense	probably damaging	0.98
R8022:Ranbp2	UTSW	10	58,485,861 (GRCm38)	missense	possibly damaging	0.53
R8050:Ranbp2	UTSW	10	58,479,619 (GRCm38)	missense	probably damaging	0.99
R8100:Ranbp2	UTSW	10	58,490,648 (GRCm38)	missense	possibly damaging	0.58
R8194:Ranbp2	UTSW	10	58,455,925 (GRCm38)	missense	possibly damaging	0.84
R8258:Ranbp2	UTSW	10	58,455,933 (GRCm38)	missense	probably benign	0.04
R8259:Ranbp2	UTSW	10	58,455,933 (GRCm38)	missense	probably benign	0.04
R8461:Ranbp2	UTSW	10	58,476,394 (GRCm38)	missense	probably damaging	0.97
R8722:Ranbp2	UTSW	10	58,476,227 (GRCm38)	missense	probably damaging	1.00
R8755:Ranbp2	UTSW	10	58,465,147 (GRCm38)	nonsense	probably null
R8794:Ranbp2	UTSW	10	58,492,592 (GRCm38)	missense	probably damaging	1.00
R8879:Ranbp2	UTSW	10	58,477,889 (GRCm38)	missense	probably benign	0.10
R8994:Ranbp2	UTSW	10	58,480,069 (GRCm38)	missense	possibly damaging	0.89
R9023:Ranbp2	UTSW	10	58,479,521 (GRCm38)	nonsense	probably null
R9124:Ranbp2	UTSW	10	58,492,897 (GRCm38)	missense	probably benign	0.01
R9133:Ranbp2	UTSW	10	58,477,228 (GRCm38)	missense	probably damaging	1.00
R9145:Ranbp2	UTSW	10	58,455,914 (GRCm38)	missense	probably benign	0.03
R9190:Ranbp2	UTSW	10	58,477,295 (GRCm38)	missense	probably damaging	1.00
R9369:Ranbp2	UTSW	10	58,480,664 (GRCm38)	missense	probably benign	0.04
R9394:Ranbp2	UTSW	10	58,455,876 (GRCm38)	missense	probably damaging	0.97
R9642:Ranbp2	UTSW	10	58,483,085 (GRCm38)	missense	probably damaging	0.99
R9673:Ranbp2	UTSW	10	58,465,141 (GRCm38)	missense	probably damaging	1.00
X0018:Ranbp2	UTSW	10	58,478,584 (GRCm38)	missense	probably benign	0.13
X0022:Ranbp2	UTSW	10	58,465,155 (GRCm38)	missense	probably benign	0.33
Z1088:Ranbp2	UTSW	10	58,492,893 (GRCm38)	missense	probably benign	0.35
Z1088:Ranbp2	UTSW	10	58,477,983 (GRCm38)	frame shift	probably null
Z1088:Ranbp2	UTSW	10	58,477,972 (GRCm38)	frame shift	probably null
Z1176:Ranbp2	UTSW	10	58,461,886 (GRCm38)	missense	probably damaging	1.00
Z1177:Ranbp2	UTSW	10	58,493,891 (GRCm38)	nonsense	probably null

Predicted Primers

PCR Primer
(F):5'- TTGAGCCAGTAGTGCAGATG -3'
(R):5'- TAAGAGAAGACGTTGACACTCCTC -3'

Sequencing Primer
(F):5'- CCAGTAGTGCAGATGCCAGAAAAG -3'
(R):5'- GAATTCTTCAGCTAGCTCTGGCG -3'

Posted On

2019-10-07